Human Microbiome Project Consortium Criteria for Participation
The NIH Roadmap has organized a public research consortium named the Human Microbiome Project (HMP), with the goal of characterizing the human microbiome in normal individuals and to determine if changes in the microbiome can be correlated with health and disease. The first phase of this project, called the "jumpstart phase";, began in August 2007 with the goals of sequencing at least 500 microbial genomes, collecting samples from 250 people and performing 16S rDNA sequencing from some of those samples by mid 2009. A set of grants was funded in mid-2009 to continue the jumpstart work by sequencing at least 400 additional bacterial genomes and performing whole genome shotgun sequencing of the samples from the 250 individuals. Additionally, "demonstration project"; grants have been awarded to study the correlation between the changes in the human microbiome, during states of health and disease. A complete description of the goals and funded activities of the HMP can be found at http://nihroadmap.nih.gov/hmp/.
These core activities are supported by a Data Analysis and Coordination Center (DACC) and a set of additional grants have been awarded for developing new technologies, new software tools and studying the ethical, legal and social implications of the HMP work.
Current NIH Roadmap-funded HMP grantees are working together in a highly cooperative Consortium to rigorously analyze the human microbiome. The HMP recognizes the potential benefit afforded by including other US academic, government, and private sector scientists in this Consortium and is considering opening the group to other investigators conducting human microbiome studies and Investigators working on microbiomes in animal models. During the time that the policy for membership is being finalized, there are opportunities for groups to become temporary, adjunct members (TAMs) of the Consortium. Whereas the currently funded HMP grantees have voting rights on an HMP steering committee, the TAMs will not have voting rights. Once the policies for membership beyond temporary, adjunct membership are established, the TAMs will be notified as to their status and whether any other documents are necessary.
Criteria for participation in the HMP Consortium are the following. These are the same criteria applied to all current HMP Consortium members.
Any investigator who is interested in applying for temporary, adjunct membership to the HMP Consortium should provide to the NIH program officer of the grant, where appropriate, or to Susan Garges, NIH HMP Working Group Coordinator (firstname.lastname@example.org) (A) a description of the experimental plan s/he proposes to conduct as part of the Consortium, and (B) a statement of agreement to abide by the Criteria for Participation listed above. Items that should be included in the description of proposed work and that will be used to evaluate acceptance into the Consortium are:
For projects with multiple PIs, all PIs must submit agreements to abide by the HMP Data Release Policy and to respect the confidentiality of the consortium.
Project descriptions will be reviewed by NIH HMP staff and the HMP External Scientific Consultants to determine whether an investigator will be accepted into the Consortium. The PI(s) will be notified of acceptance as TAMs. Once the policies for membership beyond temporary, adjunct membership are established, the TAMs will be notified as to their status and whether any other documents are necessary.