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Program Snapshot

The NIH Common Fund’s Metabolomics program aims to increase national capacity in metabolomics by supporting the development of next generation technologies to enhance the sensitivity and speed with which specific elements of the cellular metabolome can be identified and quantified, providing training and mentoring opportunities, increasing the inventory of chemically identifiable metabolites through the synthesis and availability of high quality reference standards, and by promoting data sharing and collaboration. Learn more here

Program Highlights

Metablomics Highlight

Antibiotics treatment leads to harmful infection by decreasing key metabolites A new paper from Metabolomics Program researcher Dr. Casey Theriot demonstrates the role that key metabolites play in preventing infection after antibiotic treatment. Read a brief description of the research.

Metabolomics Scientists Tie Metabolites to Lifespan in Mammals Research from a group including NIH Common Fund’s Metabolomics Program grantee Sun Hee Yim used the latest metabolomics techniques to look at a wide range of metabolites from 26 diverse species of mammals.  They were able to correlate the levels of specific metabolites with the range of lifespans that exists across the mammals sampled, providing insight into biological mechanisms of longevity. Read more about this research.

Features of the Metabolomics Workbench highlighted in a recent publication
A new publication highlights the Metabolomics Workbench, created by the Metabolomics Program’s Data Repository and Coordination Center, and describes how to access resources from the Metabolomics Program. For additional information and to read a brief description of the research article.

Taming the Torrent of Metabolic Data
Molecular structures of norcocaine and metoclopramide​Metabolomics Program grantee, Dr. Oliver Fiehn at the NIH West Coast Metabolomics Center at UC Davis, and his colleagues in Japan, have developed open source software called MS-DIAL to help researchers analyze their untargeted metabolomics data. Read a brief description of the research.

Learn more about the Metabolomics Community


The NIH Common Fund Metabolomics Program supports international data sharing through the MetabolomeXchange.

In April 2014, representatives from Australia, Canada, Germany, Japan, the Netherlands and the United States NIH Common Fund Metabolomics program met to discuss an international data exchange in metabolomics. The participants agreed to create a portal that would provide a network of coordinated and freely accessible metabolomics data collected from repositories around the world. As a result of this meeting and in collaboration with the European Bioinformatics Institute, the MetabolomeXchange was launched as an international index of freely accessible metabolomics data from around the world. As of December 2015 nearly 300 datasets are now available at http://metabolomexchange.org/ Exit Disclaimer from three different repositories including the Common Fund Metabolomics Workbench. Exit Disclaimer


The NIH's Common Fund Metabolomics Program RCMRCs are soliciting applications for the 2016 Pilot and Feasibility Awards.   These awards are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research.  Read more here.

The Common Fund Metabolomics program solicits applications for small grants to foster collaboration between bioinformaticians and the metabolomics community.  These one year grants are to support bidirectional collaborations such that in-depth appreciation of both the biology and the informatics would promote the development of new or improved approaches to metabolomics data analysis.  The awards are also intended to complement the current efforts of the Common Fund Metabolomics Program and maximize the value of existing metabolomics databases and resources.  Click for more information.

The NIH's Common Fund has announced funding opportunities for the Molecular Transducers of Physical Activity in Humans program, including a call for metabolomic analysis.  Read more information about this program and the associated funding opportunities here.  

NEW!  The Common Fund Metabolomics program is soliciting applications for Administrative Supplements. The program aims to support multi-disciplinary research using metabolomics and to help investigators gain experience in metabolomics techniques. The administrative supplements would forge new collaborations between basic biomedical or clinical researchers and metabolomics experts for studies that fall within the scope of the parent grant, but require a metabolomics approach. Click for more information.

Studying Sex DifferencesMetabolomics Scientists Investigate Sex Differences. Sex and gender play a role in how health and disease differ across individuals, and considering these factors during research informs the development of preventive and therapeutic interventions for both sexes. Learn how supplements to Metabolomics grants are enabling researchers to investigate sex as a biological variable.

Online Learning Platform: Welcome to Metabolomics in Medicine. Developed by Martin Kohlmeier from the University of North Carolina. Online instruction and other resources at this site Exit Disclaimer will help researchers and clinicians to catch up with the rapid pace of development in the metabolomic sciences. The learning materials will teach the scientific foundations for understanding current technologies and analytical strategies. Supported by a NIH Common Fund Metabolomics Award (R25 GM103802).

Online Metabolomics Training and Education. A variety of metabolomics training and education resources are now available from members of the Metabolomics program consortium online at the Metabolomics Workbench. Training media include Tutorials, Videocasts, and Workshop Materials that span general metabolomics introductions to advanced metabolomics techniques and technologies. Browse the Online Metabolomics Training and Education Materials.  Exit Disclaimer

Learn more about the strengths of each NIH-funded metabolomics resource core hereExit Disclaimer

Nominations now being accepted for metabolite standards to be synthesized by the NIH’s Common Fund Metabolomics program. Read More . . . Exit Disclaimer



For Metabolomics Data and Resources visit the Metabolomics Workbench  Exit Disclaimer




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