Full descriptions are available for those projects with a released
Notice of Grant Award.
Stephen G. Aller, Ph.D.
University of Alabama at Birmingham
Project Title: Streamlined Structures Of Human Integral Membrane Proteins At Atomic Resolution
Aaron B. Baker, Ph.D.
University of Texas at Austin
Project Title: Engineering Effective Revascularization Strategies For Ischemia In Disease States
Maria Barna, Ph.D.
University of California, San Francisco
Project Title: Specialized Ribosomes In Control Of Gene Expression And Embryonic Development
Uttiya Basu, Ph.D.
Columbia University
Project Title: Non-Coding RNA Engineers Antibody Diversity
Nicolas E. Buchler, Ph.D.
Duke University
Project Title: Rewiring The Yeast Brain: Redundancy And Interference In Genetic Networks
Long Cai, Ph.D.
California Institute of Technology
Project Title: Systems Biology In Single Cells By Super-Resolution Barcoding
Julie C. Canman, Ph.D.
Columbia University
Project Title: IR-LAMP: Optigenetic Technology To Spatially Manipulate Protein Function In Vivo
Erin E. Carlson, Ph.D.
Indiana University at Bloomington
Project Title: Targeted Natural Product Diversification To Identify Novel Antibacterial Agents
Edward Chang, Ph.D.
University of California, San Francisco
Project Title: Functional Architecture Of Human Speech Motor Cortex
John T. Chang, M.D.
University of California, San Diego
Project Title: Understanding The Basis For Cellular Diversity During Adaptive Immunity
Michelle C. Chang, Ph.D.
University of California, Berkeley
Project Title: Discovery And Mechanistic Study Of Fluorine Biochemistry
Wei Cheng, Ph.D.
University of Michigan at Ann Arbor
Project Title: Single Cell With One Particle Entry (SCOPE) For Study Of HIV Infection
Heather R. Christofk, Ph.D.
David Geffen School of Medicine at the University of California, Los Angeles
Project Title: Regulation Of The Warburg Effect In Cancer
Hunter B. Fraser, Ph.D.
Stanford University
Project Title: Systematic Functional Annotation Of Human Cis-Regulatory Genetic Variation
Charles A. Gersbach, Ph.D.
Duke University
Project Title: Engineering Morphogenetic Factors For Enhanced Genetic Reprogramming
Aron M. Geurts, M.D., Ph.D.
Medical College of Wisconsin
Project Title: Advanced Genetic Engineering Technology Development
Nathan C. Gianneschi, Ph.D.
University of California, San Diego
Project Title: Programming Pharmacokinetics In Vivo Via In Situ Switching Of Nanoscale Particle
Lea Goentoro, Ph.D.
California Institute of Technology
Project Title: Relative Perception In Wnt Signaling
Ming C. Hammond, Ph.D.
University Of California Berkeley
Project Title: A Chemical Biology Approach To Tagging RNAs In Live Cells
Songi Han, Ph.D.
University of California, Santa Barbara
Project Title: Probing Early Protein Aggregation Mechanisms And Their Relationship To Disease Ef
Bo Huang, Ph.D.
University of California, San Francisco
Project Title: Solving Macromolecular Complex Architecture In Situ By Super-Resolution Microscop
Christopher Hug, M.D., Ph.D.
Children’s Hospital Boston / Harvard Medical School
Project Title: Macrophage Integrated And Targeted Yeast Therapeutics
Hongrui Jiang, Ph.D.
University of Wisconsin, Madison
Project Title: Accomodative Contact Lens For Presbyopic Correction
Sundeep Kalantry, Ph.D.
University of Michigan Medical School
Project Title: Initiation Of Epigenetic Transcriptional Regulation
Andrea M. Kasko, Ph.D.
University of California, Los Angeles
Project Title: Phototunable Biomaterials To Engineer Complex 3D Cell Microenvironments
Megan C. King, Ph.D.
Yale University School of Medicine
Project Title: The Role Of Nuclear Architecture In Adaptation
Steven T. Kosak, Ph.D.
Northwestern University
Project Title: Self-Organization Of The Human Genome
Gyanu Lamichhane, Ph.D.
Johns Hopkins University
Project Title: New Drug For Treatment Of Chronic Bacterial Infection
Seok-Yong Lee, Ph.D.
Duke University School of Medicine
Project Title: Pharmacology and Biophysics of the Voltage-Gated Sodium Channel Nav 1.7
Shaun W. Lee, Ph.D.
University of Notre Dame
Project Title: Design And Use Of Novel Bacteriocins
Erez Lieberman Aiden Ph.D.
Harvard University / Broad Institute
Project Title: Exploring How The Genome Folds Through Proximity Ligation And Sequencing
Timothy Lu, M.D., Ph.D
Massachusetts Institute of Technology
Project Title: High-Throughput Nanoscale Approaches To Studying And Inhibiting Amyloid Toxicity
Emanual M. Maverakis, M.D.
University of California, Davis / VA Northern California Health Care System
Project Title: Investigation And Development Of New Therapeutic Avenues For Scleroderma
Douglas A. Mitchell, Ph.D.
University of Illinois Urbana-Champaign
Project Title: A Common Denominator Of Pathogenesis; A Rare Opportunity For Novel Therapeutic De
Harald C. Ott, M.D., Ph.D.
Massachusetts General Hospital
Project Title: Organ Engineering Based On Perfusion Decellularized Matrix
Timothy P. Padera, Ph.D.
Massachusetts General Hospital
Project Title: Characterizing Lymphatic Micrometastases: Prognostic And Therapeutic Implications
Brian M. Paegel, Ph.D.
The Scripps Research Institute
Project Title: Evolving And Engineering New Protease Tools For Mass Spectrometry Proteomics
Michael Petrascheck, Ph.D.
The Scripps Research Institute
Project Title: Modulation Of Sensory Perception To Treat Age Related Disease
Christine Queitsch, Ph.D.
University of Washington, Seattle
Project Title: Does Organismal Robustness Explain The Missing Heritability In Complex Diseases?
Arjun Raj, Ph.D.
University of Pennsylvania
Project Title: A Comprehensive Spatial Picture Of Transcription In The Nucleus
Christian D. Schlieker, Ph.D.
Yale University
Project Title: Deciphering Novel Protein Quality Control Pathways In The Nuclear Periphery
David M. Tobin, Ph.D.
Duke University
Project Title: Modulating Eicosanoids To Treat Tuberculosis: Personalized, Host-Directed Therapy
C. Jason Wang, M.D., Ph.D.
Stanford University
Project Title: Healthy Ideas Exchange
Douglas B. Weibel, Ph.D.
University of Wisconsin, Madison
Project Title: Revisiting The Bacterial Cell Wall As A Target For New Antibiotics
Rebecca A. Wingert, Ph.D.
University of Notre Dame
Project Title: Identification Of Kidney Regeneration Mechanisms Using The Zebrafish
Joy Y. Wu, M.D., Ph.D.
Massachusetts General Hospital
Project Title: In Vivo Reconstitution Of The Hematopoietic Niche
Joao Xavier, Ph.D.
Sloan-Kettering Institute for Cancer Research
Project Title: Engineering Microbial Social Interactions: Towards New Anti-Biofilm Therapies
Qi Zhang, Ph.D.
Vanderbilt University
Project Title: Explore Fundamental Aspects Of Neurotransmission With Multifunctional Nanosensor
Haining Zhong, Ph.D.
Oregon Health and Science University
Project Title: Examining The Architecture Of Synapses In Brain Tissue At Nanometer Resolution
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