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Funded Research

 

 

 
Studies to evaluate cellular heterogeneity using transcriptional profiling of single cells (U01)
RFA-RM-11-013
PI Name Institution Name Title
EBERWINE, JAMES H (contact)
KIM, JUNHYONG
UNIVERSITY OF PENNSYLVANIA Role of Single Cell mRNA Variation in Systems Associated Electrically Excitable C
KNOWLES, JAMES A (contact)
CHOW, ROBERT HSIU-PING
UNIVERSITY OF SOUTHERN CALIFORNIA Evaluation of Cellular Heterogeneity Using Patchclamp and RNA-Seq of Single Cells
ZHANG, KUN UNIVERSITY OF CALIFORNIA SAN DIEGO Single-cell sequencing and in situ mapping of RNA transcripts in human brains

 

Exceptionally Innovative Tools and Technologies for Single Cell Analysis (R21)
RFA-RM-11-014

PI Name Institution Name Title
COVERT, MARKUS W STANFORD UNIVERSITY New methods for monitoring the immune system, in individual cells and in vivo
DENISENKO, OLEG N UNIVERSITY OF WASHINGTON Single cell analysis of chromatin changes at individual genes
KARTALOV, EMIL P UNIVERSITY OF SOUTHERN CALIFORNIA High-Throughput Single-Cell-PCR Technique for Tissue Analysis of Genetic Heteroge
KIRSCHNER, MARC WALLACE HARVARD UNIVERSITY (MEDICAL SCHOOL) A high-throughput method for simultaneous profiling of mRNA and protein levels in
KONRY, TALI TANIA MASSACHUSETTS GENERAL HOSPITAL Development of Microfluidic Nano-Liter Platform for Single Cell Dynamic Monitorin
LEVY, MATTHEW (contact)
SNAPP, ERIK L.
ALBERT EINSTEIN COL OF MED YESHIVA UNIV Fluorescent probes for quantitation of secretory protein levels in single cells
LOVE, JOHN CHRISTOPHER MASSACHUSETTS INSTITUTE OF TECHNOLOGY Highly Multiplexed Single-cell Transcript Analysis Using DNA-barcoded Nanowells
MELDRUM, DEIRDRE R. ARIZONA STATE UNIVERSITY-TEMPE CAMPUS In Situ Single Cell Laser Lysis and Downstream qRT-PCR Profiling
MIZUTANI, CLAUDIA (contact)
GUO, WEIHONG
SOUSA-NEVES, RUI
CASE WESTERN RESERVE UNIVERSITY Real-time visualization of neural stem cell transcriptome
MURRAY, KERMIT KING LOUISIANA STATE UNIV A&M COL BATON ROUGE Nanoscale Laser Ablation Capture Mass Spectrometry for Single Cell Proteomics
NAVIN, NICHOLAS UNIVERSITY OF TEXAS MD ANDERSON CAN CTR Developing a whole-genome sequencing method for single human cells
NEU, COREY P PURDUE UNIVERSITY WEST LAFAYETTE Combined Biophysical and Biochemical Study of Single Cells
RESHETNYAK, YANA K. (contact)
ANDREEV, OLEG A
UNIVERSITY OF RHODE ISLAND Mapping pH at the surface of individual cell
SIMS, PETER ALAN COLUMBIA UNIVERSITY HEALTH SCIENCES Multiplexed, Single Molecule Protein Identification for Single Cell Proteomics
WANG, YINGXIAO UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN A Systematic Approach to Engineer Fyn Kinase Biosensor

 

Accelerating the Integration and Translation of Technologies to Characterize Biological Processes at the Single Cell Level (R01)
RFA-RM-11-015

PI Name Institution Name Title
BAO, ZHIRONG SLOAN-KETTERING INSTITUTE FOR CANCER RES An integrated system to monitor complex tissues at single-cell resolution
BOYDEN, EDWARD S. (contact)
FOREST, CRAIG
ZENG, HONGKUI
MASSACHUSETTS INSTITUTE OF TECHNOLOGY High-throughput robotic analysis of integrated neuronal phenotypes
BUSHKIN, YURI (contact)
GENNARO, MARIA LAURA
TYAGI, SANJAY
UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL Rapid Analysis of Single T Cell Immunity Signatures in Tuberculosis
CAI, LONG (contact)
SOMLO, GEORGE
CALIFORNIA INSTITUTE OF TECHNOLOGY Multiplex RNA imaging in single cells by superresolution microscopy& barcode FISH
GERDES, MICHAEL (contact)
COFFEY, ROBERT J.
SHAIKH, KASHAN
GENERAL ELECTRIC GLOBAL RESEARCH CTR Validation of a single cell multiplexed in-situ biomarker analysis platform for p
LOVE, JOHN CHRISTOPHER MASSACHUSETTS INSTITUTE OF TECHNOLOGY Nanowell-based single-cell technology for characterizing clinical samples ex vivo
MAYFORD, MARK R. SCRIPPS RESEARCH INSTITUTE Activity Based Tagging of Neurons
VARADARAJAN, NAVIN (contact)
COOPER, LAURENCE J.N.
UNIVERSITY OF HOUSTON Quantitative single-cell biomarkers of T-cells to optimize tumor immunotherapy
WIRTZ, DENIS JOHNS HOPKINS UNIVERSITY Single-cell phenotyping for therapeutic stratification in pancreatic cancer

 

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