Building Blocks, Biological Pathways and Networks

National Technology Centers for Networks and Pathways


Renewal of the National Technology Centers for Networks and Pathways Program (U54)
RFA-RM-08-021
PI Name Institution Name Title
BOEKE, JEF D. JOHNS HOPKINS UNIVERSITY Networks, Pathways and Dynamics of Lysine Modification
ROUT, MICHAEL P ROCKEFELLER UNIVERSITY New Tools for Exploring the Dynamic Interactome (Renewal)
WAGGONER, ALAN S CARNEGIE-MELLON UNIVERSITY Fluorescent Biosensors for Networks and Pathways

National Technology Centers for Networks and Pathways (U54)
RFA-RM-04-005
PI Name Institution Name Title
BOEKE, JEF D JOHNS HOPKINS UNIVERSITY Networks and Pathways of Lysine Modification
SMITH, JEFFREY W BURNHAM INSTITUTE Center on Proteolytic Pathways

National Technology Centers for Networks and Pathways (Re-issuance) (U54)
RFA-RM-04-019
PI Name Institution Name Title
LOEW, LESLIE M. UNIVERSITY OF CONNECTICUT SCH OF MED/DNT POLARITY IN NETWORKS AND PATHWAYS
ROUT, MICHAEL P. ROCKEFELLER UNIVERSITY New Tools for Exploring the Dynamic Interactome
WAGGONER, ALAN S. MELLON PITTS CORPORATION (MPC CORP) Flourescent Probes & Imaging for Networks & Pathways

Metabolomics Technology Development


Using Metabolomics to Investigate Biological Pathways and Networks (R01)
RFA-RM-06-010
PI Name Institution Name Title
BURANT, CHARLES F UNIVERSITY OF MICHIGAN AT ANN ARBOR Using Systems Biology to Understand Islet Adaptation and Failure Diabetes
CRAVATT, BENJAMIN F SCRIPPS RESEARCH INSTITUTE Chemical Probes for Metabolic Pathway Discovery in Human Disease
DOVICHI, NORMAN J UNIVERSITY OF WASHINGTON Glycolipid metabolism in single cells
FREYER, JAMES P LOS ALAMOS NAT SECTY-LOS ALAMOS NAT LAB Differential metabolic network analysis of tumor progression
FROMMER, WOLF B CARNEGIE INSTITUTION OF WASHINGTON, D.C. Sugar signaling networks detected by high content fluxomics
HAN, XIANLIN WASHINGTON UNIVERSITY Shotgun Lipidomics and Alterations in Sphingolipidomes in Alzheimer's Diseases
SWEEDLER, JONATHAN V UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN The Neurometabolome of a Sensory Neuronal Network

Metabolomics Technology Development (R21, R33)
RFA-RM-04-002
PI Name Institution Name Title
BREAKER, RONALD YALE UNIVERSITY Measuring Metabolites Using Riboswitch Reports
BROWN, TRUMAN R COLUMBIA UNIVERSITY HEALTH SCIENCES Metabolic Patterns in 1H NMR Spectra of Biofluids
BRUNENGRABER, HENRI CASE WESTERN RESERVE UNIVERSITY Dynamic Metabolomics via Isotopomer Analysis
DOVICHI, NORMAN J UNIVERSITY OF WASHINGTON GLYCOLIPID METABOLISM IN SINGLE CELLS
GRIFFIN, JULIAN L UNIVERSITY OF CAMBRIDGE Metabolomics and Metabolomic Compartmentation in the Brain
HILL, HERBERT H WASHINGTON STATE UNIVERSITY High Resolution Ion Mobility Mass Spectrometry (IMMS)
KLEINFELD, ALAN M FFA SCIENCES, LLC Fluorescent Probes for Hydrophobic Metabolites
LIAO, JAMES C UNIVERSITY OF CALIFORNIA LOS ANGELES Automated Chip-Based Metabolic Analysis
MATSON, WAYNE R ESA, INC Integrating LCE/LCM In a Single Metabolomics Plataform
REGNIER, FRED E PURDUE UNIVERSITY WEST LAFAYETTE Tools for Differential Metabolomics
SUSSMAN, MICHAEL R UNIVERSITY OF WISCONSON MADISON Isotope-Assisted Differential Metabolomics
SWEEDLER, JONATHAN V UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN Technologies for Cellular Neurometabolomics
WAGNER, GERHARD HARVARD UNIVERSITY (MEDICAL SCHOOL) Integrated & Sensitive Metabolomics Platform/Human disease
YORK, JOHN D DUKE UNIVERSITY Biological Oscilloscopes Spatio-Temporal Metabolomics



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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892