Program Snapshot

Childhood cancers and structural birth defects have profound, lifelong effects on patients and their families. While researchers are increasingly identifying the underlying biological causes of these conditions, the role of genetics is not yet fully understood. A better understanding will spur development of prevention, early detection, and therapeutic interventions. The Common Fund’s Gabriella Miller Kids First Pediatric Research Program (Kids First) is developing a large-scale data resource that will capitalize on exciting advances in genetics research. The resource will allow researchers everywhere access to vast amounts of childhood cancer and structural birth defects genetics data that will greatly accelerate their research. In addition, there is considerable scientific evidence that examining childhood cancer and structural birth defects together will uncover new connections between them that would not have been uncovered had one or the other been examined independently. By integrating large amounts of genetic data from patients with childhood cancer and structural birth defects, Kids First will facilitate new discoveries and novel ways of thinking about these conditions. This is anticipated to accelerate scientific progress in pediatric research that will improve the lives of the children and families impacted by these conditions.

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This page last reviewed on March 28, 2018