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Unhealthy behaviors—such as smoking, drug and alcohol abuse, overeating, and a sedentary lifestyle— contribute to negative health outcomes and common diseases. These types of behaviors account for approximately 40 percent of the risk associated with preventable premature deaths in the United States. Unfortunately, it is extremely difficult to initiate and maintain healthy behavior changes over an extended period of time.

The Common Fund’s Science of Behavior Change program aims to improve our understanding of behavior change across a broad range of health-related behaviors. The program supports research that integrates basic and translational science and cuts across many disciplines. The SOBC program seeks to implement a mechanisms-focused approach to behavior change research and to develop the tools required to implement such an approach. One particular health behavior—adherence to medical regimens—provides particularly compelling test of this approach. Non-adherence to medical regimens is a significant health problem that serves as an example for the general behavioral intervention goal of initiating and maintaining behavior change.

Stage 1 of the SOBC program sought to improve our understanding of basic mechanisms of human behavior change across a broad array of health-related behaviors and to use this knowledge to develop more effective behavioral interventions. Research funded during Stage 1 led to the identification of three broad classes of intervention targets that are highly relevant to understanding the mechanisms of behavior change: self-regulationstress reactivity and stress resilience, and interpersonal and social processes

The second stage of the program, the SOBC Research Network, began in fiscal year 2015 and will continue to build on knowledge gained from the first successful stage of the program. The SOBC Research Network consists of eight teams of researchers studying the basic mechanisms of human behavior change as well as a Coordinating Center at Columbia University Health Sciences.


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