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Metabolomics (574)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Systems Analysis of the Complement-Induced Priming Phase of Liver Regeneration.Min, Jun S; DeAngelis, Robert A; Reis, Edimara S; Gupta, Shakti; Maurya, Mano R; Evans, Charles; Das, Arun; Burant, Charles; Lambris, John D; Subramaniam, ShankarJournal of immunology (Baltimore, Md. : 1950).2016 Sep 15;27511733
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.Sousa, Cristovão M; Biancur, Douglas E; Wang, Xiaoxu; Halbrook, Christopher J; Sherman, Mara H; Zhang, Li; Kremer, Daniel; Hwang, Rosa F; Witkiewicz, Agnes K; Ying, Haoqiang; Asara, John M; Evans, Ronald M; Cantley, Lewis C; Lyssiotis, Costas A; Kimmelman, Alec CNature.2016 Aug 25;27509858
Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).Lane, Andrew N; Higashi, Richard M; Fan, Teresa W-MMetabolomics : Official journal of the Metabolomic Society.2016 Jul;27489532
Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.Padanad, Mahesh S; Konstantinidou, Georgia; Venkateswaran, Niranjan; Melegari, Margherita; Rindhe, Smita; Mitsche, Matthew; Yang, Chendong; Batten, Kimberly; Huffman, Kenneth E; Liu, Jingwen; Tang, Ximing; Rodriguez-Canales, Jaime; Kalhor, Neda; Shay, Jerry W; Minna, John D; McDonald, Jeffrey; Wistuba, Ignacio I; DeBerardinis, Ralph J; Scaglioni, Pier PaoloCell reports.2016 Aug 9;27477280
Reversal of chemoresistance in ovarian cancer by co-delivery of a P-glycoprotein inhibitor and paclitaxel in a liposomal platform.Zhang, Yilin; Sriraman, Shravan Kumar; Kenny, Hilary A; Luther, Ed; Torchilin, Vladimir; Lengyel, ErnstMolecular cancer therapeutics.2016 Jul 27;27466355
Preterm neonatal urinary renal developmental and acute kidney injury metabolomic profiling: an exploratory study.Mercier, Kelly; McRitchie, Susan; Pathmasiri, Wimal; Novokhatny, Andrew; Koralkar, Rajesh; Askenazi, David; Brophy, Patrick D; Sumner, SusanPediatric nephrology (Berlin, Germany).2016 Jul 19;27435284
Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data.Barnes, Stephen; Benton, H Paul; Casazza, Krista; Cooper, Sara J; Cui, Xiangqin; Du, Xiuxia; Engler, Jeffrey; Kabarowski, Janusz H; Li, Shuzhao; Pathmasiri, Wimal; Prasain, Jeevan K; Renfrow, Matthew B; Tiwari, Hemant KJournal of mass spectrometry : JMS.2016 Jul;27434804
Perinatal triphenyl phosphate exposure accelerates type 2 diabetes onset and increases adipose accumulation in UCD-type 2 diabetes mellitus rats.Green, Adrian J; Graham, James L; Gonzalez, Eduardo A; La Frano, Michael R; Petropoulou, Syrago-Styliani E; Park, June-Soo; Newman, John W; Stanhope, Kimber L; Havel, Peter J; La Merrill, Michele AReproductive toxicology (Elmsford, N.Y.).2016 Jul 12;27421578
A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.Shahin, Mohamed H; Gong, Yan; McDonough, Caitrin W; Rotroff, Daniel M; Beitelshees, Amber L; Garrett, Timothy J; Gums, John G; Motsinger-Reif, Alison; Chapman, Arlene B; Turner, Stephen T; Boerwinkle, Eric; Frye, Reginald F; Fiehn, Oliver; Cooper-DeHoff, Rhonda M; Kaddurah-Daouk, Rima; Johnson, Julie AHypertension.2016 Jul 5;27381900
Evaluation of coverage, retention patterns, and selectivity of seven liquid chromatographic methods for metabolomics.Wernisch, Stefanie; Pennathur, SubramaniamAnalytical and bioanalytical chemistry.2016 Jul 1;27370688
Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding.Xu, Jiawen; Morisseau, Christophe; Yang, Jun; Lee, Kin Sing Stephen; Kamita, Shizuo G; Hammock, Bruce DInsect biochemistry and molecular biology.2016 Jun 28;27369469
Experimental pain phenotyping in community-dwelling individuals with knee osteoarthritis.Cardoso, Josue S; Riley 3rd, Joseph L; Glover, Toni; Sibille, Kimberly T; Bartley, Emily J; Goodin, Burel R; Bulls, Hailey W; Herbert, Matthew; Addison, Adriana S; Staud, Roland; Redden, David T; Bradley, Laurence A; Fillingim, Roger B; Cruz-Almeida, YeniselPain.2016 Sep;27340911
Association between plasma endocannabinoids and appetite in hemodialysis patients: A pilot study.Friedman, Allon N; Kim, Jeffrey; Kaiser, Shaun; Pedersen, Theresa L; Newman, John W; Watkins, Bruce ANutrition research (New York, N.Y.).2016 Jul;27333956
Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion.Faber, Franziska; Tran, Lisa; Byndloss, Mariana X; Lopez, Christopher A; Velazquez, Eric M; Kerrinnes, Tobias; Nuccio, Sean-Paul; Wangdi, Tamding; Fiehn, Oliver; Tsolis, Renée M; Bäumler, Andreas JNature.2016 Jun 30;27309805
NMR-based metabolomics reveals urinary metabolome modifications in female Sprague-Dawley rats by cranberry procyanidins.Liu, Haiyan; Tayyari, Fariba; Edison, Arthur S; Su, Zhihua; Gu, LiweiThe Journal of nutritional biochemistry.2016 Aug;27309592
Maternal Early Pregnancy Serum Metabolomics Profile and Abnormal Vaginal Bleeding as Predictors of Placental Abruption: A Prospective Study.Gelaye, Bizu; Sumner, Susan J; McRitchie, Susan; Carlson, James E; Ananth, Cande V; Enquobahrie, Daniel A; Qiu, Chunfang; Sorensen, Tanya K; Williams, Michelle APloS one.2016;27300725
The Importance of the Biological Impact of Exposure to the Concept of the Exposome.Dennis, Kristine K; Auerbach, Scott S; Balshaw, David M; Cui, Yuxia; Fallin, Margaret Daniele; Smith, Martyn T; Spira, Avrum; Sumner, Susan; Miller, Gary WEnvironmental health perspectives.2016 Jun 3;27258438
Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes.Leamy, Alexandra K; Hasenour, Clinton M; Egnatchik, Robert A; Trenary, Irina A; Yao, Cong-Hui; Patti, Gary J; Shiota, Masakazu; Young, Jamey DBiochimica et biophysica acta.2016 Sep;27249207
Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation.Noecker, Cecilia; Eng, Alexander; Srinivasan, Sujatha; Theriot, Casey M; Young, Vincent B; Jansson, Janet K; Fredricks, David N; Borenstein, ElhananmSystems.2016 Jan-Feb;27239563
Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large IntesTheriot, Casey M; Bowman, Alison A; Young, Vincent BmSphere.2016 Jan-Feb;27239562
Microfluidics meets metabolomics to reveal the impact of Campylobacter jejuni infection on biochemical pathways.Mortensen, Ninell P; Mercier, Kelly A; McRitchie, Susan; Cavallo, Tammy B; Pathmasiri, Wimal; Stewart, Delisha; Sumner, Susan JBiomedical microdevices.2016 Jun;27231016
Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts.Hankin, Joseph A; Barkley, Robert M; Zemski-Berry, Karin; Deng, Yiming; Murphy, Robert CAnalytical chemistry.2016 Jun 21;27213895
Purinergic dysregulation in pulmonary hypertension.Visovatti, Scott H; Hyman, Matthew C; Goonewardena, Sascha N; Anyanwu, Anuli C; Kanthi, Yogendra; Robichaud, Patrick; Wang, Jintao; Petrovic-Djergovic, Danica; Rattan, Rahul; Burant, Charles F; Pinsky, David JAmerican journal of physiology. Heart and circulatory physiology.2016 Jul 1;27208163
Serum Cortisol-to-Cortisone Ratio and Blood Pressure in Severe Obesity before and after Weight Loss.Byrd, James B; Rothberg, Amy E; Chomic, Robert; Burant, Charles F; Brook, Robert D; Auchus, Richard JCardiorenal medicine.2015 Dec;27194991
An obligatory role for neurotensin in high-fat-diet-induced obesity.Li, Jing; Song, Jun; Zaytseva, Yekaterina Y; Liu, Yajuan; Rychahou, Piotr; Jiang, Kai; Starr, Marlene E; Kim, Ji Tae; Harris, Jennifer W; Yiannikouris, Frederique B; Katz, Wendy S; Nilsson, Peter M; Orho-Melander, Marju; Chen, Jing; Zhu, Haining; Fahrenholz, Timothy; Higashi, Richard M; Gao, Tianyan; Morris, Andrew J; Cassis, Lisa A; Fan, Teresa W-M; Weiss, Heidi L; Dobner, Paul R; Melander, Olle; Jia, Jianhang; Evers, B MarkNature2016 May 1927193687
Greazy: Open-Source Software for Automated Phospholipid Tandem Mass Spectrometry Identification.Kochen, Michael A; Chambers, Matthew C; Holman, Jay D; Nesvizhskii, Alexey I; Weintraub, Susan T; Belisle, John T; Islam, M Nurul; Griss, Johannes; Tabb, David LAnalytical chemistry2016 May 2427186799
Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy.Koethe, John R; Jenkins, Cathy A; Petucci, Christopher; Culver, Jeffrey; Shepherd, Bryan E; Sterling, Timothy RMedicine.2016 May;27175676
Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract.Winston, Jenessa A; Theriot, Casey MAnaerobe2016 May 727163871
Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation.Sirish, Padmini; Li, Ning; Timofeyev, Valeriy; Zhang, Xiao-Dong; Wang, Lianguo; Yang, Jun; Lee, Kin Sing Stephen; Bettaieb, Ahmed; Ma, Sin Mei; Lee, Jeong Han; Su, Demetria; Lau, Victor C; Myers, Richard E; Lieu, Deborah K; López, Javier E; Young, J Nilas; Yamoah, Ebenezer N; Haj, Fawaz; Ripplinger, Crystal M; Hammock, Bruce D; Chiamvimonvat, NipavanCirculation. Arrhythmia and electrophysiology.2016 May;27162031
Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes.Konopka, Adam R; Esponda, Raul Ruiz; Robinson, Matthew M; Johnson, Matthew L; Carter, Rickey E; Schiavon, Michele; Cobelli, Claudio; Wondisford, Fredric E; Lanza, Ian R; Nair, K SreekumaranCell reports2016 May 1727160898
Stable Isotope Resolved Metabolomics Studies in Ex Vivo TIssue Slices.Fan, Teresa W-M; Lane, Andrew N; Higashi, Richard MBio-protocol2016 Feb 527158639
Plasma sphingolipid changes with autopsy-confirmed Lewy Body or Alzheimer's pathology.Savica, Rodolfo; Murray, Melissa E; Persson, Xuan-Mai; Kantarci, Kejal; Parisi, Joseph E; Dickson, Dennis W; Petersen, Ronald C; Ferman, Tanis J; Boeve, Bradley F; Mielke, Michelle MAlzheimer's & dementia (Amsterdam, Netherlands).2016;27152320
Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.Wang, Weimin; Kryczek, Ilona; Dost�l, Lubom�r; Lin, Heng; Tan, Lijun; Zhao, Lili; Lu, Fujia; Wei, Shuang; Maj, Tomasz; Peng, Dongjun; He, Gong; Vatan, Linda; Szeliga, Wojciech; Kuick, Rork; Kotarski, Jan; Tarkowski, Rafa?; Dou, Yali; Rattan, Ramandeep; Munkarah, Adnan; Liu, J Rebecca; Zou, WeipingCell2016 May 1927133165
RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells.Wynn, Michelle L; Yates, Joel A; Evans, Charles R; Van Wassenhove, Lauren D; Wu, Zhi Fen; Bridges, Sydney; Bao, Liwei; Fournier, Chelsea; Ashrafzadeh, Sepideh; Merrins, Matthew J; Satin, Leslie S; Schnell, Santiago; Burant, Charles F; Merajver, Sofia DThe Journal of biological chemistry.2016 Jun 24;27129239
An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis.Chen, Jun; Wright, Kerry; Davis, John M; Jeraldo, Patricio; Marietta, Eric V; Murray, Joseph; Nelson, Heidi; Matteson, Eric L; Taneja, VeenaGenome medicine.2016;27102666
Lysosomal protein relocation as an adaptation mechanism to extracellular acidosis.Damaghi, Mehdi; Gillies, Robert JCell cycle (Georgetown, Tex.).2016 Jul 2;27097301
Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure.Nording, Malin L; Yang, Jun; Hoang, Laura; Zamora, Vanessa; Uyeminami, Dale; Espiritu, Imelda; Pinkerton, Kent E; Hammock, Bruce D; Luria, AyalaJournal of metabolomics2015 Apr27076918
Computational Modeling of Competitive Metabolism between ?3- and ?6-Polyunsaturated Fatty Acids in Inflammatory Macrophages.Gupta, Shakti; Kihara, Yasuyuki; Maurya, Mano R; Norris, Paul C; Dennis, Edward A; Subramaniam, ShankarThe journal of physical chemistry. B.2016 Aug 25;27063350
Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts.Yao, Cong-Hui; Fowle-Grider, Ronald; Mahieu, Nathanial G; Liu, Gao-Yuan; Chen, Ying-Jr; Wang, Rencheng; Singh, Manmilan; Potter, Gregory S; Gross, Richard W; Schaefer, Jacob; Johnson, Stephen L; Patti, Gary JCell chemical biology.2016 Apr 21;27049668
Metabolomics by Gas Chromatography-Mass Spectrometry: Combined Targeted and Untargeted Profiling.Fiehn, OliverCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]27038389
(1)H NMR Metabolomics Study of Spleen from C57BL/6 Mice Exposed to Gamma Radiation.Xiao, X; Hu, M; Liu, M; Hu, J ZMetabolomics : open access27019763
Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for Cardiolipin in Cellular Function.Sandlers, Yana; Mercier, Kelly; Pathmasiri, Wimal; Carlson, Jim; McRitchie, Susan; Sumner, Susan; Vernon, Hilary JPloS one.2016;27015085
Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study.Loeser, R F; Pathmasiri, W; Sumner, S J; McRitchie, S; Beavers, D; Saxena, P; Nicklas, B J; Jordan, J; Guermazi, A; Hunter, D J; Messier, S POsteoarthritis and cartilage / OARS, Osteoarthritis Research Society2016 Mar 2127012755
Mass spectrometry-based monitoring of millisecond protein-ligand binding dynamics using an automated microfluidic platform.Cong, Yongzheng; Katipamula, Shanta; Trader, Cameron D; Orton, Daniel J; Geng, Tao; Baker, Erin S; Kelly, Ryan TLab on a chip2016 Apr 2627009517
Darwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces.Lloyd, Mark C; Cunningham, Jessica J; Bui, Marilyn M; Gillies, Robert J; Brown, Joel S; Gatenby, Robert ACancer research.2016 Jun 1;27009166
Urinary proteomics and metabolomics studies to monitor bladder health and urological diseases.Chen, Zhaohui; Kim, JayoungBMC urology27000794
Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.Mathewson, Nathan D; Jenq, Robert; Mathew, Anna V; Koenigsknecht, Mark; Hanash, Alan; Toubai, Tomomi; Oravecz-Wilson, Katherine; Wu, Shin-Rong; Sun, Yaping; Rossi, Corinne; Fujiwara, Hideaki; Byun, Jaeman; Shono, Yusuke; Lindemans, Caroline; Calafiore, Marco; Schmidt, Thomas C; Honda, Kenya; Young, Vincent B; Pennathur, Subramaniam; van den Brink, Marcel; Reddy, PavanNature immunology.2016 May;26998764
1D-¹H-nuclear magnetic resonance metabolomics reveals age-related changes in metabolites associated with experimental venous thrombosis.Obi, Andrea T; Stringer, Kathleen A; Diaz, Jose A; Finkel, Michael A; Farris, Diana M; Yeomans, Larisa; Wakefield, Thomas; Myers Jr, Daniel DJournal of vascular surgery. Venous and lymphatic disorders.2016 Apr;26993871
Extraction, Enrichment, Solubilization, and Digestion Techniques for Membrane Proteomics.Moore, Stephanie M; Hess, Stephanie M; Jorgenson, James WJournal of proteome research.2016 Apr 1;26979493
Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress.Ren, Qian; Ma, Min; Ishima, Tamaki; Morisseau, Christophe; Yang, Jun; Wagner, Karen M; Zhang, Ji-Chun; Yang, Chun; Yao, Wei; Dong, Chao; Han, Mei; Hammock, Bruce D; Hashimoto, KenjiProceedings of the National Academy of Sciences of the United States of America.2016 Mar 29;26976569
Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells.Sondhi, Varun; Owen, Bryn M; Liu, Jiayan; Chomic, Robert; Kliewer, Steven A; Hughes, Beverly A; Arlt, Wiebke; Mangelsdorf, David J; Auchus, Richard JMolecular endocrinology (Baltimore, Md.).2016 Apr;26974035
Applications of NMR spectroscopy to systems biochemistry.Fan, Teresa W-M; Lane, Andrew NProgress in nuclear magnetic resonance spectroscopy2016 Feb26952191
Contemporary views on the genetics of anorexia nervosa.Shih, Pei-an Betty; Woodside, D BlakeEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.2016 Apr;26944296
Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates.Zhao, Yan; Wan, Debin; Yang, Jun; Hammock, Bruce D; Ortiz de Montellano, Paul RDrug metabolism and disposition: the biological fate of chemicals.2016 May;26936974
Effect of Pramlintide on Postprandial Glucose Fluxes in Type 1 Diabetes.Hinshaw, Ling; Schiavon, Michele; Dadlani, Vikash; Mallad, Ashwini; Dalla Man, Chiara; Bharucha, Adil; Basu, Rita; Geske, Jennifer R; Carter, Rickey E; Cobelli, Claudio; Basu, Ananda; Kudva, Yogish CThe Journal of clinical endocrinology and metabolism.2016 May;26930181
Emerging new strategies for successful metabolite identification in metabolomics.Bingol, Kerem; Bruschweiler-Li, Lei; Li, Dawei; Zhang, Bo; Xie, Mouzhe; Brüschweiler, RafaelBioanalysis.2016 Mar;26915807
Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer.Enriquez-Navas, Pedro M; Kam, Yoonseok; Das, Tuhin; Hassan, Sabrina; Silva, Ariosto; Foroutan, Parastou; Ruiz, Epifanio; Martinez, Gary; Minton, Susan; Gillies, Robert J; Gatenby, Robert AScience translational medicine.2016 Feb 24;26912903
Fluorescent RNA Aptamers as a Tool to Study RNA-Modifying Enzymes.Svensen, Nina; Jaffrey, Samie RCell chemical biology.2016 Mar 17;26877022
An Integrated Metabolomic and Microbiome Analysis Identified Specific Gut Microbiota Associated with Fecal Cholesterol and Coprostanol in Clostridium difficile Infection.Antharam, Vijay C; McEwen, Daniel C; Garrett, Timothy J; Dossey, Aaron T; Li, Eric C; Kozlov, Andrew N; Mesbah, Zhubene; Wang, Gary PPloS one.2016;26871580
Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure.Bahra, Sarah M; Weidemann, Benjamin J; Castro, Ana N; Walsh, John W; deLeon, Orlando; Burnett, Colin M L; Pearson, Nicole A; Murry, Daryl J; Grobe, Justin L; Kirby, John REBioMedicine.2015 Nov;26870798
Adrenal-derived 11-oxygenated 19-carbon steroids are the dominant androgens in classic 21-hydroxylase deficiency.Turcu, Adina F; Nanba, Aya T; Chomic, Robert; Upadhyay, Sunil K; Giordano, Thomas J; Shields, James J; Merke, Deborah P; Rainey, William E; Auchus, Richard JEuropean journal of endocrinology / European Federation of Endocrine Societies.2016 May;26865584
White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.Klosinski, Lauren P; Yao, Jia; Yin, Fei; Fonteh, Alfred N; Harrington, Michael G; Christensen, Trace A; Trushina, Eugenia; Brinton, Roberta DiazEBioMedicine.2015 Dec;26844268
Microbial metabolomics in open microscale platforms.Barkal, Layla J; Theberge, Ashleigh B; Guo, Chun-Jun; Spraker, Joe; Rappert, Lucas; Berthier, Jean; Brakke, Kenneth A; Wang, Clay C C; Beebe, David J; Keller, Nancy P; Berthier, ErwinNature communications.2016;26842393
Bar Coding MS(2) Spectra for Metabolite Identification.Spalding, Jonathan L; Cho, Kevin; Mahieu, Nathaniel G; Nikolskiy, Igor; Llufrio, Elizabeth M; Johnson, Stephen L; Patti, Gary JAnalytical chemistry2016 Mar 126837423
Surprising impact of remote groups on the folding--unfolding and dimer-chain equilibria of bifunctional H-bonding unimers.Liu, Rui; Cheng, Shuang; Baker, Erin S; Smith, Richard D; Zeng, Xiao Cheng; Gong, BingChemical communications (Cambridge, England).2016 Mar 7;26830456
Isotopic Ratio Outlier Analysis of the S. cerevisiae Metabolome Using Accurate Mass Gas Chromatography/Time-of-Flight Mass Spectrometry: A New Method for Discovery.Qiu, Yunping; Moir, Robyn; Willis, Ian; Beecher, Chris; Tsai, Yu-Hsuan; Garrett, Timothy J; Yost, Richard A; Kurland, Irwin JAnalytical chemistry.2016 Mar 1;26820234
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity.Patterson, Rainey E; Kalavalapalli, Srilaxmi; Williams, Caroline M; Nautiyal, Manisha; Mathew, Justin T; Martinez, Janie; Reinhard, Mary K; McDougall, Danielle J; Rocca, James R; Yost, Richard A; Cusi, Kenneth; Garrett, Timothy J; Sunny, Nishanth EAmerican journal of physiology. Endocrinology and metabolism.2016 Apr 1;26814015
Impact of Long-Term Poor and Good Glycemic Control on Metabolomics Alterations in Type 1 Diabetic People.Dutta, Tumpa; Kudva, Yogish C; Persson, Xuan-Mai T; Schenck, Louis A; Ford, G Charles; Singh, Ravinder J; Carter, Rickey; Nair, K SreekumaranThe Journal of clinical endocrinology and metabolism2016 Mar26796761
Metabolic Profiling of Right Ventricular-Pulmonary Vascular Function Reveals Circulating Biomarkers of Pulmonary Hypertension.Lewis, Gregory D; Ngo, Debby; Hemnes, Anna R; Farrell, Laurie; Domos, Carly; Pappagianopoulos, Paul P; Dhakal, Bishnu P; Souza, Amanda; Shi, Xu; Pugh, Meredith E; Beloiartsev, Arkadi; Sinha, Sumita; Clish, Clary B; Gerszten, Robert EJournal of the American College of Cardiology.2016 Jan 19;26791065
Direct Evidence of Acetaminophen Interference with Subcutaneous Glucose Sensing in Humans: A Pilot Study.Basu, Ananda; Veettil, Sona; Dyer, Roy; Peyser, Thomas; Basu, RitaDiabetes technology & therapeutics.2016 Feb;26784129
Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity.Peters, Pamela N; Schryver, Elizabeth M; Lengyel, Ernst; Kenny, HilaryJournal of visualized experiments : JoVE.2015;26780294
A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation.Viader, Andreu; Ogasawara, Daisuke; Joslyn, Christopher M; Sanchez-Alavez, Manuel; Mori, Simone; Nguyen, William; Conti, Bruno; Cravatt, Benjamin FeLife.2016;26779719
Metabolomic Profiling of Arginine Metabolome Links Altered Methylation to Chronic Kidney Disease Accelerated Atherosclerosis.Mathew, Anna V; Zeng, Lixia; Byun, Jaeman; Pennathur, SubramaniamJournal of proteomics & bioinformatics.2015 Oct;26778898
Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease.Sas, Kelli M; Nair, Viji; Byun, Jaeman; Kayampilly, Pradeep; Zhang, Hongyu; Saha, Jharna; Brosius 3rd, Frank C; Kretzler, Matthias; Pennathur, SubramaniamJournal of proteomics & bioinformatics.2015 Oct;26778897
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine platelets.Rowley, Jesse W; Chappaz, Stéphane; Corduan, Aurélie; Chong, Mark M W; Campbell, Robert; Khoury, Amanda; Manne, Bhanu Kanth; Wurtzel, Jeremy G T; Michael, James V; Goldfinger, Lawrence E; Mumaw, Michele M; Nieman, Marvin T; Kile, Benjamin T; Provost, Patrick; Weyrich, Andrew SBlood.2016 Jan 14;26773046
Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery.Akintoye, Emmanuel; Wu, Jason H Y; Hou, Tao; Song, Xiaoling; Yang, Jun; Hammock, Bruce; Mozaffarian, DariushJournal of lipid research.2016 Mar;26749073
Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry.Kyle, Jennifer E; Zhang, Xing; Weitz, Karl K; Monroe, Matthew E; Ibrahim, Yehia M; Moore, Ronald J; Cha, Jeeyeon; Sun, Xiaofei; Lovelace, Erica S; Wagoner, Jessica; Polyak, Stephen J; Metz, Thomas O; Dey, Sudhansu K; Smith, Richard D; Burnum-Johnson, Kristin E; Baker, Erin SThe Analyst2016 Feb 1526734689
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.Saxena, Neetu; Maio, Nunziata; Crooks, Daniel R; Ricketts, Christopher J; Yang, Youfeng; Wei, Ming-Hui; Fan, Teresa W-M; Lane, Andrew N; Sourbier, Carole; Singh, Anamika; Killian, J Keith; Meltzer, Paul S; Vocke, Cathy D; Rouault, Tracey A; Linehan, W MarstonJournal of the National Cancer Institute.2016 Jan;26719882
Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.Pilon-Thomas, Shari; Kodumudi, Krithika N; El-Kenawi, Asmaa E; Russell, Shonagh; Weber, Amy M; Luddy, Kimberly; Damaghi, Mehdi; Wojtkowiak, Jonathan W; Mulé, James J; Ibrahim-Hashim, Arig; Gillies, Robert JCancer research.2016 Mar 15;26719539
Altered Skeletal Muscle Mitochondrial Proteome As the Basis of Disruption of Mitochondrial Function in Diabetic Mice.Zabielski, Piotr; Lanza, Ian R; Gopala, Srinivas; Holtz Heppelmann, Carrie J; Bergen 3rd, H Robert; Dasari, Surendra; Nair, K SreekumaranDiabetes2016 Mar26718503
Predictors of Whole-Body Insulin Sensitivity Across Ages and Adiposity in Adult Humans.Lalia, Antigoni Z; Dasari, Surendra; Johnson, Matthew L; Robinson, Matthew M; Konopka, Adam R; Distelmaier, Klaus; Port, John D; Glavin, Maria T; Esponda, Raul Ruiz; Nair, K Sreekumaran; Lanza, Ian RThe Journal of clinical endocrinology and metabolism2016 Feb26709968
Ultrafast Polyphenol Metabolomics of Red Wines Using MicroLC-MS/MS.Ma, Yan; Tanaka, Nobuo; Vaniya, Arpana; Kind, Tobias; Fiehn, OliverJournal of agricultural and food chemistry2016 Jan 2026698107
Antioxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota.Cai, Jingwei; Zhang, Limin; Jones, Richard A; Correll, Jared B; Hatzakis, Emmanuel; Smith, Philip B; Gonzalez, Frank J; Patterson, Andrew DJournal of proteome research2016 Feb 526696396
(13)C Tracer Studies of Metabolism in Mouse Tumor Xenografts.Lane, Andrew N; Yan, Jun; Fan, Teresa W-MBio-protocol.2015 Nov 20;26693168
A roadmap for the XCMS family of software solutions in metabolomics.Mahieu, Nathaniel G; Genenbacher, Jessica Lloyd; Patti, Gary JCurrent opinion in chemical biology.2016 Feb;87-9326673825
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction.Jiang, Changtao; Xie, Cen; Lv, Ying; Li, Jing; Krausz, Kristopher W; Shi, Jingmin; Brocker, Chad N; Desai, Dhimant; Amin, Shantu G; Bisson, William H; Liu, Yulan; Gavrilova, Oksana; Patterson, Andrew D; Gonzalez, Frank JNature communications26670557
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.Ogasawara, Daisuke; Deng, Hui; Viader, Andreu; Baggelaar, Marc P; Breman, Arjen; den Dulk, Hans; van den Nieuwendijk, Adriann M C H; Soethoudt, Marjolein; van der Wel, Tom; Zhou, Juan; Overkleeft, Herman S; Sanchez-Alavez, Manuel; Mo, Simone; Nguyen, William; Conti, Bruno; Liu, Xiaojie; Chen, Yao; Liu, Qing-Song; Cravatt, Benjamin F; van der Stelt, MarioProceedings of the National Academy of Sciences of the United States of America2016 Jan 526668358
Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane.Damaghi, Mehdi; Tafreshi, Narges K; Lloyd, Mark C; Sprung, Robert; Estrella, Veronica; Wojtkowiak, Jonathan W; Morse, David L; Koomen, John M; Bui, Marilyn M; Gatenby, Robert A; Gillies, Robert JNature communications.2015;26658462
Toward Merging Untargeted and Targeted Methods in Mass Spectrometry-Based Metabolomics and Lipidomics.Cajka, Tomas; Fiehn, OliverAnalytical chemistry2016 Jan 526637011
Chronic Zinc Deficiency Alters Chick Gut Microbiota Composition and Function.Reed, Spenser; Neuman, Hadar; Moscovich, Sharon; Glahn, Raymond P; Koren, Omry; Tako, EladNutrients.2015 Dec;26633470
Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1?-dependent manner.Kakazu, Eiji; Mauer, Amy S; Yin, Meng; Malhi, HarmeetJournal of lipid research2016 Feb26621917
Insulin:Carbohydrate Ratio--Part of the Story.Basu, Ananda; Basu, RitaDiabetes technology & therapeutics.2015 Dec;26618719
Virus encoded circulatory miRNAs for early detection of prostate cancer.Kim, Jayoung; Yun, Seok Joong; Kim, Wun-JaeBMC urology.2015;11626612689
Metabolite Signatures in Hydrophilic Extracts of Mouse Lungs Exposed to Cigarette Smoke Revealed by (1)H NMR Metabolomics Investigation.Jz, Hu; X, Wang; J, Feng; Bj, Robertson; Km, Waters; Sc, Tilton; Jg, Pounds; Ra, Corley; M, Liu; M, HuMetabolomics : open access.2015 Jun;26609465
Nanoparticle-Assisted Removal of Protein in Human Serum for Metabolomics Studies.Zhang, Bo; Xie, Mouzhe; Bruschweiler-Li, Lei; Br�schweiler, RafaelAnalytical chemistry2016 Jan 526605638
Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response.Gao, Xing-Huang; Krokowski, Dawid; Guan, Bo-Jhih; Bederman, Ilya; Majumder, Mithu; Parisien, Marc; Diatchenko, Luda; Kabil, Omer; Willard, Belinda; Banerjee, Ruma; Wang, Benlian; Bebek, Gurkan; Evans, Charles R; Fox, Paul L; Gerson, Stanton L; Hoppel, Charles L; Liu, Ming; Arvan, Peter; Hatzoglou, MariaeLife.2015;26595448
Dose-Dependent Response of Personal Glucose Meters to Nicotinamide Coenzymes: Applications to Point-of-Care Diagnostics of Many Non-Glucose Targets in a Single Step.Zhang, Jingjing; Xiang, Yu; Wang, Miao; Basu, Ananda; Lu, YiAngewandte Chemie (International ed. in English).2016 Jan 11;26593219
A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis.Meng, Zhuo-Xian; Wang, Lin; Chang, Lin; Sun, Jingxia; Bao, Jiangyin; Li, Yaqiang; Chen, Y Eugene; Lin, Jiandie DCell reports.2015 Nov 24;26586440
Ion Mobility in Clinical Analysis: Current Progress and Future Perspectives.Chouinard, Christopher D; Wei, Michael S; Beekman, Christopher R; Kemperman, Robin H J; Yost, Richard AClinical chemistry2016 Jan26585928
Oxidative Modifications of Protein Tyrosyl Residues Are Increased in Plasma of Human Subjects with Interstitial Lung Disease.Pennathur, Subramaniam; Vivekanandan-Giri, Anuradha; Locy, Morgan L; Kulkarni, Tejaswini; Zhi, Degui; Zeng, Lixia; Byun, Jaeman; de Andrade, Joao A; Thannickal, Victor JAmerican journal of respiratory and critical care medicine.2016 Apr 15;26575972
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.Sperber, Henrik; Mathieu, Julie; Wang, Yuliang; Ferreccio, Amy; Hesson, Jennifer; Xu, Zhuojin; Fischer, Karin A; Devi, Arikketh; Detraux, Damien; Gu, Haiwei; Battle, Stephanie L; Showalter, Megan; Valensisi, Cristina; Bielas, Jason H; Ericson, Nolan G; Margaretha, Lilyana; Robitaille, Aaron M; Margineantu, Daciana; Fiehn, Oliver; Hockenbery, David; Blau, C Anthony; Raftery, Daniel; Margolin, Adam A; Hawkins, R David; Moon, Randall T; Ware, Carol B; Ruohola-Baker, HanneleNature cell biology2015 Dec26571212
Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis.Demehri, Farokh R; Frykman, Philip K; Cheng, Zhi; Ruan, Chunhai; Wester, Tomas; Nordenskj�ld, Agneta; Kawaguchi, Akemi; Hui, Thomas T; Granstr�m, Anna L; Funari, Vince; Teitelbaum, Daniel H; HAEC Collaborative Research GroupJournal of pediatric surgery2016 Jan26561246
Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity.Ma, Siming; Lee, Sang-Goo; Kim, Eun Bae; Park, Thomas J; Seluanov, Andrei; Gorbunova, Vera; Buffenstein, Rochelle; Seravalli, Javier; Gladyshev, Vadim NCell reports.2015 Nov 17;1319-2626549444
Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.Singh, Vishal; Chassaing, Benoit; Zhang, Limin; San Yeoh, Beng; Xiao, Xia; Kumar, Manish; Baker, Mark T; Cai, Jingwei; Walker, Rachel; Borkowski, Kamil; Harvatine, Kevin J; Singh, Nagendra; Shearer, Gregory C; Ntambi, James M; Joe, Bina; Patterson, Andrew D; Gewirtz, Andrew T; Vijay-Kumar, MatamCell metabolism2015 Dec 126525535
Altered Metabolic Profile With Sodium-Restricted Dietary Approaches to Stop Hypertension Diet in Hypertensive Heart Failure With Preserved Ejection Fraction.Mathew, Anna V; Seymour, E Mitchell; Byun, Jaeman; Pennathur, Subramaniam; Hummel, Scott LJournal of cardiac failure2015 Dec26497755
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.Bowtell, David D; Böhm, Steffen; Ahmed, Ahmed A; Aspuria, Paul-Joseph; Bast Jr, Robert C; Beral, Valerie; Berek, Jonathan S; Birrer, Michael J; Blagden, Sarah; Bookman, Michael A; Brenton, James D; Chiappinelli, Katherine B; Martins, Filipe Correia; Coukos, George; Drapkin, Ronny; Edmondson, Richard; Fotopoulou, Christina; Gabra, Hani; Galon, Jérôme; Gourley, Charlie; Heong, Valerie; Huntsman, David G; Iwanicki, Marcin; Karlan, Beth Y; Kaye, Allyson; Lengyel, Ernst; Levine, Douglas A; Lu, Karen H; McNeish, Iain A; Menon, Usha; Narod, Steven A; Nelson, Brad H; Nephew, Kenneth P; Pharoah, Paul; Powell Jr, Daniel J; Ramos, Pilar; Romero, Iris L; Scott, Clare L; Sood, Anil K; Stronach, Euan A; Balkwill, Frances RNature reviews. Cancer.2015 Nov;26493647
A New Horizon of DNP technology: Application to In-vivo (13)C Magnetic Resonance Spectroscopy and Imaging.Dutta, Prasanta; Martinez, Gary V; Gillies, Robert JBiophysical reviews.2013 Sep 1;26491489
Interactions Between the Gastrointestinal Microbiome and Clostridium difficile.Theriot, Casey M; Young, Vincent BAnnual review of microbiology.2015;445-6126488281
Neuropeptidomics Mass Spectrometry Reveals Signaling Networks Generated by Distinct Protease Pathways in Human Systems.Hook, Vivian; Bandeira, NunoJournal of the American Society for Mass Spectrometry.2015 Dec;26483184
Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools.Sud M1, Fahy E1, Cotter D1, Azam K1, Vadivelu I1, Burant C2, Edison A3, Fiehn O4, Higashi R5, Nair KS6, Sumner S7, Subramaniam S8.Nucleic Acids Research2015 Oct 1326467476
Dynamic m(6)A mRNA methylation directs translational control of heat shock response.Zhou, Jun; Wan, Ji; Gao, Xiangwei; Zhang, Xingqian; Jaffrey, Samie R; Qian, Shu-BingNature.2015 Oct 22;26458103
Dectin-1 Activation by a Natural Product ?-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype.Liu, Min; Luo, Fengling; Ding, Chuanlin; Albeituni, Sabrin; Hu, Xiaoling; Ma, Yunfeng; Cai, Yihua; McNally, Lacey; Sanders, Mary Ann; Jain, Dharamvir; Kloecker, Goetz; Bousamra 2nd, Michael; Zhang, Huang-ge; Higashi, Richard M; Lane, Andrew N; Fan, Teresa W-M; Yan, JunJournal of immunology (Baltimore, Md. : 1950)2015 Nov 1526453753
The balance of powers: Redox regulation of fibrogenic pathways in kidney injury.Okamura, Daryl M; Pennathur, SubramaniamRedox biology.2015 Dec;495-50426448394
Use of the second-generation antipsychotic, risperidone, and secondary weight gain are associated with an altered gut microbiota in children.Bahr, S M; Tyler, B C; Wooldridge, N; Butcher, B D; Burns, T L; Teesch, L M; Oltman, C L; Azcarate-Peril, M A; Kirby, J R; Calarge, C ATranslational psychiatry.2015;26440540
AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow.Saito, Yusuke; Chapple, Richard H; Lin, Angelique; Kitano, Ayumi; Nakada, DaisukeCell stem cell.2015 Nov 5;585-9626440282
Enhanced Pain Sensitivity Among Individuals With Symptomatic Knee Osteoarthritis: Potential Sex Differences in Central Sensitization.Bartley, Emily J; King, Christopher D; Sibille, Kimberly T; Cruz-Almeida, Yenisel; Riley 3rd, Joseph L; Glover, Toni L; Goodin, Burel R; Sotolongo, Adriana S; Herbert, Matthew S; Bulls, Hailey W; Staud, Roland; Fessler, Barri J; Redden, David T; Bradley, Laurence A; Fillingim, Roger BArthritis care & research.2016 Apr;26434740
Warpgroup: increased precision of metabolomic data processing by consensus integration bound analysis.Mahieu, Nathaniel G; Spalding, Jonathan L; Patti, Gary JBioinformatics (Oxford, England)2016 Jan 1526424859
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.Gooding, Jessica R; Jensen, Mette V; Dai, Xiaoqing; Wenner, Brett R; Lu, Danhong; Arumugam, Ramamani; Ferdaoussi, Mourad; MacDonald, Patrick E; Newgard, Christopher BCell reports.2015 Oct 6;157-6726411681
Liquid Chromatography-Mass Spectrometry Metabolic and Lipidomic Sample Preparation Workflow for Suspension-Cultured Mammalian Cells using Jurkat T lymphocyte Cells.Ulmer, Candice Z; Yost, Richard A; Chen, Jing; Mathews, Clayton E; Garrett, Timothy JJournal of proteomics & bioinformatics.2015 Jun;126-13226401069
Vitamin D status and pain sensitization in knee osteoarthritis: a critical review of the literature.Glover, Toni L; Horgas, Ann L; Fillingim, Roger B; Goodin, Burel RPain management.2015;26399462
Potential serum biomarkers from a metabolomics study of autism.Wang, Han; Liang, Shuang; Wang, Maoqing; Gao, Jingquan; Sun, Caihong; Wang, Jia; Xia, Wei; Wu, Shiying; Sumner, Susan J; Zhang, Fengyu; Sun, Changhao; Wu, LijieJournal of psychiatry & neuroscience : JPN.2016 Jan;26395811
The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation.Kilroy, Gail; Carter, Lauren E; Newman, Susan; Burk, David H; Manuel, Justin; Möller, Andreas; Bowtell, David D; Mynatt, Randall L; Ghosh, Sujoy; Floyd, Z ElizabethObesity (Silver Spring, Md.).2015 Sep 18;26380945
An overview of methods using (13)C for improved compound identification in metabolomics and natural products.Clendinen, Chaevien S; Stupp, Gregory S; Ajredini, Ramadan; Lee-McMullen, Brittany; Beecher, Chris; Edison, Arthur SFrontiers in plant science.2015;26379677
Decline of Phosphotransfer and Substrate Supply Metabolic Circuits Hinders ATP Cycling in Aging Myocardium.Nemutlu, Emirhan; Gupta, Anu; Zhang, Song; Viqar, Maria; Holmuhamedov, Ekhson; Terzic, Andre; Jahangir, Arshad; Dzeja, PetrasPloS one.2015;e013655626378442
Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition.Tarrado-Castellarnau, Míriam; Cortés, Roldán; Zanuy, Miriam; Tarragó-Celada, Josep; Polat, Ibrahim H; Hill, Richard; Fan, Teresa W M; Link, Wolfgang; Cascante, MartaPharmacological research.2015 Dec;26375988
Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.Guo, Yanhong; Fan, Yanbo; Zhang, Jifeng; Lomberk, Gwen A; Zhou, Zhou; Sun, Lijie; Mathison, Angela J; Garcia-Barrio, Minerva T; Zhang, Ji; Zeng, Lixia; Li, Lei; Pennathur, Subramaniam; Willer, Cristen J; Rader, Daniel J; Urrutia, Raul; Chen, Y EugeneThe Journal of clinical investigation.2015 Oct 1;3819-3026368306
Vitamin D in Tear Fluid.Lu, Xiaowen; Elizondo, Rodolfo A; Nielsen, Rikke; Christensen, Erik I; Yang, Jun; Hammock, Bruce D; Watsky, Mitchell AInvestigative ophthalmology & visual science.2015 Sep;5880-726348637
Comparison of blood plasma sample preparation methods for combined LC-MS lipidomics and metabolomics.Patterson, Rainey E; Ducrocq, Antoine J; McDougall, Danielle J; Garrett, Timothy J; Yost, Richard AJournal of chromatography. B, Analytical technologies in the biomedical and life sciences.2015 Oct 1;260-626343017
Mechanism by Which Caloric Restriction Improves Insulin Sensitivity in Sedentary Obese Adults.Johnson, Matthew L; Distelmaier, Klaus; Lanza, Ian R; Irving, Brian A; Robinson, Matthew M; Konopka, Adam R; Shulman, Gerald I; Nair, K SreekumaranDiabetes.2016 Jan;74-8426324180
Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue.Ruhaak, L Renee; Taylor, Sandra L; Stroble, Carol; Nguyen, Uyen Thao; Parker, Evan A; Song, Ting; Lebrilla, Carlito B; Rom, William N; Pass, Harvey; Kim, Kyoungmi; Kelly, Karen; Miyamoto, SuzanneJournal of proteome research.2015 Nov 6;4538-4926322380
Modeling Plasma-to-Interstitium Glucose Kinetics from Multitracer Plasma and Microdialysis Data.Schiavon, Michele; Dalla Man, Chiara; Dube, Simmi; Slama, Michael; Kudva, Yogish C; Peyser, Thomas; Basu, Ananda; Basu, Rita; Cobelli, ClaudioDiabetes technology & therapeutics.2015 Nov;26313215
Glucocorticoid Excess Increases Hepatic 11?-HSD-1 Activity in Humans: Implications in Steroid-Induced Diabetes.Dube, Simmi; Slama, Michael Q; Basu, Ananda; Rizza, Robert A; Basu, RitaThe Journal of clinical endocrinology and metabolism.2015 Nov;26308294
Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women.Hebert, Sadie L; Marquet-de Rougé, Perrine; Lanza, Ian R; McCrady-Spitzer, Shelly K; Levine, James A; Middha, Sumit; Carter, Rickey E; Klaus, Katherine A; Therneau, Terry M; Highsmith, Edward W; Nair, K SreekumaranThe journals of gerontology. Series A, Biological sciences and medical sciences.2015 Nov;1409-1726297939
Retention projection enables accurate calculation of liquid chromatographic retention times across labs and methods.Abate-Pella, Daniel; Freund, Dana M; Ma, Yan; Simón-Manso, Yamil; Hollender, Juliane; Broeckling, Corey D; Huhman, David V; Krokhin, Oleg V; Stoll, Dwight R; Hegeman, Adrian D; Kind, Tobias; Fiehn, Oliver; Schymanski, Emma L; Prenni, Jessica E; Sumner, Lloyd W; Boswell, Paul GJournal of chromatography. A.2015 Sep 18;43-5126292625
Monoacylglycerol Lipase Regulates Fever Response.Sanchez-Alavez, Manuel; Nguyen, William; Mori, Simone; Moroncini, Gianluca; Viader, Andreu; Nomura, Daniel K; Cravatt, Benjamin F; Conti, BrunoPloS one.2015;e013443726287872
Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects.Nam, H W; Karpyak, V M; Hinton, D J; Geske, J R; Ho, A M C; Prieto, M L; Biernacka, J M; Frye, M A; Weinshilboum, R M; Choi, D-STranslational psychiatry.2015;26285131
Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences.Todor, Horia; Gooding, Jessica; Ilkayeva, Olga R; Schmid, Amy KPloS one.2015;e013569326284786
Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B.Wikoff, William R; Hanash, Samir; DeFelice, Brian; Miyamoto, Suzanne; Barnett, Matt; Zhao, Yang; Goodman, Gary; Feng, Ziding; Gandara, David; Fiehn, Oliver; Taguchi, AyumuJournal of clinical oncology : official journal of the American Society of Clinical Oncology.2015 Nov 20;3880-626282655
Investigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer.Fahrmann, Johannes F; Kim, Kyoungmi; DeFelice, Brian C; Taylor, Sandra L; Gandara, David R; Yoneda, Ken Y; Cooke, David T; Fiehn, Oliver; Kelly, Karen; Miyamoto, SuzanneCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.2015 Nov;1716-2326282632
Profiling the metabolome changes caused by cranberry procyanidins in plasma of female rats using (1) H NMR and UHPLC-Q-Orbitrap-HRMS global metabolomics approaches.Liu, Haiyan; Garrett, Timothy J; Tayyari, Fariba; Gu, LiweiMolecular nutrition & food research.2015 Nov;2107-1826264887
Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis.Jeong, Pildu; Ha, Yun-Sok; Yun, Seok-Joong; Yoon, Hyung Yoon; Freeman, Michael R; Kim, Jayoung; Kim, Wun-JaeBMC urology.2015 Aug 7;8026250800
Metastatic Melanoma Induced Metabolic Changes in C57BL/6J Mouse Stomach Measured by 1H NMR Spectroscopy.Wang, X; Hu, M; Liu, M; Hu, J ZMetabolomics : open access.2014;26246958
Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity.Ma, Siming; Yim, Sun Hee; Lee, Sang-Goo; Kim, Eun Bae; Lee, Sang-Rae; Chang, Kyu-Tae; Buffenstein, Rochelle; Lewis, Kaitlyn N; Park, Thomas J; Miller, Richard A; Clish, Clary B; Gladyshev, Vadim NCell metabolism.2015 Aug 4;332-4326244935
A new method to measure muscle protein synthesis in humans by endogenously introduced d9-leucine and using blood for precursor enrichment determination.Tran, Lee; Masters, Haley; Roust, Lori R; Katsanos, Christos SPhysiological reports.2015 Aug;26243214
Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales.Evans, Simon J; Assari, Shervin; Harrington, Gloria J; Chang, Ya-Wen; Burant, Charles F; McInnis, Melvin GJournal of psychiatric research.2015 Sep;61-726228402
Dietary DHA reduces downstream endocannabinoid and inflammatory gene expression and epididymal fat mass while improving aspects of glucose use in muscle in C57BL/6J mice.Kim, J; Carlson, M E; Kuchel, G A; Newman, J W; Watkins, B AInternational journal of obesity (2005)2016 Jan26219414
Using fragmentation trees and mass spectral trees for identifying unknown compounds in metabolomics.Vaniya, Arpana; Fiehn, OliverTrends in analytical chemistry : TRAC.2015 Jun 1;52-6126213431
Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action.Viader, Andreu; Blankman, Jacqueline L; Zhong, Peng; Liu, Xiaojie; Schlosburg, Joel E; Joslyn, Christopher M; Liu, Qing-Song; Tomarchio, Aaron J; Lichtman, Aron H; Selley, Dana E; Sim-Selley, Laura J; Cravatt, Benjamin FCell reports.2015 Aug 4;798-80826212325
Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial.Dassau, Eyal; Brown, Sue A; Basu, Ananda; Pinsker, Jordan E; Kudva, Yogish C; Gondhalekar, Ravi; Patek, Steve; Lv, Dayu; Schiavon, Michele; Lee, Joon Bok; Dalla Man, Chiara; Hinshaw, Ling; Castorino, Kristin; Mallad, Ashwini; Dadlani, Vikash; McCrady-Spitzer, Shelly K; McElwee-Malloy, Molly; Wakeman, Christian A; Bevier, Wendy C; Bradley, Paige K; Kovatchev, Boris; Cobelli, Claudio; Zisser, Howard C; Doyle 3rd, Francis JThe Journal of clinical endocrinology and metabolism.2015 Oct;26204135
Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization.Mariotti, Marco; Santesmasses, Didac; Capella-Gutierrez, Salvador; Mateo, Andrea; Arnan, Carme; Johnson, Rory; D'Aniello, Salvatore; Yim, Sun Hee; Gladyshev, Vadim N; Serras, Florenci; Corominas, Montserrat; Gabaldón, Toni; Guigó, RodericGenome research.2015 Sep;26194102
Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures.Meissen, John K; Hirahatake, Kristin M; Adams, Sean H; Fiehn, OliverMetabolomics : Official journal of the Metabolomic Society.2015 Jun 1;707-72126190955
Development of a New Ion Mobility (Quadrupole) Time-of-Flight Mass Spectrometer.Ibrahim, Yehia M; Baker, Erin S; Danielson 3rd, William F; Norheim, Randolph V; Prior, David C; Anderson, Gordon A; Belov, Mikhail E; Smith, Richard DInternational journal of mass spectrometry.2015 Feb 1;655-66226185483
Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer.Litchfield, Lacey M; Mukherjee, Abir; Eckert, Mark A; Johnson, Alyssa; Mills, Kathryn A; Pan, Shawn; Shridhar, Viji; Lengyel, Ernst; Romero, Iris LOncotarget.2015 Sep 15;26172303
Sealed rotors for in situ high temperature high pressure MAS NMR.Hu, Jian Zhi; Hu, Mary Y; Zhao, Zhenchao; Xu, Suochang; Vjunov, Aleksei; Shi, Hui; Camaioni, Donald M; Peden, Charles H F; Lercher, Johannes AChemical communications (Cambridge, England).2015 Aug 18;13458-6126171928
Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease.Seekatz, Anna M; Theriot, Casey M; Molloy, Caitlyn T; Wozniak, Katherine L; Bergin, Ingrid L; Young, Vincent BInfection and immunity2015 Oct26169276
Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study.Liesenfeld, David B; Grapov, Dmitry; Fahrmann, Johannes F; Salou, Mariam; Scherer, Dominique; Toth, Reka; Habermann, Nina; Böhm, Jürgen; Schrotz-King, Petra; Gigic, Biljana; Schneider, Martin; Ulrich, Alexis; Herpel, Esther; Schirmacher, Peter; Fiehn, Oliver; Lampe, Johanna W; Ulrich, Cornelia MThe American journal of clinical nutrition.2015 Aug;433-4326156741
Two elephants in the room: new hybrid nuclear magnetic resonance and mass spectrometry approaches for metabolomics.Bingol, Kerem; Brüschweiler, RafaelCurrent opinion in clinical nutrition and metabolic care.2015 Sep;471-726154280
Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise.Seiler, Sarah E; Koves, Timothy R; Gooding, Jessica R; Wong, Kari E; Stevens, Robert D; Ilkayeva, Olga R; Wittmann, April H; DeBalsi, Karen L; Davies, Michael N; Lindeboom, Lucas; Schrauwen, Patrick; Schrauwen-Hinderling, Vera B; Muoio, Deborah MCell metabolism2015 Jul 726154055
Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments.Hinshaw, Ling; Mallad, Ashwini; Dalla Man, Chiara; Basu, Rita; Cobelli, Claudio; Carter, Rickey E; Kudva, Yogish C; Basu, AnandaAmerican journal of physiology. Endocrinology and metabolism.2015 Sep 1;26152766
Gene expression changes in subcutaneous adipose tissue due to Cushing's disease.Hochberg, Irit; Harvey, Innocence; Tran, Quynh T; Stephenson, Erin J; Barkan, Ariel L; Saltiel, Alan R; Chandler, William F; Bridges, DaveJournal of molecular endocrinology.2015 Oct;81-9426150553
Metabolomics and Natural-Products Strategies to Study Chemical Ecology in Nematodes.Edison, Arthur S; Clendinen, Chaevien S; Ajredini, Ramadan; Beecher, Chris; Ponce, Francesca V; Stupp, Gregory SIntegrative and comparative biology.2015 Sep;478-8526141866
Enhancing biological analyses with three dimensional field asymmetric ion mobility, low field drift tube ion mobility and mass spectrometry (?FAIMS/IMS-MS) separations.Zhang, Xing; Ibrahim, Yehia M; Chen, Tsung-Chi; Kyle, Jennifer E; Norheim, Randolph V; Monroe, Matthew E; Smith, Richard D; Baker, Erin SThe Analyst.2015 Sep 28;6955-6326140287
Technology Use for Problem Solving in Adolescent Type 1 Diabetes.Hinshaw, Ling; Basu, AnandaDiabetes technology & therapeutics.2015 Jul;26132765
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome.Linder, Bastian; Grozhik, Anya V; Olarerin-George, Anthony O; Meydan, Cem; Mason, Christopher E; Jaffrey, Samie RNature methods.2015 Aug;767-7226121403
Nocturnal Glucose Metabolism in Type 1 Diabetes: A Study Comparing Single Versus Dual Tracer Approaches.Mallad, Ashwini; Hinshaw, Ling; Dalla Man, Chiara; Cobelli, Claudio; Basu, Rita; Lingineni, Ravi; Carter, Rickey E; Kudva, Yogish C; Basu, AnandaDiabetes technology & therapeutics.2015 Aug;587-9526121060
Metabolomics applied to the pancreatic islet.Gooding, Jessica R; Jensen, Mette V; Newgard, Christopher BArchives of biochemistry and biophysics.2015 Jun 25;26116790
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.Mitsche, Matthew A; McDonald, Jeffrey G; Hobbs, Helen H; Cohen, Jonathan CeLife.2015 Jun 26;e0799926114596
Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function.Rajeshkumar, N V; Dutta, Prasanta; Yabuuchi, Shinichi; de Wilde, Roeland F; Martinez, Gary V; Le, Anne; Kamphorst, Jurre J; Rabinowitz, Joshua D; Jain, Sanjay K; Hidalgo, Manuel; Dang, Chi V; Gillies, Robert J; Maitra, AnirbanCancer research.2015 Aug 15;26113084
Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells.ElAzzouny, Mahmoud A; Evans, Charles R; Burant, Charles F; Kennedy, Robert TPloS one.2015;26107620
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.Gao, Lu; Rabbitt, Elizabeth H; Condon, Jennifer C; Renthal, Nora E; Johnston, John M; Mitsche, Matthew A; Chambon, Pierre; Xu, Jianming; O'Malley, Bert W; Mendelson, Carole RThe Journal of clinical investigation.2015 Jul 1;2808-2426098214
Profiles of secreted neuropeptides and catecholamines illustrate similarities and differences in response to stimulation by distinct secretagogues.Podvin, Sonia; Bundey, Richard; Toneff, Thomas; Ziegler, Michael; Hook, VivianMolecular and cellular neurosciences.2015 Sep;26092702
The macrophage phagocytic receptor CD36 promotes fibrogenic pathways on removal of apoptotic cells during chronic kidney injury.Pennathur, Subramaniam; Pasichnyk, Katie; Bahrami, Nadia M; Zeng, Lixia; Febbraio, Maria; Yamaguchi, Ikuyo; Okamura, Daryl MThe American journal of pathology.2015 Aug;26092500
Gene Expression Signature in Adipose Tissue of Acromegaly Patients.Hochberg, Irit; Tran, Quynh T; Barkan, Ariel L; Saltiel, Alan R; Chandler, William F; Bridges, DavePloS one.2015 Jun 18;e012935926087292
Use of Charged Nanoparticles in NMR-Based Metabolomics for Spectral Simplification and Improved Metabolite Identification.Zhang, Bo; Xie, Mouzhe; Bruschweiler-Li, Lei; Bingol, Kerem; Brüschweiler, RafaelAnalytical chemistry.2015 Jul 21;7211-726087125
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease.Zhang, Liang; Zhang, Song; Maezawa, Izumi; Trushin, Sergey; Minhas, Paras; Pinto, Matthew; Jin, Lee-Way; Prasain, Keshar; Nguyen, Thi D T; Yamazaki, Yu; Kanekiyo, Takahisa; Bu, Guojun; Gateno, Benjamin; Chang, Kyeong-Ok; Nath, Karl A; Nemutlu, Emirhan; Dzeja, Petras; Pang, Yuan-Ping; Hua, Duy H; Trushina, EugeniaEBioMedicine.2015 Apr 1;294-30526086035
Distribution and biomarker of carbon-14 labeled fullerene C60 ([(14) C(U)]C60 ) in pregnant and lactating rats and their offspring after maternal intravenous exposure.Snyder, Rodney W; Fennell, Timothy R; Wingard, Christopher J; Mortensen, Ninell P; Holland, Nathan A; Shannahan, Jonathan H; Pathmasiri, Wimal; Lewin, Anita H; Sumner, Susan C JJournal of applied toxicology : JAT.2015 Dec;1438-5126081520
Changes in Mineral Micronutrient Status During and After Pulmonary Exacerbation in Adults With Cystic Fibrosis.Lee, Moon Jeong; Alvarez, Jessica A; Smith, Ellen M; Killilea, David W; Chmiel, James F; Joseph, Patricia M; Grossmann, Ruth E; Gaggar, Amit; Ziegler, Thomas R; Tangpricha, Vin; Vitamin D for Enhancing the Immune System in Cystic Fibrosis InvestigatorsNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition.2015 Dec;26078287
Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease.Sunny, Nishanth E; Kalavalapalli, Srilaxmi; Bril, Fernando; Garrett, Timothy J; Nautiyal, Manisha; Mathew, Justin T; Williams, Caroline M; Cusi, KennethAmerican journal of physiology. Endocrinology and metabolism.2015 Aug 15;E311-926058864
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula.?ervenka, L; Melenovsk�, V; Huskov�, Z; Sporkov�, A; B�rgelov�, M; ?karoupkov�, P; Hwang, S H; Hammock, B D; Imig, J D; Sadowski, JPhysiological research / Academia Scientiarum Bohemoslovaca26047375
Enhancing bottom-up and top-down proteomic measurements with ion mobility separations.Baker, Erin Shammel; Burnum-Johnson, Kristin E; Ibrahim, Yehia M; Orton, Daniel J; Monroe, Matthew E; Kelly, Ryan T; Moore, Ronald J; Zhang, Xing; Théberge, Roger; Costello, Catherine E; Smith, Richard DProteomics.2015 Aug;2766-7626046661
PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.Yoh, Sunnie M; Schneider, Monika; Seifried, Janna; Soonthornvacharin, Stephen; Akleh, Rana E; Olivieri, Kevin C; De Jesus, Paul D; Ruan, Chunhai; de Castro, Elisa; Ruiz, Pedro A; Germanaud, David; des Portes, Vincent; García-Sastre, Adolfo; König, Renate; Chanda, Sumit KCell.2015 Jun 4;1293-30526046437
Infant Maturity at Birth Reveals Minor Differences in the Maternal Milk Metabolome in the First Month of Lactation.Spevacek, Ann R; Smilowitz, Jennifer T; Chin, Elizabeth L; Underwood, Mark A; German, J Bruce; Slupsky, Carolyn MThe Journal of nutrition.2015 Aug;1698-70826041675
Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice.Zhang, Limin; Hatzakis, Emmanuel; Nichols, Robert G; Hao, Ruixin; Correll, Jared; Smith, Philip B; Chiaro, Christopher R; Perdew, Gary H; Patterson, Andrew DEnvironmental science & technology.2015 Jul 7;8067-7726023891
Meta-omics uncover temporal regulation of pathways across oral microbiome genera during in vitro sugar metabolism.Edlund, Anna; Yang, Youngik; Yooseph, Shibu; Hall, Adam P; Nguyen, Don D; Dorrestein, Pieter C; Nelson, Karen E; He, Xuesong; Lux, Renate; Shi, Wenyuan; McLean, Jeffrey SThe ISME journal2015 Dec26023872
Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice.Johnson, Matthew L; Lalia, Antigoni Z; Dasari, Surendra; Pallauf, Maximilian; Fitch, Mark; Hellerstein, Marc K; Lanza, Ian RAging cell.2015 Oct;734-4326010060
A less-biased analysis of metalloproteins reveals novel zinc coordination geometries.Yao, Sen; Flight, Robert M; Rouchka, Eric C; Moseley, Hunter N BProteins.2015 Aug;1470-8726009987
Defining the metabolome: size, flux, and regulation.Zamboni, Nicola; Saghatelian, Alan; Patti, Gary JMolecular cell.2015 May 21;699-70626000853
Epidermal Fatty Acid binding protein promotes skin inflammation induced by high-fat diet.Zhang, Yuwen; Li, Qiang; Rao, Enyu; Sun, Yanwen; Grossmann, Michael E; Morris, Rebecca J; Cleary, Margot P; Li, BingImmunity.2015 May 19;953-6425992864
Hepatic insulin sensitivity in healthy and prediabetic subjects: from a dual- to a single-tracer oral minimal model.Visentin, Roberto; Dalla Man, Chiara; Basu, Rita; Basu, Ananda; Rizza, Robert A; Cobelli, ClaudioAmerican journal of physiology. Endocrinology and metabolism.2015 Jul 15;E161-725991649
Oxygen concentration controls epigenetic effects in models of familial paraganglioma.Her, Yeng F; Nelson-Holte, Molly; Maher 3rd, Louis JamesPloS one.2015;25985299
Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.O'Neill, Brian T; Lauritzen, Hans P M M; Hirshman, Michael F; Smyth, Graham; Goodyear, Laurie J; Kahn, C RonaldCell reports.2015 May 26;1220-3525981038
Biochemical association of metabolic profile and microbiome in chronic pressure ulcer wounds.Ammons, Mary Cloud B; Morrissey, Kathryn; Tripet, Brian P; Van Leuven, James T; Han, Anne; Lazarus, Gerald S; Zenilman, Jonathan M; Stewart, Philip S; James, Garth A; Copié, ValériePloS one.2015 May 15;e012673525978400
Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family.Niehaus, Thomas D; Gerdes, Svetlana; Hodge-Hanson, Kelsey; Zhukov, Aleksey; Cooper, Arthur J L; ElBadawi-Sidhu, Mona; Fiehn, Oliver; Downs, Diana M; Hanson, Andrew DBMC genomics.2015 May 15;38225975565
Utilizing magnetization transfer imaging to investigate tissue remodeling in a murine model of autosomal dominant polycystic kidney disease.Kline, Timothy L; Irazabal, Maria V; Ebrahimi, Behzad; Hopp, Katharina; Udoji, Kelly N; Warner, Joshua D; Korfiatis, Panagiotis; Mishra, Prasanna K; Macura, Slobodan I; Venkatesh, Sudhakar K; Lerman, Lilach O; Harris, Peter C; Torres, Vicente E; King, Bernard F; Erickson, Bradley JMagnetic resonance in medicine.2016 Apr;25974140
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.O-Sullivan, InSug; Zhang, Wenwei; Wasserman, David H; Liew, Chong Wee; Liu, Jonathan; Paik, Jihye; DePinho, Ronald A; Stolz, Donna Beer; Kahn, C Ronald; Schwartz, Michael W; Unterman, Terry GNature communications.2015 May 12;707925963540
MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis.Tsugawa, Hiroshi; Cajka, Tomas; Kind, Tobias; Ma, Yan; Higgins, Brendan; Ikeda, Kazutaka; Kanazawa, Mitsuhiro; VanderGheynst, Jean; Fiehn, Oliver; Arita, MasanoriNature methods.2015 Jun;523-625938372
(13)C NMR Metabolomics: INADEQUATE Network Analysis.Clendinen, Chaevien S; Pasquel, Christian; Ajredini, Ramadan; Edison, Arthur SAnalytical chemistry.2015 Jun 2;5698-70625932900
Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus.Cha, Jeeyeon; Burnum-Johnson, Kristin E; Bartos, Amanda; Li, Yingju; Baker, Erin S; Tilton, Susan C; Webb-Robertson, Bobbie-Jo M; Piehowski, Paul D; Monroe, Matthew E; Jegga, Anil G; Murata, Shigeo; Hirota, Yasushi; Dey, Sudhansu KThe Journal of biological chemistry.2015 Jun 12;15337-4925931120
Cybersecurity in Artificial Pancreas Experiments.O'Keeffe, Derek T; Maraka, Spyridoula; Basu, Ananda; Keith-Hynes, Patrick; Kudva, Yogish CDiabetes technology & therapeutics.2015 Sep;25923544
Cardiac resynchronization therapy induces adaptive metabolic transitions in the metabolomic profile of heart failure.Nemutlu, Emirhan; Zhang, Song; Xu, Yi-Zhou; Terzic, Andre; Zhong, Li; Dzeja, Petras D; Cha, Yong-MeiJournal of cardiac failure.2015 Jun;460-925911126
Exercise effects on postprandial glucose metabolism in type 1 diabetes: a triple-tracer approach.Mallad, Ashwini; Hinshaw, Ling; Schiavon, Michele; Dalla Man, Chiara; Dadlani, Vikash; Basu, Rita; Lingineni, Ravi; Cobelli, Claudio; Johnson, Matthew L; Carter, Rickey; Kudva, Yogish C; Basu, AnandaAmerican journal of physiology. Endocrinology and metabolism.2015 Jun 15;E1106-1525898950
Metabolomic Analysis of Oxidative and Glycolytic Skeletal Muscles by Matrix-Assisted Laser Desorption/IonizationMass Spectrometric Imaging (MALDI MSI).Tsai, Yu-Hsuan; Garrett, Timothy J; Carter, Christy S; Yost, Richard AJournal of the American Society for Mass Spectrometry.2015 Jun;915-2325893271
Applications of Multiple Reaction Monitoring to Clinical Glycomics.Ruhaak, L Renee; Lebrilla, Carlito BChromatographia.2015 Mar 1;335-34225892741
Kernel approaches for differential expression analysis of mass spectrometry-based metabolomics data.Zhan, Xiang; Patterson, Andrew D; Ghosh, DebashisBMC bioinformatics.2015 Mar 11;7725887233
Ion Mobility and Tandem Mass Spectrometry of Phosphatidylglycerol and Bis(monoacylglycerol)phosphate (BMP).Hankin, Joseph A; Murphy, Robert C; Barkley, Robert M; Gijón, Miguel AInternational journal of mass spectrometry.2015 Feb 15;255-26325883529
Adipose Tissue Free Fatty Acid Storage In Vivo: Effects of Insulin Versus Niacin as a Control for Suppression of Lipolysis.Ali, Asem H; Mundi, Manpreet; Koutsari, Christina; Bernlohr, David A; Jensen, Michael DDiabetes.2015 Aug;2828-3525883112
NMR/MS Translator for the Enhanced Simultaneous Analysis of Metabolomics Mixtures by NMR Spectroscopy and Mass Spectrometry: Application to Human Urine.Bingol, Kerem; Brüschweiler, RafaelJournal of proteome research.2015 Jun 5;2642-825881480
Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes.Robertson-Tessi, Mark; Gillies, Robert J; Gatenby, Robert A; Anderson, Alexander R ACancer research.2015 Apr 15;25878146
Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice.Milner, J Justin; Rebeles, Jenny; Dhungana, Suraj; Stewart, Delisha A; Sumner, Susan C J; Meyers, Matthew H; Mancuso, Peter; Beck, Melinda AJournal of immunology (Baltimore, Md. : 1950).2015 May 15;4846-5925862817
Effects of Dietary n-3 Fatty Acids on Hepatic and Peripheral Insulin Sensitivity in Insulin-Resistant Humans.Lalia, Antigoni Z; Johnson, Matthew L; Jensen, Michael D; Hames, Kazanna C; Port, John D; Lanza, Ian RDiabetes care.2015 Jul;1228-3725852206
Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia.Fahrmann, Johannes; Grapov, Dmitry; Yang, Jun; Hammock, Bruce; Fiehn, Oliver; Bell, Graeme I; Hara, ManamiAmerican journal of physiology. Endocrinology and metabolism.2015 Jun 1;E978-8925852003
Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency.Turcu, Adina F; Rege, Juilee; Chomic, Robert; Liu, Jiayan; Nishimoto, Hiromi K; Else, Tobias; Moraitis, Andreas G; Palapattu, Ganesh S; Rainey, William E; Auchus, Richard JThe Journal of clinical endocrinology and metabolism.2015 Jun;2283-9025850025
MetaMapR: pathway independent metabolomic network analysis incorporating unknowns.Grapov, Dmitry; Wanichthanarak, Kwanjeera; Fiehn, OliverBioinformatics (Oxford, England).2015 Aug 15;2757-6025847005
Melatonin prevents myeloperoxidase heme destruction and the generation of free iron mediated by self-generated hypochlorous acid.Shaeib, Faten; Khan, Sana N; Ali, Iyad; Najafi, Tohid; Maitra, Dhiman; Abdulhamid, Ibrahim; Saed, Ghassan M; Pennathur, Subramaniam; Abu-Soud, Husam MPloS one.2015 Apr 2;e012073725835505
Habitual physical activity and plasma metabolomic patterns distinguish individuals with low vs. high weight loss during controlled energy restriction.Piccolo, Brian D; Keim, Nancy L; Fiehn, Oliver; Adams, Sean H; Van Loan, Marta D; Newman, John WThe Journal of nutrition.2015 Apr;681-9025833772
Application of high-resolution mass spectrometry to measure low abundance isotope enrichment in individual muscle proteins.Hines, Kelly M; Ford, G Charles; Klaus, Katherine A; Irving, Brian A; Ford, Beverly L; Johnson, Kenneth L; Lanza, Ian R; Nair, K SreekumaranAnalytical and bioanalytical chemistry.2015 May;4045-5225832482
Evidence for a link between gut microbiota and hypertension in the Dahl rat.Mell, Blair; Jala, Venkatakrishna R; Mathew, Anna V; Byun, Jaeman; Waghulde, Harshal; Zhang, Youjie; Haribabu, Bodduluri; Vijay-Kumar, Matam; Pennathur, Subramaniam; Joe, BinaPhysiological genomics.2015 Jun;187-9725829393
Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice.Harris, Todd R; Bettaieb, Ahmed; Kodani, Sean; Dong, Hua; Myers, Richard; Chiamvimonvat, Nipavan; Haj, Fawaz G; Hammock, Bruce DToxicology and applied pharmacology.2015 Jul 15;102-1125827057
Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa.Shih, P B; Yang, J; Morisseau, C; German, J B; Zeeland, A A Scott-Van; Armando, A M; Quehenberger, O; Bergen, A W; Magistretti, P; Berrettini, W; Halmi, K A; Schork, N; Hammock, B D; Kaye, WMolecular psychiatry.2015 Mar 31;25824304
Metabolism and its sequelae in cancer evolution and therapy.Gillies, Robert J; Gatenby, Robert ACancer journal (Sudbury, Mass.).2015 Mar-Apr;25815848
Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance.Verduzco, Daniel; Lloyd, Mark; Xu, Liping; Ibrahim-Hashim, Arig; Balagurunathan, Yoganand; Gatenby, Robert A; Gillies, Robert JPloS one.2015;25811878
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.Noetzli, Leila; Lo, Richard W; Lee-Sherick, Alisa B; Callaghan, Michael; Noris, Patrizia; Savoia, Anna; Rajpurkar, Madhvi; Jones, Kenneth; Gowan, Katherine; Balduini, Carlo L; Pecci, Alessandro; Gnan, Chiara; De Rocco, Daniela; Doubek, Michael; Li, Ling; Lu, Lily; Leung, Richard; Landolt-Marticorena, Carolina; Hunger, Stephen; Heller, Paula; Gutierrez-Hartmann, Arthur; Xiayuan, Liang; Pluthero, Fred G; Rowley, Jesse W; Weyrich, Andrew S; Kahr, Walter H A; Porter, Christopher C; Di Paola, JorgeNature genetics.2015 May;535-825807284
Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin.Phelan, Vanessa V; Fang, Jinshu; Dorrestein, Pieter CJournal of the American Society for Mass Spectrometry.2015 Jun;873-725801585
Microenvironment-induced downregulation of miR-193b drives ovarian cancer metastasis.Mitra, A K; Chiang, C Y; Tiwari, P; Tomar, S; Watters, K M; Peter, M E; Lengyel, EOncogene.2015 Nov 26;25798837
Effects of acute exposure to increased plasma branched-chain amino acid concentrations on insulin-mediated plasma glucose turnover in healthy young subjects.Everman, Sarah; Mandarino, Lawrence J; Carroll, Chad C; Katsanos, Christos SPloS one.2015;25781654
Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.Zhang, Limin; Nichols, Robert G; Correll, Jared; Murray, Iain A; Tanaka, Naoki; Smith, Philip B; Hubbard, Troy D; Sebastian, Aswathy; Albert, Istvan; Hatzakis, Emmanuel; Gonzalez, Frank J; Perdew, Gary H; Patterson, Andrew DEnvironmental health perspectives.2015 Jul;679-8825768209
Developmental programming: exposure to testosterone excess disrupts steroidal and metabolic environment in pregnant sheep.Abi Salloum, B; Veiga-Lopez, A; Abbott, D H; Burant, C F; Padmanabhan, VEndocrinology.2015 Jun;2323-3725763641
Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death.Rao, Enyu; Zhang, Yuwen; Zhu, Ganqian; Hao, Jiaqing; Persson, Xuan-Mai T; Egilmez, Nejat K; Suttles, Jill; Li, BingOncotarget.2015 Apr 10;7944-5825760243
Association of UCP-3 rs1626521 with obesity and stomach functions in humans.Acosta, Andres; Camilleri, Michael; Shin, Andrea; Vazquez-Roque, Maria I; Iturrino, Johanna; Lanza, Ian R; Nair, K Sreekumaran; Burton, Duane; O'Neill, Jessica; Eckert, Deborah; Carlson, Paula; Vella, Adrian; Zinsmeister, Alan RObesity (Silver Spring, Md.).2015 Apr;898-90625755013
Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation.Overmyer, Katherine A; Evans, Charles R; Qi, Nathan R; Minogue, Catherine E; Carson, Joshua J; Chermside-Scabbo, Christopher J; Koch, Lauren G; Britton, Steven L; Pagliarini, David J; Coon, Joshua J; Burant, Charles FCell metabolism.2015 Mar 3;468-7825738461
Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet.Tanaka, Naoki; Takahashi, Shogo; Zhang, Yuan; Krausz, Kristopher W; Smith, Philip B; Patterson, Andrew D; Gonzalez, Frank JBiochimica et biophysica acta.2015 Jul;1242-5225736301
Effect of insulin sensitizer therapy on amino acids and their metabolites.Irving, Brian A; Carter, Rickey E; Soop, Mattias; Weymiller, Audrey; Syed, Husnain; Karakelides, Helen; Bhagra, Sumit; Short, Kevin R; Tatpati, Laura; Barazzoni, Rocco; Nair, K SreekumaranMetabolism: clinical and experimental.2015 Jun;720-825733201
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.Chassaing, Benoit; Koren, Omry; Goodrich, Julia K; Poole, Angela C; Srinivasan, Shanthi; Ley, Ruth E; Gewirtz, Andrew TNature.2015 Mar 5;25731162
Distribution and biomarkers of carbon-14-labeled fullerene C60 ([(14) C(U)]C60 ) in female rats and mice for up to 30 days after intravenous exposure.Sumner, Susan C J; Snyder, Rodney W; Wingard, Christopher; Mortensen, Ninell P; Holland, Nathan A; Shannahan, Jonathan H; Dhungana, Suraj; Pathmasiri, Wimal; Han, Li; Lewin, Anita H; Fennell, Timothy RJournal of applied toxicology : JAT.2015 Dec;25727383
Impact of storage conditions on metabolite profiles of sputum samples from persons with cystic fibrosis.Zhao, Jiangchao; Evans, Charles R; Carmody, Lisa A; LiPuma, John JJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.2015 Jul;468-7325725986
Disrupted sleep is associated with altered pain processing by sex and ethnicity in knee osteoarthritis.Petrov, Megan E; Goodin, Burel R; Cruz-Almeida, Yenisel; King, Chris; Glover, Toni L; Bulls, Hailey W; Herbert, Matthew; Sibille, Kimberly T; Bartley, Emily J; Fessler, Barri J; Sotolongo, Adriana; Staud, Roland; Redden, David; Fillingim, Roger B; Bradley, Laurence AThe journal of pain : official journal of the American Pain Society.2015 May;25725172
Metabolomics and diabetes: analytical and computational approaches.Sas, Kelli M; Karnovsky, Alla; Michailidis, George; Pennathur, SubramaniamDiabetes.2015 Mar;718-3225713200
Molecular pathways: trafficking of metabolic resources in the tumor microenvironment.Romero, Iris L; Mukherjee, Abir; Kenny, Hilary A; Litchfield, Lacey M; Lengyel, ErnstClinical cancer research : an official journal of the American Association for Cancer Research.2015 Feb 15;25691772
Does our gut microbiome predict cardiovascular risk? A review of the evidence from metabolomics.Griffin, Julian L; Wang, Xinzhu; Stanley, ElizabethCirculation. Cardiovascular genetics.2015 Feb;187-9125691688
Discriminating precursors of common fragments for large-scale metabolite profiling by triple quadrupole mass spectrometry.Nikolskiy, Igor; Siuzdak, Gary; Patti, Gary JBioinformatics (Oxford, England).2015 Jun 15;2017-2325691443
Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus.Xu, Jiawen; Morisseau, Christophe; Yang, Jun; Mamatha, Dadala M; Hammock, Bruce DInsect biochemistry and molecular biology.2015 Apr;41-925686802
Association of branched and aromatic amino acids levels with metabolic syndrome and impaired fasting glucose in hypertensive patients.Weng, Liming; Quinlivan, Eoin; Gong, Yan; Beitelshees, Amber L; Shahin, Mohamed H; Turner, Stephen T; Chapman, Arlene B; Gums, John G; Johnson, Julie A; Frye, Reginald F; Garrett, Timothy J; Cooper-DeHoff, Rhonda MMetabolic syndrome and related disorders.2015 Jun;25664967
Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model.Overmyer, Katherine A; Thonusin, Chanisa; Qi, Nathan R; Burant, Charles F; Evans, Charles RPloS one.2015 Feb 6;e011723225658945
Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.Wikoff, William R; Grapov, Dmitry; Fahrmann, Johannes F; DeFelice, Brian; Rom, William N; Pass, Harvey I; Kim, Kyoungmi; Nguyen, UyenThao; Taylor, Sandra L; Gandara, David R; Kelly, Karen; Fiehn, Oliver; Miyamoto, SuzanneCancer prevention research (Philadelphia, Pa.).2015 May;410-825657018
Gene expression profiling in pachyonychia congenita skin.Cao, Yu-An; Hickerson, Robyn P; Seegmiller, Brandon L; Grapov, Dmitry; Gross, Maren M; Bessette, Marc R; Phinney, Brett S; Flores, Manuel A; Speaker, Tycho J; Vermeulen, Annaleen; Bravo, Albert A; Bruckner, Anna L; Milstone, Leonard M; Schwartz, Mary E; Rice, Robert H; Kaspar, Roger LJournal of dermatological science.2015 Mar;156-6525656049
Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.Kenny, Hilary A; Lal-Nag, Madhu; White, Erin A; Shen, Min; Chiang, Chun-Yi; Mitra, Anirban K; Zhang, Yilin; Curtis, Marion; Schryver, Elizabeth M; Bettis, Sam; Jadhav, Ajit; Boxer, Matthew B; Li, Zhuyin; Ferrer, Marc; Lengyel, ErnstNature communications.2015;25653139
Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase.Lin, Fengming; Ferguson, Kyle L; Boyer, David R; Lin, Xiaoxia Nina; Marsh, E Neil GACS chemical biology.2015 Apr 17;1137-4425647642
Site-specific glycosylation of secretory immunoglobulin A from human colostrum.Huang, Jincui; Guerrero, Andres; Parker, Evan; Strum, John S; Smilowitz, Jennifer T; German, J Bruce; Lebrilla, Carlito BJournal of proteome research.2015 Mar 6;1335-4925629924
Acute and chronic plasma metabolomic and liver transcriptomic stress effects in a mouse model with features of post-traumatic stress disorder.Gautam, Aarti; D'Arpa, Peter; Donohue, Duncan E; Muhie, Seid; Chakraborty, Nabarun; Luke, Brian T; Grapov, Dmitry; Carroll, Erica E; Meyerhoff, James L; Hammamieh, Rasha; Jett, MartiPloS one.2015 Jan 28;e011709225629821
Regulation of mammalian nucleotide metabolism and biosynthesis.Lane, Andrew N; Fan, Teresa W-MNucleic acids research.2015 Feb 27;2466-8525628363
Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance.Lane, Andrew N; Arumugam, Sengodagounder; Lorkiewicz, Pawel K; Higashi, Richard M; Laulhe, Sebastien; Nantz, Michael H; Moseley, Hunter N B; Fan, Teresa W-MMagnetic resonance in chemistry : MRC.2015 May;337-4325616249
Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.Sellers, Katherine; Fox, Matthew P; Bousamra 2nd, Michael; Slone, Stephen P; Higashi, Richard M; Miller, Donald M; Wang, Yali; Yan, Jun; Yuneva, Mariia O; Deshpande, Rahul; Lane, Andrew N; Fan, Teresa W-MThe Journal of clinical investigation.2015 Feb;687-9825607840
Defects in Mitochondrial Efficiency and H2O2 Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training.Konopka, Adam R; Asante, Albert; Lanza, Ian R; Robinson, Matthew M; Johnson, Matthew L; Dalla Man, Chiara; Cobelli, Claudio; Amols, Mark H; Irving, Brian A; Nair, K SDiabetes.2015 Jun;2104-1525605809
Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis.Zhao, Hong; Chiaro, Christopher R; Zhang, Limin; Smith, Philip B; Chan, Chung Yu; Pedley, Anthony M; Pugh, Raymond J; French, Jarrod B; Patterson, Andrew D; Benkovic, Stephen JThe Journal of biological chemistry.2015 Mar 13;6705-1325605736
Impact of gestational bisphenol A on oxidative stress and free fatty acids: Human association and interspecies animal testing studies.Veiga-Lopez, Almudena; Pennathur, Subramaniam; Kannan, Kurunthachalam; Patisaul, Heather B; Dolinoy, Dana C; Zeng, Lixia; Padmanabhan, VasanthaEndocrinology.2015 Mar;911-2225603046
DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics.Tsou, Chih-Chiang; Avtonomov, Dmitry; Larsen, Brett; Tucholska, Monika; Choi, Hyungwon; Gingras, Anne-Claude; Nesvizhskii, Alexey INature methods.2015 Mar;258-64, 7 p following 26425599550
Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation.Lee, Jieun; Ellis, Jessica M; Wolfgang, Michael JCell reports.2015 Jan 13;266-7925578732
A Cross-sectional Examination of Vitamin D, Obesity, and Measures of Pain and Function in Middle-aged and Older Adults With Knee Osteoarthritis.Glover, Toni L; Goodin, Burel R; King, Christopher D; Sibille, Kimberly T; Herbert, Matthew S; Sotolongo, Adriana S; Cruz-Almeida, Yenisel; Bartley, Emily J; Bulls, Hailey W; Horgas, Ann L; Redden, David T; Riley 3rd, Joseph L; Staud, Roland; Fessler, Barri J; Bradley, Laurence A; Fillingim, Roger BThe Clinical journal of pain.2015 Dec;25569220
Aryl hydrocarbon receptor ligands in cancer: friend and foe.Murray, Iain A; Patterson, Andrew D; Perdew, Gary HNature reviews. Cancer.2014 Dec;801-1425568920
Effects of tigecycline and vancomycin administration on established Clostridium difficile infection.Theriot, Casey M; Schumacher, Cassie A; Bassis, Christine M; Seekatz, Anna M; Young, Vincent BAntimicrobial agents and chemotherapy.2015 Mar;1596-60425547352
Metformin activates AMP-activated protein kinase by promoting formation of the ??? heterotrimeric complex.Meng, Shumei; Cao, Jia; He, Qiyi; Xiong, Lishou; Chang, Evan; Radovick, Sally; Wondisford, Fredric E; He, LingThe Journal of biological chemistry.2015 Feb 6;25538235
Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract.Koenigsknecht, Mark J; Theriot, Casey M; Bergin, Ingrid L; Schumacher, Cassie A; Schloss, Patrick D; Young, Vincent BInfection and immunity.2015 Mar;934-4125534943
Evaluation of the ''steal'' phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer.Bailey, Kate M; Cornnell, Heather H; Ibrahim-Hashim, Arig; Wojtkowiak, Jonathan W; Hart, Charles P; Zhang, Xiaomeng; Leos, Rafael; Martinez, Gary V; Baker, Amanda F; Gillies, Robert JPloS one.2014;25532146
Circadian variability of insulin sensitivity: physiological input for in silico artificial pancreas.Visentin, Roberto; Dalla Man, Chiara; Kudva, Yogish C; Basu, Ananda; Cobelli, ClaudioDiabetes technology & therapeutics.2015 Jan;4201125531427
High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy.Snowden, Stuart G; Grapov, Dmitry; Settergren, Magnus; D'Alexandri, Fabio Luiz; Haeggstrom, Jesper Z; Fiehn, Oliver; Hyotylainen, Tuulia; Pedersen, Theresa L; Newman, John W; Oresic, Matej; Pernow, John; Wheelock, Craig ECirculation. Cardiovascular genetics.2014 Dec;955-6425516625
Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging.Johnson, Matthew L; Irving, Brian A; Lanza, Ian R; Vendelbo, Mikkel H; Konopka, Adam R; Robinson, Matthew M; Henderson, Gregory C; Klaus, Katherine A; Morse, Dawn M; Heppelmann, Carrie; Bergen 3rd, H Robert; Dasari, Surendra; Schimke, Jill M; Jakaitis, Daniel R; Nair, K SreekumaranThe journals of gerontology. Series A, Biological sciences and medical sciences.2014 Dec 10;25504576
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.Jiang, Changtao; Xie, Cen; Li, Fei; Zhang, Limin; Nichols, Robert G; Krausz, Kristopher W; Cai, Jingwei; Qi, Yunpeng; Fang, Zhong-Ze; Takahashi, Shogo; Tanaka, Naoki; Desai, Dhimant; Amin, Shantu G; Albert, Istvan; Patterson, Andrew D; Gonzalez, Frank JThe Journal of clinical investigation.2015 Jan;386-40225500885
Pharmacometabolomics of l-carnitine treatment response phenotypes in patients with septic shock.Puskarich, Michael A; Finkel, Michael A; Karnovsky, Alla; Jones, Alan E; Trexel, Julie; Harris, Brooke N; Stringer, Kathleen AAnnals of the American Thoracic Society.2015 Jan;46-5625496487
Autonomous metabolomics for rapid metabolite identification in global profiling.Benton, H Paul; Ivanisevic, Julijana; Mahieu, Nathaniel G; Kurczy, Michael E; Johnson, Caroline H; Franco, Lauren; Rinehart, Duane; Valentine, Elizabeth; Gowda, Harsha; Ubhi, Baljit K; Tautenhahn, Ralf; Gieschen, Andrew; Fields, Matthew W; Patti, Gary J; Siuzdak, GaryAnalytical chemistry.2015 Jan 20;884-9125496351
Cardiac steatosis potentiates angiotensin II effects in the heart.Glenn, Denis J; Cardema, Michelle C; Ni, Wei; Zhang, Yan; Yeghiazarians, Yerem; Grapov, Dmitry; Fiehn, Oliver; Gardner, David GAmerican journal of physiology. Heart and circulatory physiology.2015 Feb 15;H339-5025485904
Diet and feeding pattern affect the diurnal dynamics of the gut microbiome.Zarrinpar, Amir; Chaix, Amandine; Yooseph, Shibu; Panda, SatchidanandaCell metabolism.2014 Dec 2;1006-1725470548
Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice.Mazagova, Magdalena; Wang, Lirui; Anfora, Andrew T; Wissmueller, Max; Lesley, Scott A; Miyamoto, Yukiko; Eckmann, Lars; Dhungana, Suraj; Pathmasiri, Wimal; Sumner, Susan; Westwater, Caroline; Brenner, David A; Schnabl, BerndFASEB journal : official publication of the Federation of American Societies for Experimental Biology.2015 Mar;1043-5525466902
Metabolic network motifs can provide novel insights into evolution: The evolutionary origin of Eukaryotic organelles as a case study.Shellman, Erin R; Chen, Yu; Lin, Xiaoxia; Burant, Charles F; Schnell, SantiagoComputational biology and chemistry.2014 Sep 21;242-25025462333
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.Yang, Chendong; Ko, Bookyung; Hensley, Christopher T; Jiang, Lei; Wasti, Ajla T; Kim, Jiyeon; Sudderth, Jessica; Calvaruso, Maria Antonietta; Lumata, Lloyd; Mitsche, Matthew; Rutter, Jared; Merritt, Matthew E; DeBerardinis, Ralph JMolecular cell.2014 Nov 6;414-2425458842
Old drug, new trick: repurposing metformin for gynecologic cancers?Febbraro, Terri; Lengyel, Ernst; Romero, Iris LGynecologic oncology.2014 Dec;25455733
Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models.Lengyel, Ernst; Litchfield, Lacey M; Mitra, Anirban K; Nieman, Kristin M; Mukherjee, Abir; Zhang, Yilin; Johnson, Alyssa; Bradaric, Michael; Lee, WooSeok; Romero, Iris LAmerican journal of obstetrics and gynecology.2015 Apr;25446664
A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis.Frelin, Oceane; Huang, Lili; Hasnain, Ghulam; Jeffryes, James G; Ziemak, Michael J; Rocca, James R; Wang, Bing; Rice, Jennifer; Roje, Sanja; Yurgel, Svetlana N; Gregory 3rd, Jesse F; Edison, Arthur S; Henry, Christopher S; de Crecy-Lagard, Valerie; Hanson, Andrew DThe Biochemical journal.2015 Feb 15;137-4525431972
The need for reflective consideration of an integrative understanding of cardiovascular consequences to PVP formulated C60 exposure.Wingard, Christopher J; Holland, Nathan A; Thompson, Leslie C; Brown, Jared M; Lewin, Anita H; Sumner, Susan J; Fennell, Timothy R; Vidanapathirana, Achini KToxicological sciences : an official journal of the Society of Toxicology.2014 Oct;327-825422842
Top-down analysis of highly post-translationally modified peptides by fourier transform ion cyclotron resonance mass spectrometry.Guerrero, Andres; Lerno, Larry; Barile, Daniela; Lebrilla, Carlito BJournal of the American Society for Mass Spectrometry.2015 Mar;453-925404158
Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice.Bettaieb, Ahmed; Chahed, Samah; Tabet, George; Yang, Jun; Morisseau, Christophe; Griffey, Stephen; Hammock, Bruce D; Haj, Fawaz GPloS one.2014;e11301925402489
The use of metabolomics in population-based research.Su, L Joseph; Fiehn, Oliver; Maruvada, Padma; Moore, Steven C; O'Keefe, Stephen J; Wishart, David S; Zanetti, Krista AAdvances in nutrition (Bethesda, Md.).2014 Nov;785-825398741
(1)H NMR Metabolomics Study of Metastatic Melanoma in C57BL/6J Mouse Spleen.Wang, Xuan; Hu, Mary; Feng, Ju; Liu, Maili; Hu, Jian ZhiMetabolomics : Official journal of the Metabolomic Society.2014 Dec;1129-114425383071
Relative roles of ABCG5/ABCG8 in liver and intestine.Wang, Jin; Mitsche, Matthew A; Lutjohann, Dieter; Cohen, Jonathan C; Xie, Xiao-Song; Hobbs, Helen HJournal of lipid research.2015 Feb;319-3025378657
An expanding universe of mRNA modifications.Jaffrey, Samie RNature structural & molecular biology.2014 Nov;25372308
Identifying individual differences of fluoxetine response in juvenile rhesus monkeys by metabolite profiling.He, Y; Hogrefe, C E; Grapov, D; Palazoglu, M; Fiehn, O; Turck, C W; Golub, M STranslational psychiatry.2014;e47825369145
LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNF* treatment.Kamleh, Muhammad Anas; Snowden, Stuart G; Grapov, Dmitry; Blackburn, Gavin J; Watson, David G; Xu, Ning; Stahle, Mona; Wheelock, Craig EJournal of proteome research.2015 Jan 2;557-6625361234
Rapid-throughput glycomics applied to human milk oligosaccharide profiling for large human studies.Totten, Sarah M; Wu, Lauren D; Parker, Evan A; Davis, Jasmine C C; Hua, Serenus; Stroble, Carol; Ruhaak, L Renee; Smilowitz, Jennifer T; German, J Bruce; Lebrilla, Carlito BAnalytical and bioanalytical chemistry.2014 Dec;7925-3525358913
Urinary metabolite profiling combined with computational analysis predicts interstitial cystitis-associated candidate biomarkers.Wen, He; Lee, Tack; You, Sungyong; Park, Soo-Hwan; Song, Hosook; Eilber, Karyn S; Anger, Jennifer T; Freeman, Michael R; Park, Sunghyouk; Kim, JayoungJournal of proteome research.2015 Jan 2;541-825353990
LipidBlast templates as flexible tools for creating new in-silico tandem mass spectral libraries.Kind, Tobias; Okazaki, Yozo; Saito, Kazuki; Fiehn, OliverAnalytical chemistry.2014 Nov 18;11024-725340521
The human colostrum whey proteome is altered in gestational diabetes mellitus.Grapov, Dmitry; Lemay, Danielle G; Weber, Darren; Phinney, Brett S; Azulay Chertok, Ilana R; Gho, Deborah S; German, J Bruce; Smilowitz, Jennifer TJournal of proteome research.2015 Jan 2;512-2025338220
Unified and isomer-specific NMR metabolomics database for the accurate analysis of (13)C-(1)H HSQC spectra.Bingol, Kerem; Li, Da-Wei; Bruschweiler-Li, Lei; Cabrera, Oscar A; Megraw, Timothy; Zhang, Fengli; Bruschweiler, RafaelACS chemical biology.2015 Feb 20;452-925333826
Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.Scher, Jose U; Ubeda, Carles; Artacho, Alejandro; Attur, Mukundan; Isaac, Sandrine; Reddy, Soumya M; Marmon, Shoshana; Neimann, Andrea; Brusca, Samuel; Patel, Tejas; Manasson, Julia; Pamer, Eric G; Littman, Dan R; Abramson, Steven BArthritis & rheumatology (Hoboken, N.J.).2015 Jan;25319745
Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry.Cajka, Tomas; Fiehn, OliverTrends in analytical chemistry : TRAC.2014 Oct 1;192-20625309011
Development of an analytical method for assessment of silver nanoparticle content in biological matrices by inductively coupled plasma mass spectrometry.Poitras, Eric P; Levine, Michael A; Harrington, James M; Essader, Amal S; Fennell, Timothy R; Snyder, Rodney W; Black, Sherry L; Sumner, Susan S; Levine, Keith EBiological trace element research.2015 Feb;184-9225308764
Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster.Williams, Caroline M; Watanabe, Miki; Guarracino, Mario R; Ferraro, Maria B; Edison, Arthur S; Morgan, Theodore J; Boroujerdi, Arezue F B; Hahn, Daniel AEvolution; international journal of organic evolution.2014 Dec;3505-2325308124
Time lag of glucose from intravascular to interstitial compartment in type 1 diabetes.Basu, Ananda; Dube, Simmi; Veettil, Sona; Slama, Michael; Kudva, Yogish C; Peyser, Thomas; Carter, Rickey E; Cobelli, Claudio; Basu, RitaJournal of diabetes science and technology.2015 Jan;63-825305282
11*-hydroxysteroid dehydrogenase types 1 and 2 activity in subcutaneous adipose tissue in humans: implications in obesity and diabetes.Dube, Simmi; Norby, Barbara J; Pattan, Vishwanath; Carter, Rickey E; Basu, Ananda; Basu, RitaThe Journal of clinical endocrinology and metabolism.2015 Jan;E70-625303491
Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut.Underwood, Mark A; German, J Bruce; Lebrilla, Carlito B; Mills, David APediatric research.2015 Jan;229-3525303277
The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings.Noto, Antonio; Fanos, Vassilios; Barberini, Luigi; Grapov, Dmitry; Fattuoni, Claudia; Zaffanello, Marco; Casanova, Andrea; Fenu, Gianni; De Giacomo, Andrea; De Angelis, Maria; Moretti, Corrado; Papoff, Paola; Ditonno, Raffaella; Francavilla, RuggieroThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.2014 Oct;46-5225284177
Urinary metabolomics (GC-MS) reveals that low and high birth weight infants share elevated inositol concentrations at birth.Barberini, Luigi; Noto, Antonio; Fattuoni, Claudia; Grapov, Dmitry; Casanova, Andrea; Fenu, Gianni; Gaviano, Mauro; Carboni, Roberta; Ottonello, Giovanni; Crisafulli, Maurizio; Fanos, Vassilios; Dessi, AngelicaThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.2014 Oct;20-625284173
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.Moon, Young-Ah; Ochoa, Courtney R; Mitsche, Matthew A; Hammer, Robert E; Horton, Jay DJournal of lipid research.2014 Dec;2597-60525281760
Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS.Higashi, Richard M; Fan, Teresa W-M; Lorkiewicz, Pawel K; Moseley, Hunter N B; Lane, Andrew NMethods in molecular biology (Clifton, N.J.).2014;147-6725270929
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase.Inloes, Jordon M; Hsu, Ku-Lung; Dix, Melissa M; Viader, Andreu; Masuda, Kim; Takei, Thais; Wood, Malcolm R; Cravatt, Benjamin FProceedings of the National Academy of Sciences of the United States of America.2014 Oct 14;14924-925267624
MS2Analyzer: A software for small molecule substructure annotations from accurate tandem mass spectra.Ma, Yan; Kind, Tobias; Yang, Dawei; Leon, Carlos; Fiehn, OliverAnalytical chemistry.2014 Nov 4;10724-3125263576
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.Sporkova, Alexandra; Jichova, Sarka; Huskova, Zuzana; Kopkan, Libor; Nishiyama, Akira; Hwang, Sung H; Hammock, Bruce D; Imig, John D; Kompanowska-Jezierska, Elzbieta; Sadowski, Janusz; Kramer, Herbert J; Cervenka, LudekClinical and experimental pharmacology & physiology.2014 Dec;1003-1325224811
High insulin combined with essential amino acids stimulates skeletal muscle mitochondrial protein synthesis while decreasing insulin sensitivity in healthy humans.Robinson, Matthew M; Soop, Mattias; Sohn, Tae Seo; Morse, Dawn M; Schimke, Jill M; Klaus, Katherine A; Nair, K SreekumaranThe Journal of clinical endocrinology and metabolism.2014 Dec;E2574-8325222757
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.Kenny, Hilary A; Chiang, Chun-Yi; White, Erin A; Schryver, Elizabeth M; Habis, Mohammed; Romero, Iris L; Ladanyi, Andras; Penicka, Carla V; George, Joshy; Matlin, Karl; Montag, Anthony; Wroblewski, Kristen; Yamada, S Diane; Mazar, Andrew P; Bowtell, David; Lengyel, ErnstThe Journal of clinical investigation.2014 Oct;25202979
Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid.Abu-Soud, Husam M; Maitra, Dhiman; Shaeib, Faten; Khan, Sana N; Byun, Jaeman; Abdulhamid, Ibrahim; Yang, Zhe; Saed, Ghassan M; Diamond, Michael P; Andreana, Peter R; Pennathur, SubramaniamJournal of inorganic biochemistry.2014 Nov;245-5425193127
Effects of increased free fatty acid availability on adipose tissue fatty acid storage in men.Mundi, Manpreet S; Koutsari, Chistina; Jensen, Michael DThe Journal of clinical endocrinology and metabolism.2014 Dec;E2635-4225192251
Crucial role of macrophage selenoproteins in experimental colitis.Kaushal, Naveen; Kudva, Avinash K; Patterson, Andrew D; Chiaro, Christopher; Kennett, Mary J; Desai, Dhimant; Amin, Shantu; Carlson, Bradley A; Cantorna, Margherita T; Prabhu, K SandeepJournal of immunology (Baltimore, Md. : 1950).2014 Oct 1;3683-9225187657
Comparative evaluation of extraction methods for simultaneous mass-spectrometric analysis of complex lipids and primary metabolites from human blood plasma.Lee, Do Yup; Kind, Tobias; Yoon, Young-Ran; Fiehn, Oliver; Liu, Kwang-HyeonAnalytical and bioanalytical chemistry.2014 Nov;7275-8625171832
Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma.Ono, Emiko; Dutile, Stefanie; Kazani, Shamsah; Wechsler, Michael E; Yang, Jun; Hammock, Bruce D; Douda, David Nobuhiro; Tabet, Yacine; Khaddaj-Mallat, Rayan; Sirois, Marco; Sirois, Chantal; Rizcallah, Edmond; Rousseau, Eric; Martin, Richard; Sutherland, E Rand; Castro, Mario; Jarjour, Nizar N; Israel, Elliot; Levy, Bruce D; National Heart, Lung, and Blood Institute's Asthma Clinical Research NetworkAmerican journal of respiratory and critical care medicine.2014 Oct 15;886-9725162465
Credentialing features: a platform to benchmark and optimize untargeted metabolomic methods.Mahieu, Nathaniel Guy; Huang, Xiaojing; Chen, Ying-Jr; Patti, Gary JAnalytical chemistry.2014 Oct 7;9583-925160088
Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology.Patterson, Andrew D; Turnbaugh, Peter JCell metabolism2014 Aug 20NULL25156450
Glutamate enrichment as new diagnostic opportunity in breast cancer.Budczies, Jan; Pfitzner, Berit M; Gyorffy, Balazs; Winzer, Klaus-Jurgen; Radke, Cornelia; Dietel, Manfred; Fiehn, Oliver; Denkert, CarstenInternational journal of cancer. Journal international du cancer.2015 Apr 1;1619-2825155347
Inflammation triggers production of dimethylsphingosine from oligodendrocytes.Chen, Y-J; Hill, S; Huang, H; Taraboletti, A; Cho, K; Gallo, R; Manchester, M; Shriver, L P; Patti, G JNeuroscience.2014 Oct 24;113-2125151189
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.Despa, Sanda; Sharma, Savita; Harris, Todd R; Dong, Hua; Li, Ning; Chiamvimonvat, Nipavan; Taegtmeyer, Heinrich; Margulies, Kenneth B; Hammock, Bruce D; Despa, FlorinJournal of the American Heart Association2014 AugNULL25146704
Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.Hu, Biao; Liu, Jianhua; Wu, Zhe; Liu, Tianju; Ullenbruch, Matthew R; Ding, Lin; Henke, Craig A; Bitterman, Peter B; Phan, Sem HAmerican journal of respiratory cell and molecular biology.2015 Apr;418-2825140582
¹³C NMR metabolomics: applications at natural abundance.Clendinen, Chaevien S; Lee-McMullen, Brittany; Williams, Caroline M; Stupp, Gregory S; Vandenborne, Krista; Hahn, Daniel A; Walter, Glenn A; Edison, Arthur SAnalytical chemistry.2014 Sep 16;9242-5025140385
Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics.Mitchell, Joshua M; Fan, Teresa W-M; Lane, Andrew N; Moseley, Hunter N BFrontiers in genetics.2014;23725120557
Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation.Noori, S; McNamara, P; Jain, A; Lavoie, P M; Wickremasinghe, A; Merritt, T A; Solomon, T; Sekar, K; Attridge, J T; Swanson, J R; Gillam-Krakauer, M; Reese, J; Poindexter, B B; Brook, M; Auchus, R J; Clyman, R I; PDA Ligation/Hypotension Trial InvestigatorsJournal of perinatology : official journal of the California Perinatal Association.2015 Feb;123-725118721
Statin therapy is associated with improved survival in patients with non-serous-papillary epithelial ovarian cancer: a retrospective cohort analysis.Habis, Mohammed; Wroblewski, Kristen; Bradaric, Michael; Ismail, Nadia; Yamada, S Diane; Litchfield, Lacey; Lengyel, Ernst; Romero, Iris LPloS one.2014;25118694
Structural analysis of N- and O-glycans using ZIC-HILIC/dialysis coupled to NMR detection.Qu, Yi; Feng, Ju; Deng, Shuang; Cao, Li; Zhang, Qibin; Zhao, Rui; Zhang, Zhaorui; Jiang, Yuxuan; Zink, Erika M; Baker, Scott E; Lipton, Mary S; Pasa-Tolic, Ljiljana; Hu, Jian Zhi; Wu, SiFungal genetics and biology : FG & B.2014 Nov;207-1525117693
Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.Hayashi, Genki; Shen, Yan; Pedersen, Theresa L; Newman, John W; Pook, Mark; Cortopassi, GinoHuman molecular genetics.2014 Dec 20;6838-4725104852
Increasing Confidence of LC-MS Identifications by Utilizing Ion Mobility Spectrometry.Crowell, Kevin L; Baker, Erin S; Payne, Samuel H; Ibrahim, Yehia M; Monroe, Matthew E; Slysz, Gordon W; LaMarche, Brian L; Petyuk, Vladislav A; Piehowski, Paul D; Danielson 3rd, William F; Anderson, Gordon A; Smith, Richard DInternational journal of mass spectrometry.2013 Nov 15;312-31725089116
PVP formulated fullerene (C60) increases Rho-kinase dependent vascular tissue contractility in pregnant Sprague Dawley rats.Vidanapathirana, Achini K; Thompson, Leslie C; Mann, Erin E; Odom, Jillian T; Holland, Nathan A; Sumner, Susan J; Han, Li; Lewin, Anita H; Fennell, Timothy R; Brown, Jared M; Wingard, Christopher JReproductive toxicology (Elmsford, N.Y.).2014 Nov;86-10025088243
Perinatal exposure of mice to the pesticide DDT impairs energy expenditure and metabolism in adult female offspring.La Merrill, Michele; Karey, Emma; Moshier, Erin; Lindtner, Claudia; La Frano, Michael R; Newman, John W; Buettner, ChristophPloS one.2014;e10333725076055
Proteasome function is required for platelet production.Shi, Dallas S; Smith, Matthew C P; Campbell, Robert A; Zimmerman, Patrick W; Franks, Zechariah B; Kraemer, Bjorn F; Machlus, Kellie R; Ling, Jing; Kamba, Patrick; Schwertz, Hansjorg; Rowley, Jesse W; Miles, Rodney R; Liu, Zhi-Jian; Sola-Visner, Martha; Italiano Jr, Joseph E; Christensen, Hilary; Kahr, Walter H A; Li, Dean Y; Weyrich, Andrew SThe Journal of clinical investigation.2014 Sep;3757-6625061876
Thermally-Induced Substrate Release Via Intramolecular Cyclizations of Amino Esters and Amino Carbonates.Knipp, Ralph J; Estrada, Rosendo; Sethu, Palaniappan; Nantz, Michael HTetrahedron2014 May 13422-342925061237
Tracing flavonoid degradation in grapes by MS filtering with stable isotopes.Chassy, Alexander W; Bueschl, Christoph; Lee, Hyeyoung; Lerno, Larry; Oberholster, Anita; Barile, Daniela; Schuhmacher, Rainer; Waterhouse, Andrew LFood chemistry2015 Jan 1448-5525053079
The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects.Sathananthan, Matheni; Ikramuddin, Sayeed; Swain, James M; Shah, Meera; Piccinini, Francesca; Dalla Man, Chiara; Cobelli, Claudio; Rizza, Robert A; Camilleri, Michael; Vella, AdrianDiabetes, metabolic syndrome and obesity : targets and therapy.2014;305-1225050073
Three-dimensional modeling of ovarian cancer.White, Erin A; Kenny, Hilary A; Lengyel, ErnstAdvanced drug delivery reviews.2014 Dec 15;25034878
Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling.Vendelbo, Mikkel Holm; Moller, Andreas Buch; Christensen, Britt; Nellemann, Birgitte; Clasen, Berthil Frederik Forrest; Nair, K Sreekumaran; Jorgensen, Jens Otto Lunde; Jessen, Niels; Moller, NielsPloS one.2014;e10203125020061
Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.Zallot, Remi; Yazdani, Mohammad; Goyer, Aymeric; Ziemak, Michael J; Guan, Jiahn-Chou; McCarty, Donald R; de Crecy-Lagard, Valerie; Gerdes, Svetlana; Garrett, Timothy J; Benach, Jordi; Hunt, John F; Shintani, David K; Hanson, Andrew DThe Biochemical journal.2014 Oct 1;145-5525014715
Differential incorporation of glucose into biomass during Warburg metabolism.Chen, Ying-Jr; Huang, Xiaojing; Mahieu, Nathaniel G; Cho, Kevin; Schaefer, Jacob; Patti, Gary JBiochemistry.2014 Jul 29;4755-725010499
Enhanced detection and identification in metabolomics by use of LC-MS/MS untargeted analysis in combination with gas-phase fractionation.Calder�n-Santiago, M�nica; Priego-Capote, Feliciano; Luque de Castro, Mar�a DAnalytical chemistry2014 Aug 524992377
Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.Jourdan, Marion; Nair, K Sreekumaran; Carter, Rickey E; Schimke, Jill; Ford, G Charles; Marc, Julie; Aussel, Christian; Cynober, LucClinical nutrition (Edinburgh, Scotland).2015 Jun;449-5624972455
Studies of Secondary Melanoma on C57BL/6J Mouse Liver Using 1H NMR Metabolomics.Feng, Ju; Isern, Nancy G; Burton, Sarah D; Hu, Jian ZhiMetabolites.2013;1011-3524958263
Tryptophan catabolism restricts IFN-ýý-expressing neutrophils and Clostridium difficile immunopathology.El-Zaatari, Mohamad; Chang, Yu-Ming; Zhang, Min; Franz, Matthew; Shreiner, Andrew; McDermott, Andrew J; van der Sluijs, Koenraad F; Lutter, Rene; Grasberger, Helmut; Kamada, Nobuhiko; Young, Vincent B; Huffnagle, Gary B; Kao, John YJournal of immunology (Baltimore, Md. : 1950)2014 Jul 15807-1624935925
Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses.Gowda, Harsha; Ivanisevic, Julijana; Johnson, Caroline H; Kurczy, Michael E; Benton, H Paul; Rinehart, Duane; Nguyen, Thomas; Ray, Jayashree; Kuehl, Jennifer; Arevalo, Bernardo; Westenskow, Peter D; Wang, Junhua; Arkin, Adam P; Deutschbauer, Adam M; Patti, Gary J; Siuzdak, GaryAnalytical chemistry.2014 Jul 15;6931-924934772
Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice.Yang, Jun; Bratt, Jennifer; Franzi, Lisa; Liu, Jun-Yan; Zhang, Guodong; Zeki, Amir A; Vogel, Christoph F A; Williams, Keisha; Dong, Hua; Lin, Yanping; Hwang, Sung Hee; Kenyon, Nicholas J; Hammock, Bruce DAmerican journal of respiratory cell and molecular biology.2015 Jan;46-5524922186
Analysis of Human Serum and Whole Blood for Mineral Content by ICP-MS and ICP-OES: Development of a Mineralomics Method.Harrington, James M; Young, Daniel J; Essader, Amal S; Sumner, Susan J; Levine, Keith EBiological trace element research2014 Jun 11NULL24917052
Metabolomic data streaming for biology-dependent data acquisition.Rinehart, Duane; Johnson, Caroline H; Nguyen, Thomas; Ivanisevic, Julijana; Benton, H Paul; Lloyd, Jessica; Arkin, Adam P; Deutschbauer, Adam M; Patti, Gary J; Siuzdak, GaryNature biotechnology2014 Jun524-724911492
A tour through the transcriptional landscape of platelets.Schubert, Sebastian; Weyrich, Andrew S; Rowley, Jesse WBlood2014 Jul 24493-50224904119
Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins.Schebb, Nils Helge; Ostermann, Annika I; Yang, Jun; Hammock, Bruce D; Hahn, Andreas; Schuchardt, Jan PhilippProstaglandins & other lipid mediators2014 May 29NULL24880049
Mechanisms of buffer therapy resistance.Bailey, Kate M; Wojtkowiak, Jonathan W; Cornnell, Heather H; Ribeiro, Maria C; Balagurunathan, Yoganand; Hashim, Arig Ibrahim; Gillies, Robert JNeoplasia (New York, N.Y.).2014 Apr;24862761
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.Gori, Sadakatali S; Lorkiewicz, Pawel; Ehringer, Daniel S; Belshoff, Alex C; Higashi, Richard M; Fan, Teresa W-M; Nantz, Michael HAnalytical and bioanalytical chemistry2014 Jul4371-924858467
Microbiota, oral microbiome, and pancreatic cancer.Michaud, Dominique S; Izard, JacquesCancer journal (Sudbury, Mass.)2014 May-Jun203-624855008
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.Church, Rachel J; Wu, Hong; Mosedale, Merrie; Sumner, Susan J; Pathmasiri, Wimal; Kurtz, Catherine L; Pletcher, Mathew T; Eaddy, John S; Pandher, Karamjeet; Singer, Monica; Batheja, Ameesha; Watkins, Paul B; Adkins, Karissa; Harrill, Alison HToxicological sciences : an official journal of the Society of Toxicology2014 Aug 1481-9224848797
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.Charles, Rebecca L; Rudyk, Olena; Prysyazhna, Oleksandra; Kamynina, Alisa; Yang, Jun; Morisseau, Christophe; Hammock, Bruce D; Freeman, Bruce A; Eaton, PhilipProceedings of the National Academy of Sciences of the United States of America2014 Jun 38167-7224843165
Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation.Avanesov, Andrei S; Ma, Siming; Pierce, Kerry A; Yim, Sun Hee; Lee, Byung Cheon; Clish, Clary B; Gladyshev, Vadim NeLife2014e0207724843015
Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: An additional proatherogenic mechanism in systemic lupus erythematosus.Smith, Carolyne K; Vivekanandan-Giri, Anuradha; Tang, Chongren; Knight, Jason S; Mathew, Anna; Padilla, Robin L; Gillespie, Brenda W; Carmona-Rivera, Carmelo; Liu, Xiaodan; Subramanian, Venkataraman; Hasni, Sarfaraz; Thompson, Paul R; Heinecke, Jay W; SarArthritis & rheumatology (Hoboken, N.J.)2014 May 16NULL24838349
Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells.da Silva, Vanessa R; Ralat, Maria A; Quinlivan, Eoin P; DeRatt, Barbara N; Garrett, Timothy J; Chi, Yueh-Yun; Frederik Nijhout, H; Reed, Michael C; Gregory 3rd, Jesse FAmerican journal of physiology. Endocrinology and metabolism.2014 Jul 1;24824655
After the feature presentation: technologies bridging untargeted metabolomics and biology.Cho, Kevin; Mahieu, Nathaniel G; Johnson, Stephen L; Patti, Gary JCurrent opinion in biotechnology2014 May 5143-14824816495
Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group.Deutz, Nicolaas E P; Bauer, Jurgen M; Barazzoni, Rocco; Biolo, Gianni; Boirie, Yves; Bosy-Westphal, Anja; Cederholm, Tommy; Cruz-Jentoft, Alfonso; Krznaric, Zeljko; Nair, K Sreekumaran; Singer, Pierre; Teta, Daniel; Tipton, Kevin; Calder, Philip CClinical nutrition (Edinburgh, Scotland).2014 Dec;929-3624814383
Quantitative NMR Metabolite Profiling of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Discriminates between Biofilm and Planktonic Phenotypes.Ammons, Mary Cloud B; Tripet, Brian P; Carlson, Ross P; Kirker, Kelly R; Gross, Michael A; Stanisich, Jessica J; Copie, ValerieJournal of proteome research2014 Jun 62973-8524809402
Gastrointestinal microbes interact with canine adipose-derived mesenchymal stem cells in vitro and enhance immunomodulatory functions.Kol, Amir; Foutouhi, Soraya; Walker, Naomi J; Kong, Nguyet T; Weimer, Bart C; Borjesson, Dori LStem cells and development.2014 Aug 15;1831-4324803072
Detecting and Removing Data Artifacts in Hadamard Transform Ion Mobility-Mass Spectrometry Measurements.Prost, Spencer A; Crowell, Kevin L; Baker, Erin S; Ibrahim, Yehia M; Clowers, Brian H; Monroe, Matthew E; Anderson, Gordon A; Smith, Richard D; Payne, Samuel HJournal of the American Society for Mass Spectrometry2014 May 6NULL24796262
Improving Ion Mobility Measurement Sensitivity by Utilizing Helium in an Ion Funnel Trap.Ibrahim, Yehia M; Garimella, Sandilya V B; Tolmachev, Aleksey V; Baker, Erin S; Smith, Richard DAnalytical chemistry2014 May 13NULL24786390
Customized Metabolomics Database for the Analysis of NMR (1)H-(1)H TOCSY and (13)C-(1)H HSQC-TOCSY Spectra of Complex Mixtures.Bingol, Kerem; Bruschweiler-Li, Lei; Li, Da-Wei; Bruschweiler, RafaelAnalytical chemistry2014 May 20NULL24773139
A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.Lanning, Nathan J; Looyenga, Brendan D; Kauffman, Audra L; Niemi, Natalie M; Sudderth, Jessica; DeBerardinis, Ralph J; MacKeigan, Jeffrey PCell reports2014 May 8907-1724767988
mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.Fort, Patrice E; Losiewicz, Mandy K; Pennathur, Subramaniam; Jefferson, Leonard S; Kimball, Scot R; Abcouwer, Steven F; Gardner, Thomas WDiabetes.2014 Sep;3077-9024740573
Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer.Mathe, Ewy A; Patterson, Andrew D; Haznadar, Majda; Manna, Soumen K; Krausz, Kristopher W; Bowman, Elise D; Shields, Peter G; Idle, Jeffrey R; Smith, Philip B; Anami, Katsuhiro; Kazandjian, Dickran G; Hatzakis, Emmanuel; Gonzalez, Frank J; Harris, Curtis Cancer research2014 Jun 153259-7024736543
Racial and ethnic differences in older adults with knee osteoarthritis.Cruz-Almeida, Yenisel; Sibille, Kimberly T; Goodin, Burel R; Petrov, Megan E; Bartley, Emily J; Riley 3rd, Joseph L; King, Christopher D; Glover, Toni L; Sotolongo, Adriana; Herbert, Matthew S; Schmidt, Jessica K; Fessler, Barri J; Staud, Roland; Redden, David; Bradley, Laurence A; Fillingim, Roger BArthritis & rheumatology (Hoboken, N.J.).2014 Jul;24729357
Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.Xie, Han; Hanai, Jun-Ichi; Ren, Jian-Guo; Kats, Lev; Burgess, Kerri; Bhargava, Parul; Signoretti, Sabina; Billiard, Julia; Duffy, Kevin J; Grant, Aaron; Wang, Xiaoen; Lorkiewicz, Pawel K; Schatzman, Sabrina; Bousamra 2nd, Michael; Lane, Andrew N; Higashi,Cell metabolism2014 May 6795-80924726384
Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.Nishizawa, Tomohiro; Kanter, Jenny E; Kramer, Farah; Barnhart, Shelley; Shen, Xia; Vivekanandan-Giri, Anuradha; Wall, Valerie Z; Kowitz, Jason; Devaraj, Sridevi; O'Brien, Kevin D; Pennathur, Subramaniam; Tang, Jingjing; Miyaoka, Robert S; Raines, Elaine WCell reports2014 Apr 24356-6524726364
MR microscopy of formalin fixed paraffin embedded histology specimens.Macura, Slobodan; Mishra, Prasanna K; Gamez, Jeffrey D; Pirko, IstvanMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine2014 Jun1989-9424715442
The dynamic epitranscriptome: N6-methyladenosine and gene expression control.Meyer, Kate D; Jaffrey, Samie RNature reviews. Molecular cell biology.2014 May;24713629
MetDisease--connecting metabolites to diseases via literature.Duren, William; Weymouth, Terry; Hull, Tim; Omenn, Gilbert S; Athey, Brian; Burant, Charles; Karnovsky, AllaBioinformatics (Oxford, England)2014 Apr 23NULL24713438
LC-MS-based metabolomics: an update.Fang, Zhong-Ze; Gonzalez, Frank JArchives of toxicology.2014 Aug;1491-50224710571
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.Guin, Sunny; Pollard, Courtney; Ru, Yuanbin; Ritterson Lew, Carolyn; Duex, Jason E; Dancik, Garrett; Owens, Charles; Spencer, Andrea; Knight, Scott; Holemon, Heather; Gupta, Sounak; Hansel, Donna; Hellerstein, Marc; Lorkiewicz, Pawel; Lane, Andrew N; Fan,Journal of the National Cancer Institute2014 MayNULL24700805
An Omega-3 Epoxide of Docosahexaenoic Acid Lowers Blood Pressure in Angiotensin-II Dependent Hypertension.Ulu, Arzu; Stephen Lee, Kin Sing; Miyabe, Christina; Yang, Jun; Hammock, Bruce G; Dong, Hua; Hammock, Bruce DJournal of cardiovascular pharmacology2014 Mar 31NULL24691274
Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets.O'Donnell, Valerie B; Murphy, Robert C; Watson, Steve PCirculation research2014 Mar 281185-20324677238
Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion.El-Azzouny, Mahmoud; Evans, Charles R; Treutelaar, Mary K; Kennedy, Robert T; Burant, Charles FThe Journal of biological chemistry2014 May 913575-8824675078
Continuous 24-Hour Leptin, Proopiomelanocortin and Amino Acid Measurements in Human Cerebrospinal Fluid: Correlations with Plasma Leptin, Soluble Leptin Receptor and Amino Acid Levels.Wardlaw, Sharon L; Burant, Charles F; Klein, Samuel; Meece, Kana; White, Anne; Kasten, Tom; Lucey, Brendan P; Bateman, Randall JThe Journal of clinical endocrinology and metabolism2014 Mar 26jc2013408724670082
Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA.Schuchardt, Jan Philipp; Schneider, Inga; Willenberg, Ina; Yang, Jun; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins & other lipid mediators2014 Jun23-3124667634
Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.Guzun, R; Kaambre, T; Bagur, R; Grichine, A; Usson, Y; Varikmaa, M; Anmann, T; Tepp, K; Timohhina, N; Shevchuk, I; Chekulayev, V; Boucher, F; Dos Santos, P; Schlattner, U; Wallimann, T; Kuznetsov, A V; Dzeja, P; Aliev, M; Saks, VActa physiologica (Oxford, England)2014 Mar 26NULL24666671
Leucine modulates dynamic phosphorylation events in insulin signaling pathway and enhances insulin-dependent glycogen synthesis in human skeletal muscle cells.Di Camillo, Barbara; Eduati, Federica; Nair, Sreekumaran K; Avogaro, Angelo; Toffolo, Gianna MBMC cell biology.2014;924646332
Potential biomarker of metformin action.He, Ling; Meng, Shumei; Germain-Lee, Emily L; Radovick, Sally; Wondisford, Fredric EThe Journal of endocrinology.2014 Jun;24639469
Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones.Clyman, Ronald I; Wickremasinghe, Andrea; Merritt, T Allen; Solomon, Tabitha; McNamara, Patrick; Jain, Amish; Singh, Jaideep; Chu, Alison; Noori, Shahab; Sekar, Krishnamurthy; Lavoie, Pascal M; Attridge, Joshua T; Swanson, Jonathan R; Gillam-Krakauer, MarThe Journal of pediatrics2014 Jun1449-55.e124636853
Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives.Garay, Luis A; Boundy-Mills, Kyria L; German, J BruceJournal of agricultural and food chemistry2014 Apr 22709-2724628496
Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome.Roberts, Lee D; Koulman, Albert; Griffin, Julian LThe lancet. Diabetes & endocrinology2014 Jan65-7524622670
Tracing phenolic metabolism in Vitis vinifera berries with 13C6-phenylalanine: implication of an unidentified intermediate reservoir.Chassy, Alexander W; Adams, Douglas O; Waterhouse, Andrew LJournal of agricultural and food chemistry2014 Mar 192321-624611798
Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection.Bassis, Christine M; Theriot, Casey M; Young, Vincent BAntimicrobial agents and chemotherapy2014 May2767-7424590475
Reproducibility of magnetic resonance perfusion imaging.Zhang, Xiaomeng; Pagel, Mark D; Baker, Amanda F; Gillies, Robert JPloS one.2014;24587040
Relationship of muscle sympathetic nerve activity to insulin sensitivity.Curry, Timothy B; Hines, Casey N; Barnes, Jill N; Somaraju, Madhuri; Basu, Rita; Miles, John M; Joyner, Michael J; Charkoudian, NishaClinical autonomic research : official journal of the Clinical Autonomic Research Society.2014 Apr;77-8524577625
Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa.Phelan, Vanessa V; Moree, Wilna J; Aguilar, Julieta; Cornett, Dale S; Koumoutsi, Alexandra; Noble, Suzanne M; Pogliano, Kit; Guerrero, Carlos A; Dorrestein, Pieter CJournal of bacteriology2014 May1683-9324532776
Janus-faced tumor microenvironment and redox.Khramtsov, Valery V; Gillies, Robert JAntioxidants & redox signaling.2014 Aug 10;24512276
A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue.Bisht, Babita; Darling, Warren G; Grossmann, Ruth E; Shivapour, E Torage; Lutgendorf, Susan K; Snetselaar, Linda G; Hall, Michael J; Zimmerman, M Bridget; Wahls, Terry LJournal of alternative and complementary medicine (New York, N.Y.).2014 May;347-5524476345
Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females.Parlee, Sebastian D; Simon, Becky R; Scheller, Erica L; Alejandro, Emilyn U; Learman, Brian S; Krishnan, Venkatesh; Bernal-Mizrachi, Ernesto; MacDougald, Ormond AEndocrinology2014 Apr1313-2624456165
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Theriot, Casey M; Koenigsknecht, Mark J; Carlson Jr, Paul E; Hatton, Gabrielle E; Nelson, Adam M; Li, Bo; Huffnagle, Gary B; Z Li, Jun; Young, Vincent BNature communications2014311424445449
Cýýýýýý exposure augments cardiac ischemia/reperfusion injury and coronary artery contraction in Sprague Dawley rats.Thompson, Leslie C; Urankar, Rakhee N; Holland, Nathan A; Vidanapathirana, Achini K; Pitzer, Joshua E; Han, Li; Sumner, Susan J; Lewin, Anita H; Fennell, Timothy R; Lust, Robert M; Brown, Jared M; Wingard, Christopher JToxicological sciences : an official journal of the Society of Toxicology.2014 Apr;365-7824431213
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.Niewczas, Monika A; Sirich, Tammy L; Mathew, Anna V; Skupien, Jan; Mohney, Robert P; Warram, James H; Smiles, Adam; Huang, Xiaoping; Walker, Walker; Byun, Jaeman; Karoly, Edward D; Kensicki, Elizabeth M; Berry, Gerard T; Bonventre, Joseph V; Pennathur, SuKidney international2014 Jan 15NULL24429397
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.Campbell, Caitlin; Grapov, Dmitry; Fiehn, Oliver; Chandler, Carol J; Burnett, Dustin J; Souza, Elaine C; Casazza, Gretchen A; Gustafson, Mary B; Keim, Nancy L; Newman, John W; Hunter, Gary R; Fernandez, Jose R; Garvey, W Timothy; Harper, Mary-Ellen; HoppePloS one2014e8426024416208
Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2014 Feb-Mar27-3724411718
A Computational Framework for High-Throughput Isotopic Natural Abundance Correction of Omics-Level Ultra-High Resolution FT-MS Datasets.Carreer, William J; Flight, Robert M; Moseley, Hunter N BMetabolites2013 Sep 25NULL24404440
Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry.Baker, Erin Shammel; Burnum-Johnson, Kristin E; Jacobs, Jon M; Diamond, Deborah L; Brown, Roslyn N; Ibrahim, Yehia M; Orton, Daniel J; Piehowski, Paul D; Purdy, David E; Moore, Ronald J; Danielson 3rd, William F; Monroe, Matthew E; Crowell, Kevin L; SlyszMolecular & cellular proteomics : MCP2014 Apr1119-2724403597
Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease.Shu, Liming; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Smid, Bouwien E; Aerts, Johannes M F G; Hollak, Carla E M; Shayman, James AKidney international.2014 Jul;58-6624402087
X13CMS: global tracking of isotopic labels in untargeted metabolomics.Huang, Xiaojing; Chen, Ying-Jr; Cho, Kevin; Nikolskiy, Igor; Crawford, Peter A; Patti, Gary JAnalytical chemistry2014 Feb 41632-924397582
Control of Foxo1 gene expression by co-activator P300.Wondisford, Anne R; Xiong, Lishou; Chang, Evan; Meng, Shumei; Meyers, David J; Li, Mingsong; Cole, Philip A; He, LingThe Journal of biological chemistry.2014 Feb 14;24379407
Buffer Therapy for Cancer.Ribeiro, Maria de Lourdes C; Silva, Ariosto S; Bailey, Kate M; Kumar, Nagi B; Sellers, Thomas A; Gatenby, Robert A; Ibrahim-Hashim, Arig; Gillies, Robert JJournal of nutrition & food sciences.2012 Aug 15;24371544
Key role of microRNA in the regulation of granulocyte macrophage colony-stimulating factor expression in murine alveolar epithelial cells during oxidative stress.Sturrock, Anne; Mir-Kasimov, Mustafa; Baker, Jessica; Rowley, Jesse; Paine 3rd, RobertThe Journal of biological chemistry2014 Feb 144095-10524371146
Microbial and metabolic interactions between the gastrointestinal tract and Clostridium difficile infection.Theriot, Casey M; Young, Vincent BGut microbes.2014 Jan-Feb;86-9524335555
Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype.Ko, Song Yi; Ladanyi, Andras; Lengyel, Ernst; Naora, HonamiThe American journal of pathology.2014 Jan;24332016
Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice.Zhang, Wanying; Li, Haonan; Dong, Hua; Liao, Jie; Hammock, Bruce D; Yang, Guang-YuAnticancer research2013 Dec5261-7124324059
Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.Evans, Charles R; Karnovsky, Alla; Kovach, Melissa A; Standiford, Theodore J; Burant, Charles F; Stringer, Kathleen AJournal of proteome research2014 Feb 7640-924289193
Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI.Mignion, Lionel; Dutta, Prasanta; Martinez, Gary V; Foroutan, Parastou; Gillies, Robert J; Jordan, Bénédicte FCancer research.2014 Feb 1;24285723
Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging.O'Brien, Peter J; Lee, Michelle; Spilker, Mary E; Zhang, Cathy C; Yan, Zhengming; Nichols, Timothy C; Li, Wenlin; Johnson, Caroline H; Patti, Gary J; Siuzdak, GaryCancer & metabolism2013424280026
Isotopic Ratio Outlier Analysis Global Metabolomics of Caenorhabditis elegans.Stupp, Gregory S; Clendinen, Chaevien S; Ajredini, Ramadan; Szewc, Mark A; Garrett, Timothy; Menger, Robert F; Yost, Richard A; Beecher, Chris; Edison, Arthur SAnalytical chemistry2013 Dec 1711858-6524274725
Age and race effects on pain sensitivity and modulation among middle-aged and older adults.Riley 3rd, Joseph L; Cruz-Almeida, Yenisel; Glover, Toni L; King, Christopher D; Goodin, Burel R; Sibille, Kimberly T; Bartley, Emily J; Herbert, Matthew S; Sotolongo, Adriana; Fessler, Barri J; Redden, David T; Staud, Roland; Bradley, Laurence A; Fillingim, Roger BThe journal of pain : official journal of the American Pain Society.2014 Mar;24239561
Perceived racial discrimination, but not mistrust of medical researchers, predicts the heat pain tolerance of African Americans with symptomatic knee osteoarthritis.Goodin, Burel R; Pham, Quyen T; Glover, Toni L; Sotolongo, Adriana; King, Christopher D; Sibille, Kimberly T; Herbert, Matthew S; Cruz-Almeida, Yenisel; Sanden, Shelley H; Staud, Roland; Redden, David T; Bradley, Laurence A; Fillingim, Roger BHealth psychology : official journal of the Division of Health Psychology, American Psychological Association.2013 Nov;24219416
Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung.Yang, Jun; Solaimani, Parrisa; Dong, Hua; Hammock, Bruce; Hankinson, OliverThe Journal of toxicological sciences2013833-624213002
Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids.Nording, Malin L; Yang, Jun; Georgi, Katrin; Hegedus Karbowski, Christine; German, J Bruce; Weiss, Robert H; Hogg, Ronald J; Trygg, Johan; Hammock, Bruce D; Zivkovic, Angela MPloS one2013e7657524204640
Acid-mediated tumor proteolysis: contribution of cysteine cathepsins.Rothberg, Jennifer M; Bailey, Kate M; Wojtkowiak, Jonathan W; Ben-Nun, Yael; Bogyo, Matthew; Weber, Ekkehard; Moin, Kamiar; Blum, Galia; Mattingly, Raymond R; Gillies, Robert J; Sloane, Bonnie FNeoplasia (New York, N.Y.).2013 Oct;24204192
A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat.Ament, Zsuzsanna; Waterman, Claire L; West, James A; Waterfield, Catherine; Currie, Richard A; Wright, Jayne; Griffin, Julian LJournal of proteome research2013 Dec 65775-9024161236
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice.Schuster, Gertrud U; Bratt, Jennifer M; Jiang, Xiaowen; Pedersen, Theresa L; Grapov, Dmitry; Adkins, Yuriko; Kelley, Darshan S; Newman, John W; Kenyon, Nicholas J; Stephensen, Charles BAmerican journal of respiratory cell and molecular biology2014 Mar626-3624134486
Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis.Gardell, Alison M; Yang, Jun; Sacchi, Romina; Fangue, Nann A; Hammock, Bruce D; Kultz, DietmarThe Journal of experimental biology2013 Dec 154615-2524072790
Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors.Simon, Becky R; Parlee, Sebastian D; Learman, Brian S; Mori, Hiroyuki; Scheller, Erica L; Cawthorn, William P; Ning, Xiaomin; Gallagher, Katherine; Tyrberg, Björn; Assadi-Porter, Fariba M; Evans, Charles R; MacDougald, Ormond AThe Journal of biological chemistry.2013 Nov 8;24068707
Quantitative imaging in cancer evolution and ecology.Gatenby, Robert A; Grove, Olya; Gillies, Robert JRadiology.2013 Oct;24062559
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.Frolov, Andrey; Yang, Lihua; Dong, Hua; Hammock, Bruce D; Crofford, Leslie JProstaglandins, leukotrienes, and essential fatty acids2013 Oct351-824055573
Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.Ghanta, Sirisha; Grossmann, Ruth E; Brenner, CharlesCritical reviews in biochemistry and molecular biology2013 Nov-Dec561-7424050258
Human milk secretory immunoglobulin a and lactoferrin N-glycans are altered in women with gestational diabetes mellitus.Smilowitz, Jennifer T; Totten, Sarah M; Huang, Jincui; Grapov, Dmitry; Durham, Holiday A; Lammi-Keefe, Carol J; Lebrilla, Carlito; German, J BruceThe Journal of nutrition2013 Dec1906-1224047700
Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model.Ibrahim-Hashim, Arig; Wojtkowiak, Jonathan W; de Lourdes Coelho Ribeiro, Maria; Estrella, Veronica; Bailey, Kate M; Cornnell, Heather H; Gatenby, Robert A; Gillies, Robert JJournal of cancer science & therapy.2011 Nov 19;24032073
Can quantitative sensory testing move us closer to mechanism-based pain management?Cruz-Almeida, Yenisel; Fillingim, Roger BPain medicine (Malden, Mass.).2014 Jan;24010588
LC-IMS-MS Feature Finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets.Crowell, Kevin L; Slysz, Gordon W; Baker, Erin S; LaMarche, Brian L; Monroe, Matthew E; Ibrahim, Yehia M; Payne, Samuel H; Anderson, Gordon A; Smith, Richard DBioinformatics (Oxford, England)2013 Nov 12804-524008421
Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction.Hinder, Lucy M; Figueroa-Romero, Claudia; Pacut, Crystal; Hong, Yu; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Feldman, Eva LAntioxidants & redox signaling2013 Oct 5NULL23991914
Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola.Van Bogaert, Inge; Zhang, Guodong; Yang, Jun; Liu, Jun-Yan; Ye, Yonghao; Soetaert, Wim; Hammock, Bruce DJournal of lipid research2013 Nov3215-923966667
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.da Silva, Vanessa R; Rios-Avila, Luisa; Lamers, Yvonne; Ralat, Maria A; Midttun, Øivind; Quinlivan, Eoin P; Garrett, Timothy J; Coats, Bonnie; Shankar, Meena N; Percival, Susan S; Chi, Yueh-Yun; Muller, Keith E; Ueland, Per Magne; Stacpoole, Peter W; Gregory 3rd, Jesse FThe Journal of nutrition.2013 Nov;23966327
Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer.Wooding, Kerry M; Barkley, Robert M; Hankin, Joseph A; Johnson, Christopher A; Bradford, Andrew P; Santoro, Nanette; Murphy, Robert CJournal of the American Society for Mass Spectrometry2013 Oct1451-523955001
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.Perroud, Bertrand; Jafar-Nejad, Paymaan; Wikoff, William R; Gatchel, Jennifer R; Wang, Lu; Barupal, Dinesh K; Crespo-Barreto, Juan; Fiehn, Oliver; Zoghbi, Huda Y; Kaddurah-Daouk, RimaPloS one2013e7061023936457
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The isotridecanyl side chain of plusbacin-A3 is essential for the transglycosylase inhibition of peptidoglycan biosynthesis.Kim, Sung Joon; Singh, Manmilan; Wohlrab, Aaron; Yu, Tsyr-Yan; Patti, Gary J; O'Connor, Robert D; VanNieuwenhze, Michael; Schaefer, JacobBiochemistry2013 Mar 1923421534
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors.Dougherty, Joseph D; Maloney, Susan E; Wozniak, David F; Rieger, Michael A; Sonnenblick, Lisa; Coppola, Giovanni; Mahieu, Nathaniel G; Zhang, Juliet; Cai, Jinlu; Patti, Gary J; Abrahams, Brett S; Geschwind, Daniel H; Heintz, NathanielThe Journal of neuroscience : the official journal of the Society for Neuroscience.2013 Feb 13;2732-5323407934
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Variance of SUVs for FDG-PET/CT is greater in clinical practice than under ideal study settings.Kumar, Virendra; Nath, Kavindra; Berman, Claudia G; Kim, Jongphil; Tanvetyanon, Tawee; Chiappori, Alberto A; Gatenby, Robert A; Gillies, Robert J; Eikman, Edward AClinical nuclear medicine.2013 Mar;23354032
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Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.Wojtkowiak, Jonathan W; Rothberg, Jennifer M; Kumar, Virendra; Schramm, Karla J; Haller, Edward; Proemsey, Joshua B; Lloyd, Mark C; Sloane, Bonnie F; Gillies, Robert JCancer research.2012 Aug 15;22719070
A short-term diet and exercise intervention ameliorates inflammation and markers of metabolic health in overweight/obese children.Izadpanah, Ali; Barnard, R James; Almeda, Anna Jane E; Baldwin, Gayle C; Bridges, Sydney A; Shellman, Erin R; Burant, Charles F; Roberts, Christian KAmerican journal of physiology. Endocrinology and metabolism.2012 Aug 15;E542-5022713506
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A quantitative review of ethnic group differences in experimental pain response: do biology, psychology, and culture matter?Rahim-Williams, Bridgett; Riley 3rd, Joseph L; Williams, Ameenah K K; Fillingim, Roger BPain medicine (Malden, Mass.).2012 Apr;22390201
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The effects of 17?-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.Romero, Iris L; Lee, WooSeok; Mitra, Anirban K; Gordon, Ilyssa O; Zhao, Yan; Leonhardt, Payton; Penicka, Carla V; Mui, Keeley L; Krausz, Thomas N; Greene, Geoffrey L; Lengyel, ErnstGynecologic oncology.2012 Jan;21996264
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Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1.Boyerinas, Benjamin; Park, Sun-Mi; Murmann, Andrea E; Gwin, Katja; Montag, Anton G; Zillhardt, Marion; Hua, You-Jia; Lengyel, Ernst; Peter, Marcus EInternational journal of cancer.2012 Apr 15;21618519
Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T1 and T2 contrast agents.Martinez, Gary V; Zhang, Xiaomeng; García-Martín, María L; Morse, David L; Woods, Mark; Sherry, A Dean; Gillies, Robert JNMR in biomedicine.2011 Dec;21604311
Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis.Zillhardt, Marion; Park, Sun-Mi; Romero, Iris L; Sawada, Kenjiro; Montag, Anthony; Krausz, Thomas; Yamada, S Diane; Peter, Marcus E; Lengyel, ErnstClinical cancer research : an official journal of the American Association for Cancer Research.2011 Jun 15;21551255
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A phase II, single-arm study of the anti-*5*1 integrin antibody volociximab as monotherapy in patients with platinum-resistant advanced epithelial ovarian or primary peritoneal cancer.Bell-McGuinn, Katherine M; Matthews, Carolyn M; Ho, Steffan N; Barve, Minal; Gilbert, Lucy; Penson, Richard T; Lengyel, Ernst; Palaparthy, Rameshraja; Gilder, Kye; Vassos, Artemios; McAuliffe, William; Weymer, Sara; Barton, Jeremy; Schilder, Russell JGynecologic oncology.2011 May 1;21276608
A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system.Martin, Natasha K; Gaffney, Eamonn A; Gatenby, Robert A; Gillies, Robert J; Robey, Ian F; Maini, Philip KMathematical biosciences.2011 Mar;21167185
Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.Kenny, Hilary A; Leonhardt, Payton; Ladanyi, Andras; Yamada, S Diane; Montag, Anthony; Im, Hae Kyung; Jagadeeswaran, Sujatha; Shaw, David E; Mazar, Andrew P; Lengyel, ErnstClinical cancer research : an official journal of the American Association for Cancer Research.2011 Feb 1;21149615
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{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.Kaur, Swayamjot; Kenny, Hilary A; Jagadeeswaran, Sujatha; Zillhardt, Marion R; Montag, Anthony G; Kistner, Emily; Yamada, S Diane; Mitra, Anirban K; Lengyel, ErnstThe American journal of pathology.2009 Nov;19808644
Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis.Kenny, Hilary A; Dogan, Songuel; Zillhardt, Marion; K Mitra, Anirban; Yamada, S Diane; Krausz, Thomas; Lengyel, ErnstCancer treatment and research.2009;19763444
Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.Romero, Iris L; Gordon, Ilyssa O; Jagadeeswaran, Sujatha; Mui, Keeley L; Lee, Woo Seok; Dinulescu, Daniela M; Krausz, Thomas N; Kim, Helen H; Gilliam, Melissa L; Lengyel, ErnstCancer prevention research (Philadelphia, Pa.).2009 Sep;19737983
Metabolomics in the assessment of chemical-induced reproductive and developmental outcomes using non-invasive biological fluids: application to the study of butylbenzyl phthalate.Sumner, Susan; Snyder, Rodney; Burgess, Jason; Myers, Christina; Tyl, Rochelle; Sloan, Carol; Fennell, TimothyJournal of applied toxicology : JAT.2009 Nov;19731247
The molecular signature of endometriosis-associated endometrioid ovarian cancer differs significantly from endometriosis-independent endometrioid ovarian cancer.Banz, Constanze; Ungethuem, Ute; Kuban, Ralf-Juergen; Diedrich, Klaus; Lengyel, Ernst; Hornung, DanielaFertility and sterility.2010 Sep;19643405
Adaptive therapy.Gatenby, Robert A; Silva, Ariosto S; Gillies, Robert J; Frieden, B RoyCancer research.2009 Jun 1;19487300
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein.He, Ling; Sabet, Amin; Djedjos, Stephen; Miller, Ryan; Sun, Xiaojian; Hussain, Mehboob A; Radovick, Sally; Wondisford, Fredric ECell.2009 May 15;19450513
Bicarbonate increases tumor pH and inhibits spontaneous metastases.Robey, Ian F; Baggett, Brenda K; Kirkpatrick, Nathaniel D; Roe, Denise J; Dosescu, Julie; Sloane, Bonnie F; Hashim, Arig Ibrahim; Morse, David L; Raghunand, Natarajan; Gatenby, Robert A; Gillies, Robert JCancer research.2009 Mar 15;19276390
The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion.Silva, Ariosto S; Yunes, Jose A; Gillies, Robert J; Gatenby, Robert ACancer research.2009 Mar 15;19276380
Responsive MRI agents for sensing metabolism in vivo.De Leon-Rodriguez, Luis M; Lubag, Angelo Josue M; Malloy, Craig R; Martinez, Gary V; Gillies, Robert J; Sherry, A DeanAccounts of chemical research.2009 Jul 21;19265438
MMP-2 functions as an early response protein in ovarian cancer metastasis.Kenny, Hilary A; Lengyel, ErnstCell cycle (Georgetown, Tex.).2009 Mar 1;19221481
Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.Morse, David L; Carroll, Danielle; Day, Sam; Gray, Heather; Sadarangani, Pooja; Murthi, Shiva; Job, Constantin; Baggett, Brenda; Raghunand, Natarajan; Gillies, Robert JNMR in biomedicine.2009 Jan;19016452
Does equal treatment yield equal outcomes? The impact of race on survival in epithelial ovarian cancer.Terplan, Mishka; Temkin, Sarah; Tergas, Ana; Lengyel, ErnstGynecologic oncology.2008 Nov;18823649
Regulation of the Warburg effect in early-passage breast cancer cells.Robey, Ian F; Stephen, Renu M; Brown, Kathy S; Baggett, Brenda K; Gatenby, Robert A; Gillies, Robert JNeoplasia (New York, N.Y.).2008 Aug;18670636
Imaging hemodynamics.Jennings, Dominique; Raghunand, Natarajan; Gillies, Robert JCancer metastasis reviews.2008 Dec;18506397
Longitudinal diffusion tensor imaging in a rat brain glioma model.Lope-Piedrafita, Silvia; Garcia-Martin, Maria L; Galons, Jean-Philippe; Gillies, Robert J; Trouard, Theodore PNMR in biomedicine.2008 Oct;18470959
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.Park, Sun-Mi; Gaur, Arti B; Lengyel, Ernst; Peter, Marcus EGenes & development.2008 Apr 1;18381893
Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.Sawada, Kenjiro; Mitra, Anirban K; Radjabi, A Reza; Bhaskar, Vinay; Kistner, Emily O; Tretiakova, Maria; Jagadeeswaran, Sujatha; Montag, Anthony; Becker, Amy; Kenny, Hilary A; Peter, Marcus E; Ramakrishnan, Vanitha; Yamada, S Diane; Lengyel, ErnstCancer research.2008 Apr 1;18381440
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.Kenny, Hilary A; Kaur, Swayamjot; Coussens, Lisa M; Lengyel, ErnstThe Journal of clinical investigation.2008 Apr;18340378
Acid treatment of melanoma cells selects for invasive phenotypes.Moellering, Raymond E; Black, Kvar C; Krishnamurty, Chetan; Baggett, Brenda K; Stafford, Phillip; Rain, Matthew; Gatenby, Robert A; Gillies, Robert JClinical & experimental metastasis.2008;18301995
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.Radjabi, A Reza; Sawada, Kenjiro; Jagadeeswaran, Sujatha; Eichbichler, Alfred; Kenny, Hilary A; Montag, Anthony; Bruno, Katharina; Lengyel, ErnstThe Journal of biological chemistry.2008 Feb 1;18048360
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.Park, Sun-Mi; Shell, Scott; Radjabi, Amir Reza; Schickel, Robert; Feig, Christine; Boyerinas, Ben; Dinulescu, Daniela M; Lengyel, Ernst; Peter, Marcus ECell cycle (Georgetown, Tex.).2007 Nov 1;17957144
DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles.Borden, Mark A; Caskey, Charles F; Little, Erika; Gillies, Robert J; Ferrara, Katherine WLangmuir : the ACS journal of surfaces and colloids.2007 Aug 28;17665937
Response of choline metabolites to docetaxel therapy is quantified in vivo by localized (31)P MRS of human breast cancer xenografts and in vitro by high-resolution (31)P NMR spectroscopy of cell extracts.Morse, David L; Raghunand, Natarajan; Sadarangani, Pooja; Murthi, Shiva; Job, Constantin; Day, Sam; Howison, Christine; Gillies, Robert JMagnetic resonance in medicine.2007 Aug;17654590
Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?Gillies, Robert J; Gatenby, Robert AJournal of bioenergetics and biomembranes.2007 Jun;17624581
Let-7 expression defines two differentiation stages of cancer.Shell, Scott; Park, Sun-Mi; Radjabi, Amir Reza; Schickel, Robert; Kistner, Emily O; Jewell, David A; Feig, Christine; Lengyel, Ernst; Peter, Marcus EProceedings of the National Academy of Sciences of the United States of America.2007 Jul 3;17600087
Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum.Kenny, Hilary A; Krausz, Thomas; Yamada, Seiko D; Lengyel, ErnstInternational journal of cancer.2007 Oct 1;17546601
Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer.Leupold, Jorg H; Asangani, Irfan; Maurer, Gabriele D; Lengyel, Ernst; Post, Stefan; Allgayer, HeikeMolecular cancer research : MCR.2007 May;17510314
Hypoxia and adaptive landscapes in the evolution of carcinogenesis.Gillies, Robert J; Gatenby, Robert ACancer metastasis reviews.2007 Jun;17404691
Tyrosine kinase mutations in human cancer.Lengyel, Ernst; Sawada, Kenjiro; Salgia, RaviCurrent molecular medicine.2007 Feb;17311534
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.Sawada, Kenjiro; Radjabi, A Reza; Shinomiya, Nariyoshi; Kistner, Emily; Kenny, Hilary; Becker, Amy R; Turkyilmaz, Muge A; Salgia, Ravi; Yamada, S Diane; Vande Woude, George F; Tretiakova, Maria S; Lengyel, ErnstCancer research.2007 Feb 15;17308108
MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms.Morse, David L; Galons, Jean-Philippe; Payne, Claire M; Jennings, Dominique L; Day, Sam; Xia, Guowei; Gillies, Robert JNMR in biomedicine.2007 Oct;17265424
Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation.Hussain, Mehboob A; Porras, Delia L; Rowe, Matthew H; West, Jason R; Song, Woo-Jin; Schreiber, Weston E; Wondisford, Fredric EMolecular and cellular biology.2006 Oct;16908541
Lateral phase separation in lipid-coated microbubbles.Borden, Mark A; Martinez, Gary V; Ricker, Josette; Tsvetkova, Nelly; Longo, Marjorie; Gillies, Robert J; Dayton, Paul A; Ferrara, Katherine WLangmuir : the ACS journal of surfaces and colloids.2006 Apr 25;16618177
High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity.Garcia-Martin, Maria L; Martinez, Gary V; Raghunand, Natarajan; Sherry, A Dean; Zhang, Shanrong; Gillies, Robert JMagnetic resonance in medicine.2006 Feb;16402385
Metabolite changes in HT-29 xenograft tumors following HIF-1alpha inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo.Jordan, Benedicte F; Black, Kvar; Robey, Ian F; Runquist, Matthew; Powis, Garth; Gillies, Robert JNMR in biomedicine..2005 Nov;16206237
Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.Robey, Ian F; Lien, Anthony D; Welsh, Sarah J; Baggett, Brenda K; Gillies, Robert JNeoplasia (New York, N.Y.).2005 Apr;15967109
Dynamic contrast-enhanced and diffusion MRI show rapid and dramatic changes in tumor microenvironment in response to inhibition of HIF-1alpha using PX-478.Jordan, Benedicte F; Runquist, Matthew; Raghunand, Natarajan; Baker, Amanda; Williams, Ryan; Kirkpatrick, Lynn; Powis, Garth; Gillies, Robert JNeoplasia (New York, N.Y.).2005 May;15967100
Determining suitable internal standards for mRNA quantification of increasing cancer progression in human breast cells by real-time reverse transcriptase polymerase chain reaction.Morse, David L; Carroll, Danielle; Weberg, Lyndon; Borgstrom, Mark C; Ranger-Moore, James; Gillies, Robert JAnalytical biochemistry..2005 Jul 1;15958182
The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging.Jordan, Benedicte F; Runquist, Matthew; Raghunand, Natarajan; Gillies, Robert J; Tate, Wendy R; Powis, Garth; Baker, Amanda FClinical cancer research : an official journal of the American Association for Cancer Research.2005 Jan 15;15701837
pH imaging. A review of pH measurement methods and applications in cancers.Gillies, Robert J; Raghunand, Natarajan; Garcia-Martin, Maria L; Gatenby, Robert AIEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society..2004 Sep-Oct;15565800
Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein.Zhou, Xiao Yan; Shibusawa, Nobuyuki; Naik, Karuna; Porras, Delia; Temple, Karla; Ou, Hesheng; Kaihara, Kelly; Roe, Michael W; Brady, Matthew J; Wondisford, Fredric ENature medicine..2004 Jun;15146178
Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents.Raghunand, Natarajan; Mahoney, Brent P; Gillies, Robert JBiochemical pharmacology..2003 Oct 1;14505801
Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro.Mahoney, Brent P; Raghunand, Natarajan; Baggett, Brenda; Gillies, Robert JBiochemical pharmacology..2003 Oct 1;14505800
Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors.Schornack, Paul A; Gillies, Robert JNeoplasia (New York, N.Y.).2003 Mar-Apr;12659686
Renal and systemic pH imaging by contrast-enhanced MRI.Raghunand, Natarajan; Howison, Christine; Sherry, A Dean; Zhang, Shanrong; Gillies, Robert JMagnetic resonance in medicine.2003 Feb;12541244
MRI of the tumor microenvironment.Gillies, Robert J; Raghunand, Natarajan; Karczmar, Gregory S; Bhujwalla, Zaver MJournal of magnetic resonance imaging : JMRI..2002 Oct;12353258
In vivo magnetic resonance imaging of tissue pH using a novel pH-sensitive contrast agent, GdDOTA-4AmP.Raghunand, Natarajan; Zhang, Shanrong; Sherry, A Dean; Gillies, Robert JAcademic radiology..2002 Aug;12188315
Combined vascular and extracellular pH imaging of solid tumors.Bhujwalla, Z M; Artemov, D; Ballesteros, P; Cerdan, S; Gillies, R J; Solaiyappan, MNMR in biomedicine..2002 Apr;11870907
Consolidation of extinction learning involves transfer from NMDA-independent to NMDA-dependent memory.Santini, E; Muller, R U; Quirk, G JThe Journal of neuroscience : the official journal of the Society for Neuroscience.2001 Nov 15;11698611
Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone.Raghunand, N; Mahoney, B; van Sluis, R; Baggett, B; Gillies, R JNeoplasia (New York, N.Y.).2001 May-Jun;11494116
Causes and effects of heterogeneous perfusion in tumors.Gillies, R J; Schornack, P A; Secomb, T W; Raghunand, NNeoplasia (New York, N.Y.).1999 Aug;10935474
Applications of magnetic resonance in model systems: tumor biology and physiology.Gillies, R J; Bhujwalla, Z M; Evelhoch, J; Garwood, M; Neeman, M; Robinson, S P; Sotak, C H; Van Der Sanden, BNeoplasia (New York, N.Y.).2000 Jan-Apr;10933073

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