Roadmap
Transformative Research Projects Program (R01)
RFA-RM-09-022 |
PI
Name |
Institution
Name |
Title |
ARLOTTA, PAOLA (contact) JOUNG, J.
KEITH ZHANG, FENG |
MASSACHUSETTS GENERAL HOSPITAL |
Genome-wide Light-inducible Tuning of
Transcriptional Network Dynamic |
BLASER, MARTIN J |
NEW YORK UNIVERSITY SCHOOL OF
MEDICINE |
Disappearing gastrointestinal microbiota in epidemic obesity |
COUKOS, GEORGE |
UNIVERSITY OF PENNSYLVANIA |
Transformative personalized vascular
disrupting cancer immunotherapy |
ELLINGTON, ANDREW D |
UNIVERSITY OF TEXAS AUSTIN |
DNA circuits for point-of-care diagnostics |
FLAVELL, RICHARD A (contact)
DHODAPKAR, MADHAV V |
YALE UNIVERSITY |
Understanding Hemotopoietic Neoplasias using Humanized Mice |
GREEN, PAMELA J |
UNIVERSITY OF DELAWARE |
Global Analysis of the Human RNA Degradome |
GRUTZENDLER, JAIME |
NORTHWESTERN UNIVERSITY |
Embolus extravasation:
an alternative mechanism of microvascular recanalization |
KEATING, AMY E |
MASSACHUSETTS INSTITUTE OF
TECHNOLOGY |
Very large datasets and new models to
predict and design protein interactions |
NICKELS, BRYCE EDWARD (contact)
DOVE, SIMON L |
RUTGERS THE ST UNIV OF NJ NEW
BRUNSWICK |
NanoRNA-mediated control of gene expression |
NICOLELIS, MIGUEL A. L. |
DUKE UNIVERSITY |
Dorsal Column Stimulation as a New Therapy
for Motor Disorders |
OLTZ, EUGENE M. (contact) PAYTON,
JACQUELINE E |
WASHINGTON UNIVERSITY |
Targeting Epigenomic Signatures in Non-Hodgkin Lymphoma for Novel Therapeutics |
PELTZ, GARY A |
STANFORD UNIVERSITY |
Human Pharmacogenetics and Human Liver Regeneration |
SHAHAM, SHAI |
ROCKEFELLER UNIVERSITY |
Glial control of neuronal receptive ending
morphology |
WANG, LIGUO |
YALE UNIVERSITY |
Structure of a membrane protein in a lipid
membrane: cryo-EM study of the HCN cha |
WEINER, DAVID B |
UNIVERSITY OF PENNSYLVANIA |
Development of a Universal Influenza Seasonal
Vaccine |
WERNIG, MARIUS (contact) SUDHOF,
THOMAS C |
STANFORD UNIVERSITY |
Direct conversion of fibroblasts into
neurons: A novel approach to study neuropsy |
YANIK, MEHMET FATIH |
MASSACHUSETTS INSTITUTE OF
TECHNOLOGY |
High-Throughput in Vivo Subcellular-Resolution
Vertebrate Screening Platform |
ZADOR, ANTHONY M |
COLD SPRING HARBOR LABORATORY |
High-throughput DNA sequencing method for
probing the connectivity of neural circ |
ZHANG, KANG (contact) DING, SHENG
REH, THOMAS A |
UNIVERSITY OF CALIFORNIA SAN DIEGO |
Regeneration of Retinal Neurons by
Chemically Induced Reprogramming of Muller Gli |
ZHUANG, XIAOWEI (contact) XIE,
XIAOLIANG SUNNEY |
HARVARD UNIVERSITY |
Dynamic cellular architecture of bacteria by
system-wide super-resolution imaging |
Roadmap Transformative R01
Program (R01)
RFA-RM
08-029 |
PI
Name |
Institution
Name |
Title |
AUSUBEL, FREDERICK M |
MASSACHUSETTS GENERAL HOSPITAL |
Identifying novel anti-infectives by high through-put screening in whole animals |
.BRETON, SYLVIE |
MASSACHUSETTS GENERAL HOSPITAL |
3-Dimensional modeling of basal cell
function in pseudostratified epithelia |
CAMARERO, JULIO A |
UNIVERSITY OF SOUTHERN CALIFORNIA |
Cell-based screening and selection of cyclotide-based capture reagents for protein profiling
using micro-array format |
COHEN, PINCHAS |
UNIVERSITY OF CALIFORNIA LOS
ANGELES |
Novel Mitochondrially Encoded Peptides and Their Role in Health and Disease |
CRAVATT, BENJAMIN F. (contact);
KODADEK, THOMAS J |
SCRIPPS RESEARCH INSTITUTE |
Massively Parallel Identification of Protein Ligands |
CZECH, MICHAEL P |
UNIV OF MASSACHUSETTS MED SCH WORCESTER |
Oral Delivery Vehicles for RNAi Therapies |
DANUSER, GAUDENZ (contact);
HAHN, KLAUS MICHAEL |
SCRIPPS RESEARCH INSTITUTE |
Quantitative Imaging of Signaling Networks |
DUBNAU, JOSHUA T |
COLD SPRING HARBOR LABORATORY |
Genome-wide regulatory network governing
neuronal mRNA translation. |
FIDOCK, DAVID ARMAND |
COLUMBIA UNIVERSITY HEALTH
SCIENCES |
Exploiting Fatty Acid Metabolism To Cure
Malaria |
GRIFFITH, LINDA G. |
MASSACHUSETTS INSTITUTE OF
TECHNOLOGY |
Perfused 3D Tissue Surrogates for Complex Cell-Cell
Communication Systems |
HOFFMAN, ANDREW R |
STANFORD UNIVERSITY |
Role of Long-Range Chromatin Interactions in
Genetic Disease |
YENGAR, SRINIVAS RAVI V (contact);
HE, JOHN C
HONE, JAMES C
LOEW, LESLIE M
NEVES, SUSANA R |
MOUNT SINAI SCHOOL OF MEDICINE OF
NYU |
Dynamics Underlying Tissue Integrity |
JAFFREY, SAMIE R |
WEILL MEDICAL COLLEGE OF CORNELL
UNIV |
Novel fluorescent sensors for simple,
sensitive, and specific protein detection |
JI, RU-RONG (contact)
SERHAN, CHARLES NICHOLAS |
BRIGHAM AND WOMEN'S HOSPITAL |
Resolvins, protectins, and
chronic pain resolution |
KOIDE, SHOHEI |
UNIVERSITY OF CHICAGO |
Rational generation of directed
protein-capture reagents |
KUO, CALVIN J |
STANFORD UNIVERSITY |
Three-dimensional Scaffold-based Systems for
Primary Human Intestinal Culture |
LAGASSE, ERIC |
VA PALO ALTO HEALTH CARE SYSTEM |
Organogenesis of Ectopic Tissue in Lymph Node |
LEE, BRENDAN HL |
BAYLOR COLLEGE OF MEDICINE |
Argininosuccinate Lyase is an
essential regulator of systemic nitric oxide production |
LEE, FRANK S |
UNIVERSITY OF PENNSYLVANIA |
The Hydroxylprolylproteome |
LEWIS, KIM |
NORTHEASTERN UNIVERSITY |
Super-persistent cells and the paradox of
untreatable infections |
LI, LONG-CHENG (contact);
LI, HAO |
UNIVERSITY OF CALIFORNIA SAN
FRANCISCO |
Transcriptional Activation by Small RNA:
Mechanism and Design Rules |
LIS, JOHN T (contact);
CRAIGHEAD, HAROLD G
JIN, MOONSOO M |
CORNELL UNIVERSITY |
Development of High Throughput Aptamer-based Protein Capture/Detection Assays towards
Comprehensive Analysis of Human Proteome |
MACIEJEWSKI, JAROSLAW P |
CLEVELAND CLINIC LERNER COLLEGE OF
MEDICINE |
Viral Pathogenesis of Idiopathic Bone Marrow
Failure and Immune Cytopenias |
MARGOLIS, PETER ADAM (contact);
SEID, MICHAEL |
CHILDREN'S HOSPITAL MEDICAL CTR
(CINCINNATI) |
Open Source Science: Transforming Chronic
Illness Care |
MARKOVITZ, DAVID MICHAEL |
UNIVERSITY OF MICHIGAN AT ANN
ARBOR |
Replication of Human Endogenous Retroviruses
in Modern Humans |
MARKOWITZ, SANFORD D |
CASE WESTERN RESERVE UNIVERSITY |
Identifying Inborn Genetic Susceptibility to
Development of Cancer Metastasis |
MARSHALL, WALLACE |
UNIVERSITY OF CALIFORNIA SAN
FRANCISCO |
Pattern formation & regeneration in a single
cell |
MITRA, PARTHA PRATIM |
COLD SPRING HARBOR LABORATORY |
The Missing Circuit: The First Brainwide Connectivity Map for Mouse |
MURDOCK, DEBORAH G |
VANDERBILT UNIVERSITY MEDICAL
CENTER |
Fatty acid signals as quorum sensing
regulators of mitochondrial biogenesis |
MURPHY, SHEILA T. (contact);
BAEZCONDE GARBANATI, LOURDES ALBERTINA
BALL-ROKEACH, SANDRA
HAILE, ROBERT WILLIAM |
UNIVERSITY SOUTHERN CALIFORNIA |
Transforming Cancer Knowledge, Attitudes and
Behavior through Narrative |
NISWENDER, KEVIN D (contact);
GALLI, AURELIO ANTONIO |
VANDERBILT UNIVERSITY |
Insulin regulation of monoamine signaling:
pathway to obesity |
PARSONNET, JULIE |
STANFORD UNIVERSITY |
Childhood infection and prevention of obesity |
POLLACK, GERALD H |
UNIVERSITY OF WASHINGTON |
Unexpectedly Profound Role of Water in
Biology and Medicine |
RICE, CHARLES M. (contact);
BHATIA, SANGEETA N. |
ROCKEFELLER UNIVERSITY |
Modeling human hepatotropic infections in complex tissue organoids |
ROBERTS, RICHARD W (contact);
SOH, HYONGSOK TOM |
UNIVERSITY SOUTHERN CALIFORNIA |
Polypeptide Design with Proteomic Scope via Microfluidic mRNA Display |
SUKI, BELA |
BOSTON UNIVERSITY |
Regulatory roles of variable mechanical
stimuli in cell function |
TEWARI, MUNEESH |
FRED HUTCHINSON CANCER RESEARCH
CENTER |
RNA as a Hormone: Systemic Signaling in
Mammals via Circulating, Cell-Free Small |
WALENSKY, LOREN D |
DANA-FARBER CANCER INSTITUTE |
A Lexicon of Stapled Peptide Helices
Engineered to Capture the Protein Interactome |
WILSON, ROBERT B |
UNIVERSITY OF PENNSYLVANIA |
Random shRNA Selection |
WU, JOSEPH C |
STANFORD UNIVERSITY |
Re-Education of the Immune System for hES Cell Tolerance |
XIE, XIAOLIANG SUNNEY |
HARVARD UNIVERSITY |
maging the Invisible with No Labels: A Major
Opportunity in Biology and Medicine |
ZYLKA, MARK JOHN |
UNIVERSITY OF NORTH CAROLINA
CHAPEL HILL |
Harnessing ectonucleotidases to treat chronic pain |
