We Accelerate Discovery

You are here


Selected Scientific Reviews (Bold=NDC PI)


Nanomedicine Development Center for Optical Control of Biological Function

Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY (2013) Optical control of metabotropic glutamate receptors. Nat Neurosci. 2013 Apr;16 (4):507. Exit Disclaimer

Chambers JJ and Kramer, RH (2011) Editors: Photosensitive Molecules for Controlling Biological Function. Humana Press. Exit Disclaimer

Gorostiza P and Isacoff, EY (2011) Photoswitchable ligand‐gated ion channels. In Photosensitive Molecules for Controlling Biological Function. Ed. J. Chambers. Humana Press. pp. 267‐285. Exit Disclaimer

Janovjak H and Isacoff, EY (2011) Structure‐based Design of Light‐Controlled Proteins. In Photosensitive Molecules for Controlling Biological Function. Ed. J. Chambers. Humana Press.pp. 233‐266. Exit Disclaimer

Szobota  S and Isacoff, EY (2010) Optical Control of Neuronal Activity. Ann. Rev. Biophys. 39: 329-348. Exit Disclaimer

Reiner, Andreas; Isacoff, Ehud Y (2013) The Brain Prize 2013: the optogenetics revolution. Trends Neurosci. 2013 Oct;36(10):557-60. Exit Disclaimer

Reiner, Andreas; Isacoff, Ehud Y (2014) Photoswitching of cell surface receptors using tethered ligands. Methods Mol Biol. 2014;1148:45-68. Exit Disclaimer

Fortin DL, Dunn TW, Kramer RH (2011) Engineering light‐regulated ion channels. Cold Spring Harb. Protoc. 2011, 579‐85. PMID: 21632787. Exit Disclaimer

Fehrentz T, Schönberger M, and Trauner D (2011) Optochemical Genetics. Angew. Chem. Int. Ed. 16, 12156‐82. PMID: 22109984. Exit Disclaimer


Nanomedicine Center for Nucleoprotein Machines

Deriano, Ludovic; Roth, David B (2013) Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage. Annu Rev Genet. 2013;47:433-55. Exit Disclaimer

Tong S, Fine EJ, Lin Y, Cradick TJ, Bao G. (2014) Nanomedicine: tiny particles and machines give huge gains. Ann Biomed Eng. 2014 Feb;42(2):243-59. Exit Disclaimer

Lindsay CR, Roth DB. (2014) An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases. Methods Mol Biol. 2014;1114:353-69. Exit Disclaimer

Lin Y, Cradick TJ, Bao G. (2014) Designing and testing the activities of TAL effector nucleases. Methods Mol Biol. 2014;1114:203-19. Exit Disclaimer

Fine EJ, Cradick TJ, Bao G. (2014) Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models. Methods Mol Biol. 2014;1114:371-83. Exit Disclaimer

Bao G, Mitragotri S and Tong S (2013) Multi-functional nanoparticles for drug delivery and molecular imaging. Annu. Rev. Biomed. Eng., 15: 253-282. Exit Disclaimer

Tong S, Cradick TJ, Ma Y, Dai Z, Bao G (2012) Engineering imaging probes and molecular machines for nanomedicine. Science China Life Sciences, 55: 843-861. Exit Disclaimer

Smith AM and Nie SM (2010) Semiconductor nanocrystals: structure, properties, and bandgap engineering. Acc. Chem. Res. 43, 190-200. Exit Disclaimer

Smith AM, Wen MM and Nie SM (2010) Imaging dynamic cellular events with quantum dots – the bright future. The Biochemist, 32:12-17. Exit Disclaimer


Center for Protein Folding

Ruparelia, Aarti; Pearn, Matthew L; Mobley, William C (2013) Aging and intellectual disability: Insights from mouse models of down syndrome. Dev Disabil Res Rev. 2013 Aug;18(1):43-50. Exit Disclaimer

Shahmoradian, SH, Galaz-Montoya, JG, Schmid, MF, Cong, Y, Ma, B, Spiess, C, Frydman, J, Ludtke, SJ, & Chiu, W (2013) TRiC's tricks inhibit huntingtin aggregation Elife. 2013 Jul 9;2:e00710. Exit Disclaimer

Sahl, Steffen J; Moerner, W E (2013) Super-resolution fluorescence imaging with single molecules. Curr Opin Struct Biol. 2013 Oct;23(5):778-87. Exit Disclaimer

Sontag, Emily M; Vonk, Willianne I M; Frydman, Judith (2014) Sorting out the trash: the spatial nature of eukaryotic protein quality control. Curr Opin Cell Biol. 2014 Feb;26:139-46. Exit Disclaimer

Jonasch E, Futreal PA, Davis IJ, Bailey ST, Kim WY, Brugarolas J, Giaccia AJ, Kurban G, Pause A, Frydman J, Zurita AJ, Rini BI, Sharma P, Atkins MB, Walker CL, Rathmell WK (2012) State of the science: an update on renal cell carcinoma. Mol Cancer Res. 10(7):859-880. Exit Disclaimer

Weissmiller AM, Wu C. (2012) Current advances in using neurotrophic factors to treat neurodegenerative disorders. Transl Neurodegener 1(1):14. Exit Disclaimer


Nanomedicine Center for Mechanobiology Directing the Immune Response

Milone, Michael C; Kam, Lance C (2013) Investigative and clinical applications of synthetic immune synapses. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Jan-Feb;5(1):75-85. Exit Disclaimer

Kam, L C; Shen, K; Dustin, M L (2013) Micro- and nanoscale engineering of cell signaling. Annu Rev Biomed Eng. 2013;15:305-26. Exit Disclaimer

Dutta, Debjit; Kam, Lance C (2014) Micropatterned, multicomponent supported lipid bilayers for cellular systems. Methods Cell Biol. 2014;120:53-67. Exit Disclaimer

Milone MC, and Kam LC (2013) Investigative and Clinical Applications of Synthetic Immune Synapses, WIREs: Nanomedicine and Nanobiotechnology. 5(1):75-85. Exit Disclaimer

Kam LC, Shen K, and Dustin ML. (2013) Micro- and Nanoscale Engineering of Cell Signaling. Annual Review of Biomedical Engineering, 15: 305-326. Exit Disclaimer

Poultney CS, Greenfield A, Bonneau R (2012) Integrated inference and analysis of regulatory networks from multi-level measurements. Methods Cell Biol. 110:19-56. Exit Disclaimer

Wolfenson H, Lavelin I, and Geiger B (2013) Dynamic regulation of the structure and functions of integrin adhesions. Developmental Cell 24: 447-458. Exit Disclaimer


Cellular Control: Synthetic Signaling/Motility (the “Cell Propulsion” laboratory)

Fischbach, Michael A; Bluestone, Jeffrey A; Lim, Wendell A (2013) Cell-based therapeutics: the next pillar of medicine. Sci Transl Med. 2013 Apr 3;5(179):179ps7. Exit Disclaimer

Lim WA. (2010) Designing customized cell signalling circuits. Nat Rev Mol Cell Biol. Jun;11(6):393-403. Exit Disclaimer

Fletcher DA, Mullins RD (2010) Cell mechanics and the cytoskeleton. Nature. Jan 28;463(7280):485-92. Review. Exit Disclaimer

Toettcher JE, Voigt CA, Weiner OD, Lim WA (2011) The promise of optogenetics in cell biology: interrogating molecular circuits in space and time. Nat Methods. 8(1): 35-8. Exit Disclaimer

Bashor CJ, Horwitz AA, Peisajovich SG, Lim WA (2010) Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems. Annu Rev Biophys. Jun 9;39:515-37. Exit Disclaimer


Phi29 DNA-Packaging Motor for Nanomedicine

Haque, Farzin; Li, Jinghong; Wu, Hai-Chen; Liang, Xing-Jie; Guo, Peixuan (2013) Solid-State and Biological Nanopore for Real-Time Sensing of Single Chemical and Sequencing of DNA. Nano Today. 2013 Feb;8(1):56-74. Exit Disclaimer

Guo P, Hague F, Hallahan B, Reif R, Li H (2012) Uniqueness, advantages, challenges, solutions, and perspectives in therapeurics applying RNA nanotechnology. Nucleic Acid Ther. 22:226-245. Exit Disclaimer

Shu Y, Cinier M, Shu D, Guo P (2011) Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells. Methods 54:204-214. Exit Disclaimer

Guo P (2010) The emerging field of RNA nanotechnology. Nat Nanotechnol. 5:833-842. Exit Disclaimer


National Center for Design of Biomimetic Nanoconductors

Bricarello DA, Patel MA, Parikh AN (2012) Inhibiting host-pathogen interactions using membrane-based nanostructures. Trends Biotechnol. 30:323-330. Exit Disclaimer

Baca HK, Carnes EC, Ashley CE, Lopez DM, Douthit C, Karlin S, Brinker J (2011) Cell-directed-assembly: Directing the formation of nano/bio interfaces and architectures with living cells. Biochim Biophys Acta. 1810:259-267. Exit Disclaimer

Center for Cell Control

Valamehr B, Tsutsui H, Ho CM, Wu H (2011) Developing defined culture systems for human pluripotent stem cells. Regen Med. 6:623-634. Exit Disclaimer

Sherman MH, Bassing CH, Teitell MA (2011) Regulation of cell differentiation by the DNA damage response. Trends Cell Biol. 21:312-319. Exit Disclaimer

Liu SY, Sanchez DJ, Cheng G (2011) New developments in the induction and antiviral effectors of type I interferon. Curr Opin Immunol. 23:57-64. Exit Disclaimer

Wei F, Lillehoj PB, Ho CM (2010) DNA diagnostics: nanotechnology-enhanced electrochemical detection of nucleic acids. Pediatr Res. 67:458-468. Exit Disclaimer

Up to Top