Single Cell Analysis
Many biological experiments are performed on groups of cells, under the assumption that all cells of a particular “type” are identical. However, recent evidence from studies of single cells reveals that this assumption is incorrect. Individual cells within the same population may differ dramatically, and these differences can have important consequences for the health and function of the entire population.
Cellular barcodes for single cell profiling
Dr. Christopher Love at the Massachusetts Institute of Technology and colleagues have developed techniques to label heterogeneous or homogeneous cells using “barcoding” (i.e. combinatorial application of dyes, streptavidin/biotin or antibody labels), sort the barcoded cells into small wells, and then characterize the cytokines (signaling molecules) produced by the cell(s) in each of the wells.
The dates for the next Single Cell meeting are tentatively set for April 21-22, 2014. More details this Winter.
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NEW! Funding Opportunity Announcement for Single Cell Analysis Program.
Development of Highly Innovative Tools and Technology for Analysis of Single Cells
This FOA is affiliated with the Common Fund Single Cell Analysis Program (SCAP), but is not receiving direct Common Fund support. Awards made through this FOA will be funded by participating component NIH Institutes and Centers.
The Common Fund’s new Single Cell Analysis program seeks to overcome current obstacles by focusing on opportunities in the following areas:
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