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The search results on this publication page are automated on a monthly schedule based on acknowledgment of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.
Knockout Mouse Phenotyping (389)
| Publication Title | Authors | Journal | Publication Date | Page No | PubMedID |
|---|---|---|---|---|---|
| The role of Limch1 alternative splicing in skeletal muscle function. | Penna, Matthew S; Hu, Rong-Chi; Rodney, George G; Cooper, Thomas A | Life science alliance | 2023 Jun | 36977593 | |
| Essential genes: a cross-species perspective. | Cacheiro, Pilar; Smedley, Damian | Mammalian genome : official journal of the International Mammalian Genome Society | 2023 Mar 10 | 36897351 | |
| Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease. | Jones, Kathryn M; Mangin, Elise N; Reynolds, Corey L; Villanueva, Liliana E; Cruz, Julio Vladimir; Versteeg, Leroy; Keegan, Brian; Kendricks, April; Pollet, Jeroen; Gusovsky, Fabian; Bottazzi, Maria Elena; Hotez, Peter J | Frontiers in cellular and infection microbiology | 2023 | 1106315 | 36844399 |
| Knockout mice are an important tool for human monogenic heart disease studies. | Cacheiro, Pilar; Spielmann, Nadine; Mashhadi, Hamed Haseli; Fuchs, Helmut; Gailus-Durner, Valerie; Smedley, Damian; de Angelis, Martin Hrabĕ | Disease models & mechanisms | 2023 May 01 | 36825469 | |
| Genome-wide screening reveals the genetic basis of mammalian embryonic eye development. | Chee, Justine M; Lanoue, Louise; Clary, Dave; Higgins, Kendall; Bower, Lynette; Flenniken, Ann; Guo, Ruolin; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Chin, H-J Genie; Dickinson, Mary E; Hsu, Chih-Wei; Dobbie, Michael; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Mammano, Fabio; Nutter, Lauryl M J; Parkinson, Helen; Qin, Chuan; Shiroishi, Toshi; Sedlacek, Radislav; Seong, J-K; Xu, Ying; International Mouse Phenotyping Consortium; Brooks, Brian; McKerlie, Colin; Lloyd, K C Kent; Westerberg, Henrik; Moshiri, Ala | BMC biology | 2023 Feb 03 | 22 | 36737727 |
| Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages. | Li-Villarreal, Nanbing; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E; Hsu, Chih-Wei | Mammalian genome : official journal of the International Mammalian Genome Society | 2023 Jan 03 | 36595063 | |
| Dysregulated systemic metabolism in a Down syndrome mouse model. | Sarver, Dylan C; Xu, Cheng; Velez, Leandro M; Aja, Susan; Jaffe, Andrew E; Seldin, Marcus M; Reeves, Roger H; Wong, G William | Molecular metabolism | 2023 Feb | 101666 | 36587842 |
| A novel model of gestational diabetes: Acute high fat high sugar diet results in insulin resistance and beta cell dysfunction during pregnancy in mice. | Mishra, Akansha; Ruano, Simone Hernandez; Saha, Pradip K; Pennington, Kathleen A | PloS one | 2022 | 36520818 | |
| Sex differences in allometry for phenotypic traits in mice indicate that females are not scaled males. | Wilson, Laura A B; Zajitschek, Susanne R K; Lagisz, Malgorzata; Mason, Jeremy; Haselimashhadi, Hamed; Nakagawa, Shinichi | Nature communications | 2022 Dec 12 | 36509767 | |
| Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. | Higgins, Kendall; Moore, Bret A; Berberovic, Zorana; Adissu, Hibret A; Eskandarian, Mohammad; Flenniken, Ann M; Shao, Andy; Imai, Denise M; Clary, Dave; Lanoue, Louise; Newbigging, Susan; Nutter, Lauryl M J; Adams, David J; Bosch, Fatima; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Dobbie, Michael; Flicek, Paul; Gao, Xiang; Galande, Sanjeev; Grobler, Anne; Heaney, Jason D; Herault, Yann; de Angelis, Martin Hrabe; Chin, Hsian-Jean Genie; Mammano, Fabio; Qin, Chuan; Shiroishi, Toshihiko; Sedlacek, Radislav; Seong, J-K; Xu, Ying; IMPC Consortium; Lloyd, K C Kent; McKerlie, Colin; Moshiri, Ala | Scientific reports | 2022 Dec 01 | 36456625 | |
| Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. | Jiang, Danye; Burger, Courtney A; Akhanov, Viktor; Liang, Justine H; Mackin, Robert D; Albrecht, Nicholas E; Andrade, Pilar; Schafer, Dorothy P; Samuel, Melanie A | Immunity | 2022 Dec 13 | 36379210 | |
| The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource. | Sollis, Elliot; Mosaku, Abayomi; Abid, Ala; Buniello, Annalisa; Cerezo, Maria; Gil, Laurent; Groza, Tudor; Güneş, Osman; Hall, Peggy; Hayhurst, James; Ibrahim, Arwa; Ji, Yue; John, Sajo; Lewis, Elizabeth; MacArthur, Jacqueline A L; McMahon, Aoife; Osumi-Sutherland, David; Panoutsopoulou, Kalliope; Pendlington, Zoë; Ramachandran, Santhi; Stefancsik, Ray; Stewart, Jonathan; Whetzel, Patricia; Wilson, Robert; Hindorff, Lucia; Cunningham, Fiona; Lambert, Samuel A; Inouye, Michael; Parkinson, Helen; Harris, Laura W | Nucleic acids research | 2022 Nov 09 | 36350656 | |
| The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease. | Groza, Tudor; Gomez, Federico Lopez; Mashhadi, Hamed Haseli; Muñoz-Fuentes, Violeta; Gunes, Osman; Wilson, Robert; Cacheiro, Pilar; Frost, Anthony; Keskivali-Bond, Piia; Vardal, Bora; McCoy, Aaron; Cheng, Tsz Kwan; Santos, Luis; Wells, Sara; Smedley, Damian; Mallon, Ann-Marie; Parkinson, Helen | Nucleic acids research | 2022 Oct 28 | 36305825 | |
| Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice. | Neugebauer, Kerri A; Okros, Maxwell; Guzior, Douglas V; Feiner, Jeremiah; Chargo, Nicholas J; Rzepka, Madison; Schilmiller, Anthony L; O'Reilly, Sandra; Jones, A Daniel; Watson, Victoria E; Luyendyk, James P; McCabe, Laura R; Quinn, Robert A | Journal of lipid research | 2022 Dec | 36243101 | |
| Mendelian gene identification through mouse embryo viability screening. | Cacheiro, Pilar; Westerberg, Carl Henrik; Mager, Jesse; Dickinson, Mary E; Nutter, Lauryl M J; Muñoz-Fuentes, Violeta; Hsu, Chih-Wei; Van den Veyver, Ignatia B; Flenniken, Ann M; McKerlie, Colin; Murray, Stephen A; Teboul, Lydia; Heaney, Jason D; Lloyd, K C Kent; Lanoue, Louise; Braun, Robert E; White, Jacqueline K; Creighton, Amie K; Laurin, Valerie; Guo, Ruolin; Qu, Dawei; Wells, Sara; Cleak, James; Bunton-Stasyshyn, Rosie; Stewart, Michelle; Harrisson, Jackie; Mason, Jeremy; Haseli Mashhadi, Hamed; Parkinson, Helen; Mallon, Ann-Marie; International Mouse Phenotyping Consortium; Genomics England Research Consortium; Smedley, Damian | Genome medicine | 2022 Oct 13 | 36229886 | |
| Promoting validation and cross-phylogenetic integration in model organism research. | Cheng, Keith C; Burdine, Rebecca D; Dickinson, Mary E; Ekker, Stephen C; Lin, Alex Y; Lloyd, K C Kent; Lutz, Cathleen M; MacRae, Calum A; Morrison, John H; O'Connor, David H; Postlethwait, John H; Rogers, Crystal D; Sanchez, Susan; Simpson, Julie H; Talbot, William S; Wallace, Douglas C; Weimer, Jill M; Bellen, Hugo J | Disease models & mechanisms | 2022 09 01 | 36125045 | |
| Clinical exome sequencing uncovers a high frequency of Mendelian disorders in infants with stroke: A retrospective analysis. | Kumar, Runjun D; Meng, Linyan; Liu, Pengfei; Miyake, Christina Y; Worley, Kim C; Bi, Weimin; Lalani, Seema R | American journal of medical genetics. Part A | 2022 Sep 06 | 36065636 | |
| Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. | Liang, Justine H; Alevy, Jonathan; Akhanov, Viktor; Seo, Ryan; Massey, Cory A; Jiang, Danye; Zhou, Joy; Sillitoe, Roy V; Noebels, Jeffrey L; Samuel, Melanie A | Disease models & mechanisms | 2022 09 01 | 35972048 | |
| Multivariate phenotype analysis enables genome-wide inference of mammalian gene function. | Nicholson, George; Morgan, Hugh; Ganjgahi, Habib; Brown, Steve D M; Mallon, Ann-Marie; Holmes, Chris | PLoS biology | 2022 Aug | 35944064 | |
| Phenotype-aware prioritisation of rare Mendelian disease variants. | Kelly, Catherine; Szabo, Anita; Pontikos, Nikolas; Arno, Gavin; Robinson, Peter N; Jacobsen, Jules O B; Smedley, Damian; Cipriani, Valentina | Trends in genetics : TIG | 2022 Dec | 1271-1283 | 35934592 |
| Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer. | Pulliam, Thomas L; Awad, Dominik; Han, Jenny J; Murray, Mollianne M; Ackroyd, Jeffrey J; Goli, Pavithr; Oakhill, Jonathan S; Scott, John W; Ittmann, Michael M; Frigo, Daniel E | Cells | 2022 06 10 | 35741020 | |
| Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation. | Chattopadhyay, Abhijnan; Guan, Pujun; Majumder, Suravi; Kaw, Kaveeta; Zhou, Zhen; Zhang, Chen; Prakash, Siddharth K; Kaw, Anita; Buja, L Maximillian; Kwartler, Callie S; Milewicz, Dianna M | Arteriosclerosis, thrombosis, and vascular biology | 2022 08 | 35708026 | |
| The GA4GH Phenopacket schema defines a computable representation of clinical data. | Jacobsen, Julius O B; Baudis, Michael; Baynam, Gareth S; Beckmann, Jacques S; Beltran, Sergi; Buske, Orion J; Callahan, Tiffany J; Chute, Christopher G; Courtot, Mélanie; Danis, Daniel; Elemento, Olivier; Essenwanger, Andrea; Freimuth, Robert R; Gargano, Michael A; Groza, Tudor; Hamosh, Ada; Harris, Nomi L; Kaliyaperumal, Rajaram; Lloyd, Kevin C Kent; Khalifa, Aly; Krawitz, Peter M; Köhler, Sebastian; Laraway, Brian J; Lehväslaiho, Heikki; Matalonga, Leslie; McMurry, Julie A; Metke-Jimenez, Alejandro; Mungall, Christopher J; Munoz-Torres, Monica C; Ogishima, Soichi; Papakonstantinou, Anastasios; Piscia, Davide; Pontikos, Nikolas; Queralt-Rosinach, Núria; Roos, Marco; Sass, Julian; Schofield, Paul N; Seelow, Dominik; Siapos, Anastasios; Smedley, Damian; Smith, Lindsay D; Steinhaus, Robin; Sundaramurthi, Jagadish Chandrabose; Swietlik, Emilia M; Thun, Sylvia; Vasilevsky, Nicole A; Wagner, Alex H; Warner, Jeremy L; Weiland, Claus; GAGH Phenopacket Modeling Consortium; Haendel, Melissa A; Robinson, Peter N | Nature biotechnology | 2022 Jun | 35705716 | |
| Evaluation of phenotype-driven gene prioritization methods for Mendelian diseases. | Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Robinson, Peter N; Smedley, Damian | Briefings in bioinformatics | 2022 09 20 | 35595299 | |
| Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. | Stork, Brittany A; Dean, Adam; Ortiz, Andrea R; Saha, Pradip; Putluri, Nagireddy; Planas-Silva, Maricarmen D; Mahmud, Iqbal; Rajapakshe, Kimal; Coarfa, Cristian; Knapp, Stefan; Lorenzi, Philip L; Kemp, Bruce E; Turk, Benjamin E; Scott, John W; Means, Anthony R; York, Brian | Molecular metabolism | 2022 08 | 35562082 | |
| Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. | Wotton, Janine M; Peterson, Emma; Flenniken, Ann M; Bains, Rasneer S; Veeraragavan, Surabi; Bower, Lynette R; Bubier, Jason A; Parisien, Marc; Bezginov, Alexandr; Haselimashhadi, Hamed; Mason, Jeremy; Moore, Michayla A; Stewart, Michelle E; Clary, Dave A; Delbarre, Daniel J; Anderson, Laura C; D'Souza, Abigail; Goodwin, Leslie O; Harrison, Mark E; Huang, Ziyue; Mckay, Matthew; Qu, Dawei; Santos, Luis; Srinivasan, Subhiksha; Urban, Rachel; Vukobradovic, Igor; Ward, Christopher S; Willett, Amelia M; Braun, Robert E; Brown, Steve D M; Dickinson, Mary E; Heaney, Jason D; Kumar, Vivek; Lloyd, K C Kent; Mallon, Ann-Marie; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Parkinson, Helen; Seavitt, John R; Wells, Sara; Samaco, Rodney C; Chesler, Elissa J; Smedley, Damian; Diatchenko, Luda; Baumbauer, Kyle M; Young, Erin E; Bonin, Robert P; Mandillo, Silvia; White, Jacqueline K; International Mouse Phenotyping Consortium | Pain | 2022 Jun 01 | 35552317 | |
| Mouse mutagenesis and phenotyping to generate models of development and disease. | Gridley, Thomas; Murray, Stephen A | Current topics in developmental biology | 2022 | 35461561 | |
| Phenotype-driven approaches to enhance variant prioritization and diagnosis of rare disease. | Jacobsen, Julius O B; Kelly, Catherine; Cipriani, Valentina; Research Consortium, Genomics England; Mungall, Christopher J; Reese, Justin; Danis, Daniel; Robinson, Peter N; Smedley, Damian | Human mutation | 2022 Apr 07 | 35391505 | |
| Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. | Meng, Huan; Gonzales, Naomi M; Jung, Sung Yun; Lu, Yue; Putluri, Nagireddy; Zhu, Bokai; Dacso, Clifford C; Lonard, David M; O'Malley, Bert W | Cell reports | 2022 03 08 | 35263593 | |
| ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1. | Chukrallah, Lauren G; Badrinath, Aditi; Vittor, Gabrielle G; Snyder, Elizabeth M | Journal of cell science | 2022 02 15 | 35191498 | |
| LMOD2-related dilated cardiomyopathy presenting in late infancy. | Lay, Erica; Azamian, Mahshid S; Denfield, Susan W; Dreyer, William; Spinner, Joseph A; Kearney, Debra; Zhang, Lilei; Worley, Kim C; Bi, Weimin; Lalani, Seema R | American journal of medical genetics. Part A | 2022 Feb 21 | 35188328 | |
| Making sense of the linear genome, gene function and TADs. | Long, Helen S; Greenaway, Simon; Powell, George; Mallon, Ann-Marie; Lindgren, Cecilia M; Simon, Michelle M | Epigenetics & chromatin | 2022 01 29 | 35090532 | |
| Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox. | Song, Shiyang; Tien, Chih-Liang; Cui, Hao; Basil, Paul; Zhu, Ningxia; Gong, Yingyun; Li, Wenbo; Li, Hui; Fan, Qiying; Min Choi, Jong; Luo, Weijia; Xue, Yanfeng; Cao, Rui; Zhou, Wenjun; Ortiz, Andrea R; Stork, Brittany; Mundra, Vatsala; Putluri, Nagireddy; York, Brian; Chu, Maoping; Chang, Jiang; Yun Jung, Sung; Xie, Liang; Song, Jiangping; Zhang, Lilei; Sun, Zheng | Circulation | 2022 02 08 | 35034472 | |
| Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice. | Wu, Yifan; Li, Evan; Knight, Morgan; Adeniyi-Ipadeola, Grace; Song, Li-Zhen; Burns, Alan R; Gazzinelli-Guimaraes, Ana Clara; Fujiwara, Ricardo; Bottazzi, Maria Elena; Weatherhead, Jill E | PLoS neglected tropical diseases | 2021 12 | 34914687 | |
| Dimensional reduction of phenotypes from 53 000 mouse models reveals a diverse landscape of gene function. | Konopka, Tomasz; Vestito, Letizia; Smedley, Damian | Bioinformatics advances | 2021 | vbab026 | 34870209 |
| 100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report. | 100,000 Genomes Project Pilot Investigators; Smedley, Damian; Smith, Katherine R; Martin, Antonio; Thomas, Ellen A; McDonagh, Ellen M; Cipriani, Valentina; Ellingford, Jamie M; Arno, Gavin; Tucci, Arianna; Vandrovcova, Jana; Chan, Georgia; Williams, Hywel J; Ratnaike, Thiloka; Wei, Wei; Stirrups, Kathleen; Ibanez, Kristina; Moutsianas, Loukas; Wielscher, Matthias; Need, Anna; Barnes, Michael R; Vestito, Letizia; Buchanan, James; Wordsworth, Sarah; Ashford, Sofie; Rehmström, Karola; Li, Emily; Fuller, Gavin; Twiss, Philip; Spasic-Boskovic, Olivera; Halsall, Sally; Floto, R Andres; Poole, Kenneth; Wagner, Annette; Mehta, Sarju G; Gurnell, Mark; Burrows, Nigel; James, Roger; Penkett, Christopher; Dewhurst, Eleanor; Gräf, Stefan; Mapeta, Rutendo; Kasanicki, Mary; Haworth, Andrea; Savage, Helen; Babcock, Melanie; Reese, Martin G; Bale, Mark; Baple, Emma; Boustred, Christopher; Brittain, Helen; de Burca, Anna; Bleda, Marta; Devereau, Andrew; Halai, Dina; Haraldsdottir, Eik; Hyder, Zerin; Kasperaviciute, Dalia; Patch, Christine; Polychronopoulos, Dimitris; Matchan, Angela; Sultana, Razvan; Ryten, Mina; Tavares, Ana L T; Tregidgo, Carolyn; Turnbull, Clare; Welland, Matthew; Wood, Suzanne; Snow, Catherine; Williams, Eleanor; Leigh, Sarah; Foulger, Rebecca E; Daugherty, Louise C; Niblock, Olivia; Leong, Ivone U S; Wright, Caroline F; Davies, Jim; Crichton, Charles; Welch, James; Woods, Kerrie; Abulhoul, Lara; Aurora, Paul; Bockenhauer, Detlef; Broomfield, Alexander; Cleary, Maureen A; Lam, Tanya; Dattani, Mehul; Footitt, Emma; Ganesan, Vijeya; Grunewald, Stephanie; Compeyrot-Lacassagne, Sandrine; Muntoni, Francesco; Pilkington, Clarissa; Quinlivan, Rosaline; Thapar, Nikhil; Wallis, Colin; Wedderburn, Lucy R; Worth, Austen; Bueser, Teofila; Compton, Cecilia; Deshpande, Charu; Fassihi, Hiva; Haque, Eshika; Izatt, Louise; Josifova, Dragana; Mohammed, Shehla; Robert, Leema; Rose, Sarah; Ruddy, Deborah; Sarkany, Robert; Say, Genevieve; Shaw, Adam C; Wolejko, Agata; Habib, Bishoy; Burns, Gavin; Hunter, Sarah; Grocock, Russell J; Humphray, Sean J; Robinson, Peter N; Haendel, Melissa; Simpson, Michael A; Banka, Siddharth; Clayton-Smith, Jill; Douzgou, Sofia; Hall, Georgina; Thomas, Huw B; O'Keefe, Raymond T; Michaelides, Michel; Moore, Anthony T; Malka, Sam; Pontikos, Nikolas; Browning, Andrew C; Straub, Volker; Gorman, Gráinne S; Horvath, Rita; Quinton, Richard; Schaefer, Andrew M; Yu-Wai-Man, Patrick; Turnbull, Doug M; McFarland, Robert; Taylor, Robert W; O'Connor, Emer; Yip, Janice; Newland, Katrina; Morris, Huw R; Polke, James; Wood, Nicholas W; Campbell, Carolyn; Camps, Carme; Gibson, Kate; Koelling, Nils; Lester, Tracy; Németh, Andrea H; Palles, Claire; Patel, Smita; Roy, Noemi B A; Sen, Arjune; Taylor, John; Cacheiro, Pilar; Jacobsen, Julius O; Seaby, Eleanor G; Davison, Val; Chitty, Lyn; Douglas, Angela; Naresh, Kikkeri; McMullan, Dom; Ellard, Sian; Temple, I Karen; Mumford, Andrew D; Wilson, Gill; Beales, Phil; Bitner-Glindzicz, Maria; Black, Graeme; Bradley, John R; Brennan, Paul; Burn, John; Chinnery, Patrick F; Elliott, Perry; Flinter, Frances; Houlden, Henry; Irving, Melita; Newman, William; Rahman, Shamima; Sayer, John A; Taylor, Jenny C; Webster, Andrew R; Wilkie, Andrew O M; Ouwehand, Willem H; Raymond, F Lucy; Chisholm, John; Hill, Sue; Bentley, David; Scott, Richard H; Fowler, Tom; Rendon, Augusto; Caulfield, Mark | The New England journal of medicine | 2021 11 11 | 34758253 | |
| Progress towards completing the mutant mouse null resource. | Peterson, Kevin A; Murray, Stephen A | Mammalian genome : official journal of the International Mammalian Genome Society | 2021 Oct 26 | 34698892 | |
| A metabolome atlas of the aging mouse brain. | Ding, Jun; Ji, Jian; Rabow, Zachary; Shen, Tong; Folz, Jacob; Brydges, Christopher R; Fan, Sili; Lu, Xinchen; Mehta, Sajjan; Showalter, Megan R; Zhang, Ying; Araiza, Renee; Bower, Lynette R; Lloyd, K C Kent; Fiehn, Oliver | Nature communications | 2021 10 15 | 34654818 | |
| PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes. | Angelini, Aude; Saha, Pradip K; Jain, Antrix; Jung, Sung Yun; Mynatt, Randall L; Pi, Xinchun; Xie, Liang | Cell reports | 2021 10 05 | 34610308 | |
| Biology before the SOS Response-DNA Damage Mechanisms at Chromosome Fragile Sites. | Fitzgerald, Devon M; Rosenberg, Susan M | Cells | 2021 09 01 | 34571923 | |
| Importing genetically altered animals: ensuring quality. | Birling, M-C; Fray, M D; Kasparek, P; Kopkanova, J; Massimi, M; Matteoni, R; Montoliu, L; Nutter, L M J; Raspa, M; Rozman, J; Ryder, E J; Scavizzi, F; Voikar, V; Wells, S; Pavlovic, G; Teboul, L | Mammalian genome : official journal of the International Mammalian Genome Society | 2022 Mar | 34536110 | |
| Pleiotropy data resource as a primer for investigating co-morbidities/multi-morbidities and their role in disease. | Muñoz-Fuentes, Violeta; Haselimashhadi, Hamed; Santos, Luis; Westerberg, Henrik; Parkinson, Helen; Mason, Jeremy | Mammalian genome : official journal of the International Mammalian Genome Society | 2021 Sep 15 | 34524473 | |
| Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. | Hoffman, Kristyn A; Villar, Maria Jose; Poveda, Cristina; Bottazzi, Maria Elena; Hotez, Peter J; Tweardy, David J; Jones, Kathryn M | Frontiers in cellular and infection microbiology | 2021 | 34504808 | |
| Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. | Mao, Hua; Li, Luge; Fan, Qiying; Angelini, Aude; Saha, Pradip K; Coarfa, Cristian; Rajapakshe, Kimal; Perera, Dimuthu; Cheng, Jizhong; Wu, Huaizhu; Ballantyne, Christie M; Sun, Zheng; Xie, Liang; Pi, Xinchun | Nature communications | 2021 09 06 | 34489478 | |
| Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes. | Lana-Elola, Eva; Cater, Heather; Watson-Scales, Sheona; Greenaway, Simon; Müller-Winkler, Jennifer; Gibbins, Dorota; Nemes, Mihaela; Slender, Amy; Hough, Tertius; Keskivali-Bond, Piia; Scudamore, Cheryl L; Herbert, Eleanor; Banks, Gareth T; Mobbs, Helene; Canonica, Tara; Tosh, Justin; Noy, Suzanna; Llorian, Miriam; Nolan, Patrick M; Griffin, Julian L; Good, Mark; Simon, Michelle; Mallon, Ann-Marie; Wells, Sara; Fisher, Elizabeth M C; Tybulewicz, Victor L J | Disease models & mechanisms | 2021 Oct 01 | 34477842 | |
| COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. | Marom, Ronit; Burrage, Lindsay C; Venditti, Rossella; Clément, Aurélie; Blanco-Sánchez, Bernardo; Jain, Mahim; Scott, Daryl A; Rosenfeld, Jill A; Sutton, V Reid; Shinawi, Marwan; Mirzaa, Ghayda; DeVile, Catherine; Roberts, Rowenna; Calder, Alistair D; Allgrove, Jeremy; Grafe, Ingo; Lanza, Denise G; Li, Xiaohui; Joeng, Kyu Sang; Lee, Yi-Chien; Song, I-Wen; Sliepka, Joseph M; Batkovskyte, Dominyka; Washington, Megan; Dawson, Brian C; Jin, Zixue; Jiang, Ming-Ming; Chen, Shan; Chen, Yuqing; Tran, Alyssa A; Emrick, Lisa T; Murdock, David R; Hanchard, Neil A; Zapata, Gladys E; Mehta, Nitesh R; Weis, Mary Ann; Scott, Abbey A; Tremp, Brenna A; Phillips, Jennifer B; Wegner, Jeremy; Taylor-Miller, Tashunka; Gibbs, Richard A; Muzny, Donna M; Jhangiani, Shalini N; Hicks, John; Stottmann, Rolf W; Dickinson, Mary E; Seavitt, John R; Heaney, Jason D; Eyre, David R; Undiagnosed Diseases Network; Westerfield, Monte; De Matteis, Maria Antonietta; Lee, Brendan | American journal of human genetics | 2021 09 02 | 34450031 | |
| Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor. | Huang, Yung-Hsin; Chen, Chun-Wei; Sundaramurthy, Venkatasubramaniam; Slabicki, Mikolaj; Hao, Dapeng; Watson, Caroline J; Tovy, Ayala; Reyes, Jaime M; Dakhova, Olga; Crovetti, Brielle R; Galonska, Christina; Lee, Minjung; Brunetti, Lorenzo; Zhou, Yubin; Tatton-Brown, Katrina; Huang, Yun; Cheng, Xiaodong; Meissner, Alexander; Valk, Peter J M; Van Maldergem, Lionel; Sanders, Mathijs A; Blundell, Jamie R; Li, Wei; Ebert, Benjamin L; Goodell, Margaret A | Cancer discovery | 2021 Aug 24 | 34429321 | |
| Diffusion enables integration of heterogeneous data and user-driven learning in a desktop knowledge-base. | Konopka, Tomasz; Ng, Sandra; Smedley, Damian | PLoS computational biology | 2021 Aug | 34379637 | |
| TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain. | Kasembeli, Moses M; Singhmar, Pooja; Ma, Jiacheng; Edralin, Jules; Tang, Yongfu; Adams 3rd, Clydell; Heijnen, Cobi J; Kavelaars, Annemieke; Tweardy, David J | Biochemical pharmacology | 2021 Oct | 34274354 | |
| Screening and validation of genome-edited animals. | Bunton-Stasyshyn, Rosie K; Codner, Gemma F; Teboul, Lydia | Laboratory animals | 2022 Feb | 34192966 | |
| A rare description of pure partial trisomy of 16q12.2q24.3 and review of the literature. | Manor, Joshua; Dinu, Daniela; Azamian, Mahshid S; Bi, Weimin; Darilek, Sandra; Lalani, Seema R | American journal of medical genetics. Part A | 2021 Jun 01 | 34061437 | |
| Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. | Mohammed, Yassene; Michaud, Sarah A; Pětrošová, Helena; Yang, Juncong; Ganguly, Milan; Schibli, David; Flenniken, Ann M; Nutter, Lauryl M J; Adissu, Hibret A; Lloyd, K C Kent; McKerlie, Colin; Borchers, Christoph H | NPJ systems biology and applications | 2021 May 28 | 34050187 | |
| REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology. | Sarkans, Ugis; Chiu, Wah; Collinson, Lucy; Darrow, Michele C; Ellenberg, Jan; Grunwald, David; Hériché, Jean-Karim; Iudin, Andrii; Martins, Gabriel G; Meehan, Terry; Narayan, Kedar; Patwardhan, Ardan; Russell, Matthew Robert Geoffrey; Saibil, Helen R; Str | Nature methods | 2021 May 21 | 34021280 | |
| Rap1 in the VMH regulates glucose homeostasis. | Kaneko, Kentaro; Lin, Hsiao-Yun; Fu, Yukiko; Saha, Pradip K; De la Puente-Gomez, Ana B; Xu, Yong; Ohinata, Kousaku; Chen, Peter; Morozov, Alexei; Fukuda, Makoto | JCI insight | 2021 Jun 08 | 33974562 | |
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| Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. | Hoffman, Kristyn; Liu, Zongyuan; Hossain, Ekram; Bottazzi, Maria Elena; Hotez, Peter J; Jones, Kathryn M; McCall, Laura-Isobel | ACS infectious diseases | 2021 06 11 | 33843195 | |
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| REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. | Ding, Guolian; Li, Xin; Hou, Xinguo; Zhou, Wenjun; Gong, Yingyun; Liu, Fuqiang; He, Yanlin; Song, Jia; Wang, Jing; Basil, Paul; Li, Wenbo; Qian, Sichong; Saha, Pradip; Wang, Jinbang; Cui, Chen; Yang, Tingting; Zou, Kexin; Han, Younghun; Amos, Christopher I; Xu, Yong; Chen, Li; Sun, Zheng | Nature | 2021 Apr | 33762728 | |
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| Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling. | Brown, Heather Mary; Murray, Stephen A; Northrup, Hope; Au, Kit Sing; Niswander, Lee A | Development (Cambridge, England) | 2020 11 19 | 33214242 | |
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| Antioxidant Carbon Nanoparticles Inhibit Fibroblast-Like Synoviocyte Invasiveness and Reduce Disease Severity in a Rat Model of Rheumatoid Arthritis. | Tanner, Mark R; Huq, Redwan; Sikkema, William K A; Nilewski, Lizanne G; Yosef, Nejla; Schmitt, Cody; Flores-Suarez, Carlos P; Raugh, Arielle; Laragione, Teresina; Gulko, Pércio S; Tour, James M; Beeton, Christine | Antioxidants (Basel, Switzerland) | 2020 Oct 16 | 33081234 | |
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| Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data. | Sabik, Olivia L; Calabrese, Gina M; Taleghani, Eric; Ackert-Bicknell, Cheryl L; Farber, Charles R | Cell reports | 2020 09 15 | 32937138 | |
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| ADAD1 and ADAD2, testis-specific adenosine deaminase domain-containing proteins, are required for male fertility. | Snyder, Elizabeth; Chukrallah, Lauren; Seltzer, Kelly; Goodwin, Leslie; Braun, Robert E | Scientific reports. | 2020 Jul 14; | 32665638 | |
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| Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice. | Menon, Renuka T; Shrestha, Amrit Kumar; Barrios, Roberto; Reynolds, Corey; Shivanna, Binoy | International journal of molecular sciences. | 2020 Mar 31; | 32244398 | |
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| Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development. | Ngan, Chew Yee; Wong, Chee Hong; Tjong, Harianto; Wang, Wenbo; Goldfeder, Rachel L; Choi, Cindy; He, Hao; Gong, Liang; Lin, Junyan; Urban, Barbara; Chow, Julianna; Li, Meihong; Lim, Joanne; Philip, Vivek; Murray, Stephen A; Wang, Haoyi; Wei, Chia-Lin | Nature genetics. | 2020 03; | 32094912 | |
| Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice. | Menon, Renuka T; Shrestha, Amrit Kumar; Reynolds, Corey L; Barrios, Roberto; Caron, Kathleen M; Shivanna, Binoy | The American journal of pathology. | 2020 03; | 32093901 | |
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| PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. | Yu, Kwanha; Lin, Chia-Ching John; Hatcher, Asante; Lozzi, Brittney; Kong, Kathleen; Huang-Hobbs, Emmet; Cheng, Yi-Ting; Beechar, Vivek B; Zhu, Wenyi; Zhang, Yiqun; Chen, Fengju; Mills, Gordon B; Mohila, Carrie A; Creighton, Chad J; Noebels, Jeffrey L; Scott, Kenneth L; Deneen, Benjamin | Nature. | 2020 02; | 31996845 | |
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| Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. | Findlay, Amy S; McKie, Lisa; Keighren, Margaret; Clementson-Mobbs, Sharon; Sanchez-Pulido, Luis; Wells, Sara; Cross, Sally H; Jackson, Ian J | Scientific reports. | 2020 Jan 16; | 31949211 | |
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| Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. | Hoffman, Kristyn A; Reynolds, Corey; Bottazzi, Maria Elena; Hotez, Peter; Jones, Kathryn | Journal of the American Heart Association. | 2019 11 19; | 31718442 | |
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| Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation. | Zhang, Min; Hill, Matthew C; Kadow, Zachary A; Suh, Ji Ho; Tucker, Nathan R; Hall, Amelia W; Tran, Tien T; Swinton, Paul S; Leach, John P; Margulies, Kenneth B; Ellinor, Patrick T; Li, Na; Martin, James F | Proceedings of the National Academy of Sciences of the United States of America. | 2019 11 05; | 31636200 | |
| Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice. | Kwon, Young Sam; Tham, Addy; Lopez, Antonio Jacobo; Edwards, Sydney; Woods, Sean; Chen, Jiajia; Wong-Fortunato, Jenna; Quiroz Alonso, Alejandra; Javier, Seanne; Au, Ingrid; Clarke, Maria; Humpal, Devin; Lloyd, K C Kent; Thomasy, Sara; Murphy, Christopher; Glaser, Thomas M; Moshiri, Ala | Developmental biology. | 2020 Feb 15; | 31634437 | |
| Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. | Jiang, Danye; Burger, Courtney A; Casasent, Anna K; Albrecht, Nicholas E; Li, Fenge; Samuel, Melanie A | The Journal of comparative neurology. | 2020 Apr 01; | 31609468 | |
| Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data. | Haselimashhadi, Hamed; Mason, Jeremy C; Munoz-Fuentes, Violeta; López-Gómez, Federico; Babalola, Kolawole; Acar, Elif F; Kumar, Vivek; White, Jacqui; Flenniken, Ann M; King, Ruairidh; Straiton, Ewan; Seavitt, John Richard; Gaspero, Angelina; Garza, Arturo; Christianson, Audrey E; Hsu, Chih-Wei; Reynolds, Corey L; Lanza, Denise G; Lorenzo, Isabel; Green, Jennie R; Gallegos, Juan J; Bohat, Ritu; Samaco, Rodney C; Veeraragavan, Surabi; Kim, Jong Kyoung; Miller, Gregor; Fuchs, Helmult; Garrett, Lillian; Becker, Lore; Kang, Yeon Kyung; Clary, David; Cho, Soo Young; Tamura, Masaru; Tanaka, Nobuhiko; Soo, Kyung Dong; Bezginov, Alexandr; About, Ghina Bou; Champy, Marie-France; Vasseur, Laurent; Leblanc, Sophie; Meziane, Hamid; Selloum, Mohammed; Reilly, Patrick T; Spielmann, Nadine; Maier, Holger; Gailus-Durner, Valerie; Sorg, Tania; Hiroshi, Masuya; Yuichi, Obata; Heaney, Jason D; Dickinson, Mary E; Wolfgang, Wurst; Tocchini-Valentini, Glauco P; Lloyd, Kevin C Kent; McKerlie, Colin; Seong, Je Kyung; Yann, Herault; de Angelis, Martin Hrabé; Brown, Steve D M; Smedley, Damian; Flicek, Paul; Mallon, Ann-Marie; Parkinson, Helen; Meehan, Terrence F | Bioinformatics (Oxford, England). | 2019 Oct 08; | 31591642 | |
| Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis. | Xiao, Yang; Hill, Matthew C; Li, Lele; Deshmukh, Vaibhav; Martin, Thomas J; Wang, Jun; Martin, James F | Genes & development. | 2019 11 01; | 31558567 | |
| Genomic Mutation Identification in Mice Using Illumina Sequencing and Linux-Based Computational Methods. | Williams, John A; Powell, George; Mallon, Ann-Marie; Simon, Michelle M | Current protocols in mouse biology | 2019 Sep | 31532925 | |
| Endurance exercise leads to beneficial molecular and physiological effects in a mouse model of myotonic dystrophy type 1. | Sharp, Lydia; Cox, Diana C; Cooper, Thomas A | Muscle & nerve. | 2019 12; | 31509256 | |
| Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation. | Gurumurthy, Channabasavaiah B; O'Brien, Aidan R; Quadros, Rolen M; Adams Jr, John; Alcaide, Pilar; Ayabe, Shinya; Ballard, Johnathan; Batra, Surinder K; Beauchamp, Marie-Claude; Becker, Kathleen A; Bernas, Guillaume; Brough, David; Carrillo-Salinas, Francisco; Chan, Wesley; Chen, Hanying; Dawson, Ruby; DeMambro, Victoria; D'Hont, Jinke; Dibb, Katharine M; Eudy, James D; Gan, Lin; Gao, Jing; Gonzales, Amy; Guntur, Anyonya R; Guo, Huiping; Harms, Donald W; Harrington, Anne; Hentges, Kathryn E; Humphreys, Neil; Imai, Shiho; Ishii, Hideshi; Iwama, Mizuho; Jonasch, Eric; Karolak, Michelle; Keavney, Bernard; Khin, Nay-Chi; Konno, Masamitsu; Kotani, Yuko; Kunihiro, Yayoi; Lakshmanan, Imayavaramban; Larochelle, Catherine; Lawrence, Catherine B; Li, Lin; Lindner, Volkhard; Liu, Xian-De; Lopez-Castejon, Gloria; Loudon, Andrew; Lowe, Jenna; Jerome-Majewska, Loydie A; Matsusaka, Taiji; Miura, Hiromi; Miyasaka, Yoshiki; Morpurgo, Benjamin; Motyl, Katherine; Nabeshima, Yo-Ichi; Nakade, Koji; Nakashiba, Toshiaki; Nakashima, Kenichi; Obata, Yuichi; Ogiwara, Sanae; Ouellet, Mariette; Oxburgh, Leif; Piltz, Sandra; Pinz, Ilka; Ponnusamy, Moorthy P; Ray, David; Redder, Ronald J; Rosen, Clifford J; Ross, Nikki; Ruhe, Mark T; Ryzhova, Larisa; Salvador, Ane M; Alam, Sabrina Shameen; Sedlacek, Radislav; Sharma, Karan; Smith, Chad; Staes, Katrien; Starrs, Lora; Sugiyama, Fumihiro; Takahashi, Satoru; Tanaka, Tomohiro; Trafford, Andrew W; Uno, Yoshihiro; Vanhoutte, Leen; Vanrockeghem, Frederique; Willis, Brandon J; Wright, Christian S; Yamauchi, Yuko; Yi, Xin; Yoshimi, Kazuto; Zhang, Xuesong; Zhang, Yu; Ohtsuka, Masato; Das, Satyabrata; Garry, Daniel J; Hochepied, Tino; Thomas, Paul; Parker-Thornburg, Jan; Adamson, Antony D; Yoshiki, Atsushi; Schmouth, Jean-Francois; Golovko, Andrei; Thompson, William R; Lloyd, K C Kent; Wood, Joshua A; Cowan, Mitra; Mashimo, Tomoji; Mizuno, Seiya; Zhu, Hao; Kasparek, Petr; Liaw, Lucy; Miano, Joseph M; Burgio, Gaetan | Genome biology. | 2019 08 26; | 31446895 | |
| Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. | Moore, Bret A; Flenniken, Ann M; Clary, Dave; Moshiri, Ata S; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammad; McKerlie, Colin; International Mouse Phenotyping Consortium; Thomasy, Sara M; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala | Scientific reports. | 2019 Aug 01; | 31371754 | |
| Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1. | Cyranka, Malgorzata; Veprik, Anna; McKay, Eleanor J; van Loon, Nienke; Thijsse, Amber; Cotter, Luke; Hare, Nisha; Saibudeen, Affan; Lingam, Swathi; Pires, Elisabete; Larraufie, Pierre; Reimann, Frank; Gribble, Fiona; Stewart, Michelle; Bentley, Elizabeth; Lear, Pamela; McCullagh, James; Cantley, James; Cox, Roger D; de Wet, Heidi | Obesity (Silver Spring, Md.). | 2019 Aug; | 31338999 | |
| S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. | Ren, Yi Athena; Monkkonen, Teresa; Lewis, Michael T; Bernard, Daniel J; Christian, Helen C; Jorgez, Carolina J; Moore, Joshua A; Landua, John D; Chin, Haelee M; Chen, Weiqin; Singh, Swarnima; Kim, Ik Sun; Zhang, Xiang Hf; Xia, Yan; Phillips, Kevin J; MacKay, Harry; Waterland, Robert A; Ljungberg, M Cecilia; Saha, Pradip K; Hartig, Sean M; Coll, Tatiana Fiordelisio; Richards, JoAnne S | JCI insight. | 2019 Jul 02; | 31265437 | |
| Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche. | Hu, Tianyuan; Kitano, Ayumi; Luu, Victor; Dawson, Brian; Hoegenauer, Kevin A; Lee, Brendan H; Nakada, Daisuke | Stem cell reports. | 2019 Sep 10; | 31257132 | |
| Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression. | Cordonier, Elizabeth L; Liu, Tiemin; Saito, Kenji; Chen, Siyu S; Xu, Yong; Fukuda, Makoto | Journal of the Endocrine Society. | 2019 Jul 01; | 31214662 | |
| A cellular atlas of Pitx2-dependent cardiac development. | Hill, Matthew C; Kadow, Zachary A; Li, Lele; Tran, Tien T; Wythe, Joshua D; Martin, James F | Development (Cambridge, England). | 2019 Jun 14; | 31201182 | |
| High Resolution Imaging of Mouse Embryos and Neonates with X-Ray Micro-Computed Tomography. | Hsu, Chih-Wei; Kalaga, Sowmya; Akoma, Uchechukwu; Rasmussen, Tara L; Christiansen, Audrey E; Dickinson, Mary E | Current protocols in mouse biology. | 2019 Jun; | 31195428 | |
| Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function. | Alevy, Jonathan; Burger, Courtney A; Albrecht, Nicholas E; Jiang, Danye; Samuel, Melanie A | Neurochemistry international. | 2019 Oct; | 31175897 | |
| Non-monotonic dose-response effects of arsenic on glucose metabolism. | Gong, Yingyun; Liu, Jidong; Xue, Yanfeng; Zhuang, Zhong; Qian, Sichong; Zhou, Wenjun; Li, Xin; Qian, Justin; Ding, Guolian; Sun, Zheng | Toxicology and applied pharmacology. | 2019 Aug 15; | 31170414 | |
| New models for human disease from the International Mouse Phenotyping Consortium. | Cacheiro, Pilar; Haendel, Melissa A; Smedley, Damian; International Mouse Phenotyping Consortium and the Monarch Initiative | Mammalian genome : official journal of the International Mammalian Genome Society. | 2019 Jun; | 31127358 | |
| A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium. | Barupal, Dinesh K; Zhang, Ying; Shen, Tong; Fan, Sili; Roberts, Bryan S; Fitzgerald, Patrick; Wancewicz, Benjamin; Valdiviez, Luis; Wohlgemuth, Gert; Byram, Gregory; Choy, Ying Yng; Haffner, Bennett; Showalter, Megan R; Vaniya, Arpana; Bloszies, Clayton S; Folz, Jacob S; Kind, Tobias; Flenniken, Ann M; McKerlie, Colin; Nutter, Lauryl M J; Lloyd, Kent C; Fiehn, Oliver | Metabolites. | 2019 May 22; | 31121816 | |
| -Omics biomarker identification pipeline for translational medicine. | Bravo-Merodio, Laura; Williams, John A; Gkoutos, Georgios V; Acharjee, Animesh | Journal of translational medicine. | 2019 05 14; | 31088492 | |
| The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming. | Rueda, Elda M; Hall, Benjamin M; Hill, Matthew C; Swinton, Paul G; Tong, Xuefei; Martin, James F; Poché, Ross A | Cell reports. | 2019 May 07; | 31067451 | |
| TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. | Arhatte, Malika; Gunaratne, Gihan S; El Boustany, Charbel; Kuo, Ivana Y; Moro, Céline; Duprat, Fabrice; Plaisant, Magali; Duval, Hélène; Li, Dahui; Picard, Nicolas; Couvreux, Anais; Duranton, Christophe; Rubera, Isabelle; Pagnotta, Sophie; Lacas-Gervais, Sandra; Ehrlich, Barbara E; Marchant, Jonathan S; Savage, Aaron M; van Eeden, Fredericus J M; Wilkinson, Robert N; Demolombe, Sophie; Honoré, Eric; Patel, Amanda | Nature communications. | 2019 05 02; | 31048699 | |
| PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. | Falcão, Ana Mendanha; Meijer, Mandy; Scaglione, Antonella; Rinwa, Puneet; Agirre, Eneritz; Liang, Jialiang; Larsen, Sara C; Heskol, Abeer; Frawley, Rebecca; Klingener, Michael; Varas-Godoy, Manuel; Raposo, Alexandre A S F; Ernfors, Patrik; Castro, Diogo S; Nielsen, Michael L; Casaccia, Patrizia; Castelo-Branco, Gonçalo | Cell reports. | 2019 Apr 23; | 31018126 | |
| Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. | Li, Qiang; Youn, Ji Youn; Siu, Kin Lung; Murugesan, Priya; Zhang, Yixuan; Cai, Hua | Redox biology. | 2019 Jun; | 30954686 | |
| Robust mouse tracking in complex environments using neural networks. | Geuther, Brian Q; Deats, Sean P; Fox, Kai J; Murray, Steve A; Braun, Robert E; White, Jacqueline K; Chesler, Elissa J; Lutz, Cathleen M; Kumar, Vivek | Communications biology. | 2019; | 30937403 | |
| Integrative transcriptomic analysis suggests new autoregulatory splicing events coupled with nonsense-mediated mRNA decay. | Pervouchine, Dmitri; Popov, Yaroslav; Berry, Andy; Borsari, Beatrice; Frankish, Adam; Guigó, Roderic | Nucleic acids research. | 2019 Jun 04; | 30916337 | |
| Depletion of WNT10A Prevents Tumor Growth by Suppressing Microvessels and Collagen Expression. | Kumagai, Motona; Guo, Xin; Wang, Ke-Yong; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Kurose, Nozomu; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi; Yamada, Sohsuke | International journal of medical sciences. | 2019; | 30911276 | |
| Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. | Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Kent Lloyd, K C; Murphy, Christopher J; Moshiri, Ala | Communications biology. | 2019; | 30854487 | |
| Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion. | Jux, Bettina; Gosejacob, Dominic; Tolksdorf, Felix; Mandel, Christa; Rieck, Michael; Namislo, Angrit; Pfeifer, Alexander; Kolanus, Waldemar | Scientific reports. | 2019 Mar 05; | 30837656 | |
| Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1+/-) in mice. | Kim, Soohyun; Thomasy, Sara M; Raghunathan, Vijay Krishna; Teixeira, Leandro B C; Moshiri, Ala; FitzGerald, Paul; Murphy, Christopher J | Molecular vision. | 2019; | 30820148 | |
| Tead1 is required for perinatal cardiomyocyte proliferation. | Liu, Ruya; Jagannathan, Rajaganapathi; Li, Feng; Lee, Jeongkyung; Balasubramanyam, Nikhil; Kim, Byung S; Yang, Ping; Yechoor, Vijay K; Moulik, Mousumi | PloS one. | 2019; | 30811446 | |
| YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. | Monroe, Tanner O; Hill, Matthew C; Morikawa, Yuka; Leach, John P; Heallen, Todd; Cao, Shuyi; Krijger, Peter H L; de Laat, Wouter; Wehrens, Xander H T; Rodney, George G; Martin, James F | Developmental cell. | 2019 Mar 25; | 30773489 | |
| Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. | Burrage, Lindsay C; Reynolds, John J; Baratang, Nissan Vida; Phillips, Jennifer B; Wegner, Jeremy; McFarquhar, Ashley; Higgs, Martin R; Christiansen, Audrey E; Lanza, Denise G; Seavitt, John R; Jain, Mahim; Li, Xiaohui; Parry, David A; Raman, Vandana; Chitayat, David; Chinn, Ivan K; Bertuch, Alison A; Karaviti, Lefkothea; Schlesinger, Alan E; Earl, Dawn; Bamshad, Michael; Savarirayan, Ravi; Doddapaneni, Harsha; Muzny, Donna; Jhangiani, Shalini N; Eng, Christine M; Gibbs, Richard A; Bi, Weimin; Emrick, Lisa; Rosenfeld, Jill A; Postlethwait, John; Westerfield, Monte; Dickinson, Mary E; Beaudet, Arthur L; Ranza, Emmanuelle; Huber, Celine; Cormier-Daire, Valérie; Shen, Wei; Mao, Rong; Heaney, Jason D; Orange, Jordan S; University of Washington Center for Mendelian Genomics; Undiagnosed Diseases Network; Bertola, Débora; Yamamoto, Guilherme L; Baratela, Wagner A R; Butler, Merlin G; Ali, Asim; Adeli, Mehdi; Cohn, Daniel H; Krakow, Deborah; Jackson, Andrew P; Lees, Melissa; Offiah, Amaka C; Carlston, Colleen M; Carey, John C; Stewart, Grant S; Bacino, Carlos A; Campeau, Philippe M; Lee, Brendan | American journal of human genetics. | 2019 Mar 07; | 30773277 | |
| Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI. | Mock, Jason R; Dial, Catherine F; Tune, Miriya K; Norton, Dustin L; Martin, Jessica R; Gomez, John C; Hagan, Robert S; Dang, Hong; Doerschuk, Claire M | JCI insight. | 2019 Mar 21; | 30753170 | |
| Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche. | Salazar, Valerie S; Capelo, Luciane P; Cantù, Claudio; Zimmerli, Dario; Gosalia, Nehal; Pregizer, Steven; Cox, Karen; Ohte, Satoshi; Feigenson, Marina; Gamer, Laura; Nyman, Jeffry S; Carey, David J; Economides, Aris; Basler, Konrad; Rosen, Vicki | eLife. | 2019 Feb 08; | 30735122 | |
| Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities. | Stewart, Michelle; Lau, Petrina; Banks, Gareth; Bains, Rasneer Sonia; Castroflorio, Enrico; Oliver, Peter L; Dixon, Christine L; Kruer, Michael C; Kullmann, Dimitri M; Acevedo-Arozena, Abraham; Wells, Sara E; Corrochano, Silvia; Nolan, Patrick M | Disease models & mechanisms. | 2019 Feb 22; | 30692144 | |
| Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. | Zhou, Wenjun; He, Yanlin; Rehman, Atteeq U; Kong, Yan; Hong, Sungguan; Ding, Guolian; Yalamanchili, Hari Krishna; Wan, Ying-Wooi; Paul, Basil; Wang, Chuhan; Gong, Yingyun; Zhou, Wenxian; Liu, Hao; Dean, John; Scalais, Emmanuel; O'Driscoll, Mary; Morton, Jenny E V; DDD study; Hou, Xinguo; Wu, Qi; Tong, Qingchun; Liu, Zhandong; Liu, Pengfei; Xu, Yong; Sun, Zheng | Nature neuroscience. | 2019 02; | 30664766 | |
| Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis. | Goodwin, Leslie O; Splinter, Erik; Davis, Tiffany L; Urban, Rachel; He, Hao; Braun, Robert E; Chesler, Elissa J; Kumar, Vivek; van Min, Max; Ndukum, Juliet; Philip, Vivek M; Reinholdt, Laura G; Svenson, Karen; White, Jacqueline K; Sasner, Michael; Lutz, Cathleen; Murray, Stephen A | Genome research. | 2019 Mar; | 30659012 | |
| Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. | Monsivais, Diana; Peng, Jia; Kang, Yibin; Matzuk, Martin M | Proceedings of the National Academy of Sciences of the United States of America. | 2019 Feb 26; | 30655341 | |
| Using CRISPR/Cas9 engineering to generate a mouse with a conditional knockout allele for the promyelocytic leukemia zinc finger transcription factor. | Hai, Lan; Szwarc, Maria M; Lanza, Denise G; Heaney, Jason D; Lydon, John P | Genesis (New York, N.Y. : 2000). | 2019 Mar; | 30628160 | |
| Generating mouse models for biomedical research: technological advances. | Gurumurthy, Channabasavaiah B; Lloyd, Kevin C Kent | Disease models & mechanisms. | 2019 01 08; | 30626588 | |
| Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. | Lo Re, Oriana; Mazza, Tommaso; Vinciguerra, Manlio | Frontiers in genetics. | 2018; | 30619475 | |
| KCa1.1 and Kv1.3 channels regulate the interactions between fibroblast-like synoviocytes and T lymphocytes during rheumatoid arthritis. | Tanner, Mark R; Pennington, Michael W; Chauhan, Satendra S; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine | Arthritis research & therapy. | 2019 Jan 07; | 30612588 | |
| Identification of genes required for eye development by high-throughput screening of mouse knockouts. | Moore, Bret A; Leonard, Brian C; Sebbag, Lionel; Edwards, Sydney G; Cooper, Ann; Imai, Denise M; Straiton, Ewan; Santos, Luis; Reilly, Christopher; Griffey, Stephen M; Bower, Lynette; Clary, David; Mason, Jeremy; Roux, Michel J; Meziane, Hamid; Herault, Yann; International Mouse Phenotyping Consortium; McKerlie, Colin; Flenniken, Ann M; Nutter, Lauryl M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammed; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gallegos, Juan J; Seavitt, John R; Heaney, Jason D; Beaudet, Arthur L; Dickinson, Mary E; Justice, Monica J; Philip, Vivek; Kumar, Vivek; Svenson, Karen L; Braun, Robert E; Wells, Sara; Cater, Heather; Stewart, Michelle; Clementson-Mobbs, Sharon; Joynson, Russell; Gao, Xiang; Suzuki, Tomohiro; Wakana, Shigeharu; Smedley, Damian; Seong, J K; Tocchini-Valentini, Glauco; Moore, Mark; Fletcher, Colin; Karp, Natasha; Ramirez-Solis, Ramiro; White, Jacqueline K; de Angelis, Martin Hrabe; Wurst, Wolfgang; Thomasy, Sara M; Flicek, Paul; Parkinson, Helen; Brown, Steve D M; Meehan, Terrence F; Nishina, Patsy M; Murray, Stephen A; Krebs, Mark P; Mallon, Ann-Marie; Lloyd, K C Kent; Murphy, Christopher J; Moshiri, Ala | Communications biology. | 2018; | 30588515 | |
| Gi/o protein-coupled receptors in dopamine neurons inhibit the sodium leak channel NALCN. | Philippart, Fabian; Khaliq, Zayd M | eLife. | 2018 12 17; | 30556810 | |
| Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice. | Xu, Wenqiong; Zhou, Hongyi; Xuan, Hongzhuan; Saha, Pradip; Wang, Gongxian; Chen, Weiqin | Molecular and cellular endocrinology. | 2019 Feb 15; | 30521848 | |
| Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. | Kim, Hyeongseok; Kim, Yeong Gi; Choi, Wonsuk; Moon, Joon Ho; Hwang, Inseon; Kim, Kyuho; Yadav, Vijay K; Karsenty, Gerard; Jeong, Ji-Seon; Kim, Hail | Scientific reports. | 2018 Dec 05; | 30518775 | |
| Utility of HbA1c assessment in people with diabetes awaiting liver transplantation. | Bhattacharjee, D; Vracar, S; Round, R A; Nightingale, P G; Williams, J A; Gkoutos, G V; Stratton, I M; Parker, R; Luzio, S D; Webber, J; Manley, S E; Roberts, G A; Ghosh, S | Diabetic medicine : a journal of the British Diabetic Association. | 2018 Nov 26; | 30474191 | |
| IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections. | Shepardson, Kelly M; Larson, Kyle; Johns, Laura L; Stanek, Kayla; Cho, Hanbyul; Wellham, Julia; Henderson, Haley; Rynda-Apple, Agnieszka | Frontiers in immunology. | 2018; | 30473701 | |
| WDFY4 is required for cross-presentation in response to viral and tumor antigens. | Theisen, Derek J; Davidson 4th, Jesse T; Briseño, Carlos G; Gargaro, Marco; Lauron, Elvin J; Wang, Qiuling; Desai, Pritesh; Durai, Vivek; Bagadia, Prachi; Brickner, Joshua R; Beatty, Wandy L; Virgin, Herbert W; Gillanders, William E; Mosammaparast, Nima; Diamond, Michael S; Sibley, L David; Yokoyama, Wayne; Schreiber, Robert D; Murphy, Theresa L; Murphy, Kenneth M | Science (New York, N.Y.). | 2018 11 09; | 30409884 | |
| The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. | Panda, Swarupa; Gekara, Nelson O | Nature communications. | 2018 11 07; | 30405132 | |
| FAM92A Underlies Nonsyndromic Postaxial Polydactyly in Humans and an Abnormal Limb and Digit Skeletal Phenotype in Mice. | Schrauwen, Isabelle; Giese, Arnaud Pj; Aziz, Abdul; Lafont, David Tino; Chakchouk, Imen; Santos-Cortez, Regie Lyn P; Lee, Kwanghyuk; Acharya, Anushree; Khan, Falak Sher; Ullah, Asmat; Nickerson, Deborah A; Bamshad, Michael J; Ali, Ghazanfar; Riazuddin, Saima; Ansar, Muhammad; Ahmad, Wasim; Ahmed, Zubair M; Leal, Suzanne M | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. | 2019 Feb; | 30395363 | |
| Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism. | Tassi, Elena; Garman, Khalid A; Schmidt, Marcel O; Ma, Xiaoting; Kabbara, Khaled W; Uren, Aykut; Tomita, York; Goetz, Regina; Mohammadi, Moosa; Wilcox, Christopher S; Riegel, Anna T; Carlstrom, Mattias; Wellstein, Anton | Scientific reports. | 2018 Oct 29; | 30374109 | |
| Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia. | Sundberg, John P; Shen, Tong; Fiehn, Oliver; Rice, Robert H; Silva, Kathleen A; Kennedy, Victoria E; Gott, Nicholas E; Dionne, Louise A; Bechtold, Lesley S; Murray, Stephen A; Kuiper, Raoul; Pratt, C Herbert | PloS one. | 2018; | 30372477 | |
| CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. | Pang, Paul D; Alsina, Katherina M; Cao, Shuyi; Koushik, Amrita B; Wehrens, Xander H T; Cooper, Thomas A | Journal of the American Heart Association. | 2018 Oct 02; | 30371314 | |
| Haploinsufficiency of autism spectrum disorder candidate gene NUAK1 impairs cortical development and behavior in mice. | Courchet, Virginie; Roberts, Amanda J; Meyer-Dilhet, Géraldine; Del Carmine, Peggy; Lewis Jr, Tommy L; Polleux, Franck; Courchet, Julien | Nature communications. | 2018 10 16; | 30327473 | |
| Comparison of cryosurvival and spermatogenesis efficiency of cryopreserved neonatal mouse testicular tissue between three vitrification protocols and controlled-rate freezing. | Yildiz, Cengiz; Mullen, Brendan; Jarvi, Keith; McKerlie, Colin; Lo, Kirk C | Cryobiology. | 2018 10; | 30195700 | |
| Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. | Szwarc, Maria M; Kommagani, Ramakrishna; Putluri, Vasanta; Dubrulle, Julien; Stossi, Fabio; Mancini, Michael A; Coarfa, Cristian; Lanz, Rainer B; Putluri, Nagireddy; DeMayo, Francesco J; Lydon, John P; O'Malley, Bert W | Scientific reports. | 2018 Sep 03; | 30177747 | |
| Rapid and Integrative Discovery of Retina Regulatory Molecules. | Albrecht, Nicholas E; Alevy, Jonathan; Jiang, Danye; Burger, Courtney A; Liu, Brian I; Li, Fenge; Wang, Julia; Kim, Seon-Young; Hsu, Chih-Wei; Kalaga, Sowmya; Udensi, Uchechukwu; Asomugha, Chinwe; Bohat, Ritu; Gaspero, Angelina; Justice, Monica J; Westenskow, Peter D; Yamamoto, Shinya; Seavitt, John R; Beaudet, Arthur L; Dickinson, Mary E; Samuel, Melanie A | Cell reports. | 2018 Aug 28; | 30157441 | |
| Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. | Lee, Sang H; Shin, Seung Min; Zhong, Peng; Kim, Hyun-Taek; Kim, Dong-Il; Kim, June Myoung; Do Heo, Won; Kim, Dae-Won; Yeo, Chang-Yeol; Kim, Cheol-Hee; Liu, Qing-Song | Nature communications. | 2018 08 24; | 30143647 | |
| Ndr kinases regulate retinal interneuron proliferation and homeostasis. | Léger, Hélène; Santana, Evelyn; Leu, N Adrian; Smith, Eliot T; Beltran, William A; Aguirre, Gustavo D; Luca, Francis C | Scientific reports. | 2018 Aug 22; | 30135513 | |
| The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation. | Muñoz-Fuentes, Violeta; Cacheiro, Pilar; Meehan, Terrence F; Aguilar-Pimentel, Juan Antonio; Brown, Steve D M; Flenniken, Ann M; Flicek, Paul; Galli, Antonella; Mashhadi, Hamed Haseli; Hrab? de Angelis, Martin; Kim, Jong Kyoung; Lloyd, K C Kent; McKerlie, Colin; Morgan, Hugh; Murray, Stephen A; Nutter, Lauryl M J; Reilly, Patrick T; Seavitt, John R; Seong, Je Kyung; Simon, Michelle; Wardle-Jones, Hannah; Mallon, Ann-Marie; Smedley, Damian; Parkinson, Helen E; IMPC consortium | Conservation genetics (Print). | 2018; | 30100824 | |
| Characterization of Tissue Plasminogen Activator Expression and Trafficking in the Adult Murine Brain. | Stevenson, Tamara K; Lawrence, Daniel A | eNeuro. | 2018 Jul-Aug; | 30090852 | |
| Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy. | Napoli, Eleonora; Song, Gyu; Panoutsopoulos, Alexios; Riyadh, M Asrafuzzaman; Kaushik, Gaurav; Halmai, Julian; Levenson, Richard; Zarbalis, Konstantinos S; Giulivi, Cecilia | Scientific reports. | 2018 Jul 27; | 30054502 | |
| Engineering Point Mutant and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease. | Gertsenstein, Marina; Nutter, Lauryl M J | Current protocols in mouse biology. | 2018 Mar; | 30040228 | |
| TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. | Cheung, Sin Ying; Henrot, Matthias; Al-Saad, Mohammad; Baumann, Matthias; Muller, Heiko; Unger, Anke; Rubaiy, Hussein N; Mathar, Ilka; Dinkel, Klaus; Nussbaumer, Peter; Klebl, Bert; Freichel, Marc; Rode, Baptiste; Trainor, Sebastian; Clapcote, Steven J; Christmann, Mathias; Waldmann, Herbert; Abbas, Syed Khawar; Beech, David J; Vasudev, Naveen S | Oncotarget. | 2018 Jul 03; | 30038709 | |
| Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. | Paulo, Esther; Wu, Dongmei; Wang, Yangmeng; Zhang, Yun; Wu, Yixuan; Swaney, Danielle L; Soucheray, Margaret; Jimenez-Morales, David; Chawla, Ajay; Krogan, Nevan J; Wang, Biao | Scientific reports. | 2018 Jul 20; | 30030465 | |
| Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. | Recio, Carlota; Lucy, Daniel; Purvis, Gareth S D; Iveson, Poppy; Zeboudj, Lynda; Iqbal, Asif J; Lin, Daniel; O'Callaghan, Chris; Davison, Lucy; Griesbach, Esther; Russell, Angela J; Wynne, Graham M; Dib, Lea; Monaco, Claudia; Greaves, David R | Frontiers in immunology. | 2018; | 29973940 | |
| Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis. | Singh, Ravi K; Kolonin, Arseniy M; Fiorotto, Marta L; Cooper, Thomas A | Cell reports. | 2018 Jul 03; | 29972780 | |
| C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function. | Raghunathan, Suchi; Reynolds, Corey L; Schwartz, Robert J; Stewart, M David; McConnell, Bradley K | Fundamental & clinical pharmacology. | 2018 Jun 30; | 29959870 | |
| Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants. | Codner, Gemma F; Mianné, Joffrey; Caulder, Adam; Loeffler, Jorik; Fell, Rachel; King, Ruairidh; Allan, Alasdair J; Mackenzie, Matthew; Pike, Fran J; McCabe, Christopher V; Christou, Skevoulla; Joynson, Sam; Hutchison, Marie; Stewart, Michelle E; Kumar, Saumya; Simon, Michelle M; Agius, Loranne; Anstee, Quentin M; Volynski, Kirill E; Kullmann, Dimitri M; Wells, Sara; Teboul, Lydia | BMC biology. | 2018 Jun 21; | 29925374 | |
| Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles. | Lanza, Denise G; Gaspero, Angelina; Lorenzo, Isabel; Liao, Lan; Zheng, Ping; Wang, Ying; Deng, Yu; Cheng, Chonghui; Zhang, Chuansheng; Seavitt, John R; DeMayo, Francesco J; Xu, Jianming; Dickinson, Mary E; Beaudet, Arthur L; Heaney, Jason D | BMC biology. | 2018 Jun 21; | 29925370 | |
| Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain. | Carbajosa, Guillermo; Malki, Karim; Lawless, Nathan; Wang, Hong; Ryder, John W; Wozniak, Eva; Wood, Kristie; Mein, Charles A; Dobson, Richard J B; Collier, David A; O'Neill, Michael J; Hodges, Angela K; Newhouse, Stephen J | Neurobiology of aging. | 2018 09; | 29906661 | |
| FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex. | Künzel, Ulrike; Grieve, Adam Graham; Meng, Yao; Sieber, Boris; Cowley, Sally A; Freeman, Matthew | eLife. | 2018 06 13; | 29897336 | |
| Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity. | Zhang, Ming-Dong; Su, Jie; Adori, Csaba; Cinquina, Valentina; Malenczyk, Katarzyna; Girach, Fatima; Peng, Changgeng; Ernfors, Patrik; Löw, Peter; Borgius, Lotta; Kiehn, Ole; Watanabe, Masahiko; Uhlén, Mathias; Mitsios, Nicholas; Mulder, Jan; Harkany, Tibor; Hökfelt, Tomas | The Journal of clinical investigation. | 2018 08 31; | 29893745 | |
| Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment. | Sukumaran, Sujita; Watanabe, Norihiro; Bajgain, Pradip; Raja, Kanchana; Mohammed, Somala; Fisher, William E; Brenner, Malcolm K; Leen, Ann M; Vera, Juan F | Cancer discovery. | 2018 Aug; | 29880586 | |
| High-resolution ?CT of a mouse embryo using a compact laser-driven X-ray betatron source. | Cole, Jason M; Symes, Daniel R; Lopes, Nelson C; Wood, Jonathan C; Poder, Kristjan; Alatabi, Saleh; Botchway, Stanley W; Foster, Peta S; Gratton, Sarah; Johnson, Sara; Kamperidis, Christos; Kononenko, Olena; De Lazzari, Michael; Palmer, Charlotte A J; Rusby, Dean; Sanderson, Jeremy; Sandholzer, Michael; Sarri, Gianluca; Szoke-Kovacs, Zsombor; Teboul, Lydia; Thompson, James M; Warwick, Jonathan R; Westerberg, Henrik; Hill, Mark A; Norris, Dominic P; Mangles, Stuart P D; Najmudin, Zulfikar | Proceedings of the National Academy of Sciences of the United States of America. | 2018 06 19; | 29871946 | |
| A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice. | Moore, Bret A; Roux, Michel J; Sebbag, Lionel; Cooper, Ann; Edwards, Sydney G; Leonard, Brian C; Imai, Denise M; Griffey, Stephen; Bower, Lynette; Clary, Dave; Lloyd, K C Kent; Hérault, Yann; Thomasy, Sara M; Murphy, Christopher J; Moshiri, Ala | Investigative ophthalmology & visual science. | 2018 May 01; | 29847629 | |
| Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. | Yao, Chunxia; Veleva, Tina; Scott Jr, Larry; Cao, Shuyi; Li, Luge; Chen, Gong; Jeyabal, Prince; Pan, Xiaolu; Alsina, Katherina M; Abu-Taha Dr, Issam; Ghezelbash, Shokoufeh; Reynolds, Corey L; Shen, Ying H; LeMaire, Scott A; Schmitz, Wilhelm; Müller, Frank U; El-Armouche, Ali; Tony Eissa, N; Beeton, Christine; Nattel, Stanley; Wehrens, Xander H T; Dobrev, Dobromir; Li, Na | Circulation. | 2018 11 13; | 29802206 | |
| Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1. | Morriss, Ginny R; Rajapakshe, Kimal; Huang, Shixia; Coarfa, Cristian; Cooper, Thomas A | Human molecular genetics. | ; | 29771332 | |
| Efficient mouse genome engineering by CRISPR-EZ technology. | Modzelewski, Andrew J; Chen, Sean; Willis, Brandon J; Lloyd, K C Kent; Wood, Joshua A; He, Lin | Nature protocols. | 2018 06; | 29748649 | |
| SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program. | Ratnadiwakara, Madara; Archer, Stuart K; Dent, Craig I; Ruiz De Los Mozos, Igor; Beilharz, Traude H; Knaupp, Anja S; Nefzger, Christian M; Polo, Jose M; Anko, Minna-Liisa | eLife. | 2018 05 09; | 29741478 | |
| Adar3 Is Involved in Learning and Memory in Mice. | Mladenova, Dessislava; Barry, Guy; Konen, Lyndsey M; Pineda, Sandy S; Guennewig, Boris; Avesson, Lotta; Zinn, Raphael; Schonrock, Nicole; Bitar, Maina; Jonkhout, Nicky; Crumlish, Lauren; Kaczorowski, Dominik C; Gong, Andrew; Pinese, Mark; Franco, Gloria R; Walkley, Carl R; Vissel, Bryce; Mattick, John S | Frontiers in neuroscience. | 2018; | 29719497 | |
| Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. | De Pace, Raffaella; Skirzewski, Miguel; Damme, Markus; Mattera, Rafael; Mercurio, Jeffrey; Foster, Arianne M; Cuitino, Loreto; Jarnik, Michal; Hoffmann, Victoria; Morris, H Douglas; Han, Tae-Un; Mancini, Grazia M S; Buonanno, Andrés; Bonifacino, Juan S | PLoS genetics. | 2018 04; | 29698489 | |
| Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. | Xiao, Yang; Hill, Matthew C; Zhang, Min; Martin, Thomas J; Morikawa, Yuka; Wang, Suya; Moise, Alexander R; Wythe, Joshua D; Martin, James F | Developmental cell. | 2018 04 23; | 29689192 | |
| Pathogenic Effects of IFIT2 and Interferon-? during Fatal Systemic Candida albicans Infection. | Stawowczyk, Marcin; Naseem, Shamoon; Montoya, Valeria; Baker, Darren P; Konopka, James; Reich, Nancy C | mBio. | 2018 04 17; | 29666281 | |
| IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. | You, Ran; DeMayo, Francesco J; Liu, Jian; Cho, Sung-Nam; Burt, Bryan M; Creighton, Chad J; Casal, Roberto F; Lazarus, Donald R; Lu, Wen; Tung, Hui-Ying; Yuan, Xiaoyi; Hill-McAlester, Andrea; Kim, Myunghoo; Perusich, Sarah; Cornwell, Loraine; Rosen, Daniel; Song, Li-Zhen; Paust, Silke; Diehl, Gretchen; Corry, David; Kheradmand, Farrah | Cancer immunology research. | 2018 06; | 29653981 | |
| Renal proteomic analysis of RGC-32 knockout mice reveals the potential mechanism of RGC-32 in regulating cell cycle. | Hu, Yu-Jie; Zhou, Qian; Li, Zhu-Yin; Feng, Dan; Sun, Lei; Shen, Yun-Lin; Huang, Wen-Yan | American journal of translational research. | 2018; | 29636874 | |
| High-throughput mouse phenomics for characterizing mammalian gene function. | Brown, Steve D M; Holmes, Chris C; Mallon, Ann-Marie; Meehan, Terrence F; Smedley, Damian; Wells, Sara | Nature reviews. Genetics. | 2018 Jun; | 29626206 | |
| The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia. | Jordan, Valerie K; Beck, Tyler F; Hernandez-Garcia, Andres; Kundert, Peter N; Kim, Bum-Jun; Jhangiani, Shalini N; Gambin, Tomasz; Starkovich, Molly; Punetha, Jaya; Paine, Ingrid S; Posey, Jennifer E; Li, Alexander H; Muzny, Donna; Hsu, Chih-Wei; Lashua, Amber J; Sun, Xin; Fernandes, Caraciolo J; Dickinson, Mary E; Lally, Kevin P; Gibbs, Richard A; Boerwinkle, Eric; Lupski, James R; Scott, Daryl A | Human molecular genetics. | 2018 06 15; | 29618029 | |
| Response to ''Unexpected mutations after CRISPR-Cas9 editing in vivo''. | Nutter, Lauryl M J; Heaney, Jason D; Lloyd, K C Kent; Murray, Stephen A; Seavitt, John R; Skarnes, William C; Teboul, Lydia; Brown, Steve D M; Moore, Mark | Nature methods. | 2018 Apr; | 29600991 | |
| Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice. | Wang, Ke-Yong; Yamada, Sohsuke; Izumi, Hiroto; Tsukamoto, Manabu; Nakashima, Tamiji; Tasaki, Takashi; Guo, Xin; Uramoto, Hidetaka; Sasaguri, Yasuyuki; Kohno, Kimitoshi | PloS one. | 2018; | 29596490 | |
| Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2). | Zhong, Li; Wang, Zongqi; Wang, Daxin; Wang, Zhe; Martens, Yuka A; Wu, Linbei; Xu, Ying; Wang, Kai; Li, Jianguo; Huang, Ruizhi; Can, Dan; Xu, Huaxi; Bu, Guojun; Chen, Xiao-Fen | Molecular neurodegeneration. | 2018 03 27; | 29587871 | |
| Unexplored therapeutic opportunities in the human genome. | Oprea, Tudor I; Bologa, Cristian G; Brunak, Søren; Campbell, Allen; Gan, Gregory N; Gaulton, Anna; Gomez, Shawn M; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L; Karlson, Anneli; Leach, Andrew R; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Steven L; McManus, Michael T; Meehan, Terrence F; von Mering, Christian; Muthas, Daniel; Nguyen, Dac-Trung; Overington, John P; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L; Schürer, Stephan C; Simeonov, Anton; Sklar, Larry A; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Du?ica; Waller, Anna; Westergaard, David; Yang, Jeremy J; Zahoránszky-Köhalmi, Gergely | Nature reviews. Drug discovery. | 2018 May; | 29567993 | |
| Dynamic Imaging of Mouse Embryos and Cardiodynamics in Static Culture. | Lopez 3rd, Andrew L; Larina, Irina V | Methods in molecular biology (Clifton, N.J.). | 2018; | 29564760 | |
| Loss of the Intellectual Disability and Autism Gene Cc2d1a and Its Homolog Cc2d1b Differentially Affect Spatial Memory, Anxiety, and Hyperactivity. | Zamarbide, Marta; Oaks, Adam W; Pond, Heather L; Adelman, Julia S; Manzini, M Chiara | Frontiers in genetics. | 2018; | 29552027 | |
| The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining. | Li, Conglei; Irrazabal, Thergiory; So, Clare C; Berru, Maribel; Du, Likun; Lam, Evelyn; Ling, Alexanda K; Gommerman, Jennifer L; Pan-Hammarström, Qiang; Martin, Alberto | Nature communications. | 2018 03 08; | 29520062 | |
| Contribution of metabolic disease to bone fragility in MAGP1-deficient mice. | Turecamo, S E; Walji, T A; Broekelmann, T J; Williams, J W; Ivanov, S; Wee, N K; Procknow, J D; McManus, M R; Randolph, G J; Scheller, E L; Mecham, R P; Craft, C S | Matrix biology : journal of the International Society for Matrix Biology. | 2018 04; | 29519758 | |
| Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. | Ronning, Kaitryn E; Allina, Gabriel Peinado; Miller, Eric B; Zawadzki, Robert J; Pugh Jr, Edward N; Herrmann, Rolf; Burns, Marie E | Experimental eye research. | 2018 06; | 29518352 | |
| TRPV6, TRPM6 and TRPM7 Do Not Contribute to Hair-Cell Mechanotransduction. | Morgan, Clive P; Zhao, Hongyu; LeMasurier, Meredith; Xiong, Wei; Pan, Bifeng; Kazmierczak, Piotr; Avenarius, Matthew R; Bateschell, Michael; Larisch, Ruby; Ricci, Anthony J; Müller, Ulrich; Barr-Gillespie, Peter G | Frontiers in cellular neuroscience. | 2018; | 29515374 | |
| SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. | Matt, Lucas; Kirk, Lyndsey M; Chenaux, George; Speca, David J; Puhger, Kyle R; Pride, Michael C; Qneibi, Mohammad; Haham, Tomer; Plambeck, Kristopher E; Stern-Bach, Yael; Silverman, Jill L; Crawley, Jacqueline N; Hell, Johannes W; Díaz, Elva | Cell reports. | 2018 Feb 27; | 29490264 | |
| Unexplored therapeutic opportunities in the human genome. | Oprea, Tudor I; Bologa, Cristian G; Brunak, Søren; Campbell, Allen; Gan, Gregory N; Gaulton, Anna; Gomez, Shawn M; Guha, Rajarshi; Hersey, Anne; Holmes, Jayme; Jadhav, Ajit; Jensen, Lars Juhl; Johnson, Gary L; Karlson, Anneli; Leach, Andrew R; Ma'ayan, Avi; Malovannaya, Anna; Mani, Subramani; Mathias, Stephen L; McManus, Michael T; Meehan, Terrence F; von Mering, Christian; Muthas, Daniel; Nguyen, Dac-Trung; Overington, John P; Papadatos, George; Qin, Jun; Reich, Christian; Roth, Bryan L; Schürer, Stephan C; Simeonov, Anton; Sklar, Larry A; Southall, Noel; Tomita, Susumu; Tudose, Ilinca; Ursu, Oleg; Vidovic, Du?ica; Waller, Anna; Westergaard, David; Yang, Jeremy J; Zahoránszky-Köhalmi, Gergely | Nature reviews. Drug discovery. | 2018 May; | 29472638 | |
| Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic Angiogenesis. | Fan, Yanbo; Lu, Haocheng; Liang, Wenying; Garcia-Barrio, Minerva T; Guo, Yanhong; Zhang, Ji; Zhu, Tianqing; Hao, Yibai; Zhang, Jifeng; Chen, Y Eugene | Circulation research. | 2018 Mar 30; | 29467198 | |
| Correction to: Characterization of bone morphology in CCN5/WISP2 knockout mice. | Jiang, Jie; Zhao, Gexin; Lyons, Karen M | Journal of cell communication and signaling. | 2018 Mar; | 29455304 | |
| Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis. | Tanner, Mark R; Pennington, Michael W; Chamberlain, Brayden H; Huq, Redwan; Gehrmann, Elizabeth J; Laragione, Teresina; Gulko, Pércio S; Beeton, Christine | The Journal of pharmacology and experimental therapeutics. | 2018 May; | 29453198 | |
| A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model. | Wellard, Stephen R; Hopkins, Jessica; Jordan, Philip W | Journal of visualized experiments : JoVE | 2018 02 06 | 29443055 | |
| Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis. | Wardhana, Donytra Arby; Ikeda, Koji; Barinda, Agian Jeffilano; Nugroho, Dhite Bayu; Qurania, Kikid Rucira; Yagi, Keiko; Miyata, Keishi; Oike, Yuichi; Hirata, Ken-Ichi; Emoto, Noriaki | Proceedings of the National Academy of Sciences of the United States of America. | 2018 02 13; | 29386390 | |
| Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis. | DaSilva-Arnold, Sonia C; Thyagarajan, Anita; Seymour, Leroy J; Yi, Qiaofang; Bradish, Joshua R; Al-Hassani, Mohammed; Zhou, Hongming; Perdue, Nikolajs J; Nemeth, Val; Krbanjevic, Aleksandar; Serezani, Ana P M; Olson, Matthew R; Spandau, Dan F; Travers, Jeffrey B; Kaplan, Mark H; Turner, Matthew J | Archives of dermatological research. | 2018 Apr; | 29368135 | |
| Identification of genetic elements in metabolism by high-throughput mouse phenotyping. | Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershäuser, Monja; Brommage, Robert; Meehan, Terrence F; Mason, Jeremy; Haselimashhadi, Hamed; IMPC Consortium; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J; White, Jacqueline K; Sorg, Tania; Champy, Marie-France; Bower, Lynette R; Reynolds, Corey L; Flenniken, Ann M; Murray, Stephen A; Nutter, Lauryl M J; Svenson, Karen L; West, David; Tocchini-Valentini, Glauco P; Beaudet, Arthur L; Bosch, Fatima; Braun, Robert B; Dobbie, Michael S; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A; Kent Lloyd, K C; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D; Tschöp, Matthias H; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas; Hrabe de Angelis, Martin | Nature communications. | 2018 Jan 18; | 29348434 | |
| Impact of Swiprosin-1/Efhd2 on Adult Hippocampal Neurogenesis. | Regensburger, Martin; Prots, Iryna; Reimer, Dorothea; Brachs, Sebastian; Loskarn, Sandra; Lie, Dieter Chichung; Mielenz, Dirk; Winner, Beate | Stem cell reports. | 2018 02 13; | 29337116 | |
| A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. | Abdelhamed, Zakia; Vuong, Shawn M; Hill, Lauren; Shula, Crystal; Timms, Andrew; Beier, David; Campbell, Kenneth; Mangano, Francesco T; Stottmann, Rolf W; Goto, June | Development (Cambridge, England). | 2018 01 09; | 29317443 | |
| Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice. | Kidana, Kiwami; Tatebe, Takuya; Ito, Kaori; Hara, Norikazu; Kakita, Akiyoshi; Saito, Takashi; Takatori, Sho; Ouchi, Yasuyoshi; Ikeuchi, Takeshi; Makino, Mitsuhiro; Saido, Takaomi C; Akishita, Masahiro; Iwatsubo, Takeshi; Hori, Yukiko; Tomita, Taisuke | EMBO molecular medicine. | 2018 03; | 29311134 | |
| Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population. | Huang, Lei; Wu, Kuo-Ho; Zhang, Liyong; Wang, Qinchuan; Tang, Shuangbo; Wu, Qiuping; Jiang, Pei-Hsiu; Lin, Jim Jung-Ching; Guo, Jian; Wang, Lin; Loh, Shih-Hurng; Cheng, Jianding | Journal of the American Heart Association. | 2018 01 06; | 29306897 | |
| Robust model-based analysis of single-particle tracking experiments with Spot-On. | Hansen, Anders S; Woringer, Maxime; Grimm, Jonathan B; Lavis, Luke D; Tjian, Robert; Darzacq, Xavier | eLife. | 2018 Jan 04; | 29300163 | |
| Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. | Pol, Arjan; Renkema, G Herma; Tangerman, Albert; Winkel, Edwin G; Engelke, Udo F; de Brouwer, Arjan P M; Lloyd, Kent C; Araiza, Renee S; van den Heuvel, Lambert; Omran, Heymut; Olbrich, Heike; Oude Elberink, Marijn; Gilissen, Christian; Rodenburg, Richard J; Sass, Jörn Oliver; Schwab, K Otfried; Schäfer, Hendrik; Venselaar, Hanka; Sequeira, J Silvia; Op den Camp, Huub J M; Wevers, Ron A | Nature genetics. | 2018 Jan; | 29255262 | |
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| SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity. | Quick, Ann P; Wang, Qiongling; Philippen, Leonne E; Barreto-Torres, Giselle; Chiang, David Y; Beavers, David; Wang, Guoliang; Khalid, Maha; Reynolds, Julia O; Campbell, Hannah M; Showell, Jordan; McCauley, Mark D; Scholten, Arjen; Wehrens, Xander H T | Circulation research. | 2017 Jan 06; | 27729468 | |
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| Noncontact Elastic Wave Imaging Optical Coherence Elastography for Evaluating Changes in Corneal Elasticity Due to Crosslinking. | Singh, Manmohan; Li, Jiasong; Vantipalli, Srilatha; Wang, Shang; Han, Zhaolong; Nair, Achuth; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V | IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. | 2016 May-Jun; | 27547022 | |
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| Cryorecovery of Mouse Sperm by Different IVF Methods Using MBCD and GSH. | Li, Ming-Wen; Glass, Olivia C; Zarrabi, Jasmin; Baker, Lisa N; Lloyd, K C Kent | Journal of fertilization in vitro. | 2016 May; | 27413624 | |
| Evaluating the Effects of Riboflavin/UV-A and Rose-Bengal/Green Light Cross-Linking of the Rabbit Cornea by Noncontact Optical Coherence Elastography. | Singh, Manmohan; Li, Jiasong; Han, Zhaolong; Vantipalli, Srilatha; Liu, Chih-Hao; Wu, Chen; Raghunathan, Raksha; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V | Investigative ophthalmology & visual science. | 2016 07 01; | 27409461 | |
| Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. | Haeussler, Maximilian; Schönig, Kai; Eckert, Hélène; Eschstruth, Alexis; Mianné, Joffrey; Renaud, Jean-Baptiste; Schneider-Maunoury, Sylvie; Shkumatava, Alena; Teboul, Lydia; Kent, Jim; Joly, Jean-Stephane; Concordet, Jean-Paul | Genome biology. | 2016 Jul 05; | 27380939 | |
| Applicability, usability, and limitations of murine embryonic imaging with optical coherence tomography and optical projection tomography. | Singh, Manmohan; Raghunathan, Raksha; Piazza, Victor; Davis-Loiacono, Anjul M; Cable, Alex; Vedakkan, Tegy J; Janecek, Trevor; Frazier, Michael V; Nair, Achuth; Wu, Chen; Larina, Irina V; Dickinson, Mary E; Larin, Kirill V | Biomedical optics express. | 2016 Jun 01; | 27375945 | |
| Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. | Tao, Ge; Kahr, Peter C; Morikawa, Yuka; Zhang, Min; Rahmani, Mahdis; Heallen, Todd R; Li, Lele; Sun, Zhao; Olson, Eric N; Amendt, Brad A; Martin, James F | Nature. | 2016 Jun 2; | 27251288 | |
| CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities. | Leduc, Magalie S; Niu, Zhiyv; Bi, Weimin; Zhu, Wenmiao; Miloslavskaya, Irene; Chiang, Theodore; Streff, Haley; Seavitt, John R; Murray, Stephen A; Eng, Christine; Chan, Audrey; Yang, Yaping; Lalani, Seema R | American journal of medical genetics. Part A. | 2016 Aug; | 27250922 | |
| Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. | Madeo, Marianna; Stewart, Michelle; Sun, Yuyang; Sahir, Nadia; Wiethoff, Sarah; Chandrasekar, Indra; Yarrow, Anna; Rosenfeld, Jill A; Yang, Yaping; Cordeiro, Dawn; McCormick, Elizabeth M; Muraresku, Colleen C; Jepperson, Tyler N; McBeth, Lauren J; Seidahmed, Mohammed Zain; El Khashab, Heba Y; Hamad, Muddathir; Azzedine, Hamid; Clark, Karl; Corrochano, Silvia; Wells, Sara; Elting, Mariet W; Weiss, Marjan M; Burn, Sabrina; Myers, Angela; Landsverk, Megan; Crotwell, Patricia L; Waisfisz, Quinten; Wolf, Nicole I; Nolan, Patrick M; Padilla-Lopez, Sergio; Houlden, Henry; Lifton, Richard; Mane, Shrikant; Singh, Brij B; Falk, Marni J; Mercimek-Mahmutoglu, Saadet; Bilguvar, Kaya; Salih, Mustafa A; Acevedo-Arozena, Abraham; Kruer, Michael C | American journal of human genetics. | 2016 Jun 2; | 27236917 | |
| Optical coherence tomography for embryonic imaging: a review. | Raghunathan, Raksha; Singh, Manmohan; Dickinson, Mary E; Larin, Kirill V | Journal of biomedical optics. | 2016 May 01; | 27228503 | |
| Rapid, noninvasive quantitation of skin disease in systemic sclerosis using optical coherence elastography. | Du, Yong; Liu, Chih-Hao; Lei, Ling; Singh, Manmohan; Li, Jiasong; Hicks, M John; Larin, Kirill V; Mohan, Chandra | Journal of biomedical optics. | 2016 Apr 30; | 27048877 | |
| Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice. | Shaheen, Ranad; Anazi, Shams; Ben-Omran, Tawfeg; Seidahmed, Mohammed Zain; Caddle, L Brianna; Palmer, Kristina; Ali, Rehab; Alshidi, Tarfa; Hagos, Samya; Goodwin, Leslie; Hashem, Mais; Wakil, Salma M; Abouelhoda, Mohamed; Colak, Dilek; Murray, Stephen A; | American journal of human genetics. | 2016 Apr 7; | 27018474 | |
| Four-dimensional live imaging of hemodynamics in mammalian embryonic heart with Doppler optical coherence tomography. | Wang, Shang; Lakomy, David S; Garcia, Monica D; Lopez 3rd, Andrew L; Larin, Kirill V; Larina, Irina V | Journal of biophotonics. | 2016 Aug; | 26996292 | |
| Optical coherence tomography as a tool for real-time visual feedback and biomechanical assessment of dermal filler injections: preliminary results in a pig skin model. | Singh, Manmohan; Wang, Shang; Yee, Richard W; Larin, Kirill V | Experimental dermatology. | 2016 06; | 26910121 | |
| Reporting phenotypes in mouse models when considering body size as a potential confounder. | Oellrich, Anika; Meehan, Terrence F; Parkinson, Helen; Sarntivijai, Sirarat; White, Jacqueline K; Karp, Natasha A | Journal of biomedical semantics | 2016 | 26865945 | |
| Rotational imaging optical coherence tomography for full-body mouse embryonic imaging. | Wu, Chen; Sudheendran, Narendran; Singh, Manmohan; Larina, Irina V; Dickinson, Mary E; Larin, Kirill V | Journal of biomedical optics. | 2016 Feb; | 26848543 | |
| Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. | West, David B; Engelhard, Eric K; Adkisson, Michael; Nava, A J; Kirov, Julia V; Cipollone, Andreanna; Willis, Brandon; Rapp, Jared; de Jong, Pieter J; Lloyd, Kent C | PLoS genetics. | 2016 Feb; | e1005691 | 26839965 |
| Classifying murine glomerulonephritis using optical coherence tomography and optical coherence elastography. | Liu, Chih-Hao; Du, Yong; Singh, Manmohan; Wu, Chen; Han, Zhaolong; Li, Jiasong; Chang, Anthony; Mohan, Chandra; Larin, Kirill V | Journal of biophotonics. | 2016 Aug; | 26791097 | |
| Chromosome engineering in zygotes with CRISPR/Cas9. | Boroviak, Katharina; Doe, Brendan; Banerjee, Ruby; Yang, Fengtang; Bradley, Allan | Genesis (New York, N.Y. : 2000). | 2016 Feb; | 26742453 | |
| Yap and Taz play a crucial role in neural crest-derived craniofacial development. | Wang, Jun; Xiao, Yang; Hsu, Chih-Wei; Martinez-Traverso, Idaliz M; Zhang, Min; Bai, Yan; Ishii, Mamoru; Maxson, Robert E; Olson, Eric N; Dickinson, Mary E; Wythe, Joshua D; Martin, James F | Development (Cambridge, England). | 2016 Feb 1; | 26718006 | |
| Precision medicine: an opportunity for a paradigm shift in veterinary medicine. | Lloyd, K C Kent; Khanna, Chand; Hendricks, William; Trent, Jeffrey; Kotlikoff, Michael | Journal of the American Veterinary Medical Association | 2016 Jan 1 | 26684088 | |
| JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. | Berg, Jamee M; Lee, Changhoon; Chen, Leslie; Galvan, Laurie; Cepeda, Carlos; Chen, Jane Y; Peñagarikano, Olga; Stein, Jason L; Li, Alvin; Oguro-Ando, Asami; Miller, Jeremy A; Vashisht, Ajay A; Starks, Mary E; Kite, Elyse P; Tam, Eric; Gdalyahu, Amos; Al-S | Neuron. | 2015 Dec 16; | 1173-91 | 26627310 |
| Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency. | Bone, William P; Washington, Nicole L; Buske, Orion J; Adams, David R; Davis, Joie; Draper, David; Flynn, Elise D; Girdea, Marta; Godfrey, Rena; Golas, Gretchen; Groden, Catherine; Jacobsen, Julius; Köhler, Sebastian; Lee, Elizabeth M J; Links, Amanda E; Markello, Thomas C; Mungall, Christopher J; Nehrebecky, Michele; Robinson, Peter N; Sincan, Murat; Soldatos, Ariane G; Tifft, Cynthia J; Toro, Camilo; Trang, Heather; Valkanas, Elise; Vasilevsky, Nicole; Wahl, Colleen; Wolfe, Lynne A; Boerkoel, Cornelius F; Brudno, Michael; Haendel, Melissa A; Gahl, William A; Smedley, Damian | Genetics in medicine : official journal of the American College of Medical Genetics. | 2016 Jun; | 26562225 | |
| Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models. | Sundberg, John P; Dadras, Soheil S; Silva, Kathleen A; Kennedy, Victoria E; Murray, Stephen A; Denegre, James M; Schofield, Paul N; King Jr, Lloyd E; Wiles, Michael V; Pratt, C Herbert | The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research. | 2015 Nov; | 27-9 | 26551941 |
| Scaling up phenotyping studies. | Svenson, Karen L | Nature biotechnology. | 2015 Nov; | 1150-1 | 26544146 |
| 4D atlas of the mouse embryo for precise morphological staging. | Wong, Michael D; van Eede, Matthijs C; Spring, Shoshana; Jevtic, Stefan; Boughner, Julia C; Lerch, Jason P; Henkelman, R Mark | Development (Cambridge, England). | 2015 Oct 15; | 3583-91 | 26487781 |
| Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5 MHz optical coherence tomography. | Wang, Shang; Singh, Manmohan; Lopez 3rd, Andrew L; Wu, Chen; Raghunathan, Raksha; Schill, Alexander; Li, Jiasong; Larin, Kirill V; Larina, Irina V | Optics letters. | 2015 Oct 15; | 4791-4 | 26469621 |
| Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration. | Zhao, Lihong; Spassieva, Stefka; Gable, Kenneth; Gupta, Sita D; Shi, Lan-Ying; Wang, Jieping; Bielawski, Jacek; Hicks, Wanda L; Krebs, Mark P; Naggert, Juergen; Hannun, Yusuf A; Dunn, Teresa M; Nishina, Patsy M | Proceedings of the National Academy of Sciences of the United States of America. | 2015 Oct 20; | 12962-7 | 26438849 |
| MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. | Guimier, Anne; Gabriel, George C; Bajolle, Fanny; Tsang, Michael; Liu, Hui; Noll, Aaron; Schwartz, Molly; El Malti, Rajae; Smith, Laurie D; Klena, Nikolai T; Jimenez, Gina; Miller, Neil A; Oufadem, Myriam; Moreau de Bellaing, Anne; Yagi, Hisato; Saunders, Carol J; Baker, Candice N; Di Filippo, Sylvie; Peterson, Kevin A; Thiffault, Isabelle; Bole-Feysot, Christine; Cooley, Linda D; Farrow, Emily G; Masson, Cécile; Schoen, Patric; Deleuze, Jean-François; Nitschké, Patrick; Lyonnet, Stanislas; de Pontual, Loic; Murray, Stephen A; Bonnet, Damien; Kingsmore, Stephen F; Amiel, Jeanne; Bouvagnet, Patrice; Lo, Cecilia W; Gordon, Christopher T | Nature genetics. | 2015 Nov; | 26437028 | |
| Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance. | Hugill, Alison J; Stewart, Michelle E; Yon, Marianne A; Probert, Fay; Cox, I Jane; Hough, Tertius A; Scudamore, Cheryl L; Bentley, Liz; Wall, Gary; Wells, Sara E; Cox, Roger D | Biology open. | 2015 Oct 02; | 26432886 | |
| The digital revolution in phenotyping. | Oellrich, Anika; Collier, Nigel; Groza, Tudor; Rebholz-Schuhmann, Dietrich; Shah, Nigam; Bodenreider, Olivier; Boland, Mary Regina; Georgiev, Ivo; Liu, Hongfang; Livingston, Kevin; Luna, Augustin; Mallon, Ann-Marie; Manda, Prashanti; Robinson, Peter N; Rustici, Gabriella; Simon, Michelle; Wang, Liqin; Winnenburg, Rainer; Dumontier, Michel | Briefings in bioinformatics. | 2016 09; | 26420780 | |
| A gene expression resource generated by genome-wide lacZ profiling in the mouse. | Tuck, Elizabeth; Estabel, Jeanne; Oellrich, Anika; Maguire, Anna Karin; Adissu, Hibret A; Souter, Luke; Siragher, Emma; Lillistone, Charlotte; Green, Angela L; Wardle-Jones, Hannah; Carragher, Damian M; Karp, Natasha A; Smedley, Damian; Adams, Niels C; Sa | Disease models & mechanisms. | 2015 Nov; | 1467-78 | 26398943 |
| Live four-dimensional optical coherence tomography reveals embryonic cardiac phenotype in mouse mutant. | Lopez 3rd, Andrew L; Wang, Shang; Larin, Kirill V; Overbeek, Paul A; Larina, Irina V | Journal of biomedical optics. | 2015; | 90501 | 26385422 |
| Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics. | Anderson, Gregory A; Udan, Ryan S; Dickinson, Mary E; Henkelman, R Mark | PloS one. | 2015; | e0137175 | 26340748 |
| A mouse informatics platform for phenotypic and translational discovery. | Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, Mi | Mammalian genome : official journal of the International Mammalian Genome Society. | 2015 Oct; | 413-21 | 26314589 |
| In vivo micro-scale tomography of ciliary behavior in the mammalian oviduct. | Wang, Shang; Burton, Jason C; Behringer, Richard R; Larina, Irina V | Scientific reports. | 2015; | 13216 | 26279472 |
| Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation. | Kirov, Julia V; Adkisson, Michael; Nava, A J; Cipollone, Andreana; Willis, Brandon; Engelhard, Eric K; Lloyd, K C Kent; de Jong, Pieter; West, David B | PloS one. | 2015; | e0134155 | 26275310 |
| Comparative visualization of genotype-phenotype relationships. | Yaikhom, Gagarine; Morgan, Hugh; Sneddon, Duncan; Retha, Ahmad; Atienza-Herrero, Julian; Blake, Andrew; Brown, James; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Ring, Natalie; Santos, Luis; Westerberg, Henrik; Brown, Steve D M; Mallon, Ann-Marie | Nature methods. | 2015 Aug; | 698-9 | 26226357 |
| Principles and application of LIMS in mouse clinics. | Maier, Holger; Schütt, Christine; Steinkamp, Ralph; Hurt, Anja; Schneltzer, Elida; Gormanns, Philipp; Lengger, Christoph; Griffiths, Mark; Melvin, David; Agrawal, Neha; Alcantara, Rafael; Evans, Arthur; Gannon, David; Holroyd, Simon; Kipp, Christian; Raj, | Mammalian genome : official journal of the International Mammalian Genome Society. | 2015 Oct; | 467-81 | 26208973 |
| Precision medicine: Look to the mice. | Lloyd, K C Kent; Meehan, Terry; Beaudet, Arthur; Murray, Steve; Svenson, Karen; McKerlie, Colin; West, David; Morse, Iva; Parkinson, Helen; Brown, Steve; Mallon, Ann-Marie; Moore, Mark | Science (New York, N.Y.). | 2015 Jul 24; | 390 | 26206923 |
| High-resolution three-dimensional in vivo imaging of mouse oviduct using optical coherence tomography. | Burton, Jason C; Wang, Shang; Stewart, C Allison; Behringer, Richard R; Larina, Irina V | Biomedical optics express. | 2015 Jul 1; | 2713-23 | 26203393 |
| PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data. | Kurbatova, Natalja; Mason, Jeremy C; Morgan, Hugh; Meehan, Terrence F; Karp, Natasha A | PloS one. | 2015; | e0131274 | 26147094 |
| Analysis of the effects of curvature and thickness on elastic wave velocity in cornea-like structures by finite element modeling and optical coherence elastography. | Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Aglyamov, Salavat R; Wu, Chen; Liu, Chih-Hao; Larin, Kirill V | Applied physics letters. | 2015 Jun 08; | 26130825 | |
| Disease insights through cross-species phenotype comparisons. | Haendel, Melissa A; Vasilevsky, Nicole; Brush, Matthew; Hochheiser, Harry S; Jacobsen, Julius; Oellrich, Anika; Mungall, Christopher J; Washington, Nicole; Köhler, Sebastian; Lewis, Suzanna E; Robinson, Peter N; Smedley, Damian | Mammalian genome : official journal of the International Mammalian Genome Society. | 2015 Oct; | 26092691 | |
| Reproducibility: use mouse biobanks or lose them. | Lloyd, Kent; Franklin, Craig; Lutz, Cat; Magnuson, Terry | Nature. | 2015 Jun 11; | 151-3 | 26062496 |
| Phase-sensitive optical coherence elastography at 1.5 million A-Lines per second. | Singh, Manmohan; Wu, Chen; Liu, Chih-Hao; Li, Jiasong; Schill, Alexander; Nair, Achuth; Larin, Kirill V | Optics letters. | 2015 Jun 1; | 2588-91 | 26030564 |
| Applying the ARRIVE Guidelines to an In Vivo Database. | Karp, Natasha A; Meehan, Terry F; Morgan, Hugh; Mason, Jeremy C; Blake, Andrew; Kurbatova, Natalja; Smedley, Damian; Jacobsen, Julius; Mott, Richard F; Iyer, Vivek; Matthews, Peter; Melvin, David G; Wells, Sara; Flenniken, Ann M; Masuya, Hiroshi; Wakana, Shigeharu; White, Jacqueline K; Lloyd, K C Kent; Reynolds, Corey L; Paylor, Richard; West, David B; Svenson, Karen L; Chesler, Elissa J; de Angelis, Martin Hrab?; Tocchini-Valentini, Glauco P; Sorg, Tania; Herault, Yann; Parkinson, Helen; Mallon, Ann-Marie; Brown, Steve D M | PLoS biology. | 2015 May; | e1002151 | 25992600 |
| CRISPR-Cas9-mediated genome editing and guide RNA design. | Wiles, Michael V; Qin, Wenning; Cheng, Albert W; Wang, Haoyi | Mammalian genome : official journal of the International Mammalian Genome Society. | 2015 Oct; | 501-10 | 25991564 |
| WGE: a CRISPR database for genome engineering. | Hodgkins, Alex; Farne, Anna; Perera, Sajith; Grego, Tiago; Parry-Smith, David J; Skarnes, William C; Iyer, Vivek | Bioinformatics (Oxford, England). | 2015 Sep 15; | 3078-80 | 25979474 |
| Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice. | Morikawa, Yuka; Zhang, Min; Heallen, Todd; Leach, John; Tao, Ge; Xiao, Yang; Bai, Yan; Li, Wei; Willerson, James T; Martin, James F | Science signaling. | 2015 May 5; | ra41 | 25943351 |
| Linking gene expression to phenotypes via pathway information. | Papatheodorou, Irene; Oellrich, Anika; Smedley, Damian | Journal of biomedical semantics. | 2015; | 25901272 | |
| Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study. | Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Wu, Chen; Liu, Chih-hao; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Sudheendran, Narendran; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill V | Physics in medicine and biology. | 2015 May 7; | 3531-47 | 25860076 |
| Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening. | Gurumurthy, Channabasavaiah B; Joshi, Poonam S; Kurz, Scott G; Ohtsuka, Masato; Quadros, Rolen M; Harms, Donald W; Lloyd, K C Kent | International journal of genomics. | 2015; | 25815306 | |
| Automatic concept recognition using the human phenotype ontology reference and test suite corpora. | Groza, Tudor; Köhler, Sebastian; Doelken, Sandra; Collier, Nigel; Oellrich, Anika; Smedley, Damian; Couto, Francisco M; Baynam, Gareth; Zankl, Andreas; Robinson, Peter N | Database : the journal of biological databases and curation. | 2015; | 25725061 | |
| Algorithms for improved 3-D reconstruction of live mammalian embryo vasculature from optical coherence tomography data. | Kulkarni, Prathamesh M; Rey-Villamizar, Nicolas; Merouane, Amine; Sudheendran, Narendran; Wang, Shang; Garcia, Monica; Larina, Irina V; Roysam, Badrinath; Larin, Kirill V | Quantitative imaging in medicine and surgery. | 2015 Feb; | 25694962 | |
| Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh-Lamb equation. | Han, Zhaolong; Aglyamov, Salavat R; Li, Jiasong; Singh, Manmohan; Wang, Shang; Vantipalli, Srilatha; Wu, Chen; Liu, Chih-Hao; Twa, Michael D; Larin, Kirill V | Journal of biomedical optics. | 2015 Feb; | 20501 | 25649624 |
| Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds. | Yang, Jie; Wang, Shih-Kai; Choi, Murim; Reid, Bryan M; Hu, Yuanyuan; Lee, Yuan-Ling; Herzog, Curtis R; Kim-Berman, Hera; Lee, Moses; Benke, Paul J; Lloyd, K C Kent; Simmer, James P; Hu, Jan C-C | Molecular genetics & genomic medicine. | 2015 Jan; | 40-58 | 25629078 |
| Generation of silver standard concept annotations from biomedical texts with special relevance to phenotypes. | Oellrich, Anika; Collier, Nigel; Smedley, Damian; Groza, Tudor | PloS one. | 2015; | e0116040 | 25607983 |
| A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines. | West, David B; Pasumarthi, Ravi K; Baridon, Brian; Djan, Esi; Trainor, Amanda; Griffey, Stephen M; Engelhard, Eric K; Rapp, Jared; Li, Bowen; de Jong, Pieter J; Lloyd, K C Kent | Genome research. | 2015 Apr; | 598-607 | 25591789 |
| Optical coherence tomography guided microinjections in live mouse embryos: high-resolution targeted manipulation for mouse embryonic research. | Syed, Saba H; Coughlin, Andrew J; Garcia, Monica D; Wang, Shang; West, Jennifer L; Larin, Kirill V; Larina, Irina V | Journal of biomedical optics. | 2015 May; | 25581495 | |
| A common control group - optimising the experiment design to maximise sensitivity. | Bate, Simon; Karp, Natasha A | PloS one. | 2014; | e114872 | 25504147 |
| Noncontact depth-resolved micro-scale optical coherence elastography of the cornea. | Wang, Shang; Larin, Kirill V | Biomedical optics express. | 2014 Nov 01; | 25426312 | |
| Optical coherence elastography for tissue characterization: a review. | Wang, Shang; Larin, Kirill V | Journal of biophotonics. | 2015 Apr; | 279-302 | 25412100 |
| Differentiating untreated and cross-linked porcine corneas of the same measured stiffness with optical coherence elastography. | Li, Jiasong; Han, Zhaolong; Singh, Manmohan; Twa, Michael D; Larin, Kirill V | Journal of biomedical optics. | 2014 Nov; | 25408955 | |
| Impact of temporal variation on design and analysis of mouse knockout phenotyping studies. | Karp, Natasha A; Speak, Anneliese O; White, Jacqueline K; Adams, David J; Hrabe de Angelis, Martin; Herault, Yann; Mott, Richard F | PloS one. | 2014; | e111239 | 25343444 |
| Right Ventricular Epicardial Fibrosis in Mice With Sternal Segment Dislocation. | Adissu, H A; Medhanie, G A; Morikawa, L; White, J K; Newbigging, S; McKerlie, C | Veterinary pathology. | 2014 Oct 3; | 25281652 | |
| A lymphatic defect causes ocular hypertension and glaucoma in mice. | Thomson, Benjamin R; Heinen, Stefan; Jeansson, Marie; Ghosh, Asish K; Fatima, Anees; Sung, Hoon-Ki; Onay, Tuncer; Chen, Hui; Yamaguchi, Shinji; Economides, Aris N; Flenniken, Ann; Gale, Nicholas W; Hong, Young-Kwon; Fawzi, Amani; Liu, Xiaorong; Kume, Tsut | The Journal of clinical investigation. | 2014 Oct; | 4320-4 | 25202984 |
| Vascular development and hemodynamic force in the mouse yolk sac. | Garcia, Monica D; Larina, Irina V | Frontiers in physiology. | 2014; | 308 | 25191274 |
| Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice. | Lee, Angus Yiu-Fai; Lloyd, Kevin C Kent | FEBS open bio. | 2014; | 637-42 | 25161872 |
| Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia. | Salsbury, Grace; Cambridge, Emma L; McIntyre, Zoe; Arends, Mark J; Karp, Natasha A; Isherwood, Christopher; Shannon, Carl; Hooks, Yvette; Sanger Mouse Genetics Project; Ramirez-Solis, Ramiro; Adams, David J; White, Jacqueline K; Speak, Anneliese O | Experimental hematology. | 2014 Dec; | 1053-8.e1 | 25127743 |
| Rescue of germline transmission from chimeras by IVF after sperm analysis. | Li, Ming-Wen; Willis, Brandon J; Evans, Kristin D; Araiza, Renee S; Lee, Angus Yiu-Fai; Lloyd, K C Kent | Transgenic research. | 2015 Feb; | 99-108 | 25080098 |
| Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. | Hopkins, Jessica; Hwang, Grace; Jacob, Justin; Sapp, Nicklas; Bedigian, Rick; Oka, Kazuhiro; Overbeek, Paul; Murray, Steve; Jordan, Philip W | PLoS genetics. | 2014 Jul; | e1004413 | 24992337 |
| Using association rule mining to determine promising secondary phenotyping hypotheses. | Oellrich, Anika; Jacobsen, Julius; Papatheodorou, Irene; Sanger Mouse Genetics Project; Smedley, Damian | Bioinformatics (Oxford, England) | 2014 Jun 15 | i52-59 | 24932005 |
| IVF recovery of mutant mouse lines using sperm cryopreserved with mtg in cryovials. | Li, Ming-Wen; Vallelunga, Jadine M; Kinchen, Kristy L; Rink, Karina L; Zarrabi, Jasmin; Shamamian, Armen O; Lloyd, K C Kent | Cryo letters | 2014 Mar-Apr | 145-53 | 24869647 |
| Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT. | Wong, Michael D; Maezawa, Yoshiro; Lerch, Jason P; Henkelman, R Mark | Development (Cambridge, England) | 2014 Jun | 2533-41 | 24850858 |
| Animal models: Mouse already being charted gene by gene. | Brown, Steve | Nature. | 2014 Apr 17; | 24740057 | |
| Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. | Adissu, Hibret A; Estabel, Jeanne; Sunter, David; Tuck, Elizabeth; Hooks, Yvette; Carragher, Damian M; Clarke, Kay; Karp, Natasha A; Sanger Mouse Genetics Project; Newbigging, Susan; Jones, Nora; Morikawa, Lily; White, Jacqueline K; McKerlie, Colin | Disease models & mechanisms | 2014 May | 515-24 | 24652767 |
| Linking tissues to phenotypes using gene expression profiles. | Oellrich, Anika; Sanger Mouse Genetics Project; Smedley, Damian | Database : the journal of biological databases and curation | 2014 | bau017 | 24634472 |
| Special section guest editorial: Optical coherence tomography and interferometry: advanced engineering and biomedical applications. | Larin, Kirill V; Tuchin, Valery V; Vitkin, Alex | Journal of biomedical optics | 2014 | 21101 | 24570205 |
| Structural stabilization of tissue for embryo phenotyping using micro-CT with iodine staining. | Wong, Michael D; Spring, Shoshana; Henkelman, R Mark | PloS one. | 2013; | 24386367 | |
| Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides. | Takeo, Toru; Fukumoto, Kiyoko; Kondo, Tomoko; Haruguchi, Yukie; Takeshita, Yumi; Nakamuta, Yuko; Tsuchiyama, Shuuji; Yoshimoto, Hidetaka; Shimizu, Norihiko; Li, Ming-Wen; Kinchen, Kristy; Vallelunga, Jadine; Lloyd, K C Kent; Nakagata, Naomi | Cryobiology | 2014 Feb | 7-Dec | 24201107 |
| Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase. | Ryder, Edward; Doe, Brendan; Gleeson, Diane; Houghton, Richard; Dalvi, Priya; Grau, Evelyn; Habib, Bishoy; Miklejewska, Evelina; Newman, Stuart; Sethi, Debarati; Sinclair, Caroline; Vyas, Sapna; Wardle-Jones, Hannah; Sanger Mouse Genetics Project; Bottoml | Transgenic research | 2014 Feb | 177-85 | 24197666 |
| The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. | Koscielny, Gautier; Yaikhom, Gagarine; Iyer, Vivek; Meehan, Terrence F; Morgan, Hugh; Atienza-Herrero, Julian; Blake, Andrew; Chen, Chao-Kung; Easty, Richard; Di Fenza, Armida; Fiegel, Tanja; Grifiths, Mark; Horne, Alan; Karp, Natasha A; Kurbatova, Natalj | Nucleic acids research | 2014 Jan | D802-9 | 24194600 |
| Sestrin-2, a repressor of PDGFR* signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD. | Heidler, Juliana; Fysikopoulos, Athanasios; Wempe, Frank; Seimetz, Michael; Bangsow, Thorsten; Tomasovic, Ana; Veit, Florian; Scheibe, Susan; Pichl, Alexandra; Weisel, Friederike; Lloyd, K C Kent; Jaksch, Peter; Klepetko, Walter; Weissmann, Norbert; von M | Disease models & mechanisms | 2013 Nov | 1378-87 | 24046361 |
| A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). | Carofino, Brandi L; Ayanga, Bernard; Justice, Monica J | Disease models & mechanisms | 2013 Nov | 1494-506 | 24046360 |
| The mouse pathology ontology, MPATH; structure and applications. | Schofield, Paul N; Sundberg, John P; Sundberg, Beth A; McKerlie, Colin; Gkoutos, Georgios V | Journal of biomedical semantics | 2013 | 18 | 24033988 |
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| Combining sperm plug genotyping and coat color chimerism predicts germline transmission. | Lee, Angus Yiu-Fai; Evans, Kristin; Willis, Brandon; Lloyd, K C Kent | Transgenic research | 2013 Jul 17 | NULL | 23860911 |
| The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells. | Taft, Robert A; Low, Benjamin E; Byers, Shannon L; Murray, Stephen A; Kutny, Peter; Wiles, Michael V | PloS one. | 2013; | 23844102 | |
| Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. | Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, David | Disease models & mechanisms | 2013 Jul-Aug | 1049 | 23828646 |
| Mapping registration sensitivity in MR mouse brain images. | van Eede, Matthijs C; Scholz, Jan; Chakravarty, M Mallar; Henkelman, R Mark; Lerch, Jason P | NeuroImage. | 2013 Nov 15; | 23756204 | |
| Effect of different cryoprotectant agents on spermatogenesis efficiency in cryopreserved and grafted neonatal mouse testicular tissue. | Yildiz, Cengiz; Mullen, Brendan; Jarvi, Keith; McKerlie, Colin; Lo, Kirk C | Cryobiology | 2013 Aug | 70-5 | 23721968 |
| Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. | Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, David | Disease models & mechanisms | 2013 May | 571-9 | 23519032 |
| 3D imaging, registration, and analysis of the early mouse embryonic vasculature. | Anderson, Gregory A; Wong, Michael D; Yang, Jian; Henkelman, R Mark | Developmental dynamics : an official publication of the American Association of Anatomists. | 2013 May; | 23417982 | |
| High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos. | Mochida, Keiji; Hasegawa, Ayumi; Li, Ming-Wen; Fray, Martin D; Kito, Seiji; Vallelunga, Jadine M; Lloyd, K C Kent; Yoshiki, Atsushi; Obata, Yuichi; Ogura, Atsuo | PloS one. | 2013; | 23341870 | |
| Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strains. | Li, Ming-Wen; Kinchen, Kristy L; Vallelunga, Jadine M; Young, Diana L; Wright, Kaleb D K; Gorano, Lisa N; Wasson, Katherine; Lloyd, K C Kent | Reproduction (Cambridge, England) | 2013 Mar | 245-54 | 23315689 |
| Robust and sensitive analysis of mouse knockout phenotypes. | Karp, Natasha A; Melvin, David; Sanger Mouse Genetics Project; Mott, Richard F | PloS one | 2012 | e52410 | 23300663 |
| Accessing and mining data from large-scale mouse phenotyping projects. | Morgan, Hugh; Simon, Michelle; Mallon, Ann-Marie | International review of neurobiology | 2012 | 47-70 | 23195311 |
| Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development. | Jiang, Zhengxin; Zhu, Lirong; Hu, Lingyun; Slesnick, Timothy C; Pautler, Robia G; Justice, Monica J; Belmont, John W | Human molecular genetics | 2013 Mar 1 | 879-89 | 23184148 |
| Preclinical research in Rett syndrome: setting the foundation for translational success. | Katz, David M; Berger-Sweeney, Joanne E; Eubanks, James H; Justice, Monica J; Neul, Jeffrey L; Pozzo-Miller, Lucas; Blue, Mary E; Christian, Diana; Crawley, Jacqueline N; Giustetto, Maurizio; Guy, Jacky; Howell, C James; Kron, Miriam; Nelson, Sacha B; Samaco, Rodney C; Schaevitz, Laura R; St Hillaire-Clarke, Coryse; Young, Juan L; Zoghbi, Huda Y; Mamounas, Laura A | Disease models & mechanisms | 2012 Nov | 733-45 | 23115203 |
| Structural and functional concepts in current mouse phenotyping and archiving facilities. | Kollmus, Heike; Post, Rainer; Brielmeier, Markus; Fernandez, Julia; Fuchs, Helmut; McKerlie, Colin; Montoliu, Lluis; Otaegui, Pedro J; Rebelo, Manuel; Riedesel, Hermann; Ruberte, Jesus; Sedlacek, Radislav; de Angelis, Martin Hrabe; Schughart, Klaus | Journal of the American Association for Laboratory Animal Science : JAALAS | 2012 Jul | 418-35 | 23043807 |
| Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development. | Newbigging, Susan; Zhang, Meng; Saba, Julie D | Gene expression patterns : GEP. | 2013 Jan-Feb; | 21-9 | 23041657 |
| Genetically Engineered Mice by Pronuclear DNA microinjection. | Demayo, Janet L; Wang, Jie; Liang, Dongcai; Zhang, Ruina; Demayo, Francesco J | Current protocols in mouse biology | 2012 Sep 1 | 245-262 | 23024927 |
| Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans. | Mallon AM, Iyer V, Melvin D, Morgan H, Parkinson H, Brown SD, Flicek P, Skarnes WC. | Mamm Genome | 2012 Oct | 641-52 | 22991088 |
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| The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data. | Smith CL, Eppig JT. | Mamm Genome | 2012 Oct | 653-68 | 22961259 |
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| A novel 3D mouse embryo atlas based on micro-CT. | Wong, Michael D; Dorr, Adrienne E; Walls, Johnathon R; Lerch, Jason P; Henkelman, R Mark | Development (Cambridge, England). | 2012 Sep; | 22872090 | |
| Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. | Borowsky, Alexander D; Bandhuvula, Padmavathi; Kumar, Ashok; Yoshinaga, Yuko; Nefedov, Mikhail; Fong, Loren G; Zhang, Meng; Baridon, Brian; Dillard, Lisa; de Jong, Pieter; Young, Stephen G; West, David B; Saba, Julie D | Journal of lipid research | 2012 Sep | 1920-31 | 22781001 |
| Neuroanatomical phenotyping of the mouse brain with three-dimensional autofluorescence imaging. | Gleave, Jacqueline A; Wong, Michael D; Dazai, Jun; Altaf, Maliha; Henkelman, R Mark; Lerch, Jason P; Nieman, Brian J | Physiological genomics. | 2012 Aug 1; | 778-85 | 22718750 |
| The role of sphingosine-1-phosphate transporter Spns2 in immune system function. | Nijnik A, Clare S, Hale C, Chen J, Raisen C, Mottram L, Lucas M, Estabel J, Ryder E, Adissu H; Sanger Mouse Genetics Project, Adams NC, Ramirez-Solis R, White JK, Steel KP, Dougan G, Hancock RE. | J Immunol | 2012 Jul 1 | 102-11 | 22664872 |
| Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype. | Li, Ming-Wen; Baridon, Brian; Trainor, Amanda; Djan, Esi; Koehne, Amanda; Griffey, Stephen M; Biggers, John D; Toner, Mehmet; Lloyd, K C Kent | Reproduction (Cambridge, England). | 2012 Apr; | 449-53 | 22274886 |
| A knockout mouse resource for the biomedical research community. | Lloyd KC. | Ann N Y Acad Sci | 2011 Dec | 24-6 | 22211970 |
| Optical Coherence Tomography for live imaging of mammalian development. | Larina IV, Larin KV, Justice MJ, Dickinson ME. | Curr Opin Genet Dev | 2011 Oct | 579-84 | 21962442 |
| Rederivation of transgenic mice from iPS cells derived from frozen tissue. | Lee, Angus Yiu-Fai; Lloyd, K C Kent | Transgenic research. | 2011 Feb; | 167-75 | 20397045 |