NIH Director's Pioneer Award Program

Publications


 
Regulation of immune responses and tolerance: the microRNA perspective.
Chen, Chang-Zheng; Schaffert, Steven; Fragoso, Rita; Loh, Christina
Immunological reviews. 2013 May. 112-28 
PMID: 23550642 [PubMed]
Dynamic regulatory network controlling TH17 cell differentiation.
Yosef, Nir; Shalek, Alex K; Gaublomme, Jellert T; Jin, Hulin; Lee, Youjin; Awasthi, Amit; Wu, Chuan; Karwacz, Katarzyna; Xiao, Sheng; Jorgolli, Marsela; Gennert, David; Satija, Rahul; Shakya, Arvind; Lu, Diana Y; Trombetta, John J; Pillai, Meenu R; Ratcli
Nature. 2013 Apr 25. 461-8 
PMID: 23467089 [PubMed]
Macrophage biology in development, homeostasis and disease.
Wynn, Thomas A; Chawla, Ajay; Pollard, Jeffrey W
Nature. 2013 Apr 25. 445-55 
PMID: 23619691 [PubMed]
Functional inhibition of UQCRB suppresses angiogenesis in zebrafish.
Cho, Yoon Sun; Jung, Hye Jin; Seok, Seung Hyeok; Payumo, Alexander Y; Chen, James K; Kwon, Ho Jeong
Biochemical and biophysical research communications. 2013 Apr 19. 396-400 
PMID: 23454382 [PubMed]
Facile and Stabile Linkages through Tyrosine: Bioconjugation Strategies with the Tyrosine-Click Reaction.
Ban, Hitoshi; Nagano, Masanobu; Gavrilyuk, Julia; Hakamata, Wataru; Inokuma, Tsubasa; Barbas 3rd, Carlos F
Bioconjugate chemistry. 2013 Apr 17. 520-32 
PMID: 23534985 [PubMed]
Inferring evoked brain connectivity through adaptive perturbation.
Lepage, Kyle Q; Ching, ShiNung; Kramer, Mark A
Journal of computational neuroscience. 2013 Apr. 303-18 
PMID: 22990598 [PubMed]
Assessing the effects of pharmacological agents on respiratory dynamics using time-series modeling.
Wong, Kin Foon Kevin; Gong, Jen J; Cotten, Joseph F; Solt, Ken; Brown, Emery N
IEEE transactions on bio-medical engineering. 2013 Apr. 1118-25 
PMID: 23193230 [PubMed]
Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli.
Gat-Viks, Irit; Chevrier, Nicolas; Wilentzik, Roni; Eisenhaure, Thomas; Raychowdhury, Raktima; Steuerman, Yael; Shalek, Alex K; Hacohen, Nir; Amit, Ido; Regev, Aviv
Nature biotechnology. 2013 Apr. 342-9 
PMID: 23503680 [PubMed]
The Fumagillin Biosynthetic Gene Cluster in Aspergillus fumigatus Encodes a Cryptic Terpene Cyclase Involved in the Formation of ýý-trans-Bergamotene.
Lin, Hsiao-Ching; Chooi, Yit-Heng; Dhingra, Sourabh; Xu, Wei; Calvo, Ana M; Tang, Yi
Journal of the American Chemical Society. 2013 Mar 27. 4616-9 
PMID: 23488861 [PubMed]
Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures.
Sun, Hongyu; Kosaras, Bela; Klein, Peter M; Jensen, Frances E
Proceedings of the National Academy of Sciences of the United States of America. 2013 Mar 26. 5199-204 
PMID: 23479645 [PubMed]
Global analysis of phosphorylation networks in humans.
Hu, Jianfei; Rho, Hee-Sool; Newman, Robert H; Hwang, Woochang; Neiswinger, John; Zhu, Heng; Zhang, Jin; Qian, Jiang
Biochimica et biophysica acta. 2013 Mar 21. NULL 
PMID: 23524292 [PubMed]
Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease.
Brewer, Alison C; Mustafi, Soumyajit Banerjee; Murray, Thomas V A; Rajasekaran, Namakkal Soorappan; Benjamin, Ivor J
Antioxidants & redox signaling. 2013 Mar 20. 1114-27 
PMID: 22938199 [PubMed]
Electroencephalogram signatures of loss and recovery of consciousness from propofol.
Purdon, Patrick L; Pierce, Eric T; Mukamel, Eran A; Prerau, Michael J; Walsh, John L; Wong, Kin Foon K; Salazar-Gomez, Andres F; Harrell, Priscilla G; Sampson, Aaron L; Cimenser, Aylin; Ching, ShiNung; Kopell, Nancy J; Tavares-Stoeckel, Casie; Habeeb, Kat
Proceedings of the National Academy of Sciences of the United States of America. 2013 Mar 19. E1142-51 
PMID: 23487781 [PubMed]
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.
Rhee, Hyun-Woo; Zou, Peng; Udeshi, Namrata D; Martell, Jeffrey D; Mootha, Vamsi K; Carr, Steven A; Ting, Alice Y
Science (New York, N.Y.). 2013 Mar 15. 1328-31 
PMID: 23371551 [PubMed]
High-sensitivity ultrasound-modulated optical tomography with a photorefractive polymer.
Suzuki, Yuta; Lai, Puxiang; Xu, Xiao; Wang, Lihong
Optics letters. 2013 Mar 15. 899-901 
PMID: 23503253 [PubMed]
A Major Epigenetic Programming Mechanism Guided by piRNAs.
Huang, Xiao A; Yin, Hang; Sweeney, Sarah; Raha, Debasish; Snyder, Michael; Lin, Haifan
Developmental cell. 2013 Mar 11. 502-16 
PMID: 23434410 [PubMed]
Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1.
Wu, Chuan; Yosef, Nir; Thalhamer, Theresa; Zhu, Chen; Xiao, Sheng; Kishi, Yasuhiro; Regev, Aviv; Kuchroo, Vijay K
Nature. 2013 Mar 6. NULL 
PMID: 23467085 [PubMed]
Early folding events protect aggregation-prone regions of a ýý-rich protein.
Budyak, Ivan L; Krishnan, Beena; Marcelino-Cruz, Anna M; Ferrolino, Mylene C; Zhuravleva, Anastasia; Gierasch, Lila M
Structure (London, England : 1993). 2013 Mar 5. 476-85 
PMID: 23454187 [PubMed]
Investigation of neovascularization in three-dimensional porous scaffolds in vivo by a combination of multiscale photoacoustic microscopy and optical coherence tomography.
Cai, Xin; Zhang, Yu; Li, Li; Choi, Sung-Wook; MacEwan, Matthew R; Yao, Junjie; Kim, Chulhong; Xia, Younan; Wang, Lihong V
Tissue engineering. Part C, Methods. 2013 Mar. 196-204 
PMID: 22838500 [PubMed]
Affective value and associative processing share a cortical substrate.
Shenhav, Amitai; Barrett, Lisa Feldman; Bar, Moshe
Cognitive, affective & behavioral neuroscience. 2013 Mar. 46-59 
PMID: 23090717 [PubMed]
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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892