|
|
|
Name of Submitter:
|
John Reed
|
|
Title of proposed idea:
|
1. Comprehensively de-orphanizing highly druggable Classes of targets, 2. Chemical modulators of the metabolome, 3. Technologies for rendering iPS cell-based models ("disease in dish") amenable to high throughput biology, 4. -generation "connectivity maps" -- multidimensional annotation of medicines
|
|
What is the major obstacle/challenge in the biomedical research field? What is needed to overcome this obstacle/challenge?
|
|
|
|
What emerging scientific opportunity is ripe for investment by the Common Fund?
|
|
|
|
What are the potential Common Fund investments that could accelerate scientific progress in this field?
|
|
|
|
If a Common Fund program on this topic achieved its objectives, what would be the impact?
|
|
|
|