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Program Snapshot

The Common Fund's Epigenomics Program includes a series of complementary initiatives aimed at generating new research tools, technologies, datasets, and infrastructure to accelerate our understanding of how genome-wide chemical modifications to DNA regulate gene activity without altering the DNA sequence itself and what role these modifications play in health and disease.

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A Scientific Illustration of How Epigenetic Mechanisms Can Affect Health

 

Program Highlights

Precise Epigenetic Control of gene expression using CRISPR

Precise Epigenetic Control of Gene Expression Using CRISPR

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Common Fund-supported researchers map epigenome of more than 100 tissue and cell types

Uncovering Important Epigenetic Changes in Neuronal Cell Development

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Common Fund-supported researchers map epigenome of more than 100 tissue and cell types

Common Fund-Supported Researchers Develop Powerful Tools to Edit Genomes

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Common Fund-supported researchers map epigenome of more than 100 tissue and cell types

Common fund-supported researchers map epigenome of more than 100 tissue and cell types

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Multimedia

Watch Epigenomics grantee John Stamatoyannopoulos’ lecture “A Roadmap to the Living Genome,” in which he presents research describing new epigenomic maps for a wide variety of normal human cell/tissue types; insights into the genomic patterning of epigenomic features; and encoding of cellular state, maturity, and fate information within epigenomic landscapes.

Watch “A Roadmap to the Living Genome” video here.

Download slides from the Epigenomics presentation to the NIH Council of Councils

Download slides here.

NEW: "Epigenome debut" #10 Top Science Story of 2015.

Science News has ranked the Epigenomics program's "blockbuster effort" of cataloging chemical DNA modifications as the #10 most important science story of 2015. Read the full story here. Exit Disclaimer

NIH Roadmap Epigenomics

Information about the data, protocols, reagents, and analytical tools generated by the Epigenomics Program, including over 100 comprehensive reference epigenomic datasets from hundreds of human cell types and tissues, can be found on the Roadmap Epigenomics Website. Exit Disclaimer

Epigenomes Around the World

Epigenomes around the world: International Human Epigenome ConsortiumThe Epigenomics Program is part of the International Human Epigenome Consortium that aims to coordinate worldwide epigenome mapping and characterization efforts.

Read more about the IHEC... Exit Disclaimer​​

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