2012 NIH CRM Pilot Projects for Clinical Applications |
| PI Name |
Institution Name |
Title |
BONNEMANN, CARSTEN |
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
Using iPSC to model the neurological phenotype of alpha-dystroglycanopathie |
LIANG, T. JAKE |
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
iPSC-derived Human Hepatocytes: A Model for Treatment of Liver Disease |
LIU, PAUL P. |
NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
Towards cell therapy for FPD/AML with patient-specific iPS cells |
MILLER, SHELDON |
NATIONAL EYE INSTITUTE |
Constructing Functional iPSC-derived RPE Tissue for Cell-based Therapy |
RESTIFO, NICHOLAS |
NATIONAL CANCER INSTITUTE |
Regenerative medicine using lineage reprogramming of tumor-specific T cells |
USDIN, KAREN |
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
Making neurons from FX iPSCs to study disease pathology and to screen for drugs |
| 2011 NIH CRM Pilot Projects for Clinical Applications |
| PI Name |
Institution Name |
Title |
| BOEHM, MANFRED |
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE |
Reprogramming and lineage differentiations of IPS cells from HIES patients
|
| DENG, CHUXIA |
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
Targeted correction of human and mouse iPS cells for liver diseases
|
| DUNBAR, CYNTHIA |
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE |
Preclinical Development of reprogrammed cells utilizing the rhesus macaque |
| FISCHBECK, KENNETH |
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
An iPS cell system for the study of motor neuron disease |
| JETTEN, ANTON |
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES |
Induction of pancreatic beta cell development in iPS cells by GLIS3 |
| MALECH, HARRY |
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES |
Gene Repaired Autologous iPSC to treat Chronic Granulomatous Disease
|
| MILLER, SHELDON |
NATIONAL EYE INSTITUTE |
Mechanisms of AMD Initiation Using iPS Cell-Derived RPE
|
| PARK, JOHN |
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
Stimulation of anti-glioma immune responses by iPS cell-derived microglia |
| SARTORELLI, VITTORIO |
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES |
Role of Epigenetic Regulators in iPS and SCNT-derived ESCs
|
| SIDRANSKY, ELLEN |
NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
iPSc to study and treat Gaucher disease and associated parkinsonism |
| SWAROOP, ANAND |
NATIONAL EYE INSTITUTE |
Therapies for early onset retinal degeneration using iPS cell technology |
| WESTPHAL, HEINER |
NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT |
iPS cells for the analysis and treatment of SLOS, a rare childhood disorder |
| YOUNG, NEAL |
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE |
Induced pluripotent stem cells to model telomere regulation and cell therapy |
| 2010 NIH CRM Pilot Projects for Clinical Applications |
| PI Name |
Institution Name |
Title |
| AUSTIN, CHRISTOPHER |
NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
Development of iPS Cell-Based Disease Model of Niemann-Pick Disease Type C |
| BOHELER, KENNETH |
NATIONAL INSTITUTE OF AGING |
Isolation of "homogeneous" human iPS cell populations |
| FINKEL, TOREN |
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE |
Cardiovascular Applications of iPS Cells |
| FISCHBECK, KENNETH |
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE |
iPS cells for mechanistic and therapeutic studies of motor neuron disease |
| KELLEY, MATTHEW |
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS |
Induction of hair cell regeneration using induced pluripotent stem cells |
| KUEHN, MICHAEL |
NATIONAL CANCER INSTITUTE |
Assessing the Smads2/3 dependent epigenetic landscape in iPSC |
| LIU, PAUL P |
NATIONAL HUMAN GENOME RESEARCH INSTITUTE |
Development of a Reference Set of Comprehensively Characterized iPS cell li |
| MILLER, SHELDON |
NATIONAL EYE INSTITUTE |
Restoring Vision: Criteria for iPS Cell Derived Retinal Pigment Epithelia |
| RESTIFO, NICHOLAS |
NATIONAL CANCER INSTITUTE |
Reprogramming tumor-specific T cells using iPS for cancer immunotherapy |
| ROBEY, PAMELA |
NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH |
Differentiation of human iPSCs into bone and cartilage |
| WEINBERGER, DANIEL |
NATIONAL INSTITUTE OF MENTAL HEALTH |
Validation of human GABA inter-neurons derived from iPS cells |
