The Common Fund's Genotype-Tissue Expression (GTEx) program aims to study human gene expression and regulation in multiple tissues, providing valuable insights into the mechanisms of gene regulation and, in the future, its disease-related perturbations. Genetic variation between individuals will be examined for correlation with differences in gene expression level to identify regions of the genome that influence whether and how much a gene is expressed. The GTEx project includes the following initiatives:
GTEX pilot project described as one of the most ambitious tissue-collection studies - Nature’s Technology Feature “Building Better Biobanks”
The June 2012 issue of Nature, highlights efforts being made to store high-quality, data-rich biological samples that are essential for research. In the article, GTEx Coordinator Dr. Jeff Struewing, M.D., M.S. (NHGRI) and other members of the GTEx Working Group discuss the various steps throughout the collection process where attention to detail results in high-quality specimens.
Reference: Nature 2012 June; Volume 486
Common Fund Launches Pilot Phase of the Genotype-Tissue Expression (GTEx) Project
The Common Fund is supporting projects to create resources that researchers can use to study inherited susceptibility to illness, including a tissue bank for future biological studies.
Read the press release...