- A Guide to the Epigenome
November 1, 2012
Making sense of the data deluge
- Epigenomics: The New Technologies of Chromatin Analysis
October 26, 2012
Epigenetic mechanisms influence processes from stem cell differentiation to cancer, and researcher are keen to understand how these events differ at the genomic scale– the so-called epigenome.
- Researchers unlock disease information hidden in genome’s control circuitry
September 5, 2012
Researchers at the University of Washington have determined that the majority of genetic changes associated with more than 400 common diseases and clinical traits affect the genome’s regulatory circuitry.
- Epigenome links selective mutability of the genome, human evolution and neuro-cognitive disorders
May 17, 2012
The human epigenome- the molecules and chemical modifications that decorate the human genome after the basic pattern of genomic DNA is established- marks the hotspots of structural instability in the human genome, said researchers from Baylor College of Medicine.
- Express Yourself: How Zygotes Sort Out Imprinted Genes
February 16, 2012
Researchers at the Ludwig Institute for Cancer Research, the University of California, San Diego School of Medicine and the Toronto Western Research Institute peel away some of the enduring mystery of how zygotes or fertilized eggs determine which copies of parental genes will be used or ignored.
- Embryonic And Induced-Pluripotent Stem Cells Reveal Own Molecular Signature
February 3, 2011
New discoveries in stem cell biology are fueling the development of new cell-based therapies for diseases such as Parkinson’s and diabetes where tissues may become diseased or damaged.
- Some stem cells hold on to their past, researchers say
Los Angeles Times, February 3, 2011
Stem cells created from mature cells, called induced pluripotent stem cells, retain a distinct 'memory' of their former purpose that might limit their potential for therapeutic use.
- Epigenome effort makes its mark
Nature, October 6, 2010, Vol. 467
Major release of maps charting non-genetic modifications goes beyond DNA in a bid to beat complex human disease.
- What Drives Our Genes? Researchers Map The First Complete Human Epigenome
October 15, 2009
Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated.
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