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NIH Director’s Transformative Research Awards (749)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Small-molecule axon-polarization studies enabled by a shear-free microfluidic gradient generator.Xu, Hui; Ferreira, Meghaan M; Heilshorn, Sarah CLab on a chip2014 Jun 212047-5624781157
Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype.Boehler, R M; Kuo, R; Shin, S; Goodman, A G; Pilecki, M A; Leonard, J N; Shea, L DBiotechnology and bioengineering2014 Jun1210-2124375008
Development and evaluation of SYBR Green-I based quantitative PCR assays for herpes simplex virus type 1 whole transcriptome analysis.Garvey, Cathryn E; McGowin, Chris L; Foster, Timothy PJournal of virological methods2014 Jun101-1124607486
Comprehensive analysis of RNA-protein interactions by high-throughput sequencing-RNA affinity profiling.Tome, Jacob M; Ozer, Abdullah; Pagano, John M; Gheba, Dan; Schroth, Gary P; Lis, John TNature methods2014 Jun683-824809628
Stem cells as vehicles for youthful regeneration of aged tissues.Rando, Thomas A; Wyss-Coray, TonyThe journals of gerontology. Series A, Biological sciences and medical sciences2014 JunS39-4224833585
The Lipid Kinase PIP5K1C Regulates Pain Signaling and Sensitization.Wright, Brittany D; Loo, Lipin; Street, Sarah E; Ma, Anqi; Taylor-Blake, Bonnie; Stashko, Michael A; Jin, Jian; Janzen, William P; Frye, Stephen V; Zylka, Mark JNeuron2014 May 21836-4724853942
Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data.Peng, Xinxia; Pipes, Lenore; Xiong, Hao; Green, Richard R; Jones, Daniel C; Ruzzo, Walter L; Schroth, Gary P; Mason, Christopher E; Palermo, Robert E; Katze, Michael GJournal of medical primatology2014 May 8NULL24810475
Structurally distinct ca(2+) signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility.Chung, Jean-Ju; Shim, Sang-Hee; Everley, Robert A; Gygi, Steven P; Zhuang, Xiaowei; Clapham, David ECell2014 May 8808-2224813608
Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors.Motz, Gregory T; Santoro, Stephen P; Wang, Li-Ping; Garrabrant, Tom; Lastra, Ricardo R; Hagemann, Ian S; Lal, Priti; Feldman, Michael D; Benencia, Fabian; Coukos, GeorgeNature medicine2014 May 4NULL24793239
Molecular-level functional magnetic resonance imaging of dopaminergic signaling.Lee, Taekwan; Cai, Lili X; Lelyveld, Victor S; Hai, Aviad; Jasanoff, AlanScience (New York, N.Y.)2014 May 2533-524786083
Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes.van Schaijk, Ben C L; Kumar, T R Santha; Vos, Martijn W; Richman, Adam; van Gemert, Geert-Jan; Li, Tao; Eappen, Abraham G; Williamson, Kim C; Morahan, Belinda J; Fishbaugher, Matt; Kennedy, Mark; Camargo, Nelly; Khan, Shahid M; Janse, Chris J; Sim, Kim LeEukaryotic cell2014 May550-924297444
C4d deposits on the surface of RBCs in trauma patients and interferes with their function.Muroya, Takashi; Kannan, Lakshmi; Ghiran, Ionita C; Shevkoplyas, Sergey S; Paz, Ziv; Tsokos, Maria; Dalle Lucca, Jurandir J; Shapiro, Nathan I; Tsokos, George CCritical care medicine2014 Maye364-7224448198
Overexpression of diacylglycerol kinase ýý enhances G*q-coupled G protein-coupled receptor signaling.Rittiner, Joseph E; Brings, Victoria E; Zylka, Mark JMolecular pharmacology2014 May800-1024608858
One-pot Synthesis of Elastin-like Polypeptide Hydrogels with Grafted VEGF-Mimetic Peptides.Cai, Lei; Dinh, Cong B; Heilshorn, Sarah CBiomaterials science2014 May 1757-76524729868
T-cell and NK-cell infiltration into solid tumors: a key limiting factor for efficacious cancer immunotherapy.Melero, Ignacio; Rouzaut, Ana; Motz, Greg T; Coukos, GeorgeCancer discovery2014 May522-624795012
Concise review: MicroRNA function in multipotent mesenchymal stromal cells.Clark, Elizabeth A; Kalomoiris, Stefanos; Nolta, Jan A; Fierro, Fernando AStem cells (Dayton, Ohio)2014 May1074-8224860868
The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification.Pukkila-Worley, Read; Feinbaum, Rhonda L; McEwan, Deborah L; Conery, Annie L; Ausubel, Frederick MPLoS pathogens2014 Maye100414324875643
Induced neuronal reprogramming.Ang, Cheen Euong; Wernig, MariusThe Journal of comparative neurology2014 Apr 27NULL24771471
Induction of retinal progenitors and neurons from mammalian Muller glia under defined conditions.Zhao, Jack Jiagang; Ouyang, Hong; Luo, Jing; Patel, Sherrina; Xue, Yuanchao; Quach, John; Sfeir, Nicole; Zhang, Meixia; Fu, Xiangdong; Ding, Sheng; Chen, Shaochen; Zhang, KangThe Journal of biological chemistry2014 Apr 2511945-5124523410
Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2.Gavrish, Ekaterina; Sit, Clarissa S; Cao, Shugeng; Kandror, Olga; Spoering, Amy; Peoples, Aaron; Ling, Losee; Fetterman, Ashley; Hughes, Dallas; Bissell, Anthony; Torrey, Heather; Akopian, Tatos; Mueller, Andreas; Epstein, Slava; Goldberg, Alfred; Clardy,Chemistry & biology2014 Apr 24509-1824684906
Alemtuzumab Therapy for Leukemic Cutaneous T-Cell Lymphoma: Diffuse Erythema as a Positive Predictor of Complete Remission.Watanabe, Rei; Teague, Jessica E; Fisher, David C; Kupper, Thomas S; Clark, Rachael AJAMA dermatology2014 Apr 23NULL24760312
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis.Walker, A K; Rivera, P D; Wang, Q; Chuang, J-C; Tran, S; Osborne-Lawrence, S; Estill, S J; Starwalt, R; Huntington, P; Morlock, L; Naidoo, J; Williams, N S; Ready, J M; Eisch, A J; Pieper, A A; Zigman, J MMolecular psychiatry2014 Apr 22NULL24751964
Magnetic nanosensors optimized for rapid and reversible self-assembly.Rodriguez, Elisenda; Lelyveld, Victor S; Atanasijevic, Tatjana; Okada, Satoshi; Jasanoff, AlanChemical communications (Cambridge, England)2014 Apr 73595-824566735
Polyhedra self-assembled from DNA tripods and characterized with 3D DNA-PAINT.Iinuma, Ryosuke; Ke, Yonggang; Jungmann, Ralf; Schlichthaerle, Thomas; Woehrstein, Johannes B; Yin, PengScience (New York, N.Y.)2014 Apr 465-924625926
Extracellular MicroRNAs Activate Nociceptor Neurons to Elicit Pain via TLR7 and TRPA1.Park, Chul-Kyu; Xu, Zhen-Zhong; Berta, Temugin; Han, Qingjian; Chen, Gang; Liu, Xing-Jun; Ji, Ru-RongNeuron2014 Apr 247-5424698267
Designing ECM-mimetic materials using protein engineering.Cai, Lei; Heilshorn, Sarah CActa biomaterialia2014 Apr1751-176024365704
A computational model of the response of adherent cells to stretch and changes in substrate stiffness.Parameswaran, Harikrishnan; Lutchen, Kenneth R; Suki, BelaJournal of applied physiology (Bethesda, Md. : 1985)2014 Apr 1825-3424408996
Modeling the dynamical effects of anesthesia on brain circuits.Ching, Shinung; Brown, Emery NCurrent opinion in neurobiology2014 Apr116-2224457211
Ectopic transplantation sites for cell-based therapy.DeWard, Aaron D; Komori, Junji; Lagasse, EricCurrent opinion in organ transplantation2014 Apr169-7424480968
Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model.Li, Chunsheng; Chacko, Ann-Marie; Hu, Jia; Hasegawa, Kosei; Swails, Jennifer; Grasso, Luigi; El-Deiry, Wafik S; Nicolaides, Nicholas; Muzykantov, Vladimir R; Divgi, Chaitanya R; Coukos, GeorgeCancer biology & therapy2014 Apr443-5124553243
High-throughput binding characterization of RNA aptamer selections using a microplate-based multiplex microcolumn device.Szeto, Kylan; Reinholt, Sarah J; Duarte, Fabiana M; Pagano, John M; Ozer, Abdullah; Yao, Li; Lis, John T; Craighead, Harold GAnalytical and bioanalytical chemistry2014 Apr2727-3224553662
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors.Crotti, Andrea; Benner, Christopher; Kerman, Bilal E; Gosselin, David; Lagier-Tourenne, Clotilde; Zuccato, Chiara; Cattaneo, Elena; Gage, Fred H; Cleveland, Don W; Glass, Christopher KNature neuroscience2014 Apr513-2124584051
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition.Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, AlanBreast cancer research and treatment2014 Apr551-6024610032
Development and function of human innate immune cells in a humanized mouse model.Rongvaux, Anthony; Willinger, Tim; Martinek, Jan; Strowig, Till; Gearty, Sofia V; Teichmann, Lino L; Saito, Yasuyuki; Marches, Florentina; Halene, Stephanie; Palucka, A Karolina; Manz, Markus G; Flavell, Richard ANature biotechnology2014 Apr364-7224633240
Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy.Schain, Aaron J; Hill, Robert A; Grutzendler, JaimeNature medicine2014 Apr443-924681598
HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism.Weyn-Vanhentenryck, Sebastien M; Mele, Aldo; Yan, Qinghong; Sun, Shuying; Farny, Natalie; Zhang, Zuo; Xue, Chenghai; Herre, Margaret; Silver, Pamela A; Zhang, Michael Q; Krainer, Adrian R; Darnell, Robert B; Zhang, ChaolinCell reports2014 Mar 271139-5224613350
Engineering Liver.Griffith, Linda G; Wells, Alan; Stolz, Donna BeerHepatology (Baltimore, Md.)2014 Mar 26NULL24668880
Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers.Wang, Jinpeng; Gong, Qiang; Maheshwari, Nupur; Eisenstein, Michael; Arcila, Mary Luz; Kosik, Kenneth S; Soh, H TomAngewandte Chemie (International ed. in English)2014 Mar 18NULL24644057
Human retinal progenitor cell transplantation preserves vision.Luo, Jing; Baranov, Petr; Patel, Sherrina; Ouyang, Hong; Quach, John; Wu, Frances; Qiu, Austin; Luo, Hongrong; Hicks, Caroline; Zeng, Jing; Zhu, Jing; Lu, Jessica; Sfeir, Nicole; Wen, Cindy; Zhang, Meixia; Reade, Victoria; Patel, Sara; Sinden, John; Sun, The Journal of biological chemistry2014 Mar 76362-7124407289
Common genetic variants modulate pathogen-sensing responses in human dendritic cells.Lee, Mark N; Ye, Chun; Villani, Alexandra-Chloe; Raj, Towfique; Li, Weibo; Eisenhaure, Thomas M; Imboywa, Selina H; Chipendo, Portia I; Ran, F Ann; Slowikowski, Kamil; Ward, Lucas D; Raddassi, Khadir; McCabe, Cristin; Lee, Michelle H; Frohlich, Irene Y; HScience (New York, N.Y.)2014 Mar 7124698024604203
Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation.Grutzendler, Jaime; Murikinati, Sasidhar; Hiner, Bennett; Ji, Lingling; Lam, Carson K; Yoo, Taehwan; Gupta, Shobhana; Hafler, Brian P; Adelman, Ron A; Yuan, Peng; Rodriguez, GuadalupeScience translational medicine2014 Mar 5226ra3124598589
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-* secretion.Berta, Temugin; Park, Chul-Kyu; Xu, Zhen-Zhong; Xie, Ruo-Gang; Liu, Tong; Lu, Ning; Liu, Yen-Chin; Ji, Ru-RongThe Journal of clinical investigation2014 Mar 31173-8624531553
Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury.Blaya, Meghan O; Bramlett, Helen M; Naidoo, Jacinth; Pieper, Andrew A; Dietrich, W DaltonJournal of neurotrauma2014 Mar 1476-8624070637
Clinical translation of stem cells: insight for cartilage therapies.Lee, Jennifer K; Responte, Donald J; Cissell, Derek D; Hu, Jerry C; Nolta, Jan A; Athanasiou, Kyriacos ACritical reviews in biotechnology2014 Mar89-10024083452
Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements.Wang, Feng; Wang, Hui; Tuan, Han-Fang; Nguyen, Duy H; Sun, Vincent; Keser, Vafa; Bowne, Sara J; Sullivan, Lori S; Luo, Hongrong; Zhao, Ling; Wang, Xia; Zaneveld, Jacques E; Salvo, Jason S; Siddiqui, Sorath; Mao, Louise; Wheaton, Dianna K; Birch, David G; Human genetics2014 Mar331-4524154662
A screen for and validation of prodrug antimicrobials.Fleck, Laura E; North, E Jeffrey; Lee, Richard E; Mulcahy, Lawrence R; Casadei, Gabriele; Lewis, KimAntimicrobial agents and chemotherapy2014 Mar1410-924342644
Pluripotent stem cell-derived hepatocyte-like cells.Schwartz, R E; Fleming, H E; Khetani, S R; Bhatia, S NBiotechnology advances2014 Mar-Apr504-1324440487
Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT.Jungmann, Ralf; Avendano, Maier S; Woehrstein, Johannes B; Dai, Mingjie; Shih, William M; Yin, PengNature methods2014 Mar313-824487583
Independent optical excitation of distinct neural populations.Klapoetke, Nathan C; Murata, Yasunobu; Kim, Sung Soo; Pulver, Stefan R; Birdsey-Benson, Amanda; Cho, Yong Ku; Morimoto, Tania K; Chuong, Amy S; Carpenter, Eric J; Tian, Zhijian; Wang, Jun; Xie, Yinlong; Yan, Zhixiang; Zhang, Yong; Chow, Brian Y; Surek, BaNature methods2014 Mar338-4624509633
Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin.Chacko, Ann-Marie; Li, Chunsheng; Nayak, Madhura; Mikitsh, John L; Hu, Jia; Hou, Catherine; Grasso, Luigi; Nicolaides, Nicholas C; Muzykantov, Vladimir R; Divgi, Chaitanya R; Coukos, GeorgeJournal of nuclear medicine : official publication, Society of Nuclear Medicine2014 Mar500-724525208
New role for the mitochondrial peptide humanin: protective agent against chemotherapy-induced side effects.Cohen, PinchasJournal of the National Cancer Institute2014 Mardju00624586106
Calibration-free absolute quantification of particle concentration by statistical analyses of photoacoustic signals in vivo.Zhou, Yong; Yao, Junjie; Maslov, Konstantin I; Wang, Lihong VJournal of biomedical optics2014 Mar3700124589987
Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time.Lai, Puxiang; Xu, Xiao; Wang, Lihong VJournal of biomedical optics2014 Mar3500224604534
CAR T cells for solid tumors: armed and ready to go?Kakarla, Sunitha; Gottschalk, StephenCancer journal (Sudbury, Mass.)2014 Mar-Apr151-524667962
A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions.Doran, Todd M; Kodadek, ThomasACS chemical biology2014 Feb 21339-4624245981
A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer.Tian, Yuan; Simanshu, Dhirendra K; Ma, Jin-Biao; Park, Jong-Eun; Heo, Inha; Kim, V Narry; Patel, Dinshaw JMolecular cell2014 Feb 20606-1624486018
Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness.Sheahan, Timothy; Imanaka, Naoko; Marukian, Svetlana; Dorner, Marcus; Liu, Peng; Ploss, Alexander; Rice, Charles MCell host & microbe2014 Feb 12190-20224528865
P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases.Pieper, Andrew A; McKnight, Steven L; Ready, Joseph MChemical Society reviews2014 Feb 11NULL24514864
Presentation of BMP-2 mimicking peptides in 3D hydrogels directs cell fate commitment in osteoblasts and mesenchymal stem cells.Madl, Christopher M; Mehta, Manav; Duda, Georg N; Heilshorn, Sarah C; Mooney, David JBiomacromolecules2014 Feb 10445-5524400664
Mismatches improve the performance of strand-displacement nucleic Acid circuits.Jiang, Yu Sherry; Bhadra, Sanchita; Li, Bingling; Ellington, Andrew DAngewandte Chemie (International ed. in English)2014 Feb 101845-824402831
Independent optical excitation of distinct neural populations.Klapoetke, Nathan C; Murata, Yasunobu; Kim, Sung Soo; Pulver, Stefan R; Birdsey-Benson, Amanda; Cho, Yong Ku; Morimoto, Tania K; Chuong, Amy S; Carpenter, Eric J; Tian, Zhijian; Wang, Jun; Xie, Yinlong; Yan, Zhixiang; Zhang, Yong; Chow, Brian Y; Surek, BaNature methods2014 Feb 9NULL24509633
In vivo discovery of immunotherapy targets in the tumour microenvironment.Zhou, Penghui; Shaffer, Donald R; Alvarez Arias, Diana A; Nakazaki, Yukoh; Pos, Wouter; Torres, Alexis J; Cremasco, Viviana; Dougan, Stephanie K; Cowley, Glenn S; Elpek, Kutlu; Brogdon, Jennifer; Lamb, John; Turley, Shannon J; Ploegh, Hidde L; Root, DavidNature2014 Feb 652-724476824
Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.Beste, Michael T; Pfaffle-Doyle, Nicole; Prentice, Emily A; Morris, Stephanie N; Lauffenburger, Douglas A; Isaacson, Keith B; Griffith, Linda GScience translational medicine2014 Feb 5222ra1624500404
Interconnected network motifs control podocyte morphology and kidney function.Azeloglu, Evren U; Hardy, Simon V; Eungdamrong, Narat John; Chen, Yibang; Jayaraman, Gomathi; Chuang, Peter Y; Fang, Wei; Xiong, Huabao; Neves, Susana R; Jain, Mohit R; Li, Hong; Ma'ayan, Avi; Gordon, Ronald E; He, John Cijiang; Iyengar, RaviScience signaling2014 Feb 4ra1224497609
Differential requirement for NMDAR activity in SAP97*-mediated regulation of the number and strength of glutamatergic AMPAR-containing synapses.Liu, Mingna; Lewis, Laura D; Shi, Rebecca; Brown, Emery N; Xu, WeifengJournal of neurophysiology2014 Feb648-5824225540
Epithelial and endothelial damage induced by mechanical ventilation modes.Suki, Bela; Hubmayr, RolfCurrent opinion in critical care2014 Feb17-2424300621
Vespucci: a system for building annotated databases of nascent transcripts.Allison, Karmel A; Kaikkonen, Minna U; Gaasterland, Terry; Glass, Christopher KNucleic acids research2014 Feb2433-4724304890
Modulation of leukocyte infiltration and phenotype in microporous tissue engineering scaffolds via vector induced IL-10 expression.Gower, R Michael; Boehler, Ryan M; Azarin, Samira M; Ricci, Christine F; Leonard, Joshua N; Shea, Lonnie DBiomaterials2014 Feb2024-3124309498
Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems?Jayabalasingham, Bamini; Voss, Christiane; Ehrenman, Karen; Romano, Julia D; Smith, Maria E; Fidock, David A; Bosch, Juergen; Coppens, IsabelleAutophagy2014 Feb269-8424342964
Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids.DiMarco, Rebecca L; Su, James; Yan, Kelley S; Dewi, Ruby; Kuo, Calvin J; Heilshorn, Sarah CIntegrative biology : quantitative biosciences from nano to macro2014 Feb127-4224343706
Targeted chromatin profiling reveals novel enhancers in Ig H and Ig L chain Loci.Predeus, Alexander V; Gopalakrishnan, Suhasni; Huang, Yue; Tang, Jun; Feeney, Ann J; Oltz, Eugene M; Artyomov, Maxim NJournal of immunology (Baltimore, Md. : 1950)2014 Feb 11064-7024353267
Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis.Moore, Michael J; Zhang, Chaolin; Gantman, Emily Conn; Mele, Aldo; Darnell, Jennifer C; Darnell, Robert BNature protocols2014 Feb263-9324407355
Regenerative medicine: Of fish and men.Rando, Thomas ANature chemical biology2014 Feb91-224441638
Intention estimation in brain-machine interfaces.Fan, Joline M; Nuyujukian, Paul; Kao, Jonathan C; Chestek, Cynthia A; Ryu, Stephen I; Shenoy, Krishna VJournal of neural engineering2014 Feb1600424654266
Drosophila life span and physiology are modulated by sexual perception and reward.Gendron, Christi M; Kuo, Tsung-Han; Harvanek, Zachary M; Chung, Brian Y; Yew, Joanne Y; Dierick, Herman A; Pletcher, Scott DScience (New York, N.Y.)2014 Jan 31544-824292624
Plug-and-play fluorophores extend the spectral properties of Spinach.Song, Wenjiao; Strack, Rita L; Svensen, Nina; Jaffrey, Samie RJournal of the American Chemical Society2014 Jan 291198-20124393009
Circuit dynamics of adaptive and maladaptive behaviour.Deisseroth, KarlNature2014 Jan 16309-1724429629
Human TH9 cells are skin-tropic and have autocrine and paracrine proinflammatory capacity.Schlapbach, Christoph; Gehad, Ahmed; Yang, Chao; Watanabe, Rei; Guenova, Emmanuella; Teague, Jessica E; Campbell, Laura; Yawalkar, Nikhil; Kupper, Thomas S; Clark, Rachael AScience translational medicine2014 Jan 15219ra824431112
High-throughput platform for real-time monitoring of biological processes by multicolor single-molecule fluorescence.Chen, Jin; Dalal, Ravindra V; Petrov, Alexey N; Tsai, Albert; O'Leary, Sean E; Chapin, Karen; Cheng, Janice; Ewan, Mark; Hsiung, Pei-Lin; Lundquist, Paul; Turner, Stephen W; Hsu, David R; Puglisi, Joseph DProceedings of the National Academy of Sciences of the United States of America2014 Jan 14664-924379388
Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy.Zhao, Ziqing W; Roy, Rahul; Gebhardt, J Christof M; Suter, David M; Chapman, Alec R; Xie, X SunneyProceedings of the National Academy of Sciences of the United States of America2014 Jan 14681-624379392
Global target mRNA specification and regulation by the RNA-binding protein ZFP36.Mukherjee, Neelanjan; Jacobs, Nicholas C; Hafner, Markus; Kennington, Elizabeth A; Nusbaum, Jeffrey D; Tuschl, Thomas; Blackshear, Perry J; Ohler, UweGenome biology2014 Jan 8R1224401661
Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation.Amano, Shinya U; Cohen, Jessica L; Vangala, Pranitha; Tencerova, Michaela; Nicoloro, Sarah M; Yawe, Joseph C; Shen, Yuefei; Czech, Michael P; Aouadi, MyriamCell metabolism2014 Jan 7162-7124374218
Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.Farazi, Thalia A; Ten Hoeve, Jelle J; Brown, Miguel; Mihailovic, Aleksandra; Horlings, Hugo M; van de Vijver, Marc J; Tuschl, Thomas; Wessels, Lodewyk FaGenome biology2014 Jan 7R924398324
Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.Menon, Rajasree; Im, Hogune; Zhang, Emma Yue; Wu, Shiaw-Lin; Chen, Rui; Snyder, Michael; Hancock, William S; Omenn, Gilbert SJournal of proteome research2014 Jan 3212-2724111759
Genome-scale CRISPR-Cas9 knockout screening in human cells.Shalem, Ophir; Sanjana, Neville E; Hartenian, Ella; Shi, Xi; Scott, David A; Mikkelsen, Tarjei S; Heckl, Dirk; Ebert, Benjamin L; Root, David E; Doench, John G; Zhang, FengScience (New York, N.Y.)2014 Jan 384-724336571
Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies.Bird, Greg H; Gavathiotis, Evripidis; Labelle, James L; Katz, Samuel G; Walensky, Loren DACS chemical biology2014 Jan 3NULL24358963
Metrics for the human proteome project 2013-2014 and strategies for finding missing proteins.Lane, Lydie; Bairoch, Amos; Beavis, Ronald C; Deutsch, Eric W; Gaudet, Pascale; Lundberg, Emma; Omenn, Gilbert SJournal of proteome research2014 Jan 315-2024364385
Partial proteasome inhibitors induce hair follicle growth by stabilizing *-catenin.Yucel, Gozde; Van Arnam, John; Means, Paula Casey; Huntzicker, Erik; Altindag, Banu; Lara, Maria Fernanda; Yuan, Jenny; Kuo, Calvin; Oro, Anthony EStem cells (Dayton, Ohio)2014 Jan85-9223963711
Chromatin remodeling by the small RNA machinery in mammalian cells.Li, Long-ChengEpigenetics : official journal of the DNA Methylation Society2014 Jan 145-5224149777
Intact microRNA analysis using high resolution mass spectrometry.Kullolli, Majlinda; Knouf, Emily; Arampatzidou, Maria; Tewari, Muneesh; Pitteri, Sharon JJournal of the American Society for Mass Spectrometry2014 Jan80-724174127
Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion.Grahovac, Jelena; Wells, AlanLaboratory investigation; a journal of technical methods and pathology2014 Jan31-4024247562
Characterizing multi-omic data in systems biology.Mason, Christopher E; Porter, Sandra G; Smith, Todd MAdvances in experimental medicine and biology201415-3824292960
Identification of a unique TGF-*-dependent molecular and functional signature in microglia.Butovsky, Oleg; Jedrychowski, Mark P; Moore, Craig S; Cialic, Ron; Lanser, Amanda J; Gabriely, Galina; Koeglsperger, Thomas; Dake, Ben; Wu, Pauline M; Doykan, Camille E; Fanek, Zain; Liu, Liping; Chen, Zhuoxun; Rothstein, Jeffrey D; Ransohoff, Richard M; Nature neuroscience2014 Jan131-4324316888
A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators.Szlyk, Benjamin; Braun, Craig R; Ljubicic, Sanda; Patton, Elaura; Bird, Gregory H; Osundiji, Mayowa A; Matschinsky, Franz M; Walensky, Loren D; Danial, Nika NNature structural & molecular biology2014 Jan36-4224317490
Design and development of therapies using chimeric antigen receptor-expressing T cells.Dotti, Gianpietro; Gottschalk, Stephen; Savoldo, Barbara; Brenner, Malcolm KImmunological reviews2014 Jan107-2624329793
Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria.Strack, Rita L; Song, Wenjiao; Jaffrey, Samie RNature protocols2014 Jan146-5524356773
Demystifying the nuclear function of Argonaute proteins.Huang, Vera; Li, Long-ChengRNA biology2014 Jan18-2424384674
A brave new world: the lung microbiota in an era of change.Segal, Leopoldo N; Blaser, Martin JAnnals of the American Thoracic Society2014 JanS21-724437400
Forward and reverse mutagenesis in C. elegans.Kutscher, Lena M; Shaham, ShaiWormBook : the online review of C. elegans biology201426-Jan24449699
Chronic Spinal Cord Electrical Stimulation Protects Against 6-hydroxydopamine Lesions.Yadav, Amol P; Fuentes, Romulo; Zhang, Hao; Vinholo, Thais; Wang, Chi-Han; Freire, Marco Aurelio M; Nicolelis, Miguel A LScientific reports2014383924452435
Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions.Pagano, John M; Kwak, Hojoong; Waters, Colin T; Sprouse, Rebekka O; White, Brian S; Ozer, Abdullah; Szeto, Kylan; Shalloway, David; Craighead, Harold G; Lis, John TPLoS genetics2014 Jane100409024453987
Introduction of mismatches in a random shRNA-encoding library improves potency for phenotypic selection.Wang, Yongping; Speier, Jacqueline S; Engram-Pearl, Jessica; Wilson, Robert BPloS one2014e8739024498319
Library generation by gene shuffling.Meyer, Adam J; Ellefson, Jared W; Ellington, Andrew DCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]201415.12.1-724510437
RNA-guided genome editing of mammalian cells.Pyzocha, Neena K; Ran, F Ann; Hsu, Patrick D; Zhang, FengMethods in molecular biology (Clifton, N.J.)2014269-7724557909
Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation.Hinde, Elizabeth; Yokomori, Kyoko; Gaus, Katharina; Hahn, Klaus M; Gratton, EnricoScientific reports2014421924573109
Increasing the resolution of the adult neurogenesis picture.Lacar, Benjamin; Parylak, Sarah L; Vadodaria, Krishna C; Sarkar, Anindita; Gage, Fred HF1000prime reports2014824592320
A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling *-glucan microparticles.De Jesus, Magdia; Ostroff, Gary R; Levitz, Stuart M; Bartling, Toni R; Mantis, Nicholas JPloS one2014e9100224632738
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High-Throughput Screening for Novel Anti-Infectives Using a C. elegans Pathogenesis Model.Conery, Annie L; Larkins-Ford, Jonah; Ausubel, Frederick M; Kirienko, Natalia VCurrent protocols in chemical biology201425-3724652621
Discovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surface.Meng, Hsien-Wei; Pagano, John M; White, Brian S; Toyoda, Yoshiko; Min, Irene M; Craighead, Harold G; Shalloway, David; Lis, John T; Xiao, Kai; Jin, Moonsoo MPloS one2014e9305224675636
Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer.Matthaiou, Efthymia-Iliana; Barar, Jaleh; Sandaltzopoulos, Raphael; Li, Chunsheng; Coukos, George; Omidi, YadollahInternational journal of nanomedicine20141855-7024790428
Rare event of histone demethylation can initiate singular gene expression of olfactory receptors.Tan, Longzhi; Zong, Chenghang; Xie, X SunneyProceedings of the National Academy of Sciences of the United States of America2013 Dec 2421148-5224344257
Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.Afanador, Gustavo A; Muench, Stephen P; McPhillie, Martin; Fomovska, Alina; Schon, Arne; Zhou, Ying; Cheng, Gang; Stec, Jozef; Freundlich, Joel S; Shieh, Hong-Ming; Anderson, John W; Jacobus, David P; Fidock, David A; Kozikowski, Alan P; Fishwick, Colin WBiochemistry2013 Dec 239155-6624295325
Designing ECM-mimetic materials using protein engineering.Cai, Lei; Heilshorn, Sarah CActa biomaterialia2013 Dec 21NULL24365704
Two-photon fluorescence spectroscopy and imaging of 4-dimethylaminonaphthalimide Peptide and protein conjugates.McLean, Alan M; Socher, Elke; Varnavski, Oleg; Clark, Travis B; Imperiali, Barbara; Goodson 3rd, TheodoreThe journal of physical chemistry. B2013 Dec 1915935-4224245815
Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release.Liu, Wen; Ma, Qi; Wong, Kaki; Li, Wenbo; Ohgi, Kenny; Zhang, Jie; Aggarwal, Aneel K; Rosenfeld, Michael GCell2013 Dec 191581-9524360279
Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids.Dimarco, Rebecca L; Su, James; Yan, Kelley S; Dewi, Ruby; Kuo, Calvin J; Heilshorn, Sarah CIntegrative biology : quantitative biosciences from nano to macro2013 Dec 17NULL24343706
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling.Lim, Xinhong; Tan, Si Hui; Koh, Winston Lian Chye; Chau, Rosanna Man Wah; Yan, Kelley S; Kuo, Calvin J; van Amerongen, Renee; Klein, Allon Moshe; Nusse, RoelScience (New York, N.Y.)2013 Dec 61226-3024311688
Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period.Whiteus, Christina; Freitas, Catarina; Grutzendler, JaimeNature2013 Dec 4NULL24305053
Dynamic Recognition of the mRNA Cap by Saccharomyces cerevisiae eIF4E.O'Leary, Sean E; Petrov, Alexey; Chen, Jin; Puglisi, Joseph DStructure (London, England : 1993)2013 Dec 32197-20724183571
RNA-sequencing from single nuclei.Grindberg, Rashel V; Yee-Greenbaum, Joyclyn L; McConnell, Michael J; Novotny, Mark; O'Shaughnessy, Andy L; Lambert, Georgina M; Arauzo-Bravo, Marcos J; Lee, Jun; Fishman, Max; Robbins, Gillian E; Lin, Xiaoying; Venepally, Pratap; Badger, Jonathan H; GalbrProceedings of the National Academy of Sciences of the United States of America2013 Dec 319802-724248345
Engineering Three-Dimensional Stem Cell Morphogenesis for the Development of Tissue Models and Scalable Regenerative Therapeutics.Kinney, Melissa A; Hookway, Tracy A; Wang, Yun; McDevitt, Todd CAnnals of biomedical engineering2013 Dec 3NULL24297495
Pleomorphic ensembles: formation of large clusters composed of weakly interacting multivalent molecules.Falkenberg, Cibele V; Blinov, Michael L; Loew, Leslie MBiophysical journal2013 Dec 32451-6024314076
In vivo robotics: the automation of neuroscience and other intact-system biological fields.Kodandaramaiah, Suhasa B; Boyden, Edward S; Forest, Craig RAnnals of the New York Academy of Sciences2013 Dec63-7123841584
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Single Cell Analysis of HCV-Infected Patient Hepatocytes: The Science Is No Longer Science Fiction.Sheahan, Timothy P; Rice, Charles MGastroenterology2013 Dec1199-20224176873
Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics.McCall, Jordan G; Kim, Tae-il; Shin, Gunchul; Huang, Xian; Jung, Yei Hwan; Al-Hasani, Ream; Omenetto, Fiorenzo G; Bruchas, Michael R; Rogers, John ANature protocols2013 Dec2413-2824202555
Glia and pain: Is chronic pain a gliopathy?Ji, Ru-Rong; Berta, Temugin; Nedergaard, MaikenPain2013 DecNULL24347804
Development of neurons and glia.Pfaff, Samuel; Shaham, ShaiCurrent opinion in neurobiology2013 Dec901-224358527
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Activated ClpP kills persisters and eradicates a chronic biofilm infection.Conlon, B P; Nakayasu, E S; Fleck, L E; LaFleur, M D; Isabella, V M; Coleman, K; Leonard, S N; Smith, R D; Adkins, J N; Lewis, KNature2013 Nov 21365-7024226776
The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation.Parl, Angelika; Mitchell, Sabrina L; Clay, Hayley B; Reiss, Sara; Li, Zhen; Murdock, Deborah GBiochemical and biophysical research communications2013 Nov 15418-2424161390
Co-regulation of primary mouse hepatocyte viability and function by oxygen and matrix.Buck, Lorenna D; Inman, S Walker; Rusyn, Ivan; Griffith, Linda GBiotechnology and bioengineering2013 Nov 13NULL24222008
The role of transposable elements in health and diseases of the central nervous system.Reilly, Matthew T; Faulkner, Geoffrey J; Dubnau, Joshua; Ponomarev, Igor; Gage, Fred HThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Nov 617577-8624198348
Candida krusei colonization in patients with gastrointestinal diseases.Huong, Duong Thu; Zhao, Yanan; Nguyet, Nguyen Thi; Loan, Ta Thi; Binh, Nguyen Thi Thanh; Thinh, Nguyen Van; Hanh, Nguyen Thi Hong; Perez-Perez, Guillermo I; Perlin, David SMedical mycology2013 Nov884-723815437
Pathology imaging informatics for quantitative analysis of whole-slide images.Kothari, Sonal; Phan, John H; Stokes, Todd H; Wang, May DJournal of the American Medical Informatics Association : JAMIA2013 Nov-Dec1099-10823959844
Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers.Ricarte-Filho, Julio C; Li, Sheng; Garcia-Rendueles, Maria E R; Montero-Conde, Cristina; Voza, Francesca; Knauf, Jeffrey A; Heguy, Adriana; Viale, Agnes; Bogdanova, Tetyana; Thomas, Geraldine A; Mason, Christopher E; Fagin, James AThe Journal of clinical investigation2013 Nov 14935-4424135138
Genome engineering using the CRISPR-Cas9 system.Ran, F Ann; Hsu, Patrick D; Wright, Jason; Agarwala, Vineeta; Scott, David A; Zhang, FengNature protocols2013 Nov2281-30824157548
Mosaic copy number variation in human neurons.McConnell, Michael J; Lindberg, Michael R; Brennand, Kristen J; Piper, Julia C; Voet, Thierry; Cowing-Zitron, Chris; Shumilina, Svetlana; Lasken, Roger S; Vermeesch, Joris R; Hall, Ira M; Gage, Fred HScience (New York, N.Y.)2013 Nov 1632-724179226
Emphysema and mechanical stress-induced lung remodeling.Suki, Bela; Sato, Susumu; Parameswaran, Harikrishnan; Szabari, Margit V; Takahashi, Ayuko; Bartolak-Suki, ErzsebetPhysiology (Bethesda, Md.)2013 Nov404-1324186935
Role of childhood infection in the sequelae of H. pylori disease.Harris, Paul R; Smythies, Lesley E; Smith, Phillip D; Perez-Perez, Guillermo IGut microbes2013 Nov-Dec426-3824275060
Portrayals of Reproductive and Sexual Health on Prime-Time Television.Pariera, Katrina L; Hether, Heather J; Murphy, Sheila T; de Castro Buffington, Sandra; Baezconde-Garbanati, LourdesHealth communication2013 Oct 24NULL24156468
The strategy, organization, and progress of the HUPO Human Proteome Project.Omenn, Gilbert SJournal of proteomics2013 Oct 19NULL24145142
Fiber optical parametric oscillator for coherent anti-Stokes Raman scattering microscopy.Lamb, Erin S; Lefrancois, Simon; Ji, Minbiao; Wadsworth, William J; Sunney Xie, X; Wise, Frank WOptics letters2013 Oct 154154-724321947
Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.Doksani, Ylli; Wu, John Y; de Lange, Titia; Zhuang, XiaoweiCell2013 Oct 10345-5624120135
Molecular engineering of glycosaminoglycan chemistry for biomolecule delivery.Miller, Tobias; Goude, Melissa C; McDevitt, Todd C; Temenoff, Johnna SActa biomaterialia2013 Oct 9NULL24121191
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation.Chanda, Soham; Marro, Samuele; Wernig, Marius; Sudhof, Thomas CProceedings of the National Academy of Sciences of the United States of America2013 Oct 816622-724046374
Pseudomonas aeruginosa Biofilms in Disease.Mulcahy, Lawrence R; Isabella, Vincent M; Lewis, KimMicrobial ecology2013 Oct 6NULL24096885
Simple paper-based test for measuring blood hemoglobin concentration in resource-limited settings.Yang, Xiaoxi; Piety, Nathaniel Z; Vignes, Seth M; Benton, Melody S; Kanter, Julie; Shevkoplyas, Sergey SClinical chemistry2013 Oct1506-1323788584
Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons.Zhang, Zhi-Jun; Cao, De-Li; Zhang, Xin; Ji, Ru-Rong; Gao, Yong-JingPain2013 Oct2185-9723831863
Targeted induction of endogenous NKX3-1 by small activating RNA inhibits prostate tumor growth.Ren, Shancheng; Kang, Moo Rim; Wang, Ji; Huang, Vera; Place, Robert F; Sun, Yinhao; Li, Long-ChengThe Prostate2013 Oct1591-60123836514
CRISPR RNA-guided activation of endogenous human genes.Maeder, Morgan L; Linder, Samantha J; Cascio, Vincent M; Fu, Yanfang; Ho, Quan H; Joung, J KeithNature methods2013 Oct977-923892898
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.Kim, Woojin; Bird, Gregory H; Neff, Tobias; Guo, Guoji; Kerenyi, Marc A; Walensky, Loren D; Orkin, Stuart HNature chemical biology2013 Oct643-5023974116
Novelties in pharmacological management of cardiopulmonary resuscitation.Bartos, Jason A; Yannopoulos, DemetrisCurrent opinion in critical care2013 Oct417-2323995130
Absolute quantification by droplet digital PCR versus analog real-time PCR.Hindson, Christopher M; Chevillet, John R; Briggs, Hilary A; Gallichotte, Emily N; Ruf, Ingrid K; Hindson, Benjamin J; Vessella, Robert L; Tewari, MuneeshNature methods2013 Oct1003-523995387
The ins and outs of hepatitis C virus entry and assembly.Lindenbach, Brett D; Rice, Charles MNature reviews. Microbiology2013 Oct688-70024018384
A brain-machine interface for control of medically-induced coma.Shanechi, Maryam M; Chemali, Jessica J; Liberman, Max; Solt, Ken; Brown, Emery NPLoS computational biology2013 Octe100328424204231
Spontaneous cardiomyocyte differentiation of mouse embryoid bodies regulated by hydrogel crosslink density.Chung, Cindy; Pruitt, Beth L; Heilshorn, Sarah CBiomaterials science2013 Oct 11082-109024748962
Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer.Wu, Manhong; Xu, Yue; Fitch, William L; Zheng, Ming; Merritt, Robert E; Shrager, Joseph B; Zhang, Weiruo; Dill, David L; Peltz, Gary; Hoang, Chuong DRapid communications in mass spectrometry : RCM2013 Sep 302091-823943330
ERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertion.Song, Roy S; Massenburg, Ben; Wenderski, Wendy; Jayaraman, Vino; Thompson, Lauren; Neves, Susana RProceedings of the National Academy of Sciences of the United States of America2013 Sep 1715437-4223986500
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.Ran, F Ann; Hsu, Patrick D; Lin, Chie-Yu; Gootenberg, Jonathan S; Konermann, Silvana; Trevino, Alexandro E; Scott, David A; Inoue, Azusa; Matoba, Shogo; Zhang, Yi; Zhang, FengCell2013 Sep 121380-923992846
Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.Sha, Fern; Gencer, Emel Basak; Georgeon, Sandrine; Koide, Akiko; Yasui, Norihisa; Koide, Shohei; Hantschel, OliverProceedings of the National Academy of Sciences of the United States of America2013 Sep 1014924-923980151
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data.Rapaport, Franck; Khanin, Raya; Liang, Yupu; Pirun, Mono; Krek, Azra; Zumbo, Paul; Mason, Christopher E; Socci, Nicholas D; Betel, DoronGenome biology2013 Sep 10R9524020486
Erratum: Thermal analysis of injectable, cellular-scale optoelectronics with pulsed power.Li, Yuhang; Shi, Xiaoting; Song, Jizhou; Lu, Chaofeng; Kim, Tae-Il; McCall, Jordan G; Bruchas, Michael R; Rogers, John A; Huang, YonggangProceedings. Mathematical, physical, and engineering sciences / the Royal Society2013 Sep 82013039824062627
Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy.Ji, Minbiao; Orringer, Daniel A; Freudiger, Christian W; Ramkissoon, Shakti; Liu, Xiaohui; Lau, Darryl; Golby, Alexandra J; Norton, Isaiah; Hayashi, Marika; Agar, Nathalie Y R; Young, Geoffrey S; Spino, Cathie; Santagata, Sandro; Camelo-Piragua, Sandra; LScience translational medicine2013 Sep 4201ra11924005159
A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia.Lu, Yan; Dong, Hailong; Gao, Yandong; Gong, Yuanyuan; Ren, Yingna; Gu, Nan; Zhou, Shudi; Xia, Nan; Sun, Yan-Yan; Ji, Ru-Rong; Xiong, LizeThe Journal of clinical investigation2013 Sep 34050-6223979158
Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology.Omenn, Gilbert S; Menon, Rajasree; Zhang, YangJournal of proteomics2013 Sep 228-3723603631
Association between Helicobacter pylori and mortality in the NHANES III study.Chen, Yu; Segers, Stephanie; Blaser, Martin JGut2013 Sep1262-923303440
The matrikine tenascin-C protects multipotential stromal cells/mesenchymal stem cells from death cytokines such as FasL.Rodrigues, Melanie; Yates, Cecelia C; Nuschke, Austin; Griffith, Linda; Wells, AlanTissue engineering. Part A2013 Sep1972-8323541003
HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses.Contreras-Galindo, Rafael; Kaplan, Mark H; He, Shirley; Contreras-Galindo, Angie C; Gonzalez-Hernandez, Marta J; Kappes, Ferdinand; Dube, Derek; Chan, Susana M; Robinson, Dan; Meng, Fan; Dai, Manhong; Gitlin, Scott D; Chinnaiyan, Arul M; Omenn, Gilbert S;Genome research2013 Sep1505-1323657884
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells.Tang, Xin; Zhou, Li; Wagner, Alecia M; Marchetto, Maria C N; Muotri, Alysson R; Gage, Fred H; Chen, GongStem cell research2013 Sep743-5723759711
DNA targeting specificity of RNA-guided Cas9 nucleases.Hsu, Patrick D; Scott, David A; Weinstein, Joshua A; Ran, F Ann; Konermann, Silvana; Agarwala, Vineeta; Li, Yinqing; Fine, Eli J; Wu, Xuebing; Shalem, Ophir; Cradick, Thomas J; Marraffini, Luciano A; Bao, Gang; Zhang, FengNature biotechnology2013 Sep827-3223873081
Local cortical dynamics of burst suppression in the anaesthetized brain.Lewis, Laura D; Ching, Shinung; Weiner, Veronica S; Peterfreund, Robert A; Eskandar, Emad N; Cash, Sydney S; Brown, Emery N; Purdon, Patrick LBrain : a journal of neurology2013 Sep2727-3723887187
Recombinant expression of backbone-cyclized polypeptides.Borra, Radhika; Camarero, Julio ABiopolymers2013 Sep502-923893781
Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.Jourdan, Tony; Godlewski, Grzegorz; Cinar, Resat; Bertola, Adeline; Szanda, Gergýý; Liu, Jie; Tam, Joseph; Han, Tiffany; Mukhopadhyay, Bani; Skarulis, Monica C; Ju, Cynthia; Aouadi, Myriam; Czech, Michael P; Kunos, GeorgeNature medicine2013 Sep1132-4023955712
Therapeutic strategies impacting cancer cell glutamine metabolism.Lukey, Michael J; Wilson, Kristin F; Cerione, Richard AFuture medicinal chemistry2013 Sep1685-70024047273
Neural tube defects, folate, and immune modulation.Denny, Kerina J; Jeanes, Angela; Fathe, Kristin; Finnell, Richard H; Taylor, Stephen M; Woodruff, Trent MBirth defects research. Part A, Clinical and molecular teratology2013 Sep602-924078477
lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.Yang, Liuqing; Lin, Chunru; Jin, Chunyu; Yang, Joy C; Tanasa, Bogdan; Li, Wenbo; Merkurjev, Daria; Ohgi, Kenneth A; Meng, Da; Zhang, Jie; Evans, Christopher P; Rosenfeld, Michael GNature2013 Aug 29598-60223945587
Optical control of mammalian endogenous transcription and epigenetic states.Konermann, Silvana; Brigham, Mark D; Trevino, Alexandro E; Hsu, Patrick D; Heidenreich, Matthias; Cong, Le; Platt, Randall J; Scott, David A; Church, George M; Zhang, FengNature2013 Aug 22472-623877069
Unifying model for molecular determinants of the preselection Výý repertoire.Gopalakrishnan, Suhasni; Majumder, Kinjal; Predeus, Alexander; Huang, Yue; Koues, Olivia I; Verma-Gaur, Jiyoti; Loguercio, Salvatore; Su, Andrew I; Feeney, Ann J; Artyomov, Maxim N; Oltz, Eugene MProceedings of the National Academy of Sciences of the United States of America2013 Aug 20E3206-1523918392
Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing Rejection of Differentiated Human Embryonic Stem Cells Following Transplantation.Huber, Bruno C; Ransohoff, Julia D; Ransohoff, Katherine J; Riegler, Johannes; Ebert, Antje; Kodo, Kazuki; Gong, Yongquan; Sanchez-Freire, Veronica; Dey, Devaveena; Kooreman, Nigel G; Diecke, Sebastian; Zhang, Wendy Y; Odegaard, Justin; Hu, Shijun; Gold, Stem cells (Dayton, Ohio)2013 Aug 16NULL24038578
FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.Webb, Ashley E; Pollina, Elizabeth A; Vierbuchen, Thomas; Urban, Noelia; Ucar, Duygu; Leeman, Dena S; Martynoga, Ben; Sewak, Madhavi; Rando, Thomas A; Guillemot, Francois; Wernig, Marius; Brunet, AnneCell reports2013 Aug 15477-9123891001
Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels.Pagadala, Promila; Park, Chul-Kyu; Bang, Sangsu; Xu, Zheng-Zhong; Xie, Rou-Gang; Liu, Tong; Han, Bao-Xia; Tracey Jr, W Daniel; Wang, Fan; Ji, Ru-RongThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Aug 1413425-3023946399
Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription.Kaikkonen, Minna U; Spann, Nathanael J; Heinz, Sven; Romanoski, Casey E; Allison, Karmel A; Stender, Joshua D; Chun, Hyun B; Tough, David F; Prinjha, Rab K; Benner, Christopher; Glass, Christopher KMolecular cell2013 Aug 8310-2523932714
In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide.Ji, Yanbin; Majumder, Subhabrata; Millard, Melissa; Borra, Radhika; Bi, Tao; Elnagar, Ahmed Y; Neamati, Nouri; Shekhtman, Alexander; Camarero, Julio AJournal of the American Chemical Society2013 Aug 711623-3323848581
Identification of small molecules for human hepatocyte expansion and iPS differentiation.Shan, Jing; Schwartz, Robert E; Ross, Nathan T; Logan, David J; Thomas, David; Duncan, Stephen A; North, Trista E; Goessling, Wolfram; Carpenter, Anne E; Bhatia, Sangeeta NNature chemical biology2013 Aug514-2023728495
Density-dependent cooperative non-specific binding in solid-phase SELEX affinity selection.Ozer, Abdullah; White, Brian S; Lis, John T; Shalloway, DavidNucleic acids research2013 Aug7167-7523737446
The aging brain and anesthesia.Brown, Emery N; Purdon, Patrick LCurrent opinion in anaesthesiology2013 Aug414-923820102
Autonomous molecular cascades for evaluation of cell surfaces.Rudchenko, Maria; Taylor, Steven; Pallavi, Payal; Dechkovskaia, Alesia; Khan, Safana; Butler Jr, Vincent P; Rudchenko, Sergei; Stojanovic, Milan NNature nanotechnology2013 Aug580-623892986
Multimodal Interaction with BCL-2 Family Proteins Underlies the Proapoptotic Activity of PUMA BH3.Edwards, Amanda L; Gavathiotis, Evripidis; Labelle, James L; Braun, Craig R; Opoku-Nsiah, Kwadwo A; Bird, Gregory H; Walensky, Loren DChemistry & biology2013 Jul 25888-90223890007
Deciphering and reversing tumor immune suppression.Motz, Greg T; Coukos, GeorgeImmunity2013 Jul 2561-7323890064
The complex relationship between the light-entrainable and methamphetamine-sensitive circadian oscillators: evidence from behavioral studies of Period-mutant mice.Pendergast, Julie S; Niswender, Kevin D; Yamazaki, ShinThe European journal of neuroscience2013 Jul 22NULL23869717
Imaging bacterial protein expression using genetically encoded RNA sensors.Song, Wenjiao; Strack, Rita L; Jaffrey, Samie RNature methods2013 Jul 21NULL23872791
Enzyme-directed assembly of a nanoparticle probe in tumor tissue.Chien, Miao-Ping; Thompson, Matthew P; Barback, Christopher V; Ku, Ti-Hsuan; Hall, David J; Gianneschi, Nathan CAdvanced materials (Deerfield Beach, Fla.)2013 Jul 123599-60423712821
In vivo robotics: the automation of neuroscience and other intact-system biological fields.Kodandaramaiah, Suhasa B; Boyden, Edward S; Forest, Craig RAnnals of the New York Academy of Sciences2013 Jul 10NULL23841584
Pharmacokinetics and tissue distribution of humanin and its analogues in male rodents.Chin, Yung-Ping; Keni, Jyotsna; Wan, Junxiang; Mehta, Hemal; Anene, Francine; Jia, Yue; Lue, Yan-He; Swerdloff, Ronald; Cobb, Laura J; Wang, Christina; Cohen, PinchasEndocrinology2013 Jul 8NULL23836030
Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice.Billerbeck, Eva; Horwitz, Joshua A; Labitt, Rachael N; Donovan, Bridget M; Vega, Kevin; Budell, William C; Koo, Gloria C; Rice, Charles M; Ploss, AlexanderJournal of immunology (Baltimore, Md. : 1950)2013 Jul 5NULL23833235
Thalamocortical mechanisms for the anteriorization of alpha rhythms during propofol-induced unconsciousness.Vijayan, Sujith; Ching, Shinung; Purdon, Patrick L; Brown, Emery N; Kopell, Nancy JThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Jul 311070-523825412
Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.Street, Sarah E; Kramer, Nicholas J; Walsh, Paul L; Taylor-Blake, Bonnie; Yadav, Manisha C; King, Ian F; Vihko, Pirkko; Wightman, R Mark; Millan, Jose Luis; Zylka, Mark JThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Jul 311314-2223825434
Tumor-specific T cells in human merkel cell carcinomas: a possible role for tregs and T-cell exhaustion in reducing T-cell responses.Dowlatshahi, Mitra; Huang, Victor; Gehad, Ahmed E; Jiang, Ying; Calarese, Adam; Teague, Jessica E; Dorosario, Andrew A; Cheng, Jingwei; Nghiem, Paul; Schanbacher, Carl F; Thakuria, Manisha; Schmults, Chrysalyne D; Wang, Linda C; Clark, Rachael AThe Journal of investigative dermatology2013 Jul1879-8923419694
TCF7L2 variation and proliferative diabetic retinopathy.Luo, Jing; Zhao, Ling; Chen, Aaron Yun; Zhang, Xiaohui; Zhu, Jin; Zhao, Jiagang; Ouyang, Hong; Luo, Hongrong; Song, Yaojun; Lee, Janet; Patel, Sherrina H; Shaw, Peter X; Sadda, Srinivas; Zhuo, Yehong; Rosenfeld, Michael G; Zhang, KangDiabetes2013 Jul2613-723434931
The effect of desulfation of chondroitin sulfate on interactions with positively charged growth factors and upregulation of cartilaginous markers in encapsulated MSCs.Lim, Jeremy J; Temenoff, Johnna SBiomaterials2013 Jul5007-1823570717
Development of a multiplex phenotypic cell-based high throughput screening assay to identify novel hepatitis C virus antivirals.Kim, Hee-Young; Li, Xiaolan; Jones, Christopher T; Rice, Charles M; Garcia, Jean-Michel; Genovesio, Auguste; Hansen, Michael A E; Windisch, Marc PAntiviral research2013 Jul11-Jun23660623
Association of caesarean delivery with child adiposity from age 6 weeks to 15 years.Blustein, J; Attina, T; Liu, M; Ryan, A M; Cox, L M; Blaser, M J; Trasande, LInternational journal of obesity (2005)2013 Jul900-623670220
Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola.Shedlock, Devon J; Aviles, Jenna; Talbott, Kendra T; Wong, Gary; Wu, Stephan J; Villarreal, Daniel O; Myles, Devin Jf; Croyle, Maria A; Yan, Jian; Kobinger, Gary P; Weiner, David BMolecular therapy : the journal of the American Society of Gene Therapy2013 Jul1432-4423670573
The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis.Jia, Y; Lue, Y-H; Swerdloff, R; Lee, K-W; Cobb, L J; Cohen, P; Wang, CAndrology2013 Jul651-923686888
MicroRNA target site identification by integrating sequence and binding information.Majoros, William H; Lekprasert, Parawee; Mukherjee, Neelanjan; Skalsky, Rebecca L; Corcoran, David L; Cullen, Bryan R; Ohler, UweNature methods2013 Jul630-323708386
Common variant in VEGFA and response to anti-VEGF therapy for neovascular age-related macular degeneration.Zhao, L; Grob, S; Avery, R; Kimura, A; Pieramici, D; Lee, J; Rabena, M; Ortiz, S; Quach, J; Cao, G; Luo, H; Zhang, M; Pei, M; Song, Y; Tornambe, P; Goldbaum, M; Ferreyra, H; Kozak, I; Zhang, KCurrent molecular medicine2013 Jul929-3423745581
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.Scheel, Troels K H; Rice, Charles MNature medicine2013 Jul837-4923836234
Statistical analysis of molecular signal recording.Glaser, Joshua I; Zamft, Bradley M; Marblestone, Adam H; Moffitt, Jeffrey R; Tyo, Keith; Boyden, Edward S; Church, George; Kording, Konrad PPLoS computational biology2013 Jule100314523874187
Ethnicity is a strong predictor for Helicobacter pylori infection in young women in a multi-ethnic European city.den Hollander, W J; Holster, I L; den Hoed, C M; van Deurzen, F; van Vuuren, A J; Jaddoe, V W; Hofman, A; Perez, G I Perez; Blaser, M J; Moll, H A; Kuipers, E JJournal of gastroenterology and hepatology2013 Jun 28NULL23808840
Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes.Tabler, Jacqueline M; Barrell, William B; Szabo-Rogers, Heather L; Healy, Christopher; Yeung, Yvonne; Perdiguero, Elisa Gomez; Schulz, Christian; Yannakoudakis, Basil Z; Mesbahi, Aida; Wlodarczyk, Bogdan; Geissmann, Frederic; Finnell, Richard H; WallingfoDevelopmental cell2013 Jun 24623-3523806618
The Dormancy Dilemma: Quiescence versus Balanced Proliferation.Wells, Alan; Griffith, Linda; Wells, Jakob Z; Taylor, Donald PCancer research2013 Jun 2123794703
Knowledge-Based Design of a Biosensor to Quantify Localized ERK Activation in Living Cells.Kummer, Lutz; Hsu, Chia-Wen; Dagliyan, Onur; Macnevin, Christopher; Kaufholz, Melanie; Zimmermann, Bastian; Dokholyan, Nikolay V; Hahn, Klaus M; Pluckthun, AndreasChemistry & biology2013 Jun 20847-5623790495
Glia and pain: Is chronic pain a gliopathy?Ji, Ru-Rong; Berta, Temugin; Nedergaard, MaikenPain2013 Jun 20NULL23792284
TH2 Cytokines from Malignant Cells Suppress TH1 Responses and Enforce a Global TH2 Bias in Leukemic Cutaneous T-cell Lymphoma.Guenova, Emmanuella; Watanabe, Rei; Teague, Jessica E; Desimone, Jennifer A; Jiang, Ying; Dowlatshahi, Mitra; Schlapbach, Christoph; Schaekel, Knut; Rook, Alain H; Tawa, Marianne; Fisher, David C; Kupper, Thomas S; Clark, Rachael AClinical cancer research : an official journal of the American Association for Cancer Research2013 Jun 1923785046
Recombinant probes for visualizing endogenous synaptic proteins in living neurons.Gross, Garrett G; Junge, Jason A; Mora, Rudy J; Kwon, Hyung-Bae; Olson, C Anders; Takahashi, Terry T; Liman, Emily R; Ellis-Davies, Graham C R; McGee, Aaron W; Sabatini, Bernardo L; Roberts, Richard W; Arnold, Don BNeuron2013 Jun 19971-8523791193
Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury.Thomas, Aline M; Shea, Lonnie DJournal of controlled release : official journal of the Controlled Release Society2013 Jun 18421-42923791981
Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts.Davila, Jonathan; Chanda, Soham; Ang, Cheen Euong; Sudhof, Thomas C; Wernig, MariusJournal of neuroscience methods2013 Jun 15104-923562599
Semiconductor quantum dots for bioimaging and biodiagnostic applications.Kairdolf, Brad A; Smith, Andrew M; Stokes, Todd H; Wang, May D; Young, Andrew N; Nie, ShumingAnnual review of analytical chemistry (Palo Alto, Calif.)2013 Jun 12143-6223527547
XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Nagarajan, Vinay K; Jones, Christopher I; Newbury, Sarah F; Green, Pamela JBiochimica et biophysica acta2013 Jun-Jul590-60323517755
New approaches for sensing metabolites and proteins in live cells using RNA.Strack, Rita L; Jaffrey, Samie RCurrent opinion in chemical biology2013 Jun 6NULL23746618
Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations.Guenthner, Casey J; Miyamichi, Kazunari; Yang, Helen H; Heller, H Craig; Luo, LiqunNeuron2013 Jun 5773-8423764283
Rapid single-step induction of functional neurons from human pluripotent stem cells.Zhang, Yingsha; Pak, Changhui; Han, Yan; Ahlenius, Henrik; Zhang, Zhenjie; Chanda, Soham; Marro, Samuele; Patzke, Christopher; Acuna, Claudio; Covy, Jason; Xu, Wei; Yang, Nan; Danko, Tamas; Chen, Lu; Wernig, Marius; Sudhof, Thomas CNeuron2013 Jun 5785-9823764284
Pathways in microbe-induced obesity.Cox, Laura M; Blaser, Martin JCell metabolism2013 Jun 4883-9423747247
Density-dependent cooperative non-specific binding in solid-phase SELEX affinity selection.Ozer, Abdullah; White, Brian S; Lis, John T; Shalloway, DavidNucleic acids research2013 Jun 3NULL23737446
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation.Li, Wenbo; Notani, Dimple; Ma, Qi; Tanasa, Bogdan; Nunez, Esperanza; Chen, Aaron Yun; Merkurjev, Daria; Zhang, Jie; Ohgi, Kenneth; Song, Xiaoyuan; Oh, Soohwan; Kim, Hong-Sook; Glass, Christopher K; Rosenfeld, Michael GNature2013 Jun 223728302
Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-ýý1 in the CNS.Koeglsperger, Thomas; Li, Shaomin; Brenneis, Christian; Saulnier, Jessica L; Mayo, Lior; Carrier, Yijun; Selkoe, Dennis J; Weiner, Howard LGlia2013 Jun985-100223536313
Design and validation of a real-time spiking-neural-network decoder for brain-machine interfaces.Dethier, Julie; Nuyujukian, Paul; Ryu, Stephen I; Shenoy, Krishna V; Boahen, KwabenaJournal of neural engineering2013 Jun03600823574919
Design and validation of a real-time spiking-neural-network decoder for brain-machine interfaces.Dethier, Julie; Nuyujukian, Paul; Ryu, Stephen I; Shenoy, Krishna V; Boahen, KwabenaJournal of neural engineering2013 Jun3600823574919
Coordinated conformational and compositional dynamics drive ribosome translocation.Chen, Jin; Petrov, Alexey; Tsai, Albert; O'Leary, Sean E; Puglisi, Joseph DNature structural & molecular biology2013 Jun718-2723624862
Angiophagy: mechanism of microvascular recanalization independent of the fibrinolytic system.Grutzendler, JaimeStroke; a journal of cerebral circulation2013 JunS84-623709741
Tumor suppressors: enhancers or suppressors of regeneration?Pomerantz, Jason H; Blau, Helen MDevelopment (Cambridge, England)2013 Jun2502-1223715544
Collaborative Chronic Care Networks (C3Ns) to transform chronic illness care.Margolis, Peter A; Peterson, Laura E; Seid, MichaelPediatrics2013 JunS219-2323729764
Cancer Stem Cells: A Moving Target.Francipane, Maria Giovanna; Chandler, Julie; Lagasse, EricCurrent pathobiology reports2013 Jun 1111-11823914341
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.Rajala, Hanna L M; Eldfors, Samuli; Kuusanmaki, Heikki; van Adrichem, Arjan J; Olson, Thomas; Lagstrom, Sonja; Andersson, Emma I; Jerez, Andres; Clemente, Michael J; Yan, Yiyi; Zhang, Dan; Awwad, Andy; Ellonen, Pekka; Kallioniemi, Olli; Wennerberg, KristeBlood2013 May 304541-5023596048
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.Miller, Miles A; Meyer, Aaron S; Beste, Michael T; Lasisi, Zainab; Reddy, Sonika; Jeng, Karen W; Chen, Chia-Hung; Han, Jongyoon; Isaacson, Keith; Griffith, Linda G; Lauffenburger, Douglas AProceedings of the National Academy of Sciences of the United States of America2013 May 28E2074-8323674691
Enzyme-Directed Assembly of a Nanoparticle Probe in Tumor Tissue.Chien, Miao-Ping; Thompson, Matthew P; Barback, Christopher V; Ku, Ti-Hsuan; Hall, David J; Gianneschi, Nathan CAdvanced materials (Deerfield Beach, Fla.)2013 May 2823712821
Real-time detection of isothermal amplification reactions with thermostable catalytic hairpin assembly.Jiang, Yu Sherry; Li, Bingling; Milligan, John N; Bhadra, Sanchita; Ellington, Andrew DJournal of the American Chemical Society2013 May 227430-323647466
Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1ýý and ERK signaling in the spinal cord of mice.Berta, T; Liu, Y-C; Xu, Z-Z; Ji, R-RNeuroscience2013 May 2123707980
Potentiation of Azole Antifungals by 2-adamantanamine.Lafleur, Michael D; Sun, Lingmei; Lister, Ida; Keating, John; Nantel, Andre; Long, Lisa; Ghannoum, Mahmoud; North, Jeffrey; Lee, Richard E; Coleman, Ken; Dahl, Thomas; Lewis, KimAntimicrobial agents and chemotherapy2013 May 20NULL23689724
RNA Protein Interaction in Neurons.Darnell, Robert BAnnual review of neuroscience2013 May 2023701460
Neuroprotectin/Protectin D1 protects neuropathic pain in mice after nerve trauma.Xu, Zhen-Zhong; Liu, Xing-Jun; Berta, Temugin; Park, Chul-Kyu; Lu, Ning; Serhan, Charles N; Ji, Ru-RongAnnals of neurology2013 May 1823686636
Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice.Aouadi, Myriam; Tencerova, Michaela; Vangala, Pranitha; Yawe, Joseph C; Nicoloro, Sarah M; Amano, Shinya U; Cohen, Jessica L; Czech, Michael PProceedings of the National Academy of Sciences of the United States of America2013 May 148278-8323630254
HIV Infection Reveals Wide-Spread Expansion of Novel Centromeric Human Endogenous Retroviruses.Contreras-Galindo, Rafael; Kaplan, Mark H; He, Shirley; Contreras-Galindo, Angie C; Gonzalez-Hernandez, Marta J; Kappes, Ferdinand; Dube, Derek; Chan, Susana M; Robinson, Dan; Meng, Fan; Dai, Manhong; Gitlin, Scott D; Chinnaiyan, Arul M; Omenn, Gilbert S;Genome research2013 May 823657884
Geometric control of vascular networks to enhance engineered tissue integration and function.Baranski, Jan D; Chaturvedi, Ritika R; Stevens, Kelly R; Eyckmans, Jeroen; Carvalho, Brian; Solorzano, Ricardo D; Yang, Michael T; Miller, Jordan S; Bhatia, Sangeeta N; Chen, Christopher SProceedings of the National Academy of Sciences of the United States of America2013 May 77586-9123610423
Humanin: a harbinger of mitochondrial-derived peptides?Lee, Changhan; Yen, Kelvin; Cohen, PinchasTrends in endocrinology and metabolism: TEM2013 May222-823402768
Insulin signalling mechanisms for triacylglycerol storage.Czech, M P; Tencerova, M; Pedersen, D J; Aouadi, MDiabetologia2013 May949-6423443243
CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance.Guo, Chang-An; Kogan, Sophia; Amano, Shinya U; Wang, Mengxi; Dagdeviren, Sezin; Friedline, Randall H; Aouadi, Myriam; Kim, Jason K; Czech, Michael PAmerican journal of physiology. Endocrinology and metabolism2013 May 1E951-6323482447
Single-molecule imaging of transcription factor binding to DNA in live mammalian cells.Gebhardt, J Christof M; Suter, David M; Roy, Rahul; Zhao, Ziqing W; Chapman, Alec R; Basu, Srinjan; Maniatis, Tom; Xie, X SunneyNature methods2013 May421-623524394
Activation of transposable elements during aging and neuronal decline in Drosophila.Li, Wanhe; Prazak, Lisa; Chatterjee, Nabanita; Gruninger, Servan; Krug, Lisa; Theodorou, Delphine; Dubnau, JoshNature neuroscience2013 May529-3123563579
Targeting tumor cell motility as a strategy against invasion and metastasis.Wells, Alan; Grahovac, Jelena; Wheeler, Sarah; Ma, Bo; Lauffenburger, DouglasTrends in pharmacological sciences2013 May283-923571046
Generation of oligodendroglial cells by direct lineage conversion.Yang, Nan; Zuchero, J Bradley; Ahlenius, Henrik; Marro, Samuele; Ng, Yi Han; Vierbuchen, Thomas; Hawkins, John S; Geissler, Richard; Barres, Ben A; Wernig, MariusNature biotechnology2013 May434-923584610
Playing fullBAK.Walensky, Loren DCell cycle (Georgetown, Tex.)2013 May 11333-423588072
Can 'humanized' mice improve drug development in the 21st century?Peltz, GaryTrends in pharmacological sciences2013 May255-6023602782
New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?Liu, Tong; Ji, Ru-RongPflugers Archiv : European journal of physiology2013 May 123636773
Direct BAKtivation.Walensky, Loren DNature structural & molecular biology2013 May536-823649360
Models of signalling networks - what cell biologists can gain from them and give to them.Janes, Kevin A; Lauffenburger, Douglas AJournal of cell science2013 May 11913-2123720376
A mechanical design principle for tissue structure and function in the airway tree.LaPrad, Adam S; Lutchen, Kenneth R; Suki, BelaPLoS computational biology2013 Maye100308323737742
Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers.Fu, Dan; Holtom, Gary; Freudiger, Christian; Zhang, Xu; Xie, Xiaoliang SunneyThe journal of physical chemistry. B2013 Apr 254634-4023256635
Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein.Horwitz, Joshua A; Dorner, Marcus; Friling, Tamar; Donovan, Bridget M; Vogt, Alexander; Loureiro, Joana; Oh, Thomas; Rice, Charles M; Ploss, AlexanderVirology2013 Apr 2523-3323485372
The relationship between red blood cell deformability metrics and perfusion of an artificial microvascular network.Sosa, Jose M; Nielsen, Nathan D; Vignes, Seth M; Chen, Tanya G; Shevkoplyas, Sergey SClinical hemorheology and microcirculation2013 Apr 1923603326
Metalloprotein-based MRI probes.Matsumoto, Yuri; Jasanoff, AlanFEBS letters2013 Apr 171021-923376346
Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death.Kirienko, Natalia V; Kirienko, Daniel R; Larkins-Ford, Jonah; Wahlby, Carolina; Ruvkun, Gary; Ausubel, Frederick MCell host & microbe2013 Apr 17406-1623601103
Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.Teplova, Marianna; Hafner, Markus; Teplov, Dmitri; Essig, Katharina; Tuschl, Thomas; Patel, Dinshaw JGenes & development2013 Apr 15928-4023630077
Injectable, cellular-scale optoelectronics with applications for wireless optogenetics.Kim, Tae-il; McCall, Jordan G; Jung, Yei Hwan; Huang, Xian; Siuda, Edward R; Li, Yuhang; Song, Jizhou; Song, Young Min; Pao, Hsuan An; Kim, Rak-Hwan; Lu, Chaofeng; Lee, Sung Dan; Song, Il-Sun; Shin, Gunchul; Al-Hasani, Ream; Kim, Stanley; Tan, Meng Peun; Science (New York, N.Y.)2013 Apr 12211-623580530
Polymerization of a peptide-based enzyme substrate.Hahn, Michael E; Randolph, Lyndsay M; Adamiak, Lisa; Thompson, Matthew P; Gianneschi, Nathan CChemical communications (Cambridge, England)2013 Apr 112873-523450132
Peptidergic CGRPýý primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.McCoy, Eric S; Taylor-Blake, Bonnie; Street, Sarah E; Pribisko, Alaine L; Zheng, Jihong; Zylka, Mark JNeuron2013 Apr 10138-5123523592
Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway.Song, Daisheng; Li, Lin-Sheng; Heaton-Johnson, Katherine J; Arsenault, Patrick R; Master, Stephen R; Lee, Frank SThe Journal of biological chemistry2013 Apr 59662-7423413029
Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine.Park, Walter G; Wu, Manhong; Bowen, Raffick; Zheng, Ming; Fitch, William L; Pai, Reetesh K; Wodziak, Dariusz; Visser, Brendan C; Poultsides, George A; Norton, Jeff A; Banerjee, Subhas; Chen, Ann M; Friedland, Shai; Scott, Brennan A; Pasricha, Pankaj Jay; Gastrointestinal endoscopy2013 Apr 523566642
Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs.Ding, Qiurong; Regan, Stephanie N; Xia, Yulei; Oostrom, Leonie A; Cowan, Chad A; Musunuru, KiranCell stem cell2013 Apr 4393-423561441
Stacking nonenzymatic circuits for high signal gain.Chen, Xi; Briggs, Neima; McLain, Jeremy R; Ellington, Andrew DProceedings of the National Academy of Sciences of the United States of America2013 Apr 25386-9123509255
Adaptation and clonal selection models of castration-resistant prostate cancer: current perspective.Ahmed, Muhammed; Li, Long-ChengInternational journal of urology : official journal of the Japanese Urological Association2013 Apr362-7123163774
High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase.McCoy, Eric S; Lea, Wendy A; Mott, Bryan T; Maloney, David J; Jadhav, Ajit; Simeonov, Anton; Zylka, Mark JJournal of biomolecular screening2013 Apr481-923190738
High-fat diet acutely affects circadian organisation and eating behavior.Pendergast, Julie S; Branecky, Katrina L; Yang, William; Ellacott, Kate L J; Niswender, Kevin D; Yamazaki, ShinThe European journal of neuroscience2013 Apr1350-623331763
Photochemical activation of TRPA1 channels in neurons and animals.Kokel, David; Cheung, Chung Yan J; Mills, Robert; Coutinho-Budd, Jaeda; Huang, Liyi; Setola, Vincent; Sprague, Jared; Jin, Shan; Jin, Youngnam N; Huang, Xi-Ping; Bruni, Giancarlo; Woolf, Clifford J; Roth, Bryan L; Hamblin, Michael R; Zylka, Mark J; Milan,Nature chemical biology2013 Apr257-6323396078
WNT signaling in stem cell differentiation and tumor formation.Ouyang, Hong; Zhuo, Yehong; Zhang, KangThe Journal of clinical investigation2013 Apr 11422-423524963
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.Zhang, Qiang; Bhattacharya, Sudin; Andersen, Melvin EOpen biology2013 Apr13003123615029
A low-cost technique to cryo-protect and freeze rodent brains, precisely aligned to stereotaxic coordinates for whole-brain cryosectioning.Pinskiy, Vadim; Tolpygo, Alexander S; Jones, Jamie; Weber, Kevin; Franciotti, Neil; Mitra, Partha PJournal of neuroscience methods2013 Mar 2923541995
MicroRNA-276a functions in ellipsoid body and mushroom body neurons for naive and conditioned olfactory avoidance in Drosophila.Li, Wanhe; Cressy, Michael; Qin, Hongtao; Fulga, Tudor; Van Vactor, David; Dubnau, JoshThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Mar 275821-3323536094
Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer.Lee, Gee Young; Qian, Wei Ping; Wang, Liya; Wang, Yongqiang Andrew; Staley, Charles A; Satpathy, Minati; Nie, Shuming; Mao, Hui; Yang, LilyACS nano2013 Mar 262078-8923402593
Health services innovation: the time is now.Zuckerman, Barry; Margolis, Peter A; Mate, Kedar SJAMA : the journal of the American Medical Association2013 Mar 201113-423512055
Multiplexed microcolumn-based process for efficient selection of RNA aptamers.Latulippe, David R; Szeto, Kylan; Ozer, Abdullah; Duarte, Fabiana M; Kelly, Christopher V; Pagano, John M; White, Brian S; Shalloway, David; Lis, John T; Craighead, Harold GAnalytical chemistry2013 Mar 193417-2423398198
A key role for lipoic acid synthesis during Plasmodium liver stage development.Falkard, Brie; Kumar, T R Santha; Hecht, Leonie-Sophie; Matthews, Krista A; Henrich, Philipp P; Gulati, Sonia; Lewis, Rebecca E; Manary, Micah J; Winzeler, Elizabeth A; Sinnis, Photini; Prigge, Sean T; Heussler, Volker; Deschermeier, Christina; Fidock, DaCellular microbiology2013 Mar 1423490300
Direct activation of full-length proapoptotic BAK.Leshchiner, Elizaveta S; Braun, Craig R; Bird, Gregory H; Walensky, Loren DProceedings of the National Academy of Sciences of the United States of America2013 Mar 12E986-9523404709
Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions.Jagadish, Krishnappa; Borra, Radhika; Lacey, Vanessa; Majumder, Subhabrata; Shekhtman, Alexander; Wang, Lei; Camarero, Julio AAngewandte Chemie (International ed. in English)2013 Mar 113126-3123322720
Killing by bactericidal antibiotics does not depend on reactive oxygen species.Keren, Iris; Wu, Yanxia; Inocencio, Julio; Mulcahy, Lawrence R; Lewis, KimScience (New York, N.Y.)2013 Mar 81213-623471410
Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury.Xu, Zhen-Zhong; Berta, Temugin; Ji, Ru-RongJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2013 Mar37-4122878925
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells.Bhutani, Nidhi; Decker, Matthew N; Brady, Jennifer J; Bussat, Rose T; Burns, David M; Corbel, Stephane Y; Blau, Helen MFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013 Mar1107-1323212122
Endothelial cell phenotypic behaviors cluster into dynamic state transition programs modulated by angiogenic and angiostatic cytokines.Rimchala, Tharathorn; Kamm, Roger D; Lauffenburger, Douglas AIntegrative biology : quantitative biosciences from nano to macro2013 Mar510-2223303249
Modeling boundary conditions for balanced proliferation in metastatic latency.Taylor, Donald P; Wells, Jakob Z; Savol, Andrej; Chennubhotla, Chakra; Wells, AlanClinical cancer research : an official journal of the American Association for Cancer Research2013 Mar 11063-7023329811
Robust, synergistic regulation of human gene expression using TALE activators.Maeder, Morgan L; Linder, Samantha J; Reyon, Deepak; Angstman, James F; Fu, Yanfang; Sander, Jeffry D; Joung, J KeithNature methods2013 Mar243-523396285
Protein-protein interactions: A PUMA mechanism unfolds.Walensky, Loren DNature chemical biology2013 Mar141-323416398
The continuing challenge of understanding, preventing, and treating neural tube defects.Wallingford, John B; Niswander, Lee A; Shaw, Gary M; Finnell, Richard HScience (New York, N.Y.)2013 Mar 1122200223449594
Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants.Djonovic, Slavica; Urbach, Jonathan M; Drenkard, Eliana; Bush, Jenifer; Feinbaum, Rhonda; Ausubel, Jonathan L; Traficante, David; Risech, Martina; Kocks, Christine; Fischbach, Michael A; Priebe, Gregory P; Ausubel, Frederick MPLoS pathogens2013 Mare100321723505373
Simultaneous top-down modulation of the primary somatosensory cortex and thalamic nuclei during active tactile discrimination.Pais-Vieira, Miguel; Lebedev, Mikhail A; Wiest, Michael C; Nicolelis, Miguel A LThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Feb 274076-9323447616
A TALEN genome-editing system for generating human stem cell-based disease models.Ding, Qiurong; Lee, Youn-Kyoung; Schaefer, Esperance A K; Peters, Derek T; Veres, Adrian; Kim, Kevin; Kuperwasser, Nicolas; Motola, Daniel L; Meissner, Torsten B; Hendriks, William T; Trevisan, Marta; Gupta, Rajat M; Moisan, Annie; Banks, Eric; Friesen, MCell stem cell2013 Feb 7238-5123246482
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.Chen, Chia-Hung; Miller, Miles A; Sarkar, Aniruddh; Beste, Michael T; Isaacson, Keith B; Lauffenburger, Douglas A; Griffith, Linda G; Han, JongyoonJournal of the American Chemical Society2013 Feb 61645-823157326
Structural basis for conformational switching and GTP loading of the large G protein atlastin.Byrnes, Laura J; Singh, Avtar; Szeto, Kylan; Benvin, Nicole M; O'Donnell, John P; Zipfel, Warren R; Sondermann, HolgerThe EMBO journal2013 Feb 6369-8423334294
JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration.Du, Hongjun; Sun, Xufang; Guma, Monica; Luo, Jing; Ouyang, Hong; Zhang, Xiaohui; Zeng, Jing; Quach, John; Nguyen, Duy H; Shaw, Peter X; Karin, Michael; Zhang, KangProceedings of the National Academy of Sciences of the United States of America2013 Feb 52377-8223341606
Structures of a Na+-coupled, substrate-bound MATE multidrug transporter.Lu, Min; Symersky, Jindrich; Radchenko, Martha; Koide, Akiko; Guo, Yi; Nie, Rongxin; Koide, ShoheiProceedings of the National Academy of Sciences of the United States of America2013 Feb 52099-10423341609
Systems memory consolidation in Drosophila.Dubnau, Josh; Chiang, Ann-ShynCurrent opinion in neurobiology2013 Feb84-9123084099
Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interaction.Nishimura, Toshiko; Hu, Yajing; Wu, Manhong; Pham, Edward; Suemizu, Hiroshi; Elazar, Menashe; Liu, Michael; Idilman, Ramazan; Yurdaydin, Cihan; Angus, Peter; Stedman, Catherine; Murphy, Brian; Glenn, Jeffrey; Nakamura, Masato; Nomura, Tatsuji; Chen, Yuan;The Journal of pharmacology and experimental therapeutics2013 Feb388-9623143674
Emerging strategies for spatiotemporal control of stem cell fate and morphogenesis.Kinney, Melissa A; McDevitt, Todd CTrends in biotechnology2013 Feb78-8423219200
Circulating humanin levels are associated with preserved coronary endothelial function.Widmer, R J; Flammer, A J; Herrmann, J; Rodriguez-Porcel, M; Wan, J; Cohen, P; Lerman, L O; Lerman, AAmerican journal of physiology. Heart and circulatory physiology2013 Feb 1H393-723220334
The emerging role of the mitochondrial-derived peptide humanin in stress resistance.Yen, Kelvin; Lee, Changhan; Mehta, Hemal; Cohen, PinchasJournal of molecular endocrinology2013 FebR11-923239898
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Multi-disciplinary methods to define RNA-protein interactions and regulatory networks.Ascano, Manuel; Gerstberger, Stefanie; Tuschl, ThomasCurrent opinion in genetics & development2013 Feb20-823453689
The Ability of Narrative Communication to Address Health-related Social Norms.Moran, Meghan Bridgid; Murphy, Sheila T; Frank, Lauren; Baezconde-Garbanati, LourdesInternational Review of Social Research2013 Feb131-14924179677
Narrative versus Non-narrative: The Role of Identification, Transportation and Emotion in Reducing Health Disparities.Murphy, Sheila T; Frank, Lauren B; Chatterjee, Joyee S; Baezconde-Garbanati, LourdesThe Journal of communication2013 FebNULL24347679
ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps.Deindl, Sebastian; Hwang, William L; Hota, Swetansu K; Blosser, Timothy R; Prasad, Punit; Bartholomew, Blaine; Zhuang, XiaoweiCell2013 Jan 31442-5223374341
Phosphine quenching of cyanine dyes as a versatile tool for fluorescence microscopy.Vaughan, Joshua C; Dempsey, Graham T; Sun, Eileen; Zhuang, XiaoweiJournal of the American Chemical Society2013 Jan 301197-20023311875
Genome-wide methylation profiles reveal quantitative views of human aging rates.Hannum, Gregory; Guinney, Justin; Zhao, Ling; Zhang, Li; Hughes, Guy; Sadda, SriniVas; Klotzle, Brandy; Bibikova, Marina; Fan, Jian-Bing; Gao, Yuan; Deconde, Rob; Chen, Menzies; Rajapakse, Indika; Friend, Stephen; Ideker, Trey; Zhang, KangMolecular cell2013 Jan 24359-6723177740
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.Xue, Yuanchao; Ouyang, Kunfu; Huang, Jie; Zhou, Yu; Ouyang, Hong; Li, Hairi; Wang, Gang; Wu, Qijia; Wei, Chaoliang; Bi, Yanzhen; Jiang, Li; Cai, Zhiqiang; Sun, Hui; Zhang, Kang; Zhang, Yi; Chen, Ju; Fu, Xiang-DongCell2013 Jan 1782-9623313552
Two novel DEG/ENaC channel subunits expressed in glia are needed for nose-touch sensitivity in Caenorhabditis elegans.Han, Lu; Wang, Ying; Sangaletti, Rachele; D'Urso, Giulia; Lu, Yun; Shaham, Shai; Bianchi, LauraThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Jan 16936-4923325233
Multicolor stimulated Raman scattering microscopy with a rapidly tunable optical parametric oscillator.Kong, Lingjie; Ji, Minbiao; Holtom, Gary R; Fu, Dan; Freudiger, Christian W; Xie, X SunneyOptics letters2013 Jan 15145-723454943
Two methods for full-length RNA sequencing for low quantities of cells and single cells.Pan, Xinghua; Durrett, Russell E; Zhu, Haiying; Tanaka, Yoshiaki; Li, Yumei; Zi, Xiaoyuan; Marjani, Sadie L; Euskirchen, Ghia; Ma, Chao; Lamotte, Robert H; Park, In-Hyun; Snyder, Michael P; Mason, Christopher E; Weissman, Sherman MProceedings of the National Academy of Sciences of the United States of America2013 Jan 8594-923267071
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Distinct cutaneous bacterial assemblages in a sampling of South American Amerindians and US residents.Blaser, Martin J; Dominguez-Bello, Maria G; Contreras, Monica; Magris, Magda; Hidalgo, Glida; Estrada, Isidoro; Gao, Zhan; Clemente, Jose C; Costello, Elizabeth K; Knight, RobThe ISME journal2013 Jan85-9522895161
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The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics.Pipes, Lenore; Li, Sheng; Bozinoski, Marjan; Palermo, Robert; Peng, Xinxia; Blood, Phillip; Kelly, Sara; Weiss, Jeffrey M; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Zumbo, Paul; Chen, Ronghua; Schroth, Gary P; Mason, Christopher E; Katze, Michael GNucleic acids research2013 JanD906-1423203872
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Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.Cezairliyan, Brent; Vinayavekhin, Nawaporn; Grenfell-Lee, Daniel; Yuen, Grace J; Saghatelian, Alan; Ausubel, Frederick MPLoS pathogens2013 Jane100310123300454
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Antibiotic exposure and the development of coeliac disease: a nationwide case-control study.Marild, Karl; Ye, Weimin; Lebwohl, Benjamin; Green, Peter H R; Blaser, Martin J; Card, Tim; Ludvigsson, Jonas FBMC gastroenterology201310923834758
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Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia.Cheng, Heather H; Mitchell, Patrick S; Kroh, Evan M; Dowell, Alexander E; Chery, Lisly; Siddiqui, Javed; Nelson, Peter S; Vessella, Robert L; Knudsen, Beatrice S; Chinnaiyan, Arul M; Pienta, Kenneth J; Morrissey, Colm; Tewari, MuneeshPloS one2013e6923923935962
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Ferrous iron is a significant component of bioavailable iron in cystic fibrosis airways.Hunter, Ryan C; Asfour, Fadi; Dingemans, Jozef; Osuna, Brenda L; Samad, Tahoura; Malfroot, Anne; Cornelis, Pierre; Newman, Dianne KmBio2013NULL23963183
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Microglia and spinal cord synaptic plasticity in persistent pain.Taves, Sarah; Berta, Temugin; Chen, Gang; Ji, Ru-RongNeural plasticity201375365624024042
An automated microfluidic multiplexer for fast delivery of C. elegans populations from multiwells.Ghorashian, Navid; Gokce, Sertan Kutal; Guo, Sam Xun; Everett, William Neil; Ben-Yakar, AdelaPloS one2013e7448024069313
Metabolic characterization of a Sirt5 deficient mouse model.Yu, Jiujiu; Sadhukhan, Sushabhan; Noriega, Lilia G; Moullan, Norman; He, Bin; Weiss, Robert S; Lin, Hening; Schoonjans, Kristina; Auwerx, JohanScientific reports2013280624076663
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An integrated strategy for efficient vector construction and multi-gene expression in Plasmodium falciparum.Wagner, Jeffrey C; Goldfless, Stephen J; Ganesan, Suresh M; Lee, Marcus C S; Fidock, David A; Niles, Jacquin CMalaria journal201337324160265
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A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells.Zawistowski, Jon S; Sabouri-Ghomi, Mohsen; Danuser, Gaudenz; Hahn, Klaus M; Hodgson, LouisPloS one2013e7987724224016
Urinary triclosan is associated with elevated body mass index in NHANES.Lankester, Joanna; Patel, Chirag; Cullen, Mark R; Ley, Catherine; Parsonnet, JuliePloS one2013e8005724278238
RAPID-SELEX for RNA Aptamers.Szeto, Kylan; Latulippe, David R; Ozer, Abdullah; Pagano, John M; White, Brian S; Shalloway, David; Lis, John T; Craighead, Harold GPloS one2013e8266724376564
Growth pattern analysis of murine lung neoplasms by advanced semi-automated quantification of micro-CT images.Li, Minxing; Jirapatnakul, Artit; Biancardi, Alberto; Riccio, Mark L; Weiss, Robert S; Reeves, Anthony PPloS one2013e8380624376755
Visualizing cytoplasmic flow during single-cell wound healing in Stentor coeruleus.Slabodnick, Mark; Prevo, Bram; Gross, Peter; Sheung, Janet; Marshall, WallaceJournal of visualized experiments : JoVE2013e5084824378633
Multiple knockout mouse models reveal lincRNAs are required for life and brain development.Sauvageau, Martin; Goff, Loyal A; Lodato, Simona; Bonev, Boyan; Groff, Abigail F; Gerhardinger, Chiara; Sanchez-Gomez, Diana B; Hacisuleyman, Ezgi; Li, Eric; Spence, Matthew; Liapis, Stephen C; Mallard, William; Morse, Michael; Swerdel, Mavis R; D'EcclesseLife2013e0174924381249
Reducing the Excess Burden of Cervical Cancer Among Latinas: Translating Science into Health Promotion Initiatives.Baezconde-Garbanati, Lourdes; Murphy, Sheila T; Moran, Meghan Bridgid; Cortessis, Victoria KCalifornian journal of health promotion201345-5724587769
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FMRP targets distinct mRNA sequence elements to regulate protein expression.Ascano Jr, Manuel; Mukherjee, Neelanjan; Bandaru, Pradeep; Miller, Jason B; Nusbaum, Jeffrey D; Corcoran, David L; Langlois, Christine; Munschauer, Mathias; Dewell, Scott; Hafner, Markus; Williams, Zev; Ohler, Uwe; Tuschl, ThomasNature2012 Dec 20382-623235829
Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.Aboye, Teshome L; Ha, Helen; Majumder, Subhabrata; Christ, Frauke; Debyser, Zeger; Shekhtman, Alexander; Neamati, Nouri; Camarero, Julio AJournal of medicinal chemistry2012 Dec 1310729-3423151033
Pluripotent stem cells: immune to the immune system?Pearl, Jeremy I; Kean, Leslie S; Davis, Mark M; Wu, Joseph CScience translational medicine2012 Dec 12164ps2523241742
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.Levi, Benjamin; Hyun, Jeong S; Montoro, Daniel T; Lo, David D; Chan, Charles K F; Hu, Shijun; Sun, Ning; Lee, Min; Grova, Monica; Connolly, Andrew J; Wu, Joseph C; Gurtner, Geoffrey C; Weissman, Irving L; Wan, Derrick C; Longaker, Michael TProceedings of the National Academy of Sciences of the United States of America2012 Dec 1120379-8423169671
Single-round, multiplexed antibody mimetic design through mRNA display.Olson, C Anders; Nie, Jeff; Diep, Jonathan; Al-Shyoukh, Ibrahim; Takahashi, Terry T; Al-Mawsawi, Laith Q; Bolin, Jennifer M; Elwell, Angela L; Swanson, Scott; Stewart, Ron; Thomson, James A; Soh, H Tom; Roberts, Richard W; Sun, RenAngewandte Chemie (International ed. in English)2012 Dec 712449-5323125174
What's in a name generator? Choosing the right name generators for social network surveys in healthcare quality and safety research.Burt, Ronald S; Meltzer, David O; Seid, Michael; Borgert, Amy; Chung, Jeanette W; Colletti, Richard B; Dellal, George; Kahn, Stacy A; Kaplan, Heather C; Peterson, Laura E; Margolis, PeterBMJ quality & safety2012 Dec992-100022942400
Cellular reprogramming: a small molecule perspective.Nie, Baoming; Wang, Haixia; Laurent, Timothy; Ding, ShengCurrent opinion in cell biology2012 Dec784-9222959962
In vivo imaging of tracheal epithelial cells in mice during airway regeneration.Kim, Jun Ki; Vinarsky, Vladimir; Wain, John; Zhao, Rui; Jung, Keehoon; Choi, Jinwoo; Lam, Adam; Pardo-Saganta, Ana; Breton, Sylvie; Rajagopal, Jayaraj; Yun, Seok HyunAmerican journal of respiratory cell and molecular biology2012 Dec864-822984086
Identification of drug targets by chemogenomic and metabolomic profiling in yeast.Wu, Manhong; Zheng, Ming; Zhang, Weiruo; Suresh, Sundari; Schlecht, Ulrich; Fitch, William L; Aronova, Sofia; Baumann, Stephan; Davis, Ronald; St Onge, Robert; Dill, David L; Peltz, GaryPharmacogenetics and genomics2012 Dec877-8623076370
Ultrabright photoactivatable fluorophores created by reductive caging.Vaughan, Joshua C; Jia, Shu; Zhuang, XiaoweiNature methods2012 Dec1181-423103881
Unraveling the dynamics of ribosome translocation.Chen, Jin; Tsai, Albert; O'Leary, Sean E; Petrov, Alexey; Puglisi, Joseph DCurrent opinion in structural biology2012 Dec804-1423142574
Small molecules, big roles -- the chemical manipulation of stem cell fate and somatic cell reprogramming.Zhang, Yu; Li, Wenlin; Laurent, Timothy; Ding, ShengJournal of cell science2012 Dec 15609-2023420199
Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.Gehad, Ahmed E; Lichtman, Michael K; Schmults, Chrysalyne D; Teague, Jessica E; Calarese, Adam W; Jiang, Ying; Watanabe, Rei; Clark, Rachael AThe Journal of investigative dermatology2012 Nov2642-5122718118
Synthetic DNA immunogen encoding hepatitis B core antigen drives immune response in liver.Obeng-Adjei, N; Choo, D K; Saini, J; Yan, J; Pankhong, P; Parikh, A; Chu, J S; Weiner, D BCancer gene therapy2012 Nov779-8723037809
A randomized controlled trial to evaluate the effects of high-dose versus low-dose of arginine therapy on hepatic function tests in argininosuccinic aciduria.Nagamani, Sandesh C S; Shchelochkov, Oleg A; Mullins, Mary A; Carter, Susan; Lanpher, Brendan C; Sun, Qin; Kleppe, Soledad; Erez, Ayelet; O'Brian Smith, E; Marini, Juan C; Members of the Urea Cycle Disorders Consortium; Lee, BrendanMolecular genetics and metabolism2012 Nov315-2123040521
A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study.Lupo, Philip J; Chapa, Claudia; Nousome, Darryl; Duhon, Cody; Canfield, Mark A; Shaw, Gary M; Finnell, Richard H; Zhu, Huiping; National Birth Defects Prevention StudyMolecular genetics and metabolism2012 Nov592-523059057
A new way to start: nanoRNA-mediated priming of transcription initiation.Nickels, Bryce ETranscription2012 Nov 123117822
Vaccination with synthetic constructs expressing cytomegalovirus immunogens is highly T cell immunogenic in mice.Shedlock, Devon J; Talbott, Kendra T; Wu, Stephan J; Wilson, Christine M; Muthumani, Karuppiah; Boyer, Jean D; Sardesai, Niranjan Y; Awasthi, Sita; Weiner, David BHuman vaccines & immunotherapeutics2012 Nov 11668-8123151448
The birth of the Epitranscriptome: deciphering the function of RNA modifications.Saletore, Yogesh; Meyer, Kate; Korlach, Jonas; Vilfan, Igor D; Jaffrey, Samie; Mason, Christopher EGenome biology2012 Oct 3117523113984
Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells.Gold, Joseph D; Wu, Joseph CCirculation research2012 Oct 261250-223104873
GLP-1 analog attenuates cocaine reward.Graham, D L; Erreger, K; Galli, A; Stanwood, G DMolecular psychiatry2012 Oct 2323089631
A prion-mediated mechanism for memory proposed in Drosophila.Li, Wanhe; Dubnau, JoshNeuron2012 Oct 18260-223083729
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.Tesla, Rachel; Wolf, Hamilton Parker; Xu, Pin; Drawbridge, Jordan; Estill, Sandi Jo; Huntington, Paula; McDaniel, Latisha; Knobbe, Whitney; Burket, Aaron; Tran, Stephanie; Starwalt, Ruth; Morlock, Lorraine; Naidoo, Jacinth; Williams, Noelle S; Ready, JoseProceedings of the National Academy of Sciences of the United States of America2012 Oct 1617016-2123027932
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease.De Jesus-Cortes, Hector; Xu, Pin; Drawbridge, Jordan; Estill, Sandi Jo; Huntington, Paula; Tran, Stephanie; Britt, Jeremiah; Tesla, Rachel; Morlock, Lorraine; Naidoo, Jacinth; Melito, Lisa M; Wang, Gelin; Williams, Noelle S; Ready, Joseph M; McKnight, SteProceedings of the National Academy of Sciences of the United States of America2012 Oct 1617010-523027934
Intraoperative near-infrared imaging of surgical wounds after tumor resections can detect residual disease.Madajewski, Brian; Judy, Brendan F; Mouchli, Anas; Kapoor, Veena; Holt, David; Wang, May D; Nie, Shuming; Singhal, SunilClinical cancer research : an official journal of the American Association for Cancer Research2012 Oct 155741-5122932668
Immunotherapy against HPV16/18 generates potent TH1 and cytotoxic cellular immune responses.Bagarazzi, Mark L; Yan, Jian; Morrow, Matthew P; Shen, Xuefei; Parker, R Lamar; Lee, Jessica C; Giffear, Mary; Pankhong, Panyupa; Khan, Amir S; Broderick, Kate E; Knott, Christine; Lin, Feng; Boyer, Jean D; Draghia-Akli, Ruxandra; White, C Jo; Kim, J JoseScience translational medicine2012 Oct 10155ra13823052295
Regenerative medicine for the special senses: restoring the inputs.Bermingham-McDonogh, Olivia; Corwin, Jeffrey T; Hauswirth, William W; Heller, Stefan; Reed, Randall; Reh, Thomas AThe Journal of neuroscience : the official journal of the Society for Neuroscience2012 Oct 1014053-723055472
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles.Akalin, Altuna; Kormaksson, Matthias; Li, Sheng; Garrett-Bakelman, Francine E; Figueroa, Maria E; Melnick, Ari; Mason, Christopher EGenome biology2012 Oct 3R8723034086
Adapting enzyme-free DNA circuits to the detection of loop-mediated isothermal amplification reactions.Li, Bingling; Chen, Xi; Ellington, Andrew DAnalytical chemistry2012 Oct 28371-722947054
P53 is required for the developmental restriction in Muller glial proliferation in mouse retina.Ueki, Yumi; Karl, Mike O; Sudar, Samuel; Pollak, Julia; Taylor, Russell J; Loeffler, Kati; Wilken, Matthew S; Reardon, Sara; Reh, Thomas AGlia2012 Oct1579-8922777914
Variable ventilation enhances ventilation without exacerbating injury in preterm lambs with respiratory distress syndrome.Berry, Clare A; Suki, Bela; Polglase, Graeme R; Pillow, J JanePediatric research2012 Oct384-9222805999
Human endogenous retrovirus K Gag coassembles with HIV-1 Gag and reduces the release efficiency and infectivity of HIV-1.Monde, Kazuaki; Contreras-Galindo, Rafael; Kaplan, Mark H; Markovitz, David M; Ono, AkiraJournal of virology2012 Oct11194-20822855497
Acute mechanical forces cause deterioration in lung structure and function in elastase-induced emphysema.Szabari, M V; Parameswaran, H; Sato, S; Hantos, Z; Bartolak-Suki, E; Suki, BAmerican journal of physiology. Lung cellular and molecular physiology2012 Oct 1L567-7422865550
The many roads to Rome: induction of neural precursor cells from fibroblasts.Lujan, Ernesto; Wernig, MariusCurrent opinion in genetics & development2012 Oct517-2222868177
Multicolored stain-free histopathology with coherent Raman imaging.Freudiger, Christian W; Pfannl, Rolf; Orringer, Daniel A; Saar, Brian G; Ji, Minbiao; Zeng, Qing; Ottoboni, Linda; Wei, Ying; Ying, Wei; Waeber, Christian; Sims, John R; De Jager, Philip L; Sagher, Oren; Philbert, Martin A; Xu, Xiaoyin; Kesari, Santosh; XLaboratory investigation; a journal of technical methods and pathology2012 Oct1492-50222906986
Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells.Kosaka, Mika; Kang, Moo Rim; Yang, Glen; Li, Long-ChengNucleic acid therapeutics2012 Oct335-4322909100
The mouse lymph node as an ectopic transplantation site for multiple tissues.Komori, Junji; Boone, Lindsey; DeWard, Aaron; Hoppo, Toshitaka; Lagasse, EricNature biotechnology2012 Oct976-8323000933
Molecular roadblocks for cellular reprogramming.Vierbuchen, Thomas; Wernig, MariusMolecular cell2012 Sep 28827-3823020854
Measurement and modeling of signaling at the single-cell level.Kolitz, Sarah E; Lauffenburger, Douglas ABiochemistry2012 Sep 257433-4322954137
Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9.Liu, Xiaodan; Dix, Melissa; Speers, Anna E; Bachovchin, Daniel A; Zuhl, Andrea M; Cravatt, Benjamin F; Kodadek, Thomas JChembiochem : a European journal of chemical biology2012 Sep 242082-9322907802
Cell surface assembly of HIV gp41 six-helix bundles for facile, quantitative measurements of hetero-oligomeric interactions.Hu, Xuebo; Saha, Piyali; Chen, Xiaoyue; Kim, Dogeun; Devarasetty, Mahesh; Varadarajan, Raghavan; Jin, Moonsoo MJournal of the American Chemical Society2012 Sep 1214642-522888993
Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice.Zhang, Xin; Urbieta-Caceres, Victor H; Eirin, Alfonso; Bell, Caitlin C; Crane, John A; Tang, Hui; Jordan, Kyra L; Oh, Yun-Kyu; Zhu, Xiang-Yang; Korsmo, Michael J; Bachar, Adi R; Cohen, Pinchas; Lerman, Amir; Lerman, Lilach OLife sciences2012 Sep 4199-20622820173
Signaling defects in iPSC-derived fragile X premutation neurons.Liu, Jing; Koscielska, Katarzyna A; Cao, Zhengyu; Hulsizer, Susan; Grace, Natalie; Mitchell, Gaela; Nacey, Catherine; Githinji, Jackline; McGee, Jeannine; Garcia-Arocena, Dolores; Hagerman, Randi J; Nolta, Jan; Pessah, Isaac N; Hagerman, Paul JHuman molecular genetics2012 Sep 13795-80522641815
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues.Miller, Jordan S; Stevens, Kelly R; Yang, Michael T; Baker, Brendon M; Nguyen, Duc-Huy T; Cohen, Daniel M; Toro, Esteban; Chen, Alice A; Galie, Peter A; Yu, Xiang; Chaturvedi, Ritika; Bhatia, Sangeeta N; Chen, Christopher SNature materials2012 Sep768-7422751181
Role of oxidative stress in persister tolerance.Wu, Yanxia; Vulic, Marin; Keren, Iris; Lewis, KimAntimicrobial agents and chemotherapy2012 Sep4922-622777047
Single-molecule analysis of translational dynamics.Petrov, Alexey; Chen, Jin; O'Leary, Sean; Tsai, Albert; Puglisi, Joseph DCold Spring Harbor perspectives in biology2012 Sepa01155122798542
Optimizing therapy for argininosuccinic aciduria.Nagamani, Sandesh C S; Lee, Brendan; Erez, AyeletMolecular genetics and metabolism2012 Sep10-422841516
Infectious diseases in children and body mass index in young adults.Suh, Gina; Ley, Catherine; Parsonnet, JulieEmerging infectious diseases2012 Sep1490-222932124
Antibiotics in early life alter the murine colonic microbiome and adiposity.Cho, Ilseung; Yamanishi, Shingo; Cox, Laura; Methe, Barbara A; Zavadil, Jiri; Li, Kelvin; Gao, Zhan; Mahana, Douglas; Raju, Kartik; Teitler, Isabel; Li, Huilin; Alekseyenko, Alexander V; Blaser, Martin JNature2012 Aug 30621-622914093
Probing spatial organization of DNA strands using enzyme-free hairpin assembly circuits.Li, Bingling; Jiang, Yu; Chen, Xi; Ellington, Andrew DJournal of the American Chemical Society2012 Aug 2913918-2122894754
Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s).Pendergast, Julie S; Oda, Gisele A; Niswender, Kevin D; Yamazaki, ShinProceedings of the National Academy of Sciences of the United States of America2012 Aug 2814218-2322891330
DNA circuits as amplifiers for the detection of nucleic acids on a paperfluidic platform.Allen, Peter B; Arshad, Seyed A; Li, Bingling; Chen, Xi; Ellington, Andrew DLab on a chip2012 Aug 212951-822729075
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.Shaw, Peter X; Zhang, Li; Zhang, Ming; Du, Hongjun; Zhao, Ling; Lee, Clara; Grob, Seanna; Lim, Siok Lam; Hughes, Guy; Lee, Janet; Bedell, Matthew; Nelson, Mark H; Lu, Fang; Krupa, Martin; Luo, Jing; Ouyang, Hong; Tu, Zhidan; Su, Zhiguang; Zhu, Jin; Wei, XProceedings of the National Academy of Sciences of the United States of America2012 Aug 2113757-6222875704
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5).Zhou, Yeyun; Zhang, Hongmin; He, Bin; Du, Jintang; Lin, Hening; Cerione, Richard A; Hao, QuanThe Journal of biological chemistry2012 Aug 1728307-1422767592
Adventures in neurobioengineering.Jasanoff, AlanACS chemical neuroscience2012 Aug 1557522896800
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Biological synthesis of circular polypeptides.Aboye, Teshome L; Camarero, Julio AThe Journal of biological chemistry2012 Aug 327026-3222707722
Multifunctional materials through modular protein engineering.DiMarco, Rebecca L; Heilshorn, Sarah CAdvanced materials (Deerfield Beach, Fla.)2012 Aug 23923-4022730248
Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.Gonzalez-Hernandez, Marta J; Swanson, Michael D; Contreras-Galindo, Rafael; Cookinham, Sarah; King, Steven R; Noel Jr, Richard J; Kaplan, Mark H; Markovitz, David MJournal of virology2012 Aug7790-80522593154
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Antiepileptic drugs and pregnancy outcomes.Wlodarczyk, Bogdan J; Palacios, Ana M; George, Timothy M; Finnell, Richard HAmerican journal of medical genetics. Part A2012 Aug2071-9022711424
Structural insights for engineering binding proteins based on non-antibody scaffolds.Gilbreth, Ryan N; Koide, ShoheiCurrent opinion in structural biology2012 Aug413-2022749196
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Persister-promoting bacterial toxin TisB produces anion-selective pores in planar lipid bilayers.Gurnev, Philip A; Ortenberg, Ron; Dorr, Tobias; Lewis, Kim; Bezrukov, Sergey MFEBS letters2012 Jul 302529-3422728134
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Molecular architecture and assembly principles of Vibrio cholerae biofilms.Berk, Veysel; Fong, Jiunn C N; Dempsey, Graham T; Develioglu, Omer N; Zhuang, Xiaowei; Liphardt, Jan; Yildiz, Fitnat H; Chu, StevenScience (New York, N.Y.)2012 Jul 13236-922798614
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.Purwar, Rahul; Schlapbach, Christoph; Xiao, Sheng; Kang, Hong Soon; Elyaman, Wassim; Jiang, Xiaodong; Jetten, Anton M; Khoury, Samia J; Fuhlbrigge, Robert C; Kuchroo, Vijay K; Clark, Rachael A; Kupper, Thomas SNature medicine2012 Jul 8NULL22772464
Low copy expression vectors for use in Yersinia sp. and related organisms.Obrist, Markus W; Miller, Virginia LPlasmid2012 Jul33-4222445322
An image analysis toolbox for high-throughput C. elegans assays.Wahlby, Carolina; Kamentsky, Lee; Liu, Zihan H; Riklin-Raviv, Tammy; Conery, Annie L; O'Rourke, Eyleen J; Sokolnicki, Katherine L; Visvikis, Orane; Ljosa, Vebjorn; Irazoqui, Javier E; Golland, Polina; Ruvkun, Gary; Ausubel, Frederick M; Carpenter, Anne ENature methods2012 Jul714-622522656
Growth phase-dependent control of transcription start site selection and gene expression by nanoRNAs.Vvedenskaya, Irina O; Sharp, Josh S; Goldman, Seth R; Kanabar, Pinal N; Livny, Jonathan; Dove, Simon L; Nickels, Bryce EGenes & development2012 Jul 11498-50722751503
Fully functionalized small-molecule probes for integrated phenotypic screening and target identification.Cisar, Justin S; Cravatt, Benjamin FJournal of the American Chemical Society2012 Jun 2710385-822667687
Exendin-4 decreases amphetamine-induced locomotor activity.Erreger, Kevin; Davis, Adeola R; Poe, Amanda M; Greig, Nigel H; Stanwood, Gregg D; Galli, AurelioPhysiology & behavior2012 Jun 25574-822465309
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.Meyer, Kate D; Saletore, Yogesh; Zumbo, Paul; Elemento, Olivier; Mason, Christopher E; Jaffrey, Samie RCell2012 Jun 221635-4622608085
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Dual responsiveness of a tunable thermo-sensitive polypeptide.Chopko, Caroline M; Lowden, Erika L; Engler, Amanda C; Griffith, Linda G; Hammond, Paula TACS macro letters2012 Jun 19727-73124883233
Protein lysine acylation and cysteine succination by intermediates of energy metabolism.Lin, Hening; Su, Xiaoyang; He, BinACS chemical biology2012 Jun 15947-6022571489
Monitoring the temporal changes of respiratory resistance: a novel test for the management of asthma.Gulotta, Carlo; Suki, Bela; Brusasco, Vito; Pellegrino, Riccardo; Gobbi, Alessandro; Pedotti, Antonio; Dellaca, Raffaele LAmerican journal of respiratory and critical care medicine2012 Jun 151330-122707741
Cd14 SNPs regulate the innate immune response.Liu, Hong-Hsing; Hu, Yajing; Zheng, Ming; Suhoski, Megan M; Engleman, Edgar G; Dill, David L; Hudnall, Matt; Wang, Jianmei; Spolski, Rosanne; Leonard, Warren J; Peltz, GaryMolecular immunology2012 Jun112-2722445606
The impact of Helicobacter pylori on atopic disorders in childhood.Holster, I Lisanne; Vila, Anne Marie J; Caudri, Daan; den Hoed, Caroline M; Perez-Perez, Guillermo I; Blaser, Martin J; de Jongste, Johan C; Kuipers, Ernst JHelicobacter2012 Jun232-722515362
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.Liu, Tong; Berta, Temugin; Xu, Zhen-Zhong; Park, Chul-Kyu; Zhang, Ling; Lu, Ning; Liu, Qin; Liu, Yang; Gao, Yong-Jing; Liu, Yen-Chin; Ma, Qiufu; Dong, Xinzhong; Ji, Ru-RongThe Journal of clinical investigation2012 Jun 12195-20722565312
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Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells.Seneschal, Julien; Clark, Rachael A; Gehad, Ahmed; Baecher-Allan, Clare M; Kupper, Thomas SImmunity2012 May 25873-8422560445
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Somatic STAT3 mutations in large granular lymphocytic leukemia.Koskela, Hanna L M; Eldfors, Samuli; Ellonen, Pekka; van Adrichem, Arjan J; Kuusanmaki, Heikki; Andersson, Emma I; Lagstrom, Sonja; Clemente, Michael J; Olson, Thomas; Jalkanen, Sari E; Majumder, Muntasir Mamun; Almusa, Henrikki; Edgren, Henrik; Lepisto, The New England journal of medicine2012 May 171905-1322591296
Statistical deconvolution for superresolution fluorescence microscopy.Mukamel, Eran A; Babcock, Hazen; Zhuang, XiaoweiBiophysical journal2012 May 162391-40022677393
Concentration- and stage-specific effects of nitrite on colon cancer cell lines.Jiang, Hong; Tang, Yaoping; Garg, Harsha K; Parthasarathy, Deepa K; Torregrossa, Ashley C; Hord, Norman G; Bryan, Nathan SNitric oxide : biology and chemistry / official journal of the Nitric Oxide Society2012 May 15267-7322504070
Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria.Nagamani, Sandesh C S; Campeau, Philippe M; Shchelochkov, Oleg A; Premkumar, Muralidhar H; Guse, Kilian; Brunetti-Pierri, Nicola; Chen, Yuqing; Sun, Qin; Tang, Yaoping; Palmer, Donna; Reddy, Anilkumar K; Li, Li; Slesnick, Timothy C; Feig, Daniel I; CaudleAmerican journal of human genetics2012 May 4836-4622541557
A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry.Simpson, Levi S; Kodadek, ThomasTetrahedron letters2012 May 22341-234422736872
Argininosuccinate lyase deficiency.Nagamani, Sandesh C S; Erez, Ayelet; Lee, BrendanGenetics in medicine : official journal of the American College of Medical Genetics2012 May501-722241104
Disruption of TNF-ýý/TNFR1 function in resident skin cells impairs host immune response against cutaneous vaccinia virus infection.Tian, Tian; Dubin, Krista; Jin, Qiushuang; Qureshi, Ali; King, Sandra L; Liu, Luzheng; Jiang, Xiaodong; Murphy, George F; Kupper, Thomas S; Fuhlbrigge, Robert CThe Journal of investigative dermatology2012 May1425-3422318381
Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation.Wang, Xiaoling; Wang, Ji; Huang, Vera; Place, Robert F; Li, Long-ChengThe Biochemical journal2012 May 1821-822339500
Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns.Sanchez-Freire, Veronica; Ebert, Antje D; Kalisky, Tomer; Quake, Stephen R; Wu, Joseph CNature protocols2012 May829-3822481529
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Development of humanized mouse models to study human malaria parasite infection.Vaughan, Ashley M; Kappe, Stefan H I; Ploss, Alexander; Mikolajczak, Sebastian AFuture microbiology2012 May657-6522568719
G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Hwangpo, Tracy Anh; Jordan, J Dedrick; Premsrirut, Prem K; Jayamaran, Gomathi; Licht, Jonathan D; Iyengar, Ravi; Neves, Susana RThe Journal of biological chemistry2012 Apr 2013674-8522383529
Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans.McEwan, Deborah L; Kirienko, Natalia V; Ausubel, Frederick MCell host & microbe2012 Apr 19364-7422520464
Efficient one-pot cyclization/folding of Rhesus ýý-defensin-1 (RTD-1).Aboye, Teshome L; Li, Yilong; Majumder, Subhabrata; Hao, Jinfeng; Shekhtman, Alexander; Camarero, Julio ABioorganic & medicinal chemistry letters2012 Apr 152823-622425570
Association between gastric Helicobacter pylori colonization and glycated hemoglobin levels.Chen, Yu; Blaser, Martin JThe Journal of infectious diseases2012 Apr 151195-20222427676
Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma.Cedeno-Laurent, Filiberto; Watanabe, Rei; Teague, Jessica E; Kupper, Thomas S; Clark, Rachael A; Dimitroff, Charles JBlood2012 Apr 123534-822383798
In-cell fluorescence activation and labeling of proteins mediated by FRET-quenched split inteins.Borra, Radhika; Dong, Dezheng; Elnagar, Ahmed Y; Woldemariam, Getachew A; Camarero, Julio AJournal of the American Chemical Society2012 Apr 116344-5322404648
Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers.Aguado, Brian A; Mulyasasmita, Widya; Su, James; Lampe, Kyle J; Heilshorn, Sarah CTissue engineering. Part A2012 Apr806-1522011213
Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain.Serhan, Charles N; Dalli, Jesmond; Karamnov, Sergey; Choi, Alexander; Park, Chul-Kyu; Xu, Zhen-Zhong; Ji, Ru-Rong; Zhu, Min; Petasis, Nicos AFASEB journal : official publication of the Federation of American Societies for Experimental Biology2012 Apr1755-6522253477
Sensory organ remodeling in Caenorhabditis elegans requires the zinc-finger protein ZTF-16.Procko, Carl; Lu, Yun; Shaham, ShaiGenetics2012 Apr1405-1522298710
Short small-interfering RNAs produce interferon-ýý-mediated analgesia.Tan, P H; Gao, Y J; Berta, T; Xu, Z Z; Ji, R RBritish journal of anaesthesia2012 Apr662-922307241
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Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats.Deng, Wen-Tao; Dinculescu, Astra; Li, Qiuhong; Boye, Sanford L; Li, Jie; Gorbatyuk, Marina S; Pang, Jijing; Chiodo, Vince A; Matthes, Michael T; Yasumura, Douglas; Liu, Li; Alkuraya, Fowzan S; Zhang, Kang; Vollrath, Douglas; LaVail, Matthew M; Hauswirth, Investigative ophthalmology & visual science2012 Apr1895-90422408006
The human microbiome: at the interface of health and disease.Cho, Ilseung; Blaser, Martin JNature reviews. Genetics2012 Apr260-7022411464
Improved outcomes in a quality improvement collaborative for pediatric inflammatory bowel disease.Crandall, Wallace V; Margolis, Peter A; Kappelman, Michael D; King, Eileen C; Pratt, Jesse M; Boyle, Brendan M; Duffy, Lynn F; Grunow, John E; Kim, Sandra C; Leibowitz, Ian; Schoen, Bess T; Colletti, Richard B; ImproveCareNow CollaborativePediatrics2012 Apre1030-4122412030
Emerging role of Toll-like receptors in the control of pain and itch.Liu, Tong; Gao, Yong-Jing; Ji, Ru-RongNeuroscience bulletin2012 Apr131-4422466124
Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice.Liu, Tong; Ji, Ru-RongNeuroscience bulletin2012 Apr145-5422466125
Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function.Harkewicz, Richard; Du, Hongjun; Tong, Zongzhong; Alkuraya, Hisham; Bedell, Matthew; Sun, Woong; Wang, Xiaolei; Hsu, Yuan-Hao; Esteve-Rudd, Julian; Hughes, Guy; Su, Zhiguang; Zhang, Ming; Lopes, Vanda S; Molday, Robert S; Williams, David S; Dennis, EdwardThe Journal of biological chemistry2012 Mar 3011469-8022199362
Competitive activity-based protein profiling identifies aza-ýý-lactams as a versatile chemotype for serine hydrolase inhibition.Zuhl, Andrea M; Mohr, Justin T; Bachovchin, Daniel A; Niessen, Sherry; Hsu, Ku-Lung; Berlin, Jacob M; Dochnahl, Maximilian; Lopez-Alberca, Maria P; Fu, Gregory C; Cravatt, Benjamin FJournal of the American Chemical Society2012 Mar 215068-7122400490
Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries.Aditya, Animesh; Kodadek, ThomasACS combinatorial science2012 Mar 12164-922320121
Fluorescence imaging of cellular metabolites with RNA.Paige, Jeremy S; Nguyen-Duc, Thinh; Song, Wenjiao; Jaffrey, Samie RScience (New York, N.Y.)2012 Mar 9119422403384
Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.Jiang, Xiaodong; Clark, Rachael A; Liu, Luzheng; Wagers, Amy J; Fuhlbrigge, Robert C; Kupper, Thomas SNature2012 Mar 8227-3122388819
Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin.Olson, Scott D; Kambal, Amal; Pollock, Kari; Mitchell, Gaela-Marie; Stewart, Heather; Kalomoiris, Stefanos; Cary, Whitney; Nacey, Catherine; Pepper, Karen; Nolta, Jan AMolecular and cellular neurosciences2012 Mar271-8122198539
Delivery of membrane impermeable cargo into CHO cells by peptide nanoparticles targeted by a protein corona.Dittrich, Christian; Burckhardt, Christoph J; Danuser, GaudenzBiomaterials2012 Mar2746-5322226586
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Old and new: recent innovations in vaccine biology and skin T cells.Kupper, Thomas SThe Journal of investigative dermatology2012 Mar829-3422237702
Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass.Guan, Min; Yao, Wei; Liu, Ruiwu; Lam, Kit S; Nolta, Jan; Jia, Junjing; Panganiban, Brian; Meng, Liping; Zhou, Ping; Shahnazari, Mohammad; Ritchie, Robert O; Lane, Nancy ENature medicine2012 Mar456-6222306732
miRNA goes nuclear.Huang, Vera; Li, Long-ChengRNA biology2012 Mar269-7322336708
Label-free live-cell imaging of nucleic acids using stimulated Raman scattering microscopy.Zhang, Xu; Roeffaers, Maarten B J; Basu, Srinjan; Daniele, Joseph R; Fu, Dan; Freudiger, Christian W; Holtom, Gary R; Xie, X SunneyChemphyschem : a European journal of chemical physics and physical chemistry2012 Mar1054-922368112
Quantitative chemical imaging with multiplex stimulated Raman scattering microscopy.Fu, Dan; Lu, Fa-Ke; Zhang, Xu; Freudiger, Christian; Pernik, Douglas R; Holtom, Gary; Xie, Xiaoliang SunneyJournal of the American Chemical Society2012 Feb 293623-622316340
Fully automated cellular-resolution vertebrate screening platform with parallel animal processing.Chang, Tsung-Yao; Pardo-Martin, Carlos; Allalou, Amin; Wahlby, Carolina; Yanik, Mehmet FatihLab on a chip2012 Feb 21711-622159032
AMP is an adenosine A1 receptor agonist.Rittiner, Joseph E; Korboukh, Ilia; Hull-Ryde, Emily A; Jin, Jian; Janzen, William P; Frye, Stephen V; Zylka, Mark JThe Journal of biological chemistry2012 Feb 175301-922215671
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells.Lujan, Ernesto; Chanda, Soham; Ahlenius, Henrik; Sudhof, Thomas C; Wernig, MariusProceedings of the National Academy of Sciences of the United States of America2012 Feb 142527-3222308465
Modeling hepatitis C virus infection using human induced pluripotent stem cells.Schwartz, Robert E; Trehan, Kartik; Andrus, Linda; Sheahan, Timothy P; Ploss, Alexander; Duncan, Stephen A; Rice, Charles M; Bhatia, Sangeeta NProceedings of the National Academy of Sciences of the United States of America2012 Feb 142544-822308485
Upregulation of Cyclin B1 by miRNA and its implications in cancer.Huang, Vera; Place, Robert F; Portnoy, Victoria; Wang, Ji; Qi, Zhongxia; Jia, Zhejun; Yu, Angela; Shuman, Marc; Yu, Jingwei; Li, Long-ChengNucleic acids research2012 Feb1695-70722053081
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Some, but not all, retromer components promote morphogenesis of C. elegans sensory compartments.Oikonomou, Grigorios; Perens, Elliot A; Lu, Yun; Shaham, ShaiDevelopmental biology2012 Feb 142-922138055
Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease.Olson, Scott D; Pollock, Kari; Kambal, Amal; Cary, Whitney; Mitchell, Gaela-Marie; Tempkin, Jeremy; Stewart, Heather; McGee, Jeannine; Bauer, Gerhard; Kim, Hyun Sook; Tempkin, Teresa; Wheelock, Vicki; Annett, Geralyn; Dunbar, Gary; Nolta, Jan AMolecular neurobiology2012 Feb87-9822161544
Computational methods and challenges for large-scale circuit mapping.Helmstaedter, Moritz; Mitra, Partha PCurrent opinion in neurobiology2012 Feb162-922221862
Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton.Xu, Ke; Babcock, Hazen P; Zhuang, XiaoweiNature methods2012 Feb185-822231642
Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium.Pukkila-Worley, Read; Ausubel, Frederick MCurrent opinion in immunology2012 Feb3-922236697
Anchoring molecular chromophores to colloidal gold nanocrystals: surface-enhanced Raman evidence for strong electronic coupling and irreversible structural locking.Qian, Ximei; Emory, Steven R; Nie, ShumingJournal of the American Chemical Society2012 Feb 12000-322257217
Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients.Clark, Rachael A; Watanabe, Rei; Teague, Jessica E; Schlapbach, Christoph; Tawa, Marianne C; Adams, Natalie; Dorosario, Andrew A; Chaney, Keri S; Cutler, Corey S; Leboeuf, Nicole R; Carter, Joi B; Fisher, David C; Kupper, Thomas SScience translational medicine2012 Jan 18117ra722261031
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.Koide, Akiko; Wojcik, John; Gilbreth, Ryan N; Hoey, Robert J; Koide, ShoheiJournal of molecular biology2012 Jan 13393-40522198408
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons.Huang, Hsien-Sung; Allen, John A; Mabb, Angela M; King, Ian F; Miriyala, Jayalakshmi; Taylor-Blake, Bonnie; Sciaky, Noah; Dutton Jr, J Walter; Lee, Hyeong-Min; Chen, Xin; Jin, Jian; Bridges, Arlene S; Zylka, Mark J; Roth, Bryan L; Philpot, Benjamin DNature2012 Jan 12185-922190039
Expanding the rule set of DNA circuitry with associative toehold activation.Chen, XiJournal of the American Chemical Society2012 Jan 11263-7122129141
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations.Yan, Kelley S; Chia, Luis A; Li, Xingnan; Ootani, Akifumi; Su, James; Lee, Josephine Y; Su, Nan; Luo, Yuling; Heilshorn, Sarah C; Amieva, Manuel R; Sangiorgi, Eugenio; Capecchi, Mario R; Kuo, Calvin JProceedings of the National Academy of Sciences of the United States of America2012 Jan 10466-7122190486
High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-ýý family member growth differentiation factor 6.Zhang, Li; Lim, Siok Lam; Du, Hongjun; Zhang, Ming; Kozak, Igor; Hannum, Gregory; Wang, Xiaolei; Ouyang, Hong; Hughes, Guy; Zhao, Ling; Zhu, Xuemei; Lee, Clara; Su, Zhiguang; Zhou, Xinrong; Shaw, Robert; Geum, Dongho; Wei, Xinran; Zhu, Jin; Ideker, Trey; The Journal of biological chemistry2012 Jan 61520-622049084
Modeling of spatially-restricted intracellular signaling.Neves, Susana RWiley interdisciplinary reviews. Systems biology and medicine2012 Jan-Feb103-1521766466
Systems biology of kidney diseases.He, John Cijiang; Chuang, Peter Y; Ma'ayan, Avi; Iyengar, RaviKidney international2012 Jan22-3921881558
Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: progress toward safe clinical products.Jung, Yunjoon; Bauer, Gerhard; Nolta, Jan AStem cells (Dayton, Ohio)2012 Jan42-721898694
Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals.Contreras-Galindo, Rafael; Kaplan, Mark H; Contreras-Galindo, Angie C; Gonzalez-Hernandez, Marta J; Ferlenghi, Ilaria; Giusti, Fabiola; Lorenzo, Eric; Gitlin, Scott D; Dosik, Michael H; Yamamura, Yasuhiro; Markovitz, David MJournal of virology2012 Jan262-7622031938
Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling.Shkreli, Marina; Sarin, Kavita Y; Pech, Matthew F; Papeta, Natalia; Chang, Woody; Brockman, Stephanie A; Cheung, Peggie; Lee, Eunice; Kuhnert, Frank; Olson, Jean L; Kuo, Calvin J; Gharavi, Ali G; D'Agati, Vivette D; Artandi, Steven ENature medicine2012 Jan111-922138751
The pharmacological landscape and therapeutic potential of serine hydrolases.Bachovchin, Daniel A; Cravatt, Benjamin FNature reviews. Drug discovery2012 Jan52-6822212679
A transcription activator-like effector toolbox for genome engineering.Sanjana, Neville E; Cong, Le; Zhou, Yang; Cunniff, Margaret M; Feng, Guoping; Zhang, FengNature protocols2012 Jan171-9222222791
Target-binding proteins based on the 10th human fibronectin type III domain (ýýýýýFn3).Koide, Shohei; Koide, Akiko; Lipovsek, DasaMethods in enzymology2012135-5622230568
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Novel strategy for selection of monoclonal antibodies against highly conserved antigens: phage library panning against ephrin-B2 displayed on yeast.Gu, Xiaoling; Vedvyas, Yogindra; Chen, Xiaoyue; Kaushik, Tanwi; Hwang, Chang-Il; Hu, Xuebo; Nikitin, Alexander Y; Jin, Moonsoo MPloS one2012e3068022292016
Humanin, a cytoprotective peptide, is expressed in carotid atherosclerotic [corrected] plaques in humans.Zacharias, David G; Kim, Sung Gyun; Massat, Alfonso Eirin; Bachar, Adi R; Oh, Yun K; Herrmann, Joerg; Rodriguez-Porcel, Martin; Cohen, Pinchas; Lerman, Lilach O; Lerman, AmirPloS one2012e3106522328926
Moving beyond "good fat, bad fat": the complex roles of dietary lipids in cellular function and health: session abstracts.Abumrad, Nada A; Piomelli, Daniele; Yurko-Mauro, Karin; Merrill, Alfred; Clandinin, M Tom; Serhan, Charles NAdvances in nutrition (Bethesda, Md.)2012 Jan60-822332103
Secretion and N-linked glycosylation are required for prostatic acid phosphatase catalytic and antinociceptive activity.Hurt, Julie K; Fitzpatrick, Brendan J; Norris-Drouin, Jacqueline; Zylka, Mark JPloS one2012e3274122389722
Acute morphine activates satellite glial cells and up-regulates IL-1ýý in dorsal root ganglia in mice via matrix metalloprotease-9.Berta, Temugin; Liu, Tong; Liu, Yen-Chin; Xu, Zhen-Zhong; Ji, Ru-RongMolecular pain20121822439811
Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice.Liu, Yen-Chin; Berta, Temugin; Liu, Tong; Tan, Ping-Heng; Ji, Ru-RongMolecular pain20121922444868
PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain.Hurt, Julie K; Zylka, Mark JMolecular pain20122822524543
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Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model.Limmer, Stefanie; Haller, Samantha; Drenkard, Eliana; Lee, Janice; Yu, Shen; Kocks, Christine; Ausubel, Frederick M; Ferrandon, DominiqueProceedings of the National Academy of Sciences of the United States of America2011 Oct 1817378-8321987808
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Helicobacter pylori and the birth cohort effect: evidence for stabilized colonization rates in childhood.den Hoed, Caroline M; Vila, Anne J; Holster, Ingrid L; Perez-Perez, Guillermo I; Blaser, Martin J; de Jongste, Johan C; Kuipers, Ernest JHelicobacter2011 Oct405-921923687
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Chromosome organization by a nucleoid-associated protein in live bacteria.Wang, Wenqin; Li, Gene-Wei; Chen, Chongyi; Xie, X Sunney; Zhuang, XiaoweiScience (New York, N.Y.)2011 Sep 91445-921903814
Resolvins are potent analgesics for arthritic pain.Xu, Zhen-Zhong; Ji, Ru-RongBritish journal of pharmacology2011 Sep274-721418190
Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors.Gray, Steven J; Foti, Stacey B; Schwartz, Joel W; Bachaboina, Lavanya; Taylor-Blake, Bonnie; Coleman, Jennifer; Ehlers, Michael D; Zylka, Mark J; McCown, Thomas J; Samulski, R JudeHuman gene therapy2011 Sep1143-5321476867
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A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog.Nacev, Benjamin A; Low, Woon-Kai; Huang, Zhennian; Su, Tina T; Su, Zhuang; Alkuraya, Hisham; Kasuga, Dan; Sun, Woong; Trager, Mario; Braun, Manfred; Fischer, Gunter; Zhang, Kang; Liu, Jun OThe Journal of pharmacology and experimental therapeutics2011 Aug466-7521562139
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Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells.Ghosh, Zhumur; Huang, Mei; Hu, Shijun; Wilson, Kitchener D; Dey, Devaveena; Wu, Joseph CCancer research2011 Jul 155030-921646469
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Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.Garner, Ethan C; Bernard, Remi; Wang, Wenqin; Zhuang, Xiaowei; Rudner, David Z; Mitchison, TimScience (New York, N.Y.)2011 Jul 8222-521636745
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Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors.Adibekian, Alexander; Martin, Brent R; Wang, Chu; Hsu, Ku-Lung; Bachovchin, Daniel A; Niessen, Sherry; Hoover, Heather; Cravatt, Benjamin FNature chemical biology2011 Jul469-7821572424
Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments.Hao, Limin; Thein, Melanie; Brust-Mascher, Ingrid; Civelekoglu-Scholey, Gul; Lu, Yun; Acar, Seyda; Prevo, Bram; Shaham, Shai; Scholey, Jonathan MNature cell biology2011 Jul790-821642982
Coherent Raman scanning fiber endoscopy.Saar, Brian G; Johnston, Richard S; Freudiger, Christian W; Xie, X Sunney; Seibel, Eric JOptics letters2011 Jul 12396-821725423
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A genetically humanized mouse model for hepatitis C virus infection.Dorner, Marcus; Horwitz, Joshua A; Robbins, Justin B; Barry, Walter T; Feng, Qian; Mu, Kathy; Jones, Christopher T; Schoggins, John W; Catanese, Maria Teresa; Burton, Dennis R; Law, Mansun; Rice, Charles M; Ploss, AlexanderNature2011 Jun 9208-1121654804
Imaging drug delivery to skin with stimulated Raman scattering microscopy.Saar, Brian G; Contreras-Rojas, L Rodrigo; Xie, X Sunney; Guy, Richard HMolecular pharmaceutics2011 Jun 6969-7521548600
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Glucan particles for selective delivery of siRNA to phagocytic cells in mice.Tesz, Gregory J; Aouadi, Myriam; Prot, Matthieu; Nicoloro, Sarah M; Boutet, Emilie; Amano, Shinya U; Goller, Anca; Wang, Mengxi; Guo, Chang-An; Salomon, William E; Virbasius, Joseph V; Baum, Rebecca A; O'Connor Jr, Mark J; Soto, Ernesto; Ostroff, Gary R; The Biochemical journal2011 Jun 1351-6221418037
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Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rýý(null) humanized mice.Billerbeck, Eva; Barry, Walter T; Mu, Kathy; Dorner, Marcus; Rice, Charles M; Ploss, AlexanderBlood2011 Mar 173076-8621252091
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Photoreactive stapled BH3 peptides to dissect the BCL-2 family interactome.Braun, Craig R; Mintseris, Julian; Gavathiotis, Evripidis; Bird, Gregory H; Gygi, Steven P; Walensky, Loren DChemistry & biology2010 Dec 221325-3321168768
Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration.Wang, Ji; Place, Robert F; Huang, Vera; Wang, Xiaoling; Noonan, Emily J; Magyar, Clara E; Huang, Jiaoti; Li, Long-ChengCancer research2010 Dec 1510182-9121159640
Quantitative reactivity profiling predicts functional cysteines in proteomes.Weerapana, Eranthie; Wang, Chu; Simon, Gabriel M; Richter, Florian; Khare, Sagar; Dillon, Myles B D; Bachovchin, Daniel A; Mowen, Kerri; Baker, David; Cravatt, Benjamin FNature2010 Dec 9790-521085121
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Video-rate molecular imaging in vivo with stimulated Raman scattering.Saar, Brian G; Freudiger, Christian W; Reichman, Jay; Stanley, C Michael; Holtom, Gary R; Xie, X SunneyScience (New York, N.Y.)2010 Dec 31368-7021127249
WATER, ENERGY AND LIFE: FRESH VIEWS FROM THE WATER'S EDGE.Pollack, G HInternational journal of design & nature and ecodynamics : a transdisciplinary journal relating to nature, science and the humanities2010 Dec 327-2922977460
Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis.Mulcahy, Lawrence R; Burns, Jane L; Lory, Stephen; Lewis, KimJournal of bacteriology2010 Dec6191-920935098
Helicobacter pylori and esophageal disease: wake-up call?Blaser, Martin JGastroenterology2010 Dec1819-2221029801
Toll-like receptor 7 mediates pruritus.Liu, Tong; Xu, Zhen-Zhong; Park, Chul-Kyu; Berta, Temugin; Ji, Ru-RongNature neuroscience2010 Dec1460-221037581
Importance of controlling nanotube density for highly sensitive and reliable biosensors functional in physiological conditions.Ishikawa, Fumiaki N; Curreli, Marco; Olson, C Anders; Liao, Hsiang-I; Sun, Ren; Roberts, Richard W; Cote, Richard J; Thompson, Mark E; Zhou, ChongwuACS nano2010 Nov 236914-2221028792
Spinal injection of TNF-ýý-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.Gao, Yong-Jing; Zhang, Ling; Ji, Ru-RongGlia2010 Nov 151871-8020737477
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Biological activities of natural and engineered cyclotides, a novel molecular scaffold for peptide-based therapeutics.Garcia, Angie E; Camarero, Julio ACurrent molecular pharmacology2010 Nov 1153-6320858197
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Using T. brucei as a biological epitope-display platform to elicit specific antibody responses.Stavropoulos, Pete; Papavasiliou, F NinaJournal of immunological methods2010 Oct 31190-420800596
Epistatic relationships reveal the functional organization of yeast transcription factors.Zheng, Jiashun; Benschop, Joris J; Shales, Michael; Kemmeren, Patrick; Greenblatt, Jack; Cagney, Gerard; Holstege, Frank; Li, Hao; Krogan, Nevan JMolecular systems biology2010 Oct 542020959818
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Self-assembled nanoplatform for targeted delivery of chemotherapy agents via affinity-regulated molecular interactions.Park, Spencer; Kang, Sungkwon; Veach, Alexander J; Vedvyas, Yogindra; Zarnegar, Rasa; Kim, Ju-Young; Jin, Moonsoo MBiomaterials2010 Oct7766-7520667589
Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia.Gao, Yong-Jing; Ji, Ru-RongJournal of neurochemistry2010 Oct505-1420722971
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Advances and challenges in studying hepatitis C virus in its native environment.Sheahan, Timothy; Jones, Christopher T; Ploss, AlexanderExpert review of gastroenterology & hepatology2010 Oct541-5020932139
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Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin.Puttamadappa, Shadakshara S; Jagadish, Krishnappa; Shekhtman, Alexander; Camarero, Julio AAngewandte Chemie (International ed. in English)2010 Sep 177030-420715250
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Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate.Sowa, Nathaniel A; Street, Sarah E; Vihko, Pirkko; Zylka, Mark JThe Journal of neuroscience : the official journal of the Society for Neuroscience2010 Aug 410282-9320685973
High-throughput in vivo vertebrate screening.Pardo-Martin, Carlos; Chang, Tsung-Yao; Koo, Bryan Kyo; Gilleland, Cody L; Wasserman, Steven C; Yanik, Mehmet FatihNature methods2010 Aug634-620639868
Defining features and exploring chemical modifications to manipulate RNAa activity.Place, Robert F; Noonan, Emily J; Foldes-Papp, Zeno; Li, Long-ChengCurrent pharmaceutical biotechnology2010 Aug518-2620662764
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Photomodulation of protein trans-splicing through backbone photocaging of the DnaE split intein.Berrade, Luis; Kwon, Youngeun; Camarero, Julio AChembiochem : a European journal of chemical biology2010 Jul 51368-7220512791
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DNA vaccines for targeting bacterial infections.Ingolotti, Mariana; Kawalekar, Omkar; Shedlock, Devon J; Muthumani, Karuppiah; Weiner, David BExpert review of vaccines2010 Jul747-6320624048
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In vivo biosynthesis of an Ala-scan library based on the cyclic peptide SFTI-1.Austin, Jeffrey; Kimura, Richard H; Woo, Youn-Hi; Camarero, Julio AAmino acids2010 May1313-2219685144
Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.Xu, Zhen-Zhong; Zhang, Ling; Liu, Tong; Park, Jong Yeon; Berta, Temugin; Yang, Rong; Serhan, Charles N; Ji, Ru-RongNature medicine2010 May592-7, 1p following 59720383154
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Chemokines, neuronal-glial interactions, and central processing of neuropathic pain.Gao, Yong-Jing; Ji, Ru-RongPharmacology & therapeutics2010 Apr56-6820117131
Rational conversion of affinity reagents into label-free sensors for Peptide motifs by designed allostery.Huang, Jin; Koide, ShoheiACS chemical biology2010 Mar 19273-720143785
Ki-67 staining for determination of rhesus macaque T cell proliferative responses ex vivo.Shedlock, Devon J; Talbott, Kendra T; Morrow, Matthew P; Ferraro, Bernadette; Hokey, David A; Muthumani, Karuppiah; Weiner, David BCytometry. Part A : the journal of the International Society for Analytical Cytology2010 Mar275-8420104580
New horizons for studying human hepatotropic infections.de Jong, Ype P; Rice, Charles M; Ploss, AlexanderThe Journal of clinical investigation2010 Mar650-320179350
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures.Ploss, Alexander; Khetani, Salman R; Jones, Christopher T; Syder, Andrew J; Trehan, Kartik; Gaysinskaya, Valeriya A; Mu, Kathy; Ritola, Kimberly; Rice, Charles M; Bhatia, Sangeeta NProceedings of the National Academy of Sciences of the United States of America2010 Feb 163141-520133632
Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits.Sowa, Nathaniel A; Taylor-Blake, Bonnie; Zylka, Mark JThe Journal of neuroscience : the official journal of the Society for Neuroscience2010 Feb 102235-4420147550
The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition.Gao, Yong-Jing; Xu, Zhen-Zhong; Liu, Yen-Chin; Wen, Yeong-Ray; Decosterd, Isabelle; Ji, Ru-RongPain2010 Feb309-1920022176
Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system.Jones, Christopher T; Catanese, Maria Teresa; Law, Lok Man J; Khetani, Salman R; Syder, Andrew J; Ploss, Alexander; Oh, Thomas S; Schoggins, John W; MacDonald, Margaret R; Bhatia, Sangeeta N; Rice, Charles MNature biotechnology2010 Feb167-7120118917
Antisense gets a grip on miR-122 in chimpanzees.Branch, Andrea D; Rice, Charles MScience translational medicine2010 Jan 613ps120371461
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Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells.Ghosh, Zhumur; Wilson, Kitchener D; Wu, Yi; Hu, Shijun; Quertermous, Thomas; Wu, Joseph CPloS one2010e897520126639
Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation.Sowa, Nathaniel A; Voss, Meagen K; Zylka, Mark JMolecular pain20102020398264
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.Siuta, Michael A; Robertson, Sabrina D; Kocalis, Heidi; Saunders, Christine; Gresch, Paul J; Khatri, Vivek; Shiota, Chiyo; Kennedy, J Philip; Lindsley, Craig W; Daws, Lynette C; Polley, Daniel B; Veenstra-Vanderweele, Jeremy; Stanwood, Gregg D; Magnuson, PLoS biology2010e100039320543991
Cyclotides, a promising molecular scaffold for peptide-based therapeutics.Jagadish, Krishnappa; Camarero, Julio ABiopolymers2010611-620564025
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Growth factor regulation of proliferation and survival of multipotential stromal cells.Rodrigues, Melanie; Griffith, Linda G; Wells, AlanStem cell research & therapy20103220977782
NGSQC: cross-platform quality analysis pipeline for deep sequencing data.Dai, Manhong; Thompson, Robert C; Maher, Christopher; Contreras-Galindo, Rafael; Kaplan, Mark H; Markovitz, David M; Omenn, Gil; Meng, FanBMC genomics2010S721143816
Long-range attraction in aqueous colloidal suspensions.Zhao, Qing; Coult, Jason; Pollack, Gerald HProceedings of SPIE201073761C1-73761C1322065648
A peptide tag system for facile purification and single-molecule immobilization.Huang, Jin; Nagy, Stanislav S; Koide, Akiko; Rock, Ronald S; Koide, ShoheiBiochemistry2009 Dec 2211834-619928925
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Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I.Austin, Jeffrey; Wang, Wan; Puttamadappa, Swamy; Shekhtman, Alexander; Camarero, Julio AChembiochem : a European journal of chemical biology2009 Nov 22663-7019780078
Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.Huang, Jin; Makabe, Koki; Biancalana, Matthew; Koide, Akiko; Koide, ShoheiJournal of molecular biology2009 Oct 91221-3119646997
"Splicing up" drug discovery. Cell-based expression and screening of genetically-encoded libraries of backbone-cyclized polypeptides.Sancheti, Harshkumar; Camarero, Julio AAdvanced drug delivery reviews2009 Sep 30908-1719628015
Systemic hypertension in two patients with ASL deficiency: a result of nitric oxide deficiency?Brunetti-Pierri, Nicola; Erez, Ayelet; Shchelochkov, Oleg; Craigen, William; Lee, BrendanMolecular genetics and metabolism2009 Sep-Oct195-719592285
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High-power picosecond fiber source for coherent Raman microscopy.Kieu, Khanh; Saar, Brian G; Holtom, Gary R; Xie, X Sunney; Wise, Frank WOptics letters2009 Jul 12051-319571996
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.Ootani, Akifumi; Li, Xingnan; Sangiorgi, Eugenio; Ho, Quoc T; Ueno, Hiroo; Toda, Shuji; Sugihara, Hajime; Fujimoto, Kazuma; Weissman, Irving L; Capecchi, Mario R; Kuo, Calvin JNature medicine2009 Jun701-619398967
Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury.Suter, Marc R; Berta, Temugin; Gao, Yong-Jing; Decosterd, Isabelle; Ji, Ru-RongMolecular pain20095319772627
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Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus.Muthumani, Karuppiah; Lankaraman, Katthikbabu M; Laddy, Dominick J; Sundaram, Senthil G; Chung, Christopher W; Sako, Eric; Wu, Ling; Khan, Amir; Sardesai, Niranjan; Kim, Joseph J; Vijayachari, Paluru; Weiner, David BVaccine2008 Sep 195128-3418471943


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