Diagram of an integrated multichannel imaging system for intraoperative cancer detection and image-guided surgery

Contrast-enhanced and image-guided surgery of lung cancer

For high sensitivity and specificity in tumor detection, this system is equipped with 4 input channels, shown in 4 panels: (i) a high-definition video channel for anatomical color imaging; (ii) a laser light channel for real-time tracking of the laser beam position; (iii) a near-infrared (NIR) channel for wide-field imaging of wavelength-shifted contrast signals; and (iv) a spectroscopic channel for recording wavelength-resolved spectra of the contrast agents.