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​​The NIH Common Fund and the American Recovery and Reinvestment Act (ARRA)

FUNDED RESEARCH

Common Fund Awards $38.4M in ARRA Funds in Fiscal Year 2010

During fiscal year 2010 (October 1, 2009 - September 30, 2010) the NIH Common Fund made nine new American Recovery and Reinvestment Act (ARRA) awards totaling $38.4M. These programs of research are unique and highly innovative, and have the potential to dramatically accelerate discovery in biomedicine and development of new treatments for myriad diseases and disorders. For example, Thomas Grabowski (University of Washington) and colleagues are using new systems neuroimaging approaches to investigate age-related cognitive decline, neurodegenerative diseases (including Alzheimer disease and Parkinson's disease), and rehabilitation of paralysis using brain-computer interfaces (1RC4NS073008-01). In contrast, Mitchell Kronenberg (La Jolla Institute for Allergy and Immunology) and colleagues are constructing a screening facility that provides the " libraries" of molecular reagents and instrumentation needed to conduct large-scale investigations of how the body fights off infectious and autoimmune diseases and cancers (1RC4AI092763-01). In another highly innovative program of research, Cameron Currie (University of Wisconsin - Madison) and colleagues are using "high-throughput screening" and mouse models of disease to first identify and then evaluate the anti-infective potential of small molecules derived from untapped sources of natural products (1RC4GM096347-01).

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RFA-OD-10-005: Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4)
PI Name Institution Name Title
CURRIE, CAMERON ROBERT UNIVERSITY OF WISCONSIN MADISON Discovery of natural product-based drugs from bacterial symbionts of insectsThis award is funded through the American Recovery and Reinvestment Act
GRABOWSKI, THOMAS J. UNIVERSITY OF WASHINGTON IBIC: Integrated Brain Imaging Center for the University of WashingtonThis award is funded through the American Recovery and Reinvestment Act
KIRSCHNER, MARC WALLACE HARVARD UNIVERSITY (MEDICAL SCHOOL) Quantifying post-translational modifications and protein expression by HTP-MSThis award is funded through the American Recovery and Reinvestment Act
KRONENBERG, MITCHELL LA JOLLA INST FOR ALLERGY & IMMUNOLGY New players in immune function: identification through RNAi and micro-RNA screensThis award is funded through the American Recovery and Reinvestment Act
SPIEGELMAN, BRUCE M. DANA-FARBER CANCER INSTITUTE Regulation of Brown Fat: Toward New Therapy for Human ObesityThis award is funded through the American Recovery and Reinvestment Act
SUTCLIFFE, JULIE L UNIVERSITY OF CALIFORNIA DAVIS High throughput design, synthesis and in vivo evaluation of targeted molecular imThis award is funded through the American Recovery and Reinvestment Act
VIDAL, MARC DANA-FARBER CANCER INSTITUTE Generation and validation of a comprehensive human disease mutant ORF resourceThis award is funded through the American Recovery and Reinvestment Act
WEIR, DAVID R. UNIVERSITY OF MICHIGAN AT ANN ARBOR Expanding a National Resource for Genetic Research in Behavioral & Health ScienceThis award is funded through the American Recovery and Reinvestment Act
WERNIG, MARIUS STANFORD UNIVERSITY Dissecting the mechanism of direct neural induction through genomic interrogationThis award is funded through the American Recovery and Reinvestment Act

 

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RFA-0D-09-003: NIH Challenge Grants in Health and Science Research (RC1)
Science, Technology, Engineering and Mathematics (S.T.E.M.) Education Common Fund Challenge Awards
PI Name Institution Name Title
BAO, LEI OHIO STATE UNIVERSITY This award is funded through the American Recovery and Reinvestment ActThis award is funded through the American Recovery and Reinvestment Act
BOTTOMLEY, LAURA JONES (contact); 
LAVELLE, JEROME
NORTH CAROLINA STATE UNIVERSITY RALEIGH Do Engineering Curricula Improve Science and Mathematics Learning in Elementary SThis award is funded through the American Recovery and Reinvestment Act
GOLINKOFF, ROBERTA MICHNICK UNIVERSITY OF DELAWARE Shape Up Preschoolers Geometric Sense Predicts Future Mathematics AchievementThis award is funded through the American Recovery and Reinvestment Act
GRISSMER, DAVID W. UNIVERSITY OF VIRGINIA CHARLOTTESVILLE Improving Fine Motor Skill Development to Promote Mathematical AbilityThis award is funded through the American Recovery and Reinvestment Act
HURTADO, SYLVIA UNIVERSITY OF CALIFORNIA LOS ANGELES Introductory S.T.E.M. Courses: Sorting, Harvesting, or Nurturing Student TalentThis award is funded through the American Recovery and Reinvestment Act
JITENDRA, ASHA KIRON UNIVERSITY OF MINNESOTA TWIN CITIES Improving Problem-Solving Performance of Students with Mathematics DifficultiesThis award is funded through the American Recovery and Reinvestment Act
KELLMAN, PHILIP J UNIVERSITY OF CALIFORNIA LOS ANGELES Using Perceptual and Adaptive Learning to Advance Chemistry EducationThis award is funded through the American Recovery and Reinvestment Act
PIASTA, SHAYNE B. OHIO STATE UNIVERSITY Efficacy of the Core Knowledge Approach to Math and Science Preschool InstructionThis award is funded through the American Recovery and Reinvestment Act
PRITCHARD, DAVID E MASSACHUSETTS INSTITUTE OF TECHNOLOGY Integrating and Evaluating the Modeling Applied to Problem Solving PedagogyThis award is funded through the American Recovery and Reinvestment Act
SADLER, PHILIP MICHAEL HARVARD UNIVERSITY ALSISE: Assessment of Life Science Intermediate School EducatorsThis award is funded through the American Recovery and Reinvestment Act
SHAPIRO, JENESSA UNIVERSITY OF CALIFORNIA LOS ANGELES Reducing Barriers to Gender Equity in S.T.E.M. Fields by Reducing Stereotype ThreatsThis award is funded through the American Recovery and Reinvestment Act
SHEPHERD, VIRGINIA L VANDERBILT UNIVERSITY Evaluation of the Impact of a Sustained Scientist-in-the-Classroom ProgramThis award is funded through the American Recovery and Reinvestment Act
WENDELL, DOUGLAS L (contact)
PICKARD, DAWN M.
OAKLAND UNIVERSITY DNA Markers for Fast Plants to Teach Scientific ThinkingThis award is funded through the American Recovery and Reinvestment Act
Other Common Fund Challenge Awards
CHEN, LIN (contact);
PETASIS, NICOS A
UNIVERSITY OF SOUTHERN CALIFORNIA Mechanism-based small molecule epigenetic modulators: Targeting specific HDACsThis award is funded through the American Recovery and Reinvestment Act
COOK, KARON FRANCES UNIVERSITY OF WASHINGTON Development and Validation of Measures of Pain Behaviors in Chronic PainThis award is funded through the American Recovery and Reinvestment Act
FRYE, STEPHEN VERNON UNIVERSITY OF NORTH CAROLINA CHAPEL HILL Discovery of Small Molecule MBT Domain AntagonistsThis award is funded through the American Recovery and Reinvestment Act
KOIDE, SHOHEI UNIVERSITY OF CHICAGO Renewable synthetic antibodies for epigenomicsThis award is funded through the American Recovery and Reinvestment Act
MCMURRAY, CYNTHIA THERESE (contact);
NORTHEN, TRENT R.
UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB MT Function and Dysfunction in Single Neurons in VivoThis award is funded through the American Recovery and Reinvestment Act
PRELICH, GREGORY ALBERT EINSTEIN COL OF MED YESHIVA UNIV Identification of Small Molecule Inhibitors of SUMOylationThis award is funded through the American Recovery and Reinvestment Act
VUORI, KRISTIINA BURNHAM INSTITUTE FOR MEDICAL RESEARCH High throughput screening in human 3D spheroids of epithelial, endothelial, and sThis award is funded through the American Recovery and Reinvestment Act
WANSINK, BRIAN CORNELL UNIVERSITY ITHACA Nudging Nutrition: Setting Healthier Defaults in Stores and in HomesThis award is funded through the American Recovery and Reinvestment Act
ZHOU, MING-MING (contact)
WALSH, MARTIN JOHN
MOUNT SINAI SCHOOL OF MEDICINE OF NYU A Novel Epigenetic Gene Silencing TechnologyThis award is funded through the American Recovery and Reinvestment Act

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RFA-OD-09-004: Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure "Grand Opportunities"; (RC2)
PI Name Institution Name Title
ABRAMSON, STEVEN B (contact); 
LITTMAN, DAN R.
NEW YORK UNIVERSITY SCHOOL OF MEDICINE Role of oral and intestinal microbiota in Rheumatoid ArthritisThis award is funded through the American Recovery and Reinvestment Act
BUCHWALD, DEDRA S. UNIVERSITY OF WASHINGTON Building a Unique National Community Based Twin RepositoryThis award is funded through the American Recovery and Reinvestment Act
COOKE, JOHN P. STANFORD UNIVERSITY NCE-based strategy for nuclear reprogramming and regenerative medicineThis award is funded through the American Recovery and Reinvestment Act
CRITSER, JOHN K. UNIVERSITY OF MISSOURI-COLUMBIA Development of humanized models using human induced pluripotent stem cellsThis award is funded through the American Recovery and Reinvestment Act
FOX, GEOFFREY C. INDIANA UNIVERSITY BLOOMINGTON Investigation of Cloud Computing to Support Data-Parallel Health ResearchThis award is funded through the American Recovery and Reinvestment Act
KHARRAZI, MARTIN SEQUOIA FOUNDATION Development of a Research-Ready Pregnancy and Newborn Biobank in CaliforniaThis award is funded through the American Recovery and Reinvestment Act
LARK, MICHAEL WILLIAM TREVENA, INC. Selective modulation of GPCR signal transduction with biased ligandsThis award is funded through the American Recovery and Reinvestment Act
MEURICE, NATHALIE (contact); 
HULME, CHRISTOPHER ; 
MOUSSES, SPYRO
TRANSLATIONAL GENOMICS RESEARCH INST The Southwest Comprehensive Center for Drug Discovery and DevelopmentThis award is funded through the American Recovery and Reinvestment Act
MORITZ, ROBERT L (contact);
HOOD, LEROY E.
INSTITUTE FOR SYS.T.E.M.S BIOLOGY Complete Human Peptide- and MRM-AtlasThis award is funded through the American Recovery and Reinvestment Act
MOSKOWITZ, JAY UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA An Open Source Research Permissions Framework for South Carolina
VOLPP, KEVIN G (contact);
ASCH, DAVID A.
UNIVERSITY OF PENNSYLVANIA Developing Interactive Technologies to Improve Research and Health BehaviorThis award is funded through the American Recovery and Reinvestment Act

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NOT-OD-09-060: Administrative Supplements Providing Summer Research Experiences
PI Name Institution Name Title
CHRISTMAN, KAREN L UNIVERSITY OF CALIFORNIA SAN DIEGO Engineering a Dynamic Extracellular Matrix MicroenvironmentThis award is funded through the American Recovery and Reinvestment Act
SHERLEY, JAMES L BOSTON BIOMEDICAL RESEARCH INSTITUTE NIH Director's Pioneer AwardThis award is funded through the American Recovery and Reinvestment Act
TOOMRE, DEREK K. YALE UNIVERSITY Novel TIRF microscopy analyzing trafficking & signaling at the cell cortexThis award is funded through the American Recovery and Reinvestment Act

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NOT-OD-09-058: Recovery Act Limited Competition for Revision Applications
PI Name Institution Name Title
FIDOCK, DAVID ARMAND COLUMBIA UNIVERSITY HEALTH SCIENCES A Cell-based HTS for Delayed Death Inhibitors of the Malarial Parasite PlastidThis award is funded through the American Recovery and Reinvestment Act

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NOT-OD-09-056: Recovery Act Funds for Administrative Supplements
PI Name Institution Name Title
GOZANI, OR P. (contact);
BEDFORD, MARK T.
STANFORD UNIVERSITY Applying peptide and protein domain microarrays to epigenetic researchThis award is funded through the American Recovery and Reinvestment Act
KIKINIS, RON BRIGHAM AND WOMEN'S HOSPITAL National Alliance-Medical Imaging Computing (NAMIC)(RMI)
KNIGHT, ROBIN UNIVERSITY OF COLORADO AT BOULDER New Tools for Understanding the Composition and Dynamics of Microbial CommunitiesThis award is funded through the American Recovery and Reinvestment Act
WHITE, OWEN R UNIVERSITY OF MARYLAND BALTIMORE A Quality Assurance, Coordination and Analysis Center for HMPThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-09-003: 2009 NIH Director's New Innovator Award Program (DP2)
PI Name Institution Name Title
BANERJEE, IPSITA UNIVERSITY OF PITTSBURGH AT PITTSBURGH Defining Mechanisms Controlling Stem Cell Fate During DifferentiationThis award is funded through the American Recovery and Reinvestment Act
CAMARGO, FERNANDO CHILDREN'S HOSPITAL BOSTON Analysis Of Stem Cell Dynamics And Differentiation By Cellular BarcodingThis award is funded through the American Recovery and Reinvestment Act
CHRONIS, NIKOLAOS UNIVERSITY OF MICHIGAN AT ANN ARBOR A Biochip For Point-Of-Care Hiv/Aids Diagnosis In The Developing WorldThis award is funded through the American Recovery and Reinvestment Act
ORDWAY, DIANE JOYCE COLORADO STATE UNIVERSITY-FORT COLLINS Immune Modulation By Highly Virulent Clinical Isolates Of M.TuberculosisThis award is funded through the American Recovery and Reinvestment Act
SONNENBURG, JUSTIN STANFORD UNIVERSITY Discovery of gut microbiota-targeted small molecules: new tools and therapeuticsThis award is funded through the American Recovery and Reinvestment Act
TAVAZOIE, SOHAIL F ROCKEFELLER UNIVERSITY The discovery of microRNAs that predict chemotherapeutic responsiveness of cancerThis award is funded through the American Recovery and Reinvestment Act
WEINBERGER, LEOR S UNIVERSITY OF CALIFORNIA SAN DIEGO Developing Transmissible Antivirals by Exploiting Gene-Expression CircuitryThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-07-012: Technology Development in Epigenetics (R21)
PI Name Institution Name Title
JAFFE, JACOB DAVID BROAD INSTITUTE, INC. Direct detection of epigenetic modifications in their native chromatin contextsThis award is funded through the American Recovery and Reinvestment Act
RFA-RM-07-015: Discovery of Novel Epigenetic Marks in Mammalian Cells (R01)
PI Name Institution Name Title
KIKYO, NOBUAKI UNIVERSITY OF MINNESOTA TWIN CITIES Histone proline isomerization and gene regulationThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-07-016: Discovery of Novel Epigenetic Marks in Mammalian Cells (R21)
PI Name Institution Name Title
PARTHUN, MARK R (contact); 
FREITAS, MICHAEL A
OHIO STATE UNIVERSITY Identification of Histone Modification Interaction NetworksThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-08-001: Construction of a Reference Sequence Data Set for the Human Microbiome Project (U54)
PI Name Institution Name Title
NELSON, KAREN E J. CRAIG VENTER INSTITUTE, INC. Construction of A Reference Sequence Data Set For The Human Microbiome ProjectThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-08-023: Patient-Reported Outcomes Measurement Information SystemTM (PROMIS) Research Sites (U01)
PI Name Institution Name Title
STONE, ARTHUR A. (contact); 
BRODERICK, JOAN E
STATE UNIVERSITY NEW YORK STONY BROOK Ecological validity of PROMIS instrumentsThis award is funded through the American Recovery and Reinvestment Act

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RFA-RM-08-025: Patient-Reported Outcomes Measurement Information SystemTM (PROMIS) Statistical Center (U54)
PI Name Institution Name Title
CELLA, DAVID EVANSTON NORTHWESTERN HEALTHCARE PROMIS Statistical CenterThis award is funded through the American Recovery and Reinvestment Act
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