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Science News

• Large, Medically Important Class of Proteins Starts to Yield Its Secrets
  July 12, 2012
  Five recent Science and Nature papers shed light on elusive GPCRs.
  
  
• Team led by Scripps Research Institute Scientists Finds Atomic Structure of Molecule that Binds Opioids in the Brain
  March 21, 2012
  Scientists have for the first time determined the three-dimensional atomic structure of a human opioid receptor, a molecule on the surface of brain cells that binds to opioids and is centrally involved in pleasure, pain, addition, depression, psychosis, and related conditions.
  
  
• New laser technique opens doors for drug discovery
  March 14, 2011
  A new laser technique has demonstrated it can measure the interactions between proteins tangled in a cell’s membrane and a variety of other biological molecules.
  
  
• Experiment reaches biology milestone with hard X-ray laser
  February 3, 2011
  Arizona State University builds protein beam injector; contributes nanocrystals.
  
  
• Scientists Develop Breakthrough Method for Finding Protein Shapes
  February 3, 2011
  An international team of researchers, including Dr. Petra Fromme of the Common Fund’s Structural Biology program, has reported a novel method for determining protein structure that overcomes many of the technical difficulties associated with previous methods.
  
  
• Researcher Discovers Shape of Proteins Important in Neurological Disorders
  October 7, 2010
  Dr. Raymond Stevens and colleagues have discovered the shape of the dopamine D3R receptor, a protein implicated in schizophrenia, Parkinson’s disease, and drug addiction.
  
  
• Researcher Discovers Shape of Proteins Important in HIV and Cancer
  October 7, 2010
  Dr. Raymond Stevens and colleagues have uncovered the structure of CXCR4, a protein important for HIV infection and cancer metastasis.
  
  
• Scripps Research Scientists Reveal First Structure of a Class of Proteins that Sniff Out Signals Guiding Blood Cell Movement
  October 4, 2010
  Researchers have determined the structure of a protein that helps guide blood-forming stem cells, or hematopoetic stem cells.
  
  
• Tiny Device Helps View Protein Structure
  June 17, 2010
  Researchers in the Common Fund's Structural Biology Research program have engineered a tiny new device to optimize the conditions needed for proteins to form crystals so their function can be studied in cells.
  
  
• Scripps Research Scientists Find Structure of a Protein that Makes Cancer Cells Resistant to Chemotherapy
  March 25, 2009
  A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells.

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