Transformative R01 Program

MODELING HUMAN HEPATOTROPIC INFECTIONS IN COMPLEX TISSUE ORGANOIDS

MODELING HUMAN HEPATOTROPIC INFECTIONS IN COMPLEX TISSUE ORGANOIDS

​​Evidence for the presence of bile canaliculi between adjacent primary human hepatocytes in micropatterned co-cultures (MPCCs). Three-dimensional confocal rendering of primary hepatocytes stained for multidrug resistant protein 2 (green), zona occludens protein (red) and nuclei (blue).