Nanomedicine (651)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Measuring Behavioral Individuality in the Acoustic Startle Behavior in Zebrafish.Pantoja, Carlos; Hoagland, Adam; Carroll, Elizabeth; Schoppik, David; Isacoff, Ehud YBio-protocol.2017 Apr 05;28752108
Sequential Steps of CRAC Channel Activation.Palty, Raz; Fu, Zhu; Isacoff, Ehud YCell reports.2017 May 30;28564609
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors.Levitz, Joshua; Broichhagen, Johannes; Leippe, Philipp; Konrad, David; Trauner, Dirk; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America.2017 Apr 25;28396447
Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.Jarrett, Kelsey E; Lee, Ciaran M; Yeh, Yi-Hsien; Hsu, Rachel H; Gupta, Rajat; Zhang, Min; Rodriguez, Perla J; Lee, Chang Seok; Gillard, Baiba K; Bissig, Karl-Dimiter; Pownall, Henry J; Martin, James F; Bao, Gang; Lagor, William RScientific reports.2017 Mar 16;28300165
Input-Specific Plasticity and Homeostasis at the Drosophila Larval Neuromuscular Junction.Newman, Zachary L; Hoagland, Adam; Aghi, Krishan; Worden, Kurtresha; Levy, Sabrina L; Son, Jun Ho; Lee, Luke P; Isacoff, Ehud YNeuron.2017 Mar 22;28285823
Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO).Barber, David M; Schönberger, Matthias; Burgstaller, Jessica; Levitz, Joshua; Weaver, C David; Isacoff, Ehud Y; Baier, Herwig; Trauner, DirkChemical science.2016;28090283
How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina.Tochitsky, Ivan; Helft, Zachary; Meseguer, Victor; Fletcher, Russell B; Vessey, Kirstan A; Telias, Michael; Denlinger, Bristol; Malis, Jonatan; Fletcher, Erica L; Kramer, Richard HNeuron.2016 Oct 05;27667006
Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.Levitz, Joshua; Habrian, Chris; Bharill, Shashank; Fu, Zhu; Vafabakhsh, Reza; Isacoff, Ehud YNeuron.2016 Oct 05;27641494
A multifunctional AAV-CRISPR-Cas9 and its host response.Chew, Wei Leong; Tabebordbar, Mohammadsharif; Cheng, Jason K W; Mali, Prashant; Wu, Elizabeth Y; Ng, Alex H M; Zhu, Kexian; Wagers, Amy J; Church, George MNature methods.2016 Oct;27595405
Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by NPHP5 mutation.Downs, Louise M; Scott, Erin M; Cideciyan, Artur V; Iwabe, Simone; Dufour, Valerie; Gardiner, Kristin L; Genini, Sem; Marinho, Luis Felipe; Sumaroka, Alexander; Kosyk, Mychajlo S; Swider, Malgorzata; Aguirre, Geoffrey K; Jacobson, Samuel G; Beltran, WilliHuman molecular genetics.2016 Oct 01;27506978
Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.Rowe, R Grant; Wang, Leo D; Coma, Silvia; Han, Areum; Mathieu, Ronald; Pearson, Daniel S; Ross, Samantha; Sousa, Patricia; Nguyen, Phi T; Rodriguez, Antony; Wagers, Amy J; Daley, George QThe Journal of experimental medicine.2016 Jul 25;27401346
Neuromodulatory Regulation of Behavioral Individuality in Zebrafish.Pantoja, Carlos; Hoagland, Adam; Carroll, Elizabeth C; Karalis, Vasiliki; Conner, Alden; Isacoff, Ehud YNeuron.2016 Aug 03;27397519
Treating hemoglobinopathies using gene-correction approaches: promises and challenges.Cottle, Renee N; Lee, Ciaran M; Bao, GangHuman genetics.;27314256
Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand.Broichhagen, Johannes; Damijonaitis, Arunas; Levitz, Joshua; Sokol, Kevin R; Leippe, Philipp; Konrad, David; Isacoff, Ehud Y; Trauner, DirkACS central science.2015 Oct 28;27162996
Assessment of visual function and retinal structure following acute light exposure in the light sensitive T4R rhodopsin mutant dog.Iwabe, Simone; Ying, Gui-Shuang; Aguirre, Gustavo D; Beltran, William AExperimental eye research.2016 May;27085210
A family of photoswitchable NMDA receptors.Berlin, Shai; Szobota, Stephanie; Reiner, Andreas; Carroll, Elizabeth C; Kienzler, Michael A; Guyon, Alice; Xiao, Tong; Trauner, Dirk; Isacoff, Ehud YeLife.2016 Mar 01;26929991
A Toolkit for Orthogonal and in vivo Optical Manipulation of Ionotropic Glutamate Receptors.Levitz, Joshua; Popescu, Andrei T; Reiner, Andreas; Isacoff, Ehud YFrontiers in molecular neuroscience.2016;26869877
Intracellular delivery of molecules using microfabricated nanoneedle arrays.Park, Seonhee; Choi, Seong-O; Paik, Seung-joon; Choi, Seungkeun; Allen, Mark; Prausnitz, MarkBiomedical microdevices.2016 Feb;26797026
The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.Lee, Ciaran M; Cradick, Thomas J; Bao, GangMolecular therapy : the journal of the American Society of Gene Therapy.2016 Mar;26782639
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.Zhao, Guoping; Neely, Aaron M; Schwarzer, Christian; Lu, Huayi; Whitt, Aaron G; Stivers, Nicole S; Burlison, Joseph A; White, Carl; Machen, Terry E; Li, ChiOncotarget.2016 Feb 02;26758417
In vivo gene editing in dystrophic mouse muscle and muscle stem cells.Tabebordbar, Mohammadsharif; Zhu, Kexian; Cheng, Jason K W; Chew, Wei Leong; Widrick, Jeffrey J; Yan, Winston X; Maesner, Claire; Wu, Elizabeth Y; Xiao, Ru; Ran, F Ann; Cong, Le; Zhang, Feng; Vandenberghe, Luk H; Church, George M; Wagers, Amy JScience (New York, N.Y.).2016 Jan 22;407-1126721686
Towards a new era in medicine: therapeutic genome editing.Porteus, Matthew HGenome biology.2015;26694713
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.Müller, Maximilian; Lee, Ciaran M; Gasiunas, Giedrius; Davis, Timothy H; Cradick, Thomas J; Siksnys, Virginijus; Bao, Gang; Cathomen, Toni; Mussolino, ClaudioMolecular therapy : the journal of the American Society of Gene Therapy.2016 Mar;26658966
Lateral Inhibition in the Vertebrate Retina: The Case of the Missing Neurotransmitter.Kramer, Richard H; Davenport, Christopher MPLoS biology.2015 Dec;26656622
A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA(A) Receptors and Synaptic Inhibition.Lin, Wan-Chen; Tsai, Ming-Chi; Davenport, Christopher M; Smith, Caleb M; Veit, Julia; Wilson, Neil M; Adesnik, Hillel; Kramer, Richard HNeuron.2015 Dec 02;26606997
Genome Editing: A New Approach to Human Therapeutics.Porteus, MatthewAnnual review of pharmacology and toxicology.2016;26566154
Controlled delivery of ?-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection.Cottle, Renee N; Lee, Ciaran M; Archer, David; Bao, GangScientific reports.2015;26558999
Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus.Miju?kovi?, Martina; Chou, Yi-Fan; Gigi, Vered; Lindsay, Cory R; Shestova, Olga; Lewis, Susanna M; Roth, David BCell reports.2015 Sep 22;26365182
Conformational dynamics of a class C G-protein-coupled receptor.Vafabakhsh, Reza; Levitz, Joshua; Isacoff, Ehud YNature.2015 Aug 27;26258295
Physical Principles of Nanoparticle Cellular Endocytosis.Zhang, Sulin; Gao, Huajian; Bao, GangACS nano.2015 Sep 22;26256227
AAV ancestral reconstruction library enables selection of broadly infectious viral variants.Santiago-Ortiz, J; Ojala, D S; Westesson, O; Weinstein, J R; Wong, S Y; Steinsapir, A; Kumar, S; Holmes, I; Schaffer, D VGene therapy.2015 Dec;26186661
Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging.Berlin, Shai; Carroll, Elizabeth C; Newman, Zachary L; Okada, Hitomi O; Quinn, Carson M; Kallman, Benjamin; Rockwell, Nathan C; Martin, Shelley S; Lagarias, J Clark; Isacoff, Ehud YNature methods.2015 Sep;26167640
IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system.Spitzer, Matthew H; Gherardini, Pier Federico; Fragiadakis, Gabriela K; Bhattacharya, Nupur; Yuan, Robert T; Hotson, Andrew N; Finck, Rachel; Carmi, Yaron; Zunder, Eli R; Fantl, Wendy J; Bendall, Sean C; Engleman, Edgar G; Nolan, Garry PScience (New York, N.Y.).2015 Jul 10;26160952
Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity.Gaub, Benjamin M; Berry, Michael H; Holt, Amy E; Isacoff, Ehud Y; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy.2015 Oct;26137852
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.Hendel, Ayal; Bak, Rasmus O; Clark, Joseph T; Kennedy, Andrew B; Ryan, Daniel E; Roy, Subhadeep; Steinfeld, Israel; Lunstad, Benjamin D; Kaiser, Robert J; Wilkens, Alec B; Bacchetta, Rosa; Tsalenko, Anya; Dellinger, Douglas; Bruhn, Laurakay; Porteus, MattNature biotechnology.2015 Sep;26121415
Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles.Sengupta, Aritra; Mezencev, Roman; McDonald, John F; Prausnitz, Mark RNanomedicine (London, England).2015;26080699
Genome Editing of the Blood: Opportunities and Challenges.Porteus, Matthew HCurrent stem cell reports.2015 Mar 1;26029496
Drug delivery: Puncturing cells en masse.Prausnitz, Mark RNature materials.2015 May;25899907
Optopharmacological tools for restoring visual function in degenerative retinal diseases.Tochitsky, Ivan; Kramer, Richard HCurrent opinion in neurobiology.2015 Oct;25706312
Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.Marsili, Stefania; Genini, Sem; Sudharsan, Raghavi; Gingrich, Jeremy; Aguirre, Gustavo D; Beltran, William APloS one.2015;25695253
Codon swapping of zinc finger nucleases confers expression in primary cells and in vivo from a single lentiviral vector.Abarrategui-Pontes, Cécilia; Créneguy, Alison; Thinard, Reynald; Fine, Eli J; Thepenier, Virginie; Fournier, Le Ray Laure; Cradick, Thomas J; Bao, Gang; Tesson, Laurent; Podevin, Guillaume; Anegon, Ignacio; Nguyen, T HuyCurrent gene therapy.2014;25687502
Photochemical approaches to vision restoration.Van Gelder, Russell NVision research.2015 Jun;25680758
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics.Carroll, Elizabeth C; Berlin, Shai; Levitz, Joshua; Kienzler, Michael A; Yuan, Zhe; Madsen, Dorte; Larsen, Delmar S; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America.2015 Feb 17;25653339
Single-cell detection of mRNA expression using nanofountain-probe electroporated molecular beacons.Giraldo-Vela, Juan P; Kang, Wonmo; McNaughton, Rebecca L; Zhang, Xuemei; Wile, Brian M; Tsourkas, Andrew; Bao, Gang; Espinosa, Horacio DSmall (Weinheim an der Bergstrasse, Germany).2015 May;25641752
Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.Schwarzer, Christian; Fu, Zhu; Morita, Takeshi; Whitt, Aaron G; Neely, Aaron M; Li, Chi; Machen, Terry EThe Journal of biological chemistry.2015 Mar 13;25627690
Quantifying on- and off-target genome editing.Hendel, Ayal; Fine, Eli J; Bao, Gang; Porteus, Matthew HTrends in biotechnology.2015 Feb;25595557
Controlling ionotropic and metabotropic glutamate receptors with light: principles and potential.Reiner, Andreas; Levitz, Joshua; Isacoff, Ehud YCurrent opinion in pharmacology.2015 Feb;25573450
A spinal opsin controls early neural activity and drives a behavioral light response.Friedmann, Drew; Hoagland, Adam; Berlin, Shai; Isacoff, Ehud YCurrent biology : CB.2015 Jan 5;25484291
Live-cell mass profiling: an emerging approach in quantitative biophysics.Zangle, Thomas A; Teitell, Michael ANature methods.2014 Dec;25423019
Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.Byrne, Leah C; Dalkara, Deniz; Luna, Gabriel; Fisher, Steven K; Clérin, Emmanuelle; Sahel, Jose-Alain; Léveillard, Thierry; Flannery, John GThe Journal of clinical investigation.2015 Jan;25415434
Visualizing mammalian brain area interactions by dual-axis two-photon calcium imaging.Lecoq, Jérôme; Savall, Joan; Vu?ini?, Dejan; Grewe, Benjamin F; Kim, Hyun; Li, Jin Zhong; Kitch, Lacey J; Schnitzer, Mark JNature neuroscience.2014 Dec;25402858
Simplified prototyping of perfusable polystyrene microfluidics.Tran, Reginald; Ahn, Byungwook; Myers, David R; Qiu, Yongzhi; Sakurai, Yumiko; Moot, Robert; Mihevc, Emma; Trent Spencer, H; Doering, Christopher; A Lam, WilburBiomicrofluidics.2014 Jul;25379106
Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation.Qiu, Yongzhi; Brown, Ashley C; Myers, David R; Sakurai, Yumiko; Mannino, Robert G; Tran, Reginald; Ahn, Byungwook; Hardy, Elaissa T; Kee, Matthew F; Kumar, Sanjay; Bao, Gang; Barker, Thomas H; Lam, Wilbur AProceedings of the National Academy of Sciences of the United States of America.2014 Oct 7;25246564
The expression pattern of systemically injected AAV9 in the developing mouse retina is determined by age.Byrne, Leah C; Lin, Yvonne J; Lee, Trevor; Schaffer, David V; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy.2015 Feb;25224467
Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid.Comoglio, Yannick; Levitz, Joshua; Kienzler, Michael A; Lesage, Florian; Isacoff, Ehud Y; Sandoz, GuillaumeProceedings of the National Academy of Sciences of the United States of America.2014 Sep 16;25197053
Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells.Sengupta, Aritra; Dwivedi, Nishant; Kelly, Sean C; Tucci, Lara; Thadhani, Naresh N; Prausnitz, Mark RBiotechnology and bioengineering.2015 Feb;25182778
Single-cell mass cytometry analysis of human tonsil T cell remodeling by varicella zoster virus.Sen, Nandini; Mukherjee, Gourab; Sen, Adrish; Bendall, Sean C; Sung, Phillip; Nolan, Garry P; Arvin, Ann MCell reports.2014 Jul 24;25043183
Autophagy mediates HIF2* degradation and suppresses renal tumorigenesis.Liu, X-D; Yao, J; Tripathi, D N; Ding, Z; Xu, Y; Sun, M; Zhang, J; Bai, S; German, P; Hoang, A; Zhou, L; Jonasch, D; Zhang, X; Conti, C J; Efstathiou, E; Tannir, N M; Eissa, N T; Mills, G B; Walker, C L; Jonasch, EOncogene2014 Jul 7NULL24998849
Automated identification of stratifying signatures in cellular subpopulations.Bruggner, Robert V; Bodenmiller, Bernd; Dill, David L; Tibshirani, Robert J; Nolan, Garry PProceedings of the National Academy of Sciences of the United States of America2014 Jul 1E2770-724979804
Rational design of topographical helix mimics as potent inhibitors of protein-protein interactions.Lao, Brooke Bullock; Drew, Kevin; Guarracino, Danielle A; Brewer, Thomas F; Heindel, Daniel W; Bonneau, Richard; Arora, Paramjit SJournal of the American Chemical Society2014 Jun 47877-8824972345
An application of a Hill-based response surface model for a drug combination experiment on lung cancer.Ning, Shaoyang; Xu, Hongquan; Al-Shyoukh, Ibrahim; Feng, Jiaying; Sun, RenStatistics in medicine.2014 Oct 30;24942112
Negative example selection for protein function prediction: the NoGO database.Youngs, Noah; Penfold-Brown, Duncan; Bonneau, Richard; Shasha, DennisPLoS computational biology2014 June100364424922051
Use of cell morphology as early bioindicator for viral infection.Ding, Xianting; Liu, Ningxia; Matsuo, Kyle; Sun, Mingzhu; Zhao, XinIET nanobiotechnology / IET2014 Mar24-3024888188
Type three secretion system-mediated escape of Burkholderia pseudomallei into the host cytosol is critical for the activation of NF*B.Teh, Boon Eng; French, Christopher Todd; Chen, Yahua; Chen, Isabelle Gek Joo; Wu, Ting-Hsiang; Sagullo, Enrico; Chiou, Pei-Yu; Teitell, Michael A; Miller, Jeff F; Gan, Yunn-HwenBMC microbiology201411524884837
Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.Bakthavatsalam, Deenadayalan; Soung, Roh Hun; Tweardy, David J; Chiu, Wah; Dixon, Richard A F; Woodside, Darren GFEBS letters2014 Jun 132133-4024846140
CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.Lin, Yanni; Cradick, Thomas J; Brown, Matthew T; Deshmukh, Harshavardhan; Ranjan, Piyush; Sarode, Neha; Wile, Brian M; Vertino, Paula M; Stewart, Frank J; Bao, GangNucleic acids research20147473-8524838573
A rotamer library to enable modeling and design of peptoid foldamers.Renfrew, P Douglas; Craven, Timothy W; Butterfoss, Glenn L; Kirshenbaum, Kent; Bonneau, RichardJournal of the American Chemical Society2014 Jun 188772-8224823488
Engineering a light-regulated GABAA receptor for optical control of neural inhibition.Lin, Wan-Chen; Davenport, Christopher M; Mourot, Alexandre; Vytla, Devaiah; Smith, Caleb M; Medeiros, Kathryne A; Chambers, James J; Kramer, Richard HACS chemical biology2014 Jul 181414-924819442
TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.Mussolino, Claudio; Alzubi, Jamal; Fine, Eli J; Morbitzer, Robert; Cradick, Thomas J; Lahaye, Thomas; Bao, Gang; Cathomen, ToniNucleic acids research20146762-7324792154
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.Bendall, Sean C; Davis, Kara L; Amir, El-Ad David; Tadmor, Michelle D; Simonds, Erin F; Chen, Tiffany J; Shenfeld, Daniel K; Nolan, Garry P; Pe'er, DanaCell2014 Apr 24714-2524766814
Modulation of STAT3 folding and function by TRiC/CCT chaperonin.Kasembeli, Moses; Lau, Wilson Chun Yu; Roh, Soung-Hun; Eckols, T Kris; Frydman, Judith; Chiu, Wah; Tweardy, David JPLoS biology2014 Apre100184424756126
Genetic and Pharmacological Strategies to Refunctionalize the von Hippel Lindau R167Q Mutant Protein.Ding, Zhiyong; German, Peter; Bai, Shanshan; Reddy, A Srinivas; Liu, Xian-De; Sun, Mianen; Zhou, Lijun; Chen, Xiaohua; Zhao, Xiaobei; Wu, Chengbiao; Zhang, Shuxing; Mills, Gordon B; Jonasch, EricCancer research2014 Apr 22NULL24755468
Stoichiometry and specific assembly of Best ion channels.Bharill, Shashank; Fu, Zhu; Palty, Raz; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America2014 Apr 296491-624748110
Photoswitching of cell surface receptors using tethered ligands.Reiner, Andreas; Isacoff, Ehud YMethods in molecular biology (Clifton, N.J.)201445-6824718794
Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.Park, Jason S; Rhau, Benjamin; Hermann, Aynur; McNally, Krista A; Zhou, Carmen; Gong, Delquin; Weiner, Orion D; Conklin, Bruce R; Onuffer, James; Lim, Wendell AProceedings of the National Academy of Sciences of the United States of America2014 Apr 225896-90124711398
Retinoschisin gene therapy in photoreceptors, Muller glia or all retinal cells in the Rs1h-/- mouse.Byrne, L C; Ozturk, B E; Lee, T; Fortuny, C; Visel, M; Dalkara, D; Schaffer, D V; Flannery, J GGene therapy2014 Apr 3NULL24694538
Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing.Hendel, Ayal; Kildebeck, Eric J; Fine, Eli J; Clark, Joseph T; Punjya, Niraj; Sebastiano, Vittorio; Bao, Gang; Porteus, Matthew HCell reports2014 Apr 10293-30524685129
A molecular interpretation of 2D IR protein folding experiments with Markov state models.Baiz, Carlos R; Lin, Yu-Shan; Peng, Chunte Sam; Beauchamp, Kyle A; Voelz, Vincent A; Pande, Vijay S; Tokmakoff, AndreiBiophysical journal2014 Mar 181359-7024655511
Group II archaeal chaperonin recognition of partially folded human ýýD-crystallin mutants.Sergeeva, Oksana A; Yang, Jingkun; King, Jonathan A; Knee, Kelly MProtein science : a publication of the Protein Society2014 Mar 10NULL24615724
Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.Schwarzer, Christian; Ravishankar, Bharat; Patanwala, Maria; Shuai, Stacey; Fu, Zhu; Illek, Beate; Fischer, Horst; Machen, Terry EAmerican journal of physiology. Cell physiology2014 May 1C844-5524598360
Multiplexed ion beam imaging of human breast tumors.Angelo, Michael; Bendall, Sean C; Finck, Rachel; Hale, Matthew B; Hitzman, Chuck; Borowsky, Alexander D; Levenson, Richard M; Lowe, John B; Liu, Scot D; Zhao, Shuchun; Natkunam, Yasodha; Nolan, Garry PNature medicine2014 Apr436-4224584119
Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography.Shahmoradian, Sarah H; Galiano, Mauricio R; Wu, Chengbiao; Chen, Shurui; Rasband, Matthew N; Mobley, William C; Chiu, WahJournal of visualized experiments : JoVE2014e5078324561719
Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy.Reiner, Andreas; Isacoff, Ehud YNature chemical biology2014 Apr273-8024561661
Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells.Tochitsky, Ivan; Polosukhina, Aleksandra; Degtyar, Vadim E; Gallerani, Nicholas; Smith, Caleb M; Friedman, Aaron; Van Gelder, Russell N; Trauner, Dirk; Kaufer, Daniela; Kramer, Richard HNeuron2014 Feb 19800-1324559673
Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.Fine, Eli J; Cradick, Thomas J; Bao, GangMethods in molecular biology (Clifton, N.J.)2014371-8324557916
An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases.Lindsay, Cory R; Roth, David BMethods in molecular biology (Clifton, N.J.)2014353-6924557915
Designing and testing the activities of TAL effector nucleases.Lin, Yanni; Cradick, Thomas J; Bao, GangMethods in molecular biology (Clifton, N.J.)2014203-1924557905
Adeno-associated virus vectors and neurological gene therapy.Ojala, David S; Amara, Dominic P; Schaffer, David VThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.2015 Feb;24557878
Frontiers in bioengineering research.Bao, Gang; Nerem, Robert MAnnals of biomedical engineering.2014 Feb;24510229
Secreting and sensing the same molecule allows cells to achieve versatile social behaviors.Youk, Hyun; Lim, Wendell AScience (New York, N.Y.)2014 Feb 7124278224503857
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.Choudhuri, Kaushik; Llodra, Jaime; Roth, Eric W; Tsai, Jones; Gordo, Susana; Wucherpfennig, Kai W; Kam, Lance C; Stokes, David L; Dustin, Michael LNature2014 Mar 6118-2324487619
Micropatterned, multicomponent supported lipid bilayers for cellular systems.Dutta, Debjit; Kam, Lance CMethods in cell biology201453-6724484657
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.Zhang, Xian; Moore, Simon W; Iskratsch, Thomas; Sheetz, Michael PJournal of cell science2014 Apr 11394-40524481817
CD28 and CD3 have complementary roles in T-cell traction forces.Bashour, Keenan T; Gondarenko, Alexander; Chen, Haoqian; Shen, Keyue; Liu, Xin; Huse, Morgan; Hone, James C; Kam, Lance CProceedings of the National Academy of Sciences of the United States of America2014 Feb 112241-624469820
SAPTA: a new design tool for improving TALE nuclease activity.Lin, Yanni; Fine, Eli J; Zheng, Zhilan; Antico, Christopher J; Voit, Richard A; Porteus, Matthew H; Cradick, Thomas J; Bao, GangNucleic acids research2014 Apre4724442582
Pseudomonas aeruginosa Homoserine Lactone Triggers Apoptosis and Bak/Bax-Independent Release of Mitochondrial Cytochrome C in Fibroblasts.Schwarzer, Christian; Fu, Zhu; Shuai, Stacey; Babbar, Salil; Zhao, Guoping; Li, Chi; Machen, Terry ECellular microbiology2014 Jan 20NULL24438098
Local plasticity of dendritic excitability can be autonomous of synaptic plasticity and regulated by activity-based phosphorylation of Kv4.2.Labno, Anna; Warrier, Ajithkumar; Wang, Sheng; Zhang, XiangPloS one2014e8408624404150
An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.Fine, Eli J; Cradick, Thomas J; Zhao, Charles L; Lin, Yanni; Bao, GangNucleic acids research2014 Apre4224381193
Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility.Bashour, Keenan T; Tsai, Jones; Shen, Keyue; Lee, Joung-Hyun; Sun, Eileen; Milone, Michael C; Dustin, Michael L; Kam, Lance CMolecular and cellular biology2014 Mar955-6424379441
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration.Iskratsch, Thomas; Yu, Cheng-Han; Mathur, Anurag; Liu, Shuaimin; Stevenin, Virginie; Dwyer, Joseph; Hone, James; Ehler, Elisabeth; Sheetz, MichaelDevelopmental cell2013 Dec 9545-5924331927
Focal damage to macaque photoreceptors produces persistent visual loss.Strazzeri, Jennifer M; Hunter, Jennifer J; Masella, Benjamin D; Yin, Lu; Fischer, William S; DiLoreto Jr, David A; Libby, Richard T; Williams, David R; Merigan, William HExperimental eye research2014 Feb88-9624316158
Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Toettcher, Jared E; Weiner, Orion D; Lim, Wendell ACell2013 Dec 51422-3424315106
Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control.Honda, Yoshitomo; Ding, Xianting; Mussano, Federico; Wiberg, Akira; Ho, Chih-Ming; Nishimura, IchiroScientific reports2013342024305548
Nanomedicine: tiny particles and machines give huge gains.Tong, Sheng; Fine, Eli J; Lin, Yanni; Cradick, Thomas J; Bao, GangAnnals of biomedical engineering2014 Feb243-5924297494
Reprogramming an ATP-driven protein machine into a light-gated nanocage.Hoersch, Daniel; Roh, Soung-Hun; Chiu, Wah; Kortemme, TanjaNature nanotechnology2013 Dec928-3224270642
Modeling of proteins and their assemblies with the Integrative Modeling Platform.Webb, Benjamin; Lasker, Keren; Velazquez-Muriel, Javier; Schneidman-Duhovny, Dina; Pellarin, Riccardo; Bonomi, Massimiliano; Greenberg, Charles; Raveh, Barak; Tjioe, Elina; Russel, Daniel; Sali, AndrejMethods in molecular biology (Clifton, N.J.)2014277-9524203340
A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor.Kienzler, Michael A; Reiner, Andreas; Trautman, Eric; Yoo, Stan; Trauner, Dirk; Isacoff, Ehud YJournal of the American Chemical Society2013 Nov 2717683-624171511
Nuclease-mediated gene editing by homologous recombination of the human globin locus.Voit, Richard A; Hendel, Ayal; Pruett-Miller, Shondra M; Porteus, Matthew HNucleic acids research2014 Jan1365-7824157834
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Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies.Russel, Daniel; Lasker, Keren; Webb, Ben; Velazquez-Muriel, Javier; Tjioe, Elina; Schneidman-Duhovny, Dina; Peterson, Bret; Sali, AndrejPLoS biology2012 Jane100124422272186
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In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology.Tsai, Michelle; Kita, Ashley; Leach, Joseph; Rounsevell, Ross; Huang, James N; Moake, Joel; Ware, Russell E; Fletcher, Daniel A; Lam, Wilbur AThe Journal of clinical investigation2012 Jan 3408-1822156199
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Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme.Wei, Fang; Bai, Bin; Ho, Chih-MingBiosensors & bioelectronics2011 Dec 15174-921993141
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE.Qiu, Peng; Simonds, Erin F; Bendall, Sean C; Gibbs Jr, Kenneth D; Bruggner, Robert V; Linderman, Michael D; Sachs, Karen; Nolan, Garry P; Plevritis, Sylvia KNature biotechnology2011 Oct886-9121964415
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A novel method for producing mono-biotinylated, biologically active neurotrophic factors: an essential reagent for single molecule study of axonal transport.Sung, Kijung; Maloney, Michael T; Yang, Jingkun; Wu, ChengbiaoJournal of neuroscience methods2011 Sep 15121-821756937
Sub-diffraction imaging of huntingtin protein aggregates by fluorescence blink-microscopy and atomic force microscopy.Duim, Whitney C; Chen, Bryan; Frydman, Judith; Moerner, W EChemphyschem : a European journal of chemical physics and physical chemistry2011 Sep 122387-9021735512
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Practical performance evaluation of a 10k ýý 10k CCD for electron cryo-microscopy.Bammes, Benjamin E; Rochat, Ryan H; Jakana, Joanita; Chiu, WahJournal of structural biology2011 Sep384-9321619932
Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles.Ashley, Carlee E; Carnes, Eric C; Phillips, Genevieve K; Durfee, Paul N; Buley, Mekensey D; Lino, Christopher A; Padilla, David P; Phillips, Brandy; Carter, Mark B; Willman, Cheryl L; Brinker, C Jeffrey; Caldeira, Jerri do Carmo; Chackerian, Bryce; WhartoACS nano2011 Jul 265729-4521615170
LiGluR restores visual responses in rodent models of inherited blindness.Caporale, Natalia; Kolstad, Kathleen D; Lee, Trevor; Tochitsky, Ivan; Dalkara, Deniz; Trauner, Dirk; Kramer, Richard; Dan, Yang; Isacoff, Ehud Y; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2011 Jul1212-921610698
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Tricontinuous Cubic Nanostructure and Pore Size Patterning in Mesostructured Silica Films Templated with Glycerol Monooleate.Dunphy, Darren R; Garcia, Fred L; Kaehr, Bryan; Khripin, Constantine Y; Collord, Andrew D; Baca, Helen K; Tate, Michael P; Hillhouse, Hugh W; Strzalka, Joseph W; Jiang, Zhang; Wang, Jin; Brinker, C JeffreyChemistry of materials : a publication of the American Chemical Society2011 Apr 262107-211221572556
Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.Zhang, Junjie; Ma, Boxue; DiMaio, Frank; Douglas, Nicholai R; Joachimiak, Lukasz A; Baker, David; Frydman, Judith; Levitt, Michael; Chiu, WahStructure (London, England : 1993)2011 May 11633-921565698
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Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.Bendall, Sean C; Simonds, Erin F; Qiu, Peng; Amir, El-ad D; Krutzik, Peter O; Finck, Rachel; Bruggner, Robert V; Melamed, Rachel; Trejo, Angelica; Ornatsky, Olga I; Balderas, Robert S; Plevritis, Sylvia K; Sachs, Karen; Pe'er, Dana; Tanner, Scott D; NolanScience (New York, N.Y.)2011 May 6687-9621551058
Scaffold proteins: hubs for controlling the flow of cellular information.Good, Matthew C; Zalatan, Jesse G; Lim, Wendell AScience (New York, N.Y.)2011 May 6680-621551057
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.Meiler, Steffen E; Wade, Marlene; Kutlar, Ferdane; Yerigenahally, Shobha D; Xue, Yongjun; Moutouh-de Parseval, Laure A; Corral, Laura G; Swerdlow, Paul S; Kutlar, AbdullahBlood2011 Jul 281109-1221536862
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AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa.Dalkara, Deniz; Kolstad, Kathleen D; Guerin, Karen I; Hoffmann, Natalie V; Visel, Meike; Klimczak, Ryan R; Schaffer, David V; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2011 Sep1602-821522134
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Lipid bilayer coated Al(2)O(3) nanopore sensors: towards a hybrid biological solid-state nanopore.Venkatesan, Bala Murali; Polans, James; Comer, Jeffrey; Sridhar, Supriya; Wendell, David; Aksimentiev, Aleksei; Bashir, RashidBiomedical microdevices2011 Aug671-8221487665
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Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons.Peled, Einat S; Isacoff, Ehud YNature neuroscience2011 Apr519-2621378971
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Translating the lessons from gene therapy to the development of regenerative medicine.Porteus, MatthewMolecular therapy : the journal of the American Society of Gene Therapy2011 Mar439-4121358706
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Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells.Shu, Yi; Cinier, Mathieu; Shu, Dan; Guo, PeixuanMethods (San Diego, Calif.)2011 Jun204-1421320601
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Intravitreal injection of AAV2 transduces macaque inner retina.Yin, Lu; Greenberg, Kenneth; Hunter, Jennifer J; Dalkara, Deniz; Kolstad, Kathleen D; Masella, Benjamin D; Wolfe, Robert; Visel, Meike; Stone, Daniel; Libby, Richard T; Diloreto Jr, David; Schaffer, David; Flannery, John; Williams, David R; Merigan, WilliInvestigative ophthalmology & visual science2011 Apr2775-8321310920
High-speed droplet generation on demand driven by pulse laser-induced cavitation.Park, Sung-Yong; Wu, Ting-Hsiang; Chen, Yue; Teitell, Michael A; Chiou, Pei-YuLab on a chip2011 Mar 211010-221290045
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Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis.Li, S Kevin; Liddell, Mark R; Wen, HeJournal of pharmaceutical and biomedical analysis2011 Jun 1603-721269789
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells.Tsutsui, Hideaki; Valamehr, Bahram; Hindoyan, Antreas; Qiao, Rong; Ding, Xianting; Guo, Shuling; Witte, Owen N; Liu, Xin; Ho, Chih-Ming; Wu, HongNature communications2011 Jan 2516721266967
Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition.Zhou, Jiehua; Shu, Yi; Guo, Peixuan; Smith, David D; Rossi, John JMethods (San Diego, Calif.)2011 Jun284-9421256218
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Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus.Chen, Dong-Hua; Baker, Matthew L; Hryc, Corey F; DiMaio, Frank; Jakana, Joanita; Wu, Weimin; Dougherty, Matthew; Haase-Pettingell, Cameron; Schmid, Michael F; Jiang, Wen; Baker, David; King, Jonathan A; Chiu, WahProceedings of the National Academy of Sciences of the United States of America2011 Jan 251355-6021220301
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Construction of a genetic multiplexer to toggle between chemosensory pathways in Escherichia coli.Moon, Tae Seok; Clarke, Elizabeth J; Groban, Eli S; Tamsir, Alvin; Clark, Ryan M; Eames, Matthew; Kortemme, Tanja; Voigt, Christopher AJournal of molecular biology2011 Feb 18215-2721185306
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Optimized method for the synthesis and purification of adenosine--folic acid conjugates for use as transcription initiators in the preparation of modified RNA.Laing, Brian M; Guo, Peixuan; Bergstrom, Donald EMethods (San Diego, Calif.)2011 Jun260-621163352
Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells.Ha, Kyungsoo; Takeda, Yoshihiko; Dynan, William SDNA repair2011 Mar 7252-921144806
Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange.Smith, Andrew M; Nie, ShumingJournal of the American Chemical Society2011 Jan 1224-621142154
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Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells.Hoffmann, Sabrina; Hosseini, Babak H; Hecker, Markus; Louban, Ilia; Bulbuc, Nadja; Garbi, Natalio; Wabnitz, Guido H; Samstag, Yvonne; Spatz, Joachim P; Hammerling, Gunter JImmunology letters2011 Apr 3013-2021112354
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Integrative systems control approach for reactivating Kaposi's sarcoma-associated herpesvirus (KSHV) with combinatory drugs.Sun, Chien-Pin; Usui, Takane; Yu, Fuqu; Al-Shyoukh, Ibrahim; Shamma, Jeff; Sun, Ren; Ho, Chih-MingIntegrative biology : quantitative biosciences from nano to macro2009 Jan123-3019851479
Dependence of macroscopic wetting on nanoscopic surface textures.Wong, Tak-Sing; Ho, Chih-MingLangmuir : the ACS journal of surfaces and colloids2009 Nov 1712851-419842620
New photochemical tools for controlling neuronal activity.Kramer, Richard H; Fortin, Doris L; Trauner, DirkCurrent opinion in neurobiology2009 Oct544-5219828309
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Hardware-based anti-Brownian electrokinetic trap (ABEL trap) for single molecules: Control loop simulations and application to ATP binding stoichiometry in multi-subunit enzymes.Jiang, Yan; Wang, Quan; Cohen, Adam E; Douglas, Nick; Frydman, Judith; Moerner, W EProceedings - Society of Photo-Optical Instrumentation Engineers2008 Aug 2912-Jan19823693
Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy.Hosseini, Babak H; Louban, Ilia; Djandji, Dominik; Wabnitz, Guido H; Deeg, Janosch; Bulbuc, Nadja; Samstag, Yvonne; Gunzer, Matthias; Spatz, Joachim P; Hammerling, Gunter JProceedings of the National Academy of Sciences of the United States of America2009 Oct 2017852-719822763
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Optical control of zebrafish behavior with halorhodopsin.Arrenberg, Aristides B; Del Bene, Filippo; Baier, HerwigProceedings of the National Academy of Sciences of the United States of America2009 Oct 2017968-7319805086
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Fabrication of Nanoscale Bioarrays for the Study of Cytoskeletal Protein Binding Interactions Using Nanoimprint Lithography.Schvartzman, M; Nguyen, K; Palma, M; Abramson, J; Sable, J; Hone, J; Sheetz, M P; Wind, S JJournal of vacuum science & technology. B, Microelectronics and nanometer structures : processing, measurement, and phenomena : an official journal of the American Vacuum Society2009 Jan 161-6519777075
Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation.Ranzinger, Julia; Krippner-Heidenreich, Anja; Haraszti, Tamas; Bock, Eva; Tepperink, Jessica; Spatz, Joachim P; Scheurich, PeterNano letters2009 Dec4240-519772290
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Engineering the Salmonella type III secretion system to export spider silk monomers.Widmaier, Daniel M; Tullman-Ercek, Danielle; Mirsky, Ethan A; Hill, Rena; Govindarajan, Sridhar; Minshull, Jeremy; Voigt, Christopher AMolecular systems biology200930919756048
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Engineering of the fluorescent-energy-conversion arm of phi29 DNA packaging motor for single-molecule studies.Lee, Tae Jin; Zhang, Hui; Chang, Chun-Li; Savran, Cagri; Guo, PeixuanSmall (Weinheim an der Bergstrasse, Germany)2009 Nov2453-919743427
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Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress.Balatoni, Cynthia E; Dawson, David W; Suh, Jane; Sherman, Mara H; Sanders, Grant; Hong, Jason S; Frank, Matthew J; Malone, Cindy S; Said, Jonathan W; Teitell, Michael AThe American journal of pathology2009 Oct1653-6119717643
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Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.Vasiliver-Shamis, Gaia; Cho, Michael W; Hioe, Catarina E; Dustin, Michael LJournal of virology2009 Nov11341-5519710135
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Exploiting fluorescence resonance energy transfer to probe structural changes in a macromolecule during adsorption and incorporation into a growing biomineral crystal.Touryan, Lara A; Baneyx, Gretchen; Vogel, ViolaColloids and surfaces. B, Biointerfaces2009 Dec 1401-919699065
Strain-dependent photoluminescence behavior of CdSe/CdS nanocrystals with spherical, linear, and branched topologies.Choi, Charina L; Koski, Kristie J; Sivasankar, Sanjeevi; Alivisatos, A PaulNano letters2009 Oct3544-919678687
Biology under construction: in vitro reconstitution of cellular function.Liu, Allen P; Fletcher, Daniel ANature reviews. Molecular cell biology2009 Sep644-5019672276
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.Dalkara, Deniz; Kolstad, Kathleen D; Caporale, Natalia; Visel, Meike; Klimczak, Ryan R; Schaffer, David V; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2009 Dec2096-10219672248
Next-generation quantum dots.Smith, Andrew M; Nie, ShumingNature biotechnology2009 Aug732-319668181
Tat peptide is capable of importing large nanoparticles across nuclear membrane in digitonin permeabilized cells.Nitin, Nitin; LaConte, Leslie; Rhee, Won Jong; Bao, GangAnnals of biomedical engineering2009 Oct2018-2719657743
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome.Forster, Friedrich; Lasker, Keren; Beck, Florian; Nickell, Stephan; Sali, Andrej; Baumeister, WolfgangBiochemical and biophysical research communications2009 Oct 16228-3319653995
In vivo brain imaging using a portable 2.9 g two-photon microscope based on a microelectromechanical systems scanning mirror.Piyawattanametha, Wibool; Cocker, Eric D; Burns, Laurie D; Barretto, Robert P; Jung, Juergen C; Ra, Hyejun; Solgaard, Olav; Schnitzer, Mark JOptics letters2009 Aug 12309-1119649080
Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling.Mandell, Daniel J; Coutsias, Evangelos A; Kortemme, TanjaNature methods2009 Aug551-219644455
Adjustable ellipsoid nanoparticles assembled from re-engineered connectors of the bacteriophage phi29 DNA packaging motor.Xiao, Feng; Cai, Ying; Wang, Joseph Che-Yen; Green, Dominik; Cheng, R Holland; Demeler, Borries; Guo, PeixuanACS nano2009 Aug 252163-7019634910
Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications.Li, Shuyi; Nguyen, Lynsa; Xiong, Hairong; Wang, Meiyao; Hu, Tom C-C; She, Jin-Xiong; Serkiz, Steven M; Wicks, George G; Dynan, William SNanomedicine : nanotechnology, biology, and medicine2010 Feb127-3619616128
Refinement of protein structures into low-resolution density maps using rosetta.DiMaio, Frank; Tyka, Michael D; Baker, Matthew L; Chiu, Wah; Baker, DavidJournal of molecular biology2009 Sep 11181-9019596339
Traction on immobilized netrin-1 is sufficient to reorient axons.Moore, Simon W; Biais, Nicolas; Sheetz, Michael PScience (New York, N.Y.)2009 Jul 1016619589994
NanoPen: dynamic, low-power, and light-actuated patterning of nanoparticles.Jamshidi, Arash; Neale, Steven L; Yu, Kyoungsik; Pauzauskie, Peter J; Schuck, Peter James; Valley, Justin K; Hsu, Hsan-Yin; Ohta, Aaron T; Wu, Ming CNano letters2009 Aug2921-519588985
Long noncoding RNAs: functional surprises from the RNA world.Wilusz, Jeremy E; Sunwoo, Hongjae; Spector, David LGenes & development2009 Jul 11494-50419571179
Inkjet formation of unilamellar lipid vesicles for cell-like encapsulation.Stachowiak, Jeanne C; Richmond, David L; Li, Thomas H; Brochard-Wyart, Francoise; Fletcher, Daniel ALab on a chip2009 Jul 212003-919568667
Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway.Liu, Cambrian Y; Fraser, Scott E; Koos, David SThe Journal of comparative neurology2009 Sep 136-4819565523
Molecular effects on boundary condition in micronanoliquid flows.Ulmanella, Umberto; Ho, Chih-MingPhysics of fluids (Woodbury, N.Y. : 1994)2008 Oct10151219547719
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Axon initiation and growth cone turning on bound protein gradients.Mai, Junyu; Fok, Lee; Gao, Hongfeng; Zhang, Xiang; Poo, Mu-MingThe Journal of neuroscience : the official journal of the Society for Neuroscience2009 Jun 107450-819515913
Capturing the nanoscale complexity of cellular membranes in supported lipid bilayers.Kam, Lance CJournal of structural biology2009 Oct10-Mar19500676
Characterization of lipid-templated silica and hybrid thin film mesophases by grazing incidence small-angle X-ray scattering.Dunphy, Darren R; Alam, Todd M; Tate, Michael P; Hillhouse, Hugh W; Smarsly, Bernd; Collord, Andrew D; Carnes, Eric; Baca, Helen K; Kohn, Ralf; Sprung, Michael; Wang, Jin; Brinker, C JeffreyLangmuir : the ACS journal of surfaces and colloids2009 Aug 189500-919496546
Gradient lithography of engineered proteins to fabricate 2D and 3D cell culture microenvironments.Wang, Sheng; Wong Po Foo, Cheryl; Warrier, Ajithkumar; Poo, Mu-Ming; Heilshorn, Sarah C; Zhang, XiangBiomedical microdevices2009 Oct1127-3419495986
Construction of bacteriophage phi29 DNA packaging motor and its applications in nanotechnology and therapy.Lee, Tae Jin; Schwartz, Chad; Guo, PeixuanAnnals of biomedical engineering2009 Oct2064-8119495981
Parallel single-cell light-induced electroporation and dielectrophoretic manipulation.Valley, Justin K; Neale, Steven; Hsu, Hsan-Yin; Ohta, Aaron T; Jamshidi, Arash; Wu, Ming CLab on a chip2009 Jun 211714-2019495455
Cell attachment behavior on solid and fluid substrates exhibiting spatial patterns of physical properties.Oliver, Ann E; Ngassam, Viviane; Dang, Phuong; Sanii, Babak; Wu, Huawen; Yee, Chanel K; Yeh, Yin; Parikh, Atul NLangmuir : the ACS journal of surfaces and colloids2009 Jun 166992-619453187
Pseudomonas aeruginosa Inhibition of Flagellin-activated NF-kappaB and interleukin-8 by human airway epithelial cells.Pena, Jose; Fu, Zhu; Schwarzer, Christian; Machen, Terry EInfection and immunity2009 Jul2857-6519451246
Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy.Cong, Yao; Zhang, Qinfen; Woolford, David; Schweikardt, Thorsten; Khant, Htet; Dougherty, Matthew; Ludtke, Steven J; Chiu, Wah; Decker, HeinzStructure (London, England : 1993)2009 May 13749-5819446530
Kinetic buffering of cross talk between bacterial two-component sensors.Groban, Eli S; Clarke, Elizabeth J; Salis, Howard M; Miller, Susan M; Voigt, Christopher AJournal of molecular biology2009 Jul 17380-9319445950
Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and delivery.Liu, Juewen; Jiang, Xingmao; Ashley, Carlee; Brinker, C JeffreyJournal of the American Chemical Society2009 Jun 107567-919445508
Plasma fluorination of diamond-like carbon surfaces: mechanism and application to nanoimprint lithography.Schvartzman, M; Wind, S JNanotechnology2009 Apr 814530619420525
Creation of functional micro/nano systems through top-down and bottom-up approaches.Wong, Tak-Sing; Brough, Branden; Ho, Chih-MingMolecular & cellular biomechanics : MCB2009 Mar1-5519382535
The cellular context of T cell signaling.Dustin, Michael LImmunity2009 Apr 17482-9219371714
The predicted structure of the headpiece of the Huntingtin protein and its implications on Huntingtin aggregation.Kelley, Nicholas W; Huang, Xuhui; Tam, Stephen; Spiess, Christoph; Frydman, Judith; Pande, Vijay SJournal of molecular biology2009 May 22919-2719361448
Optical properties of the crescent-shaped nanohole antenna.Wu, Liz Y; Ross, Benjamin M; Lee, Luke PNano letters2009 May1956-6119354226
A stochastic spectral analysis of transcriptional regulatory cascades.Walczak, Aleksandra M; Mugler, Andrew; Wiggins, Chris HProceedings of the National Academy of Sciences of the United States of America2009 Apr 216529-3419351901
T cell antigen receptor signaling and immunological synapse stability require myosin IIA.Ilani, Tal; Vasiliver-Shamis, Gaia; Vardhana, Santosh; Bretscher, Anthony; Dustin, Michael LNature immunology2009 May531-919349987
Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR.Numano, Rika; Szobota, Stephanie; Lau, Albert Y; Gorostiza, Pau; Volgraf, Matthew; Roux, Benoit; Trauner, Dirk; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America2009 Apr 216814-919342491
Nuclear neighborhoods and gene expression.Zhao, Rui; Bodnar, Megan S; Spector, David LCurrent opinion in genetics & development2009 Apr172-919339170
Trap profiles of projector based optoelectronic tweezers (OET) with HeLa cells.Neale, Steven L; Ohta, Aaron T; Hsu, Hsan-Yin; Valley, Justin K; Jamshidi, Arash; Wu, Ming COptics express2009 Mar 305232-919333286
The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation.Good, Matthew; Tang, Grace; Singleton, Julie; Remenyi, Attila; Lim, Wendell ACell2009 Mar 201085-9719303851
Cell kinase activity assay based on surface enhanced Raman spectroscopy.Yue, Zhicao; Zhuang, Fengfeng; Kumar, Rajar; Wang, Ieong; Cronin, Stephen B; Liu, Yi-HsinSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2009 Jul 15226-3019299194
Rigidity-dependent cross talk between integrin and cadherin signaling.Tsai, Jones; Kam, LanceBiophysical journal2009 Mar 18L39-4119289031
E. coli expression of a soluble, active single-chain antibody variable fragment containing a nuclear localization signal.Xiong, Hairong; Li, Shuyi; Yang, Zhanqiu; Burgess, Richard R; Dynan, William SProtein expression and purification2009 Aug172-8019281848
Early stages of oxidative stress-induced membrane permeabilization: a neutron reflectometry study.Smith, Hillary L; Howland, Michael C; Szmodis, Alan W; Li, Qijuan; Daemen, Luke L; Parikh, Atul N; Majewski, JaroslawJournal of the American Chemical Society2009 Mar 183631-819275260
Structural studies of HIV-1 Gag p6ct and its interaction with Vpr determined by solution nuclear magnetic resonance.Salgado, Gilmar F; Marquant, Rodrigue; Vogel, Alexander; Alves, Isabel D; Feller, Scott E; Morellet, Nelly; Bouaziz, SergeBiochemistry2009 Mar 242355-6719254034
Aptamer-based electrochemical biosensor for Botulinum neurotoxin.Wei, Fang; Ho, Chih-MingAnalytical and bioanalytical chemistry2009 Apr1943-819234874
Optimization strategies for electrospun silk fibroin tissue engineering scaffolds.Meinel, Anne J; Kubow, Kristopher E; Klotzsch, Enrico; Garcia-Fuentes, Marcos; Smith, Michael L; Vogel, Viola; Merkle, Hans P; Meinel, LorenzBiomaterials2009 Jun3058-6719233463
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The structural dynamics of macromolecular processes.Russel, Daniel; Lasker, Keren; Phillips, Jeremy; Schneidman-Duhovny, Dina; Velazquez-Muriel, Javier A; Sali, AndrejCurrent opinion in cell biology2009 Feb97-10819223165
Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways.Vogel, Viola; Sheetz, Michael PCurrent opinion in cell biology2009 Feb38-4619217273
Copolymeric nanofilm platform for controlled and localized therapeutic delivery.Chow, Edward Kai-Hua; Pierstorff, Erik; Cheng, Genhong; Ho, DeanACS nano2008 Jan33-4019206545
Impact of order and disorder in RGD nanopatterns on cell adhesion.Huang, Jinghuan; Grater, Stefan V; Corbellini, Francesca; Rinck, Sabine; Bock, Eva; Kemkemer, Ralf; Kessler, Horst; Ding, Jiandong; Spatz, Joachim PNano letters2009 Mar1111-619206508
Live cell interferometry reveals cellular dynamism during force propagation.Reed, Jason; Troke, Joshua J; Schmit, Joanna; Han, Sen; Teitell, Michael A; Gimzewski, James KACS nano2008 May841-619206480
Fabrication of massive sheets of single layer patterned arrays using lipid directed reengineered phi29 motor dodecamer.Xiao, Feng; Sun, Jinchuan; Coban, Oana; Schoen, Peter; Wang, Joseph Che-Yen; Cheng, R Holland; Guo, PeixuanACS nano2009 Jan 27100-719206255
An Improved United Atom Force Field for Simulation of Mixed Lipid Bilayers.Chiu, See-Wing; Pandit, Sagar A; Scott, H L; Jakobsson, EricThe journal of physical chemistry. B2009 Feb 9NULL19203242
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag.Wu, Peng; Shui, Wenqing; Carlson, Brian L; Hu, Nancy; Rabuka, David; Lee, Julia; Bertozzi, Carolyn RProceedings of the National Academy of Sciences of the United States of America2009 Mar 33000-519202059
Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility.Babor, Mariana; Kortemme, TanjaProteins2009 Jun846-5819194863
Porous nanoparticle supported lipid bilayers (protocells) as delivery vehicles.Liu, Juewen; Stace-Naughton, Alison; Jiang, Xingmao; Brinker, C JeffreyJournal of the American Chemical Society2009 Feb 41354-519173660
A role for the juxtamembrane cytoplasm in the molecular dynamics of focal adhesions.Wolfenson, Haguy; Lubelski, Ariel; Regev, Tamar; Klafter, Joseph; Henis, Yoav I; Geiger, BenjaminPloS one2009e430419172999
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Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas.Frank, Matthew J; Dawson, David W; Bensinger, Steven J; Hong, Jason S; Knosp, Wendy M; Xu, Lizhong; Balatoni, Cynthia E; Allen, Eric L; Shen, Rhine R; Bar-Sagi, Dafna; Martin, Gail R; Teitell, Michael ABlood2009 Mar 122478-8719147787
Remote optical switch for localized and selective control of gene interference.Lee, Somin Eunice; Liu, Gang Logan; Kim, Franklin; Lee, Luke PNano letters2009 Feb562-7019128006
Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain.Smith, Andrew M; Mohs, Aaron M; Nie, ShumingNature nanotechnology2009 Jan56-6319119284
Plasmon resonance energy transfer (PRET)-based molecular imaging of cytochrome c in living cells.Choi, Yeonho; Kang, Taewook; Lee, Luke PNano letters2009 Jan85-9019093833
Operational Regimes and Physics Present in Optoelectronic Tweezers.Valley, Justin K; Jamshidi, Arash; Ohta, Aaron T; Hsu, Hsan-Yin; Wu, Ming CJournal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems2008 Apr342-35019079767
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Reversible switching of pRNA activity on the DNA packaging motor of bacteriophage phi29.Ko, Seung Hyeon; Chen, Yi; Shu, Dan; Guo, Peixuan; Mao, ChengdeJournal of the American Chemical Society2008 Dec 3117684-719049308
Fibronectin in aging extracellular matrix fibrils is progressively unfolded by cells and elicits an enhanced rigidity response.Antia, Meher; Baneyx, Gretchen; Kubow, Kristopher E; Vogel, ViolaFaraday discussions2008229-49; discussion 309-25, 419-2019048998
Photolithographic patterning of organosilane monolayer for generating large area two-dimensional B lymphocyte arrays.Li, Nan; Ho, Chih-MingLab on a chip2008 Dec2105-1219023473
Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.Dubin-Thaler, Benjamin J; Hofman, Jake M; Cai, Yunfei; Xenias, Harry; Spielman, Ingrid; Shneidman, Anna V; David, Lawrence A; Dobereiner, Hans-Gunther; Wiggins, Chris H; Sheetz, Michael PPloS one2008e373519011687
Evidence for leaflet-dependent redistribution of charged molecules in fluid supported phospholipid bilayers.Shreve, Andrew P; Howland, Michael C; Sapuri-Butti, Annapoorna R; Allen, Toby W; Parikh, Atul NLangmuir : the ACS journal of surfaces and colloids2008 Dec 213250-319007257
Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells.Marriott, Gerard; Mao, Shu; Sakata, Tomoyo; Ran, Jing; Jackson, David K; Petchprayoon, Chutima; Gomez, Timothy J; Warp, Erica; Tulyathan, Orapim; Aaron, Holly L; Isacoff, Ehud Y; Yan, YulingProceedings of the National Academy of Sciences of the United States of America2008 Nov 1817789-9419004775
Designing artificial cells to harness the biological ion concentration gradient.Xu, Jian; Lavan, David ANature nanotechnology2008 Nov666-7018989332
Protein segment finder: an online search engine for segment motifs in the PDB.Samson, Abraham O; Levitt, MichaelNucleic acids research2009 JanD224-818974183
Structural transitions in ion coordination driven by changes in competition for ligand binding.Varma, Sameer; Rempe, Susan BJournal of the American Chemical Society2008 Nov 1915405-1918954053
Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging.Xiao, Feng; Zhang, Hui; Guo, PeixuanNucleic acids research2008 Nov6620-3218940870
NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells.Nitin, Nitin; Bao, GangBioconjugate chemistry2008 Nov 192205-1118939859
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Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage.Little, William C; Smith, Michael L; Ebneter, Urs; Vogel, ViolaMatrix biology : journal of the International Society for Matrix Biology2008 Jun451-6118417335
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Understanding and re-engineering nucleoprotein machines to cure human disease.Dynan, William; Takeda, Yoshihiko; Roth, David; Bao, GangNanomedicine (London, England)2008 Feb93-10518393669
Crystallization and preliminary X-ray diffraction analysis of recombinant hepatitis E virus-like particle.Wang, Che-Yen; Miyazaki, Naoyuki; Yamashita, Tetsuo; Higashiura, Akifumi; Nakagawa, Atsushi; Li, Tian-Cheng; Takeda, Naokazu; Xing, Li; Hjalmarsson, Erik; Friberg, Claes; Liou, Der-Ming; Sung, Yen-Jen; Tsukihara, Tomitake; Matsuura, Yoshiharu; Miyamura, TActa crystallographica. Section F, Structural biology and crystallization communications2008 Apr 1318-2218391436
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Inhibition mechanism of the acetylcholine receptor by alpha-neurotoxins as revealed by normal-mode dynamics.Samson, Abraham O; Levitt, MichaelBiochemistry2008 Apr 14065-7018327915
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Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species.Slavoff, Sarah A; Chen, Irwin; Choi, Yoon-Aa; Ting, Alice YJournal of the American Chemical Society2008 Jan 301160-218171066
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Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding.Ruan, Gang; Agrawal, Amit; Marcus, Adam I; Nie, ShumingJournal of the American Chemical Society2007 Nov 2814759-6617983227
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Modifying the function of DNA repair nanomachines for therapeutic benefit.Dynan, William S; Takeda, Yoshihiko; Li, ShuyiNanomedicine : nanotechnology, biology, and medicine2006 Jun74-8117292118
Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.Dawson, D W; Hong, J S; Shen, R R; French, S W; Troke, J J; Wu, Y-Z; Chen, S-S; Gui, D; Regelson, M; Marahrens, Y; Morse 3rd, H C; Said, J; Plass, C; Teitell, M AOncogene2007 Jun 214243-5217260020
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