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Knockout Mouse Phenotyping (104)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
High-throughput discovery of novel developmental phenotypes.Dickinson, Mary E; Flenniken, Ann M; Ji, Xiao; Teboul, Lydia; Wong, Michael D; White, Jacqueline K; Meehan, Terrence F; Weninger, Wolfgang J; Westerberg, Henrik; Adissu, Hibret; Baker, Candice N; Bower, Lynette; Brown, James M; Caddle, L Brianna; Chiani, Francesco; Clary, Dave; Cleak, James; Daly, Mark J; Denegre, James M; Doe, Brendan; Dolan, Mary E; Edie, Sarah M; Fuchs, Helmut; Gailus-Durner, Valerie; Galli, Antonella; Gambadoro, Alessia; Gallegos, Juan; Guo, Shiying; Horner, Neil R; Hsu, Chih-Wei; Johnson, Sara J; Kalaga, Sowmya; Keith, Lance C; Lanoue, Louise; Lawson, Thomas N; Lek, Monkol; Mark, Manuel; Marschall, Susan; Mason, Jeremy; McElwee, Melissa L; Newbigging, Susan; Nutter, Lauryl M J; Peterson, Kevin A; Ramirez-Solis, Ramiro; Rowland, Douglas J; Ryder, Edward; Samocha, Kaitlin E; Seavitt, John R; Selloum, Mohammed; Szoke-Kovacs, Zsombor; Tamura, Masaru; Trainor, Amanda G; Tudose, Ilinca; Wakana, Shigeharu; Warren, Jonathan; Wendling, Olivia; West, David B; Wong, Leeyean; Yoshiki, Atsushi; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center; MacArthur, Daniel G; Tocchini-Valentini, Glauco P; Gao, Xiang; Flicek, Paul; Bradley, Allan; Skarnes, William C; Justice, Monica J; Parkinson, Helen E; Moore, Mark; Wells, Sara; Braun, Robert E; Svenson, Karen L; de Angelis, Martin Hrabe; Herault, Yann; Mohun, Tim; Mallon, Ann-Marie; Henkelman, R Mark; Brown, Steve D M; Adams, David J; Lloyd, K C Kent; McKerlie, Colin; Beaudet, Arthur L; Bu?an, Maja; Murray, Stephen ANature.2016 Sep 14;27626380
Noncontact Elastic Wave Imaging Optical Coherence Elastography for Evaluating Changes in Corneal Elasticity Due to Crosslinking.Singh, Manmohan; Li, Jiasong; Vantipalli, Srilatha; Wang, Shang; Han, Zhaolong; Nair, Achuth; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill VIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society.2016 May-Jun;27547022
Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.Codner, Gemma F; Lindner, Loic; Caulder, Adam; Wattenhofer-Donzé, Marie; Radage, Adam; Mertz, Annelyse; Eisenmann, Benjamin; Mianné, Joffrey; Evans, Edward P; Beechey, Colin V; Fray, Martin D; Birling, Marie-Christine; Hérault, Yann; Pavlovic, Guillaume; Teboul, LydiaBMC cell biology.2016 Aug 05;27496052
Cryorecovery of Mouse Sperm by Different IVF Methods Using MBCD and GSH.Li, Ming-Wen; Glass, Olivia C; Zarrabi, Jasmin; Baker, Lisa N; Lloyd, K C KentJournal of fertilization in vitro.2016 May;27413624
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.Haeussler, Maximilian; Schönig, Kai; Eckert, Hélène; Eschstruth, Alexis; Mianné, Joffrey; Renaud, Jean-Baptiste; Schneider-Maunoury, Sylvie; Shkumatava, Alena; Teboul, Lydia; Kent, Jim; Joly, Jean-Stephane; Concordet, Jean-PaulGenome biology.2016 Jul 05;27380939
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.Tao, Ge; Kahr, Peter C; Morikawa, Yuka; Zhang, Min; Rahmani, Mahdis; Heallen, Todd R; Li, Lele; Sun, Zhao; Olson, Eric N; Amendt, Brad A; Martin, James FNature.2016 Jun 2;27251288
Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy.Madeo, Marianna; Stewart, Michelle; Sun, Yuyang; Sahir, Nadia; Wiethoff, Sarah; Chandrasekar, Indra; Yarrow, Anna; Rosenfeld, Jill A; Yang, Yaping; Cordeiro, Dawn; McCormick, Elizabeth M; Muraresku, Colleen C; Jepperson, Tyler N; McBeth, Lauren J; Seidahmed, Mohammed Zain; El Khashab, Heba Y; Hamad, Muddathir; Azzedine, Hamid; Clark, Karl; Corrochano, Silvia; Wells, Sara; Elting, Mariet W; Weiss, Marjan M; Burn, Sabrina; Myers, Angela; Landsverk, Megan; Crotwell, Patricia L; Waisfisz, Quinten; Wolf, Nicole I; Nolan, Patrick M; Padilla-Lopez, Sergio; Houlden, Henry; Lifton, Richard; Mane, Shrikant; Singh, Brij B; Falk, Marni J; Mercimek-Mahmutoglu, Saadet; Bilguvar, Kaya; Salih, Mustafa A; Acevedo-Arozena, Abraham; Kruer, Michael CAmerican journal of human genetics.2016 Jun 2;27236917
Rapid, noninvasive quantitation of skin disease in systemic sclerosis using optical coherence elastography.Du, Yong; Liu, Chih-Hao; Lei, Ling; Singh, Manmohan; Li, Jiasong; Hicks, M John; Larin, Kirill V; Mohan, ChandraJournal of biomedical optics.2016 Apr 30;27048877
Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice.Shaheen, Ranad; Anazi, Shams; Ben-Omran, Tawfeg; Seidahmed, Mohammed Zain; Caddle, L Brianna; Palmer, Kristina; Ali, Rehab; Alshidi, Tarfa; Hagos, Samya; Goodwin, Leslie; Hashem, Mais; Wakil, Salma M; Abouelhoda, Mohamed; Colak, Dilek; Murray, Stephen A; American journal of human genetics.2016 Apr 7;27018474
Reporting phenotypes in mouse models when considering body size as a potential confounder.Oellrich, Anika; Meehan, Terrence F; Parkinson, Helen; Sarntivijai, Sirarat; White, Jacqueline K; Karp, Natasha AJournal of biomedical semantics201626865945
Rotational imaging optical coherence tomography for full-body mouse embryonic imaging.Wu, Chen; Sudheendran, Narendran; Singh, Manmohan; Larina, Irina V; Dickinson, Mary E; Larin, Kirill VJournal of biomedical optics.2016 Feb;26848543
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression.West, David B; Engelhard, Eric K; Adkisson, Michael; Nava, A J; Kirov, Julia V; Cipollone, Andreanna; Willis, Brandon; Rapp, Jared; de Jong, Pieter J; Lloyd, Kent CPLoS genetics.2016 Feb;e100569126839965
Chromosome engineering in zygotes with CRISPR/Cas9.Boroviak, Katharina; Doe, Brendan; Banerjee, Ruby; Yang, Fengtang; Bradley, AllanGenesis (New York, N.Y. : 2000).2016 Feb;26742453
Yap and Taz play a crucial role in neural crest-derived craniofacial development.Wang, Jun; Xiao, Yang; Hsu, Chih-Wei; Martinez-Traverso, Idaliz M; Zhang, Min; Bai, Yan; Ishii, Mamoru; Maxson, Robert E; Olson, Eric N; Dickinson, Mary E; Wythe, Joshua D; Martin, James FDevelopment (Cambridge, England).2016 Feb 1;26718006
Precision medicine: an opportunity for a paradigm shift in veterinary medicine.Lloyd, K C Kent; Khanna, Chand; Hendricks, William; Trent, Jeffrey; Kotlikoff, MichaelJournal of the American Veterinary Medical Association2016 Jan 126684088
JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.Berg, Jamee M; Lee, Changhoon; Chen, Leslie; Galvan, Laurie; Cepeda, Carlos; Chen, Jane Y; Peñagarikano, Olga; Stein, Jason L; Li, Alvin; Oguro-Ando, Asami; Miller, Jeremy A; Vashisht, Ajay A; Starks, Mary E; Kite, Elyse P; Tam, Eric; Gdalyahu, Amos; Al-SNeuron.2015 Dec 16;1173-9126627310
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency.Bone, William P; Washington, Nicole L; Buske, Orion J; Adams, David R; Davis, Joie; Draper, David; Flynn, Elise D; Girdea, Marta; Godfrey, Rena; Golas, Gretchen; Groden, Catherine; Jacobsen, Julius; Köhler, Sebastian; Lee, Elizabeth M J; Links, Amanda E; Markello, Thomas C; Mungall, Christopher J; Nehrebecky, Michele; Robinson, Peter N; Sincan, Murat; Soldatos, Ariane G; Tifft, Cynthia J; Toro, Camilo; Trang, Heather; Valkanas, Elise; Vasilevsky, Nicole; Wahl, Colleen; Wolfe, Lynne A; Boerkoel, Cornelius F; Brudno, Michael; Haendel, Melissa A; Gahl, William A; Smedley, DamianGenetics in medicine : official journal of the American College of Medical Genetics.2016 Jun;26562225
Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models.Sundberg, John P; Dadras, Soheil S; Silva, Kathleen A; Kennedy, Victoria E; Murray, Stephen A; Denegre, James M; Schofield, Paul N; King Jr, Lloyd E; Wiles, Michael V; Pratt, C HerbertThe journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research.2015 Nov;27-926551941
Scaling up phenotyping studies.Svenson, Karen LNature biotechnology.2015 Nov;1150-126544146
4D atlas of the mouse embryo for precise morphological staging.Wong, Michael D; van Eede, Matthijs C; Spring, Shoshana; Jevtic, Stefan; Boughner, Julia C; Lerch, Jason P; Henkelman, R MarkDevelopment (Cambridge, England).2015 Oct 15;3583-9126487781
Direct four-dimensional structural and functional imaging of cardiovascular dynamics in mouse embryos with 1.5 MHz optical coherence tomography.Wang, Shang; Singh, Manmohan; Lopez 3rd, Andrew L; Wu, Chen; Raghunathan, Raksha; Schill, Alexander; Li, Jiasong; Larin, Kirill V; Larina, Irina VOptics letters.2015 Oct 15;4791-426469621
Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration.Zhao, Lihong; Spassieva, Stefka; Gable, Kenneth; Gupta, Sita D; Shi, Lan-Ying; Wang, Jieping; Bielawski, Jacek; Hicks, Wanda L; Krebs, Mark P; Naggert, Juergen; Hannun, Yusuf A; Dunn, Teresa M; Nishina, Patsy MProceedings of the National Academy of Sciences of the United States of America.2015 Oct 20;12962-726438849
A gene expression resource generated by genome-wide lacZ profiling in the mouse.Tuck, Elizabeth; Estabel, Jeanne; Oellrich, Anika; Maguire, Anna Karin; Adissu, Hibret A; Souter, Luke; Siragher, Emma; Lillistone, Charlotte; Green, Angela L; Wardle-Jones, Hannah; Carragher, Damian M; Karp, Natasha A; Smedley, Damian; Adams, Niels C; SaDisease models & mechanisms.2015 Nov;1467-7826398943
Live four-dimensional optical coherence tomography reveals embryonic cardiac phenotype in mouse mutant.Lopez 3rd, Andrew L; Wang, Shang; Larin, Kirill V; Overbeek, Paul A; Larina, Irina VJournal of biomedical optics.2015;9050126385422
Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics.Anderson, Gregory A; Udan, Ryan S; Dickinson, Mary E; Henkelman, R MarkPloS one.2015;e013717526340748
A mouse informatics platform for phenotypic and translational discovery.Ring, Natalie; Meehan, Terrence F; Blake, Andrew; Brown, James; Chen, Chao-Kung; Conte, Nathalie; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Jacobsen, Julius O B; Karp, Natasha; Lawson, Thomas; Mason, Jeremy C; Matthews, Peter; Morgan, Hugh; Relac, MiMammalian genome : official journal of the International Mammalian Genome Society.2015 Oct;413-2126314589
In vivo micro-scale tomography of ciliary behavior in the mammalian oviduct.Wang, Shang; Burton, Jason C; Behringer, Richard R; Larina, Irina VScientific reports.2015;1321626279472
Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation.Kirov, Julia V; Adkisson, Michael; Nava, A J; Cipollone, Andreana; Willis, Brandon; Engelhard, Eric K; Lloyd, K C Kent; de Jong, Pieter; West, David BPloS one.2015;e013415526275310
Comparative visualization of genotype-phenotype relationships.Yaikhom, Gagarine; Morgan, Hugh; Sneddon, Duncan; Retha, Ahmad; Atienza-Herrero, Julian; Blake, Andrew; Brown, James; Di Fenza, Armida; Fiegel, Tanja; Horner, Neil; Ring, Natalie; Santos, Luis; Westerberg, Henrik; Brown, Steve D M; Mallon, Ann-MarieNature methods.2015 Aug;698-926226357
Principles and application of LIMS in mouse clinics.Maier, Holger; Schütt, Christine; Steinkamp, Ralph; Hurt, Anja; Schneltzer, Elida; Gormanns, Philipp; Lengger, Christoph; Griffiths, Mark; Melvin, David; Agrawal, Neha; Alcantara, Rafael; Evans, Arthur; Gannon, David; Holroyd, Simon; Kipp, Christian; Raj,Mammalian genome : official journal of the International Mammalian Genome Society.2015 Oct;467-8126208973
Precision medicine: Look to the mice.Lloyd, K C Kent; Meehan, Terry; Beaudet, Arthur; Murray, Steve; Svenson, Karen; McKerlie, Colin; West, David; Morse, Iva; Parkinson, Helen; Brown, Steve; Mallon, Ann-Marie; Moore, MarkScience (New York, N.Y.).2015 Jul 24;39026206923
High-resolution three-dimensional in vivo imaging of mouse oviduct using optical coherence tomography.Burton, Jason C; Wang, Shang; Stewart, C Allison; Behringer, Richard R; Larina, Irina VBiomedical optics express.2015 Jul 1;2713-2326203393
PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data.Kurbatova, Natalja; Mason, Jeremy C; Morgan, Hugh; Meehan, Terrence F; Karp, Natasha APloS one.2015;e013127426147094
Reproducibility: use mouse biobanks or lose them.Lloyd, Kent; Franklin, Craig; Lutz, Cat; Magnuson, TerryNature.2015 Jun 11;151-326062496
Phase-sensitive optical coherence elastography at 1.5 million A-Lines per second.Singh, Manmohan; Wu, Chen; Liu, Chih-Hao; Li, Jiasong; Schill, Alexander; Nair, Achuth; Larin, Kirill VOptics letters.2015 Jun 1;2588-9126030564
Applying the ARRIVE Guidelines to an In Vivo Database.Karp, Natasha A; Meehan, Terry F; Morgan, Hugh; Mason, Jeremy C; Blake, Andrew; Kurbatova, Natalja; Smedley, Damian; Jacobsen, Julius; Mott, Richard F; Iyer, Vivek; Matthews, Peter; Melvin, David G; Wells, Sara; Flenniken, Ann M; Masuya, Hiroshi; Wakana, Shigeharu; White, Jacqueline K; Lloyd, K C Kent; Reynolds, Corey L; Paylor, Richard; West, David B; Svenson, Karen L; Chesler, Elissa J; de Angelis, Martin Hrab?; Tocchini-Valentini, Glauco P; Sorg, Tania; Herault, Yann; Parkinson, Helen; Mallon, Ann-Marie; Brown, Steve D MPLoS biology.2015 May;e100215125992600
CRISPR-Cas9-mediated genome editing and guide RNA design.Wiles, Michael V; Qin, Wenning; Cheng, Albert W; Wang, HaoyiMammalian genome : official journal of the International Mammalian Genome Society.2015 Oct;501-1025991564
WGE: a CRISPR database for genome engineering.Hodgkins, Alex; Farne, Anna; Perera, Sajith; Grego, Tiago; Parry-Smith, David J; Skarnes, William C; Iyer, VivekBioinformatics (Oxford, England).2015 Sep 15;3078-8025979474
Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice.Morikawa, Yuka; Zhang, Min; Heallen, Todd; Leach, John; Tao, Ge; Xiao, Yang; Bai, Yan; Li, Wei; Willerson, James T; Martin, James FScience signaling.2015 May 5;ra4125943351
Linking gene expression to phenotypes via pathway information.Papatheodorou, Irene; Oellrich, Anika; Smedley, DamianJournal of biomedical semantics.2015;25901272
Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study.Han, Zhaolong; Li, Jiasong; Singh, Manmohan; Wu, Chen; Liu, Chih-hao; Wang, Shang; Idugboe, Rita; Raghunathan, Raksha; Sudheendran, Narendran; Aglyamov, Salavat R; Twa, Michael D; Larin, Kirill VPhysics in medicine and biology.2015 May 7;3531-4725860076
Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening.Gurumurthy, Channabasavaiah B; Joshi, Poonam S; Kurz, Scott G; Ohtsuka, Masato; Quadros, Rolen M; Harms, Donald W; Lloyd, K C KentInternational journal of genomics.2015;25815306
Automatic concept recognition using the human phenotype ontology reference and test suite corpora.Groza, Tudor; Köhler, Sebastian; Doelken, Sandra; Collier, Nigel; Oellrich, Anika; Smedley, Damian; Couto, Francisco M; Baynam, Gareth; Zankl, Andreas; Robinson, Peter NDatabase : the journal of biological databases and curation.2015;25725061
Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh-Lamb equation.Han, Zhaolong; Aglyamov, Salavat R; Li, Jiasong; Singh, Manmohan; Wang, Shang; Vantipalli, Srilatha; Wu, Chen; Liu, Chih-Hao; Twa, Michael D; Larin, Kirill VJournal of biomedical optics.2015 Feb;2050125649624
Taurodontism, variations in tooth number, and misshapened crowns in Wnt10a null mice and human kindreds.Yang, Jie; Wang, Shih-Kai; Choi, Murim; Reid, Bryan M; Hu, Yuanyuan; Lee, Yuan-Ling; Herzog, Curtis R; Kim-Berman, Hera; Lee, Moses; Benke, Paul J; Lloyd, K C Kent; Simmer, James P; Hu, Jan C-CMolecular genetics & genomic medicine.2015 Jan;40-5825629078
Generation of silver standard concept annotations from biomedical texts with special relevance to phenotypes.Oellrich, Anika; Collier, Nigel; Smedley, Damian; Groza, TudorPloS one.2015;e011604025607983
A lacZ reporter gene expression atlas for 313 adult KOMP mutant mouse lines.West, David B; Pasumarthi, Ravi K; Baridon, Brian; Djan, Esi; Trainor, Amanda; Griffey, Stephen M; Engelhard, Eric K; Rapp, Jared; Li, Bowen; de Jong, Pieter J; Lloyd, K C KentGenome research.2015 Apr;598-60725591789
Optical coherence tomography guided microinjections in live mouse embryos: high-resolution targeted manipulation for mouse embryonic research.Syed, Saba H; Coughlin, Andrew J; Garcia, Monica D; Wang, Shang; West, Jennifer L; Larin, Kirill V; Larina, Irina VJournal of biomedical optics.2015 May;25581495
A common control group - optimising the experiment design to maximise sensitivity.Bate, Simon; Karp, Natasha APloS one.2014;e11487225504147
Optical coherence elastography for tissue characterization: a review.Wang, Shang; Larin, Kirill VJournal of biophotonics.2015 Apr;279-30225412100
Differentiating untreated and cross-linked porcine corneas of the same measured stiffness with optical coherence elastography.Li, Jiasong; Han, Zhaolong; Singh, Manmohan; Twa, Michael D; Larin, Kirill VJournal of biomedical optics.2014 Nov;25408955
Impact of temporal variation on design and analysis of mouse knockout phenotyping studies.Karp, Natasha A; Speak, Anneliese O; White, Jacqueline K; Adams, David J; Hrabe de Angelis, Martin; Herault, Yann; Mott, Richard FPloS one.2014;e11123925343444
Right Ventricular Epicardial Fibrosis in Mice With Sternal Segment Dislocation.Adissu, H A; Medhanie, G A; Morikawa, L; White, J K; Newbigging, S; McKerlie, CVeterinary pathology.2014 Oct 3;25281652
A lymphatic defect causes ocular hypertension and glaucoma in mice.Thomson, Benjamin R; Heinen, Stefan; Jeansson, Marie; Ghosh, Asish K; Fatima, Anees; Sung, Hoon-Ki; Onay, Tuncer; Chen, Hui; Yamaguchi, Shinji; Economides, Aris N; Flenniken, Ann; Gale, Nicholas W; Hong, Young-Kwon; Fawzi, Amani; Liu, Xiaorong; Kume, TsutThe Journal of clinical investigation.2014 Oct;4320-425202984
Vascular development and hemodynamic force in the mouse yolk sac.Garcia, Monica D; Larina, Irina VFrontiers in physiology.2014;30825191274
Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice.Lee, Angus Yiu-Fai; Lloyd, Kevin C KentFEBS open bio.2014;637-4225161872
Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia.Salsbury, Grace; Cambridge, Emma L; McIntyre, Zoe; Arends, Mark J; Karp, Natasha A; Isherwood, Christopher; Shannon, Carl; Hooks, Yvette; Sanger Mouse Genetics Project; Ramirez-Solis, Ramiro; Adams, David J; White, Jacqueline K; Speak, Anneliese OExperimental hematology.2014 Dec;1053-8.e125127743
Rescue of germline transmission from chimeras by IVF after sperm analysis.Li, Ming-Wen; Willis, Brandon J; Evans, Kristin D; Araiza, Renee S; Lee, Angus Yiu-Fai; Lloyd, K C KentTransgenic research.2015 Feb;99-10825080098
Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes.Hopkins, Jessica; Hwang, Grace; Jacob, Justin; Sapp, Nicklas; Bedigian, Rick; Oka, Kazuhiro; Overbeek, Paul; Murray, Steve; Jordan, Philip WPLoS genetics.2014 Jul;e100441324992337
Using association rule mining to determine promising secondary phenotyping hypotheses.Oellrich, Anika; Jacobsen, Julius; Papatheodorou, Irene; Sanger Mouse Genetics Project; Smedley, DamianBioinformatics (Oxford, England)2014 Jun 15i52-5924932005
IVF recovery of mutant mouse lines using sperm cryopreserved with mtg in cryovials.Li, Ming-Wen; Vallelunga, Jadine M; Kinchen, Kristy L; Rink, Karina L; Zarrabi, Jasmin; Shamamian, Armen O; Lloyd, K C KentCryo letters2014 Mar-Apr145-5324869647
Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT.Wong, Michael D; Maezawa, Yoshiro; Lerch, Jason P; Henkelman, R MarkDevelopment (Cambridge, England)2014 Jun2533-4124850858
Animal models: Mouse already being charted gene by gene.Brown, SteveNature.2014 Apr 17;24740057
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.Adissu, Hibret A; Estabel, Jeanne; Sunter, David; Tuck, Elizabeth; Hooks, Yvette; Carragher, Damian M; Clarke, Kay; Karp, Natasha A; Sanger Mouse Genetics Project; Newbigging, Susan; Jones, Nora; Morikawa, Lily; White, Jacqueline K; McKerlie, ColinDisease models & mechanisms2014 May515-2424652767
Linking tissues to phenotypes using gene expression profiles.Oellrich, Anika; Sanger Mouse Genetics Project; Smedley, DamianDatabase : the journal of biological databases and curation2014bau01724634472
Special section guest editorial: Optical coherence tomography and interferometry: advanced engineering and biomedical applications.Larin, Kirill V; Tuchin, Valery V; Vitkin, AlexJournal of biomedical optics20142110124570205
Structural stabilization of tissue for embryo phenotyping using micro-CT with iodine staining.Wong, Michael D; Spring, Shoshana; Henkelman, R MarkPloS one.2013;24386367
Investigations of motility and fertilization potential in thawed cryopreserved mouse sperm from cold-stored epididymides.Takeo, Toru; Fukumoto, Kiyoko; Kondo, Tomoko; Haruguchi, Yukie; Takeshita, Yumi; Nakamuta, Yuko; Tsuchiyama, Shuuji; Yoshimoto, Hidetaka; Shimizu, Norihiko; Li, Ming-Wen; Kinchen, Kristy; Vallelunga, Jadine; Lloyd, K C Kent; Nakagata, NaomiCryobiology2014 Feb7-Dec24201107
Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase.Ryder, Edward; Doe, Brendan; Gleeson, Diane; Houghton, Richard; Dalvi, Priya; Grau, Evelyn; Habib, Bishoy; Miklejewska, Evelina; Newman, Stuart; Sethi, Debarati; Sinclair, Caroline; Vyas, Sapna; Wardle-Jones, Hannah; Sanger Mouse Genetics Project; BottomlTransgenic research2014 Feb177-8524197666
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.Koscielny, Gautier; Yaikhom, Gagarine; Iyer, Vivek; Meehan, Terrence F; Morgan, Hugh; Atienza-Herrero, Julian; Blake, Andrew; Chen, Chao-Kung; Easty, Richard; Di Fenza, Armida; Fiegel, Tanja; Grifiths, Mark; Horne, Alan; Karp, Natasha A; Kurbatova, NataljNucleic acids research2014 JanD802-924194600
Sestrin-2, a repressor of PDGFR* signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.Heidler, Juliana; Fysikopoulos, Athanasios; Wempe, Frank; Seimetz, Michael; Bangsow, Thorsten; Tomasovic, Ana; Veit, Florian; Scheibe, Susan; Pichl, Alexandra; Weisel, Friederike; Lloyd, K C Kent; Jaksch, Peter; Klepetko, Walter; Weissmann, Norbert; von MDisease models & mechanisms2013 Nov1378-8724046361
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).Carofino, Brandi L; Ayanga, Bernard; Justice, Monica JDisease models & mechanisms2013 Nov1494-50624046360
The mouse pathology ontology, MPATH; structure and applications.Schofield, Paul N; Sundberg, John P; Sundberg, Beth A; McKerlie, Colin; Gkoutos, Georgios VJournal of biomedical semantics20131824033988
Design and implementation of a custom built optical projection tomography system.Wong, Michael D; Dazai, Jun; Walls, Johnathon R; Gale, Nicholas W; Henkelman, R MarkPloS one.2013;24023880
Combining sperm plug genotyping and coat color chimerism predicts germline transmission.Lee, Angus Yiu-Fai; Evans, Kristin; Willis, Brandon; Lloyd, K C KentTransgenic research2013 Jul 17NULL23860911
The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells.Taft, Robert A; Low, Benjamin E; Byers, Shannon L; Murray, Stephen A; Kutny, Peter; Wiles, Michael VPloS one.2013;23844102
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening.Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, DavidDisease models & mechanisms2013 Jul-Aug104923828646
Mapping registration sensitivity in MR mouse brain images.van Eede, Matthijs C; Scholz, Jan; Chakravarty, M Mallar; Henkelman, R Mark; Lerch, Jason PNeuroImage.2013 Nov 15;23756204
Effect of different cryoprotectant agents on spermatogenesis efficiency in cryopreserved and grafted neonatal mouse testicular tissue.Yildiz, Cengiz; Mullen, Brendan; Jarvi, Keith; McKerlie, Colin; Lo, Kirk CCryobiology2013 Aug70-523721968
Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening.Adams, David; Baldock, Richard; Bhattacharya, Shoumo; Copp, Andrew J; Dickinson, Mary; Greene, Nicholas D E; Henkelman, Mark; Justice, Monica; Mohun, Timothy; Murray, Stephen A; Pauws, Erwin; Raess, Michael; Rossant, Janet; Weaver, Tom; West, DavidDisease models & mechanisms2013 May571-923519032
3D imaging, registration, and analysis of the early mouse embryonic vasculature.Anderson, Gregory A; Wong, Michael D; Yang, Jian; Henkelman, R MarkDevelopmental dynamics : an official publication of the American Association of Anatomists.2013 May;23417982
High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos.Mochida, Keiji; Hasegawa, Ayumi; Li, Ming-Wen; Fray, Martin D; Kito, Seiji; Vallelunga, Jadine M; Lloyd, K C Kent; Yoshiki, Atsushi; Obata, Yuichi; Ogura, AtsuoPloS one.2013;23341870
Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strains.Li, Ming-Wen; Kinchen, Kristy L; Vallelunga, Jadine M; Young, Diana L; Wright, Kaleb D K; Gorano, Lisa N; Wasson, Katherine; Lloyd, K C KentReproduction (Cambridge, England)2013 Mar245-5423315689
Robust and sensitive analysis of mouse knockout phenotypes.Karp, Natasha A; Melvin, David; Sanger Mouse Genetics Project; Mott, Richard FPloS one2012e5241023300663
Accessing and mining data from large-scale mouse phenotyping projects.Morgan, Hugh; Simon, Michelle; Mallon, Ann-MarieInternational review of neurobiology201247-7023195311
Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development.Jiang, Zhengxin; Zhu, Lirong; Hu, Lingyun; Slesnick, Timothy C; Pautler, Robia G; Justice, Monica J; Belmont, John WHuman molecular genetics2013 Mar 1879-8923184148
Preclinical research in Rett syndrome: setting the foundation for translational success.Katz, David M; Berger-Sweeney, Joanne E; Eubanks, James H; Justice, Monica J; Neul, Jeffrey L; Pozzo-Miller, Lucas; Blue, Mary E; Christian, Diana; Crawley, Jacqueline N; Giustetto, Maurizio; Guy, Jacky; Howell, C James; Kron, Miriam; Nelson, Sacha B; Samaco, Rodney C; Schaevitz, Laura R; St Hillaire-Clarke, Coryse; Young, Juan L; Zoghbi, Huda Y; Mamounas, Laura ADisease models & mechanisms2012 Nov733-4523115203
Structural and functional concepts in current mouse phenotyping and archiving facilities.Kollmus, Heike; Post, Rainer; Brielmeier, Markus; Fernandez, Julia; Fuchs, Helmut; McKerlie, Colin; Montoliu, Lluis; Otaegui, Pedro J; Rebelo, Manuel; Riedesel, Hermann; Ruberte, Jesus; Sedlacek, Radislav; de Angelis, Martin Hrabe; Schughart, KlausJournal of the American Association for Laboratory Animal Science : JAALAS2012 Jul418-3523043807
Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development.Newbigging, Susan; Zhang, Meng; Saba, Julie DGene expression patterns : GEP.2013 Jan-Feb;21-923041657
Genetically Engineered Mice by Pronuclear DNA microinjection.Demayo, Janet L; Wang, Jie; Liang, Dongcai; Zhang, Ruina; Demayo, Francesco JCurrent protocols in mouse biology2012 Sep 1245-26223024927
Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans.Mallon AM, Iyer V, Melvin D, Morgan H, Parkinson H, Brown SD, Flicek P, Skarnes WC.Mamm Genome2012 Oct641-5222991088
The mammalian gene function resource: the international knockout mouse consortium.Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, et al.Mamm Genome2012 Oct580-622968824
The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data.Smith CL, Eppig JT.Mamm Genome2012 Oct653-6822961259
Centralized mouse repositories.Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Horlein, Andreas; Davisson, Muriel TMammalian genome : official journal of the International Mammalian Genome Society2012 Oct559-7122945696
The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.Brown SD, Moore MW.Mamm Genome2012 Oct632-4022940749
Beyond knockouts: cre resources for conditional mutagenesis.Murray SA, Eppig JT, Smedley D, Simpson EM, Rosenthal N.Mamm Genome2012 Oct587-9922926223
A novel 3D mouse embryo atlas based on micro-CT.Wong, Michael D; Dorr, Adrienne E; Walls, Johnathon R; Lerch, Jason P; Henkelman, R MarkDevelopment (Cambridge, England).2012 Sep;22872090
Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues.Borowsky, Alexander D; Bandhuvula, Padmavathi; Kumar, Ashok; Yoshinaga, Yuko; Nefedov, Mikhail; Fong, Loren G; Zhang, Meng; Baridon, Brian; Dillard, Lisa; de Jong, Pieter; Young, Stephen G; West, David B; Saba, Julie DJournal of lipid research2012 Sep1920-3122781001
Neuroanatomical phenotyping of the mouse brain with three-dimensional autofluorescence imaging.Gleave, Jacqueline A; Wong, Michael D; Dazai, Jun; Altaf, Maliha; Henkelman, R Mark; Lerch, Jason P; Nieman, Brian JPhysiological genomics.2012 Aug 1;778-8522718750
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.Nijnik A, Clare S, Hale C, Chen J, Raisen C, Mottram L, Lucas M, Estabel J, Ryder E, Adissu H; Sanger Mouse Genetics Project, Adams NC, Ramirez-Solis R, White JK, Steel KP, Dougan G, Hancock RE.J Immunol2012 Jul 1102-1122664872
Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype.Li, Ming-Wen; Baridon, Brian; Trainor, Amanda; Djan, Esi; Koehne, Amanda; Griffey, Stephen M; Biggers, John D; Toner, Mehmet; Lloyd, K C KentReproduction (Cambridge, England).2012 Apr;449-5322274886
A knockout mouse resource for the biomedical research community.Lloyd KC.Ann N Y Acad Sci2011 Dec24-622211970
Optical Coherence Tomography for live imaging of mammalian development.Larina IV, Larin KV, Justice MJ, Dickinson ME.Curr Opin Genet Dev2011 Oct579-8421962442
Rederivation of transgenic mice from iPS cells derived from frozen tissue.Lee, Angus Yiu-Fai; Lloyd, K C KentTransgenic research.2011 Feb;167-7520397045


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