High-Risk, High-Reward Research Program

NIH Director's Transformative Research Award

NIH Director's Transformative Research Award

Part of the High-Risk, High-Reward Research program, the award supports exceptionally innovative, unconventional, paradigm-shifting research projects that are inherently risky and untested.

  • Open to all career stages
  • Open to individuals or teams
  • No preliminary data required
  • No limits to budget
  • Effort commensurate to project needs
  • Clinical research proposals should follow NIH Institute-specific guidelines


Application Information

Funding Opportunities
FY 2018

Closed September 15, 2017

See NOT-OD-17-106 & NOT-OD-17-111 for NIH response to Hurricane Harvey
See NOT-OD-17-113 for NIH response to Hurricane Irma

               NIH Director's Transformative Research Award FAQs

Join our Listserv or contact us at Transformative_Awards@mail.nih.gov

This page last reviewed on March 6, 2018