We Accelerate Discovery

You are here


Program Snapshot

With advances in genomic sequencing and medicine, it is now possible to examine patients with rare genetic diseases at a level that allows physicians and scientists to find the “needle in a haystack”. Often times, one small change (mutation) in a genetic sequence can cause an individual to develop disease symptoms. To increase the capacity for this type of research, an Undiagnosed Diseases Network (UDN) is being established across the country to diagnose both rare and new diseases. Furthermore, through the support of mechanistic studies, the Network hopes to aid in management strategies for the patients. This program will advance laboratory and clinical research, building upon the experience and expertise of the NIH Intramural Undiagnosed Diseases Program (UDP) and similar programs, to enhance coordination and collaboration among laboratory and clinical researchers across multiple centers. The Network will benefit from having the capacity to share data and approaches widely throughout the scientific community.

Read more…

Program Highlights

Expanding the limits of modern medicine. The NIH Undiagnosed Diseases Network will address an abundance of mystery cases. Read a news feature about patients and the network here

UDN Logo

NEW! Undiagnosed Diseases Gene Function Research Awardees
Who Is in the Network?

The UDN is a group of clinical and research centers across the United States. The clinical sites are the Baylor College of Medicine Duke Medical Center Harvard Affiliated Hospitals  (Brigham and Women’s Hospital, Boston Children’s Hospital, Massachusetts General Hospital), the NIH Undiagnosed Diseases ProgramStanford Medical Center University of California at Los Angeles  Medical Center, and Vanderbilt University Medical Center . The Coordinating Center  for the UDN is at Harvard Medical School, and the two Sequencing Cores that perform genetic testing for the UDN are at the Baylor College of Medicine  and the Medical College of Wisconsin .


2015 Bio-IT World Best Practices Awards Winners Announced

UDPICS wins Editors' Choice Award: the Undiagnosed Diseases Program developed the Undiagnosed Diseases Integrated Collaboration System (UDPICS), which consists of a database of patient and biological information, an analytics environment, and electronic notebooks for recording the work of the investigators.  

Undiagnosed Diseases


Up to Top