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Nanomedicine (575)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.Bakthavatsalam, Deenadayalan; Soung, Roh Hun; Tweardy, David J; Chiu, Wah; Dixon, Richard A F; Woodside, Darren GFEBS letters2014 Jun 132133-4024846140
Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.Schwarzer, Christian; Ravishankar, Bharat; Patanwala, Maria; Shuai, Stacey; Fu, Zhu; Illek, Beate; Fischer, Horst; Machen, Terry EAmerican journal of physiology. Cell physiology2014 May 1C844-5524598360
Stoichiometry and specific assembly of Best ion channels.Bharill, Shashank; Fu, Zhu; Palty, Raz; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America2014 Apr 296491-624748110
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.Bendall, Sean C; Davis, Kara L; Amir, El-Ad David; Tadmor, Michelle D; Simonds, Erin F; Chen, Tiffany J; Shenfeld, Daniel K; Nolan, Garry P; Pe'er, DanaCell2014 Apr 24714-2524766814
Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal.Park, Jason S; Rhau, Benjamin; Hermann, Aynur; McNally, Krista A; Zhou, Carmen; Gong, Delquin; Weiner, Orion D; Conklin, Bruce R; Onuffer, James; Lim, Wendell AProceedings of the National Academy of Sciences of the United States of America2014 Apr 225896-90124711398
Genetic and Pharmacological Strategies to Refunctionalize the von Hippel Lindau R167Q Mutant Protein.Ding, Zhiyong; German, Peter; Bai, Shanshan; Reddy, A Srinivas; Liu, Xian-De; Sun, Mianen; Zhou, Lijun; Chen, Xiaohua; Zhao, Xiaobei; Wu, Chengbiao; Zhang, Shuxing; Mills, Gordon B; Jonasch, EricCancer research2014 Apr 22NULL24755468
Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing.Hendel, Ayal; Kildebeck, Eric J; Fine, Eli J; Clark, Joseph T; Punjya, Niraj; Sebastiano, Vittorio; Bao, Gang; Porteus, Matthew HCell reports2014 Apr 10293-30524685129
Retinoschisin gene therapy in photoreceptors, Muller glia or all retinal cells in the Rs1h-/- mouse.Byrne, L C; Ozturk, B E; Lee, T; Fortuny, C; Visel, M; Dalkara, D; Schaffer, D V; Flannery, J GGene therapy2014 Apr 3NULL24694538
An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.Fine, Eli J; Cradick, Thomas J; Zhao, Charles L; Lin, Yanni; Bao, GangNucleic acids research2014 Apre4224381193
SAPTA: a new design tool for improving TALE nuclease activity.Lin, Yanni; Fine, Eli J; Zheng, Zhilan; Antico, Christopher J; Voit, Richard A; Porteus, Matthew H; Cradick, Thomas J; Bao, GangNucleic acids research2014 Apre4724442582
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.Zhang, Xian; Moore, Simon W; Iskratsch, Thomas; Sheetz, Michael PJournal of cell science2014 Apr 11394-40524481817
Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy.Reiner, Andreas; Isacoff, Ehud YNature chemical biology2014 Apr273-8024561661
Multiplexed ion beam imaging of human breast tumors.Angelo, Michael; Bendall, Sean C; Finck, Rachel; Hale, Matthew B; Hitzman, Chuck; Borowsky, Alexander D; Levenson, Richard M; Lowe, John B; Liu, Scot D; Zhao, Shuchun; Natkunam, Yasodha; Nolan, Garry PNature medicine2014 Apr436-4224584119
Modulation of STAT3 folding and function by TRiC/CCT chaperonin.Kasembeli, Moses; Lau, Wilson Chun Yu; Roh, Soung-Hun; Eckols, T Kris; Frydman, Judith; Chiu, Wah; Tweardy, David JPLoS biology2014 Apre100184424756126
A molecular interpretation of 2D IR protein folding experiments with Markov state models.Baiz, Carlos R; Lin, Yu-Shan; Peng, Chunte Sam; Beauchamp, Kyle A; Voelz, Vincent A; Pande, Vijay S; Tokmakoff, AndreiBiophysical journal2014 Mar 181359-7024655511
Group II archaeal chaperonin recognition of partially folded human ýýD-crystallin mutants.Sergeeva, Oksana A; Yang, Jingkun; King, Jonathan A; Knee, Kelly MProtein science : a publication of the Protein Society2014 Mar 10NULL24615724
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse.Choudhuri, Kaushik; Llodra, Jaime; Roth, Eric W; Tsai, Jones; Gordo, Susana; Wucherpfennig, Kai W; Kam, Lance C; Stokes, David L; Dustin, Michael LNature2014 Mar 6118-2324487619
Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility.Bashour, Keenan T; Tsai, Jones; Shen, Keyue; Lee, Joung-Hyun; Sun, Eileen; Milone, Michael C; Dustin, Michael L; Kam, Lance CMolecular and cellular biology2014 Mar955-6424379441
Use of cell morphology as early bioindicator for viral infection.Ding, Xianting; Liu, Ningxia; Matsuo, Kyle; Sun, Mingzhu; Zhao, XinIET nanobiotechnology / IET2014 Mar24-3024888188
Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells.Tochitsky, Ivan; Polosukhina, Aleksandra; Degtyar, Vadim E; Gallerani, Nicholas; Smith, Caleb M; Friedman, Aaron; Van Gelder, Russell N; Trauner, Dirk; Kaufer, Daniela; Kramer, Richard HNeuron2014 Feb 19800-1324559673
CD28 and CD3 have complementary roles in T-cell traction forces.Bashour, Keenan T; Gondarenko, Alexander; Chen, Haoqian; Shen, Keyue; Liu, Xin; Huse, Morgan; Hone, James C; Kam, Lance CProceedings of the National Academy of Sciences of the United States of America2014 Feb 112241-624469820
Secreting and sensing the same molecule allows cells to achieve versatile social behaviors.Youk, Hyun; Lim, Wendell AScience (New York, N.Y.)2014 Feb 7124278224503857
T cell antigen receptor activation and actin cytoskeleton remodeling.Kumari, Sudha; Curado, Silvia; Mayya, Viveka; Dustin, Michael LBiochimica et biophysica acta2014 Feb546-5623680625
Electrical impedance monitoring of photothermal porated mammalian cells.Yamane, Daisuke; Wu, Yi-Chien; Wu, Ting-Hsiang; Toshiyoshi, Hiroshi; Teitell, Michael A; Chiou, Pei-YuJournal of laboratory automation2014 Feb50-923797097
Nanomedicine: tiny particles and machines give huge gains.Tong, Sheng; Fine, Eli J; Lin, Yanni; Cradick, Thomas J; Bao, GangAnnals of biomedical engineering2014 Feb243-5924297494
Focal damage to macaque photoreceptors produces persistent visual loss.Strazzeri, Jennifer M; Hunter, Jennifer J; Masella, Benjamin D; Yin, Lu; Fischer, William S; DiLoreto Jr, David A; Libby, Richard T; Williams, David R; Merigan, William HExperimental eye research2014 Feb88-9624316158
Pseudomonas aeruginosa Homoserine Lactone Triggers Apoptosis and Bak/Bax-Independent Release of Mitochondrial Cytochrome C in Fibroblasts.Schwarzer, Christian; Fu, Zhu; Shuai, Stacey; Babbar, Salil; Zhao, Guoping; Li, Chi; Machen, Terry ECellular microbiology2014 Jan 20NULL24438098
Nuclease-mediated gene editing by homologous recombination of the human globin locus.Voit, Richard A; Hendel, Ayal; Pruett-Miller, Shondra M; Porteus, Matthew HNucleic acids research2014 Jan1365-7824157834
Modeling of proteins and their assemblies with the Integrative Modeling Platform.Webb, Benjamin; Lasker, Keren; Velazquez-Muriel, Javier; Schneidman-Duhovny, Dina; Pellarin, Riccardo; Bonomi, Massimiliano; Greenberg, Charles; Raveh, Barak; Tjioe, Elina; Russel, Daniel; Sali, AndrejMethods in molecular biology (Clifton, N.J.)2014277-9524203340
Local plasticity of dendritic excitability can be autonomous of synaptic plasticity and regulated by activity-based phosphorylation of Kv4.2.Labno, Anna; Warrier, Ajithkumar; Wang, Sheng; Zhang, XiangPloS one2014e8408624404150
Micropatterned, multicomponent supported lipid bilayers for cellular systems.Dutta, Debjit; Kam, Lance CMethods in cell biology201453-6724484657
Designing and testing the activities of TAL effector nucleases.Lin, Yanni; Cradick, Thomas J; Bao, GangMethods in molecular biology (Clifton, N.J.)2014203-1924557905
An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases.Lindsay, Cory R; Roth, David BMethods in molecular biology (Clifton, N.J.)2014353-6924557915
Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.Fine, Eli J; Cradick, Thomas J; Bao, GangMethods in molecular biology (Clifton, N.J.)2014371-8324557916
Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography.Shahmoradian, Sarah H; Galiano, Mauricio R; Wu, Chengbiao; Chen, Shurui; Rasband, Matthew N; Mobley, William C; Chiu, WahJournal of visualized experiments : JoVE2014e5078324561719
Photoswitching of cell surface receptors using tethered ligands.Reiner, Andreas; Isacoff, Ehud YMethods in molecular biology (Clifton, N.J.)201445-6824718794
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration.Iskratsch, Thomas; Yu, Cheng-Han; Mathur, Anurag; Liu, Shuaimin; Stevenin, Virginie; Dwyer, Joseph; Hone, James; Ehler, Elisabeth; Sheetz, MichaelDevelopmental cell2013 Dec 9545-5924331927
Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Toettcher, Jared E; Weiner, Orion D; Lim, Wendell ACell2013 Dec 51422-3424315106
Reprogramming an ATP-driven protein machine into a light-gated nanocage.Hoersch, Daniel; Roh, Soung-Hun; Chiu, Wah; Kortemme, TanjaNature nanotechnology2013 Dec928-3224270642
A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor.Kienzler, Michael A; Reiner, Andreas; Trautman, Eric; Yoo, Stan; Trauner, Dirk; Isacoff, Ehud YJournal of the American Chemical Society2013 Nov 2717683-624171511
Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ib*.Kruss, Sebastian; Erpenbeck, Luise; Amschler, Katharina; Mundinger, Tabea A; Boehm, Heike; Helms, Hans-Joachim; Friede, Tim; Andrews, Robert K; Schon, Michael P; Spatz, Joachim PACS nano2013 Nov 269984-9624093566
T cell activation is determined by the number of presented antigens.Deeg, Janosch; Axmann, Markus; Matic, Jovana; Liapis, Anastasia; Depoil, David; Afrose, Jehan; Curado, Silvia; Dustin, Michael L; Spatz, Joachim PNano letters2013 Nov 135619-2624117051
Nanoscale ligand spacing influences receptor triggering in T cells and NK cells.Delcassian, Derfogail; Depoil, David; Rudnicka, Dominika; Liu, Mengling; Davis, Daniel M; Dustin, Michael L; Dunlop, Iain ENano letters2013 Nov 135608-1424125583
Intracellular delivery of top-down fabricated tunable nano-plasmonic resonators.Ota, Sadao; Wang, Sheng; Ryu, Jongeun; Wang, Yuan; Chen, Yong; Zhang, XiangNanoscale2013 Nov 710179-8224056760
CRISPR/Cas9 systems targeting *-globin and CCR5 genes have substantial off-target activity.Cradick, Thomas J; Fine, Eli J; Antico, Christopher J; Bao, GangNucleic acids research2013 Nov 19584-9223939622
Visualizing virus assembly intermediates inside marine cyanobacteria.Dai, Wei; Fu, Caroline; Raytcheva, Desislava; Flanagan, John; Khant, Htet A; Liu, Xiangan; Rochat, Ryan H; Haase-Pettingell, Cameron; Piret, Jacqueline; Ludtke, Steve J; Nagayama, Kuniaki; Schmid, Michael F; King, Jonathan A; Chiu, WahNature2013 Oct 31707-1024107993
Genetic Sensor for Strong Methylating Compounds.Moser, Felix; Horwitz, Andrew; Chen, Jacinto; Lim, Wendell A; Voigt, Christopher AACS synthetic biology2013 Oct 9NULL24032656
Super-resolution fluorescence imaging with single molecules.Sahl, Steffen J; Moerner, W ECurrent opinion in structural biology2013 Oct778-8723932284
Receptor-mediated delivery of engineered nucleases for genome modification.Chen, Zhong; Jaafar, Lahcen; Agyekum, Davies G; Xiao, Haiyan; Wade, Marlene F; Kumaran, R Ileng; Spector, David L; Bao, Gang; Porteus, Matthew H; Dynan, William S; Meiler, Steffen ENucleic acids research2013 Octe18223956220
Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress.Escusa-Toret, Stephanie; Vonk, Willianne I M; Frydman, JudithNature cell biology2013 Oct1231-4324036477
The Brain Prize 2013: the optogenetics revolution.Reiner, Andreas; Isacoff, Ehud YTrends in neurosciences2013 Oct557-6024054067
DNA targeting specificity of RNA-guided Cas9 nucleases.Hsu, Patrick D; Scott, David A; Weinstein, Joshua A; Ran, F Ann; Konermann, Silvana; Agarwala, Vineeta; Li, Yinqing; Fine, Eli J; Wu, Xuebing; Shalem, Ophir; Cradick, Thomas J; Marraffini, Luciano A; Bao, Gang; Zhang, FengNature biotechnology2013 Sep827-3223873081
Accurate SAXS profile computation and its assessment by contrast variation experiments.Schneidman-Duhovny, Dina; Hammel, Michal; Tainer, John A; Sali, AndrejBiophysical journal2013 Aug 20962-7423972848
Exploitation of latent allostery enables the evolution of new modes of MAP kinase regulation.Coyle, Scott M; Flores, Jonathan; Lim, Wendell ACell2013 Aug 15875-8723953117
Targeting H3K4 trimethylation in Huntington disease.Vashishtha, Malini; Ng, Christopher W; Yildirim, Ferah; Gipson, Theresa A; Kratter, Ian H; Bodai, Laszlo; Song, Wan; Lau, Alice; Labadorf, Adam; Vogel-Ciernia, Annie; Troncosco, Juan; Ross, Christopher A; Bates, Gillian P; Krainc, Dimitri; Sadri-Vakili, GProceedings of the National Academy of Sciences of the United States of America2013 Aug 6E3027-3623872847
Quantification of biomass and cell motion in human pluripotent stem cell colonies.Zangle, Thomas A; Chun, Jennifer; Zhang, Jin; Reed, Jason; Teitell, Michael ABiophysical journal2013 Aug 6593-60123931307
Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops: A New Tool for the Measurement of Cell Traction Forces Transmitted through *v *3 - or *5 *1 -Integrins.Rahmouni, Sabri; Lindner, Aaron; Rechenmacher, Florian; Neubauer, Stefanie; Sobahi, Tariq Rashad Ali; Kessler, Horst; Cavalcanti-Adam, Elisabetta Ada; Spatz, Joachim PiusAdvanced materials (Deerfield Beach, Fla.)2013 Aug 5NULL23913640
Ultrastable pRNA hexameric ring gearing hexameric phi29 DNA-packaging motor by revolving without rotating and coiling.Schwartz, Chad; Guo, PeixuanCurrent opinion in biotechnology2013 Aug581-9023683853
Aging and intellectual disability: Insights from mouse models of down syndrome.Ruparelia, Aarti; Pearn, Matthew L; Mobley, William CDevelopmental disabilities research reviews2013 Aug43-5023949828
Single-cell mass cytometry for analysis of immune system functional states.Bjornson, Zach B; Nolan, Garry P; Fantl, Wendy JCurrent opinion in immunology2013 Aug484-9423999316
Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling.Baker, Matthew L; Hryc, Corey F; Zhang, Qinfen; Wu, Weimin; Jakana, Joanita; Haase-Pettingell, Cameron; Afonine, Pavel V; Adams, Paul D; King, Jonathan A; Jiang, Wen; Chiu, WahProceedings of the National Academy of Sciences of the United States of America2013 Jul 2312301-623840063
Coffee ring aptasensor for rapid protein detection.Wen, Jessica T; Ho, Chih-Ming; Lillehoj, Peter BLangmuir : the ACS journal of surfaces and colloids2013 Jul 28440-623540796
Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers.Sergeeva, Oksana A; Chen, Bo; Haase-Pettingell, Cameron; Ludtke, Steven J; Chiu, Wah; King, Jonathan AThe Journal of biological chemistry2013 Jun 1417734-4423612981
In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous.Dalkara, Deniz; Byrne, Leah C; Klimczak, Ryan R; Visel, Meike; Yin, Lu; Merigan, William H; Flannery, John G; Schaffer, David VScience translational medicine2013 Jun 12189ra7623761039
Chromatin meets its organizers.Bodnar, Megan S; Spector, David LCell2013 Jun 61187-923746835
Visualizing GroEL/ES in the act of encapsulating a folding protein.Chen, Dong-Hua; Madan, Damian; Weaver, Jeremy; Lin, Zong; Schroder, Gunnar F; Chiu, Wah; Rye, Hays SCell2013 Jun 61354-6523746846
Different mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons.Bertke, Andrea S; Ma, AyeAye; Margolis, Mathew S; Margolis, Todd PJournal of virology2013 Jun6512-623514893
Cryo-EM model validation using independent map reconstructions.DiMaio, Frank; Zhang, Junjie; Chiu, Wah; Baker, DavidProtein science : a publication of the Protein Society2013 Jun865-823592445
Rapid feedback regulation of synaptic efficacy during high-frequency activity at the Drosophila larval neuromuscular junction.Kauwe, Grant; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America2013 May 289142-723674684
Imaging light responses of retinal ganglion cells in the living mouse eye.Yin, Lu; Geng, Ying; Osakada, Fumitaka; Sharma, Robin; Cetin, Ali H; Callaway, Edward M; Williams, David R; Merigan, William HJournal of neurophysiology2013 May2415-2123407356
Parametric Bayesian priors and better choice of negative examples improve protein function prediction.Youngs, Noah; Penfold-Brown, Duncan; Drew, Kevin; Shasha, Dennis; Bonneau, RichardBioinformatics (Oxford, England)2013 May 11190-823511543
Normalization of mass cytometry data with bead standards.Finck, Rachel; Simonds, Erin F; Jager, Astraea; Krishnaswamy, Smita; Sachs, Karen; Fantl, Wendy; Pe'er, Dana; Nolan, Garry P; Bendall, Sean CCytometry. Part A : the journal of the International Society for Analytical Cytology2013 May483-9423512433
Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling.Zhang, Kai; Fishel Ben Kenan, Rotem; Osakada, Yasuko; Xu, Wei; Sinit, Rachel S; Chen, Liang; Zhao, Xiaobei; Chen, Jia-Yun; Cui, Bianxiao; Wu, ChengbiaoThe Journal of neuroscience : the official journal of the Society for Neuroscience2013 Apr 247451-6223616551
Robust data-driven incorporation of prior knowledge into the inference of dynamic regulatory networks.Greenfield, Alex; Hafemeister, Christoph; Bonneau, RichardBioinformatics (Oxford, England)2013 Apr 151060-723525069
Integrin-dependent force transmission to the extracellular matrix by ýý-actinin triggers adhesion maturation.Roca-Cusachs, Pere; del Rio, Armando; Puklin-Faucher, Eileen; Gauthier, Nils C; Biais, Nicolas; Sheetz, Michael PProceedings of the National Academy of Sciences of the United States of America2013 Apr 9E1361-7023515331
Cell-based therapeutics: the next pillar of medicine.Fischbach, Michael A; Bluestone, Jeffrey A; Lim, Wendell AScience translational medicine2013 Apr 3179ps723552369
Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation.Best, J Adam; Blair, David A; Knell, Jamie; Yang, Edward; Mayya, Viveka; Doedens, Andrew; Dustin, Michael L; Goldrath, Ananda W; Immunological Genome Project ConsortiumNature immunology2013 Apr404-1223396170
A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells.Imberg-Kazdan, Keren; Ha, Susan; Greenfield, Alex; Poultney, Christopher S; Bonneau, Richard; Logan, Susan K; Garabedian, Michael JGenome research2013 Apr581-9123403032
Optical control of metabotropic glutamate receptors.Levitz, Joshua; Pantoja, Carlos; Gaub, Benjamin; Janovjak, Harald; Reiner, Andreas; Hoagland, Adam; Schoppik, David; Kane, Brian; Stawski, Philipp; Schier, Alexander F; Trauner, Dirk; Isacoff, Ehud YNature neuroscience2013 Apr507-1623455609
AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting.Hastie, Peter; Ulbrich, Maximilian H; Wang, Hui-Li; Arant, Ryan J; Lau, Anthony G; Zhang, Zhenjie; Isacoff, Ehud Y; Chen, LuProceedings of the National Academy of Sciences of the United States of America2013 Mar 265163-823479622
Dynamic regulation of the structure and functions of integrin adhesions.Wolfenson, Haguy; Lavelin, Irena; Geiger, BenjaminDevelopmental cell2013 Mar 11447-5823484852
Synthesis of nanostructured and biofunctionalized water-in-oil droplets as tools for homing T cells.Platzman, Ilia; Janiesch, Jan-Willi; Spatz, Joachim PiusJournal of the American Chemical Society2013 Mar 63339-4223419177
Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitro.Knee, Kelly M; Sergeeva, Oksana A; King, Jonathan ACell stress & chaperones2013 Mar137-4423011926
Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes.Sontag, Emily M; Joachimiak, Lukasz A; Tan, Zhiqun; Tomlinson, Anthony; Housman, David E; Glabe, Charles G; Potkin, Steven G; Frydman, Judith; Thompson, Leslie MProceedings of the National Academy of Sciences of the United States of America2013 Feb 193077-8223365139
Reversible optical control of cyanine fluorescence in fixed and living cells: optical lock-in detection immunofluorescence imaging microscopy.Yan, Yuling; Petchprayoon, Chutima; Mao, Shu; Marriott, GerardPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2013 Feb 52012003123267183
Reversible regulation of aptamer activity with effector-responsive hairpin oligonucleotides.Li, NaJournal of laboratory automation2013 Feb77-8422651934
EMEN2: an object oriented database and electronic lab notebook.Rees, Ian; Langley, Ed; Chiu, Wah; Ludtke, Steven JMicroscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada2013 Feb10-Jan23360752
Solid-State and Biological Nanopore for Real-Time Sensing of Single Chemical and Sequencing of DNA.Haque, Farzin; Li, Jinghong; Wu, Hai-Chen; Liang, Xing-Jie; Guo, PeixuanNano today2013 Feb56-7423504223
Application of fractional factorial designs to study drug combinations.Jaynes, Jessica; Ding, Xianting; Xu, Hongquan; Wong, Weng Kee; Ho, Chih-MingStatistics in medicine2013 Jan 30307-1822859316
Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs.Ellis, B L; Hirsch, M L; Porter, S N; Samulski, R J; Porteus, M HGene therapy2013 Jan35-4222257934
Investigative and clinical applications of synthetic immune synapses.Milone, Michael C; Kam, Lance CWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2013 Jan-Feb75-8522927243
Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.Kunii, Naoki; Zhao, Yangbing; Jiang, Shuguang; Liu, Xiaojun; Scholler, John; Balagopalan, Lakshmi; Samelson, Lawrence E; Milone, Michael C; June, Carl HHuman gene therapy2013 Jan27-3722998346
Multifunctional nanoparticles for drug delivery and molecular imaging.Bao, Gang; Mitragotri, Samir; Tong, ShengAnnual review of biomedical engineering2013253-8223642243
Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE).Lyskov, Sergey; Chou, Fang-Chieh; Conchuir, Shane O; Der, Bryan S; Drew, Kevin; Kuroda, Daisuke; Xu, Jianqing; Weitzner, Brian D; Renfrew, P Douglas; Sripakdeevong, Parin; Borgo, Benjamin; Havranek, James J; Kuhlman, Brian; Kortemme, Tanja; Bonneau, RichaPloS one2013e6390623717507
High-contrast fluorescence imaging in fixed and living cells using optimized optical switches.Wu, Liangxing; Dai, Yingrui; Jiang, Xiaoli; Petchprayoon, Chutima; Lee, Jessie E; Jiang, Tao; Yan, Yuling; Marriott, GerardPloS one2013e6473823755140
Micro- and nanoscale engineering of cell signaling.Kam, L C; Shen, K; Dustin, M LAnnual review of biomedical engineering2013305-2623862677
Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design.Drew, Kevin; Renfrew, P Douglas; Craven, Timothy W; Butterfoss, Glenn L; Chou, Fang-Chieh; Lyskov, Sergey; Bullock, Brooke N; Watkins, Andrew; Labonte, Jason W; Pacella, Michael; Kilambi, Krishna Praneeth; Leaver-Fay, Andrew; Kuhlman, Brian; Gray, JeffreyPloS one2013e6705123869206
Differential effect of actomyosin relaxation on the dynamic properties of focal adhesion proteins.Lavelin, Irena; Wolfenson, Haguy; Patla, Israel; Henis, Yoav I; Medalia, Ohad; Volberg, Tova; Livne, Ariel; Kam, Zvi; Geiger, BenjaminPloS one2013e7354924039980
Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage.Deriano, Ludovic; Roth, David BAnnual review of genetics2013433-5524050180
Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils.Dandekar, Sheel N; Park, Jason S; Peng, Grace E; Onuffer, James J; Lim, Wendell A; Weiner, Orion DPhilosophical transactions of the Royal Society of London. Series B, Biological sciences20132013000824062580
Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control.Honda, Yoshitomo; Ding, Xianting; Mussano, Federico; Wiberg, Akira; Ho, Chih-Ming; Nishimura, IchiroScientific reports2013342024305548
Effects of familial mutations on the monomer structure of Aýýýýýýýý.Lin, Yu-Shan; Pande, Vijay SBiophysical journal2012 Dec 19L47-923260058
Rapidly quantifying drug sensitivity of dispersed and clumped breast cancer cells by mass profiling.Chun, Jennifer; Zangle, Thomas A; Kolarova, Theodora; Finn, Richard S; Teitell, Michael A; Reed, JasonThe Analyst2012 Dec 75495-823057068
Regulation of integrin adhesions by varying the density of substrate-bound epidermal growth factor.Shahal, Tamar; Geiger, Benjamin; Dunlop, Iain E; Spatz, Joachim PBiointerphases2012 Dec2322589066
Probing single biomolecules in solution using the anti-Brownian electrokinetic (ABEL) trap.Wang, Quan; Goldsmith, Randall H; Jiang, Yan; Bockenhauer, Samuel D; Moerner, W EAccounts of chemical research2012 Nov 201955-6422616716
Enhanced ýý-secretase processing alters APP axonal transport and leads to axonal defects.Rodrigues, Elizabeth M; Weissmiller, April M; Goldstein, Lawrence S BHuman molecular genetics2012 Nov 14587-60122843498
A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.Reissmann, Stefanie; Joachimiak, Lukasz A; Chen, Bryan; Meyer, Anne S; Nguyen, Anthony; Frydman, JudithCell reports2012 Oct 25866-7723041314
A validated regulatory network for Th17 cell specification.Ciofani, Maria; Madar, Aviv; Galan, Carolina; Sellars, Maclean; Mace, Kieran; Pauli, Florencia; Agarwal, Ashish; Huang, Wendy; Parkurst, Christopher N; Muratet, Michael; Newberry, Kim M; Meadows, Sarah; Greenfield, Alex; Yang, Yi; Jain, Preti; Kirigin, FrCell2012 Oct 12289-30323021777
Designing synthetic regulatory networks capable of self-organizing cell polarization.Chau, Angela H; Walter, Jessica M; Gerardin, Jaline; Tang, Chao; Lim, Wendell ACell2012 Oct 12320-3223039994
Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome.Ruparelia, Aarti; Pearn, Matthew L; Mobley, William CCurrent opinion in neurobiology2012 Oct880-622658745
Formation of lipid bilayers inside microfluidic channel array for monitoring membrane-embedded nanopores of phi29 DNA packaging nanomotor.Shim, Joon S; Geng, Jia; Ahn, Chong H; Guo, PeixuanBiomedical microdevices2012 Oct921-822773160
Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.Ruocco, Maria Grazia; Pilones, Karsten A; Kawashima, Noriko; Cammer, Michael; Huang, Julie; Babb, James S; Liu, Mengling; Formenti, Silvia C; Dustin, Michael L; Demaria, SandraThe Journal of clinical investigation2012 Oct 13718-3022945631
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Photonic gene circuits by optically addressable siRNA-Au nanoantennas.Lee, Somin Eunice; Sasaki, Darryl Y; Park, Younggeun; Xu, Ren; Brennan, James S; Bissell, Mina J; Lee, Luke PACS nano2012 Sep 257770-8022827439
Circular, nanostructured and biofunctionalized hydrogel microchannels for dynamic cell adhesion studies.Kruss, Sebastian; Erpenbeck, Luise; Schon, Michael P; Spatz, Joachim PLab on a chip2012 Sep 213285-922858992
Assembly of DNA curtains using hydrogen silsesquioxane as a barrier to lipid diffusion.Fazio, T A; Lee, Ja Yil; Wind, S J; Greene, E CAnalytical chemistry2012 Sep 187613-722946619
The first World Cell Race.Maiuri, Paolo; Terriac, Emmanuel; Paul-Gilloteaux, Perrine; Vignaud, Timothee; McNally, Krista; Onuffer, James; Thorn, Kurt; Nguyen, Phuong A; Georgoulia, Nefeli; Soong, Daniel; Jayo, Asier; Beil, Nina; Beneke, Jurgen; Lim, Joleen Chooi Hong; Sim, Chloe PCurrent biology : CB2012 Sep 11R673-522974990
Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.Zalatan, Jesse G; Coyle, Scott M; Rajan, Saravanan; Sidhu, Sachdev S; Lim, Wendell AScience (New York, N.Y.)2012 Sep 71218-2222878499
De novo structure prediction and experimental characterization of folded peptoid oligomers.Butterfoss, Glenn L; Yoo, Barney; Jaworski, Jonathan N; Chorny, Ilya; Dill, Ken A; Zuckermann, Ronald N; Bonneau, Richard; Kirshenbaum, Kent; Voelz, Vincent AProceedings of the National Academy of Sciences of the United States of America2012 Sep 414320-522908242
UCSF Chimera, MODELLER, and IMP: an integrated modeling system.Yang, Zheng; Lasker, Keren; Schneidman-Duhovny, Dina; Webb, Ben; Huang, Conrad C; Pettersen, Eric F; Goddard, Thomas D; Meng, Elaine C; Sali, Andrej; Ferrin, Thomas EJournal of structural biology2012 Sep269-7821963794
Netrin-1 attracts axons through FAK-dependent mechanotransduction.Moore, Simon W; Zhang, Xian; Lynch, Christopher D; Sheetz, Michael PThe Journal of neuroscience : the official journal of the Society for Neuroscience2012 Aug 2211574-8522915102
Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells.Wei, Ping; Wong, Wilson W; Park, Jason S; Corcoran, Ethan E; Peisajovich, Sergio G; Onuffer, James J; Weiss, Arthur; Lim, Wendell ANature2012 Aug 16384-822820255
Activation of specific interneurons improves V1 feature selectivity and visual perception.Lee, Seung-Hee; Kwan, Alex C; Zhang, Siyu; Phoumthipphavong, Victoria; Flannery, John G; Masmanidis, Sotiris C; Taniguchi, Hiroki; Huang, Z Josh; Zhang, Feng; Boyden, Edward S; Deisseroth, Karl; Dan, YangNature2012 Aug 16379-8322878719
Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models.Sontag, Emily Mitchell; Lotz, Gregor P; Agrawal, Namita; Tran, Andrew; Aron, Rebecca; Yang, Guocheng; Necula, Mihaela; Lau, Alice; Finkbeiner, Steven; Glabe, Charles; Marsh, J Lawrence; Muchowski, Paul J; Thompson, Leslie MThe Journal of neuroscience : the official journal of the Society for Neuroscience2012 Aug 811109-1922875942
Substrate rigidity regulates human T cell activation and proliferation.O'Connor, Roddy S; Hao, Xueli; Shen, Keyue; Bashour, Keenan; Akimova, Tatiana; Hancock, Wayne W; Kam, Lance C; Milone, Michael CJournal of immunology (Baltimore, Md. : 1950)2012 Aug 11330-922732590
Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology.Guo, Peixuan; Haque, Farzin; Hallahan, Brent; Reif, Randall; Li, HuiNucleic acid therapeutics2012 Aug226-4522913595
Photochemical restoration of visual responses in blind mice.Polosukhina, Aleksandra; Litt, Jeffrey; Tochitsky, Ivan; Nemargut, Joseph; Sychev, Yivgeny; De Kouchkovsky, Ivan; Huang, Tracy; Borges, Katharine; Trauner, Dirk; Van Gelder, Russell N; Kramer, Richard HNeuron2012 Jul 26271-8222841312
Systematic functional prioritization of protein posttranslational modifications.Beltrao, Pedro; Albanese, Veronique; Kenner, Lillian R; Swaney, Danielle L; Burlingame, Alma; Villen, Judit; Lim, Wendell A; Fraser, James S; Frydman, Judith; Krogan, Nevan JCell2012 Jul 20413-2522817900
Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit.Xiong, Hairong; Lee, Robert J; Haura, Eric B; Edwards, John G; Dynan, William S; Li, ShuyiInternational journal of radiation oncology, biology, physics2012 Jul 11023-3022138455
The role of feature curvature in contact guidance.Mathur, Anurag; Moore, Simon W; Sheetz, Michael P; Hone, JamesActa biomaterialia2012 Jul2595-60122426288
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Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling.Sandoz, Guillaume; Levitz, Joshua; Kramer, Richard H; Isacoff, Ehud YNeuron2012 Jun 211005-1422726831
F-actin polymerization and retrograde flow drive sustained PLCýý1 signaling during T cell activation.Babich, Alexander; Li, Shuixing; O'Connor, Roddy S; Milone, Michael C; Freedman, Bruce D; Burkhardt, Janis KThe Journal of cell biology2012 Jun 11775-8722665519
The molecular architecture of the eukaryotic chaperonin TRiC/CCT.Leitner, Alexander; Joachimiak, Lukasz A; Bracher, Andreas; Monkemeyer, Leonie; Walzthoeni, Thomas; Chen, Bryan; Pechmann, Sebastian; Holmes, Susan; Cong, Yao; Ma, Boxue; Ludtke, Steve; Chiu, Wah; Hartl, F Ulrich; Aebersold, Ruedi; Frydman, JudithStructure (London, England : 1993)2012 May 9814-2522503819
Protein misfolding and aggregation in cataract disease and prospects for prevention.Moreau, Kate L; King, Jonathan ATrends in molecular medicine2012 May273-8222520268
Quantum dot-fluorescent protein FRET probes for sensing intracellular pH.Dennis, Allison M; Rhee, Won Jong; Sotto, David; Dublin, Steven N; Bao, GangACS nano2012 Apr 242917-2422443420
SYNZIP protein interaction toolbox: in vitro and in vivo specifications of heterospecific coiled-coil interaction domains.Thompson, Kenneth Evan; Bashor, Caleb J; Lim, Wendell A; Keating, Amy EACS synthetic biology2012 Apr 20118-2922558529
Evaluation of end-capped DNA modules for pRNA capture and functionalization.Laing, Brian M; Bergstrom, Donald EBioconjugate chemistry2012 Apr 18683-722443238
Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.Kapp, Gregory T; Liu, Sen; Stein, Amelie; Wong, Derek T; Remenyi, Attila; Yeh, Brian J; Fraser, James S; Taunton, Jack; Lim, Wendell A; Kortemme, TanjaProceedings of the National Academy of Sciences of the United States of America2012 Apr 35277-8222403064
Cells test substrate rigidity by local contractions on submicrometer pillars.Ghassemi, Saba; Meacci, Giovanni; Liu, Shuaimin; Gondarenko, Alexander A; Mathur, Anurag; Roca-Cusachs, Pere; Sheetz, Michael P; Hone, JamesProceedings of the National Academy of Sciences of the United States of America2012 Apr 35328-3322431603
Signaling at neuro/immune synapses.Dustin, Michael LThe Journal of clinical investigation2012 Apr 21149-5522466656
Rapid optical control of nociception with an ion-channel photoswitch.Mourot, Alexandre; Fehrentz, Timm; Le Feuvre, Yves; Smith, Caleb M; Herold, Christian; Dalkara, Deniz; Nagy, Frederic; Trauner, Dirk; Kramer, Richard HNature methods2012 Apr396-40222343342
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Assembly stoichiometry of the GluK2/GluK5 kainate receptor complex.Reiner, Andreas; Arant, Ryan J; Isacoff, Ehud YCell reports2012 Mar 29234-4022509486
Supramolecular non-amyloid intermediates in the early stages of ýý-synuclein aggregation.Fauerbach, Jonathan A; Yushchenko, Dmytro A; Shahmoradian, Sarah H; Chiu, Wah; Jovin, Thomas M; Jares-Erijman, Elizabeth ABiophysical journal2012 Mar 71127-3622404935
Constructing and validating initial Cýý models from subnanometer resolution density maps with pathwalking.Baker, Mariah R; Rees, Ian; Ludtke, Steven J; Chiu, Wah; Baker, Matthew LStructure (London, England : 1993)2012 Mar 7450-6322405004
Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency.Bammes, Benjamin E; Rochat, Ryan H; Jakana, Joanita; Chen, Dong-Hua; Chiu, WahJournal of structural biology2012 Mar589-60122285189
Optogenetic activation of LiGluR-expressing astrocytes evokes anion channel-mediated glutamate release.Li, Dongdong; Herault, Karine; Isacoff, Ehud Y; Oheim, Martin; Ropert, NicoleThe Journal of physiology2012 Feb 15855-7322219341
Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9.Dalkara, D; Byrne, L C; Lee, T; Hoffmann, N V; Schaffer, D V; Flannery, J GGene therapy2012 Feb176-8122011645
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Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors.Tochitsky, Ivan; Banghart, Matthew R; Mourot, Alexandre; Yao, Jennifer Z; Gaub, Benjamin; Kramer, Richard H; Trauner, DirkNature chemistry2012 Feb105-1122270644
Emergence of patterned activity in the developing zebrafish spinal cord.Warp, Erica; Agarwal, Gautam; Wyart, Claire; Friedmann, Drew; Oldfield, Claire S; Conner, Alden; Del Bene, Filippo; Arrenberg, Aristides B; Baier, Herwig; Isacoff, Ehud YCurrent biology : CB2012 Jan 2493-10222197243
Investigating how peptide length and a pathogenic mutation modify the structural ensemble of amyloid beta monomer.Lin, Yu-Shan; Bowman, Gregory R; Beauchamp, Kyle A; Pande, Vijay SBiophysical journal2012 Jan 18315-2422339868
Mechanosensing in T lymphocyte activation.Judokusumo, Edward; Tabdanov, Erdem; Kumari, Sudha; Dustin, Michael L; Kam, Lance CBiophysical journal2012 Jan 18L5-722339876
In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology.Tsai, Michelle; Kita, Ashley; Leach, Joseph; Rounsevell, Ross; Huang, James N; Moake, Joel; Ware, Russell E; Fletcher, Daniel A; Lam, Wilbur AThe Journal of clinical investigation2012 Jan 3408-1822156199
Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies.Russel, Daniel; Lasker, Keren; Webb, Ben; Velazquez-Muriel, Javier; Tjioe, Elina; Schneidman-Duhovny, Dina; Peterson, Bret; Sali, AndrejPLoS biology2012 Jane100124422272186
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Incorporation of noncanonical amino acids into Rosetta and use in computational protein-peptide interface design.Renfrew, P Douglas; Choi, Eun Jung; Bonneau, Richard; Kuhlman, BrianPloS one2012e3263722431978
Imaging of HIV-1 envelope-induced virological synapse and signaling on synthetic lipid bilayers.Prins, Kathleen C; Vasiliver-Shamis, Gaia; Cammer, Michael; Depoil, David; Dustin, Michael L; Hioe, Catarina EJournal of visualized experiments : JoVE2012NULL22433250
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Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity.Ding, Xianting; Sanchez, David Jesse; Shahangian, Arash; Al-Shyoukh, Ibrahim; Cheng, Genhong; Ho, Chih-MingInternational journal of nanomedicine20122281-9222654513
"Push through one-way valve" mechanism of viral DNA packaging.Zhang, Hui; Schwartz, Chad; De Donatis, Gian Marco; Guo, PeixuanAdvances in virus research2012415-6522748815
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A streamlined method for detecting structural variants in cancer genomes by short read paired-end sequencing.Mijuskovic, Martina; Brown, Stuart M; Tang, Zuojian; Lindsay, Cory R; Efstathiadis, Efstratios; Deriano, Ludovic; Roth, David BPloS one2012e4831423144753
Cellular inclusion bodies of mutant huntingtin exon 1 obscure small fibrillar aggregate species.Sahl, Steffen J; Weiss, Lucien E; Duim, Whitney C; Frydman, Judith; Moerner, W EScientific reports201289523193437
Accurate and Effective Live Bacteria Microarray Patterning on Thick Polycationic Polymer Layer Co-Patterned with HMDS.Wong, Ieong; Ding, Xianting; Wu, Chunsheng; Ho, Chih-MingRSC advances20127673-767623418622
Rapidly optimizing an aptamer based BoNT sensor by feedback system control (FSC) scheme.Wei, Fang; Bai, Bin; Ho, Chih-MingBiosensors & bioelectronics2011 Dec 15174-921993141
Shear flow-induced formation of tubular cell protrusions in multiple myeloma cells.Porat, Ziv; Yaron, Itamar; Katz, Ben-Zion; Kam, Zvi; Geiger, BenjaminJournal of cellular physiology2011 Dec3197-20721344380
Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing.Prager-Khoutorsky, Masha; Lichtenstein, Alexandra; Krishnan, Ramaswamy; Rajendran, Kavitha; Mayo, Avi; Kam, Zvi; Geiger, Benjamin; Bershadsky, Alexander DNature cell biology2011 Dec1457-6522081092
Homologous recombination-based gene therapy for the primary immunodeficiencies.Porteus, MatthewAnnals of the New York Academy of Sciences2011 Dec131-4022236437
Cellular mechanotransduction: filamin A strains to regulate motility.Lynch, Christopher D; Sheetz, Michael PCurrent biology : CB2011 Nov 22R916-822115457
Self-amplifying autocrine actions of BDNF in axon development.Cheng, Pei-Lin; Song, Ai-Hong; Wong, Yu-Hui; Wang, Sheng; Zhang, Xiang; Poo, Mu-MingProceedings of the National Academy of Sciences of the United States of America2011 Nov 818430-522025720
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution.Jiang, Yan; Douglas, Nicholai R; Conley, Nicholas R; Miller, Erik J; Frydman, Judith; Moerner, W EProceedings of the National Academy of Sciences of the United States of America2011 Oct 1116962-721896715
High-resolution imaging of the immunological synapse and T-cell receptor microclustering through microfabricated substrates.Biggs, M J P; Milone, M C; Santos, L C; Gondarenko, A; Wind, S JJournal of the Royal Society, Interface / the Royal Society2011 Oct 71462-7121490003
Inhibition of unfolding and aggregation of lens protein human gamma D crystallin by sodium citrate.Goulet, Daniel R; Knee, Kelly M; King, Jonathan AExperimental eye research2011 Oct371-8121600897
New insights into the T cell synapse from single molecule techniques.Dustin, Michael L; Depoil, DavidNature reviews. Immunology2011 Oct672-8421904389
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE.Qiu, Peng; Simonds, Erin F; Bendall, Sean C; Gibbs Jr, Kenneth D; Bruggner, Robert V; Linderman, Michael D; Sachs, Karen; Nolan, Garry P; Plevritis, Sylvia KNature biotechnology2011 Oct886-9121964415
An Information Theory Approach to Nonlinear, Nonequilibrium Thermodynamics.Rogers, David M; Beck, Thomas L; Rempe, Susan BJournal of statistical physics2011 Oct385-40922966210
A novel method for producing mono-biotinylated, biologically active neurotrophic factors: an essential reagent for single molecule study of axonal transport.Sung, Kijung; Maloney, Michael T; Yang, Jingkun; Wu, ChengbiaoJournal of neuroscience methods2011 Sep 15121-821756937
Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange.Tong, Sheng; Hou, Sijian; Ren, Binbin; Zheng, Zhilan; Bao, GangNano letters2011 Sep 143720-621793503
Sub-diffraction imaging of huntingtin protein aggregates by fluorescence blink-microscopy and atomic force microscopy.Duim, Whitney C; Chen, Bryan; Frydman, Judith; Moerner, W EChemphyschem : a European journal of chemical physics and physical chemistry2011 Sep 122387-9021735512
Rapid, massively parallel single-cell drug response measurements via live cell interferometry.Reed, Jason; Chun, Jennifer; Zangle, Thomas A; Kalim, Sheraz; Hong, Jason S; Pefley, Sarah E; Zheng, Xin; Gimzewski, James K; Teitell, Michael ABiophysical journal2011 Sep 71025-3121889438
AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa.Dalkara, Deniz; Kolstad, Kathleen D; Guerin, Karen I; Hoffmann, Natalie V; Visel, Meike; Klimczak, Ryan R; Schaffer, David V; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2011 Sep1602-821522134
Practical performance evaluation of a 10k ýý 10k CCD for electron cryo-microscopy.Bammes, Benjamin E; Rochat, Ryan H; Jakana, Joanita; Chiu, WahJournal of structural biology2011 Sep384-9321619932
Developing defined culture systems for human pluripotent stem cells.Valamehr, Bahram; Tsutsui, Hideaki; Ho, Chih-Ming; Wu, HongRegenerative medicine2011 Sep623-3421916597
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.Porter, David L; Levine, Bruce L; Kalos, Michael; Bagg, Adam; June, Carl HThe New England journal of medicine2011 Aug 25725-3321830940
Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.Alhamadsheh, Mamoun M; Connelly, Stephen; Cho, Ahryon; Reixach, Natalia; Powers, Evan T; Pan, Dorothy W; Wilson, Ian A; Kelly, Jeffery W; Graef, Isabella AScience translational medicine2011 Aug 2497ra8121865539
Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array.Wang, Sheng; Ota, Sadao; Guo, Bin; Ryu, Jongeun; Rhodes, Christopher; Xiong, Yi; Kalim, Sheraz; Zeng, Li; Chen, Yong; Teitell, Michael A; Zhang, XiangNano letters2011 Aug 103431-421780816
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia.Kalos, Michael; Levine, Bruce L; Porter, David L; Katz, Sharyn; Grupp, Stephan A; Bagg, Adam; June, Carl HScience translational medicine2011 Aug 1095ra7321832238
Lipid bilayer coated Al(2)O(3) nanopore sensors: towards a hybrid biological solid-state nanopore.Venkatesan, Bala Murali; Polans, James; Comer, Jeffrey; Sridhar, Supriya; Wendell, David; Aksimentiev, Aleksei; Bashir, RashidBiomedical microdevices2011 Aug671-8221487665
Biogenesis and function of nuclear bodies.Mao, Yuntao S; Zhang, Bin; Spector, David LTrends in genetics : TIG2011 Aug295-30621680045
PKC-ýý function at the immunological synapse: prospects for therapeutic targeting.Zanin-Zhorov, Alexandra; Dustin, Michael L; Blazar, Bruce RTrends in immunology2011 Aug358-6321733754
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.Meiler, Steffen E; Wade, Marlene; Kutlar, Ferdane; Yerigenahally, Shobha D; Xue, Yongjun; Moutouh-de Parseval, Laure A; Corral, Laura G; Swerdlow, Paul S; Kutlar, AbdullahBlood2011 Jul 281109-1221536862
Probing the thermodynamics of competitive ion binding using minimum energy structures.Rogers, David M; Rempe, Susan BThe journal of physical chemistry. B2011 Jul 289116-2921721551
Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles.Ashley, Carlee E; Carnes, Eric C; Phillips, Genevieve K; Durfee, Paul N; Buley, Mekensey D; Lino, Christopher A; Padilla, David P; Phillips, Brandy; Carter, Mark B; Willman, Cheryl L; Brinker, C Jeffrey; Caldeira, Jerri do Carmo; Chackerian, Bryce; WhartoACS nano2011 Jul 265729-4521615170
Sampling multiple scoring functions can improve protein loop structure prediction accuracy.Li, Yaohang; Rata, Ionel; Jakobsson, EricJournal of chemical information and modeling2011 Jul 251656-6621702492
Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade.French, Christopher T; Toesca, Isabelle J; Wu, Ting-Hsiang; Teslaa, Tara; Beaty, Shannon M; Wong, Wayne; Liu, Minghsun; Schroder, Imke; Chiou, Pei-Yu; Teitell, Michael A; Miller, Jeff FProceedings of the National Academy of Sciences of the United States of America2011 Jul 1912095-10021730143
Omnidirectional 3D nanoplasmonic optical antenna array via soft-matter transformation.Ross, Benjamin M; Wu, Liz Y; Lee, Luke PNano letters2011 Jul 132590-521661733
Optogenetic photochemical control of designer K+ channels in mammalian neurons.Fortin, Doris L; Dunn, Timothy W; Fedorchak, Alexis; Allen, Duane; Montpetit, Rachel; Banghart, Matthew R; Trauner, Dirk; Adelman, John P; Kramer, Richard HJournal of neurophysiology2011 Jul488-9621525363
LiGluR restores visual responses in rodent models of inherited blindness.Caporale, Natalia; Kolstad, Kathleen D; Lee, Trevor; Tochitsky, Ivan; Dalkara, Deniz; Trauner, Dirk; Kramer, Richard; Dan, Yang; Isacoff, Ehud Y; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2011 Jul1212-921610698
MultiFit: a web server for fitting multiple protein structures into their electron microscopy density map.Tjioe, Elina; Lasker, Keren; Webb, Ben; Wolfson, Haim J; Sali, AndrejNucleic acids research2011 JulW167-7021715383
Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase.Won, Angela P; Garbarino, Joan E; Lim, Wendell AProceedings of the National Academy of Sciences of the United States of America2011 Jun 149809-1421628578
Optimized method for the synthesis and purification of adenosine--folic acid conjugates for use as transcription initiators in the preparation of modified RNA.Laing, Brian M; Guo, Peixuan; Bergstrom, Donald EMethods (San Diego, Calif.)2011 Jun260-621163352
Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition.Zhou, Jiehua; Shu, Yi; Guo, Peixuan; Smith, David D; Rossi, John JMethods (San Diego, Calif.)2011 Jun284-9421256218
Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis.Li, S Kevin; Liddell, Mark R; Wen, HeJournal of pharmaceutical and biomedical analysis2011 Jun 1603-721269789
Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells.Shu, Yi; Cinier, Mathieu; Shu, Dan; Guo, PeixuanMethods (San Diego, Calif.)2011 Jun204-1421320601
Engineering light-regulated ion channels.Fortin, Doris L; Dunn, Timothy W; Kramer, Richard HCold Spring Harbor protocols2011 Jun579-8521632787
Selective biomolecular nanoarrays for parallel single-molecule investigations.Palma, Matteo; Abramson, Justin J; Gorodetsky, Alon A; Penzo, Erika; Gonzalez Jr, Ruben L; Sheetz, Michael P; Nuckolls, Colin; Hone, James; Wind, Shalom JJournal of the American Chemical Society2011 May 257656-921528859
A boost for the emerging field of RNA nanotechnology.Shukla, Girish C; Haque, Farzin; Tor, Yitzhak; Wilhelmsson, L Marcus; Toulme, Jean-Jacques; Isambert, Herve; Guo, Peixuan; Rossi, John J; Tenenbaum, Scott A; Shapiro, Bruce AACS nano2011 May 243405-1821604810
Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.Zhang, Junjie; Ma, Boxue; DiMaio, Frank; Douglas, Nicholai R; Joachimiak, Lukasz A; Baker, David; Frydman, Judith; Levitt, Michael; Chiu, WahStructure (London, England : 1993)2011 May 11633-921565698
Scaffold proteins: hubs for controlling the flow of cellular information.Good, Matthew C; Zalatan, Jesse G; Lim, Wendell AScience (New York, N.Y.)2011 May 6680-621551057
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.Bendall, Sean C; Simonds, Erin F; Qiu, Peng; Amir, El-ad D; Krutzik, Peter O; Finck, Rachel; Bruggner, Robert V; Melamed, Rachel; Trejo, Angelica; Ornatsky, Olga I; Balderas, Robert S; Plevritis, Sylvia K; Sachs, Karen; Pe'er, Dana; Tanner, Scott D; NolanScience (New York, N.Y.)2011 May 6687-9621551058
Regulation of cell differentiation by the DNA damage response.Sherman, Mara H; Bassing, Craig H; Teitell, Michael ATrends in cell biology2011 May312-921354798
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Molecular architecture and function of matrix adhesions.Geiger, Benjamin; Yamada, Kenneth MCold Spring Harbor perspectives in biology2011 MayNULL21441590
Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells.Hoffmann, Sabrina; Hosseini, Babak H; Hecker, Markus; Louban, Ilia; Bulbuc, Nadja; Garbi, Natalio; Wabnitz, Guido H; Samstag, Yvonne; Spatz, Joachim P; Hammerling, Gunter JImmunology letters2011 Apr 3013-2021112354
Tricontinuous Cubic Nanostructure and Pore Size Patterning in Mesostructured Silica Films Templated with Glycerol Monooleate.Dunphy, Darren R; Garcia, Fred L; Kaehr, Bryan; Khripin, Constantine Y; Collord, Andrew D; Baca, Helen K; Tate, Michael P; Hillhouse, Hugh W; Strzalka, Joseph W; Jiang, Zhang; Wang, Jin; Brinker, C JeffreyChemistry of materials : a publication of the American Chemical Society2011 Apr 262107-211221572556
Optical control of calcium affinity in a spiroamido-rhodamine based calcium chelator.Wu, Liangxing; Dai, Yingrui; Marriott, GerardOrganic letters2011 Apr 152018-2121417245
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A unified platform for optoelectrowetting and optoelectronic tweezers.Valley, Justin K; Pei, Shao Ning; Ningpei, Shao; Jamshidi, Arash; Hsu, Hsan-Yin; Wu, Ming CLab on a chip2011 Apr 71292-721311817
Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion.Kim, Il-Han; Chen, Yi-Chun M; Spector, David L; Eils, Roland; Rohr, KarlIEEE transactions on image processing : a publication of the IEEE Signal Processing Society2011 Apr1011-2220840894
Intravitreal injection of AAV2 transduces macaque inner retina.Yin, Lu; Greenberg, Kenneth; Hunter, Jennifer J; Dalkara, Deniz; Kolstad, Kathleen D; Masella, Benjamin D; Wolfe, Robert; Visel, Meike; Stone, Daniel; Libby, Richard T; Diloreto Jr, David; Schaffer, David; Flannery, John; Williams, David R; Merigan, WilliInvestigative ophthalmology & visual science2011 Apr2775-8321310920
Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons.Peled, Einat S; Isacoff, Ehud YNature neuroscience2011 Apr519-2621378971
Normal modes of prion proteins: from native to infectious particle.Samson, Abraham O; Levitt, MichaelBiochemistry2011 Mar 292243-821338080
High-speed droplet generation on demand driven by pulse laser-induced cavitation.Park, Sung-Yong; Wu, Ting-Hsiang; Chen, Yue; Teitell, Michael A; Chiou, Pei-YuLab on a chip2011 Mar 211010-221290045
Nanochromatography driven by the coffee ring effect.Wong, Tak-Sing; Chen, Ting-Hsuan; Shen, Xiaoying; Ho, Chih-MingAnalytical chemistry2011 Mar 151871-321288015
Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level.Schvartzman, Mark; Palma, Matteo; Sable, Julia; Abramson, Justin; Hu, Xian; Sheetz, Michael P; Wind, Shalom JNano letters2011 Mar 91306-1221319842
Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells.Ha, Kyungsoo; Takeda, Yoshihiko; Dynan, William SDNA repair2011 Mar 7252-921144806
The RAG2 C terminus suppresses genomic instability and lymphomagenesis.Deriano, Ludovic; Chaumeil, Julie; Coussens, Marc; Multani, Asha; Chou, YiFan; Alekseyenko, Alexander V; Chang, Sandy; Skok, Jane A; Roth, David BNature2011 Mar 3119-2321368836
Macromolecular docking restrained by a small angle X-ray scattering profile.Schneidman-Duhovny, Dina; Hammel, Michal; Sali, AndrejJournal of structural biology2011 Mar461-7120920583
Cell-directed-assembly: directing the formation of nano/bio interfaces and architectures with living cells.Baca, Helen K; Carnes, Eric C; Ashley, Carlee E; Lopez, DeAnna M; Douthit, Cynthia; Karlin, Shelly; Brinker, C JeffreyBiochimica et biophysica acta2011 Mar259-6720933574
Translating the lessons from gene therapy to the development of regenerative medicine.Porteus, MatthewMolecular therapy : the journal of the American Society of Gene Therapy2011 Mar439-4121358706
Construction of a genetic multiplexer to toggle between chemosensory pathways in Escherichia coli.Moon, Tae Seok; Clarke, Elizabeth J; Groban, Eli S; Tamsir, Alvin; Clark, Ryan M; Eames, Matthew; Kortemme, Tanja; Voigt, Christopher AJournal of molecular biology2011 Feb 18215-2721185306
Photothermal nanoblade for large cargo delivery into mammalian cells.Wu, Ting-Hsiang; Teslaa, Tara; Kalim, Sheraz; French, Christopher T; Moghadam, Shahriar; Wall, Randolph; Miller, Jeffery F; Witte, Owen N; Teitell, Michael A; Chiou, Pei-YuAnalytical chemistry2011 Feb 151321-721247066
Rational design, synthesis, and characterization of highly fluorescent optical switches for high-contrast optical lock-in detection (OLID) imaging microscopy in living cells.Petchprayoon, Chutima; Yan, Yuling; Mao, Shu; Marriott, GerardBioorganic & medicinal chemistry2011 Feb 11030-4020674372
Nuclear speckles.Spector, David L; Lamond, Angus ICold Spring Harbor perspectives in biology2011 Feb20926517
Application of phi29 motor pRNA for targeted therapeutic delivery of siRNA silencing metallothionein-IIA and survivin in ovarian cancers.Tarapore, Pheruza; Shu, Yi; Guo, Peixuan; Ho, Shuk-MeiMolecular therapy : the journal of the American Society of Gene Therapy2011 Feb386-9421063391
New developments in the induction and antiviral effectors of type I interferon.Liu, Su-Yang; Sanchez, David Jesse; Cheng, GenhongCurrent opinion in immunology2011 Feb57-6421123041
Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus.Chen, Dong-Hua; Baker, Matthew L; Hryc, Corey F; DiMaio, Frank; Jakana, Joanita; Wu, Weimin; Dougherty, Matthew; Haase-Pettingell, Cameron; Schmid, Michael F; Jiang, Wen; Baker, David; King, Jonathan A; Chiu, WahProceedings of the National Academy of Sciences of the United States of America2011 Jan 251355-6021220301
An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells.Tsutsui, Hideaki; Valamehr, Bahram; Hindoyan, Antreas; Qiao, Rong; Ding, Xianting; Guo, Shuling; Witte, Owen N; Liu, Xin; Ho, Chih-Ming; Wu, HongNature communications2011 Jan 2516721266967
Dual action of ATP hydrolysis couples lid closure to substrate release into the group II chaperonin chamber.Douglas, Nicholai R; Reissmann, Stefanie; Zhang, Junjie; Chen, Bo; Jakana, Joanita; Kumar, Ramya; Chiu, Wah; Frydman, JudithCell2011 Jan 21240-5221241893
Multichromatic control of gene expression in Escherichia coli.Tabor, Jeffrey J; Levskaya, Anselm; Voigt, Christopher AJournal of molecular biology2011 Jan 14315-2421035461
Bright and compact alloyed quantum dots with broadly tunable near-infrared absorption and fluorescence spectra through mercury cation exchange.Smith, Andrew M; Nie, ShumingJournal of the American Chemical Society2011 Jan 1224-621142154
Statistical method for revealing form-function relations in biological networks.Mugler, Andrew; Grinshpun, Boris; Franks, Riley; Wiggins, Chris HProceedings of the National Academy of Sciences of the United States of America2011 Jan 11446-5121183719
Molecular rearrangements involved in the capsid shell maturation of bacteriophage T7.Ionel, Alina; Velazquez-Muriel, Javier A; Luque, Daniel; Cuervo, Ana; Caston, Jose R; Valpuesta, Jose M; Martin-Benito, Jaime; Carrascosa, Jose LThe Journal of biological chemistry2011 Jan 7234-4220962334
The group II chaperonin Mm-Cpn binds and refolds human ýýD crystallin.Knee, Kelly M; Goulet, Daniel R; Zhang, Junjie; Chen, Bo; Chiu, Wah; King, Jonathan AProtein science : a publication of the Protein Society2011 Jan30-4120981710
Oxidative stress induces reactivation of Kaposi's sarcoma-associated herpesvirus and death of primary effusion lymphoma cells.Li, Xudong; Feng, Jiaying; Sun, RenJournal of virology2011 Jan715-2421068240
The promise of optogenetics in cell biology: interrogating molecular circuits in space and time.Toettcher, Jared E; Voigt, Christopher A; Weiner, Orion D; Lim, Wendell ANature methods2011 Jan35-821191370
A modern ionotropic glutamate receptor with a K(+) selectivity signature sequence.Janovjak, H; Sandoz, G; Isacoff, E YNature communications201123221407198
Systematic quantitative characterization of cellular responses induced by multiple signals.Al-Shyoukh, Ibrahim; Yu, Fuqu; Feng, Jiaying; Yan, Karen; Dubinett, Steven; Ho, Chih-Ming; Shamma, Jeff S; Sun, RenBMC systems biology20118821624115
Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.Palma, Matteo; Abramson, Justin J; Gorodetsky, Alon A; Nuckolls, Colin; Sheetz, Michael P; Wind, Shalom J; Hone, JamesMethods in molecular biology (Clifton, N.J.)2011169-8521674372
Modeling of proteins and their assemblies with the integrative modeling platform.Webb, Benjamin; Lasker, Keren; Schneidman-Duhovny, Dina; Tjioe, Elina; Phillips, Jeremy; Kim, Seung Joong; Velazquez-Muriel, Javier; Russel, Daniel; Sali, AndrejMethods in molecular biology (Clifton, N.J.)2011377-9721877292
Control of Kaposi's sarcoma-associated herpesvirus reactivation induced by multiple signals.Yu, Fuqu; Al-Shyoukh, Ibrahim; Feng, Jiaying; Li, Xudong; Liao, Chia Wei; Ho, Chih-Ming; Shamma, Jeff S; Sun, RenPloS one2011e2099821904595
Light-based feedback for controlling intracellular signaling dynamics.Toettcher, Jared E; Gong, Delquin; Lim, Wendell A; Weiner, Orion DNature methods2011837-921909100
Miniaturized integration of a fluorescence microscope.Ghosh, Kunal K; Burns, Laurie D; Cocker, Eric D; Nimmerjahn, Axel; Ziv, Yaniv; Gamal, Abbas El; Schnitzer, Mark JNature methods2011871-821909102
Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level.Kita, Ashley; Sakurai, Yumiko; Myers, David R; Rounsevell, Ross; Huang, James N; Seok, Tae Joon; Yu, Kyoungsik; Wu, Ming C; Fletcher, Daniel A; Lam, Wilbur APloS one2011e2643722028878
Luminescent nanocrystal stress gauge.Choi, Charina L; Koski, Kristie J; Olson, Andrew C K; Alivisatos, A PaulProceedings of the National Academy of Sciences of the United States of America2010 Dec 1421306-1021098301
Motile and non-motile sperm diagnostic manipulation using optoelectronic tweezers.Ohta, Aaron T; Garcia, Maurice; Valley, Justin K; Banie, Lia; Hsu, Hsan-Yin; Jamshidi, Arash; Neale, Steven L; Lue, Tom; Wu, Ming CLab on a chip2010 Dec 73213-720835428
Efficient dielectrophoretic patterning of embryonic stem cells in energy landscapes defined by hydrogel geometries.Tsutsui, Hideaki; Yu, Edmond; Marquina, Sabrina; Valamehr, Bahram; Wong, Ieong; Wu, Hong; Ho, Chih-MingAnnals of biomedical engineering2010 Dec3777-8820614250
SIMULATION OF ION CONDUCTION IN ýý-HEMOLYSIN NANOPORES WITH COVALENTLY ATTACHED ýý-CYCLODEXTRIN BASED ON BOLTZMANN TRANSPORT MONTE CARLO MODEL.Toghraee, Reza; Lee, Kyu-Il; Papke, David; Chiu, See-Wing; Jakobsson, Eric; Ravaioli, UmbertoJournal of computational and theoretical nanoscience2010 Dec2555-256720938493
A noninvasive, motility independent, sperm sorting method and technology to identify and retrieve individual viable nonmotile sperm for intracytoplasmic sperm injection.Garcia, Maurice M; Ohta, Aaron T; Walsh, Thomas J; Vittinghof, Eric; Lin, Guiting; Wu, Ming C; Lue, Tom FThe Journal of urology2010 Dec2466-7220952004
The emerging field of RNA nanotechnology.Guo, PeixuanNature nanotechnology2010 Dec833-4221102465
Focal adhesions in osteoneogenesis.Biggs, M J P; Dalby, M JProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine2010 Dec1441-5321287830
Determining macromolecular assembly structures by molecular docking and fitting into an electron density map.Lasker, Keren; Sali, Andrej; Wolfson, Haim JProteins2010 Nov 153205-1120827723
Pseudomonas aeruginosa Homoserine lactone activates store-operated cAMP and cystic fibrosis transmembrane regulator-dependent Cl- secretion by human airway epithelia.Schwarzer, Christian; Wong, Steven; Shi, James; Matthes, Elizabeth; Illek, Beate; Ianowski, Juan P; Arant, Ryan J; Isacoff, Ehud; Vais, Horia; Foskett, J Kevin; Maiellaro, Isabella; Hofer, Aldebaran M; Machen, Terry EThe Journal of biological chemistry2010 Nov 534850-6320739289
Filtering of visual information in the tectum by an identified neural circuit.Del Bene, Filippo; Wyart, Claire; Robles, Estuardo; Tran, Amanda; Looger, Loren; Scott, Ethan K; Isacoff, Ehud Y; Baier, HerwigScience (New York, N.Y.)2010 Oct 29669-7321030657
Photothermal nanoblade for patterned cell membrane cutting.Wu, Ting-Hsiang; Teslaa, Tara; Teitell, Michael A; Chiou, Pei-YuOptics express2010 Oct 2523153-6021164656
An agar gel membrane-PDMS hybrid microfluidic device for long term single cell dynamic study.Wong, Ieong; Atsumi, Shota; Huang, Wei-Chih; Wu, Tung-Yun; Hanai, Taizo; Lam, Miu-Ling; Tang, Ping; Yang, Jian; Liao, James C; Ho, Chih-MingLab on a chip2010 Oct 212710-920664845
Workshop on molecular animation.Bromberg, Sarina; Chiu, Wah; Ferrin, Thomas EStructure (London, England : 1993)2010 Oct 131261-520947014
A new strategy to photoactivate green fluorescent protein.Groff, Dan; Wang, Feng; Jockusch, Steffen; Turro, Nicholas J; Schultz, Peter GAngewandte Chemie (International ed. in English)2010 Oct 117677-920836111
Nanotopographical modification: a regulator of cellular function through focal adhesions.Biggs, Manus Jonathan Paul; Richards, R Geoff; Dalby, Matthew JNanomedicine : nanotechnology, biology, and medicine2010 Oct619-3320138244
Robust properties of membrane-embedded connector channel of bacterial virus phi29 DNA packaging motor.Jing, Peng; Haque, Farzin; Vonderheide, Anne P; Montemagno, Carlo; Guo, PeixuanMolecular bioSystems2010 Oct1844-5220523933
Scanless two-photon excitation of channelrhodopsin-2.Papagiakoumou, Eirini; Anselmi, Francesca; Begue, Aurelien; de Sars, Vincent; Gluckstad, Jesper; Isacoff, Ehud Y; Emiliani, ValentinaNature methods2010 Oct848-5420852649
Nanotechnology in ophthalmology.Zarbin, Marco A; Montemagno, Carlo; Leary, James F; Ritch, RobertCanadian journal of ophthalmology. Journal canadien d'ophtalmologie2010 Oct457-7620871642
Nanoplasmonic gene regulation.Lee, Somin Eunice; Lee, Luke PCurrent opinion in chemical biology2010 Oct623-3320888286
Safe and effective synthetic biology.LaVan, David A; Marmon, Louis MNature biotechnology2010 Oct1010-220944581
AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling.Sherman, Mara H; Kuraishy, Ali I; Deshpande, Chetan; Hong, Jason S; Cacalano, Nicholas A; Gatti, Richard A; Manis, John P; Damore, Michael A; Pellegrini, Matteo; Teitell, Michael AMolecular cell2010 Sep 24873-8520864035
One-way traffic of a viral motor channel for double-stranded DNA translocation.Jing, Peng; Haque, Farzin; Shu, Dan; Montemagno, Carlo; Guo, PeixuanNano letters2010 Sep 83620-720722407
miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate.Mann, Mati; Barad, Omer; Agami, Reuven; Geiger, Benjamin; Hornstein, EranProceedings of the National Academy of Sciences of the United States of America2010 Sep 715804-920720163
Crystal structures of a group II chaperonin reveal the open and closed states associated with the protein folding cycle.Pereira, Jose H; Ralston, Corie Y; Douglas, Nicholai R; Meyer, Daniel; Knee, Kelly M; Goulet, Daniel R; King, Jonathan A; Frydman, Judith; Adams, Paul DThe Journal of biological chemistry2010 Sep 327958-6620573955
Phosphotyrosine signaling: evolving a new cellular communication system.Lim, Wendell A; Pawson, TonyCell2010 Sep 3661-720813250
Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair.Hirsch, M L; Green, L; Porteus, M H; Samulski, R JGene therapy2010 Sep1175-8020463753
Action of the chaperonin GroEL/ES on a non-native substrate observed with single-molecule FRET.Kim, So Yeon; Miller, Erik J; Frydman, Judith; Moerner, W EJournal of molecular biology2010 Aug 27553-6320600107
Alternative splicing of neuroligin regulates the rate of presynaptic differentiation.Lee, Hanson; Dean, Camin; Isacoff, EhudThe Journal of neuroscience : the official journal of the Society for Neuroscience2010 Aug 2511435-4620739565
SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane.Lauffer, Benjamin E L; Melero, Cristina; Temkin, Paul; Lei, Cai; Hong, Wanjin; Kortemme, Tanja; von Zastrow, MarkThe Journal of cell biology2010 Aug 23565-7420733053
Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing.Moore, Simon W; Roca-Cusachs, Pere; Sheetz, Michael PDevelopmental cell2010 Aug 17194-20620708583
Oriented Insertion of phi29 N-Hexahistidine-tagged gp10 Connector Protein Assemblies into C(20)BAS Bolalipid Membrane Vesicles.Hyun, Seok-Hee; Kim, Hee-Kwon; Kim, Jong-Mok; Thompson, David HJournal of the American Chemical Society2010 Aug 1720715817
Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions.Murata, Kazuyoshi; Liu, Xiangan; Danev, Radostin; Jakana, Joanita; Schmid, Michael F; King, Jonathan; Nagayama, Kuniaki; Chiu, WahStructure (London, England : 1993)2010 Aug 11903-1220696391
Cell spreading as a hydrodynamic process.Fardin, M A; Rossier, O M; Rangamani, P; Avigan, P D; Gauthier, N C; Vonnegut, W; Mathur, A; Hone, J; Iyengar, R; Sheetz, M PSoft matter2010 Aug 104788-479923908673
Partially folded aggregation intermediates of human gammaD-, gammaC-, and gammaS-crystallin are recognized and bound by human alphaB-crystallin chaperone.Acosta-Sampson, Ligia; King, JonathanJournal of molecular biology2010 Aug 6134-5220621668
PNPASE regulates RNA import into mitochondria.Wang, Geng; Chen, Hsiao-Wen; Oktay, Yavuz; Zhang, Jin; Allen, Eric L; Smith, Geoffrey M; Fan, Kelly C; Hong, Jason S; French, Samuel W; McCaffery, J Michael; Lightowlers, Robert N; Morse 3rd, Herbert C; Koehler, Carla M; Teitell, Michael ACell2010 Aug 6456-6720691904
Toward an integrated structural model of the 26S proteasome.Forster, Friedrich; Lasker, Keren; Nickell, Stephan; Sali, Andrej; Baumeister, WolfgangMolecular & cellular proteomics : MCP2010 Aug1666-7720467039
Use of a microscope stage-mounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response.Cao, Zhen; Kuhne, Wendy W; Steeb, Jennifer; Merkley, Mark A; Zhou, Yunfeng; Janata, Jiri; Dynan, William SNucleic acids research2010 Auge14420484377
Integrative structure modeling of macromolecular assemblies from proteomics data.Lasker, Keren; Phillips, Jeremy L; Russel, Daniel; Velazquez-Muriel, Javier; Schneidman-Duhovny, Dina; Tjioe, Elina; Webb, Ben; Schlessinger, Avner; Sali, AndrejMolecular & cellular proteomics : MCP2010 Aug1689-70220507923
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing.Janovjak, Harald; Szobota, Stephanie; Wyart, Claire; Trauner, Dirk; Isacoff, Ehud YNature neuroscience2010 Aug1027-3220581843
Nanomedicine in ophthalmology: the new frontier.Zarbin, Marco A; Montemagno, Carlo; Leary, James F; Ritch, RobertAmerican journal of ophthalmology2010 Aug144-162.e220670739
Biomolecular plasmonics for quantitative biology and nanomedicine.Lee, Somin Eunice; Lee, Luke PCurrent opinion in biotechnology2010 Aug489-9720801636
Information-optimal transcriptional response to oscillatory driving.Mugler, Andrew; Walczak, Aleksandra M; Wiggins, Chris HPhysical review letters2010 Jul 305810120867954
Surface ligand effects on metal-affinity coordination to quantum dots: implications for nanoprobe self-assembly.Dennis, Allison M; Sotto, David C; Mei, Bing C; Medintz, Igor L; Mattoussi, Hedi; Bao, GangBioconjugate chemistry2010 Jul 211160-7020568725
Continuous sorting of heterogeneous-sized embryoid bodies.Lillehoj, Peter B; Tsutsui, Hideaki; Valamehr, Bahram; Wu, Hong; Ho, Chih-MingLab on a chip2010 Jul 71678-8220376391
Single-sided continuous optoelectrowetting (SCOEW) for droplet manipulation with light patterns.Park, Sung-Yong; Teitell, Michael A; Chiou, Eric P YLab on a chip2010 Jul 71655-6120448870
RosettaBackrub--a web server for flexible backbone protein structure modeling and design.Lauck, Florian; Smith, Colin A; Friedland, Gregory F; Humphris, Elisabeth L; Kortemme, TanjaNucleic acids research2010 JulW569-7520462859
FoXS: a web server for rapid computation and fitting of SAXS profiles.Schneidman-Duhovny, Dina; Hammel, Michal; Sali, AndrejNucleic acids research2010 JulW540-420507903
Placement of alkanethiol-capped Au nanoparticles using organic solvents.Yim, Tae-Jin; Choi, Hyeunseok; Zhang, XiangJournal of colloid and interface science2010 Jun 117-2220332051
Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions.Pintilie, Grigore D; Zhang, Junjie; Goddard, Thomas D; Chiu, Wah; Gossard, David CJournal of structural biology2010 Jun427-3820338243
Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease.Connelly, Jon P; Barker, Jenny C; Pruett-Miller, Shondra; Porteus, Matthew HMolecular therapy : the journal of the American Society of Gene Therapy2010 Jun1103-1020389291
An information-theoretic derivation of min-cut-based clustering.Raj, Anil; Wiggins, Chris HIEEE transactions on pattern analysis and machine intelligence2010 Jun988-9520431126
Designing customized cell signalling circuits.Lim, Wendell ANature reviews. Molecular cell biology2010 Jun393-40320485291
Imaging dynamic cellular events with quantum dots The bright future.Smith, Andrew M; Wen, Mary M; Nie, ShumingThe biochemist2010 Jun 11220824157
Mechanisms controlling cell size and shape during isotropic cell spreading.Xiong, Yuguang; Rangamani, Padmini; Fardin, Marc-Antoine; Lipshtat, Azi; Dubin-Thaler, Benjamin; Rossier, Olivier; Sheetz, Michael P; Iyengar, RaviBiophysical journal2010 May 192136-4620483321
Lateral shear forces applied to cells with single elastic micropillars to influence focal adhesion dynamics.Heil, Patrick; Spatz, Joachim PJournal of physics. Condensed matter : an Institute of Physics journal2010 May 1919410821386435
Probing cellular traction forces by micropillar arrays: contribution of substrate warping to pillar deflection.Schoen, Ingmar; Hu, Wei; Klotzsch, Enrico; Vogel, ViolaNano letters2010 May 121823-3020387859
DNA diagnostics: nanotechnology-enhanced electrochemical detection of nucleic acids.Wei, Fang; Lillehoj, Peter B; Ho, Chih-MingPediatric research2010 May458-6820075759
The switchable integrin adhesome.Zaidel-Bar, Ronen; Geiger, BenjaminJournal of cell science2010 May 11385-820410370
Cytotoxic immunological synapses.Dustin, Michael L; Long, Eric OImmunological reviews2010 May24-3420536553
Engineering RNA for targeted siRNA delivery and medical application.Guo, Peixuan; Coban, Oana; Snead, Nicholas M; Trebley, Joe; Hoeprich, Steve; Guo, Songchuan; Shu, YiAdvanced drug delivery reviews2010 Apr 30650-6620230868
Minimal size of coffee ring structure.Shen, Xiaoying; Ho, Chih-Ming; Wong, Tak-SingThe journal of physical chemistry. B2010 Apr 295269-7420353247
Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster.Vardhana, Santosha; Choudhuri, Kaushik; Varma, Rajat; Dustin, Michael LImmunity2010 Apr 23531-4020399684
DNA Sensing using Nano-crystalline Surface Enhanced Al(2)O(3) Nanopore Sensors.Venkatesan, B M; Shah, A B; Zuo, J M; Bashir, RAdvanced functional materials2010 Apr 231266-127523335871
Super-resolution biomolecular crystallography with low-resolution data.Schroder, Gunnar F; Levitt, Michael; Brunger, Axel TNature2010 Apr 221218-2220376006
A biophysical model for integration of electrical, osmotic, and pH regulation in the human bronchial epithelium.Falkenberg, Cibele V; Jakobsson, EricBiophysical journal2010 Apr 211476-8520409466
Protein kinase C-theta mediates negative feedback on regulatory T cell function.Zanin-Zhorov, Alexandra; Ding, Yi; Kumari, Sudha; Attur, Mukundan; Hippen, Keli L; Brown, Maryanne; Blazar, Bruce R; Abramson, Steven B; Lafaille, Juan J; Dustin, Michael LScience (New York, N.Y.)2010 Apr 16372-620339032
Rapid diversification of cell signaling phenotypes by modular domain recombination.Peisajovich, Sergio G; Garbarino, Joan E; Wei, Ping; Lim, Wendell AScience (New York, N.Y.)2010 Apr 16368-7220395511
The kinetics of force-induced cell reorganization depend on microtubules and actin.Goldyn, Alexandra M; Kaiser, Peter; Spatz, Joachim P; Ballestrem, Christoph; Kemkemer, RalfCytoskeleton (Hoboken, N.J.)2010 Apr241-5020191565
Charge, hydrophobicity, and confined water: putting past simulations into a simple theoretical framework.England, Jeremy L; Pande, Vijay SBiochemistry and cell biology = Biochimie et biologie cellulaire2010 Apr359-6920453936
Force generated by actomyosin contraction builds bridges between adhesive contacts.Rossier, Olivier M; Gauthier, Nils; Biais, Nicolas; Vonnegut, Wynn; Fardin, Marc-Antoine; Avigan, Philip; Heller, Evan R; Mathur, Anurag; Ghassemi, Saba; Koeckert, Michael S; Hone, James C; Sheetz, Michael PThe EMBO journal2010 Mar 171055-6820150894
4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.Cong, Yao; Baker, Matthew L; Jakana, Joanita; Woolford, David; Miller, Erik J; Reissmann, Stefanie; Kumar, Ramya N; Redding-Johanson, Alyssa M; Batth, Tanveer S; Mukhopadhyay, Aindrila; Ludtke, Steven J; Frydman, Judith; Chiu, WahProceedings of the National Academy of Sciences of the United States of America2010 Mar 164967-7220194787
Ion selectivity of alpha-hemolysin with beta-cyclodextrin adapter. II. Multi-ion effects studied with grand canonical Monte Carlo/Brownian dynamics simulations.Egwolf, Bernhard; Luo, Yun; Walters, D Eric; Roux, BenoitThe journal of physical chemistry. B2010 Mar 42901-920146515
Radiation damage effects at four specimen temperatures from 4 to 100 K.Bammes, Benjamin E; Jakana, Joanita; Schmid, Michael F; Chiu, WahJournal of structural biology2010 Mar331-4119903530
Lateral Mobility of E-cadherin Enhances Rac1 Response in Epithelial Cells.Tsai, J; Kam, L CCellular and molecular bioengineering2010 Mar 184-9020368760
Time-resolved single-step protease activity quantification using nanoplasmonic resonator sensors.Sun, Cheng; Su, Kai-Hung; Valentine, Jason; Rosa-Bauza, Yazmin T; Ellman, Jonathan A; Elboudwarej, Omeed; Mukherjee, Bipasha; Craik, Charles S; Shuman, Marc A; Chen, Fanqing Frank; Zhang, XiangACS nano2010 Feb 23978-8420121209
Bioinspired nanocorals with decoupled cellular targeting and sensing functionality.Wu, Liz Y; Ross, Benjamin M; Hong, SoonGweon; Lee, Luke PSmall (Weinheim an der Bergstrasse, Germany)2010 Feb 22503-720108232
Semiconductor nanocrystals: structure, properties, and band gap engineering.Smith, Andrew M; Nie, ShumingAccounts of chemical research2010 Feb 16190-20019827808
Backbone statistical potential from local sequence-structure interactions in protein loops.Rata, Ionel A; Li, Yaohang; Jakobsson, EricThe journal of physical chemistry. B2010 Feb 111859-6920070091
Journal club. A bioengineer discusses how mechanical forces in tissues may promote malignancy.Vogel, ViolaNature2010 Feb 459120130615
Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications.Li, Shuyi; Nguyen, Lynsa; Xiong, Hairong; Wang, Meiyao; Hu, Tom C-C; She, Jin-Xiong; Serkiz, Steven M; Wicks, George G; Dynan, William SNanomedicine : nanotechnology, biology, and medicine2010 Feb127-3619616128
An unexpected ending: noncanonical 3' end processing mechanisms.Wilusz, Jeremy E; Spector, David LRNA (New York, N.Y.)2010 Feb259-6620007330
Cell mechanics and the cytoskeleton.Fletcher, Daniel A; Mullins, R DycheNature2010 Jan 28485-9220110992
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Phototransistor-based optoelectronic tweezers for dynamic cell manipulation in cell culture media.Hsu, Hsan-yin; Ohta, Aaron T; Chiou, Pei-Yu; Jamshidi, Arash; Neale, Steven L; Wu, Ming CLab on a chip2010 Jan 21165-7220066243
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From artificial atoms to nanocrystal molecules: preparation and properties of more complex nanostructures.Choi, Charina L; Alivisatos, A PaulAnnual review of physical chemistry2010369-8920055683
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Design and application of single fluorophore dual-view imaging system containing both the objective- and prism-type TIRF.Zhang, Hui; Shu, Dan; Wang, Wenjuan; Guo, PeixuanProceedings of SPIE2010757107-75710820436791
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Improving predicted protein loop structure ranking using a Pareto-optimality consensus method.Li, Yaohang; Rata, Ionel; Chiu, See-wing; Jakobsson, EricBMC structural biology20102220642859
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Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey.Heider, Barbara; Nathanson, Jason L; Isacoff, Ehud Y; Callaway, Edward M; Siegel, Ralph MPloS one2010e1382921079806
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Integrin activation dynamics between the RGD-binding site and the headpiece hinge.Puklin-Faucher, Eileen; Vogel, ViolaThe Journal of biological chemistry2009 Dec 2536557-6819762919
Learning rates and states from biophysical time series: a Bayesian approach to model selection and single-molecule FRET data.Bronson, Jonathan E; Fei, Jingyi; Hofman, Jake M; Gonzalez Jr, Ruben L; Wiggins, Chris HBiophysical journal2009 Dec 163196-20520006957
Comprehensive molecular structure of the eukaryotic ribosome.Taylor, Derek J; Devkota, Batsal; Huang, Andrew D; Topf, Maya; Narayanan, Eswar; Sali, Andrej; Harvey, Stephen C; Frank, JoachimStructure (London, England : 1993)2009 Dec 91591-60420004163
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Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous.Dalkara, Deniz; Kolstad, Kathleen D; Caporale, Natalia; Visel, Meike; Klimczak, Ryan R; Schaffer, David V; Flannery, John GMolecular therapy : the journal of the American Society of Gene Therapy2009 Dec2096-10219672248
Exploiting fluorescence resonance energy transfer to probe structural changes in a macromolecule during adsorption and incorporation into a growing biomineral crystal.Touryan, Lara A; Baneyx, Gretchen; Vogel, ViolaColloids and surfaces. B, Biointerfaces2009 Dec 1401-919699065
Stretched extracellular matrix proteins turn fouling and are functionally rescued by the chaperones albumin and casein.Little, William C; Schwartlander, Ruth; Smith, Michael L; Gourdon, Delphine; Vogel, ViolaNano letters2009 Dec4158-6719743815
Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation.Ranzinger, Julia; Krippner-Heidenreich, Anja; Haraszti, Tamas; Bock, Eva; Tepperink, Jessica; Spatz, Joachim P; Scheurich, PeterNano letters2009 Dec4240-519772290
The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.Tam, Stephen; Spiess, Christoph; Auyeung, William; Joachimiak, Lukasz; Chen, Bryan; Poirier, Michelle A; Frydman, JudithNature structural & molecular biology2009 Dec1279-8519915590
Crosslinking of cell-derived 3D scaffolds up-regulates the stretching and unfolding of new extracellular matrix assembled by reseeded cells.Kubow, Kristopher E; Klotzsch, Enrico; Smith, Michael L; Gourdon, Delphine; Little, William C; Vogel, ViolaIntegrative biology : quantitative biosciences from nano to macro2009 Dec635-4820027372
Optoelectronic Tweezers as a Tool for Parallel Single-Cell Manipulation and Stimulation.Valley, Justin K; Ohta, Aaron T; Hsu, Hsan-Yin; Neale, Steven L; Jamshidi, Arash; Wu, Ming CIEEE transactions on biomedical circuits and systems2009 Dec 1424-43120543904
A light-induced dielectrophoretic droplet manipulation platform.Park, Sung-Yong; Kalim, Sheraz; Callahan, Caitlin; Teitell, Michael A; Chiou, Eric P YLab on a chip2009 Nov 213228-3519865729
Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase.Puthenveetil, Sujiet; Liu, Daniel S; White, Katharine A; Thompson, Samuel; Ting, Alice YJournal of the American Chemical Society2009 Nov 1816430-819863063
Phase separation in binary mixtures of bipolar and monopolar lipid dispersions revealed by 2H NMR spectroscopy, small angle x-ray scattering, and molecular theory.Brownholland, David P; Longo, Gabriel S; Struts, Andrey V; Justice, Matthew J; Szleifer, Igal; Petrache, Horia I; Brown, Michael F; Thompson, David HBiophysical journal2009 Nov 182700-919917223
Dependence of macroscopic wetting on nanoscopic surface textures.Wong, Tak-Sing; Ho, Chih-MingLangmuir : the ACS journal of surfaces and colloids2009 Nov 1712851-419842620
Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.Vasiliver-Shamis, Gaia; Cho, Michael W; Hioe, Catarina E; Dustin, Michael LJournal of virology2009 Nov11341-5519710135
Engineering of the fluorescent-energy-conversion arm of phi29 DNA packaging motor for single-molecule studies.Lee, Tae Jin; Zhang, Hui; Chang, Chun-Li; Savran, Cagri; Guo, PeixuanSmall (Weinheim an der Bergstrasse, Germany)2009 Nov2453-919743427
Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanopores.Wendell, David; Jing, Peng; Geng, Jia; Subramaniam, Varuni; Lee, Tae Jin; Montemagno, Carlo; Guo, PeixuanNature nanotechnology2009 Nov765-7219893523
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Gold-Tipped Elastomeric Pillars for Cellular Mechanotransduction.Ghassemi, S; Rossier, O; Sheetz, M P; Wind, S J; Hone, JJournal of vacuum science & technology. B, Microelectronics and nanometer structures : processing, measurement, and phenomena : an official journal of the American Vacuum Society2009 Nov 13088-309120526428
Optical control of zebrafish behavior with halorhodopsin.Arrenberg, Aristides B; Del Bene, Filippo; Baier, HerwigProceedings of the National Academy of Sciences of the United States of America2009 Oct 2017968-7319805086
Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy.Hosseini, Babak H; Louban, Ilia; Djandji, Dominik; Wabnitz, Guido H; Deeg, Janosch; Bulbuc, Nadja; Samstag, Yvonne; Gunzer, Matthias; Spatz, Joachim P; Hammerling, Gunter JProceedings of the National Academy of Sciences of the United States of America2009 Oct 2017852-719822763
An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome.Forster, Friedrich; Lasker, Keren; Beck, Florian; Nickell, Stephan; Sali, Andrej; Baumeister, WolfgangBiochemical and biophysical research communications2009 Oct 16228-3319653995
Spatiotemporal control of cell signalling using a light-switchable protein interaction.Levskaya, Anselm; Weiner, Orion D; Lim, Wendell A; Voigt, Christopher ANature2009 Oct 15997-100119749742
Biologically functional cationic phospholipid-gold nanoplasmonic carriers of RNA.Lee, Somin Eunice; Sasaki, Darryl Y; Perroud, Thomas D; Yoo, Daniel; Patel, Kamlesh D; Lee, Luke PJournal of the American Chemical Society2009 Oct 714066-7419746908
Construction of bacteriophage phi29 DNA packaging motor and its applications in nanotechnology and therapy.Lee, Tae Jin; Schwartz, Chad; Guo, PeixuanAnnals of biomedical engineering2009 Oct2064-8119495981
Gradient lithography of engineered proteins to fabricate 2D and 3D cell culture microenvironments.Wang, Sheng; Wong Po Foo, Cheryl; Warrier, Ajithkumar; Poo, Mu-Ming; Heilshorn, Sarah C; Zhang, XiangBiomedical microdevices2009 Oct1127-3419495986
Capturing the nanoscale complexity of cellular membranes in supported lipid bilayers.Kam, Lance CJournal of structural biology2009 Oct10-Mar19500676
Tat peptide is capable of importing large nanoparticles across nuclear membrane in digitonin permeabilized cells.Nitin, Nitin; LaConte, Leslie; Rhee, Won Jong; Bao, GangAnnals of biomedical engineering2009 Oct2018-2719657743
Strain-dependent photoluminescence behavior of CdSe/CdS nanocrystals with spherical, linear, and branched topologies.Choi, Charina L; Koski, Kristie J; Sivasankar, Sanjeevi; Alivisatos, A PaulNano letters2009 Oct3544-919678687
Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress.Balatoni, Cynthia E; Dawson, David W; Suh, Jane; Sherman, Mara H; Sanders, Grant; Hong, Jason S; Frank, Matthew J; Malone, Cindy S; Said, Jonathan W; Teitell, Michael AThe American journal of pathology2009 Oct1653-6119717643
Robust pattern transfer of nanoimprinted features for sub-5-nm fabrication.Schvartzman, Mark; Wind, Shalom JNano letters2009 Oct3629-3419722536
Genetic and optical targeting of neural circuits and behavior--zebrafish in the spotlight.Baier, Herwig; Scott, Ethan KCurrent opinion in neurobiology2009 Oct553-6019781935
Automated design of synthetic ribosome binding sites to control protein expression.Salis, Howard M; Mirsky, Ethan A; Voigt, Christopher ANature biotechnology2009 Oct946-5019801975
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Spectral solutions to stochastic models of gene expression with bursts and regulation.Mugler, Andrew; Walczak, Aleksandra M; Wiggins, Chris HPhysical review. E, Statistical, nonlinear, and soft matter physics2009 Oct04192119905356
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Self-aligned supported lipid bilayers for patterning the cell-substrate interface.Shen, Keyue; Tsai, Jones; Shi, Peng; Kam, Lance CJournal of the American Chemical Society2009 Sep 2313204-519708648
Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.Roca-Cusachs, Pere; Gauthier, Nils C; Del Rio, Armando; Sheetz, Michael PProceedings of the National Academy of Sciences of the United States of America2009 Sep 2216245-5019805288
Optogenetic dissection of a behavioural module in the vertebrate spinal cord.Wyart, Claire; Del Bene, Filippo; Warp, Erica; Scott, Ethan K; Trauner, Dirk; Baier, Herwig; Isacoff, Ehud YNature2009 Sep 17407-1019759620
Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation.Fei, Jingyi; Bronson, Jonathan E; Hofman, Jake M; Srinivas, Rathi L; Wiggins, Chris H; Gonzalez Jr, Ruben LProceedings of the National Academy of Sciences of the United States of America2009 Sep 1515702-719717422
Silica nanoparticle supported lipid bilayers for gene delivery.Liu, Juewen; Stace-Naughton, Alison; Brinker, C JeffreyChemical communications (Cambridge, England)2009 Sep 145100-220448959
Refinement of protein structures into low-resolution density maps using rosetta.DiMaio, Frank; Tyka, Michael D; Baker, Matthew L; Chiu, Wah; Baker, DavidJournal of molecular biology2009 Sep 11181-9019596339
Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway.Liu, Cambrian Y; Fraser, Scott E; Koos, David SThe Journal of comparative neurology2009 Sep 136-4819565523
Biology under construction: in vitro reconstitution of cellular function.Liu, Allen P; Fletcher, Daniel ANature reviews. Molecular cell biology2009 Sep644-5019672276
Surface molecular property modifications for poly(dimethylsiloxane) (PDMS) based microfluidic devices.Wong, Ieong; Ho, Chih-MingMicrofluidics and nanofluidics2009 Sep 1291-30620357909
Quantifying evolvability in small biological networks.Mugler, A; Ziv, E; Nemenman, I; Wiggins, C HIET systems biology2009 Sep379-8721028928
Adjustable ellipsoid nanoparticles assembled from re-engineered connectors of the bacteriophage phi29 DNA packaging motor.Xiao, Feng; Cai, Ying; Wang, Joseph Che-Yen; Green, Dominik; Cheng, R Holland; Demeler, Borries; Guo, PeixuanACS nano2009 Aug 252163-7019634910
Defining network topologies that can achieve biochemical adaptation.Ma, Wenzhe; Trusina, Ala; El-Samad, Hana; Lim, Wendell A; Tang, ChaoCell2009 Aug 21760-7319703401
Characterization of lipid-templated silica and hybrid thin film mesophases by grazing incidence small-angle X-ray scattering.Dunphy, Darren R; Alam, Todd M; Tate, Michael P; Hillhouse, Hugh W; Smarsly, Bernd; Collord, Andrew D; Carnes, Eric; Baca, Helen K; Kohn, Ralf; Sprung, Michael; Wang, Jin; Brinker, C JeffreyLangmuir : the ACS journal of surfaces and colloids2009 Aug 189500-919496546
E. coli expression of a soluble, active single-chain antibody variable fragment containing a nuclear localization signal.Xiong, Hairong; Li, Shuyi; Yang, Zhanqiu; Burgess, Richard R; Dynan, William SProtein expression and purification2009 Aug172-8019281848
NanoPen: dynamic, low-power, and light-actuated patterning of nanoparticles.Jamshidi, Arash; Neale, Steven L; Yu, Kyoungsik; Pauzauskie, Peter J; Schuck, Peter James; Valley, Justin K; Hsu, Hsan-Yin; Ohta, Aaron T; Wu, Ming CNano letters2009 Aug2921-519588985
Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling.Mandell, Daniel J; Coutsias, Evangelos A; Kortemme, TanjaNature methods2009 Aug551-219644455
In vivo brain imaging using a portable 2.9 g two-photon microscope based on a microelectromechanical systems scanning mirror.Piyawattanametha, Wibool; Cocker, Eric D; Burns, Laurie D; Barretto, Robert P; Jung, Juergen C; Ra, Hyejun; Solgaard, Olav; Schnitzer, Mark JOptics letters2009 Aug 12309-1119649080
Next-generation quantum dots.Smith, Andrew M; Nie, ShumingNature biotechnology2009 Aug732-319668181
Ion Rejection by Nanoporous Membranes in Pressure-Driven Molecular Dynamics Simulations.Leung, Kevin; Rempe, Susan BJournal of computational and theoretical nanoscience2009 Aug 11948-195520221310
Inkjet formation of unilamellar lipid vesicles for cell-like encapsulation.Stachowiak, Jeanne C; Richmond, David L; Li, Thomas H; Brochard-Wyart, Francoise; Fletcher, Daniel ALab on a chip2009 Jul 212003-919568667
Highly Sensitive, Mechanically Stable Nanopore Sensors for DNA Analysis.Venkatesan, Bala Murali; Dorvel, Brian; Yemenicioglu, Sukru; Watkins, Nicholas; Petrov, Ivan; Bashir, RashidAdvanced materials (Deerfield Beach, Fla.)2009 Jul 20277120098720
Kinetic buffering of cross talk between bacterial two-component sensors.Groban, Eli S; Clarke, Elizabeth J; Salis, Howard M; Miller, Susan M; Voigt, Christopher AJournal of molecular biology2009 Jul 17380-9319445950
Cell kinase activity assay based on surface enhanced Raman spectroscopy.Yue, Zhicao; Zhuang, Fengfeng; Kumar, Rajar; Wang, Ieong; Cronin, Stephen B; Liu, Yi-HsinSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2009 Jul 15226-3019299194
Traction on immobilized netrin-1 is sufficient to reorient axons.Moore, Simon W; Biais, Nicolas; Sheetz, Michael PScience (New York, N.Y.)2009 Jul 1016619589994
Pseudomonas aeruginosa Inhibition of Flagellin-activated NF-kappaB and interleukin-8 by human airway epithelial cells.Pena, Jose; Fu, Zhu; Schwarzer, Christian; Machen, Terry EInfection and immunity2009 Jul2857-6519451246
Long noncoding RNAs: functional surprises from the RNA world.Wilusz, Jeremy E; Sunwoo, Hongjae; Spector, David LGenes & development2009 Jul 11494-50419571179
Parallel single-cell light-induced electroporation and dielectrophoretic manipulation.Valley, Justin K; Neale, Steven; Hsu, Hsan-Yin; Ohta, Aaron T; Jamshidi, Arash; Wu, Ming CLab on a chip2009 Jun 211714-2019495455
Cell attachment behavior on solid and fluid substrates exhibiting spatial patterns of physical properties.Oliver, Ann E; Ngassam, Viviane; Dang, Phuong; Sanii, Babak; Wu, Huawen; Yee, Chanel K; Yeh, Yin; Parikh, Atul NLangmuir : the ACS journal of surfaces and colloids2009 Jun 166992-619453187
Electrostatically mediated liposome fusion and lipid exchange with a nanoparticle-supported bilayer for control of surface charge, drug containment, and delivery.Liu, Juewen; Jiang, Xingmao; Ashley, Carlee; Brinker, C JeffreyJournal of the American Chemical Society2009 Jun 107567-919445508
Axon initiation and growth cone turning on bound protein gradients.Mai, Junyu; Fok, Lee; Gao, Hongfeng; Zhang, Xiang; Poo, Mu-MingThe Journal of neuroscience : the official journal of the Society for Neuroscience2009 Jun 107450-819515913
Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility.Babor, Mariana; Kortemme, TanjaProteins2009 Jun846-5819194863
Optimization strategies for electrospun silk fibroin tissue engineering scaffolds.Meinel, Anne J; Kubow, Kristopher E; Klotzsch, Enrico; Garcia-Fuentes, Marcos; Smith, Michael L; Vogel, Viola; Merkle, Hans P; Meinel, LorenzBiomaterials2009 Jun3058-6719233463
Simulation of charge transport in ion channels and nanopores with anisotropic permittivity.Toghraee, Reza; Mashl, R Jay; Lee, Kyu Il; Jakobsson, Eric; Ravaioli, UmbertoJournal of computational electronics2009 Jun 198-10920445807
The predicted structure of the headpiece of the Huntingtin protein and its implications on Huntingtin aggregation.Kelley, Nicholas W; Huang, Xuhui; Tam, Stephen; Spiess, Christoph; Frydman, Judith; Pande, Vijay SJournal of molecular biology2009 May 22919-2719361448
Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy.Cong, Yao; Zhang, Qinfen; Woolford, David; Schweikardt, Thorsten; Khant, Htet; Dougherty, Matthew; Ludtke, Steven J; Chiu, Wah; Decker, HeinzStructure (London, England : 1993)2009 May 13749-5819446530
T cell antigen receptor signaling and immunological synapse stability require myosin IIA.Ilani, Tal; Vasiliver-Shamis, Gaia; Vardhana, Santosh; Bretscher, Anthony; Dustin, Michael LNature immunology2009 May531-919349987
Optical properties of the crescent-shaped nanohole antenna.Wu, Liz Y; Ross, Benjamin M; Lee, Luke PNano letters2009 May1956-6119354226
Inferential optimization for simultaneous fitting of multiple components into a CryoEM map of their assembly.Lasker, Keren; Topf, Maya; Sali, Andrej; Wolfson, Haim JJournal of molecular biology2009 Apr 24180-9419233204
Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR.Numano, Rika; Szobota, Stephanie; Lau, Albert Y; Gorostiza, Pau; Volgraf, Matthew; Roux, Benoit; Trauner, Dirk; Isacoff, Ehud YProceedings of the National Academy of Sciences of the United States of America2009 Apr 216814-919342491
A stochastic spectral analysis of transcriptional regulatory cascades.Walczak, Aleksandra M; Mugler, Andrew; Wiggins, Chris HProceedings of the National Academy of Sciences of the United States of America2009 Apr 216529-3419351901
The cellular context of T cell signaling.Dustin, Michael LImmunity2009 Apr 17482-9219371714
Approaches for stoichiometry and distance determination of nanometer bio-complex by dual-channel single molecule imaging.Zhang, Hui; Shu, Dan; Browne, Mark; Guo, PeixuanIEEE/NIH Life Science Systems and Applications Workshop. IEEE/NIH Life Science Systems and Applications Workshop2009 Apr 9124-12720485472
Plasma fluorination of diamond-like carbon surfaces: mechanism and application to nanoimprint lithography.Schvartzman, M; Wind, S JNanotechnology2009 Apr 814530619420525
Aptamer-based electrochemical biosensor for Botulinum neurotoxin.Wei, Fang; Ho, Chih-MingAnalytical and bioanalytical chemistry2009 Apr1943-819234874
Nuclear neighborhoods and gene expression.Zhao, Rui; Bodnar, Megan S; Spector, David LCurrent opinion in genetics & development2009 Apr172-919339170
Identifying Components in 3D Density Maps of Protein Nanomachines by Multi-scale Segmentation.Pintilie, Grigore; Zhang, Junjie; Chiu, Wah; Gossard, DavidIEEE/NIH Life Science Systems and Applications Workshop. IEEE/NIH Life Science Systems and Applications Workshop2009 Apr 144-4720556220
Trap profiles of projector based optoelectronic tweezers (OET) with HeLa cells.Neale, Steven L; Ohta, Aaron T; Hsu, Hsan-Yin; Valley, Justin K; Jamshidi, Arash; Wu, Ming COptics express2009 Mar 305232-919333286
Structural studies of HIV-1 Gag p6ct and its interaction with Vpr determined by solution nuclear magnetic resonance.Salgado, Gilmar F; Marquant, Rodrigue; Vogel, Alexander; Alves, Isabel D; Feller, Scott E; Morellet, Nelly; Bouaziz, SergeBiochemistry2009 Mar 242355-6719254034
The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation.Good, Matthew; Tang, Grace; Singleton, Julie; Remenyi, Attila; Lim, Wendell ACell2009 Mar 201085-9719303851
Early stages of oxidative stress-induced membrane permeabilization: a neutron reflectometry study.Smith, Hillary L; Howland, Michael C; Szmodis, Alan W; Li, Qijuan; Daemen, Luke L; Parikh, Atul N; Majewski, JaroslawJournal of the American Chemical Society2009 Mar 183631-819275260
Rigidity-dependent cross talk between integrin and cadherin signaling.Tsai, Jones; Kam, LanceBiophysical journal2009 Mar 18L39-4119289031
Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas.Frank, Matthew J; Dawson, David W; Bensinger, Steven J; Hong, Jason S; Knosp, Wendy M; Xu, Lizhong; Balatoni, Cynthia E; Allen, Eric L; Shen, Rhine R; Bar-Sagi, Dafna; Martin, Gail R; Teitell, Michael ABlood2009 Mar 122478-8719147787
An improved united atom force field for simulation of mixed lipid bilayers.Chiu, See-Wing; Pandit, Sagar A; Scott, H L; Jakobsson, EricThe journal of physical chemistry. B2009 Mar 52748-6319708111
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag.Wu, Peng; Shui, Wenqing; Carlson, Brian L; Hu, Nancy; Rabuka, David; Lee, Julia; Bertozzi, Carolyn RProceedings of the National Academy of Sciences of the United States of America2009 Mar 33000-519202059
Impact of order and disorder in RGD nanopatterns on cell adhesion.Huang, Jinghuan; Grater, Stefan V; Corbellini, Francesca; Rinck, Sabine; Bock, Eva; Kemkemer, Ralf; Kessler, Horst; Ding, Jiandong; Spatz, Joachim PNano letters2009 Mar1111-619206508
Creation of functional micro/nano systems through top-down and bottom-up approaches.Wong, Tak-Sing; Brough, Branden; Ho, Chih-MingMolecular & cellular biomechanics : MCB2009 Mar1-5519382535
An Improved United Atom Force Field for Simulation of Mixed Lipid Bilayers.Chiu, See-Wing; Pandit, Sagar A; Scott, H L; Jakobsson, EricThe journal of physical chemistry. B2009 Feb 9NULL19203242
Porous nanoparticle supported lipid bilayers (protocells) as delivery vehicles.Liu, Juewen; Stace-Naughton, Alison; Jiang, Xingmao; Brinker, C JeffreyJournal of the American Chemical Society2009 Feb 41354-519173660
Capture and alignment of phi29 viral particles in sub-40 nanometer porous alumina membranes.Moon, Jeong-Mi; Akin, Demir; Xuan, Yi; Ye, Peide D; Guo, Peixuan; Bashir, RashidBiomedical microdevices2009 Feb135-4218770041
Remote optical switch for localized and selective control of gene interference.Lee, Somin Eunice; Liu, Gang Logan; Kim, Franklin; Lee, Luke PNano letters2009 Feb562-7019128006
Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways.Vogel, Viola; Sheetz, Michael PCurrent opinion in cell biology2009 Feb38-4619217273
The structural dynamics of macromolecular processes.Russel, Daniel; Lasker, Keren; Phillips, Jeremy; Schneidman-Duhovny, Dina; Velazquez-Muriel, Javier A; Sali, AndrejCurrent opinion in cell biology2009 Feb97-10819223165
Protein Mechanics: A New Frontier in Biomechanics.Bao, GExperimental mechanics2009 Feb 1153-16419809588
Titanium-silicon oxide film structures for polarization-modulated infrared reflection absorption spectroscopy.Dunlop, Iain E; Zorn, Stefan; Richter, Gunther; Srot, Vesna; Kelsch, Marion; van Aken, Peter A; Skoda, Maximilian; Gerlach, Alexander; Spatz, Joachim P; Schreiber, FrankThin solid films2009 Jan 302048-205420418963
Fabrication of massive sheets of single layer patterned arrays using lipid directed reengineered phi29 motor dodecamer.Xiao, Feng; Sun, Jinchuan; Coban, Oana; Schoen, Peter; Wang, Joseph Che-Yen; Cheng, R Holland; Guo, PeixuanACS nano2009 Jan 27100-719206255
Cell interactions with hierarchically structured nano-patterned adhesive surfaces.Arnold, Marco; Schwieder, Marco; Blummel, Jacques; Cavalcanti-Adam, Elisabetta A; Lopez-Garcia, Monica; Kessler, Horst; Geiger, Benjamin; Spatz, Joachim PSoft matter2009 Jan 772-7721686049
Multiscale simulations of heterogeneous model membranes.Pandit, Sagar A; Scott, H LarryBiochimica et biophysica acta2009 Jan136-4818848917
JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles.Zhang, Junjie; Nakamura, Natsuko; Shimizu, Yuko; Liang, Nathan; Liu, Xiangan; Jakana, Joanita; Marsh, Michael P; Booth, Christopher R; Shinkawa, Takao; Nakata, Munetaka; Chiu, WahJournal of structural biology2009 Jan1-918926912
JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles.Zhang, Junjie; Nakamura, Natsuko; Shimizu, Yuko; Liang, Nathan; Liu, Xiangan; Jakana, Joanita; Marsh, Michael P; Booth, Christopher R; Shinkawa, Takao; Nakata, Munetaka; Chiu, WahJournal of structural biology2009 Jan9-Jan18926912
Protein segment finder: an online search engine for segment motifs in the PDB.Samson, Abraham O; Levitt, MichaelNucleic acids research2009 JanD224-818974183
Plasmon resonance energy transfer (PRET)-based molecular imaging of cytochrome c in living cells.Choi, Yeonho; Kang, Taewook; Lee, Luke PNano letters2009 Jan85-9019093833
Tuning the optical and electronic properties of colloidal nanocrystals by lattice strain.Smith, Andrew M; Mohs, Aaron M; Nie, ShumingNature nanotechnology2009 Jan56-6319119284
A role for the juxtamembrane cytoplasm in the molecular dynamics of focal adhesions.Wolfenson, Haguy; Lubelski, Ariel; Regev, Tamar; Klafter, Joseph; Henis, Yoav I; Geiger, BenjaminPloS one2009e430419172999
Engineering the Salmonella type III secretion system to export spider silk monomers.Widmaier, Daniel M; Tullman-Ercek, Danielle; Mirsky, Ethan A; Hill, Rena; Govindarajan, Sridhar; Minshull, Jeremy; Voigt, Christopher AMolecular systems biology200930919756048
Fabrication of Nanoscale Bioarrays for the Study of Cytoskeletal Protein Binding Interactions Using Nanoimprint Lithography.Schvartzman, M; Nguyen, K; Palma, M; Abramson, J; Sable, J; Hone, J; Sheetz, M P; Wind, S JJournal of vacuum science & technology. B, Microelectronics and nanometer structures : processing, measurement, and phenomena : an official journal of the American Vacuum Society2009 Jan 161-6519777075
Integrative systems control approach for reactivating Kaposi's sarcoma-associated herpesvirus (KSHV) with combinatory drugs.Sun, Chien-Pin; Usui, Takane; Yu, Fuqu; Al-Shyoukh, Ibrahim; Shamma, Jeff; Sun, Ren; Ho, Chih-MingIntegrative biology : quantitative biosciences from nano to macro2009 Jan123-3019851479
Photochromic blockers of voltage-gated potassium channels.Banghart, Matthew R; Mourot, Alexandre; Fortin, Doris L; Yao, Jennifer Z; Kramer, Richard H; Trauner, DirkAngewandte Chemie (International ed. in English)20099097-10119882609
Mixing solutions in inkjet formed vesicles.Li, Thomas H; Stachowiak, Jeanne C; Fletcher, Daniel AMethods in enzymology200975-9419913162
Cell Separation by Non-Inertial Force Fields in Microfluidic Systems.Tsutsui, Hideaki; Ho, Chih-MingMechanics research communications2009 Jan 192-10320046897
Nanoengineering of Immune Cell Function.Shen, Keyue; Milone, Michael C; Dustin, Michael L; Kam, Lance CMaterials Research Society symposia proceedings. Materials Research Society2009 Jan 1NULL21562611
Reversible switching of pRNA activity on the DNA packaging motor of bacteriophage phi29.Ko, Seung Hyeon; Chen, Yi; Shu, Dan; Guo, Peixuan; Mao, ChengdeJournal of the American Chemical Society2008 Dec 3117684-719049308
Evidence for leaflet-dependent redistribution of charged molecules in fluid supported phospholipid bilayers.Shreve, Andrew P; Howland, Michael C; Sapuri-Butti, Annapoorna R; Allen, Toby W; Parikh, Atul NLangmuir : the ACS journal of surfaces and colloids2008 Dec 213250-319007257
Cooperativity in adhesion cluster formation during initial cell adhesion.Selhuber-Unkel, Christine; Lopez-Garcia, Monica; Kessler, Horst; Spatz, Joachim PBiophysical journal2008 Dec5424-3118689459
Photolithographic patterning of organosilane monolayer for generating large area two-dimensional B lymphocyte arrays.Li, Nan; Ho, Chih-MingLab on a chip2008 Dec2105-1219023473
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.Dimitrova, Nadya; Chen, Yi-Chun M; Spector, David L; de Lange, TitiaNature2008 Nov 27524-818931659
NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells.Nitin, Nitin; Bao, GangBioconjugate chemistry2008 Nov 192205-1118939859
Structural transitions in ion coordination driven by changes in competition for ligand binding.Varma, Sameer; Rempe, Susan BJournal of the American Chemical Society2008 Nov 1915405-1918954053
Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells.Marriott, Gerard; Mao, Shu; Sakata, Tomoyo; Ran, Jing; Jackson, David K; Petchprayoon, Chutima; Gomez, Timothy J; Warp, Erica; Tulyathan, Orapim; Aaron, Holly L; Isacoff, Ehud Y; Yan, YulingProceedings of the National Academy of Sciences of the United States of America2008 Nov 1817789-9419004775
Structure and dynamics of a fluid phase bilayer on a solid support as observed by a molecular dynamics computer simulation.Roark, Matthew; Feller, Scott ELangmuir : the ACS journal of surfaces and colloids2008 Nov 412469-7318850686
Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging.Xiao, Feng; Zhang, Hui; Guo, PeixuanNucleic acids research2008 Nov6620-3218940870
Designing artificial cells to harness the biological ion concentration gradient.Xu, Jian; Lavan, David ANature nanotechnology2008 Nov666-7018989332
Synthesis of a gold nanoparticle dimer plasmonic resonator through two-phase-mediated functionalization.Yim, Tae-Jin; Wang, Yuan; Zhang, XiangNanotechnology2008 Oct 2943560520737026
Protein-nanocrystal conjugates support a single filament polymerization model in R1 plasmid segregation.Choi, Charina L; Claridge, Shelley A; Garner, Ethan C; Alivisatos, A Paul; Mullins, R DycheThe Journal of biological chemistry2008 Oct 1728081-618658133
Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies.Forster, Friedrich; Webb, Benjamin; Krukenberg, Kristin A; Tsuruta, Hiro; Agard, David A; Sali, AndrejJournal of molecular biology2008 Oct 171089-10618694757
Optical switches for remote and noninvasive control of cell signaling.Gorostiza, Pau; Isacoff, Ehud YScience (New York, N.Y.)2008 Oct 17395-918927384
Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor.Lee, Tae Jin; Zhang, Hui; Liang, Dan; Guo, PeixuanVirology2008 Oct 1069-7418701124
Nanoengineering ion channels for optical control.Gorostiza, Pau; Isacoff, Ehud YPhysiology (Bethesda, Md.)2008 Oct238-4718927200
Molecular effects on boundary condition in micronanoliquid flows.Ulmanella, Umberto; Ho, Chih-MingPhysics of fluids (Woodbury, N.Y. : 1994)2008 Oct10151219547719
Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies.Valamehr, Bahram; Jonas, Steven J; Polleux, Julien; Qiao, Rong; Guo, Shuling; Gschweng, Eric H; Stiles, Bangyan; Kam, Korey; Luo, Tzy-Jiun M; Witte, Owen N; Liu, Xin; Dunn, Bruce; Wu, HongProceedings of the National Academy of Sciences of the United States of America2008 Sep 2314459-6418791068
New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo.Rush, Jason S; Bertozzi, Carolyn RJournal of the American Chemical Society2008 Sep 1712240-118722427
A role for confined water in chaperonin function.England, Jeremy L; Lucent, Del; Pande, Vijay SJournal of the American Chemical Society2008 Sep 1011838-918710231
Location and flexibility of the unique C-terminal tail of Aquifex aeolicus co-chaperonin protein 10 as derived by cryo-electron microscopy and biophysical techniques.Chen, Dong-Hua; Luke, Kathryn; Zhang, Junjie; Chiu, Wah; Wittung-Stafshede, PernillaJournal of molecular biology2008 Sep 5707-1718588898
Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches.Hirschfeld-Warneken, Vera C; Arnold, Marco; Cavalcanti-Adam, Ada; Lopez-Garcia, Monica; Kessler, Horst; Spatz, Joachim PEuropean journal of cell biology2008 Sep743-5018572273
Talin depletion reveals independence of initial cell spreading from integrin activation and traction.Zhang, Xian; Jiang, Guoying; Cai, Yunfei; Monkley, Susan J; Critchley, David R; Sheetz, Michael PNature cell biology2008 Sep1062-819160486
Hardware-based anti-Brownian electrokinetic trap (ABEL trap) for single molecules: Control loop simulations and application to ATP binding stoichiometry in multi-subunit enzymes.Jiang, Yan; Wang, Quan; Cohen, Adam E; Douglas, Nick; Frydman, Judith; Moerner, W EProceedings - Society of Photo-Optical Instrumentation Engineers2008 Aug 2912-Jan19823693
The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency.Sallee, Nathan A; Rivera, Gonzalo M; Dueber, John E; Vasilescu, Dan; Mullins, R Dyche; Mayer, Bruce J; Lim, Wendell ANature2008 Aug 211005-818650806
Bioconjugated quantum dots for in vivo molecular and cellular imaging.Smith, Andrew M; Duan, Hongwei; Mohs, Aaron M; Nie, ShumingAdvanced drug delivery reviews2008 Aug 171226-4018495291
Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging.Fang, Yun; Shu, Dan; Xiao, Feng; Guo, Peixuan; Qin, Peter ZBiochemical and biophysical research communications2008 Aug 8589-9418514064
Conformational flexibility facilitates self-assembly of complex DNA nanostructures.Zhang, Chuan; Su, Min; He, Yu; Zhao, Xin; Fang, Ping-an; Ribbe, Alexander E; Jiang, Wen; Mao, ChengdeProceedings of the National Academy of Sciences of the United States of America2008 Aug 510665-918667705
Colloid-guided assembly of oriented 3D neuronal networks.Pautot, Sophie; Wyart, Claire; Isacoff, Ehud YNature methods2008 Aug735-4018641658
Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel.Serysheva, Irina I; Ludtke, Steven J; Baker, Matthew L; Cong, Yao; Topf, Maya; Eramian, David; Sali, Andrej; Hamilton, Susan L; Chiu, WahProceedings of the National Academy of Sciences of the United States of America2008 Jul 159610-518621707
Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing.Arnold, Marco; Hirschfeld-Warneken, Vera C; Lohmuller, Theobald; Heil, Patrick; Blummel, Jacques; Cavalcanti-Adam, Elisabetta A; Lopez-Garcia, Monica; Walther, Paul; Kessler, Horst; Geiger, Benjamin; Spatz, Joachim PNano letters2008 Jul2063-918558788
Limits of filopodium stability.Pronk, Sander; Geissler, Phillip L; Fletcher, Daniel APhysical review letters2008 Jun 2725810218643706
Bayesian approach to network modularity.Hofman, Jake M; Wiggins, Chris HPhysical review letters2008 Jun 2725870118643711
High throughput cell nanomechanics with mechanical imaging interferometry.Reed, Jason; Frank, Matthew; Troke, Joshua J; Schmit, Joanna; Han, Sen; Teitell, Michael A; Gimzewski, James KNanotechnology2008 Jun 1123510120737027
Micropatterning of costimulatory ligands enhances CD4+ T cell function.Shen, Keyue; Thomas, V Kaye; Dustin, Michael L; Kam, Lance CProceedings of the National Academy of Sciences of the United States of America2008 Jun 37791-618505845
End-point targeted molecular dynamics: large-scale conformational changes in potassium channels.Mashl, R J; Jakobsson, EBiophysical journal2008 Jun4307-1918310251
Assay to mechanically tune and optically probe fibrillar fibronectin conformations from fully relaxed to breakage.Little, William C; Smith, Michael L; Ebneter, Urs; Vogel, ViolaMatrix biology : journal of the International Society for Matrix Biology2008 Jun451-6118417335
Cholesterol packing around lipids with saturated and unsaturated chains: a simulation study.Pandit, Sagar A; Chiu, See-Wing; Jakobsson, Eric; Grama, Ananth; Scott, H LLangmuir : the ACS journal of surfaces and colloids2008 Jun 16858-6518517226
Capping protein increases the rate of actin-based motility by promoting filament nucleation by the Arp2/3 complex.Akin, Orkun; Mullins, R DycheCell2008 May 30841-5118510928
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks.Neves, Susana R; Tsokas, Panayiotis; Sarkar, Anamika; Grace, Elizabeth A; Rangamani, Padmini; Taubenfeld, Stephen M; Alberini, Cristina M; Schaff, James C; Blitzer, Robert D; Moraru, Ion I; Iyengar, RaviCell2008 May 16666-8018485874
Controlling Brownian motion of single protein molecules and single fluorophores in aqueous buffer.Cohen, Adam E; Moerner, W EOptics express2008 May 126941-5618545398
Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.Krukenberg, Kristin A; Forster, Friedrich; Rice, Luke M; Sali, Andrej; Agard, David AStructure (London, England : 1993)2008 May755-6518462680
Live cell interferometry reveals cellular dynamism during force propagation.Reed, Jason; Troke, Joshua J; Schmit, Joanna; Han, Sen; Teitell, Michael A; Gimzewski, James KACS nano2008 May841-619206480
Super-resolution imaging by random adsorbed molecule probes.Wu, Dongmin; Liu, Zhaowei; Sun, Cheng; Zhang, XiangNano letters2008 Apr1159-6218321073
Inhibition mechanism of the acetylcholine receptor by alpha-neurotoxins as revealed by normal-mode dynamics.Samson, Abraham O; Levitt, MichaelBiochemistry2008 Apr 14065-7018327915
Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm.Wong, Pak Kin; Yu, Fuqu; Shahangian, Arash; Cheng, Genhong; Sun, Ren; Ho, Chih-MingProceedings of the National Academy of Sciences of the United States of America2008 Apr 15105-1018356295
Crystallization and preliminary X-ray diffraction analysis of recombinant hepatitis E virus-like particle.Wang, Che-Yen; Miyazaki, Naoyuki; Yamashita, Tetsuo; Higashiura, Akifumi; Nakagawa, Atsushi; Li, Tian-Cheng; Takeda, Naokazu; Xing, Li; Hjalmarsson, Erik; Friberg, Claes; Liou, Der-Ming; Sung, Yen-Jen; Tsukihara, Tomitake; Matsuura, Yoshiharu; Miyamura, TActa crystallographica. Section F, Structural biology and crystallization communications2008 Apr 1318-2218391436
Structure of the mammalian 80S ribosome at 8.7 A resolution.Chandramouli, Preethi; Topf, Maya; Menetret, Jean-Francois; Eswar, Narayanan; Cannone, Jamie J; Gutell, Robin R; Sali, Andrej; Akey, Christopher WStructure (London, England : 1993)2008 Apr535-4818400176
Operational Regimes and Physics Present in Optoelectronic Tweezers.Valley, Justin K; Jamshidi, Arash; Ohta, Aaron T; Hsu, Hsan-Yin; Wu, Ming CJournal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems2008 Apr342-35019079767
Chromatin dynamics and gene positioning.Kumaran, R Ileng; Thakar, Rajika; Spector, David LCell2008 Mar 21929-3418358806
Induction and relaxation dynamics of the regulatory network controlling the type III secretion system encoded within Salmonella pathogenicity island 1.Temme, Karsten; Salis, Howard; Tullman-Ercek, Danielle; Levskaya, Anselm; Hong, Soon-Ho; Voigt, Christopher AJournal of molecular biology2008 Mar 1447-6118242639
De novo backbone trace of GroEL from single particle electron cryomicroscopy.Ludtke, Steven J; Baker, Matthew L; Chen, Dong-Hua; Song, Jiu-Li; Chuang, David T; Chiu, WahStructure (London, England : 1993)2008 Mar441-818334219
Aptamer-based optical probes with separated molecular recognition and signal transduction modules.Li, Na; Ho, Chih-MingJournal of the American Chemical Society2008 Feb 272380-118247609
The convergence of bio, nano, and information technology: When Worlds Collide.Ho, Chih-Ming; Chen, Jia MingIEEE nanotechnology magazine2008 Feb 1518-2120953308
K+/Na+ selectivity in K channels and valinomycin: over-coordination versus cavity-size constraints.Varma, Sameer; Sabo, Dubravko; Rempe, Susan BJournal of molecular biology2008 Feb 813-2218155244
Non-Brownian diffusion of membrane molecules in nanopatterned supported lipid bilayers.Tsai, Jones; Sun, Eileen; Gao, Yuan; Hone, James C; Kam, Lance CNano letters2008 Feb425-3018205424
Protein structure fitting and refinement guided by cryo-EM density.Topf, Maya; Lasker, Keren; Webb, Ben; Wolfson, Haim; Chiu, Wah; Sali, AndrejStructure (London, England : 1993)2008 Feb295-30718275820
Understanding and re-engineering nucleoprotein machines to cure human disease.Dynan, William; Takeda, Yoshihiko; Roth, David; Bao, GangNanomedicine (London, England)2008 Feb93-10518393669
Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species.Slavoff, Sarah A; Chen, Irwin; Choi, Yoon-Aa; Ting, Alice YJournal of the American Chemical Society2008 Jan 301160-218171066
Regulating enzymatic activity with a photoswitchable affinity label.Harvey, Jessica H; Trauner, DirkChembiochem : a European journal of chemical biology2008 Jan 25191-318085544
Crystallographic conformers of actin in a biologically active bundle of filaments.Cong, Yao; Topf, Maya; Sali, Andrej; Matsudaira, Paul; Dougherty, Matthew; Chiu, Wah; Schmid, Michael FJournal of molecular biology2008 Jan 11331-618022194
Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading.Dubin-Thaler, Benjamin J; Hofman, Jake M; Cai, Yunfei; Xenias, Harry; Spielman, Ingrid; Shneidman, Anna V; David, Lawrence A; Dobereiner, Hans-Gunther; Wiggins, Chris H; Sheetz, Michael PPloS one2008e373519011687
Fibronectin in aging extracellular matrix fibrils is progressively unfolded by cells and elicits an enhanced rigidity response.Antia, Meher; Baneyx, Gretchen; Kubow, Kristopher E; Vogel, ViolaFaraday discussions2008229-49; discussion 309-25, 419-2019048998
Cell adhesion to agrin presented as a nanopatterned substrate is consistent with an interaction with the extracellular matrix and not transmembrane adhesion molecules.Wolfram, Tobias; Spatz, Joachim P; Burgess, Robert WBMC cell biology20086419055842
Copolymeric nanofilm platform for controlled and localized therapeutic delivery.Chow, Edward Kai-Hua; Pierstorff, Erik; Cheng, Genhong; Ho, DeanACS nano2008 Jan33-4019206545
Dynamic manipulation and separation of individual semiconducting and metallic nanowires.Jamshidi, Arash; Pauzauskie, Peter J; Schuck, P James; Ohta, Aaron T; Chiou, Pei-Yu; Chou, Jeffrey; Yang, Peidong; Wu, Ming CNature photonics200886-8919789729
Human polynucleotide phosphorylase: location matters.Chen, Hsiao-Wen; Koehler, Carla M; Teitell, Michael ATrends in cell biology2007 Dec600-817983748
Modular software platform for low-dose electron microscopy and tomography.Marsh, Michael P; Chang, Juan T; Booth, Christopher R; Liang, Nathan L; Schmid, Michael F; Chiu, WahJournal of microscopy2007 Dec384-918045333
Combining efficient conformational sampling with a deformable elastic network model facilitates structure refinement at low resolution.Schroder, Gunnar F; Brunger, Axel T; Levitt, MichaelStructure (London, England : 1993)2007 Dec1630-4118073112
Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding.Ruan, Gang; Agrawal, Amit; Marcus, Adam I; Nie, ShumingJournal of the American Chemical Society2007 Nov 2814759-6617983227
Protein repellent properties of covalently attached PEG coatings on nanostructured SiO(2)-based interfaces.Blummel, Jacques; Perschmann, Nadine; Aydin, Daniel; Drinjakovic, Jovana; Surrey, Thomas; Lopez-Garcia, Monica; Kessler, Horst; Spatz, Joachim PBiomaterials2007 Nov4739-4717697710
Force-induced unfolding of fibronectin in the extracellular matrix of living cells.Smith, Michael L; Gourdon, Delphine; Little, William C; Kubow, Kristopher E; Eguiluz, R Andresen; Luna-Morris, Sheila; Vogel, ViolaPLoS biology2007 Oct 2e26817914904
Characterization of protein hubs by inferring interacting motifs from protein interactions.Aragues, Ramon; Sali, Andrej; Bonet, Jaume; Marti-Renom, Marc A; Oliva, BaldoPLoS computational biology2007 Sep1761-7117941705
Optically actuated thermocapillary movement of gas bubbles on an absorbing substrate.Ohta, Aaron T; Jamshidi, Arash; Valley, Justin K; Hsu, Hsan-Yin; Wu, Ming CApplied physics letters2007 Aug 14nihpa13082319750203
Functional atlas of the integrin adhesome.Zaidel-Bar, Ronen; Itzkovitz, Shalev; Ma'ayan, Avi; Iyengar, Ravi; Geiger, BenjaminNature cell biology2007 Aug858-6717671451
Design of multi-specificity in protein interfaces.Humphris, Elisabeth L; Kortemme, TanjaPLoS computational biology2007 Auge16417722975
Improved plasmalogen synthesis using organobarium intermediates.Van den Bossche, Jeroen; Shin, Junhwa; Thompson, David HThe Journal of organic chemistry2007 Jun 225005-717539687
Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.Dawson, D W; Hong, J S; Shen, R R; French, S W; Troke, J J; Wu, Y-Z; Chen, S-S; Gui, D; Regelson, M; Marahrens, Y; Morse 3rd, H C; Said, J; Plass, C; Teitell, M AOncogene2007 Jun 214243-5217260020
TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation.Kuraishy, Ali I; French, Samuel W; Sherman, Mara; Herling, Marco; Jones, Dan; Wall, Randolph; Teitell, Michael AProceedings of the National Academy of Sciences of the United States of America2007 Jun 1210175-8017548807
Single molecule transcription profiling with AFM.Reed, Jason; Mishra, Bud; Pittenger, Bede; Magonov, Sergei; Troke, Joshua; Teitell, Michael A; Gimzewski, James KNanotechnology2007 May 94403220721301
Viral nanomotors for packaging of dsDNA and dsRNA.Guo, Peixuan; Lee, Tae JinMolecular microbiology2007 May886-90317501915
Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors.Greenberg, Kenneth P; Geller, Scott F; Schaffer, David V; Flannery, John GInvestigative ophthalmology & visual science2007 Apr1844-5217389520
Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domains.Co, Carl; Wong, Derek T; Gierke, Sarah; Chang, Vicky; Taunton, JackCell2007 Mar 9901-1317350575
The cPLA2 C2alpha domain in solution: structure and dynamics of its Ca2+-activated and cation-free states.Varma, Sameer; Jakobsson, EricBiophysical journal2007 Feb 1966-7617085504
Lateral organization in lipid-cholesterol mixed bilayers.Pandit, Sagar A; Khelashvili, George; Jakobsson, Eric; Grama, Ananth; Scott, H LBiophysical journal2007 Jan 15440-717071661
Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells.Alon, Ronen; Dustin, Michael LImmunity2007 Jan17-2717241958
Environmental signal integration by a modular AND gate.Anderson, J Christopher; Voigt, Christopher A; Arkin, Adam PMolecular systems biology200713317700541
Effects of cytoskeletal disruption on transport, structure, and rheology within mammalian cells.Weihs, Daphne; Mason, Thomas G; Teitell, Michael APhysics of fluids (Woodbury, N.Y. : 1994)200710310219816550
An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate.Chen, Dong-Hua; Song, Jiu-Li; Chuang, David T; Chiu, Wah; Ludtke, Steven JStructure (London, England : 1993)2006 Nov1711-2217098196
Genetic parts to program bacteria.Voigt, Christopher ACurrent opinion in biotechnology2006 Oct548-5716978856
Modifying the function of DNA repair nanomachines for therapeutic benefit.Dynan, William S; Takeda, Yoshihiko; Li, ShuyiNanomedicine : nanotechnology, biology, and medicine2006 Jun74-8117292118
Refinement of protein structures by iterative comparative modeling and CryoEM density fitting.Topf, Maya; Baker, Matthew L; Marti-Renom, Marc A; Chiu, Wah; Sali, AndrejJournal of molecular biology2006 Apr 141655-6816490207
Structural biology of cellular machines.Chiu, Wah; Baker, Matthew L; Almo, Steven CTrends in cell biology2006 Mar144-5016459078


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