Building Blocks, Biological Pathways and Networks

Science Publications


 
Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons.
Melo, C V; Okumoto, S; Gomes, J R; Baptista, M S; Bahr, B A; Frommer, W B; Duarte, C B
Neuroscience. 2013 May 1. 66-86 
PMID: 23384605 [PubMed]
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
Ulanovskaya, Olesya A; Zuhl, Andrea M; Cravatt, Benjamin F
Nature chemical biology. 2013 May. 300-6 
PMID: 23455543 [PubMed]
Simulation of triacylglycerol ion profiles: bioinformatics for interpretation of triacylglycerol biosynthesis.
Han, Rowland H; Wang, Miao; Fang, Xiaoling; Han, Xianlin
Journal of lipid research. 2013 Apr. 1023-32 
PMID: 23365150 [PubMed]
Determining target engagement in living systems.
Simon, Gabriel M; Niphakis, Micah J; Cravatt, Benjamin F
Nature chemical biology. 2013 Apr. 200-5 
PMID: 23508173 [PubMed]
Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry.
Nemes, Peter; Rubakhin, Stanislav S; Aerts, Jordan T; Sweedler, Jonathan V
Nature protocols. 2013 Apr. 783-99 
PMID: 23538882 [PubMed]
Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry.
Nemes, Peter; Rubakhin, Stanislav S; Aerts, Jordan T; Sweedler, Jonathan V
Nature protocols. 2013 Apr. 783-99 
PMID: 23589938 [PubMed]
Combining small-volume metabolomic and transcriptomic approaches for assessing brain chemistry.
Knolhoff, Ann M; Nautiyal, Katherine M; Nemes, Peter; Kalachikov, Sergey; Morozova, Irina; Silver, Rae; Sweedler, Jonathan V
Analytical chemistry. 2013 Mar 19. 3136-43 
PMID: 23409944 [PubMed]
Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.
Li, Xiang; Foley, Emily A; Kawashima, Shigehiro A; Molloy, Kelly R; Li, Yinyin; Chait, Brian T; Kapoor, Tarun M
Protein science : a publication of the Protein Society. 2013 Mar. 287-95 
PMID: 23281010 [PubMed]
Network motifs provide signatures that characterize metabolism.
Shellman, Erin R; Burant, Charles F; Schnell, Santiago
Molecular bioSystems. 2013 Mar. 352-60 
PMID: 23287894 [PubMed]
Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells.
Hulce, Jonathan J; Cognetta, Armand B; Niphakis, Micah J; Tully, Sarah E; Cravatt, Benjamin F
Nature methods. 2013 Mar. 259-64 
PMID: 23396283 [PubMed]
Access guide to human proteinpedia.
Muthusamy, Babylakshmi; Thomas, Joji Kurian; Prasad, T S Keshava; Pandey, Akhilesh
Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]. 2013 Mar. Unit1.21 
PMID: 23504933 [PubMed]
A role for the nucleoporin Nup170p in chromatin structure and gene silencing.
Van de Vosse, David W; Wan, Yakun; Lapetina, Diego L; Chen, Wei-Ming; Chiang, Jung-Hsien; Aitchison, John D; Wozniak, Richard W
Cell. 2013 Feb 28. 969-83 
PMID: 23452847 [PubMed]
Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate.
Harris, Stephanie R; Zhang, Guo-Fang; Sadhukhan, Sushabhan; Wang, Hua; Shi, Chuan; Puchowicz, Michelle A; Anderson, Vernon E; Salomon, Robert G; Tochtrop, Gregory P; Brunengraber, Henri
Chemical research in toxicology. 2013 Feb 18. 213-20 
PMID: 23171137 [PubMed]
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio, Michela; Callen, Elsa; Yamane, Arito; Zhang, Wenzhu; Jankovic, Mila; Gitlin, Alexander D; Feldhahn, Niklas; Resch, Wolfgang; Oliveira, Thiago Y; Chait, Brian T; Nussenzweig, Andre; Casellas, Rafael; Robbiani, Davide F; Nussenzweig, Michel C
Science (New York, N.Y.). 2013 Feb 8. 711-5 
PMID: 23306439 [PubMed]
Proteomics for understanding miRNA biology.
Huang, Tai-Chung; Pinto, Sneha M; Pandey, Akhilesh
Proteomics. 2013 Feb. 558-67 
PMID: 23125164 [PubMed]
Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus.
Lee, Ji Eun; Zamdborg, Leonid; Southey, Bruce R; Atkins Jr, Norman; Mitchell, Jennifer W; Li, Mingxi; Gillette, Martha U; Kelleher, Neil L; Sweedler, Jonathan V
Journal of proteome research. 2013 Feb 1. 585-93 
PMID: 23256577 [PubMed]
High-throughput flow cytometry compatible biosensor based on fluorogen activating protein technology.
Wu, Yang; Tapia, Phillip H; Fisher, Gregory W; Waggoner, Alan S; Jarvik, Jonathan; Sklar, Larry A
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2013 Feb. 220-6 
PMID: 23303704 [PubMed]
Neuronal metabolomics by ion mobility mass spectrometry: cocaine effects on glucose and selected biogenic amine metabolites in the frontal cortex, striatum, and thalamus of the rat.
Kaplan, Kimberly A; Chiu, Veronica M; Lukus, Peter A; Zhang, Xing; Siems, William F; Schenk, James O; Hill Jr, Herbert H
Analytical and bioanalytical chemistry. 2013 Feb. 1959-68 
PMID: 23314481 [PubMed]
Interactome mapping: using protein microarray technology to reconstruct diverse protein networks.
Uzoma, Ijeoma; Zhu, Heng
Genomics, proteomics & bioinformatics. 2013 Feb. 18-28 
PMID: 23395178 [PubMed]
Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor.
Han, Bingnan; Wright, Rachel; Kirchhoff, Aaron M; Chester, Julia A; Cooper, Bruce R; Davisson, Vincent Jo; Barker, Eric
Analytical biochemistry. 2013 Jan 15. 74-81 
PMID: 23044255 [PubMed]
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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892