We Accelerate Discovery

You are here

Printer

Program Snapshot

Metablomics Highlight

The NIH Common Fund’s Metabolomics program aims to increase national capacity in metabolomics by supporting the development of next generation technologies to enhance the sensitivity and speed with which specific elements of the cellular metabolome can be identified and quantified, providing training and mentoring opportunities, increasing the inventory of chemically identifiable metabolites through the synthesis and availability of high quality reference standards, and by promoting data sharing and collaboration. Learn more here

Program Highlights

Metabolomics Reveals New Cross-Talk between Tumors and Surrounding Cells. A team of researchers has recently collaborated with one of the NIH Common Fund’s Metabolomics Cores to uncover a new mechanism by which tumor cells obtain the nutrients they need to grow. Read more about this exciting research.


The Common Fund Supports Training in Metabolomics. Dr. Stephen Barnes and colleagues have published two recent papers describing the range of training offered at the Common Fund-supported workshop on metabolomics held annually at the University of Alabama at Birmingham. Learn more about these papers and the training they detail here.


Metabolomics Scientists Tie Metabolites to Lifespan in Mammals Research from a group including NIH Common Fund’s Metabolomics Program grantee Sun Hee Yim used the latest metabolomics techniques to look at a wide range of metabolites from 26 diverse species of mammals.  They were able to correlate the levels of specific metabolites with the range of lifespans that exists across the mammals sampled, providing insight into biological mechanisms of longevity. Read more about this research.


Features of the Metabolomics Workbench highlighted in a recent publication
A new publication highlights the Metabolomics Workbench, created by the Metabolomics Program’s Data Repository and Coordination Center, and describes how to access resources from the Metabolomics Program. For additional information and to read a brief description of the research article.


Taming the Torrent of Metabolic Data
Molecular structures of norcocaine and metoclopramide​Metabolomics Program grantee, Dr. Oliver Fiehn at the NIH West Coast Metabolomics Center at UC Davis, and his colleagues in Japan, have developed open source software called MS-DIAL to help researchers analyze their untargeted metabolomics data. Read a brief description of the research.


Learn more about the Metabolomics Community

 

The NIH Common Fund Metabolomics Program supports international data sharing through the MetabolomeXchange.

In April 2014, representatives from Australia, Canada, Germany, Japan, the Netherlands and the United States NIH Common Fund Metabolomics program met to discuss an international data exchange in metabolomics. The participants agreed to create a portal that would provide a network of coordinated and freely accessible metabolomics data collected from repositories around the world. As a result of this meeting and in collaboration with the European Bioinformatics Institute, the MetabolomeXchange was launched as an international index of freely accessible metabolomics data from around the world. As of August 2016 nearly 500 datasets are now available at http://metabolomexchange.org/ from three different repositories including the Common Fund Metabolomics Workbench.
MetabolomeXchange logo

 

New Funding Opportunity to Support Metabolomics Data Analysis.  The Metabolomics program has issued a funding opportunity announcement to foster collaboration between computational scientists, metabolomics experts, and biomedical researchers in developing, piloting, and/or validating novel bioinformatic approaches that address current analytical hurdles in metabolomics data. A goal of providing powerful approaches that will be useful to biomedical researchers, as well as bioinformaticians, is particularly encouraged. Projects are not intended to supplement ongoing metabolomics analyses, but to provide a tool for broader use by the biomedical research community. Projects are expected to use existing, publicly available metabolomics data and complement the efforts and resources of the Common Fund Metabolomics Program. Letters of intent are due January 14th 2017.  Applications are due February 14th 2017.  Learn more about the Funding Opportunity Announcement.  

Learn more about the NIH Metabolomics Scientific Interest Group! Visit the webpage to sign up for the listserv and get information on metabolomics-related seminars, funding opportunities, and other metabolomics resources.  Check back frequently for information on group sponsored webinars and other exciting content.    

The Michigan Regional Comprehensive Metabolomics Resource Core (MRC2) is presenting a four-day workshop from May 8-11, 2017.  This workshop is intended for investigators seeking a solid foundation to expand their research using metabolomics.  For more information about the fifth-annual MRC2 workshop, please visit their website.

Metabolomics Investigator Named a Rising Star by the American Chemical Society.  Dr. Erin Baker, a researcher supported by the Common Fund Metabolomics program, recently received one of six Rising Star awards from the Women Chemists Committee of the American Chemical Society.  Dr. Baker has used support from the Common Fund to develop and evaluate a new, high throughput metabolomics platform using ion mobility spectrometry in conjunction with mass spectrometry in order to analyze clinically relevant metabolomics samples with significantly improved sensitivity, coverage and throughput.  More information on Dr. Baker’s research and the Rising Star award can be found here.  Congratulations Dr. Baker!

Importance of Metabolomics to the Precision Medicine Initiative. A recent paper from the Precision Medicine and Pharmacometabolomics Task Group of the Metabolomics Society highlights how metabolomics can help support and enhance precision medicine efforts such as the NIH’s new PMI Cohort Program. While doctors currently only capture a small snapshot of a patient’s metabolic status using traditional methods, in depth metabolomics analyses can provide extensive information regarding an individual’s overall health status. The metabolomics community believes that by including more metabolic data in medical initiatives, we will gain better insight into disease progression, disease subtypes, and drug responsiveness. To read the entire report click here.

Online Learning Platform: Welcome to Metabolomics in Medicine. Developed by Martin Kohlmeier from the University of North Carolina. Online instruction and other resources at this site will help researchers and clinicians to catch up with the rapid pace of development in the metabolomic sciences. The learning materials will teach the scientific foundations for understanding current technologies and analytical strategies. Supported by a NIH Common Fund Metabolomics Award (R25 GM103802).

Online Metabolomics Training and Education. A variety of metabolomics training and education resources are now available from members of the Metabolomics program consortium online at the Metabolomics Workbench. Training media include Tutorials, Videocasts, and Workshop Materials that span general metabolomics introductions to advanced metabolomics techniques and technologies. Browse the Online Metabolomics Training and Education Materials.

Learn more about the strengths of each NIH-funded metabolomics resource core here!

Nominations now being accepted for metabolite standards to be synthesized by the NIH’s Common Fund Metabolomics program. Read More . . . 

 

 

For Metabolomics Data and Resources visit the Metabolomics Workbench 

Metabolomics Workbench Banner

 

 

 

Up to Top