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Program Snapshot

Metablomics Highlight

The NIH Common Fund’s Metabolomics program aims to increase national capacity in metabolomics by supporting the development of next generation technologies to enhance the sensitivity and speed with which specific elements of the cellular metabolome can be identified and quantified, providing training and mentoring opportunities, increasing the inventory of chemically identifiable metabolites through the synthesis and availability of high quality reference standards, and by promoting data sharing and collaboration. Learn more here

Program Highlights

Metabolomics Reveals New Cross-Talk between Tumors and Surrounding Cells. A team of researchers has recently collaborated with one of the NIH Common Fund’s Metabolomics Cores to uncover a new mechanism by which tumor cells obtain the nutrients they need to grow. Read more about this exciting research.

The Common Fund Supports Training in Metabolomics. Dr. Stephen Barnes and colleagues have published two recent papers describing the range of training offered at the Common Fund-supported workshop on metabolomics held annually at the University of Alabama at Birmingham. Learn more about these papers and the training they detail here.

Metabolomics Scientists Tie Metabolites to Lifespan in Mammals Research from a group including NIH Common Fund’s Metabolomics Program grantee Sun Hee Yim used the latest metabolomics techniques to look at a wide range of metabolites from 26 diverse species of mammals.  They were able to correlate the levels of specific metabolites with the range of lifespans that exists across the mammals sampled, providing insight into biological mechanisms of longevity. Read more about this research.

Features of the Metabolomics Workbench highlighted in a recent publication
A new publication highlights the Metabolomics Workbench, created by the Metabolomics Program’s Data Repository and Coordination Center, and describes how to access resources from the Metabolomics Program. For additional information and to read a brief description of the research article.

Taming the Torrent of Metabolic Data
Molecular structures of norcocaine and metoclopramide​Metabolomics Program grantee, Dr. Oliver Fiehn at the NIH West Coast Metabolomics Center at UC Davis, and his colleagues in Japan, have developed open source software called MS-DIAL to help researchers analyze their untargeted metabolomics data. Read a brief description of the research.

Learn more about the Metabolomics Community


The NIH Common Fund Metabolomics Program supports international data sharing through the MetabolomeXchange.

In April 2014, representatives from Australia, Canada, Germany, Japan, the Netherlands and the United States NIH Common Fund Metabolomics program met to discuss an international data exchange in metabolomics. The participants agreed to create a portal that would provide a network of coordinated and freely accessible metabolomics data collected from repositories around the world. As a result of this meeting and in collaboration with the European Bioinformatics Institute, the MetabolomeXchange was launched as an international index of freely accessible metabolomics data from around the world. As of August 2016 nearly 500 datasets are now available at http://metabolomexchange.org/ from three different repositories including the Common Fund Metabolomics Workbench.
MetabolomeXchange logo


Common Fund-Supported Scientists Develop Exhibit Highlighting Metabolomics Impact on Health. The Common Fund- supported Eastern Regional Comprehensive Metabolomics Resource Core at RTI International, in partnership with the North Carolina Museum of Natural Sciences, designed the “Meet your Metabolites” module, part of an exciting new fully-interactive museum exhibit called “The Secret World Inside You.”  Open through March 12, 2017, this exhibit uses larger-than-life-models to explore the evolving science that is revolutionizing how we view human health and understand the inner workings of the body. The “Meet your Metabolites” module describes how the study of metabolomics can be used to assess a person’s health and provide warning signs for certain diseases.

Metabolomics Investigator Named a Rising Star by the American Chemical Society.  Dr. Erin Baker, a researcher supported by the Common Fund Metabolomics program, recently received one of six Rising Star awards from the Women Chemists Committee of the American Chemical Society.  Dr. Baker has used support from the Common Fund to develop and evaluate a new, high throughput metabolomics platform using ion mobility spectrometry in conjunction with mass spectrometry in order to analyze clinically relevant metabolomics samples with significantly improved sensitivity, coverage and throughput.  More information on Dr. Baker’s research and the Rising Star award can be found here.  Congratulations Dr. Baker!

Importance of Metabolomics to the Precision Medicine Initiative. A recent paper from the Precision Medicine and Pharmacometabolomics Task Group of the Metabolomics Society highlights how metabolomics can help support and enhance precision medicine efforts such as the NIH’s new PMI Cohort Program. While doctors currently only capture a small snapshot of a patient’s metabolic status using traditional methods, in depth metabolomics analyses can provide extensive information regarding an individual’s overall health status. The metabolomics community believes that by including more metabolic data in medical initiatives, we will gain better insight into disease progression, disease subtypes, and drug responsiveness. To read the entire report click here.

NCI recently announced 15 new contract funding opportunities under the Small Business Innovation Research (SBIR) program including one for Methods and Software for Integration of Cancer Metabolomic Data with Other –Omic and Imaging Data.  More information about the SBIR Program Contract Solicitation can be found here.

Online Learning Platform: Welcome to Metabolomics in Medicine. Developed by Martin Kohlmeier from the University of North Carolina. Online instruction and other resources at this site will help researchers and clinicians to catch up with the rapid pace of development in the metabolomic sciences. The learning materials will teach the scientific foundations for understanding current technologies and analytical strategies. Supported by a NIH Common Fund Metabolomics Award (R25 GM103802).

Online Metabolomics Training and Education. A variety of metabolomics training and education resources are now available from members of the Metabolomics program consortium online at the Metabolomics Workbench. Training media include Tutorials, Videocasts, and Workshop Materials that span general metabolomics introductions to advanced metabolomics techniques and technologies. Browse the Online Metabolomics Training and Education Materials.

Learn more about the strengths of each NIH-funded metabolomics resource core here!

Nominations now being accepted for metabolite standards to be synthesized by the NIH’s Common Fund Metabolomics program. Read More . . . 



For Metabolomics Data and Resources visit the Metabolomics Workbench 

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