Disclaimer: The information in these pages are meant to provide general guidance. Instructions and procedures outlined in the Funding Opportunity Announcement and SF424 Application Guide take precedence over any information provided and should be referred to for complete and comprehensive directions.

Sample Applications

Always follow the Funding Opportunity Announcement and SF424 Application Guide's instructions for application format. Time has passed since these grantees applied, and the samples may not reflect the latest format or rules.

The text of these applications is copyrighted. You may use it only for nonprofit educational purposes provided the document remains unchanged and the PI, the grantee organization, and NIH are credited.

Note on Section 508 Conformance and Accessibility: We have reformatted these samples to improve accessibility for people with disabilities and users of assistive technology. If you have trouble accessing the content, please contact NIH staff at PioneerAwards@mail.nih.gov.

Competition Year PI Name Institution Name Title






Control of the Neonatal Septisome and Hydrocephalus in Sub-Saharan Africa


Thank you to the PIs and institutions for allowing us to publicly post their Pioneer Award applications. We are grateful for their willingness to share and their assistance with this guide.



More questions? Contact us at PioneerAwards@mail.nih.gov.

This page last reviewed on July 10, 2020