Full descriptions are available for those projects with a released
Notice of Grant Award.
Nathalie Y.R. Agar, Ph.D.
Brigham and Women’s Hospital / Harvard Medical School
Project Title: Real-Time
Stereotactic Mass Spectrometry Tissue Analysis for Intraoperative
Neurosurgical Guidance
Ritesh Agarwal, Ph.D.
University of Pennsylvania
Project Title: Optoelectronic
Nanowire Probes for Investigation of Intracellular Processes
Rommie E. Amaro, Ph.D.
University of California, Irvine
Project Title: A
Structural Systems Biology Approach to Drug Discovery
Alexei Aravin, Ph.D.
California Institute of Technology
Project Title: Taming
of Small RNA-based Epigenetic Mechanisms
Andrea M. Armani, Ph.D.
University of Southern California
Project Title: Ultrasensitive
Nanolasers for Epigenetics Investigations
Diana M. Bautista, Ph.D.
University of California, Berkeley
Project Title: New
Approaches to Identify Molecular Mechanisms of Touch and Pain in Mammals
Lynette S. Cegelski, Ph.D.
Stanford University
Project Title: Structure,
Function, and Disruption of Microbial Amyloid Assembly and Biofilm Formation
Jianjun Cheng, Ph.D.
University of Illinois at Urbana-Champaign
Project Title: Developing
Clinically Applicable, Cancer-Targeting Polymeric Nanoconjugates
Neil C. Chi, M.D., Ph.D.
University of California, San Diego, School of Medicine
Project Title: Directed
Cardiac Cellular Programming: A New Paradigm for Cardiac Regeneration
Adam Ezra Cohen, Ph.D.
Harvard University
Project Title: Optical
Sensing of Voltage, pH, and Small Molecules Using Microbial Rhodopsins
Chengkai Dai, Ph.D.
The Jackson Laboratory, Maine
Project Title: Role
of a Novel Stress Response Mechanism-Genetic Buffering-in Tumor Evolution
Sandeep Robert Datta, M.D., Ph.D.
Harvard Medical School
Project Title: Revealing
fear: New Methods to Study Neural circuits, Behavior, and Disease
Dino Di Carlo, Ph.D.
University of California, Los Angeles
Project Title: Engineering
the Intracellular Micro- and Nanoenvironment
Alexander R. Dunn, Ph.D.
Stanford University
Project Title: Uncovering
New Roles for Mechanical Force in Tissue Development and Extracellular Matrix
Remodeling
Conor L. Evans, Ph.D.
Massachusetts General Hospital / Harvard Medical School
Project Title: Imaging
and Overcoming Hypoxia-Induced Resistance in Metastatic Ovarian Cancer
Brian J. Feldman, M.D., Ph.D.
Stanford University
Project Title: Using
Components of the Circadian Clock to Regulate Stem Cell Fate Decisions
Michael A. Fischbach, Ph.D.
University of California, San Francisco
Project Title: Identifying
and Characterizing Small Molecules from the Human Microbiome
M. Julia B. Felippe Flamino, D.V.M., Ph.D.
Cornelll University College of Veterinary Medicine
Project Title: Epigenetics:
A Novel Approach in Primary Immunodeficiencies
Benjamin A. Garcia, Ph.D.
Princeton University
Project Title: Novel
Methodology for Quantitative High-throughput Cancer Epigenetics
Thomas M. Guerrero, M.D., Ph.D.
The University of Texas M.D. Anderson Cancer Center
Project Title: Spatially
Accurate Deformable Image Registration for Thoracic CT Application
Monica L. Guzman, Ph.D.
Cornell University Weill Medical College
Project Title: Selection
of Novel Therapies to Ablate Chemoresistant Myeloid Leukemia Stem Cell
Amy Elizabeth Herr, Ph.D.
University of California, Berkeley
Project Title: Towards
High Throughput Proteomics: A Micro/nanofluidic Framework for Blotless Western
Technology
Julie C. Dunning Hotopp, Ph.D.
University of Maryland School of Medicine
Project Title: Impact
of Bacterial-Animal Lateral Gene Transfer on Human Health
Tony Jun Huang, Ph.D.
Pennsylvania State University
Project Title: On-Chip
Optofluidic Laser Scanning Confocal Microscope for Early Cancer Detection
Yu Huang, Ph.D.
University of California, Los Angeles
Project Title: Graphene
Nanostructures as a New Platform for Ultrasensitive Multiplexed Biologic al Sensors
Michelle Khine, Ph.D.
University of California, Irvine
Project Title: Shrink
Induced Manufacturing Platform for Low-Cost Diagnostics
Ophir D. Klein, M.D., Ph.D.
University of California, San Francisco
Project Title: An
Evolutionary-Developmental Approach to Stem Cells Using Teeth as a Model
Joshua A. Kritzer, Ph.D.
Tufts University
Project Title: Drugging
the Undruggable: Targeting Transcription Factors with Small Cyclic Peptides
Diana J. Laird, Ph.D.
University of California, San Francisco
Project Title: Cell
Competition in the Developing Mouse Germline
Erin Lavik, Sc.D.
Case Western Reserve University
Project Title: Clinically
Translatable Nanotechnology: Hemostasis and Neuroprotection
Jin Hyung Lee, Ph.D.
University of California, Los Angeles
Project Title: In
Vivo Control and Functional Visualization of Stem Cell-Driven CNS Regeneration
Hara Levy, M.D.
Medical College of Wisconsin
Project Title: Integration
of Genomics with Genetics - Molecular Phenotypes for CF Lung Disease
Ruth E. Ley, Ph.D.
Cornell University
Project Title: Development
of Immunization Strategies to Reshape Pathogenic Microbiomes
Minkui Luo, Ph.D.
Memorial Sloan-Kettering Cancer Center
Project Title: Enzyme-engineering
Approaches to Dissect Protein Methylation Profiles
Michael B. Major, Ph.D.
University of North Carolina at Chapel Hill
Project Title: Exploitation
of Near-Haploid Human Cells for Functional Gene Discovery
John C. March, Ph.D.
Cornell University
Project Title: Engineering
Commensal Bacteria as Therapeutic Signal Mediators
Timothy J. Nelson, M.D., Ph.D.
Mayo Clinic College of Medicine
Project Title: Dysfunctional
Regeneration in Cardiomyopathy: iPS-based Diagnosis and Therapy
Alexander B. Niculescu, M.D., Ph.D.
Indiana University School of Medicine
Project Title: Developing
Blood Tests for Mood Disorders
Jacquin C. Niles, M.D., Ph.D.
Massachusetts Institute of Technology
Project Title: Engineered
Regulated RNA Localization and Transport in Biological Systems
Elizabeth M. Nolan, Ph.D.
Massachusetts Institute of Technology
Project Title: Antibacterial
Peptides and Zinc in Innate Immunity and Mammalian Physiology
Manu O. Platt, Ph.D.
Georgia Institute of Technology
Project Title: Multiscale,
Mechanistic, and Predictive Models of Stroke in Sickle Cell Disease
Patrick Seale, Ph.D.
University of Pennsylvania
Project Title: Molecular
Regulation of Brown Adipose Cell Fate in Somitic Stem Cells
Balaji Sitharaman, Ph.D.
State University of New York at Stony Brook
Project Title: Nanotechnology-based
Theranostic Technology for Bone Tissue Engineering
Luke S. Theogarajan, Ph.D.
University of California, Santa Barbara
Project Title: Bio-ionic
Neural Interfaces
Budd A. Tucker, Ph.D.
The University of Iowa Carver College of Medicine
Project Title: Development
of a Cell Replacement Therapy to Treat Retinal Degenerative Blindness
Joseph Wade, Ph.D.
Wadsworth Center, New York State Department of Health / University at Albany,
State University of New York
Project Title: Pervasive
transcription in bacterial genomes
Lauren A. Weiss, Ph.D.
University of California, San Francisco
Project Title: Dissecting
Epistasis and Pleiotropy in Autism towards Personalized Medicine
Pak Kin Wong, Ph.D.
The University of Arizona
Project Title: Mechanoregulation
of Tissue Morphogenesis
Changhuei Yang, Ph.D.
California Institute of Technology
Project Title: Applications
of Time-Reverse Tissue Turbidity Suppression to Improve Biophotonics
Peng Yin, Ph.D.
Harvard University
Project Title: Engineering
Bioimaging Probes Based on Triggered Molecular Geometry
Xilin Zhao, Ph.D.
New Jersey Medical School-University of Medicine and Dentistry of New Jersey
Project Title: Anaerobic
Shock as a Novel Treatment for Tuberculosis
Sheng Zhong, Ph.D.
University of Illinois at Urbana-Champaign
Project Title: Evolutionary
Models for Gene Regulatory Networks
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