| Induced Pluripotent Stem Cells and the NIH Intramural Research Program Wilson Hall, Building 1 NIH Main Campus Bethesda, MD January 15, 2010 |
| 9:30 – 9:45am |
Welcome and Opening Remarks
Francis S. Collins, MD, PhD, Director, NIH
Michael M. Gottesman, M.D., Deputy Director for Intramural Research, NIH
|
| 9:45 – 11:05am |
Session 1: Generation and characterization of iPS cells - John O’Shea (chair)
- Shinya Yamanaka, Gladstone Institute UCSF
“Induction of Pluripotency by Defined Factors” (15 min)
- Helen Blau, Stanford
“Reprogramming towards pluripotency requires AID-dependent DNA demethylation” (15 min)
- Kristin K. Baldwin, Scripps
“What we can learn from mice derived from induced pluripotent stem cells.” (15 min)
- Ron McKay, NIH
“Characterization of hES and iPS cells”
|
| 11:05 – 11:20am |
Break - cafeteria
|
| 11:20 – 12:20pm |
Session 2: Disease Modeling, Opportunities, and Issues, Part 1
- Paul Liu (chair)
- Rene Reijo Pera, Stanford
"iPSCs and women's reproductive and somatic health"
(15 min)
- Linzhao Cheng, Johns Hopkins
“Derivation and gene targeting of patient-specific iPS cells: towards disease modeling and treatment” (15 min)
- Lorenz Studer, Memorial Sloan Kettering Cancer Center
“iPSC based disease modeling in familial dysautonomia and other rare genetic disorders” (15 min)
|
| 12:20 – 1:30pm |
Lunch and Discussion – back of cafeteria |
| 1:30 – 2:50pm |
Session 3: Disease Modeling, Opportunities, and Issues, Part 2
- Charles Dearolf (chair)
- Margret Goodell, Baylor
“Activities and Opportunities in Pluripotential Stem Cell Research in the Texas Medical Center” (15 min)
- David Scadden, Harvard
TBA (15 min)
- James Ellis, Hospital for Sick Children, Toronto
“Pluripotency reporters and disease models”. (15 min)
- Raj Puri, FDA
"Scientific and Regulatory Perspectives on iPS Cell Derived Cellular Products" (15 min)
|
| 2:50 – 3:00pm |
Break – coffee provided |
| 3:00 – 4:30pm |
Session 4: Informal discussion about possible roles for the Intramural Research Program |
| 4:30pm |
Closing Remarks, Francis Collins and Michael Gottesman |
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