The Common Fund’s Regulatory Science program is a collaborative effort to accelerate the development and use of new tools, standards and approaches to efficiently develop medical products and to more effectively evaluate medical product safety, efficacy and quality. The current phase of the program focuses on the development of cutting edge microphysiological systems (MPS), or “tissue chips”, to more accurately predict drug safety and efficacy in humans.
Female ‘Organs-on-a-chip’ Capable of Replicating Complex Hormonal Cycles. A study from Regulatory Science researchers led by Dr. Teresa Woodruff has created a miniature, artificial model of the human female reproductive system that can undergo a complete 28 day menstrual cycle in the laboratory. This technology could eventually be used to study new drug toxicity to this complex organ system without the need for animal models. Read More.
- 'Organs on a Chip' named a Top Ten Emerging Technology for 2016 by The World Economic Forum. Read about the full list in Scientific American.
- NIH Director's Blog: If I Only Had a Brain? Tissue Chips Predict Neurotoxicity
- Researchers Create Artificial Organs That Fit In Your Hand (NPR)
- In the New Yorker article: “Of Mice and Micro-Organs.”
- On WXXI News, read and listen to: “Human-on-a-chip” featuring MPS members from the NIH Center for Advancing Translational Sciences.
- In a special supplement to Volume 4 of the journal Stem Cell Research & Therapy.
- Vanderbilt’s neurovascular chip project moves into new phase
National Center for Advancing Translational Sciences (NCATS) site: Tissue Chip for Drug Screening program
Chip is an interactive model that can help you learn about the innovative developments from the Tissue Chip program.
For more information about the Tissue Chip program, watch the new video from the National Center for Advancing Translational Sciences (NCATS).