Regulatory Science (656)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus.Rosenthal, Eric S; Elm, Jordan J; Ingles, James; Rogers, Alexander J; Terndrup, Thomas E; Holsti, Maija; Thomas, Danny G; Babcock, Lynn; Okada, Pamela J; Lipsky, Robert H; Miller, Joseph B; Hickey, Robert W; Barra, Megan E; Bleck, Thomas P; Cloyd, James C; Silbergleit, Robert; Lowenstein, Daniel H; Coles, Lisa D; Kapur, Jaideep; Shinnar, Shlomo; Chamberlain, James M; Established Status Epilepticus Treatment Trial Study GroupNeurology2021 05 1134032604
Vascular endothelial cell specification in health and disease.Marziano, Corina; Genet, Gael; Hirschi, Karen KAngiogenesis2021 Apr 1233844116
Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers.Chen, Amanda X; Chhabra, Arnav; Song, H-H Greco; Fleming, Heather E; Chen, Christopher S; Bhatia, Sangeeta NAdvanced functional materials2020 Nov 2533776613
Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling.Mina, Sara G; Alaybeyoglu, Begum; Murphy, William L; Thomson, James A; Stokes, Cynthia L; Cirit, MuratFrontiers in big data201933693346
Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease.Lidberg, Kevin A; Annalora, Andrew J; Jozic, Marija; Elson, Daniel J; Wang, Lu; Bammler, Theo K; Ramm, Susanne; Monteiro, Maria Beatriz; Himmelfarb, Jonathan; Marcus, Craig B; Iversen, Patrick L; Kelly, Edward JScientific reports2021 Feb 2533633318
Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues.Song, H-H Greco; Lammers, Alex; Sundaram, Subramanian; Rubio, Logan; Chen, Amanda X; Li, Linqing; Eyckmans, Jeroen; Bhatia, Sangeeta N; Chen, Christopher SAdvanced functional materials2020 Nov 2533613149
An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy.Hachey, Stephanie J; Movsesyan, Silva; Nguyen, Quy H; Burton-Sojo, Giselle; Tankazyan, Ani; Wu, Jie; Hoang, Tuyen; Zhao, Da; Wang, Shuxiong; Hatch, Michaela M; Celaya, Elizabeth; Gomez, Samantha; Chen, George T; Davis, Ryan T; Nee, Kevin; Pervolarakis, Nicholas; Lawson, Devon A; Kessenbrock, Kai; Lee, Abraham P; Lowengrub, John; Waterman, Marian L; Hughes, Christopher C WLab on a chip2021 04 0733605955
Modeling the Complexity of the Metastatic Niche Ex Vivo.Clark, Amanda MMethods in molecular biology (Clifton, N.J.)202133340364
Electroencephalographic Seizures in Emergency Department Patients After Treatment for Convulsive Status Epilepticus.Zehtabchi, Shahriar; Silbergleit, Robert; Chamberlain, James M; Shinnar, Shlomo; Elm, Jordan J; Underwood, Ellen; Rosenthal, Eric S; Bleck, Thomas P; Kapur, JaideepJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2020 Dec 1133337664
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification.Qiu, Jingyao; Nordling, Sofia; Vasavada, Hema H; Butcher, Eugene C; Hirschi, Karen KCell reports2020 Dec 0133264627
Modeling statin myopathy in a human skeletal muscle microphysiological system.Ananthakumar, Anandita; Liu, Yiling; Fernandez, Cristina E; Truskey, George A; Voora, DeepakPloS one202033237943
Extra Cellular Matrix-Based and Extra Cellular Matrix-Free Generation of Murine Testicular Organoids.Edmonds, Maxwell E; Forshee, Micah D; Woodruff, Teresa KJournal of visualized experiments : JoVE.2020 10 07;33104061
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip.Yadid, Moran; Lind, Johan U; Ardoña, Herdeline Ann M; Sheehy, Sean P; Dickinson, Lauren E; Eweje, Feyisayo; Bastings, Maartje M C; Pope, Benjamin; O'Connor, Blakely B; Straubhaar, Juerg R; Budnik, Bogdan; Kleber, Andre G; Parker, Kevin KitScience translational medicine2020 10 1433055246
A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer.Korentzelos, Dimitrios; Clark, Amanda M; Wells, AlanInternational journal of molecular sciences.2020 Oct 03;33022920
Isolation of Highly Purified and Viable Retinal Endothelial Cells.Chavkin, Nicholas W; Walsh, Kenneth; Hirschi, Karen KJournal of vascular research202133022674
Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs.Liu, Yizhong; Sakolish, Courtney; Chen, Zunwei; Phan, Duc T T; Bender, R Hugh F; Hughes, Christopher C W; Rusyn, IvanToxicology.2020 Dec 01;32980478
Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety.Chramiec, Alan; Teles, Diogo; Yeager, Keith; Marturano-Kruik, Alessandro; Pak, Joseph; Chen, Timothy; Hao, Luke; Wang, Miranda; Lock, Roberta; Tavakol, Daniel Naveed; Lee, Marcus Busub; Kim, Jinho; Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, GordanaLab on a chip2020 11 2432955072
Continuous Formation of Ultrathin, Strong Collagen Sheets with Tunable Anisotropy and Compaction.Malladi, Shashi; Miranda-Nieves, David; Leng, Lian; Grainger, Stephanie J; Tarabanis, Constantine; Nesmith, Alexander P; Kosaraju, Revanth; Haller, Carolyn A; Parker, Kevin Kit; Chaikof, Elliot L; Günther, AxelACS biomaterials science & engineering2020 07 1332685675
Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes.Bhatraju, Pavan K; Cohen, Max; Nagao, Ryan J; Morrell, Eric D; Kosamo, Susanna; Chai, Xin-Ya; Nance, Robin; Dmyterko, Victoria; Delaney, Joseph; Christie, Jason D; Liu, Kathleen D; Mikacenic, Carmen; Gharib, Sina A; Liles, W Conrad; Zheng, Ying; Christiani, David C; Himmelfarb, Jonathan; Wurfel, Mark MBMC nephrology2020 07 1732680471
Distinct follicular and luteal transcriptional profiles in engineered human ectocervical tissue dependent on menstrual cycle phase.McKinnon, Kelly E; Getsios, Spiro; Woodruff, Teresa KBiology of reproduction2020 08 2132614039
Integrative microphysiological tissue systems of cancer metastasis to the liver.Clark, Amanda M; Allbritton, Nancy L; Wells, AlanSeminars in cancer biology.2020 Jun 21;32580025
Testicular organoid formation is a property of immature somatic cells, which self-assemble and exhibit long-term hormone-responsive endocrine function.Edmonds, Maxwell E; Woodruff, Teresa KBiofabrication.2020 07 09;32492667
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection.Foulke-Abel, Jennifer; Yu, Huimin; Sunuwar, Laxmi; Lin, Ruxian; Fleckenstein, James M; Kaper, James B; Donowitz, MarkGut microbes.2020 May 07;32378997
Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers.Khodabukus, Alastair; Kaza, Amulya; Wang, Jason; Prabhu, Neel; Goldstein, Richard; Vaidya, Vishal S; Bursac, NenadToxicological sciences : an official journal of the Society of Toxicology.2020 Jul 01;32294208
Engineered reproductive tissues.Gargus, Emma S; Rogers, Hunter B; McKinnon, Kelly E; Edmonds, Maxwell E; Woodruff, Teresa KNature biomedical engineering.2020 04;32251392
Applications of the microphysiology systems database for experimental ADME-Tox and disease models.Schurdak, Mark; Vernetti, Lawrence; Bergenthal, Luke; Wolter, Quinn K; Shun, Tong Ying; Karcher, Sandra; Taylor, D Lansing; Gough, AlbertLab on a chip.2020 Apr 14;32211684
Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial.Chamberlain, James M; Kapur, Jaideep; Shinnar, Shlomo; Elm, Jordan; Holsti, Maija; Babcock, Lynn; Rogers, Alex; Barsan, William; Cloyd, James; Lowenstein, Daniel; Bleck, Thomas P; Conwit, Robin; Meinzer, Caitlyn; Cock, Hannah; Fountain, Nathan B; UnderwooLancet (London, England).2020 04 11;32203691
Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle.Kondash, Megan E; Ananthakumar, Anandita; Khodabukus, Alastair; Bursac, Nenad; Truskey, George ATissue engineering and regenerative medicine.2020 Mar 21;32200516
Machine learning to predict developmental neurotoxicity with high-throughput data from 2D bio-engineered tissues.Kuusisto, Finn; Costa, Vitor Santos; Hou, Zhonggang; Thomson, James; Page, David; Stewart, RonProceedings of the ... International Conference on Machine Learning and Applications. International Conference on Machine Learning and Applications.2019 Dec;32181450
TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes.Jiang, Peng; Chamberlain, Connie S; Vanderby, Ray; Thomson, James A; Stewart, RonNucleic acids research.2020 05 21;32123905
Maladaptive Contractility of 3D Human Cardiac Microtissues to Mechanical Nonuniformity.Wang, Chenyan; Koo, Sangmo; Park, Minok; Vangelatos, Zacharias; Hoang, Plansky; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin E; Ma, ZhenAdvanced healthcare materials.2020 Apr;32090507
Perspectives on In Vitro to In Vivo Extrapolations.Hartung, ThomasApplied in vitro toxicology.2018 Dec 01;31890748
Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling.Sakolish, Courtney; Chen, Zunwei; Dalaijamts, Chimeddulam; Mitra, Kusumica; Liu, Yina; Fulton, Tracy; Wade, Terry L; Kelly, Edward J; Rusyn, Ivan; Chiu, Weihsueh AToxicology in vitro : an international journal published in association with BIBRA.2020 Mar;31857146
Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer.Ma, Bo; Khazali, Ahmad; Shao, Hanshuang; Jiang, Yuhan; Wells, AlanCell communication and signaling : CCS.2019 Dec 12;31831069
Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics.Barry, Christopher; Schmitz, Matthew T; Argus, Cara; Bolin, Jennifer M; Probasco, Mitchell D; Leng, Ning; Duffin, Bret M; Steill, John; Swanson, Scott; McIntosh, Brian E; Stewart, Ron; Kendziorski, Christina; Thomson, James A; Bacher, RhondaPLoS computational biology.2019 12;31815944
Human Induced Pluripotent Stem-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anticancer Efficacy and Cardiotoxicity.Weng, Kuo-Chan; Kurokawa, Yosuke K; Hajek, Brianna S; Paladin, Jack A; Shirure, Venktesh S; George, Steven CTissue engineering. Part C, Methods.2020 Jan;31797733
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.Kapur, Jaideep; Elm, Jordan; Chamberlain, James M; Barsan, William; Cloyd, James; Lowenstein, Daniel; Shinnar, Shlomo; Conwit, Robin; Meinzer, Caitlyn; Cock, Hannah; Fountain, Nathan; Connor, Jason T; Silbergleit, Robert; NETT and PECARN InvestigatorsThe New England journal of medicine.2019 11 28;31774955
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence.Garbern, Jessica C; Helman, Aharon; Sereda, Rebecca; Sarikhani, Mohsen; Ahmed, Aishah; Escalante, Gabriela O; Ogurlu, Roza; Kim, Sean L; Zimmerman, John F; Cho, Alexander; MacQueen, Luke; Bezzerides, Vassilios J; Parker, Kevin Kit; Melton, Douglas A; Lee,Circulation.2020 01 28;31707831
Lessons from the Established Status Epilepticus Treatment Trial.Cock, Hannah R; Coles, Lisa D; Elm, Jordan; Silbergleit, Robert; Chamberlain, James M; Cloyd, James C; Fountain, Nathan; Shinnar, Shlomo; Lowenstein, Dan; Conwit, Robin; Bleck, Thomas P; Kapur, JaideepEpilepsy & behavior : E&B.2019 Dec;31653603
Endothelial Cell Development and Its Application to Regenerative Medicine.Qiu, Jingyao; Hirschi, Karen KCirculation research2019 08 0231518171
Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype.Ronaldson-Bouchard, Kacey; Yeager, Keith; Teles, Diogo; Chen, Timothy; Ma, Stephen; Song, LouJin; Morikawa, Kumi; Wobma, Holly M; Vasciaveo, Alessandro; Ruiz, Edward C; Yazawa, Masayuki; Vunjak-Novakovic, GordanaNature protocols.2019 10;31492957
A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling.Nguyen, Duc-Huy T; Lee, Esak; Alimperti, Styliani; Norgard, Robert J; Wong, Alec; Lee, Jake June-Koo; Eyckmans, Jeroen; Stanger, Ben Z; Chen, Christopher SScience advances.2019 Aug;31489365
An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells.Chu, Li-Fang; Mamott, Daniel; Ni, Zijian; Bacher, Rhonda; Liu, Cathy; Swanson, Scott; Kendziorski, Christina; Stewart, Ron; Thomson, James ACell reports.2019 Aug 27;31461642
Engineered skeletal muscles for disease modeling and drug discovery.Wang, Jason; Khodabukus, Alastair; Rao, Lingjun; Vandusen, Keith; Abutaleb, Nadia; Bursac, NenadBiomaterials.2019 Nov;31419653
The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment.Ma, Bo; Wells, Alan; Clark, Amanda MSeminars in cancer biology.2019 Jul 31;31376430
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.Argemi, Josepmaria; Latasa, Maria U; Atkinson, Stephen R; Blokhin, Ilya O; Massey, Veronica; Gue, Joel P; Cabezas, Joaquin; Lozano, Juan J; Van Booven, Derek; Bell, Aaron; Cao, Sheng; Vernetti, Lawrence A; Arab, Juan P; Ventura-Cots, Meritxell; Edmunds, Lia R; Fondevilla, Constantino; Stärkel, Peter; Dubuquoy, Laurent; Louvet, Alexandre; Odena, Gemma; Gomez, Juan L; Aragon, Tomas; Altamirano, Jose; Caballeria, Juan; Jurczak, Michael J; Taylor, D Lansing; Berasain, Carmen; Wahlestedt, Claes; Monga, Satdarshan P; Morgan, Marsha Y; Sancho-Bru, Pau; Mathurin, Philippe; Furuya, Shinji; Lackner, Carolin; Rusyn, Ivan; Shah, Vijay H; Thursz, Mark R; Mann, Jelena; Avila, Matias A; Bataller, RamonNature communications.2019 Jul 16;31311938
Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue.Park, Sung-Jin; Zhang, Donghui; Qi, Yan; Li, Yifei; Lee, Keel Yong; Bezzerides, Vassilios J; Yang, Pengcheng; Xia, Shutao; Kim, Sean L; Liu, Xujie; Lu, Fujian; Pasqualini, Francesco S; Campbell, Patrick H; Geva, Judith; Roberts, Amy E; Kleber, Andre G; Abrams, Dominic J; Pu, William T; Parker, Kevin KitCirculation.2019 Jul 30;31311300
Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions.Davis, Brittany N; Yen, Ringo; Prasad, Varun; Truskey, George AAPL bioengineering.2019 Jun;31149650
A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia.Zhang, Jue; McIntosh, Brian E; Wang, Bowen; Brown, Matthew E; Probasco, Mitchell D; Webster, Sarah; Duffin, Bret; Zhou, Ying; Guo, Lian-Wang; Burlingham, William J; Kent, Craig; Ferris, Michael; Thomson, James AStem cell reports.2019 Jun 11;31080110
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload.Ma, Zhen; Huebsch, Nathaniel; Koo, Sangmo; Mandegar, Mohammad A; Siemons, Brian; Boggess, Steven; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin ENature biomedical engineering.2018 12;31015724
A tissue-engineered scale model of the heart ventricle.MacQueen, Luke A; Sheehy, Sean P; Chantre, Christophe O; Zimmerman, John F; Pasqualini, Francesco S; Liu, Xujie; Goss, Josue A; Campbell, Patrick H; Gonzalez, Grant M; Park, Sung-Jin; Capulli, Andrew K; Ferrier, John P; Kosar, T Fettah; Mahadevan, L; Pu, William T; Parker, Kevin KitNature biomedical engineering.2018 12;31015723
Modeling the Effect of TNF-? upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles.Davis, Brittany N J; Santoso, Jeffrey W; Walker, Michaela J; Oliver, Catherine E; Cunningham, Michael M; Boehm, Christian A; Dawes, Danielle; Lasater, Samantha L; Huffman, Kim; Kraus, William E; Truskey, George AAnnals of biomedical engineering.2019 Jul;30963383
Microfabricated blood vessels for modeling the vascular transport barrier.Polacheck, William J; Kutys, Matthew L; Tefft, Juliann B; Chen, Christopher SNature protocols.2019 05;30953042
Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System.Maass, Christian; Sorensen, Nathan B; Himmelfarb, Jonathan; Kelly, Edward J; Stokes, Cynthia L; Cirit, MuratCPT: pharmacometrics & systems pharmacology.2019 05;30869201
cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.Tse, Chung-Ming; Yin, Jianyi; Singh, Varsha; Sarker, Rafiquel; Lin, Ruxian; Verkman, Alan S; Turner, Jerrold R; Donowitz, MarkCellular and molecular gastroenterology and hepatology.2019;30659943
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro.Ramm, Susanne; Todorov, Petar; Chandrasekaran, Vidya; Dohlman, Anders; Monteiro, Maria B; Pavkovic, Mira; Muhlich, Jeremy; Shankaran, Harish; Chen, William W; Mettetal, Jerome T; Vaidya, Vishal SToxicological sciences : an official journal of the Society of Toxicology.2019 05 01;30649541
Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres.Abreu, Celina Monteiro; Gama, Lucio; Krasemann, Susanne; Chesnut, Megan; Odwin-Dacosta, Shelly; Hogberg, Helena T; Hartung, Thomas; Pamies, DavidFrontiers in microbiology.2018;30619100
A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis.Natividad-Diaz, Sylvia L; Browne, Shane; Jha, Amit K; Ma, Zhen; Hossainy, Samir; Kurokawa, Yosuke K; George, Steven C; Healy, Kevin EBiomaterials.2019 Feb;30583150
Microfluidic device to attain high spatial and temporal control of oxygen.Lam, Sandra F; Shirure, Venktesh S; Chu, Yunli E; Soetikno, Alan G; George, Steven CPloS one.2018;30571786
Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity.Weber, Elijah J; Lidberg, Kevin A; Wang, Lu; Bammler, Theo K; MacDonald, James W; Li, Mavis J; Redhair, Michelle; Atkins, William M; Tran, Cecilia; Hines, Kelly M; Herron, Josi; Xu, Libin; Monteiro, Maria Beatriz; Ramm, Susanne; Vaidya, Vishal; Vaara, Martti; Vaara, Timo; Himmelfarb, Jonathan; Kelly, Edward JJCI insight.2018 12 20;30568031
Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.Kaushik, Gaurav; Gil, Daniel A; Torr, Elizabeth; Berge, Elizabeth S; Soref, Cheryl; Uhl, Peyton; Fontana, Gianluca; Antosiewicz-Bourget, Jessica; Edington, Collin; Schwartz, Michael P; Griffith, Linda G; Thomson, James A; Skala, Melissa C; Daly, William T; Murphy, William LAdvanced healthcare materials.2019 01;30565891
Tissue engineering of human hair follicles using a biomimetic developmental approach.Abaci, Hasan Erbil; Coffman, Abigail; Doucet, Yanne; Chen, James; Jacków, Joanna; Wang, Etienne; Guo, Zongyou; Shin, Jung U; Jahoda, Colin A; Christiano, Angela MNature communications.2018 12 13;30546011
Engineering a Bioartificial Human Colon Model Through Decellularization and Recellularization.Chen, Huanhuan Joyce; Shuler, Michael LMethods in molecular biology (Clifton, N.J.).2019;30542993
Engineered 3D Microvascular Networks for the Study of Ultrasound-Microbubble-Mediated Drug Delivery.Juang, Eric K; De Cock, Ine; Keravnou, Christina; Gallagher, Madison K; Keller, Sara B; Zheng, Ying; Averkiou, MichalakisLangmuir : the ACS journal of surfaces and colloids.2019 08 06;30540481
Statin drugs to reduce breast cancer recurrence and mortality.Beckwitt, Colin H; Brufsky, Adam; Oltvai, Zoltán N; Wells, AlanBreast cancer research : BCR.2018 11 20;30458856
In vitro Models of Ischemia-Reperfusion Injury.Chen, Timothy; Vunjak-Novakovic, GordanaRegenerative engineering and translational medicine.2018 Sep;30393757
Reconstructing the Human Renal Vascular-Tubular Unit In Vitro.Rayner, Samuel G; Phong, Kiet T; Xue, Jun; Lih, Daniel; Shankland, Stuart J; Kelly, Edward J; Himmelfarb, Jonathan; Zheng, YingAdvanced healthcare materials.2018 12;30379416
Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel.Hiraki, Harrison L; Nagao, Ryan J; Himmelfarb, Jonathan; Zheng, YingJournal of visualized experiments : JoVE.2018 10 13;30371659
A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation.Monteiro, Maria B; Ramm, Susanne; Chandrasekaran, Vidya; Boswell, Sarah A; Weber, Elijah J; Lidberg, Kevin A; Kelly, Edward J; Vaidya, Vishal SJournal of the American Society of Nephrology : JASN.2018 12;30361326
Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments.Bacher, Rhonda; Leng, Ning; Chu, Li-Fang; Ni, Zijian; Thomson, James A; Kendziorski, Christina; Stewart, RonBMC bioinformatics.2018 Oct 16;30326833
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.Sakolish, Courtney; Weber, Elijah J; Kelly, Edward J; Himmelfarb, Jonathan; Mouneimne, Roula; Grimm, Fabian A; House, John S; Wade, Terry; Han, Arum; Chiu, Weihsueh A; Rusyn, IvanScientific reports.2018 10 05;30291268
Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells.Liu, Bohao; Lee, Benjamin W; Nakanishi, Koki; Villasante, Aranzazu; Williamson, Rebecca; Metz, Jordan; Kim, Jinho; Kanai, Mariko; Bi, Lynn; Brown, Kristy; Di Paolo, Gilbert; Homma, Shunichi; Sims, Peter A; Topkara, Veli K; Vunjak-Novakovic, GordanaNature biomedical engineering.2018 May;30271672
Human Organ-Specific Endothelial Cell Heterogeneity.Marcu, Raluca; Choi, Yoon Jung; Xue, Jun; Fortin, Chelsea L; Wang, Yuliang; Nagao, Ryan J; Xu, Jin; MacDonald, James W; Bammler, Theo K; Murry, Charles E; Muczynski, Kimberly; Stevens, Kelly R; Himmelfarb, Jonathan; Schwartz, Stephen M; Zheng, YingiScience.2018 Jun 29;30240741
Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle.Khodabukus, Alastair; Madden, Lauran; Prabhu, Neel K; Koves, Timothy R; Jackman, Christopher P; Muoio, Deborah M; Bursac, NenadBiomaterials.2019 Apr;30180985
Applications of tumor chip technology.Hachey, Stephanie J; Hughes, Christopher C WLab on a chip.2018 09 26;30156248
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.Oleaga, Carlota; Riu, Anne; Rothemund, Sandra; Lavado, Andrea; McAleer, Christopher W; Long, Christopher J; Persaud, Keisha; Narasimhan, Narasimhan Sriram; Tran, My; Roles, Jeffry; Carmona-Moran, Carlos A; Sasserath, Trevor; Elbrecht, Daniel H; Kumanchik, Lee; Bridges, L Richard; Martin, Candace; Schnepper, Mark T; Ekman, Gail; Jackson, Max; Wang, Ying I; Note, Reine; Langer, Jessica; Teissier, Silvia; Hickman, James JBiomaterials.2018 11;30130706
A system to monitor statin-induced myopathy in individual engineered skeletal muscle myobundles.Zhang, Xu; Hong, Sungmin; Yen, Ringo; Kondash, Megan; Fernandez, Cristina E; Truskey, George ALab on a chip.2018 09 11;30112530
Customizable biomaterials as tools for advanced anti-angiogenic drug discovery.Nguyen, Eric H; Murphy, William LBiomaterials.2018 10;30077137
Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.Bajaj, Piyush; Chowdhury, Swapan K; Yucha, Robert; Kelly, Edward J; Xiao, GuangqingDrug metabolism and disposition: the biological fate of chemicals.2018 11;30076203
Production and transplantation of bioengineered lung into a large-animal model.Nichols, Joan E; La Francesca, Saverio; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Frank, Luba; Christiani, David C; Pyles, Richard B; Himes, Blanca E; Zhang, Ruyang; Li, Su; Sakamoto, Jason; Rhudy, Jessica; Hendricks, Greg; Begarani, Filippo; Liu, Xuewu; Patrikeev, Igor; Pal, Rahul; Usheva, Emiliya; Vargas, Grace; Miller, Aaron; Woodson, Lee; Wacher, Adam; Grimaldo, Maria; Weaver, Daniil; Mlcak, Ron; Cortiella, JoaquinScience translational medicine.2018 08 01;30068570
A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX.Li, Xiang; George, Subin M; Vernetti, Lawrence; Gough, Albert H; Taylor, D LansingLab on a chip.2018 08 21;30063238
Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics.Ishikawa, Takuro; Hosaka, Yoshinao Z; Beckwitt, Colin; Wells, Alan; Oltvai, Zoltán N; Warita, KatsuhikoOncotarget.2018 Jun 29;30034619
Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images.Urban, Gregor; Bache, Kevin M; Phan, Duc; Sobrino, Agua; Shmakov, Alexander Konstantinovich; Hachey, Stephanie J; Hughes, Chris; Baldi, PierreIEEE/ACM transactions on computational biology and bioinformatics.2019 May-Jun;29993583
Mesangial cells, specialized renal pericytes and cytomegalovirus infectivity: Implications for HCMV pathology in the glomerular vascular unit and post-transplant renal disease.Popik, Waldemar; Correa, Hernan; Khatua, Atanu; Aronoff, David M; Alcendor, Donald JJournal of translational science.2019 Feb;29977613
Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers.Yin, Jianyi; Tse, Chung-Ming; Avula, Leela Rani; Singh, Varsha; Foulke-Abel, Jennifer; de Jonge, Hugo R; Donowitz, MarkCellular and molecular gastroenterology and hepatology.2018;29930980
Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel.Chen, Z; Tang, M; Huang, D; Jiang, W; Li, M; Ji, H; Park, J; Xu, B; Atchison, L J; Truskey, G A; Leong, K WLab on a chip.2018 07 10;29927449
Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.Adamski, Michal; Fontana, Gianluca; Gershlak, Joshua R; Gaudette, Glenn R; Le, Hau D; Murphy, William LJournal of visualized experiments : JoVE.2018 05 31;29912197
A pumpless body-on-a-chip model using a primary culture of human intestinal cells and a 3D culture of liver cells.Chen, Huanhuan Joyce; Miller, Paula; Shuler, Michael LLab on a chip.2018 07 10;29881844
Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies.Maass, Christian; Dallas, Matthew; LaBarge, Matthew E; Shockley, Michael; Valdez, Jorge; Geishecker, Emily; Stokes, Cynthia L; Griffith, Linda G; Cirit, MuratScientific reports.2018 May 22;29789564
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.Czerniecki, Stefan M; Cruz, Nelly M; Harder, Jennifer L; Menon, Rajasree; Annis, James; Otto, Edgar A; Gulieva, Ramila E; Islas, Laura V; Kim, Yong Kyun; Tran, Linh M; Martins, Timothy J; Pippin, Jeffrey W; Fu, Hongxia; Kretzler, Matthias; Shankland, Stuart J; Himmelfarb, Jonathan; Moon, Randall T; Paragas, Neal; Freedman, Benjamin SCell stem cell.2018 Jun 01;29779890
Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.Beckwitt, Colin H; Shiraha, Keisuke; Wells, AlanPloS one.2018;29763460
A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis.Miller, Chris P; Tsuchida, Connor; Zheng, Ying; Himmelfarb, Jonathan; Akilesh, ShreeramNeoplasia (New York, N.Y.).2018 06;29747161
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors.Thakore, Pratiksha I; Kwon, Jennifer B; Nelson, Christopher E; Rouse, Douglas C; Gemberling, Matthew P; Oliver, Matthew L; Gersbach, Charles ANature communications.2018 Apr 26;29700298
In Vitro Tissue-Engineered Skeletal Muscle Models for Studying Muscle Physiology and Disease.Khodabukus, Alastair; Prabhu, Neel; Wang, Jason; Bursac, NenadAdvanced healthcare materials.2018 08;29696831
Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.Wang, Hong-Xia; Song, Ziyuan; Lao, Yeh-Hsing; Xu, Xin; Gong, Jing; Cheng, Du; Chakraborty, Syandan; Park, Ji Sun; Li, Mingqiang; Huang, Dantong; Yin, Lichen; Cheng, Jianjun; Leong, Kam WProceedings of the National Academy of Sciences of the United States of America.2018 May 08;29686087
3S - Systematic, systemic, and systems biology and toxicology.Smirnova, Lena; Kleinstreuer, Nicole; Corvi, Raffaella; Levchenko, Andre; Fitzpatrick, Suzanne C; Hartung, ThomasALTEX.2018;29677694
Engineered Human Gastrointestinal Cultures to Study the Microbiome and Infectious Diseases.Blutt, Sarah E; Crawford, Sue E; Ramani, Sasirekha; Zou, Winnie Y; Estes, Mary KCellular and molecular gastroenterology and hepatology.2018 Mar;29675450
Quantitatively characterizing drug-induced arrhythmic contractile motions of human stem cell-derived cardiomyocytes.Hoang, Plansky; Huebsch, Nathaniel; Bang, Shin Hyuk; Siemons, Brian A; Conklin, Bruce R; Healy, Kevin E; Ma, Zhen; Jacquir, SabirBiotechnology and bioengineering.2018 08;29663322
Human organoid cultures: transformative new tools for human virus studies.Ramani, Sasirekha; Crawford, Sue E; Blutt, Sarah E; Estes, Mary KCurrent opinion in virology.2018 Apr;29656244
Advanced maturation of human cardiac tissue grown from pluripotent stem cells.Ronaldson-Bouchard, Kacey; Ma, Stephen P; Yeager, Keith; Chen, Timothy; Song, LouJin; Sirabella, Dario; Morikawa, Kumi; Teles, Diogo; Yazawa, Masayuki; Vunjak-Novakovic, GordanaNature.2018 Apr;29618819
Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment.Kotha, Surya; Sun, Sijie; Adams, Amie; Hayes, Brian; Phong, Kiet T; Nagao, Ryan; Reems, Jo-Anna; Gao, Dayong; Torok-Storb, Beverly; López, José A; Zheng, YingPloS one.2018;29617409
Multifaceted Roles of Connexin 43 in Stem Cell Niches.Genet, Nafiisha; Bhatt, Neha; Bourdieu, Antonin; Hirschi, Karen KCurrent stem cell reports.2018;29600160
Traction force microscopy of engineered cardiac tissues.Pasqualini, Francesco Silvio; Agarwal, Ashutosh; O'Connor, Blakely Bussie; Liu, Qihan; Sheehy, Sean P; Parker, Kevin KitPloS one.2018;29590169
Generation of spatial-patterned early-developing cardiac organoids using human pluripotent stem cells.Hoang, Plansky; Wang, Jason; Conklin, Bruce R; Healy, Kevin E; Ma, ZhenNature protocols.2018 Apr;29543795
Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development.Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, GordanaCell stem cell.2018 03 01;29499151
Multidrug Resistance Protein 1 Deficiency Promotes Doxorubicin-Induced Ovarian Toxicity in Female Mice.Wang, Yingzheng; Liu, Mingjun; Zhang, Jiyang; Liu, Yuwen; Kopp, Megan; Zheng, Weiwei; Xiao, ShuoToxicological sciences : an official journal of the Society of Toxicology.2018 May 01;29462422
Rotenone exerts developmental neurotoxicity in a human brain spheroid model.Pamies, David; Block, Katharina; Lau, Pierre; Gribaldo, Laura; Pardo, Carlos A; Barreras, Paula; Smirnova, Lena; Wiersma, Daphne; Zhao, Liang; Harris, Georgina; Hartung, Thomas; Hogberg, Helena TToxicology and applied pharmacology.2018 09 01;29428530
Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues.Karolak, Aleksandra; Markov, Dmitry A; McCawley, Lisa J; Rejniak, Katarzyna AJournal of the Royal Society, Interface.2018 Jan;29367239
The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms.Kang, Inhae; Chu, Charleen T; Kaufman, Brett AFEBS letters.2018 Mar;29364506
Human bone perivascular niche-on-a-chip for studying metastatic colonization.Marturano-Kruik, Alessandro; Nava, Michele Maria; Yeager, Keith; Chramiec, Alan; Hao, Luke; Robinson, Samuel; Guo, Edward; Raimondi, Manuela Teresa; Vunjak-Novakovic, GordanaProceedings of the National Academy of Sciences of the United States of America.2018 Feb 06;29363599
A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures.Clark, Amanda M; Kumar, Manu P; Wheeler, Sarah E; Young, Carissa L; Venkataramanan, Raman; Stolz, Donna B; Griffith, Linda G; Lauffenburger, Douglas A; Wells, AlanMolecular & cellular proteomics : MCP.2018 Apr;29353230
Automated fabrication of photopatterned gelatin hydrogels for organ-on-chips applications.Nawroth, Janna C; Scudder, Lisa L; Halvorson, Ryan T; Tresback, Jason; Ferrier, John P; Sheehy, Sean P; Cho, Alex; Kannan, Suraj; Sunyovszki, Ilona; Goss, Josue A; Campbell, Patrick H; Parker, Kevin KitBiofabrication.2018 Jan 16;29337695
Engineering human pluripotent stem cells into a functional skeletal muscle tissue.Rao, Lingjun; Qian, Ying; Khodabukus, Alastair; Ribar, Thomas; Bursac, NenadNature communications.;29317646
Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.Jia, Shanhang; Miedel, Mark T; Ngo, Marilyn; Hessenius, Ryan; Chen, Ning; Wang, Peilu; Bahreini, Amir; Li, Zheqi; Ding, Zhijie; Shun, Tong Ying; Zuckerman, Daniel M; Taylor, D Lansing; Puhalla, Shannon L; Lee, Adrian V; Oesterreich, Steffi; Stern, Andrew MOncology.2018 Jan 06;29306943
Liver 'organ on a chip'.Beckwitt, Colin H; Clark, Amanda M; Wheeler, Sarah; Taylor, D Lansing; Stolz, Donna B; Griffith, Linda; Wells, AlanExperimental cell research.2018 02 01;29291400
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Fang, Jennifer S; Coon, Brian G; Gillis, Noelle; Chen, Zehua; Qiu, Jingyao; Chittenden, Thomas W; Burt, Janis M; Schwartz, Martin A; Hirschi, Karen KNature communications.2017 12 15;29247167
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.Chang, Shih-Yu; Weber, Elijah J; Sidorenko, Viktoriya S; Chapron, Alenka; Yeung, Catherine K; Gao, Chunying; Mao, Qingcheng; Shen, Danny; Wang, Joanne; Rosenquist, Thomas A; Dickman, Kathleen G; Neumann, Thomas; Grollman, Arthur P; Kelly, Edward J; HimmelJCI insight.2017 Nov 16;29202460
Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy.Khazali, Ahmad S; Clark, Amanda M; Wells, AlanBritish journal of cancer.2018 Feb 20;29169181
A non-canonical Notch complex regulates adherens junctions and vascular barrier function.Polacheck, William J; Kutys, Matthew L; Yang, Jinling; Eyckmans, Jeroen; Wu, Yinyu; Vasavada, Hema; Hirschi, Karen K; Chen, Christopher SNature.2017 12 14;29160307
Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma.Villasante, A; Sakaguchi, K; Kim, J; Cheung, N K; Nakayama, M; Parsa, H; Okano, T; Shimizu, T; Vunjak-Novakovic, GTheranostics.2017;29158813
Executive summary of the 12th HHT international scientific conference.Andrejecsk, Jillian W; Hosman, Anna E; Botella, Luisa M; Shovlin, Claire L; Arthur, Helen M; Dupuis-Girod, Sophie; Buscarini, Elisabetta; Hughes, Christopher C W; Lebrin, Franck; Mummery, Christine L; Post, Marco C; Mager, Johannes JAngiogenesis2018 0229147802
Biomarker identification for statin sensitivity of cancer cell lines.Raghu, Vineet K; Beckwitt, Colin H; Warita, Katsuhiko; Wells, Alan; Benos, Panayiotis V; Oltvai, Zoltán NBiochemical and biophysical research communications.2018 01 01;29146185
Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells.Dioufa, Nikolina; Clark, Amanda M; Ma, Bo; Beckwitt, Colin H; Wells, AlanMolecular cancer.2017 Nov 14;29137633
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion.Nguyen, Eric H; Daly, William T; Le, Ngoc Nhi T; Farnoodian, Mitra; Belair, David G; Schwartz, Michael P; Lebakken, Connie S; Ananiev, Gene E; Saghiri, Mohammad Ali; Knudsen, Thomas B; Sheibani, Nader; Murphy, William LNature biomedical engineering.2017;29104816
The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the AdapGuetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William JSAGE open medicine.2017;29085638
Application of induced pluripotent stem cells to model smooth muscle cell function in vascular diseases.Ji, HaYeun; Kim, Hye Sung; Kim, Hae-Won; Leong, Kam WCurrent opinion in biomedical engineering.2017 Mar;29082353
Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology.Watson, David E; Hunziker, Rosemarie; Wikswo, John PExperimental biology and medicine (Maywood, N.J.).2017 Oct;29065799
Microphysiologic systems in female reproductive biology.Young, Alexandria N; Moyle-Heyrman, Georgette; Kim, J Julie; Burdette, Joanna EExperimental biology and medicine (Maywood, N.J.).2017 11;29065798
Self-contained, low-cost Body-on-a-Chip systems for drug development.Wang, Ying I; Oleaga, Carlota; Long, Christopher J; Esch, Mandy B; McAleer, Christopher W; Miller, Paula G; Hickman, James J; Shuler, Michael LExperimental biology and medicine (Maywood, N.J.).2017 11;29065797
Circadian hormone control in a human-on-a-chip: In vitro biology's ignored component?Cyr, Kevin J; Avaldi, Omero M; Wikswo, John PExperimental biology and medicine (Maywood, N.J.).2017 Nov;29065796
Concise Review: Current and Emerging Biomarkers of Nephrotoxicity.Weber, Elijah J; Himmelfarb, Jonathan; Kelly, Edward JCurrent opinion in toxicology.2017 Jun;29057384
MyD88-dependent inflammasome activation and autophagy inhibition contributes to Ehrlichia-induced liver injury and toxic shock.Kader, Muhamuda; Alaoui-El-Azher, Mounia; Vorhauer, Jennie; Kode, Bhushan B; Wells, Jakob Z; Stolz, Donna; Michalopoulos, George; Wells, Alan; Scott, Melanie; Ismail, NahedPLoS pathogens.2017 Oct;29049365
Biomechanical regulation of drug sensitivity in an engineered model of human tumor.Marturano-Kruik, A; Villasante, A; Yaeger, K; Ambati, S R; Chramiec, A; Raimondi, M T; Vunjak-Novakovic, GBiomaterials.2018 Jan;29040875
Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells.Lee, Jung Bok; Balikov, Daniel A; Yang, Jae Won; Kim, Ki Seok; Park, Hun Kuk; Kim, Jeong Koo; Kwon, Il Keun; Bellan, Leon M; Sung, Hak-JoonPolymers.2016 Jan;29034114
Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening.Lind, Johan U; Yadid, Moran; Perkins, Ian; O'Connor, Blakely B; Eweje, Feyisayo; Chantre, Christophe O; Hemphill, Matthew A; Yuan, Hongyan; Campbell, Patrick H; Vlassak, Joost J; Parker, Kevin KLab on a chip.2017 Oct 25;28976521
Cancer-associated fibroblasts support vascular growth through mechanical force.Sewell-Loftin, Mary Kathryn; Bayer, Samantha Van Hove; Crist, Elizabeth; Hughes, Taylor; Joison, Sofia M; Longmore, Gregory D; George, Steven CScientific reports.2017 Oct 03;28974764
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.Cruz, Nelly M; Song, Xuewen; Czerniecki, Stefan M; Gulieva, Ramila E; Churchill, Angela J; Kim, Yong Kyun; Winston, Kosuke; Tran, Linh M; Diaz, Marco A; Fu, Hongxia; Finn, Laura S; Pei, York; Himmelfarb, Jonathan; Freedman, Benjamin SNature materials.2017 Nov;28967916
In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4(+) T Lymphocytes.Matta, Poojitha; Sherrod, Stacy D; Marasco, Christina C; Moore, Daniel J; McLean, John A; Weitkamp, Joern-HendrikJournal of immunology (Baltimore, Md. : 1950).2017 Nov 01;28947540
RNA-Seq of Human Neural Progenitor Cells Exposed to Lead (Pb) Reveals Transcriptome Dynamics, Splicing Alterations and Disease Risk Associations.Jiang, Peng; Hou, Zhonggang; Bolin, Jennifer M; Thomson, James A; Stewart, RonToxicological sciences : an official journal of the Society of Toxicology.2017 Sep 01;28903495
Engineered Microvasculature in PDMS Networks Using Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.Sivarapatna, Amogh; Ghaedi, Mahboobe; Xiao, Yang; Han, Edward; Aryal, Binod; Zhou, Jing; Fernandez-Hernando, Carlos; Qyang, Yibing; Hirschi, Karen K; Niklason, Laura ECell transplantation.2017 08;28901188
A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells.Atchison, Leigh; Zhang, Haoyue; Cao, Kan; Truskey, George AScientific reports.2017 08 15;28811655
Tissue Engineering the Vascular Tree.Traore, Mahama A; George, Steven CTissue engineering. Part B, Reviews.2017 12;28799844
The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models.Gough, Albert; Vernetti, Lawrence; Bergenthal, Luke; Shun, Tong Ying; Taylor, D LansingApplied in vitro toxicology.2016 Jun 01;28781990
Microphysiological Systems to Assess Nonclinical Toxicity.Van Ness, Kirk P; Chang, Shih-Yu; Weber, Elijah J; Zumpano, Danielle; Eaton, David L; Kelly, Edward JCurrent protocols in toxicology.2017 Aug 04;28777442
3D Differentiation of LUHMES Cell Line to Study Recovery and Delayed Neurotoxic Effects.Harris, Georgina; Hogberg, Helena; Hartung, Thomas; Smirnova, LenaCurrent protocols in toxicology.2017 Aug 04;28777440
Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function.Alimperti, Stella; Mirabella, Teodelinda; Bajaj, Varnica; Polacheck, William; Pirone, Dana M; Duffield, Jeremy; Eyckmans, Jeroen; Assoian, Richard K; Chen, Christopher SProceedings of the National Academy of Sciences of the United States of America.2017 Aug 15;28765370
Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies.Tsamandouras, Nikolaos; Chen, Wen Li Kelly; Edington, Collin D; Stokes, Cynthia L; Griffith, Linda G; Cirit, MuratThe AAPS journal.2017 09;28752430
Detection of brain-directed autoantibodies in the serum of non-small cell lung cancer patients.Banjara, Manoj; Ghosh, Chaitali; Dadas, Aaron; Mazzone, Peter; Janigro, DamirPloS one.2017;28746384
Functional characterization of human pluripotent stem cell-derived arterial endothelial cells.Zhang, Jue; Chu, Li-Fang; Hou, Zhonggang; Schwartz, Michael P; Hacker, Timothy; Vickerman, Vernella; Swanson, Scott; Leng, Ning; Nguyen, Bao Kim; Elwell, Angela; Bolin, Jennifer; Brown, Matthew E; Stewart, Ron; Burlingham, William J; Murphy, William L; Thomson, James AProceedings of the National Academy of Sciences of the United States of America.2017 Jul 25;28696312
Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk.Chen, Wen L K; Edington, Collin; Suter, Emily; Yu, Jiajie; Velazquez, Jeremy J; Velazquez, Jason G; Shockley, Michael; Large, Emma M; Venkataramanan, Raman; Hughes, David J; Stokes, Cynthia L; Trumper, David L; Carrier, Rebecca L; Cirit, Murat; Griffith, Linda G; Lauffenburger, Douglas ABiotechnology and bioengineering.2017 Jul 01;28667746
* Extracellular Vesicles and Their Versatile Roles in Tissue Engineering.Jay, Steven M; Vunjak-Novakovic, GordanaTissue engineering. Part A.2017 Nov;28649910
3D Anastomosed Microvascular Network Model with Living Capillary Networks and Endothelial Cell-Lined Microfluidic Channels.Wang, Xiaolin; Phan, Duc T T; George, Steven C; Hughes, Christopher C W; Lee, Abraham PMethods in molecular biology (Clifton, N.J.).2017;28634954
Human iPS-derived endothelial cells for 3D microphysiological systems.Kurokawa, Yosuke K; Yin, Rose T; Shang, Michael R; Shirure, Venktesh S; Moya, Monica L; George, Steven CTissue engineering. Part C, Methods.2017 Jun 16;28622076
Low levels of physiological interstitial flow eliminate morphogen gradients and guide angiogenesis.Shirure, Venktesh S; Lezia, Andrew; Tao, Arnold; Alonzo, Luis F; George, Steven CAngiogenesis.2017 Jun 12;28608153
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques.Barry, Christopher; Schmitz, Matthew T; Propson, Nicholas E; Hou, Zhonggang; Zhang, Jue; Nguyen, Bao K; Bolin, Jennifer M; Jiang, Peng; McIntosh, Brian E; Probasco, Mitchell D; Swanson, Scott; Stewart, Ron; Thomson, James A; Schwartz, Michael P; Murphy, William LExperimental biology and medicine (Maywood, N.J.).2017 11;28599598
Next generation human skin constructs as advanced tools for drug development.Abaci, H E; Guo, Zongyou; Doucet, Yanne; Jacków, Joanna; Christiano, AngelaExperimental biology and medicine (Maywood, N.J.).2017 11;28592171
A Systematic Evaluation of Factors Affecting Extracellular Vesicle Uptake by Breast Cancer Cells.Stranford, Devin M; Hung, Michelle E; Gargus, Emma S; Shah, Ramille N; Leonard, Joshua NTissue engineering. Part A.2017 Jul 20;28586292
Gastrointestinal microphysiological systems.Blutt, Sarah E; Broughman, James R; Zou, Winnie; Zeng, Xi-Lei; Karandikar, Umesh C; In, Julie; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark; Estes, Mary KExperimental biology and medicine (Maywood, N.J.).2017 10;28534432
A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice.Laronda, Monica M; Rutz, Alexandra L; Xiao, Shuo; Whelan, Kelly A; Duncan, Francesca E; Roth, Eric W; Woodruff, Teresa K; Shah, Ramille NNature communications.2017 05 16;28509899
FGF-dependent metabolic control of vascular development.Yu, Pengchun; Wilhelm, Kerstin; Dubrac, Alexandre; Tung, Joe K; Alves, Tiago C; Fang, Jennifer S; Xie, Yi; Zhu, Jie; Chen, Zehua; De Smet, Frederik; Zhang, Jiasheng; Jin, Suk-Won; Sun, Lele; Sun, Hongye; Kibbey, Richard G; Hirschi, Karen K; Hay, Nissim; Carmeliet, Peter; Chittenden, Thomas W; Eichmann, Anne; Potente, Michael; Simons, MichaelNature.2017 05 11;28467822
Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.Soto-Gutierrez, Alejandro; Gough, Albert; Vernetti, Lawrence A; Taylor, D L; Monga, Satdarshan PExperimental biology and medicine (Maywood, N.J.).2017 10;28467181
JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement.Capulli, Andrew K; Emmert, Maximillian Y; Pasqualini, Francesco S; Kehl, Debora; Caliskan, Etem; Lind, Johan U; Sheehy, Sean P; Park, Sung Jin; Ahn, Seungkuk; Weber, Benedikt; Goss, Josue A; Hoerstrup, Simon P; Parker, Kevin KitBiomaterials.2017 Jul;28445803
A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms.Khazali, A S; Clark, A M; Wells, AStem cell reviews.2017 Apr 19;28425064
WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue.Loskill, Peter; Sezhian, Thiagarajan; Tharp, Kevin M; Lee-Montiel, Felipe T; Jeeawoody, Shaheen; Reese, Willie Mae; Zushin, Peter-James H; Stahl, Andreas; Healy, Kevin ELab on a chip.2017 May 02;28418430
Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.Lee-Montiel, Felipe T; George, Subin M; Gough, Albert H; Sharma, Anup D; Wu, Juanfang; DeBiasio, Richard; Vernetti, Lawrence A; Taylor, D LansingExperimental biology and medicine (Maywood, N.J.).2017 Oct;28409533
On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks.Valdez, Jorge; Cook, Christi D; Ahrens, Caroline Chopko; Wang, Alex J; Brown, Alexander; Kumar, Manu; Stockdale, Linda; Rothenberg, Daniel; Renggli, Kasper; Gordon, Elizabeth; Lauffenburger, Douglas; White, Forest; Griffith, LindaBiomaterials.2017 Jun;28371736
Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections.Zou, Winnie Y; Blutt, Sarah E; Crawford, Sue E; Ettayebi, Khalil; Zeng, Xi-Lei; Saxena, Kapil; Ramani, Sasirekha; Karandikar, Umesh C; Zachos, Nicholas C; Estes, Mary KMethods in molecular biology (Clifton, N.J.).2017 Mar 31;28361480
A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle.Xiao, Shuo; Coppeta, Jonathan R; Rogers, Hunter B; Isenberg, Brett C; Zhu, Jie; Olalekan, Susan A; McKinnon, Kelly E; Dokic, Danijela; Rashedi, Alexandra S; Haisenleder, Daniel J; Malpani, Saurabh S; Arnold-Murray, Chanel A; Chen, Kuanwei; Jiang, Mingyang; Bai, Lu; Nguyen, Catherine T; Zhang, Jiyang; Laronda, Monica M; Hope, Thomas J; Maniar, Kruti P; Pavone, Mary Ellen; Avram, Michael J; Sefton, Elizabeth C; Getsios, Spiro; Burdette, Joanna E; Kim, J Julie; Borenstein, Jeffrey T; Woodruff, Teresa KNature communications.2017 Mar 28;28350383
A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture.Zhang, Jue; Schwartz, Michael P; Hou, Zhonggang; Bai, Yongsheng; Ardalani, Hamisha; Swanson, Scott; Steill, John; Ruotti, Victor; Elwell, Angela; Nguyen, Bao Kim; Bolin, Jennifer; Stewart, Ron; Thomson, James A; Murphy, William LStem cell reports.2017 Apr 11;28343999
Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity.Davis, Brittany N J; Santoso, Jeffrey W; Walker, Michaela J; Cheng, Cindy S; Koves, Timothy R; Kraus, William E; Truskey, George ATissue engineering. Part C, Methods.2017 04;28338413
Doxorubicin Has Dose-Dependent Toxicity on Mouse Ovarian Follicle Development, Hormone Secretion, and Oocyte Maturation.Xiao, Shuo; Zhang, Jiyang; Liu, Mingjun; Iwahata, Hideyuki; Rogers, Hunter B; Woodruff, Teresa KToxicological sciences : an official journal of the Society of Toxicology.2017 06 01;28329872
Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture.Fontana, Gianluca; Gershlak, Joshua; Adamski, Michal; Lee, Jae-Sung; Matsumoto, Shion; Le, Hau D; Binder, Bernard; Wirth, John; Gaudette, Glenn; Murphy, William LAdvanced healthcare materials.2017 Apr;28319334
Multi-functional scaling methodology for translational pharmacokinetic and pharmacodynamic applications using integrated microphysiological systems (MPS).Maass, Christian; Stokes, Cynthia L; Griffith, Linda G; Cirit, MuratIntegrative biology : quantitative biosciences from nano to macro.2017 Apr 18;28267162
Laminar flow downregulates Notch activity to promote lymphatic sprouting.Choi, Dongwon; Park, Eunkyung; Jung, Eunson; Seong, Young Jin; Yoo, Jaehyuk; Lee, Esak; Hong, Mingu; Lee, Sunju; Ishida, Hiroaki; Burford, James; Peti-Peterdi, Janos; Adams, Ralf H; Srikanth, Sonal; Gwack, Yousang; Chen, Christopher S; Vogel, Hans J; Koh, Chester J; Wong, Alex K; Hong, Young-KwonThe Journal of clinical investigation.2017 Apr 03;28263185
Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease.Roach, Tracoyia; Alcendor, Donald JJournal of neuroinflammation.2017 Mar 03;28253931
Biologically Relevant Heterogeneity: Metrics and Practical Insights.Gough, Albert; Stern, Andrew M; Maier, John; Lezon, Timothy; Shun, Tong-Ying; Chennubhotla, Chakra; Schurdak, Mark E; Haney, Steven A; Taylor, D LansingSLAS discovery.2017 Mar;28231035
Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells.Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Najm, Imad M; Marchi, Nicola; Janigro, DamirEpilepsia.2017 Apr;28199000
Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface.Phan, Duc Tt; Bender, R Hugh F; Andrejecsk, Jillian W; Sobrino, Agua; Hachey, Stephanie J; George, Steven C; Hughes, Christopher CwExperimental biology and medicine (Maywood, N.J.).2017 11;28195514
The Contributions of Human Mini-Intestines to the Study of Intestinal Physiology and Pathophysiology.Yu, Huimin; Hasan, Nesrin M; In, Julie G; Estes, Mary K; Kovbasnjuk, Olga; Zachos, Nicholas C; Donowitz, MarkAnnual review of physiology.2017 Feb 10;28192061
The molecular basis of endothelial cell plasticity.Dejana, Elisabetta; Hirschi, Karen K; Simons, MichaelNature communications.2017 Feb 09;28181491
Species-specific developmental timing is maintained by pluripotent stem cells ex utero.Barry, Christopher; Schmitz, Matthew T; Jiang, Peng; Schwartz, Michael P; Duffin, Bret M; Swanson, Scott; Bacher, Rhonda; Bolin, Jennifer M; Elwell, Angela L; McIntosh, Brian E; Stewart, Ron; Thomson, James ADevelopmental biology.2017 Mar 15;28179190
Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.Vernetti, Lawrence; Gough, Albert; Baetz, Nicholas; Blutt, Sarah; Broughman, James R; Brown, Jacquelyn A; Foulke-Abel, Jennifer; Hasan, Nesrin; In, Julie; Kelly, Edward; Kovbasnjuk, Olga; Repper, Jonathan; Senutovitch, Nina; Stabb, Janet; Yeung, Catherine; Zachos, Nick C; Donowitz, Mark; Estes, Mary; Himmelfarb, Jonathan; Truskey, George; Wikswo, John P; Taylor, D LansingScientific reports.2017 Feb 08;28176881
A versatile platform for surface modification of microfluidic droplets.Li, Mingqiang; Jiang, Weiqian; Chen, Zaozao; Suryaprakash, Smruthi; Lv, Shixian; Tang, Zhaohui; Chen, Xuesi; Leong, Kam WLab on a chip.2017 Feb 14;28154857
A conceptual model for the development process of confirmatory adaptive clinical trials within an emergency research network.Mawocha, Samkeliso C; Fetters, Michael D; Legocki, Laurie J; Guetterman, Timothy C; Frederiksen, Shirley; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William JClinical trials (London, England).2017 Jun;28135827
Design considerations to minimize the impact of drug absorption in polymer-based organ-on-a-chip platforms.Shirure, V S; George, S CLab on a chip.2017 Feb 14;28102869
21st Century Cell Culture for 21st Century Toxicology.Pamies, David; Hartung, ThomasChemical research in toxicology.2017 01 17;28092941
A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.Phan, Duc T T; Wang, Xiaolin; Craver, Brianna M; Sobrino, Agua; Zhao, Da; Chen, Jerry C; Lee, Lilian Y N; George, Steven C; Lee, Abraham P; Hughes, Christopher C WLab on a chip.2017 01 31;28092382
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.Chang, Shih-Yu; Voellinger, Jenna L; Van Ness, Kirk P; Chapron, Brian; Shaffer, Rachel M; Neumann, Thomas; White, Collin C; Kavanagh, Terrance J; Kelly, Edward J; Eaton, David LToxicology in vitro : an international journal published in association with BIBRA.2017 Apr;28089783
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection.Saxena, Kapil; Simon, Lukas M; Zeng, Xi-Lei; Blutt, Sarah E; Crawford, Sue E; Sastri, Narayan P; Karandikar, Umesh C; Ajami, Nadim J; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, Mark; Conner, Margaret E; Shaw, Chad A; Estes, Mary KProceedings of the National Academy of Sciences of the United States of America.2017 Jan 24;28069942
Inhibition of ?v?5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.McCurley, Amy; Alimperti, Stella; Campos-Bilderback, Silvia B; Sandoval, Ruben M; Calvino, Jenna E; Reynolds, Taylor L; Quigley, Catherine; Mugford, Joshua W; Polacheck, William J; Gomez, Ivan G; Dovey, Jennifer; Marsh, Graham; Huang, Angela; Qian, Fang; Weinreb, Paul H; Dolinski, Brian M; Moore, Shaun; Duffield, Jeremy S; Chen, Christopher S; Molitoris, Bruce A; Violette, Shelia M; Crackower, Michael AJournal of the American Society of Nephrology : JASN.2017 Jun;28062569
Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.Pasqualini, Francesco S; Nesmith, Alexander P; Horton, Renita E; Sheehy, Sean P; Parker, Kevin KitBioMed research international.2016;28044126
Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.Hinson, J Travis; Chopra, Anant; Lowe, Andre; Sheng, Calvin C; Gupta, Rajat M; Kuppusamy, Rajarajan; O'Sullivan, John; Rowe, Glenn; Wakimoto, Hiroko; Gorham, Joshua; Zhang, Kehan; Musunuru, Kiran; Gerszten, Robert E; Wu, Sean M; Chen, Christopher S; Seidman, Jonathan G; Seidman, Christine ECell reports.2016 Dec 20;28009297
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit.Brown, Jacquelyn A; Codreanu, Simona G; Shi, Mingjian; Sherrod, Stacy D; Markov, Dmitry A; Neely, M Diana; Britt, Clayton M; Hoilett, Orlando S; Reiserer, Ronald S; Samson, Philip C; McCawley, Lisa J; Webb, Donna J; Bowman, Aaron B; McLean, John A; WikswoJournal of neuroinflammation.2016 Dec 12;27955696
Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease.Nakagawa, Naoki; Barron, Luke; Gomez, Ivan G; Johnson, Bryce G; Roach, Allie M; Kameoka, Sei; Jack, Richard M; Lupher Jr, Mark L; Gharib, Sina A; Duffield, Jeremy SJCI insight.2016 Dec 08;27942582
A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.Clark, A M; Wheeler, S E; Young, C L; Stockdale, L; Shepard Neiman, J; Zhao, W; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, ALab on a chip.2016 Dec 20;27910972
3D culture models of tissues under tension.Eyckmans, Jeroen; Chen, Christopher SJournal of cell science.2017 Jan 01;27909243
Improving the clinical management of traumatic brain injury through the pharmacokinetic modeling of peripheral blood biomarkers.Dadas, Aaron; Washington, Jolewis; Marchi, Nicola; Janigro, DamirFluids and barriers of the CNS.2016 Nov 30;27903281
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control.Coppeta, J R; Mescher, M J; Isenberg, B C; Spencer, A J; Kim, E S; Lever, A R; Mulhern, T J; Prantil-Baun, R; Comolli, J C; Borenstein, J TLab on a chip.;27901159
Good manufacturing practice requirements for the production of tissue vitrification and warming and recovery kits for clinical research.Laronda, Monica M; McKinnon, Kelly E; Ting, Alison Y; Le Fever, Ann V; Zelinski, Mary B; Woodruff, Teresa KJournal of assisted reproduction and genetics.;27900615
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity.Pamies, David; Barreras, Paula; Block, Katharina; Makri, Georgia; Kumar, Anupama; Wiersma, Daphne; Smirnova, Lenna; Zang, Ce; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Ming, Guo-Li; Berlinicke, Cindy J; Kyro, Kelly; Song, Hongjun; Pardo, Carlos A; Hartung, Thomas; Hogberg, Helena TALTEX.2017;27883356
Lipid profiling of polarized human monocyte-derived macrophages.Montenegro-Burke, J Rafael; Sutton, Jessica A; Rogers, Lisa M; Milne, Ginger L; McLean, John A; Aronoff, David MProstaglandins & other lipid mediators.2016 12;27871801
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for anti-secretory therapy of diarrheas caused by bacterial enterotoxins.Cil, Onur; Phuan, Puay-Wah; Gillespie, Anne Marie; Lee, Sujin; Tradtrantip, Lukmanee; Yin, Jianyi; Tse, Ming; Zachos, Nicholas C; Lin, Ruxian; Donowitz, Mark; Verkman, Alan SFASEB journal : official publication of the Federation of American Societies for Experimental Biology.2016 Nov 08;27871064
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.Workman, Michael J; Mahe, Maxime M; Trisno, Stephen; Poling, Holly M; Watson, Carey L; Sundaram, Nambirajan; Chang, Ching-Fang; Schiesser, Jacqueline; Aubert, Philippe; Stanley, Edouard G; Elefanty, Andrew G; Miyaoka, Yuichiro; Mandegar, Mohammad A; ConklNature medicine.2017 Jan;27869805
Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury.Leaf, Irina A; Nakagawa, Shunsaku; Johnson, Bryce G; Cha, Jin Joo; Mittelsteadt, Kristen; Guckian, Kevin M; Gomez, Ivan G; Altemeier, William A; Duffield, Jeremy SThe Journal of clinical investigation.2017 Jan 03;27869651
Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.Vernetti, Lawrence A; Vogt, Andreas; Gough, Albert; Taylor, D LansingClinics in liver disease.2017 02;27842772
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1? Production.Ceneri, Nicolle; Zhao, Lina; Young, Bryan D; Healy, Abigail; Coskun, Suleyman; Vasavada, Hema; Yarovinsky, Timur O; Ike, Kenneth; Pardi, Ruggero; Qin, Lingfen; Qin, Li; Tellides, George; Hirschi, Karen; Meadows, Judith; Soufer, Robert; Chun, Hyung J; SadeArteriosclerosis, thrombosis, and vascular biology.2017 Feb;27834690
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation.Cil, Onur; Phuan, Puay-Wah; Son, Jung-Ho; Zhu, Jie S; Ku, Colton K; Tabib, Niloufar Akhavan; Teuthorn, Andrew P; Ferrera, Loretta; Zachos, Nicholas C; Lin, Ruxian; Galietta, Luis J V; Donowitz, Mark; Kurth, Mark J; Verkman, Alan STranslational research : the journal of laboratory and clinical medicine.2017 Apr;27815136
A statistical approach for identifying differential distributions in single-cell RNA-seq experiments.Korthauer, Keegan D; Chu, Li-Fang; Newton, Michael A; Li, Yuan; Thomson, James; Stewart, Ron; Kendziorski, ChristinaGenome biology.2016 Oct 25;27782827
Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing.Lind, Johan U; Busbee, Travis A; Valentine, Alexander D; Pasqualini, Francesco S; Yuan, Hongyan; Yadid, Moran; Park, Sung-Jin; Kotikian, Arda; Nesmith, Alexander P; Campbell, Patrick H; Vlassak, Joost J; Lewis, Jennifer A; Parker, Kevin KNature materials.2016 Oct 24;27775708
Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System.Tsamandouras, N; Kostrzewski, T; Stokes, C L; Griffith, L G; Hughes, D J; Cirit, MThe Journal of pharmacology and experimental therapeutics.2017 Jan;27760784
Fringe instability in constrained soft elastic layers.Lin, Shaoting; Cohen, Tal; Zhang, Teng; Yuk, Hyunwoo; Abeyaratne, Rohan; Zhao, XuanheSoft matter.2016 Oct 12;27731462
Dynamic culture yields engineered myocardium with near-adult functional output.Jackman, Christopher P; Carlson, Aaron L; Bursac, NenadBiomaterials.2016 Dec;27723557
Organ Chips: Quality Assurance Systems in Regenerative Medicine.Pasqualini, Francesco S; Emmert, Maximillian Y; Parker, Kevin Kit; Hoerstrup, Simon PClinical pharmacology and therapeutics.2016 Oct 6;27709615
Tissue engineering of the heart: An evolving paradigm.Vunjak-Novakovic, GordanaThe Journal of thoracic and cardiovascular surgery.2017 03;27692954
Human mini-guts: new insights into intestinal physiology and host-pathogen interactions.In, Julie G; Foulke-Abel, Jennifer; Estes, Mary K; Zachos, Nicholas C; Kovbasnjuk, Olga; Donowitz, MarkNature reviews. Gastroenterology & hepatology.2016 Nov;27677718
Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors.Iannetti, Laura; D'Urso, Giovanna; Conoscenti, Gioacchino; Cutrì, Elena; Tuan, Rocky S; Raimondi, Manuela T; Gottardi, Riccardo; Zunino, PaoloPloS one.2016;27669413
S100B and S100B autoantibody as biomarkers for early detection of brain metastases in lung cancer.Choi, Humberto; Puvenna, Vikram; Brennan, Chanda; Mahmoud, Shamseldeen; Wang, Xiao-Feng; Phillips, Michael; Janigro, Damir; Mazzone, PeterTranslational lung cancer research.2016 Aug;27652205
High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro.Shan, Jing; Logan, David J; Root, David E; Carpenter, Anne E; Bhatia, Sangeeta NJournal of biomolecular screening.2016 Oct;27650791
Determination of ion mobility collision cross sections for unresolved isomeric mixtures using tandem mass spectrometry and chemometric deconvolution.Harper, Brett; Neumann, Elizabeth K; Stow, Sarah M; May, Jody C; McLean, John A; Solouki, TouradjAnalytica chimica acta.2016 Oct 05;27639144
Untargeted Metabolomics Strategies-Challenges and Emerging Directions.Schrimpe-Rutledge, Alexandra C; Codreanu, Simona G; Sherrod, Stacy D; McLean, John AJournal of the American Society for Mass Spectrometry.2016 Dec;27624161
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.Prasad, Bhagwat; Johnson, Katherine; Billington, Sarah; Lee, Caroline; Chung, Git W; Brown, Colin D A; Kelly, Edward J; Himmelfarb, Jonathan; Unadkat, Jashvant DDrug metabolism and disposition: the biological fate of chemicals.2016 Dec;27621205
Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.Long, Thomas J; Cosgrove, Patrick A; Dunn 2nd, Robert T; Stolz, Donna B; Hamadeh, Hisham; Afshari, Cynthia; McBride, Helen; Griffith, Linda GDrug metabolism and disposition: the biological fate of chemicals.2016 Dec;27621203
Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies.Hofer, Heidi R; Tuan, Rocky SStem cell research & therapy.2016 Sep 09;27612948
Biomimetic on-a-chip platforms for studying cancer metastasis.Lee, Esak; Song, H-H Greco; Chen, Christopher SCurrent opinion in chemical engineering.2016 Feb;27570735
Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface.Karthikeyan, Subbulakshmi; Lantvit, Daniel D; Chae, Dam Hee; Burdette, Joanna EOncotarget.2016 10 25;27563818
3D microtumors in vitro supported by perfused vascular networks.Sobrino, Agua; Phan, Duc T T; Datta, Rupsa; Wang, Xiaolin; Hachey, Stephanie J; Romero-López, Mónica; Gratton, Enrico; Lee, Abraham P; George, Steven C; Hughes, Christopher C WScientific reports.2016 Aug 23;27549930
Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle.Zhu, Jie; Xu, Yuanming; Rashedi, Alexandra S; Pavone, Mary Ellen; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna EMolecular human reproduction.2016 Nov;27542947
Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm.Chu, Li-Fang; Leng, Ning; Zhang, Jue; Hou, Zhonggang; Mamott, Daniel; Vereide, David T; Choi, Jeea; Kendziorski, Christina; Stewart, Ron; Thomson, James AGenome biology.2016 Aug 17;27534536
Development of a microphysiological model of human kidney proximal tubule function.Weber, Elijah J; Chapron, Alenka; Chapron, Brian D; Voellinger, Jenna L; Lidberg, Kevin A; Yeung, Catherine K; Wang, Zhican; Yamaura, Yoshiyuki; Hailey, Dale W; Neumann, Thomas; Shen, Danny D; Thummel, Kenneth E; Muczynski, Kimberly A; Himmelfarb, Jonathan; Kelly, Edward JKidney international.2016 Sep;27521113
Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips.Pensabene, Virginia; Costa, Lino; Terekhov, Alexander Y; Gnecco, Juan S; Wikswo, John P; Hofmeister, William HACS applied materials & interfaces.2016 Aug 31;27513606
Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures.Lizama-Manibusan, Britney N; Klein, Sharon; McKenzie, Jennifer R; Cliffel, David E; McLaughlin, BethAnnACS chemical neuroscience.2016 Sep 21;27504748
Liver Protects Metastatic Prostate Cancer From Induced Death by Activating E-cadherin Signaling.Ma, Bo; Wheeler, Sarah E; Clark, Amanda M; Whaley, Diana L; Yang, Min; Wells, AlanHepatology (Baltimore, Md.).2016 Aug 2;27482645
Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence.Nagao, Ryan J; Xu, Jin; Luo, Ping; Xue, Jun; Wang, Yi; Kotha, Surya; Zeng, Wen; Fu, Xiaoyun; Himmelfarb, Jonathan; Zheng, YingTissue engineering. Part A.2016 Aug 30;27481445
Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.Pattison, Amanda M; Blomain, Erik S; Merlino, Dante J; Wang, Fang; Crissey, Mary Ann S; Kraft, Crystal L; Rappaport, Jeff A; Snook, Adam E; Lynch, John P; Waldman, Scott AInfection and immunity.2016 Oct;27481254
Attitudes and opinions regarding confirmatory adaptive clinical trials: a mixed methods analysis from the Adaptive Designs Accelerating Promising Trials into Treatments (ADAPT-IT) project.Meurer, William J; Legocki, Laurie; Mawocha, Samkeliso; Frederiksen, Shirley M; Guetterman, Timothy C; Barsan, William; Lewis, Roger; Berry, Donald; Fetters, MichaelTrials.2016 Jul 29;27473126
Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells.Goligorsky, M S; Hirschi, KAdvances in pharmacology (San Diego, Calif.).2016;27451101
Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.Chang, Shih-Yu; Weber, Elijah J; Van Ness, Kirk P; Eaton, David L; Kelly, Edward JClinical pharmacology and therapeutics.2016 Jul 22;27448090
Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening.Wang, Ying I; Abaci, Hasan Erbil; Shuler, Michael LBiotechnology and bioengineering.2017 01;27399645
A recellularized human colon model identifies cancer driver genes.Chen, Huanhuan Joyce; Wei, Zhubo; Sun, Jian; Bhattacharya, Asmita; Savage, David J; Serda, Rita; Mackeyev, Yuri; Curley, Steven A; Bu, Pengcheng; Wang, Lihua; Chen, Shuibing; Cohen-Gould, Leona; Huang, Emina; Shen, Xiling; Lipkin, Steven M; Copeland, NealNature biotechnology.2016 Aug;27398792
Liver metastases: Microenvironments and ex-vivo models.Clark, Amanda M; Ma, Bo; Taylor, D Lansing; Griffith, Linda; Wells, AlanExperimental biology and medicine (Maywood, N.J.).2016 Sep;27390264
Phototactic guidance of a tissue-engineered soft-robotic ray.Park, Sung-Jin; Gazzola, Mattia; Park, Kyung Soo; Park, Shirley; Di Santo, Valentina; Blevins, Erin L; Lind, Johan U; Campbell, Patrick H; Dauth, Stephanie; Capulli, Andrew K; Pasqualini, Francesco S; Ahn, Seungkuk; Cho, Alexander; Yuan, Hongyan; Maoz, BeScience (New York, N.Y.).2016 Jul 8;27387948
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells.Yang, Min; Ma, Bo; Shao, Hanshuang; Clark, Amanda M; Wells, AlanBMC cancer.2016 Jul 07;27387344
Skin-inspired hydrogel-elastomer hybrids with robust interfaces and functional microstructures.Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Liu, Xinyue; Zhao, XuanheNature communications.2016 Jun 27;27345380
Isolation of Murine Embryonic Hemogenic Endothelial Cells.Fang, Jennifer S; Gritz, Emily C; Marcelo, Kathrina L; Hirschi, Karen KJournal of visualized experiments : JoVE.2016 06 17;27341393
Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells.Abaci, Hasan E; Guo, Zongyou; Coffman, Abigail; Gillette, Brian; Lee, Wen-Han; Sia, Samuel K; Christiano, Angela MAdvanced healthcare materials.2016 Jul;27333469
Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry.Hines, Kelly M; May, Jody C; McLean, John A; Xu, LibinAnalytical chemistry.2016 Jul 19;27321977
Pathophysiological implications of neurovascular P450 in brain disorders.Ghosh, Chaitali; Hossain, Mohammed; Solanki, Jesal; Dadas, Aaron; Marchi, Nicola; Janigro, DamirDrug discovery today.2016 Jun 14;27312874
Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge.May, Jody C; McLean, John AAnnual review of analytical chemistry (Palo Alto, Calif.).2016 Jun 12;27306312
Advancing cardiovascular tissue engineering.Truskey, George AF1000Research.2016;27303643
Engineering a perfusable 3D human liver platform from iPS cells.Schepers, Arnout; Li, Cheri; Chhabra, Arnav; Seney, Benjamin Tschudy; Bhatia, SangeetaLab on a chip.2016 Jul 5;27296616
Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC.Szymanska, Agnieszka F; Heylman, Christopher; Datta, Rupsa; Gratton, Enrico; Nenadic, ZoranComputers in biology and medicine.2016 Aug 1;27281718
Distilling complexity to advance cardiac tissue engineering.Ogle, Brenda M; Bursac, Nenad; Domian, Ibrahim; Huang, Ngan F; Menasché, Philippe; Murry, Charles E; Pruitt, Beth; Radisic, Milica; Wu, Joseph C; Wu, Sean M; Zhang, Jianyi; Zimmermann, Wolfram-Hubertus; Vunjak-Novakovic, GordanaScience translational medicine.2016 Jun 8;27280684
Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model.Villasante, Aranzazu; Marturano-Kruik, Alessandro; Ambati, Srikanth R; Liu, Zen; Godier-Furnemont, Amandine; Parsa, Hesam; Lee, Benjamin W; Moore, Malcolm A S; Vunjak-Novakovic, GordanaTheranostics.2016;27279906
Striated muscle function, regeneration, and repair.Shadrin, I Y; Khodabukus, A; Bursac, NCellular and molecular life sciences : CMLS.2016 Jun 6;27271751
A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation.McCarty, William J; Usta, O Berk; Yarmush, Martin LScientific reports.2016 May 31;27240736
Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes.Datta, Rupsa; Heylman, Christopher; George, Steven C; Gratton, EnricoBiomedical optics express.2016 May 1;27231614
Forces and mechanotransduction in 3D vascular biology.Kutys, Matthew L; Chen, Christopher SCurrent opinion in cell biology.2016 May 19;27209346
Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro.Capulli, Andrew K; MacQueen, Luke A; O'Connor, Blakely B; Dauth, Stephanie; Parker, Kevin KitCardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.2016 Jul-Aug;27174867
Modeling tumor microenvironments using custom-designed biomaterial scaffolds.Liu, Zen; Vunjak-Novakovic, GordanaCurrent opinion in chemical engineering.2016 Feb;27152253
Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response.Bale, Shyam Sundhar; Geerts, Sharon; Jindal, Rohit; Yarmush, Martin LScientific reports.2016 May 04;27142224
Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration.Jiang, Yangzi; Cai, Youzhi; Zhang, Wei; Yin, Zi; Hu, Changchang; Tong, Tong; Lu, Ping; Zhang, Shufang; Neculai, Dante; Tuan, Rocky S; Ouyang, Hong WeiStem cells translational medicine.2016 Jun;27130221
Bioengineered Models of Solid Human Tumors for Cancer Research.Marturano-Kruik, Alessandro; Villasante, Aranzazu; Vunjak-Novakovic, GordanaMethods in molecular biology (Clifton, N.J.).2016 Apr 27;27115504
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.Huebsch, Nathaniel; Loskill, Peter; Deveshwar, Nikhil; Spencer, C Ian; Judge, Luke M; Mandegar, Mohammad A; Fox, Cade B; Mohamed, Tamer M A; Ma, Zhen; Mathur, Anurag; Sheehan, Alice M; Truong, Annie; Saxton, Mike; Yoo, Jennie; Srivastava, Deepak; Desai, Tejal A; So, Po-Lin; Healy, Kevin E; Conklin, Bruce RScientific reports.2016;27095412
Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies?Chan, Hon Fai; Ma, Siying; Leong, Kam WRegenerative biomaterials.2016 Jun;27047674
Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions.Chan, Hon Fai; Zhang, Ying; Leong, Kam WSmall (Weinheim an der Bergstrasse, Germany).2016 May;27038291
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease.Gomez, Ivan G; Roach, Allie M; Nakagawa, Naoki; Amatucci, Aldo; Johnson, Bryce G; Dunn, Kadeshia; Kelly, Mark C; Karaca, Gamze; Zheng, Timothy S; Szak, Suzanne; Peppiatt-Wildman, Claire M; Burkly, Linda C; Duffield, Jeremy SJournal of the American Society of Nephrology : JASN.;27026366
A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.Stern, Andrew M; Schurdak, Mark E; Bahar, Ivet; Berg, Jeremy M; Taylor, D LansingJournal of biomolecular screening.2016 Jul;26962875
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels.Zanotelli, Matthew R; Ardalani, Hamisha; Zhang, Jue; Hou, Zhonggang; Nguyen, Eric H; Swanson, Scott; Nguyen, Bao Kim; Bolin, Jennifer; Elwell, Angela; Bischel, Lauren L; Xie, Angela W; Stewart, Ron; Beebe, David J; Thomson, James A; Schwartz, Michael P; Murphy, William LActa biomaterialia.2016 Apr 15;26945632
A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity.Bale, Shyam Sundhar; Sridharan, Gautham Vivek; Golberg, Inna; Prodanov, Ljupcho; McCarty, William J; Usta, Osman Berk; Jindal, Rohit; Yarmush, Martin LTechnology.2015 Dec;155-16226925437
Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues.Cheng, Cindy S; Ran, Lydia; Bursac, Nenad; Kraus, William E; Truskey, George ATissue engineering. Part A.2016 Apr;26891613
SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids.Tobita, Takamasa; Guzman-Lepe, Jorge; Takeishi, Kazuki; Nakao, Toshimasa; Wang, Yang; Meng, Fanying; Deng, Chu-Xia; Collin de l'Hortet, Alexandra; Soto-Gutierrez, AlejandroPloS one.2016;26890260
Human Vascular Microphysiological System for in vitro Drug Screening.Fernandez, C E; Yen, R W; Perez, S M; Bedell, H W; Povsic, T J; Reichert, W M; Truskey, G AScientific reports.2016;26888719
Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators.Moyle-Heyrman, Georgette; Schipma, Matthew J; Dean, Matthew; Davis, David A; Burdette, Joanna EJournal of ovarian research.2016 Feb 15;26879975
Transdifferentiation of human endothelial progenitors into smooth muscle cells.Ji, HaYeun; Atchison, Leigh; Chen, Zaozao; Chakraborty, Syandan; Jung, Youngmee; Truskey, George A; Christoforou, Nicolas; Leong, Kam WBiomaterials.2016 Apr;180-9426874281
Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue.Lee, Benjamin W; Liu, Bohao; Pluchinsky, Adam; Kim, Nathan; Eng, George; Vunjak-Novakovic, GordanaAdvanced healthcare materials.2016 Apr;26865105
Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy.Aratyn-Schaus, Yvonne; Pasqualini, Francesco S; Yuan, Hongyan; McCain, Megan L; Ye, George J C; Sheehy, Sean P; Campbell, Patrick H; Parker, Kevin KitThe Journal of cell biology.2016 Feb 15;26858266
Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids.In, Julie; Foulke-Abel, Jennifer; Zachos, Nicholas C; Hansen, Anne-Marie; Kaper, James B; Bernstein, Harris D; Halushka, Marc; Blutt, Sarah; Estes, Mary K; Donowitz, Mark; Kovbasnjuk, OlgaCellular and molecular gastroenterology and hepatology.2016 Jan 1;48-62.e326855967
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.Oleaga, Carlota; Bernabini, Catia; Smith, Alec S T; Srinivasan, Balaji; Jackson, Max; McLamb, William; Platt, Vivien; Bridges, Richard; Cai, Yunqing; Santhanam, Navaneetha; Berry, Bonnie; Najjar, Sarah; Akanda, Nesar; Guo, Xiufang; Martin, Candace; Ekman,Scientific reports.2016;26837601
Angiotensin II Induced Cardiac Dysfunction on a Chip.Horton, Renita E; Yadid, Moran; McCain, Megan L; Sheehy, Sean P; Pasqualini, Francesco S; Park, Sung-Jin; Cho, Alexander; Campbell, Patrick; Parker, Kevin KitPloS one.2016;26808388
High-density lipoprotein subclass measurements improve mortality risk prediction, discrimination and reclassification in a cardiac catheterization cohort.McGarrah, Robert W; Craig, Damian M; Haynes, Carol; Dowdy, Z Elaine; Shah, Svati H; Kraus, William EAtherosclerosis.2016 Mar;26803432
Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes.Eng, George; Lee, Benjamin W; Protas, Lev; Gagliardi, Mark; Brown, Kristy; Kass, Robert S; Keller, Gordon; Robinson, Richard B; Vunjak-Novakovic, GordanaNature communications.2016;26785135
OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data.Leng, Ning; Choi, Jeea; Chu, Li-Fang; Thomson, James A; Kendziorski, Christina; Stewart, RonBioinformatics (Oxford, England).2016 May 01;26743507
Tissue-Engineering for the Study of Cardiac Biomechanics.Ma, Stephen P; Vunjak-Novakovic, GordanaJournal of biomechanical engineering.2016 Feb;26720588
Tissue Engineering and Regenerative Medicine 2015: A Year in Review.Wobma, Holly; Vunjak-Novakovic, GordanaTissue engineering. Part B, Reviews.2016 Apr;26714410
Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.Yamaura, Yoshiyuki; Chapron, Brian D; Wang, Zhican; Himmelfarb, Jonathan; Thummel, Kenneth EDrug metabolism and disposition: the biological fate of chemicals.2016 Mar;26700954
Liver-Regenerative Transplantation: Regrow and Reset.Collin de l'Hortet, A; Takeishi, K; Guzman-Lepe, J; Handa, K; Matsubara, K; Fukumitsu, K; Dorko, K; Presnell, S C; Yagi, H; Soto-Gutierrez, AAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.2016 Jun;26699680
Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Heylman, Christopher; Datta, Rupsa; Sobrino, Agua; George, Steven; Gratton, EnricoPloS one.2015;26695765
Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification.Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Carpenter, Anne EMethods (San Diego, Calif.).2016 Mar 1;11-Jun26687239
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology.Foulke-Abel, Jennifer; In, Julie; Yin, Jianyi; Zachos, Nicholas C; Kovbasnjuk, Olga; Estes, Mary K; de Jonge, Hugo; Donowitz, MarkGastroenterology.2016 Mar;638-649.e826677983
Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology.Zachos, Nicholas C; Kovbasnjuk, Olga; Foulke-Abel, Jennifer; In, Julie; Blutt, Sarah E; de Jonge, Hugo R; Estes, Mary K; Donowitz, MarkThe Journal of biological chemistry.2016 Feb 19;26677228
A Novel Three-Dimensional Human Peritubular Microvascular System.Ligresti, Giovanni; Nagao, Ryan J; Xue, Jun; Choi, Yoon Jung; Xu, Jin; Ren, Shuyu; Aburatani, Takahide; Anderson, Susan K; MacDonald, James W; Bammler, Theo K; Schwartz, Stephen M; Muczynski, Kimberly A; Duffield, Jeremy S; Himmelfarb, Jonathan; Zheng, YiJournal of the American Society of Nephrology : JASN.2016 Aug;26657868
Fibrous scaffolds for building hearts and heart parts.Capulli, A K; MacQueen, L A; Sheehy, Sean P; Parker, K KAdvanced drug delivery reviews.2016 Jan 15;26656602
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis.Smirnova, L; Harris, G; Delp, J; Valadares, M; Pamies, D; Hogberg, H T; Waldmann, T; Leist, M; Hartung, TArchives of toxicology.2016 Nov;26647301
Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease.Bursac, Nenad; Juhas, Mark; Rando, Thomas AAnnual review of biomedical engineering.2015;26643021
Stretchable Hydrogel Electronics and Devices.Lin, Shaoting; Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Koo, Hyunwoo; Yu, Cunjiang; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Dec 7;26639322
Novel behavior of the chromatographic separation of linear and cyclic polymers.Montenegro-Burke, J Rafael; Bennett, Jackson M; McLean, John A; Hercules, David MAnalytical and bioanalytical chemistry.2016 Jan;677-8126637218
Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study.Guetterman, Timothy C; Fetters, Michael D; Legocki, Laurie J; Mawocha, Samkeliso; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William JClinical research and regulatory affairs.2015 Oct 2;121-13026622163
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.Wang, Xiaolin; Phan, Duc T T; Sobrino, Agua; George, Steven C; Hughes, Christopher C W; Lee, Abraham PLab on a chip.2016 Jan 21;26616908
Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model.Rivera-Burgos, Dinelia; Sarkar, Ujjal; Lever, Amanda R; Avram, Michael J; Coppeta, Jonathan R; Wishnok, John S; Borenstein, Jeffrey T; Tannenbaum, Steven RDrug metabolism and disposition: the biological fate of chemicals.2016 Feb;26586376
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1?/nerve growth factor signaling.Jiang, Yangzi; Hu, Changchang; Yu, Shuting; Yan, Junwei; Peng, Hsuan; Ouyang, Hong Wei; Tuan, Rocky SArthritis research & therapy.2015;32726577823
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; Shi, Mingjian; Britt, Clayton M; Hoilett, Orlando S; Yang, Qing; Brewer, Bryson M; Samson, Philip C; McCawley, Lisa J; May, James M; Webb, Donna J; Li, Deyu; BowBiomicrofluidics.2015 Sep;5412426576206
Is phosphorylated tau unique to chronic traumatic encephalopathy? Phosphorylated tau in epileptic brain and chronic traumatic encephalopathy.Puvenna, Vikram; Engeler, Madeline; Banjara, Manoj; Brennan, Chanda; Schreiber, Peter; Dadas, Aaron; Bahrami, Ashkon; Solanki, Jesal; Bandyopadhyay, Anasua; Morris, Jacqueline K; Bernick, Charles; Ghosh, Chaitali; Rapp, Edward; Bazarian, Jeffrey J; JanigrBrain research.2016 Jan 1;26556772
Tough bonding of hydrogels to diverse non-porous surfaces.Yuk, Hyunwoo; Zhang, Teng; Lin, Shaoting; Parada, German Alberto; Zhao, XuanheNature materials.2016 Feb;190-626552058
Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration.Yu, J; Cilfone, N A; Large, E M; Sarkar, U; Wishnok, J S; Tannenbaum, S R; Hughes, D J; Lauffenburger, D A; Griffith, L G; Stokes, C L; Cirit, MCPT: pharmacometrics & systems pharmacology.2015 Oct;26535159
Physiome-on-a-Chip: The Challenge of ''Scaling'' in Design, Operation, and Translation of Microphysiological Systems.Stokes, C L; Cirit, M; Lauffenburger, D ACPT: pharmacometrics & systems pharmacology.2015 Oct;26535154
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization.McCarty, William J; Prodanov, Ljupcho; Bale, Shyam Sundhar; Bhushan, Abhinav; Jindal, Rohit; Yarmush, Martin L; Usta, O BerkJournal of visualized experiments : JoVE.2015;26485274
Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status.Chun, Young Wook; Voyles, David E; Rath, Rutwik; Hofmeister, Lucas H; Boire, Timothy C; Wilcox, Henry; Lee, Jae Han; Bellan, Leon M; Hong, Charles C; Sung, Hak-JoonJournal of biomechanics.2015 Nov 5;26476764
Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells.Hofmeister, Lucas H; Costa, Lino; Balikov, Daniel A; Crowder, Spencer W; Terekhov, Alexander; Sung, Hak-Joon; Hofmeister, William HJournal of biological engineering.2015;26464581
Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia.Kong, Jianping; Sai, Hong; Crissey, Mary Ann S; Jhala, Nirag; Falk, Gary W; Ginsberg, Gregory G; Abrams, Julian A; Nakagawa, Hiroshi; Wang, Kenneth; Rustgi, Anil K; Wang, Timothy C; Lynch, John POncotarget.2015 Oct 20;32980-300526460825
Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels.Jung, Youngmee; Ji, HaYeun; Chen, Zaozao; Fai Chan, Hon; Atchison, Leigh; Klitzman, Bruce; Truskey, George; Leong, Kam WScientific reports.2015;1511626456074
Systems-Wide High-Dimensional Data Acquisition and Informatics Using Structural Mass Spectrometry Strategies.Sherrod, Stacy D; McLean, John AClinical chemistry.2016 Jan;26453699
RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis.Craciun, Florin L; Bijol, Vanesa; Ajay, Amrendra K; Rao, Poornima; Kumar, Ramya K; Hutchinson, John; Hofmann, Oliver; Joshi, Nikita; Luyendyk, James P; Kusebauch, Ulrike; Moss, Christopher L; Srivastava, Anand; Himmelfarb, Jonathan; Waikar, Sushrut S; Moritz, Robert L; Vaidya, Vishal SJournal of the American Society of Nephrology : JASN.2016 Jun;26449608
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology.Saxena, Kapil; Blutt, Sarah E; Ettayebi, Khalil; Zeng, Xi-Lei; Broughman, James R; Crawford, Sue E; Karandikar, Umesh C; Sastri, Narayan P; Conner, Margaret E; Opekun, Antone R; Graham, David Y; Qureshi, Waqar; Sherman, Vadim; Foulke-Abel, Jennifer; In, JJournal of virology.2015 Oct 07;26446608
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors.Thakore, Pratiksha I; Gersbach, Charles AMethods in molecular biology (Clifton, N.J.).2016;71-8826443215
The Development of TALE Nucleases for Biotechnology.Ousterout, David G; Gersbach, Charles AMethods in molecular biology (Clifton, N.J.).2016;27-4226443211
Enabling functional genomics with genome engineering.Hilton, Isaac B; Gersbach, Charles AGenome research.2015 Oct;1442-5526430154
In vitro cardiac tissue models: Current status and future prospects.Mathur, Anurag; Ma, Zhen; Loskill, Peter; Jeeawoody, Shaheen; Healy, Kevin EAdvanced drug delivery reviews.2016 Jan 15;203-1326428618
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin.Pellett, Sabine; Schwartz, Michael P; Tepp, William H; Josephson, Richard; Scherf, Jacob M; Pier, Christina L; Thomson, James A; Murphy, William L; Johnson, Eric AScientific reports.2015;1456626411797
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.Schwartz, Michael P; Hou, Zhonggang; Propson, Nicholas E; Zhang, Jue; Engstrom, Collin J; Santos Costa, Vitor; Jiang, Peng; Nguyen, Bao Kim; Bolin, Jennifer M; Daly, William; Wang, Yu; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James AProceedings of the National Academy of Sciences of the United States of America.2015 Oct 6;12516-2126392547
Hydrogel arrays formed via differential wettability patterning enable combinatorial screening of stem cell behavior.Le, Ngoc Nhi T; Zorn, Stefan; Schmitt, Samantha K; Gopalan, Padma; Murphy, William LActa biomaterialia.2016 Apr 1;26386315
Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.Kong, Jianping; Whelan, Kelly A; Laczkó, Dorottya; Dang, Brendan; Caro Monroig, Angeliz; Soroush, Ali; Falcone, John; Amaravadi, Ravi K; Rustgi, Anil K; Ginsberg, Gregory G; Falk, Gary W; Nakagawa, Hiroshi; Lynch, John PMolecular carcinogenesis.2015 Sep 16;26373456
Projection Stereolithographic Fabrication of Human Adipose Stem Cell-Incorporated Biodegradable Scaffolds for Cartilage Tissue Engineering.Sun, Aaron X; Lin, Hang; Beck, Angela M; Kilroy, Evan J; Tuan, Rocky SFrontiers in bioengineering and biotechnology.2015;26347860
In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells.Lee, Sue Hyun; Lee, Yunki; Chun, Young Wook; Crowder, Spencer W; Young, Pampee P; Park, Ki Dong; Sung, Hak-JoonAdvanced functional materials.2014 Nov 19;26327818
Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems.Berry, Bonnie J; Akanda, Nesar; Smith, Alec S T; Long, Christopher J; Schnepper, Mark T; Guo, Xiufang; Hickman, James JBiotechnology progress.2015 Nov-Dec;26317319
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.Hinson, John T; Chopra, Anant; Nafissi, Navid; Polacheck, William J; Benson, Craig C; Swist, Sandra; Gorham, Joshua; Yang, Luhan; Schafer, Sebastian; Sheng, Calvin C; Haghighi, Alireza; Homsy, Jason; Hubner, Norbert; Church, George; Cook, Stuart A; Linke,Science (New York, N.Y.).2015 Aug 28;26315439
The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury.Gomez, Ivan G; Duffield, Jeremy SKidney international supplements.2014 Nov;26312147
Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells.Gledhill, Karl; Guo, Zongyou; Umegaki-Arao, Noriko; Higgins, Claire A; Itoh, Munenari; Christiano, Angela MPloS one.2015;e013671326308443
Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments.Leng, Ning; Chu, Li-Fang; Barry, Chris; Li, Yuan; Choi, Jeea; Li, Xiaomao; Jiang, Peng; Stewart, Ron M; Thomson, James A; Kendziorski, ChristinaNature methods.2015 Oct;947-5026301841
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.Adler, Melanie; Ramm, Susanne; Hafner, Marc; Muhlich, Jeremy L; Gottwald, Esther Maria; Weber, Elijah; Jaklic, Alenka; Ajay, Amrendra Kumar; Svoboda, Daniel; Auerbach, Scott; Kelly, Edward J; Himmelfarb, Jonathan; Vaidya, Vishal SJournal of the American Society of Nephrology : JASN.2016 Apr;26260164
Use of ChemoFx® for Identification of Effective Treatments in Epithelial Ovarian Cancer.Richard, Scott; Wells, Alan; Connor, Joseph; Price, FredricPLoS currents.2015;26213638
Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip.Agarwal, Ashutosh; Farouz, Yohan; Nesmith, Alexander Peyton; Deravi, Leila F; McCain, Megan Laura; Parker, Kevin KitAdvanced functional materials.2013 Aug 12;3738-374626213529
Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening.Kurokawa, Yosuke K; George, Steven CAdvanced drug delivery reviews.2016 Jan 15;26212156
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes.Chun, Young Wook; Balikov, Daniel A; Feaster, Tromondae K; Williams, Charles H; Sheng, Calvin C; Lee, Jung-Bok; Boire, Timothy C; Neely, M Diana; Bellan, Leon M; Ess, Kevin C; Bowman, Aaron B; Sung, Hak-Joon; Hong, Charles CBiomaterials.2015 Oct;26204225
A human liver microphysiology platform for investigating physiology, drug safety, and disease models.Vernetti, Lawrence A; Senutovitch, Nina; Boltz, Robert; DeBiasio, Richard; Ying Shun, Tong; Gough, Albert; Taylor, D LansingExperimental biology and medicine (Maywood, N.J.).2016 Jan;101-1426202373
MALDI-TOF/TOF CID Study of Poly(1,4-dihydroxybenzene terephthalate) Fragmentation Reactions.Gies, Anthony P; Stow, Sarah M; McLean, John A; Hercules, David MPolymer.2015 May 1;26195848
Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer.May, Jody C; Dodds, James N; Kurulugama, Ruwan T; Stafford, George C; Fjeldsted, John C; McLean, John AThe Analyst.2015 Oct 21;26191544
Microfluidic device to control interstitial flow-mediated homotypic and heterotypic cellular communication.Alonzo, Luis F; Moya, Monica L; Shirure, Venktesh S; George, Steven CLab on a chip.2015 Sep 7;26190172
3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Jul 15;403426172844
Self-organizing human cardiac microchambers mediated by geometric confinement.Ma, Zhen; Wang, Jason; Loskill, Peter; Huebsch, Nathaniel; Koo, Sangmo; Svedlund, Felicia L; Marks, Natalie C; Hua, Ethan W; Grigoropoulos, Costas P; Conklin, Bruce R; Healy, Kevin ENature communications.2015;26172574
Endometriosis and ovarian cancer: links, risks, and challenges faced.Pavone, Mary Ellen; Lyttle, Brianna MInternational journal of women's health.2015;26170722
Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.Usta, O B; McCarty, W J; Bale, S; Hegde, M; Jindal, R; Bhushan, A; Golberg, I; Yarmush, M LTechnology.2015 Mar;26-Jan26167518
Long-term maintenance of a microfluidic 3D human liver sinusoid.Prodanov, Ljupcho; Jindal, Rohit; Bale, Shyam Sundhar; Hegde, Manjunath; McCarty, William J; Golberg, Inna; Bhushan, Abhinav; Yarmush, Martin L; Usta, Osman BerkBiotechnology and bioengineering.2016 Jan;241-626152452
Bioengineering methods for myocardial regeneration.Parsa, Hesam; Ronaldson, Kacey; Vunjak-Novakovic, GordanaAdvanced drug delivery reviews.2015 Jul 4;26150344
Biotunable acoustic node assembly of organoids.Chen, Pu; Güven, Sinan; Usta, Osman Berk; Yarmush, Martin L; Demirci, UtkanAdvanced healthcare materials.2015 Sep 16;26149464
Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs.Lee, Eugene K; Kurokawa, Yosuke K; Tu, Robin; George, Steven C; Khine, MichelleScientific reports.2015;26139150
Note: A single-chamber tool for plasma activation and surface functionalization in microfabrication.Bowman, Adam J; Scherrer, Joseph R; Reiserer, Ronald SThe Review of scientific instruments.2015 Jun;26133881
Development and validation of a microfluidic immunoassay capable of multiplexing parallel samples in microliter volumes.Ghodbane, Mehdi; Stucky, Elizabeth C; Maguire, Tim J; Schloss, Rene S; Shreiber, David I; Zahn, Jeffrey D; Yarmush, Martin LLab on a chip.2015 Aug 7;26130452
Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode.McKenzie, Jennifer R; Cognata, Andrew C; Davis, Anna N; Wikswo, John P; Cliffel, David EAnalytical chemistry.2015 Aug 4;7857-6426125545
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors.Bagley, Alexander F; Scherz-Shouval, Ruth; Galie, Peter A; Zhang, Angela Q; Wyckoff, Jeffrey; Whitesell, Luke; Chen, Christopher S; Lindquist, Susan; Bhatia, Sangeeta NCancer research.2015 Aug 15;3255-6726122846
Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation.Cambria, Elena; Renggli, Kasper; Ahrens, Caroline C; Cook, Christi D; Kroll, Carsten; Krueger, Andrew T; Imperiali, Barbara; Griffith, Linda GBiomacromolecules.2015 Aug 10;26098148
Blood-brain barrier, bulk flow, and interstitial clearance in epilepsy.Marchi, Nicola; Banjara, Manoj; Janigro, DamirJournal of neuroscience methods.2016 Feb 15;26093166
Comparative hazard analysis and toxicological modeling of diverse nanomaterials using the embryonic zebrafish (EZ) metric of toxicity.Harper, Bryan; Thomas, Dennis; Chikkagoudar, Satish; Baker, Nathan; Tang, Kaizhi; Heredia-Langner, Alejandro; Lins, Roberto; Harper, StaceyJournal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology.2015;26069453
''The state of the heart'': Recent advances in engineering human cardiac tissue from pluripotent stem cells.Sirabella, Dario; Cimetta, Elisa; Vunjak-Novakovic, GordanaExperimental biology and medicine (Maywood, N.J.).2015 Aug;26069271
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Jul 15;4035-4026033288
Tissue-engineered blood vessels as promising tools for testing drug toxicity.Truskey, George A; Fernandez, Cristina EExpert opinion on drug metabolism & toxicology.2015 Jul;1021-426028128
MicroRNA delivery for regenerative medicine.Peng, Bo; Chen, Yongming; Leong, Kam WAdvanced drug delivery reviews.2015 Jul 1;108-2226024978
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.Chen, Huanhuan Joyce; Sun, Jian; Huang, Zhiliang; Hou Jr, Harry; Arcilla, Myra; Rakhilin, Nikolai; Joe, Daniel J; Choi, Jiahn; Gadamsetty, Poornima; Milsom, Jeff; Nandakumar, Govind; Longman, Randy; Zhou, Xi Kathy; Edwards, Robert; Chen, Jonlin; Chen, KaiNature biotechnology.2015 Jun;656-6026006007
Fluorescence lifetime imaging of endogenous biomarker of oxidative stress.Datta, Rupsa; Alfonso-García, Alba; Cinco, Rachel; Gratton, EnricoScientific reports.2015;984825993434
Fluorescent protein biosensors applied to microphysiological systems.Senutovitch, Nina; Vernetti, Lawrence; Boltz, Robert; DeBiasio, Richard; Gough, Albert; Taylor, D LansingExperimental biology and medicine (Maywood, N.J.).2015 Jun;795-80825990438
A phenotypic in vitro model for the main determinants of human whole heart function.Stancescu, Maria; Molnar, Peter; McAleer, Christopher W; McLamb, William; Long, Christopher J; Oleaga, Carlota; Prot, Jean-Matthieu; Hickman, James JBiomaterials.2015 Aug;20-3025978005
Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies. 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers.Stow, Sarah M; Onifer, Tiffany M; Forsythe, Jay G; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David MAnalytical chemistry.2015 Jun 16;25971782
Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues.Feric, Nicole T; Radisic, MilicaAdvanced drug delivery reviews.2015 May 5;25956564
Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis.Legocki, Laurie J; Meurer, William J; Frederiksen, Shirley; Lewis, Roger J; Durkalski, Valerie L; Berry, Donald A; Barsan, William G; Fetters, Michael DBMC medical ethics.2015;2725933921
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor.Sarkar, Ujjal; Rivera-Burgos, Dinelia; Large, Emma M; Hughes, David J; Ravindra, Kodihalli C; Dyer, Rachel L; Ebrahimkhani, Mohammad R; Wishnok, John S; Griffith, Linda G; Tannenbaum, Steven RDrug metabolism and disposition: the biological fate of chemicals.2015 Jul;1091-925926431
Differential ?3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components.Merna, Nick; Fung, Kelsey M; Wang, Jean J; King, Cristi R; Hansen, Kirk C; Christman, Karen L; George, Steven CTissue engineering. Part A.2015 Aug;2195-20525926101
NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection.Juul, Sissel; Obliosca, Judy M; Liu, Cong; Liu, Yen-Liang; Chen, Yu-An; Imphean, Darren M; Knudsen, Birgitta R; Ho, Yi-Ping; Leong, Kam W; Yeh, Hsin-ChihNanoscale.2015 May 14;8332-725901841
The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study.Connor, Jason T; Broglio, Kristine R; Durkalski, Valerie; Meurer, William J; Johnston, Karen CTrials.2015;7225885963
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow.Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael LLab on a chip.2015 May 21;2269-7725857666
Culturing adult stem cells from mouse small intestinal crypts.Hamilton, Kathryn E; Crissey, Mary Ann S; Lynch, John P; Rustgi, Anil KCold Spring Harbor protocols.2015 Apr;354-825834260
A cost-effective RNA sequencing protocol for large-scale gene expression studies.Hou, Zhonggang; Jiang, Peng; Swanson, Scott A; Elwell, Angela L; Nguyen, Bao Kim S; Bolin, Jennifer M; Stewart, Ron; Thomson, James AScientific reports.2015;957025831155
Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI.Xu, Libin; Kliman, Michal; Forsythe, Jay G; Korade, Zeljka; Hmelo, Anthony B; Porter, Ned A; McLean, John AJournal of the American Society for Mass Spectrometry.2015 Jun;924-3325822928
Generating human intestinal tissues from pluripotent stem cells to study development and disease.Sinagoga, Katie L; Wells, James MThe EMBO journal.2015 May 5;1149-6325792515
Integration of drug, protein, and gene delivery systems with regenerative medicine.Lorden, Elizabeth R; Levinson, Howard M; Leong, Kam WDrug delivery and translational research.2015 Apr;168-8625787742
Engineering the ovarian cycle using in vitro follicle culture.Skory, Robin M; Xu, Yuanming; Shea, Lonnie D; Woodruff, Teresa KHuman reproduction (Oxford, England).2015 Jun;1386-9525784584
Engineering mesenchymal stem cells for regenerative medicine and drug delivery.Park, Ji Sun; Suryaprakash, Smruthi; Lao, Yeh-Hsing; Leong, Kam WMethods (San Diego, Calif.).2015 Aug;16-Mar25770356
Phage-display-guided nanocarrier targeting to atheroprone vasculature.Hofmeister, Lucas H; Lee, Sue Hyun; Norlander, Allison E; Montaniel, Kim Ramil C; Chen, Wei; Harrison, David G; Sung, Hak-JoonACS nano.2015;4435-4625768046
Human iPSC-based cardiac microphysiological system for drug screening applications.Mathur, Anurag; Loskill, Peter; Shao, Kaifeng; Huebsch, Nathaniel; Hong, SoonGweon; Marcus, Sivan G; Marks, Natalie; Mandegar, Mohammad; Conklin, Bruce R; Lee, Luke P; Healy, Kevin EScientific reports.2015;888325748532
Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models.Nakagawa, Hiroshi; Whelan, Kelly; Lynch, John PBest practice & research. Clinical gastroenterology.2015 Feb;16-Mar25743452
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling.Abaci, Hasan Erbil; Shuler, Michael LIntegrative biology : quantitative biosciences from nano to macro.2015 Apr;383-9125739725
Initiation of puberty in mice following decellularized ovary transplant.Laronda, Monica M; Jakus, Adam E; Whelan, Kelly A; Wertheim, Jason A; Shah, Ramille N; Woodruff, Teresa KBiomaterials.2015 May;20-925736492
Vessel network formation in response to intermittent hypoxia is frequency dependent.Ehsan, Seema M; George, Steven CJournal of bioscience and bioengineering.2015 Sep;347-5025735591
Structural phenotyping of stem cell-derived cardiomyocytes.Pasqualini, Francesco Silvio; Sheehy, Sean Paul; Agarwal, Ashutosh; Aratyn-Schaus, Yvonne; Parker, Kevin KitStem cell reports.2015 Mar 10;340-725733020
Real-time cellular exometabolome analysis with a microfluidic-mass spectrometry platform.Marasco, Christina C; Enders, Jeffrey R; Seale, Kevin T; McLean, John A; Wikswo, John PPloS one.2015;e011768525723555
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Majoros, William H; Reddy, Timothy E; Gersbach, Charles ANature communications.2015 Feb 18;624425692716
Development of a low-volume, highly sensitive microimmunoassay using computational fluid dynamics-driven multiobjective optimization.Ghodbane, Mehdi; Kulesa, Anthony; Yu, Henry H; Maguire, Tim J; Schloss, Rene R; Ramachandran, Rohit; Zahn, Jeffrey D; Yarmush, Martin LMicrofluidics and nanofluidics.2015 Feb;25691853
Use of an organotypic mammalian in vitro follicle growth assay to facilitate female reproductive toxicity screening.Xu, Yuanming; Duncan, Francesca E; Xu, Min; Woodruff, Teresa KReproduction, fertility, and development.2015 Feb 18;25689754
Charge Relaxation Dynamics of an Electrolytic Nanocapacitor.Thakore, Vaibhav; Hickman, James JThe journal of physical chemistry. C, Nanomaterials and interfaces.2015 Jan 29;25678941
S100B blood levels and childhood trauma in adolescent inpatients.Falcone, Tatiana; Janigro, Damir; Lovell, Rachel; Simon, Barry; Brown, Charles A; Herrera, Mariela; Myint, Aye Mu; Anand, AmitJournal of psychiatric research.2015 Mar;14-2225669696
CXCR3 in carcinoma progression.Ma, Bo; Khazali, Ahmad; Wells, AlanHistology and histopathology.2015 Jul;781-9225663474
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.Ng, Shengyong; Schwartz, Robert E; March, Sandra; Galstian, Ani; Gural, Nil; Shan, Jing; Prabhu, Mythili; Mota, Maria M; Bhatia, Sangeeta NStem cell reports.2015 Mar 10;348-5925660406
Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study.Ghosh, Chaitali; Hossain, Mohammad; Spriggs, Addison; Ghosh, Arnab; Grant, Gerald A; Marchi, Nicola; Perucca, Emilio; Janigro, DamirEpilepsia.2015 Mar;439-4925656284
Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers.Wang, Kezheng; Pan, Dipanjan; Schmieder, Anne H; Senpan, Angana; Hourcade, Dennis E; Pham, Christine T N; Mitchell, Lynne M; Caruthers, Shelton D; Cui, Grace; Wickline, Samuel A; Shen, Baozhong; Lanza, Gregory MNanomedicine : nanotechnology, biology, and medicine.2015 Apr;601-925652900
Developmental biology. Regional identity of gut stem cells--one gene to rule them all.Wells, James MNature reviews. Gastroenterology & hepatology.2015 Mar;125-625645971
Novel three dimensional human endocervix cultures respond to 28-day hormone treatment.Arslan, Sevim Yildiz; Yu, Yanni; Burdette, Joanne E; Pavone, Mary Ellen; Hope, Thomas J; Woodruff, Teresa K; Kim, J JulieEndocrinology.2015 Apr;1602-925635622
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.Furukawa, Masashi; Wheeler, Sarah; Clark, Amanda M; Wells, AlanPloS one.2015;e011806025635394
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.Bal-Price, Anna; Crofton, Kevin M; Leist, Marcel; Allen, Sandra; Arand, Michael; Buetler, Timo; Delrue, Nathalie; FitzGerald, Rex E; Hartung, Thomas; Heinonen, Tuula; Hogberg, Helena; Bennekou, Susanne Hougaard; Lichtensteiger, Walter; Oggier, Daniela; PaArchives of toxicology.2015 Feb;269-8725618548
Bioengineered tumors.Villasante, Aranzazu; Vunjak-Novakovic, GordanaBioengineered.2015;25616977
A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy.Pan, Dipanjan; Kim, Benjamin; Hu, Grace; Gupta, Deepti Sood; Senpan, Angana; Yang, Xiaoxia; Schmieder, Anne; Swain, Corban; Wickline, Samuel A; Tomasson, Michael H; Lanza, Gregory MNanomedicine (London, England).2015 Jan;241-5125600969
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status.Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschner, Michael; McLean, John A; Bowman, Aaron BMetallomics : integrated biometal science.2015 Feb;363-7025599126
Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.Jackman, Christopher P; Shadrin, Ilya Y; Carlson, Aaron L; Bursac, NenadCurrent opinion in chemical engineering.2015 Feb;57-6425599018
TEER measurement techniques for in vitro barrier model systems.Srinivasan, Balaji; Kolli, Aditya Reddy; Esch, Mandy Brigitte; Abaci, Hasan Erbil; Shuler, Michael L; Hickman, James JJournal of laboratory automation.2015 Apr;107-2625586998
Biology coming full circle: joining the whole and the parts.Wikswo, John P; Porter, Andrew PExperimental biology and medicine (Maywood, N.J.).2015 Jan;7-Mar25583953
Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs.Madden, Lauran; Juhas, Mark; Kraus, William E; Truskey, George A; Bursac, NenadeLife.2015;e0488525575180
Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease.Wilkerson, Irene; Laban, Joshua; Mitchell, Johnathan M; Sheibani, Nader; Alcendor, Donald JJournal of neuroinflammation.2015;225573478
Nanograting structure promotes lamellipodia-based cell collective migration and wound healing.Chen, Zaozao; Atchison, Leigh; Ji, HaYeun; Leong, Kam WConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.2014;2916-925570601
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.Vega, Maria E; Giroux, Véronique; Natsuizaka, Mitsuteru; Liu, Mingen; Klein-Szanto, Andres J; Stairs, Douglas B; Nakagawa, Hiroshi; Wang, Kenneth K; Wang, Timothy C; Lynch, John P; Rustgi, Anil KCell cycle (Georgetown, Tex.).2014;3857-6625558829
ýýýý*ýýý-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment.Zhang, Ruiying; Pan, Dipanjan; Cai, Xin; Yang, Xiaoxia; Senpan, Angana; Allen, John S; Lanza, Gregory M; Wang, Lihong VTheranostics.2015;124-3325553103
Origin and function of cartilage stem/progenitor cells in osteoarthritis.Jiang, Yangzi; Tuan, Rocky SNature reviews. Rheumatology.2015 Apr;206-1225536487
Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion.Warita, Katsuhiko; Warita, Tomoko; Beckwitt, Colin H; Schurdak, Mark E; Vazquez, Alexei; Wells, Alan; Oltvai, Zoltán NScientific reports.2014;759325534349
Three-dimensional modeling of the human fallopian tube fimbriae.Eddie, Sharon L; Quartuccio, Suzanne M; Zhu, Jie; Shepherd, Jessica A; Kothari, Rajul; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna EGynecologic oncology.2015 Feb;348-5425527363
Ion mobility-mass spectrometry: time-dispersive instrumentation.May, Jody C; McLean, John AAnalytical chemistry.2015 Feb 3;1422-3625526595
Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells.Kulangara, Karina; Yang, Jennifer; Chellappan, Malathi; Yang, Yong; Leong, Kam WPloS one.2014;e11469825521962
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain.Kabadi, Ami M; Thakore, Pratiksha I; Vockley, Christopher M; Ousterout, David G; Gibson, Tyler M; Guilak, Farshid; Reddy, Timothy E; Gersbach, Charles AACS synthetic biology.2015 Jun 19;689-9925494287
Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis.Chakraborty, Syandan; Ji, HaYeun; Chen, Jack; Gersbach, Charles A; Leong, Kam WScientific reports.2014;740325492703
Correction of dystrophin expression in cells from duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Perez-Pinera, Pablo; Brown, Matthew T; Majoros, William H; Reddy, Timothy E; Gersbach, Charles AMolecular therapy : the journal of the American Society of Gene Therapy.2015 Mar;523-3225492562
Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts.Xing, Qi; Vogt, Caleb; Leong, Kam W; Zhao, FengAdvanced functional materials.2014 May 28;3027-303525484849
Tenascin-C Signaling in melanoma.Shao, Hanshuang; Kirkwood, John M; Wells, AlanCell adhesion & migration.2015;125-3025482624
Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers.Wang, Hailong; Abhilash, A S; Chen, Christopher S; Wells, Rebecca G; Shenoy, Vivek BBiophysical journal.2014 Dec 2;2592-60325468338
Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology.May, Jody C; Goodwin, Cody R; McLean, John ACurrent opinion in biotechnology.2015 Feb;117-2125462629
A CRISPR/Cas9-based system for reprogramming cell lineage specification.Chakraborty, Syandan; Ji, HaYeun; Kabadi, Ami M; Gersbach, Charles A; Christoforou, Nicolas; Leong, Kam WStem cell reports.2014 Dec 9;940-725448066
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.Gomez, Ivan G; MacKenna, Deidre A; Johnson, Bryce G; Kaimal, Vivek; Roach, Allie M; Ren, Shuyu; Nakagawa, Naoki; Xin, Cuiyan; Newitt, Rick; Pandya, Shweta; Xia, Tai-He; Liu, Xueqing; Borza, Dorin-Bogdan; Grafals, Monica; Shankland, Stuart J; Himmelfarb, JThe Journal of clinical investigation.2015 Jan;141-5625415439
Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert.French, William R; Zimmerman, Lisa J; Schilling, Birgit; Gibson, Bradford W; Miller, Christine A; Townsend, R Reid; Sherrod, Stacy D; Goodwin, Cody R; McLean, John A; Tabb, David LJournal of proteome research.2015 Feb 6;1299-30725411686
Deficient Autophagy Results in Mitochondrial Dysfunction and FSGS.Kawakami, Takahisa; Gomez, Ivan G; Ren, Shuyu; Hudkins, Kelly; Roach, Allie; Alpers, Charles E; Shankland, Stuart J; D'Agati, Vivette D; Duffield, Jeremy SJournal of the American Society of Nephrology : JASN.2015 May;25406339
Patterning vascular networks in vivo for tissue engineering applications.Chaturvedi, Ritika R; Stevens, Kelly R; Solorzano, Ricardo D; Schwartz, Robert E; Eyckmans, Jeroen; Baranski, Jan D; Stapleton, Sarah Chase; Bhatia, Sangeeta N; Chen, Christopher STissue engineering. Part C, Methods.2015 May;509-1725390971
Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types.Hansen, Tyler D; Koepsel, Justin T; Le, Ngoc Nhi; Nguyen, Eric H; Zorn, Stefan; Parlato, Matthew; Loveland, Samuel G; Schwartz, Michael P; Murphy, William LBiomaterials science.2014 May;745-75625386339
Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes.Neiman, Jaclyn A Shepard; Raman, Ritu; Chan, Vincent; Rhoads, Mary G; Raredon, Micha Sam B; Velazquez, Jeremy J; Dyer, Rachel L; Bashir, Rashid; Hammond, Paula T; Griffith, Linda GBiotechnology and bioengineering.2015 Apr;777-8725384798
Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia.Brown, Jacquelyn A; Sherrod, Stacy D; Goodwin, Cody R; Brewer, Bryson; Yang, Lijie; Garbett, Krassimira A; Li, Deyu; McLean, John A; Wikswo, John P; Mirnics, KárolyJournal of neuroinflammation.2014;18325374324
ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response.Lee, Sue Hyun; Boire, Timothy C; Lee, Jung Bok; Gupta, Mukesh K; Zachman, Angela L; Rath, Rutwik; Sung, Hak-JoonJournal of materials chemistry. B, Materials for biology and medicine.2014 Nov 7;7109-711325343029
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.Huebsch, Nathaniel; Loskill, Peter; Mandegar, Mohammad A; Marks, Natalie C; Sheehan, Alice S; Ma, Zhen; Mathur, Anurag; Nguyen, Trieu N; Yoo, Jennie C; Judge, Luke M; Spencer, C Ian; Chukka, Anand C; Russell, Caitlin R; So, Po-Lin; Conklin, Bruce R; HealyTissue engineering. Part C, Methods.2015 May;467-7925333967
Macrophages modulate engineered human tissues for enhanced vascularization and healing.Spiller, Kara L; Freytes, Donald O; Vunjak-Novakovic, GordanaAnnals of biomedical engineering.2015 Mar;25331098
An in vivo model of human small intestine using pluripotent stem cells.Watson, Carey L; Mahe, Maxime M; Múnera, Jorge; Howell, Jonathan C; Sundaram, Nambirajan; Poling, Holly M; Schweitzer, Jamie I; Vallance, Jefferson E; Mayhew, Christopher N; Sun, Ying; Grabowski, Gregory; Finkbeiner, Stacy R; Spence, Jason R; Shroyer, NoaNature medicine.2014 Nov;25326803
On-demand hierarchical patterning with electric fields.Wang, Qiming; Robinson, Dominick; Zhao, XuanheApplied physics letters.2014 Jun 09;25316923
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system.Wheeler, S E; Clark, A M; Taylor, D P; Young, C L; Pillai, V C; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, ABritish journal of cancer.2014 Dec 9;2342-5025314052
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells.Coskun, Suleyman; Chao, Hsu; Vasavada, Hema; Heydari, Kartoosh; Gonzales, Naomi; Zhou, Xin; de Crombrugghe, Benoit; Hirschi, Karen KCell reports.2014 Oct 23;581-9025310984
A DNA-based molecular probe for optically reporting cellular traction forces.Blakely, Brandon L; Dumelin, Christoph E; Trappmann, Britta; McGregor, Lynn M; Choi, Colin K; Anthony, Peter C; Duesterberg, Van K; Baker, Brendon M; Block, Steven M; Liu, David R; Chen, Christopher SNature methods.2014 Dec;1229-3225306545
The magic touch: endothelial cells muscle-up adipose.Martin, Kathleen A; Hirschi, Karen KCirculation research.2014 Oct 10;752-425301822
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression.Boussadia, B; Ghosh, C; Plaud, C; Pascussi, J M; de Bock, F; Rousset, M C; Janigro, D; Marchi, NNeuroscience.2014 Oct 2;124-13425280786
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.Spencer, C Ian; Baba, Shiro; Nakamura, Kenta; Hua, Ethan A; Sears, Marie A F; Fu, Chi-cheng; Zhang, Jianhua; Balijepalli, Sadguna; Tomoda, Kiichiro; Hayashi, Yohei; Lizarraga, Paweena; Wojciak, Julianne; Scheinman, Melvin M; Aalto-Setälä, Katriina; MakielStem cell reports.2014 Aug 12;269-8125254341
Physicochemical signatures of nanoparticle-dependent complement activation.Thomas, Dennis G; Chikkagoudar, Satish; Heredia-Langer, Alejandro; Tardiff, Mark F; Xu, Zhixiang; Hourcade, Dennis E; Pham, Christine T N; Lanza, Gregory M; Weinberger, Kilian Q; Baker, Nathan AComputational science & discovery.2014 Mar 21;1500325254068
Long-term coculture strategies for primary hepatocytes and liver sinusoidal endothelial cells.Bale, Shyam Sundhar; Golberg, Inna; Jindal, Rohit; McCarty, William J; Luitje, Martha; Hegde, Manjunath; Bhushan, Abhinav; Usta, Osman Berk; Yarmush, Martin LTissue engineering. Part C, Methods.2015 Apr;25233394
Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases.Hines, Kelly M; Ballard, Billy R; Marshall, Dana R; McLean, John AMolecular bioSystems.2014 Nov;2827-3725212505
Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells.Belair, David G; Whisler, Jordan A; Valdez, Jorge; Velazquez, Jeremy; Molenda, James A; Vickerman, Vernella; Lewis, Rachel; Daigh, Christine; Hansen, Tyler D; Mann, David A; Thomson, James A; Griffith, Linda G; Kamm, Roger D; Schwartz, Michael P; Murphy, Stem cell reviews.2015 Jun;25190668
The relevance and potential roles of microphysiological systems in biology and medicine.Wikswo, John PExperimental biology and medicine (Maywood, N.J.).2014 Sep;25187571
Design of growth factor sequestering biomaterials.Belair, David G; Le, Ngoc Nhi; Murphy, William LChemical communications (Cambridge, England).2014 Dec 25;15651-6825182455
Bond-specific dissociation following excitation energy transfer for distance constraint determination in the gas phase.Hendricks, Nathan G; Lareau, Nichole M; Stow, Sarah M; McLean, John A; Julian, Ryan RJournal of the American Chemical Society.2014 Sep 24;25174489
Balanced UTE-SSFP for 19F MR imaging of complex spectra.Goette, Matthew J; Keupp, Jochen; Rahmer, Jürgen; Lanza, Gregory M; Wickline, Samuel A; Caruthers, Shelton DMagnetic resonance in medicine.2015 Aug;537-4325163853
Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels.Zachman, Angela L; Wang, Xintong; Tucker-Schwartz, Jason M; Fitzpatrick, Sean T; Lee, Sue H; Guelcher, Scott A; Skala, Melissa C; Sung, Hak-JoonBiomaterials.2014 Dec;25154665
Angiogenesis and airway reactivity in asthmatic Brown Norway rats.Wagner, Elizabeth M; Jenkins, John; Schmieder, Anne; Eldridge, Lindsey; Zhang, Qiong; Moldobaeva, Aigul; Zhang, Huiying; Allen, John S; Yang, Xiaoxia; Mitzner, Wayne; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory MAngiogenesis.2015 Jan;11-Jan25149641
Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications.Lee, Sue Hyun; Gupta, Mukesh K; Bang, Jae Beum; Bae, Hojae; Sung, Hak-JoonAdvanced healthcare materials.2013;908-1525136729
The role of mechanotransduction on vascular smooth muscle myocytes' [corrected] cytoskeleton and contractile function.Ye, George J C; Nesmith, Alexander P; Parker, Kevin KitAnatomical record (Hoboken, N.J. : 2007).2014 Sep;25125187
IL-1? associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.Wathen, Connor; Janigro, DamirEpilepsia.2014 Aug;25099305
Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation.Nesmith, Alexander Peyton; Agarwal, Ashutosh; McCain, Megan Laura; Parker, Kevin KitLab on a chip.2014 Oct 21;25093641
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.Shlomai, Amir; Schwartz, Robert E; Ramanan, Vyas; Bhatta, Ankit; de Jong, Ype P; Bhatia, Sangeeta N; Rice, Charles MProceedings of the National Academy of Sciences of the United States of America.2014 Aug 19;12193-825092305
Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes.Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi; Wrona, Emily A; Vunjak-Novakovic, GordanaMethods in molecular biology (Clifton, N.J.).2014;69-8125070328
Developing microphysiological systems for use as regulatory tools--challenges and opportunities.Andersen, Melvin E; Betts, Kellyn; Dragan, Yvonne; Fitzpatrick, Suzanne; Goodman, Jesse L; Hartung, Thomas; Himmelfarb, Jonathan; Ingber, Donald E; Jacobs, Abigail; Kavlock, Robert; Kolaja, Kyle; Stevens, James L; Tagle, Dan; Lansing Taylor, D; ThrockmortALTEX.2014;364-725061900
Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.Gough, Albert H; Chen, Ning; Shun, Tong Ying; Lezon, Timothy R; Boltz, Robert C; Reese, Celeste E; Wagner, Jacob; Vernetti, Lawrence A; Grandis, Jennifer R; Lee, Adrian V; Stern, Andrew M; Schurdak, Mark E; Taylor, D LansingPloS one.2014;25036749
Cell and tissue engineering for liver disease.Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S; Fox, Ira JScience translational medicine2014 Jul 16245sr225031271
Tissue-engineered microenvironment systems for modeling human vasculature.Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, ThomasExperimental biology and medicine (Maywood, N.J.).2014 Sep;1264-7125030480
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.Alépée, Natalie; Bahinski, Anthony; Daneshian, Mardas; De Wever, Bart; Fritsche, Ellen; Goldberg, Alan; Hansmann, Jan; Hartung, Thomas; Haycock, John; Hogberg, Helena; Hoelting, Lisa; Kelm, Jens M; Kadereit, Suzanne; McVey, Emily; Landsiedel, Robert; LeisALTEX.2014;441-7725027500
What non-neuronal mechanisms should be studied to understand epileptic seizures?Janigro, Damir; Walker, Matthew CAdvances in experimental medicine and biology.2014;25012382
Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases.Alexander, Peter G; Gottardi, Riccardo; Lin, Hang; Lozito, Thomas P; Tuan, Rocky SExperimental biology and medicine (Maywood, N.J.).2014 Sep;1080-9524994814
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury.Esch, Mandy B; Mahler, Gretchen J; Stokol, Tracy; Shuler, Michael LLab on a chip.2014 Aug 21;3081-9224970651
Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use.Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Eastaway, Adriene; Cortiella, JoaquinExperimental biology and medicine (Maywood, N.J.).2014 Sep;1135-6924962174
Using physiologically-based pharmacokinetic-guided ''body-on-a-chip'' systems to predict mammalian response to drug and chemical exposure.Sung, Jong Hwan; Srinivasan, Balaji; Esch, Mandy Brigitte; McLamb, William T; Bernabini, Catia; Shuler, Michael L; Hickman, James JExperimental biology and medicine (Maywood, N.J.).2014 Sep;1225-3924951471
Challenges and promises in modeling dermatologic disorders with bioengineered skin.Eungdamrong, Narat J; Higgins, Claire; Guo, Zongyou; Lee, Wen-Han; Gillette, Brian; Sia, Samuel; Christiano, Angela MExperimental biology and medicine (Maywood, N.J.).2014 Sep;1215-2424951469
Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide.Zhou, Hui-fang; Yan, Huimin; Hu, Ying; Springer, Luke E; Yang, Xiaoxia; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T NACS nano2014 Jul 227305-1724941020
A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture.McCarty, William J; Usta, O Berk; Luitje, Martha; Bale, Shyam Sundhar; Bhushan, Abhinav; Hegde, Manjunath; Golberg, Inna; Jindal, Rohit; Yarmush, Martin LTechnology.2014 Mar;67-7424932459
Physiology and metabolism of tissue-engineered skeletal muscle.Cheng, Cindy S; Davis, Brittany N J; Madden, Lauran; Bursac, Nenad; Truskey, George AExperimental biology and medicine (Maywood, N.J.).2014 Sep;1203-1424912506
Biological and medical applications of a brain-on-a-chip.Pamies, David; Hartung, Thomas; Hogberg, Helena TExperimental biology and medicine (Maywood, N.J.).2014 Sep;1096-10724912505
Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers.Daily, Michael D; Olsen, Brett N; Schlesinger, Paul H; Ory, Daniel S; Baker, Nathan AJournal of chemical theory and computation.2014 May 13;24910542
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro.Smith, A S T; Long, C J; Pirozzi, K; Najjar, S; McAleer, C; Vandenburgh, H H; Hickman, J JJournal of biotechnology.2014 Sep 20;15-824909944
Induced pluripotent stem cells for regenerative medicine.Hirschi, Karen K; Li, Song; Roy, KrishnenduAnnual review of biomedical engineering.2014 Jul 11;277-9424905879
Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems.Marasco, Christina C; Goodwin, Cody R; Winder, Danny G; Schramm-Sapyta, Nicole L; McLean, John A; Wikswo, John PExperimental biology and medicine (Maywood, N.J.).2014 Nov;1433-4224903164
Cellular and molecular mechanisms in kidney fibrosis.Duffield, Jeremy SThe Journal of clinical investigation.2014 Jun;24892703
Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover.Evans, J Corey; Hines, Kelly M; Forsythe, Jay G; Erdogan, Begum; Shi, Mingjian; Hill, Salisha; Rose, Kristie L; McLean, John A; Webb, Donna JJournal of proteome research.2014 Jul 3;3303-1324874604
Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury.Chen, Yi-Ting; Chang, Yu-Ting; Pan, Szu-Yu; Chou, Yu-Hsiang; Chang, Fan-Chi; Yeh, Pei-Ying; Liu, Yuan-Hung; Chiang, Wen-Chih; Chen, Yung-Ming; Wu, Kwan-Dun; Tsai, Tun-Jun; Duffield, Jeremy S; Lin, Shuei-LiongJournal of the American Society of Nephrology : JASN.2014 Dec;24854266
Ovarian cancer in endometriosis: clinical and molecular aspects.Lyttle, B; Bernardi, L; Pavone, M EMinerva ginecologica2014 Apr155-6424848074
Fluid shear stress threshold regulates angiogenic sprouting.Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K; Cohen, Daniel M; Janmey, Paul A; Chen, Christopher SProceedings of the National Academy of Sciences of the United States of America2014 Jun 37968-7324843171
Intracerebral hemorrhage mortality is not changing despite declining incidence.Zahuranec, Darin B; Lisabeth, Lynda D; Sanchez, Brisa N; Smith, Melinda A; Brown, Devin L; Garcia, Nelda M; Skolarus, Lesli E; Meurer, William J; Burke, James F; Adelman, Eric E; Morgenstern, Lewis BNeurology2014 Jun 172180-624838789
Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks.Zhao, XuanheSoft matter.2014 Feb 7;672-8724834901
MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation.Bulte, Jeff W M; Schmieder, Anne H; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory MNanomedicine : nanotechnology, biology, and medicine.2014 Oct;1385-824832959
Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1?.Lin, Hang; Lozito, Thomas P; Alexander, Peter G; Gottardi, Riccardo; Tuan, Rocky SMolecular pharmaceutics.2014 Jul 7;2203-1224830762
Approaching the in vitro clinical trial: engineering organs on chips.Capulli, A K; Tian, K; Mehandru, N; Bukhta, A; Choudhury, S F; Suchyta, M; Parker, K KLab on a chip.2014 Sep 7;3181-624828385
A microphysiological system model of therapy for liver micrometastases.Clark, Amanda M; Wheeler, Sarah E; Taylor, Donald P; Pillai, Venkateswaran C; Young, Carissa L; Prantil-Baun, Rachelle; Nguyen, Transon; Stolz, Donna B; Borenstein, Jeffrey T; Lauffenburger, Douglas A; Venkataramanan, Raman; Griffith, Linda G; Wells, AlanExperimental biology and medicine (Maywood, N.J.).2014 Sep;1170-924821820
Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent.Wang, Xintong; Zachman, Angela L; Chun, Young Wook; Shen, Fang-Wen; Hwang, Yu-Shik; Sung, Hak-JoonInternational journal of cardiology.2014 Jul 1;688-9524820736
Materials innovation for co-delivery of diverse therapeutic cargos.Godsey, Megan E; Suryaprakash, Smruthi; Leong, Kam WRSC advances.2013 Dec 21;24794-2481124818000
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.Wang, Gang; McCain, Megan L; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-Zhi; Li, Kai; Wang,Nature medicine.2014 Jun;616-2324813252
Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits.Puvenna, Vikram; Brennan, Chanda; Shaw, Gerald; Yang, Cui; Marchi, Nicola; Bazarian, Jeffrey J; Merchant-Borna, Kian; Janigro, DamirPloS one.2014;e9629624806476
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.Ebrahimkhani, Mohammad R; Young, Carissa L; Lauffenburger, Douglas A; Griffith, Linda G; Borenstein, Jeffrey TDrug discovery today2014 Jun754-6224793141
Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems.Hartman, Kira G; Bortner Jr, James D; Falk, Gary W; Ginsberg, Gregory G; Jhala, Nirag; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John PExperimental biology and medicine (Maywood, N.J.).2014 Sep;1108-2324781339
Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform.Hegde, Manjunath; Jindal, Rohit; Bhushan, Abhinav; Bale, Shyam Sundhar; McCarty, William J; Golberg, Inna; Usta, O Berk; Yarmush, Martin LLab on a chip.2014 Jun 21;2033-924770663
Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research.Abrams, Julian A; Appelman, Henry D; Beer, David G; Berry, Lynne D; Chak, Amitabh; Falk, Gary W; Fitzgerald, Rebecca C; Ginsberg, Gregory G; Grady, William M; Joshi, Bishnu P; Lynch, John P; Markowitz, Sanford; Richmond, Ellen S; Rustgi, Anil K; Seibel, EGastroenterology.2014 Jun;1586-9024768332
In vitro platforms for evaluating liver toxicity.Bale, Shyam Sundhar; Vernetti, Lawrence; Senutovitch, Nina; Jindal, Rohit; Hegde, Manjunath; Gough, Albert; McCarty, William J; Bakan, Ahmet; Bhushan, Abhinav; Shun, Tong Y; Golberg, Inna; DeBiasio, Richard; Usta, O Berk; Taylor, D Lansing; Yarmush, MartiExperimental biology and medicine (Maywood, N.J.).2014 Sep;1180-9124764241
A three-dimensional in vitro model of tumor cell intravasation.Ehsan, Seema M; Welch-Reardon, Katrina M; Waterman, Marian L; Hughes, Christopher C W; George, Steven CIntegrative biology : quantitative biosciences from nano to macro.2014 Jun;603-1024763498
Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC? signaling.Cha, Boyoung; Chen, Tiane; Sarker, Rafiquel; Yang, Jianbo; Raben, Daniel; Tse, C Ming; Kovbasnjuk, Olga; Donowitz, MarkAmerican journal of physiology. Cell physiology.2014 Jul 1;C55-6524760985
A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.Heylman, Christopher; Sobrino, Agua; Shirure, Venktesh S; Hughes, Christopher Cw; George, Steven CExperimental biology and medicine (Maywood, N.J.).2014 Sep;1240-5424740872
Microphysiological modeling of the reproductive tract: A fertile endeavor.Eddie, Sharon L; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna EExperimental biology and medicine (Maywood, N.J.)2014 Apr 15NULL24737736
Microscale technologies for regulating human stem cell differentiation.Cimetta, Elisa; Vunjak-Novakovic, GordanaExperimental biology and medicine (Maywood, N.J.).2014 Sep;1255-6324737735
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues.McCain, Megan L; Agarwal, Ashutosh; Nesmith, Haley W; Nesmith, Alexander P; Parker, Kevin KitBiomaterials.2014 Jul;5462-7124731714
Integrating in vitro organ-specific function with the microcirculation.Moya, Monica L; George, Steven CCurrent opinion in chemical engineering.2014 Feb 1;103-11124729953
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using *(v)*ýýý-targeted theranostic nanoparticles.Pan, Dipanjan; Schmieder, Anne H; Wang, Kezheng; Yang, Xiaoxia; Senpan, Angana; Cui, Grace; Killgore, Kendall; Kim, Benjamin; Allen, John S; Zhang, Huiying; Caruthers, Shelton D; Shen, Baozhong; Wickline, Samuel A; Lanza, Gregory MTheranostics2014565-7824723979
3D - a new dimension of in vitro research.Hartung, ThomasAdvanced drug delivery reviews.2014 Apr;vi24721291
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract.Foulke-Abel, Jennifer; In, Julie; Kovbasnjuk, Olga; Zachos, Nicholas C; Ettayebi, Khalil; Blutt, Sarah E; Hyser, Joseph M; Zeng, Xi-Lei; Crawford, Sue E; Broughman, James R; Estes, Mary K; Donowitz, MarkExperimental biology and medicine (Maywood, N.J.).2014 Sep;1124-3424719375
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons.Kulangara, Karina; Adler, Andrew F; Wang, Hong; Chellappan, Malathi; Hammett, Ellen; Yasuda, Ryohei; Leong, Kam WBiomaterials.2014 Jul;5327-3624709523
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.Smirnova, Lena; Hogberg, Helena T; Leist, Marcel; Hartung, ThomasALTEX2014129-5624687333
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.McCain, Megan L; Yuan, Hongyan; Pasqualini, Francesco S; Campbell, Patrick H; Parker, Kevin KitAmerican journal of physiology. Heart and circulatory physiology.2014 Jun 1;H1525-3924682394
Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers.Forsythe, Jay G; Stow, Sarah M; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David MAnalytical chemistry.2014 May 6;4362-7024678803
Quality metrics for stem cell-derived cardiac myocytes.Sheehy, Sean P; Pasqualini, Francesco; Grosberg, Anna; Park, Sung Jin; Aratyn-Schaus, Yvonne; Parker, Kevin KitStem cell reports.2014 Mar 11;282-9424672752
Engineering Liver.Griffith, Linda G; Wells, Alan; Stolz, Donna BeerHepatology (Baltimore, Md.)2014 Mar 26NULL24668880
Antagonizing the *v *3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading.Tomlinson, Ryan E; Schmieder, Anne H; Quirk, James D; Lanza, Gregory M; Silva, Matthew JJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.2014 Sep;1970-8024644077
Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening.Zhao, Ruogang; Chen, Christopher S; Reich, Daniel HBiomaterials.2014 Jun;5056-6424630092
Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor.Diederichs, Solvig; Tuan, Rocky SStem cells and development.2014 Jul 15;1594-61024625206
The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells.Ma, Bo; Wells, AlanThe Journal of biological chemistry.2014 Apr 18;11153-6124619413
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition.Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, AlanBreast cancer research and treatment2014 Apr551-6024610032
Bioreactor technologies to support liver function in vitro.Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B; Hughes, David J; Griffith, Linda GAdvanced drug delivery reviews2014 Apr132-5724607703
Myocardial tissue engineering: in vitro models.Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, ChristineCold Spring Harbor perspectives in medicine.2014 Mar;24591534
Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain.Crowder, Spencer W; Balikov, Daniel A; Hwang, Yu-Shik; Sung, Hak-JoonCurrent pathobiology reports.2014 Mar;33-4024587979
Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution.Lin, Hang; Cheng, Anthony Wai-Ming; Alexander, Peter G; Beck, Angela M; Tuan, Rocky STissue engineering. Part A.2014 Sep;2402-1124575844
Three-dimensional paper-based model for cardiac ischemia.Mosadegh, Bobak; Dabiri, Borna E; Lockett, Matthew R; Derda, Ratmir; Campbell, Patrick; Parker, Kevin Kit; Whitesides, George MAdvanced healthcare materials.2014 Jul;1036-4324574054
Mouse liver repopulation with hepatocytes generated from human fibroblasts.Zhu, Saiyong; Rezvani, Milad; Harbell, Jack; Mattis, Aras N; Wolfe, Alan R; Benet, Leslie Z; Willenbring, Holger; Ding, ShengNature.2014 Apr 3;93-724572354
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans.Bhushan, Abhinav; Senutovitch, Nina; Bale, Shyam S; McCarty, William J; Hegde, Manjunath; Jindal, Rohit; Golberg, Inna; Berk Usta, O; Yarmush, Martin L; Vernetti, Lawrence; Gough, Albert; Bakan, Ahmet; Shun, Tong Ying; DeBiasio, Richard; Lansing Taylor, DStem cell research & therapy.2013;S1624565476
An integrated in vitro model of perfused tumor and cardiac tissue.Moya, Monica; Tran, David; George, Steven CStem cell research & therapy.2013;S1524565445
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.Mathur, Anurag; Loskill, Peter; Hong, Soongweon; Lee, Jae; Marcus, Sivan G; Dumont, Laure; Conklin, Bruce R; Willenbring, Holger; Lee, Luke P; Healy, Kevin EStem cell research & therapy.2013;S1424565415
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment.Laronda, Monica M; Burdette, Joanna E; Kim, J; Woodruff, Teresa KStem cell research & therapy2013S1324565375
A human pluripotent stem cell platform for assessing developmental neural toxicity screening.Hou, Zhonggang; Zhang, Jue; Schwartz, Michael P; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James AStem cell research & therapy.2013;S1224565336
All-human microphysical model of metastasis therapy.Wheeler, Sarah E; Borenstein, Jeffrey T; Clark, Amanda M; Ebrahimkhani, Mohammad R; Fox, Ira J; Griffith, Linda; Inman, Walker; Lauffenburger, Douglas; Nguyen, Transon; Pillai, Venkateswaran C; Prantil-Baun, Rachelle; Stolz, Donna B; Taylor, Donald; UlricStem cell research & therapy.2013;S1124565274
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing.Truskey, George A; Achneck, Hardean E; Bursac, Nenad; Chan, Hon; Cheng, Cindy S; Fernandez, Cristina; Hong, Sungmin; Jung, Youngmee; Koves, Tim; Kraus, William E; Leong, Kam; Madden, Lauran; Reichert, William M; Zhao, XuanheStem cell research & therapy.2013;S1024565225
Building additional complexity to in vitro-derived intestinal tissues.Brugmann, Samantha A; Wells, James MStem cell research & therapy.2013;S124565179
Microphysiological systems and low-cost microfluidic platform with analytics.Smith, Alec S T; Long, Christopher J; Berry, Bonnie J; McAleer, Christopher; Stancescu, Maria; Molnar, Peter; Miller, Paula G; Esch, Mandy B; Prot, Jean-Matthieu; Hickman, James J; Shuler, Michael LStem cell research & therapy.2013;S924565109
HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease.Vunjak-Novakovic, Gordana; Bhatia, Sangeeta; Chen, Christopher; Hirschi, KarenStem cell research & therapy2013S824565063
Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology.Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Cortiella, JoaquinStem cell research & therapy.2013;S724565038
Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis.Lozito, Thomas P; Alexander, Peter G; Lin, Hang; Gottardi, Riccardo; Cheng, Anthony Wai-Ming; Tuan, Rocky SStem cell research & therapy.2013;S624564995
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems.Hartman, Kira G; Bortner, James D; Falk, Gary W; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John PStem cell research & therapy.2013;S524564965
Toward a 3D model of human brain development for studying gene/environment interactions.Hogberg, Helena T; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Makri, Georgia; O'Driscoll, Cliona; Pamies, David; Smirnova, Lena; Wen, Zhexing; Hartung, ThomasStem cell research & therapy.2013;S424564953
Human enteroids: preclinical models of non-inflammatory diarrhea.Kovbasnjuk, Olga; Zachos, Nicholas C; In, Julie; Foulke-Abel, Jennifer; Ettayebi, Khalil; Hyser, Joseph M; Broughman, James R; Zeng, Xi-Lei; Middendorp, Sabine; de Jonge, Hugo R; Estes, Mary K; Donowitz, MarkStem cell research & therapy.2013;S324564938
Building a microphysiological skin model from induced pluripotent stem cells.Guo, Zongyou; Higgins, Claire A; Gillette, Brian M; Itoh, Munenari; Umegaki, Noriko; Gledhill, Karl; Sia, Samuel K; Christiano, Angela MStem cell research & therapy.2013;S224564920
Neurovascular unit on a chip: implications for translational applications.Alcendor, Donald J; Block 3rd, Frank E; Cliffel, David E; Daniels, John Scott; Ellacott, Kate L J; Goodwin, Cody R; Hofmeister, Lucas H; Li, Deyu; Markov, Dmitry A; May, Jody C; McCawley, Lisa J; McLaughlin, BethAnn; McLean, John A; Niswender, Kevin D; PeStem cell research & therapy.2013;S1824564885
Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.Kelly, Edward J; Wang, Zhican; Voellinger, Jenna L; Yeung, Cathy K; Shen, Danny D; Thummel, Kenneth E; Zheng, Ying; Ligresti, Giovanni; Eaton, David L; Muczynski, Kimberly A; Duffield, Jeremy S; Neumann, Thomas; Tourovskaia, Anna; Fauver, Mark; Kramer, GrStem cell research & therapy.2013;S1724564863
Annotating the structure and components of a nanoparticle formulation using computable string expressions.Thomas, Dennis G; Chikkagoudar, Satish; Chappell, Alan R; Baker, Nathan AProceedings. IEEE International Conference on Bioinformatics and Biomedicine.2012 Dec 31;889-89424533226
Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs).Fernandez, Cristina E; Achneck, Hardean E; Reichert, William M; Truskey, George ACurrent opinion in chemical engineering.2014 Feb 1;83-9024511460
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.Li, Cheri Yingjie; Stevens, Kelly R; Schwartz, Robert E; Alejandro, Brian Steven; Huang, Joanne H; Bhatia, Sangeeta NTissue engineering. Part A2014 Feb 5NULL24498910
Physical influences on stem cells.Vunjak-Novakovic, GordanaStem cell research & therapy.2013;15324476419
Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons.Pan, Dipanjan; Schirra, Carsten O; Wickline, Samuel A; Lanza, Gregory MContrast media & molecular imaging2014 Jan-Feb13-2524470291
Molecular imaging with computed tomography.Lanza, Gregory M; Pan, DipanjanContrast media & molecular imaging2014 Jan-Feb2-Jan24470289
Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration.Harper, Stacey L; Hutchison, James E; Baker, Nathan; Ostraat, Michele; Tinkle, Sally; Steevens, Jeffrey; Hoover, Mark D; Adamick, Jessica; Rajan, Krishna; Gaheen, Sharon; Cohen, Yoram; Nel, Andre; Cachau, Raul E; Tuominen, MarkComputational science & discovery20131400824454543
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer.May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, JoAnalytical chemistry.2014 Feb 18;2107-1624446877
Mapping the human toxome by systems toxicology.Bouhifd, Mounir; Hogberg, Helena T; Kleensang, Andre; Maertens, Alexandra; Zhao, Liang; Hartung, ThomasBasic & clinical pharmacology & toxicology2014 Jul24-3124443875
The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine.Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui LStem cell reviews2014 Apr177-9024425421
How multi-organ microdevices can help foster drug development.Esch, Mandy B; Smith, Alec S T; Prot, Jean-Matthieu; Oleaga, Carlota; Hickman, James J; Shuler, Michael LAdvanced drug delivery reviews.2014 Apr;158-6924412641
Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy.Li, Fengqiang; Xu, Ting; Nguyen, Duc-Huy T; Huang, Xiaolei; Chen, Christopher S; Zhou, ChaoJournal of biomedical optics.2014 Jan;1600624395588
Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles.Rangarajan, Swathi; Madden, Lauran; Bursac, NenadAnnals of biomedical engineering.2014 Jul;1391-40524366526
Physiologically relevant organs on chips.Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke PBiotechnology journal.2014 Jan;16-2724357624
Inflammatory pathways of seizure disorders.Marchi, Nicola; Granata, Tiziana; Janigro, DamirTrends in neurosciences.2014 Feb;55-6524355813
Assessing the barriers to image-guided drug delivery.Lanza, Gregory M; Moonen, Chrit; Baker Jr, James R; Chang, Esther; Cheng, Zheng; Grodzinski, Piotr; Ferrara, Katherine; Hynynen, Kullervo; Kelloff, Gary; Lee, Yong-Eun Koo; Patri, Anil K; Sept, David; Schnitzer, Jan E; Wood, Bradford J; Zhang, Miqin; ZhenWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2014 Jan-Feb14-Jan24339356
Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality.Cao, Changyong; Chan, Hon Fai; Zang, Jianfeng; Leong, Kam W; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2014 Mar 19;24339233
Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro.Cheng, Cindy S; El-Abd, Yasser; Bui, Khanh; Hyun, Young-Eun; Hughes, Rebecca Harbuck; Kraus, William E; Truskey, George AAmerican journal of physiology. Cell physiology.2014 Feb 15;24336652
Differential effects of cell adhesion, modulus and VEGFR-2 inhibition on capillary network formation in synthetic hydrogel arrays.Nguyen, Eric H; Zanotelli, Matthew R; Schwartz, Michael P; Murphy, William LBiomaterials.2014 Feb;24332391
Poised for success: implementation of sound conditioning strategies to promote endogenous protective responses to stroke in patients.McLaughlin, Bethann; Gidday, Jeff MTranslational stroke research.2013 Feb;24323191
Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems.Hong, Sungmin; Jung, Youngmee; Yen, Ringo; Chan, Hon Fai; Leong, Kam W; Truskey, George A; Zhao, XuanheLab on a chip.2014 Feb 7;24310854
Three-dimensional filamentous human diseased cardiac tissue model.Ma, Zhen; Koo, Sangmo; Finnegan, Micaela A; Loskill, Peter; Huebsch, Nathaniel; Marks, Natalie C; Conklin, Bruce R; Grigoropoulos, Costas P; Healy, Kevin EBiomaterials.2014 Feb;24268663
Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion.Grahovac, Jelena; Wells, AlanLaboratory investigation; a journal of technical methods and pathology2014 Jan31-4024247562
New immunological approaches in treating and diagnosing CNS diseases.Guo, Kathy; Janigro, DamirPharmaceutical patent analyst.2013 May;24237062
Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles.Pham, Christine T N; Thomas, Dennis G; Beiser, Julia; Mitchell, Lynne M; Huang, Jennifer L; Senpan, Angana; Hu, Grace; Gordon, Mae; Baker, Nathan A; Pan, Dipanjan; Lanza, Gregory M; Hourcade, Dennis ENanomedicine : nanotechnology, biology, and medicine2013 Nov 8NULL24211337
Development of a new method for the isolation and culture of pulmonary arterial endothelial cells from rat pulmonary arteries.Peng, Gongyong; Wen, Xing; Shi, Yu; Jiang, Yongliang; Hu, Guoping; Zhou, Yumin; Ran, PixinJournal of vascular research.2013;24192526
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption.Singh, Varsha; Yang, Jianbo; Chen, Tiane-e; Zachos, Nicholas C; Kovbasnjuk, Olga; Verkman, Alan S; Donowitz, MarkClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.2014 Jan;27-3124184676
Microfluidic device to culture 3D in vitro human capillary networks.Moya, Monica L; Alonzo, Luis F; George, Steven CMethods in molecular biology (Clifton, N.J.).2014;21-724155229
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).Itoh, Munenari; Umegaki-Arao, Noriko; Guo, Zongyou; Liu, Liang; Higgins, Claire A; Christiano, Angela MPloS one.2013;e7767324147053
Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers.Fernandez, Cristina E; Obi-onuoha, Izundu C; Wallace, Charles S; Satterwhite, Lisa L; Truskey, George A; Reichert, William MActa biomaterialia.2014 Feb;24140604
Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport.Yeung, Catherine K; Shen, Danny D; Thummel, Kenneth E; Himmelfarb, JonathanKidney international.2014 Mar;24132209
Microfabrication of human organs-on-chips.Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald ENature protocols2013 Nov2135-5724113786
Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue.Tandon, Nina; Taubman, Alanna; Cimetta, Elisa; Saccenti, Laetitia; Vunjak-Novakovic, GordanaConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.2013;6219-2324111161
Femtosecond laser-patterned nanopore arrays for surface-mediated peptide treatment.Zachman, Angela L; Hofmeister, Lucas H; Costa, Lino; Boire, Timothy C; Hwang, Yu-Shik; Hofmeister, William H; Sung, Hak-JoonNanomedicine : nanotechnology, biology, and medicine.2014 Jan;24090768
Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions.Markov, Dmitry A; Lillie, Elizabeth M; Garbett, Shawn P; McCawley, Lisa JBiomedical microdevices.2014 Feb;91-624065585
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix.Yang, Guang; Rothrauff, Benjamin B; Lin, Hang; Gottardi, Riccardo; Alexander, Peter G; Tuan, Rocky SBiomaterials.2013 Dec;9295-30624044998
The established status epilepticus trial 2013.Bleck, Thomas; Cock, Hannah; Chamberlain, James; Cloyd, James; Connor, Jason; Elm, Jordan; Fountain, Nathan; Jones, Elizabeth; Lowenstein, Daniel; Shinnar, Shlomo; Silbergleit, Robert; Treiman, David; Trinka, Eugen; Kapur, JaideepEpilepsia2013 Sep89-9224001084
A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches.Janigro, Damir; Iffland 2nd, Philip H; Marchi, Nicola; Granata, TizianaEpilepsia.2013 Sep;30-224001067
A brief account of nanoparticle contrast agents for photoacoustic imaging.Pan, Dipanjan; Kim, Benjamin; Wang, Lihong V; Lanza, Gregory MWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2013 Nov-Dec517-4323983210
Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions.Kawakami, Takahisa; Lichtnekert, Julia; Thompson, Lucas J; Karna, Prasanthi; Bouabe, Hicham; Hohl, Tobias M; Heinecke, Jay W; Ziegler, Steven F; Nelson, Peter J; Duffield, Jeremy SJournal of immunology (Baltimore, Md. : 1950).2013 Sep 15;23956422
Clear castable polyurethane elastomer for fabrication of microfluidic devices.Domansky, Karel; Leslie, Daniel C; McKinney, James; Fraser, Jacob P; Sliz, Josiah D; Hamkins-Indik, Tiama; Hamilton, Geraldine A; Bahinski, Anthony; Ingber, Donald ELab on a chip2013 Oct 73956-6423954953
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A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells.Magness, Scott T; Puthoff, Brent J; Crissey, Mary Ann; Dunn, James; Henning, Susan J; Houchen, Courtney; Kaddis, John S; Kuo, Calvin J; Li, Linheng; Lynch, John; Martin, Martin G; May, Randal; Niland, Joyce C; Olack, Barbara; Qian, Dajun; Stelzner, MatthiAmerican journal of physiology. Gastrointestinal and liver physiology.2013 Oct 15;G542-5123928185
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Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells.Crowder, Spencer W; Prasai, Dhiraj; Rath, Rutwik; Balikov, Daniel A; Bae, Hojae; Bolotin, Kirill I; Sung, Hak-JoonNanoscale.2013 May 21;4171-623592029
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Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells.Cimetta, Elisa; Sirabella, Dario; Yeager, Keith; Davidson, Kathryn; Simon, Joseph; Moon, Randall T; Vunjak-Novakovic, GordanaLab on a chip2013 Feb 7355-6423232509
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A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.Huh, Dongeun; Leslie, Daniel C; Matthews, Benjamin D; Fraser, Jacob P; Jurek, Samuel; Hamilton, Geraldine A; Thorneloe, Kevin S; McAlexander, Michael Allen; Ingber, Donald EScience translational medicine2012 Nov 7159ra14723136042
Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films.Zachman, Angela L; Page, Jonathan M; Prabhakar, Gayathri; Guelcher, Scott A; Sung, Hak-JoonActa biomaterialia.2013 Feb;4964-7523128157
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Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide.Zhang, Lingbo; Wang, Kezheng; Zhao, Falin; Hu, Weiping; Chen, Junjie; Lanza, Gregory M; Shen, Baozhong; Zhang, BinPloS one2012e4625523029451
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Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles.Zhou, Hui-Fang; Yan, Huimin; Senpan, Angana; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T NBiomaterials2012 Nov8632-4022922023
Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.Hu, Lingzhi; Chen, Junjie; Yang, Xiaoxia; Caruthers, Shelton D; Lanza, Gregory M; Wickline, Samuel AMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine2012 Aug 2222915328
A mini-microscope for in situ monitoring of cells.Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, AliLab on a chip2012 Oct 213976-8222911426
The contribution of cellular mechanotransduction to cardiomyocyte form and function.Sheehy, Sean P; Grosberg, Anna; Parker, Kevin KitBiomechanics and modeling in mechanobiology2012 Nov1227-3922772714
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Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug.Pan, Dipanjan; Sanyal, Nibedita; Schmieder, Anne H; Senpan, Angana; Kim, Benjamin; Yang, Xiaoxia; Hu, Grace; Allen, John S; Gross, Richard W; Wickline, Samuel A; Lanza, Gregory MNanomedicine (London, England)2012 Oct1507-1922709347
Adaptive clinical trials: a partial remedy for the therapeutic misconception?Meurer, William J; Lewis, Roger J; Berry, Donald AJAMA : the journal of the American Medical Association2012 Jun 132377-822692168
Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier.Janigro, DamirEpilepsia.2012 Jun;26-3422612806
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Muscle on a chip: in vitro contractility assays for smooth and striated muscle.Grosberg, Anna; Nesmith, Alexander P; Goss, Josue A; Brigham, Mark D; McCain, Megan L; Parker, Kevin KitJournal of pharmacological and toxicological methods2012 May-Jun126-3522521339
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An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging.Pan, Dipanjan; Schirra, Carsten O; Senpan, Angana; Schmieder, Anne H; Stacy, Allen J; Roessl, Ewald; Thran, Axel; Wickline, Samuel A; Proska, Roland; Lanza, Gregory MACS nano2012 Apr 243364-7022385324
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Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces.Pham, Christine T N; Mitchell, Lynne M; Huang, Jennifer L; Lubniewski, Christopher M; Schall, Otto F; Killgore, J Kendall; Pan, Dipanjan; Wickline, Samuel A; Lanza, Gregory M; Hourcade, Dennis EThe Journal of biological chemistry2011 Jan 7123-3021047788
Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of *-catenin signaling.Cimetta, Elisa; Cannizzaro, Christopher; James, Richard; Biechele, Travis; Moon, Randall T; Elvassore, Nicola; Vunjak-Novakovic, GordanaLab on a chip.2010 Dec 7;3277-8320936235
Biophysics and dynamics of natural and engineered stem cell microenvironments.Keung, Albert J; Healy, Kevin E; Kumar, Sanjay; Schaffer, David VWiley interdisciplinary reviews. Systems biology and medicine2010 Jan-Feb49-6420836010
Transporters in drug-refractory epilepsy: clinical significance.Marchi, N; Gonzalez-Martinez, J; Nguyen, M-T; Granata, T; Janigro, DClinical pharmacology and therapeutics.2010 Jan;20019694