Epigenomics

Science Publications


 
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease.
Berchtold, Nicole C; Coleman, Paul D; Cribbs, David H; Rogers, Joseph; Gillen, Daniel L; Cotman, Carl W
Neurobiology of aging. 2013 Jun. 1653-61 
PMID: 23273601 [PubMed]
Multiplexed microcolumn-based process for efficient selection of RNA aptamers.
Latulippe, David R; Szeto, Kylan; Ozer, Abdullah; Duarte, Fabiana M; Kelly, Christopher V; Pagano, John M; White, Brian S; Shalloway, David; Lis, John T; Craighead, Harold G
Analytical chemistry. 2013 Mar 19. 3417-24 
PMID: 23398198 [PubMed]
Rare somatic cells from human breast tissue exhibit extensive lineage plasticity.
Roy, Somdutta; Gascard, Philippe; Dumont, Nancy; Zhao, Jianxin; Pan, Deng; Petrie, Sarah; Margeta, Marta; Tlsty, Thea D
Proceedings of the National Academy of Sciences of the United States of America. 2013 Mar 19. 4598-603 
PMID: 23487770 [PubMed]
Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes.
Lolis, Alexandra A; Londhe, Priya; Beggs, Benjamin C; Byrum, Stephanie D; Tackett, Alan J; Davie, Judith K
The Journal of biological chemistry. 2013 Mar 15. 7676-87 
PMID: 23364797 [PubMed]
Transcriptional regulation and its misregulation in disease.
Lee, Tong Ihn; Young, Richard A
Cell. 2013 Mar 14. 1237-51 
PMID: 23498934 [PubMed]
The UCSC genome browser and associated tools.
Kuhn, Robert M; Haussler, David; Kent, W James
Briefings in bioinformatics. 2013 Mar. 144-61 
PMID: 22908213 [PubMed]
Enrichment of meiotic recombination hotspot sequences by avidin capture technology.
Camara Teixeira, Daniel; Malkaram, Sridhar A; Zempleni, Janos
Gene. 2013 Mar 1. 101-6 
PMID: 23270922 [PubMed]
DNA methylation: roles in mammalian development.
Smith, Zachary D; Meissner, Alexander
Nature reviews. Genetics. 2013 Mar. 204-20 
PMID: 23400093 [PubMed]
Regulation of nucleosome dynamics by histone modifications.
Zentner, Gabriel E; Henikoff, Steven
Nature structural & molecular biology. 2013 Mar. 259-66 
PMID: 23463310 [PubMed]
RFECS: a random-forest based algorithm for enhancer identification from chromatin state.
Rajagopal, Nisha; Xie, Wei; Li, Yan; Wagner, Uli; Wang, Wei; Stamatoyannopoulos, John; Ernst, Jason; Kellis, Manolis; Ren, Bing
PLoS computational biology. 2013 Mar. e1002968 
PMID: 23526891 [PubMed]
The simplest explanation: passive DNA demethylation in PGCs.
Smith, Zachary D; Meissner, Alexander
The EMBO journal. 2013 Feb 6. 318-21 
PMID: 23299938 [PubMed]
Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer.
Diyabalanage, Himashinie V K; Granda, Michael L; Hooker, Jacob M
Cancer letters. 2013 Feb 1. 1-8 
PMID: 23032720 [PubMed]
Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes.
Caravaca, Juan Manuel; Donahue, Greg; Becker, Justin S; He, Ximiao; Vinson, Charles; Zaret, Kenneth S
Genes & development. 2013 Feb 1. 251-60 
PMID: 23355396 [PubMed]
Regulation of Drosophila metamorphosis by xenobiotic response regulators.
Deng, Huai; Kerppola, Tom K
PLoS genetics. 2013 Feb. e1003263 
PMID: 23408904 [PubMed]
ISWI and CHD Chromatin Remodelers Bind Promoters but Act in Gene Bodies.
Zentner, Gabriel E; Tsukiyama, Toshio; Henikoff, Steven
PLoS genetics. 2013 Feb. e1003317 
PMID: 23468649 [PubMed]
Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability.
Harris, R Alan; Shaw, Chad; Li, Jian; Cheung, Sau Wai; Coarfa, Cristian; Jeong, Mira; Goodell, Margaret A; White, Lisa D; Patel, Ankita; Kang, Sung-Hae; Chinault, A Craig; Gambin, Tomasz; Gambin, Anna; Lupski, James R; Milosavljevic, Aleksandar
PLoS genetics. 2013 Feb. e1003333 
PMID: 23468659 [PubMed]
Genome-wide chromatin state transitions associated with developmental and environmental cues.
Zhu, Jiang; Adli, Mazhar; Zou, James Y; Verstappen, Griet; Coyne, Michael; Zhang, Xiaolan; Durham, Timothy; Miri, Mohammad; Deshpande, Vikram; De Jager, Philip L; Bennett, David A; Houmard, Joseph A; Muoio, Deborah M; Onder, Tamer T; Camahort, Ray; Cowan,
Cell. 2013 Jan 31. 642-54 
PMID: 23333102 [PubMed]
Hypomethylation of Noncoding DNA Regions and Overexpression of the Long Noncoding RNA, AFAP1-AS1, in Barrett's Esophagus and Esophageal Adenocarcinoma.
Wu, Wenjing; Bhagat, Tushar D; Yang, Xue; Song, Jee Hoon; Cheng, Yulan; Agarwal, Rachana; Abraham, John M; Ibrahim, Sariat; Hussain, Zulfiqar; Suzuki, Masako; Yu, Yiting; Eng, Charis; Greally, John; Verma, Amit; Meltzer, Stephen J
Gastroenterology. 2013 Jan 16.  
PMID: 23333711 [PubMed]
Functional characterization of piggyBat from the bat Myotis lucifugus unveils an active mammalian DNA transposon.
Mitra, Rupak; Li, Xianghong; Kapusta, Aurelie; Mayhew, David; Mitra, Robi D; Feschotte, Cedric; Craig, Nancy L
Proceedings of the National Academy of Sciences of the United States of America. 2013 Jan 2. 234-9 
PMID: 23248290 [PubMed]
Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.
Fass, Daniel M; Reis, Surya A; Ghosh, Balaram; Hennig, Krista M; Joseph, Nadine F; Zhao, Wen-Ning; Nieland, Thomas J F; Guan, Ji-Song; Kuhnle, Chelsea E Groves; Tang, Weiping; Barker, Douglas D; Mazitschek, Ralph; Schreiber, Stuart L; Tsai, Li-Huei; Hagga
Neuropharmacology. 2013 Jan. 81-96 
PMID: 22771460 [PubMed]
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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892