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Metabolomics (182)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.the KORA study groupEuropean journal of human genetics : EJHG2014 Feb 12NULL24518831
X13CMS: global tracking of isotopic labels in untargeted metabolomics.Huang, Xiaojing; Chen, Ying-Jr; Cho, Kevin; Nikolskiy, Igor; Crawford, Peter A; Patti, Gary JAnalytical chemistry2014 Feb 41632-924397582
Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2014 Feb-Mar27-3724411718
Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation.Whiteson, Katrine L; Meinardi, Simone; Lim, Yan Wei; Schmieder, Robert; Maughan, Heather; Quinn, Robert; Blake, Donald R; Conrad, Douglas; Rohwer, ForestThe ISME journal2014 Jan 9NULL24401860
Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.de Boer, Ian H; DCCT/EDIC Research GroupDiabetes care2014 Jan24-3024356594
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.Campbell, Caitlin; Grapov, Dmitry; Fiehn, Oliver; Chandler, Carol J; Burnett, Dustin J; Souza, Elaine C; Casazza, Gretchen A; Gustafson, Mary B; Keim, Nancy L; Newman, John W; Hunter, Gary R; Fernandez, Jose R; Garvey, W Timothy; Harper, Mary-Ellen; HoppePloS one2014e8426024416208
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Theriot, Casey M; Koenigsknecht, Mark J; Carlson Jr, Paul E; Hatton, Gabrielle E; Nelson, Adam M; Li, Bo; Huffnagle, Gary B; Z Li, Jun; Young, Vincent BNature communications2014311424445449
Isotopic Ratio Outlier Analysis Global Metabolomics of Caenorhabditis elegans.Stupp, Gregory S; Clendinen, Chaevien S; Ajredini, Ramadan; Szewc, Mark A; Garrett, Timothy; Menger, Robert F; Yost, Richard A; Beecher, Chris; Edison, Arthur SAnalytical chemistry2013 Dec 1711858-6524274725
Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis.Gardell, Alison M; Yang, Jun; Sacchi, Romina; Fangue, Nann A; Hammock, Bruce D; Kultz, DietmarThe Journal of experimental biology2013 Dec 154615-2524072790
A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat.Ament, Zsuzsanna; Waterman, Claire L; West, James A; Waterfield, Catherine; Currie, Richard A; Wright, Jayne; Griffin, Julian LJournal of proteome research2013 Dec 65775-9024161236
Constipation and a low-fiber diet are not associated with diverticulosis.Peery, Anne F; Sandler, Robert S; Ahnen, Dennis J; Galanko, Joseph A; Holm, Adrian N; Shaukat, Aasma; Mott, Leila A; Barry, Elizabeth L; Fried, David A; Baron, John AClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013 Dec1622-723891924
Division of mitochondria in cultured human fibroblasts.Fujioka, Hisashi; Tandler, Bernard; Consolo, Mary C; Karnik, PratimaMicroscopy research and technique2013 Dec1213-624009193
Human milk secretory immunoglobulin a and lactoferrin N-glycans are altered in women with gestational diabetes mellitus.Smilowitz, Jennifer T; Totten, Sarah M; Huang, Jincui; Grapov, Dmitry; Durham, Holiday A; Lammi-Keefe, Carol J; Lebrilla, Carlito; German, J BruceThe Journal of nutrition2013 Dec1906-1224047700
Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice.Zhang, Wanying; Li, Haonan; Dong, Hua; Liao, Jie; Hammock, Bruce D; Yang, Guang-YuAnticancer research2013 Dec5261-7124324059
Silibinin inhibits hepatitis C virus entry into hepatocytes by hindering clathrin-dependent trafficking.Blaising, Julie; Levy, Pierre L; Gondeau, Claire; Phelip, Capucine; Varbanov, Mihayl; Teissier, Elodie; Ruggiero, Florence; Polyak, Stephen J; Oberlies, Nicholas H; Ivanovic, Tijana; Boulant, Steeve; Pecheur, Eve-IsabelleCellular microbiology2013 Nov1866-8223701235
Microarray analysis of androgenetic and senescent alopecia: comparison of gene expression shows two distinct profiles.Karnik, Pratima; Shah, Selam; Dvorkin-Wininger, Yevgeniya; Oshtory, Shaheen; Mirmirani, ParadiJournal of dermatological science2013 Nov183-623886704
Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola.Van Bogaert, Inge; Zhang, Guodong; Yang, Jun; Liu, Jun-Yan; Ye, Yonghao; Soetaert, Wim; Hammock, Bruce DJournal of lipid research2013 Nov3215-923966667
LC-IMS-MS Feature Finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets.Crowell, Kevin L; Slysz, Gordon W; Baker, Erin S; LaMarche, Brian L; Monroe, Matthew E; Ibrahim, Yehia M; Payne, Samuel H; Anderson, Gordon A; Smith, Richard DBioinformatics (Oxford, England)2013 Nov 12804-524008421
Vitamin D3 supplementation and upper respiratory tract infections in a randomized, controlled trial.Rees, Judy R; Hendricks, Kristy; Barry, Elizabeth L; Peacock, Janet L; Mott, Leila A; Sandler, Robert S; Bresalier, Robert S; Goodman, Michael; Bostick, Roberd M; Baron, John AClinical infectious diseases : an official publication of the Infectious Diseases Society of America2013 Nov1384-9224014734
Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.Ghanta, Sirisha; Grossmann, Ruth E; Brenner, CharlesCritical reviews in biochemistry and molecular biology2013 Nov-Dec561-7424050258
Vitamin D deficiency: consequence or cause of CKD?de Boer, Ian H; Thadhani, RaviClinical journal of the American Society of Nephrology : CJASN2013 Nov1844-624135217
Hepatic fatty acid trafficking: multiple forks in the road.Mashek, Douglas GAdvances in nutrition (Bethesda, Md.)2013 Nov697-71024228201
Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer.Wooding, Kerry M; Barkley, Robert M; Hankin, Joseph A; Johnson, Christopher A; Bradford, Andrew P; Santoro, Nanette; Murphy, Robert CJournal of the American Society for Mass Spectrometry2013 Oct1451-523955001
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.Frolov, Andrey; Yang, Lihua; Dong, Hua; Hammock, Bruce D; Crofford, Leslie JProstaglandins, leukotrienes, and essential fatty acids2013 Oct351-824055573
A Computational Framework for High-Throughput Isotopic Natural Abundance Correction of Omics-Level Ultra-High Resolution FT-MS Datasets.Carreer, William J; Flight, Robert M; Moseley, Hunter N BMetabolites2013 Sep 25NULL24404440
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate.Davda, Dahvid; El Azzouny, Mahmoud A; Tom, Christopher T M B; Hernandez, Jeannie L; Majmudar, Jaimeen D; Kennedy, Robert T; Martin, Brent RACS chemical biology2013 Sep 201912-723844586
Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third national health and nutrition examination survey.Hernaez, Ruben; McLean, Jody; Lazo, Mariana; Brancati, Frederick L; Hirschhorn, Joel N; Borecki, Ingrid B; Harris, Tamara B; Genetics of Obesity-Related Liver Disease (GOLD) Consortium; Nguyen, Thutrang; Kamel, Ihab R; Bonekamp, Susanne; Eberhardt, Mark SClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013 Sep1183-1190.e223416328
Cortisol response to operative stress with anesthesia in healthy children.Taylor, Lisa K; Auchus, Richard J; Baskin, Laurence S; Miller, Walter LThe Journal of clinical endocrinology and metabolism2013 Sep3687-9323861461
An untargeted metabolomic workflow to improve structural characterization of metabolites.Nikolskiy, Igor; Mahieu, Nathaniel G; Chen, Ying-Jr; Tautenhahn, Ralf; Patti, Gary JAnalytical chemistry2013 Aug 207713-923829391
Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.Frolov, Andrey; Dong, Hua; Jiang, Min; Yang, Lihua; Cook, Erik C; Matnani, Rahul; Hammock, Bruce D; Crofford, Leslie JThe Journal of biological chemistry2013 Aug 1623696-70323814065
Mechanistic study of the biomimetic synthesis of flavonolignan diastereoisomers in milk thistle.Althagafy, Hanan S; Meza-Avina, Maria Elena; Oberlies, Nicholas H; Croatt, Mitchell PThe Journal of organic chemistry2013 Aug 27594-60023876147
Circulating vitamin D metabolites and subclinical atherosclerosis in type 1 diabetes.Sachs, Michael C; Brunzell, John D; Cleary, Patricia A; Hoofnagle, Andrew N; Lachin, John M; Molitch, Mark E; Steffes, Michael W; Zinman, Bernard; de Boer, Ian H; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and ComplicaDiabetes care2013 Aug2423-923530012
LipidBlast in silico tandem mass spectrometry database for lipid identification.Kind, Tobias; Liu, Kwang-Hyeon; Lee, Do Yup; Defelice, Brian; Meissen, John K; Fiehn, OliverNature methods2013 Aug755-823817071
Nutritional lipidomics: molecular metabolism, analytics, and diagnostics.Smilowitz, Jennifer T; Zivkovic, Angela M; Wan, Yu-Jui Yvonne; Watkins, Steve M; Nording, Malin L; Hammock, Bruce D; German, J BruceMolecular nutrition & food research2013 Aug1319-3523818328
Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass.Saeidi, Nima; Meoli, Luca; Nestoridi, Eirini; Gupta, Nitin K; Kvas, Stephanie; Kucharczyk, John; Bonab, Ali A; Fischman, Alan J; Yarmush, Martin L; Stylopoulos, NicholasScience (New York, N.Y.)2013 Jul 26406-1023888041
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.Asai, Masato; Ramachandrappa, Shwetha; Joachim, Maria; Shen, Yuan; Zhang, Rong; Nuthalapati, Nikhil; Ramanathan, Visali; Strochlic, David E; Ferket, Peter; Linhart, Kirsten; Ho, Caroline; Novoselova, Tatiana V; Garg, Sumedha; Ridderstrale, Martin; Marcus,Science (New York, N.Y.)2013 Jul 19275-823869016
Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism.Ivanisevic, Julijana; Zhu, Zheng-Jiang; Plate, Lars; Tautenhahn, Ralf; Chen, Stephen; O'Brien, Peter J; Johnson, Caroline H; Marletta, Michael A; Patti, Gary J; Siuzdak, GaryAnalytical chemistry2013 Jul 166876-8423781873
MS/MS networking guided analysis of molecule and gene cluster families.Nguyen, Don Duy; Wu, Cheng-Hsuan; Moree, Wilna J; Lamsa, Anne; Medema, Marnix H; Zhao, Xiling; Gavilan, Ronnie G; Aparicio, Marystella; Atencio, Librada; Jackson, Chanaye; Ballesteros, Javier; Sanchez, Joel; Watrous, Jeramie D; Phelan, Vanessa V; van de WProceedings of the National Academy of Sciences of the United States of America2013 Jul 9E2611-2023798442
HR-MAS NMR Tissue Metabolomic Signatures Cross-validated by Mass Spectrometry Distinguish Bladder Cancer from Benign Disease.Tripathi, Pratima; Somashekar, Bagganahalli S; Ponnusamy, M; Gursky, Amy; Dailey, Stephen; Kunju, Priya; Lee, Cheryl T; Chinnaiyan, Arul M; Rajendiran, Thekkelnaycke M; Ramamoorthy, AyyalusamyJournal of proteome research2013 Jul 53519-2823731241
X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic ýý-Cell Function.Akiyama, Masaru; Liew, Chong Wee; Lu, Shusheng; Hu, Jiang; Martinez, Rachael; Hambro, Ben; Kennedy, Robert T; Kulkarni, Rohit NDiabetes2013 Jul2439-4923493568
Obesity-induced diabetes and lower urinary tract fibrosis promote urinary voiding dysfunction in a mouse model.Gharaee-Kermani, Mehrnaz; Rodriguez-Nieves, Jose A; Mehra, Rohit; Vezina, Chad A; Sarma, Aruna V; Macoska, Jill AThe Prostate2013 Jul1123-3323532836
Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle.Althagafy, Hanan S; Graf, Tyler N; Sy-Cordero, Arlene A; Gufford, Brandon T; Paine, Mary F; Wagoner, Jessica; Polyak, Stephen J; Croatt, Mitchell P; Oberlies, Nicholas HBioorganic & medicinal chemistry2013 Jul 13919-2623673225
Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Dong, Hua; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2013 Jul19-2923694766
Coordinate expression of transcripts and proteins in platelets.Rowley, Jesse W; Weyrich, Andrew SBlood2013 Jun 275255-623813941
Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.McDonnell, Scott R P; Hwang, Steven R; Rolland, Delphine; Murga-Zamalloa, Carlos; Basrur, Venkatesha; Conlon, Kevin P; Fermin, Damian; Wolfe, Thomas; Raskind, Alexander; Ruan, Chunhai; Jiang, Jian-Kang; Thomas, Craig J; Hogaboam, Cory M; Burant, Charles FBlood2013 Jun 27NULL23814019
Bacteriophage adhering to mucus provide a non-host-derived immunity.Barr, Jeremy J; Auro, Rita; Furlan, Mike; Whiteson, Katrine L; Erb, Marcella L; Pogliano, Joe; Stotland, Aleksandr; Wolkowicz, Roland; Cutting, Andrew S; Doran, Kelly S; Salamon, Peter; Youle, Merry; Rohwer, ForestProceedings of the National Academy of Sciences of the United States of America2013 Jun 2510771-623690590
Role of environmental and antibiotic stress on Staphylococcus epidermidis biofilm microstructure.Stewart, Elizabeth J; Satorius, Ashley E; Younger, John G; Solomon, Michael JLangmuir : the ACS journal of surfaces and colloids2013 Jun 117017-2423688391
ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.Essien, Bryan E; Grasberger, Helmut; Romain, Rachael D; Law, David J; Veniaminova, Natalia A; Saqui-Salces, Milena; El-Zaatari, Mohamad; Tessier, Arthur; Hayes, Michael M; Yang, Alexander C; Merchant, Juanita LGastroenterology2013 Jun1466-77, 1477.e1-923395646
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.Monda, Keri L; Chen, Gary K; Taylor, Kira C; Palmer, Cameron; Edwards, Todd L; Lange, Leslie A; Ng, Maggie C Y; Adeyemo, Adebowale A; Allison, Matthew A; Bielak, Lawrence F; Chen, Guanjie; Graff, Mariaelisa; Irvin, Marguerite R; Rhie, Suhn K; Li, Guo; LiuNature genetics2013 Jun690-623583978
Optimization of harvesting, extraction, and analytical protocols for UPLC-ESI-MS-based metabolomic analysis of adherent mammalian cancer cells.Bi, Huichang; Krausz, Kristopher W; Manna, Soumen K; Li, Fei; Johnson, Caroline H; Gonzalez, Frank JAnalytical and bioanalytical chemistry2013 Jun5279-8923604415
Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance.Liston, Conor; Cichon, Joseph M; Jeanneteau, Freddy; Jia, Zhengping; Chao, Moses V; Gan, Wen-BiaoNature neuroscience2013 Jun698-70523624512
Invited commentary: Quantifying salt in urine--a complex solution.de Boer, Ian H; Kestenbaum, BryanAmerican journal of epidemiology2013 Jun 11193-5; discussion 1196-823673248
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS genetics2013 June100350023754948
Mass spectrometry theory and application to adrenal diseases.Wooding, Kerry M; Auchus, Richard JMolecular and cellular endocrinology2013 May 22201-723333773
Anti-inflammatory Effects of Omega-3 Polyunsaturated Fatty Acids and Soluble Epoxide Hydrolase Inhibitors in Angiotensin-II Dependent Hypertension.Ulu, Arzu; Harris, Todd R; Morisseau, Christophe; Miyabe, Christina; Inoue, Hiromi; Schuster, Gertrud; Dong, Hua; Iosif, Ana-Maria; Liu, Jun-Yan; Weiss, Robert H; Chiamvimonvat, Nipavan; Imig, John D; Hammock, Bruce DJournal of cardiovascular pharmacology2013 May 14NULL23676336
Molar mass, entanglement, and associations of the biofilm polysaccharide of Staphylococcus epidermidis.Ganesan, Mahesh; Stewart, Elizabeth J; Szafranski, Jacob; Satorius, Ashley E; Younger, John G; Solomon, Michael JBiomacromolecules2013 May 131474-8123540609
Developmental programming: impact of prenatal testosterone excess on insulin sensitivity, adiposity, and free fatty acid profile in postpubertal female sheep.Veiga-Lopez, A; Moeller, J; Patel, D; Ye, W; Pease, A; Kinns, J; Padmanabhan, VEndocrinology2013 May1731-4223525243
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature genetics2013 May501-1223563607
Application of combined omics platforms to accelerate biomedical discovery in diabesity.Kurland, Irwin J; Accili, Domenico; Burant, Charles; Fischer, Steven M; Kahn, Barbara B; Newgard, Christopher B; Ramagiri, Suma; Ronnett, Gabriele V; Ryals, John A; Sanders, Mark; Shambaugh, Joe; Shockcor, John; Gross, Steven SAnnals of the New York Academy of Sciences2013 May16-Jan23659636
Epigenetics in hematology: introducing a collection of reviews.Goodell, Margaret ABlood2013 Apr 183059-6023599256
Metabolome response to glucose in the ýý-cell line INS-1 832/13.Lorenz, Matthew A; El Azzouny, Mahmoud A; Kennedy, Robert T; Burant, Charles FThe Journal of biological chemistry2013 Apr 1210923-3523426361
Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages.Rubinow, Katya B; Wall, Valerie Z; Nelson, Joel; Mar, Daniel; Bomsztyk, Karol; Askari, Bardia; Lai, Marvin A; Smith, Kelly D; Han, Myoung Sook; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Albert, Carolyn J; Ford, David A; Davis, Roger J; BornfeldThe Journal of biological chemistry2013 Apr 59957-7023426369
HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case.Napolitano, Jose G; Lankin, David C; Graf, Tyler N; Friesen, J Brent; Chen, Shao-Nong; McAlpine, James B; Oberlies, Nicholas H; Pauli, Guido FThe Journal of organic chemistry2013 Apr 52827-3923461697
Microbial metabolic exchange in 3D.Watrous, Jeramie D; Phelan, Vanessa V; Hsu, Cheng-Chih; Moree, Wilna J; Duggan, Brendan M; Alexandrov, Theodore; Dorrestein, Pieter CThe ISME journal2013 Apr770-8023283018
Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course.Anderson, Olivia S; Peterson, Karen E; Sanchez, Brisa N; Zhang, Zhenzhen; Mancuso, Peter; Dolinoy, Dana CFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013 Apr1784-9223345456
Complement c5a generation by staphylococcal biofilms.Satorius, Ashley E; Szafranski, Jacob; Pyne, Derek; Ganesan, Mahesh; Solomon, Michael J; Newton, Duane W; Bortz, David M; Younger, John GShock (Augusta, Ga.)2013 Apr336-4223459111
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.Dong, Chenfang; Yuan, Tingting; Wu, Yadi; Wang, Yifan; Fan, Teresa W M; Miriyala, Sumitra; Lin, Yiwei; Yao, Jun; Shi, Jian; Kang, Tiebang; Lorkiewicz, Pawel; St Clair, Daret; Hung, Mien-Chie; Evers, B Mark; Zhou, Binhua PCancer cell2013 Mar 18316-3123453623
Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection.Polyak, Stephen J; Ferenci, Peter; Pawlotsky, Jean-MichelHepatology (Baltimore, Md.)2013 Mar1262-7123213025
Age-dependent actions of dopamine on inhibitory synaptic transmission in superficial layers of mouse prefrontal cortex.Paul, Kush; Cox, Charles LJournal of neurophysiology2013 Mar1323-3223221420
Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response.Baik, Jason; Stringer, Kathleen A; Mane, Gerta; Rosania, Gus RAntimicrobial agents and chemotherapy2013 Mar1218-3023263006
Network motifs provide signatures that characterize metabolism.Shellman, Erin R; Burant, Charles F; Schnell, SantiagoMolecular bioSystems2013 Mar352-6023287894
Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.Li, Fei; Pang, Xiaoyan; Krausz, Kristopher W; Jiang, Changtao; Chen, Chi; Cook, John A; Krishna, Murali C; Mitchell, James B; Gonzalez, Frank J; Patterson, Andrew DJournal of proteome research2013 Mar 11369-7623301521
Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B.Esser-Nobis, Katharina; Romero-Brey, Ines; Ganten, Tom M; Gouttenoire, Jerome; Harak, Christian; Klein, Rahel; Schemmer, Peter; Binder, Marco; Schnitzler, Paul; Moradpour, Darius; Bartenschlager, Ralf; Polyak, Stephen J; Stremmel, Wolfgang; Penin, FrancoiHepatology (Baltimore, Md.)2013 Mar953-6323322644
Role of pulmonary artery reactivity and nitric oxide in injury and inflammation following lung contusion.Lakshminrusimha, Satyan; Suresh, Madathilparambil V; Knight, Paul R; Gugino, Sylvia F; Davidson, Bruce A; Helinski, Jadwiga D; Nielsen, Lori C; Russell, James A; Yu, Bi; Zeng, Lixia; Pennathur, Subramaniam; Raghavendran, KrishnanShock (Augusta, Ga.)2013 Mar278-8523364426
Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database.Zhu, Zheng-Jiang; Schultz, Andrew W; Wang, Junhua; Johnson, Caroline H; Yannone, Steven M; Patti, Gary J; Siuzdak, GaryNature protocols2013 Mar451-6023391889
Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.Kahle, Juliette J; Souroullas, George P; Yu, Peng; Zohren, Fabian; Lee, Yoontae; Shaw, Chad A; Zoghbi, Huda Y; Goodell, Margaret APLoS genetics2013 Mare100335923555280
Dampened dopamine-mediated neuromodulation in prefrontal cortex of fragile X mice.Paul, Kush; Venkitaramani, Deepa V; Cox, Charles LThe Journal of physiology2013 Feb 151133-4323148316
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.Gautier, Emmanuel L; Westerterp, Marit; Bhagwat, Neha; Cremers, Serge; Shih, Alan; Abdel-Wahab, Omar; Lutjohann, Dieter; Randolph, Gwendalyn J; Levine, Ross L; Tall, Alan R; Yvan-Charvet, LaurentThe Journal of experimental medicine2013 Feb 11339-5323319699
Paricalcitol does not improve glucose metabolism in patients with stage 3-4 chronic kidney disease.de Boer, Ian H; Sachs, Michael; Hoofnagle, Andrew N; Utzschneider, Kristina M; Kahn, Steven E; Kestenbaum, Bryan; Himmelfarb, JonathanKidney international2013 Feb323-3022913981
Cystic fibrosis therapy: a community ecology perspective.Conrad, Douglas; Haynes, Matthew; Salamon, Peter; Rainey, Paul B; Youle, Merry; Rohwer, ForestAmerican journal of respiratory cell and molecular biology2013 Feb150-623103995
Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha.Montanez, Jessica E; Peters, Jeffrey M; Correll, Jared B; Gonzalez, Frank J; Patterson, Andrew DToxicologic pathology2013 Feb410-823197196
Enhanced bioactivity of silybin B methylation products.Sy-Cordero, Arlene A; Graf, Tyler N; Runyon, Scott P; Wani, Mansukh C; Kroll, David J; Agarwal, Rajesh; Brantley, Scott J; Paine, Mary F; Polyak, Stephen J; Oberlies, Nicholas HBioorganic & medicinal chemistry2013 Feb 1742-723260576
Kidney disease and increased mortality risk in type 2 diabetes.Afkarian, Maryam; Sachs, Michael C; Kestenbaum, Bryan; Hirsch, Irl B; Tuttle, Katherine R; Himmelfarb, Jonathan; de Boer, Ian HJournal of the American Society of Nephrology : JASN2013 Feb302-823362314
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.Vivekanandan-Giri, Anuradha; Slocum, Jessica L; Byun, Jaeman; Tang, Chongren; Sands, Robin L; Gillespie, Brenda W; Heinecke, Jay W; Saran, Rajiv; Kaplan, Mariana J; Pennathur, SubramaniamAnnals of the rheumatic diseases2013 Jan 12NULL23313808
Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation.Ong, Kuok Teong; Mashek, Mara T; Bu, So Young; Mashek, Douglas GFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013 Jan313-2122993196
Silymarin for HCV infection.Polyak, Stephen J; Oberlies, Nicholas H; Pecheur, Eve-Isabelle; Dahari, Harel; Ferenci, Peter; Pawlotsky, Jean-MichelAntiviral therapy2013141-723011959
Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors.Rossi, Lara; Lemoli, Roberto M; Goodell, Margaret AExperimental hematology2013 Jan102-1223022127
Isolation and characterization of mouse side population cells.Ergen, Aysegul V; Jeong, Mira; Lin, Kuanyin K; Challen, Grant A; Goodell, Margaret AMethods in molecular biology (Clifton, N.J.)2013151-6223179831
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.Horikoshi, Momoko; Yaghootkar, Hanieh; Mook-Kanamori, Dennis O; Sovio, Ulla; Taal, H Rob; Hennig, Branwen J; Bradfield, Jonathan P; St Pourcain, Beate; Evans, David M; Charoen, Pimphen; Kaakinen, Marika; Cousminer, Diana L; Lehtimaki, Terho; Kreiner-MolleNature genetics2013 Jan76-8223202124
Spatiotemporal dynamics of complement C5a production within bacterial extracellular polymeric substance.Conrad, Erin C; Hsu, Yueh-Ya; Bortz, David M; Younger, John GJournal of innate immunity2013114-2323328643
Mini-review: Lactoferrin: a bioinspired, anti-biofilm therapeutic.Ammons, M C; Copie, VBiofouling2013443-5523574002
Error Analysis and Propagation in Metabolomics Data Analysis.Moseley, Hunter N BComputational and structural biotechnology journal2013 Jan 123667718
Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung, based on a genome reconstructed from metagenomic data.Lim, Yan Wei; Schmieder, Robert; Haynes, Matthew; Furlan, Mike; Matthews, T David; Whiteson, Katrine; Poole, Stephen J; Hayes, Christopher S; Low, David A; Maughan, Heather; Edwards, Robert; Conrad, Douglas; Rohwer, ForestPloS one2013e6428523737977
Pharmacometabolomic signature of ataxia SCA1 mouse model and lithium effects.Perroud, Bertrand; Jafar-Nejad, Paymaan; Wikoff, William R; Gatchel, Jennifer R; Wang, Lu; Barupal, Dinesh K; Crespo-Barreto, Juan; Fiehn, Oliver; Zoghbi, Huda Y; Kaddurah-Daouk, RimaPloS one2013e7061023936457
Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids.Nording, Malin L; Yang, Jun; Georgi, Katrin; Hegedus Karbowski, Christine; German, J Bruce; Weiss, Robert H; Hogg, Ronald J; Trygg, Johan; Hammock, Bruce D; Zivkovic, Angela MPloS one2013e7657524204640
Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung.Yang, Jun; Solaimani, Parrisa; Dong, Hua; Hammock, Bruce; Hankinson, OliverThe Journal of toxicological sciences2013833-624213002
A prospective study of frailty in nephrology-referred patients with CKD.Roshanravan, Baback; Khatri, Minesh; Robinson-Cohen, Cassianne; Levin, Greg; Patel, Kushang V; de Boer, Ian H; Seliger, Stephen; Ruzinski, John; Himmelfarb, Jonathan; Kestenbaum, BryanAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2012 Dec912-2122770927
Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height.Lui, Julian C; Nilsson, Ola; Chan, Yingleong; Palmer, Cameron D; Andrade, Anenisia C; Hirschhorn, Joel N; Baron, JeffreyHuman molecular genetics2012 Dec 15193-20122914739
Absolute Configuration of Isosilybin A by X-ray Crystallography of the Heavy Atom Analogue 7-(4-Bromobenzoyl)isosilybin A.Sy-Cordero, Arlene A; Day, Cynthia S; Oberlies, Nicholas HJournal of natural products2012 Nov 1NULL23116206
Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 ýý.McInturff, Alison M; Cody, Mark J; Elliott, Elizabeth A; Glenn, Jared W; Rowley, Jesse W; Rondina, Matthew T; Yost, Christian CBlood2012 Oct 113118-2522919032
FTO genotype is associated with phenotypic variability of body mass index.Yang, Jian; Loos, Ruth J F; Powell, Joseph E; Medland, Sarah E; Speliotes, Elizabeth K; Chasman, Daniel I; Rose, Lynda M; Thorleifsson, Gudmar; Steinthorsdottir, Valgerdur; Magi, Reedik; Waite, Lindsay; Smith, Albert Vernon; Yerges-Armstrong, Laura M; MonNature2012 Oct 11267-7222982992
Activity-dependent regulation of retinogeniculate signaling by metabotropic glutamate receptors.Govindaiah, Gubbi; Wang, Tongfei; Gillette, Martha U; Cox, Charles LThe Journal of neuroscience : the official journal of the Society for Neuroscience2012 Sep 1212820-3122973005
Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.Rossi, Lara; Lin, Kuanyin K; Boles, Nathan C; Yang, Liubin; King, Katherine Y; Jeong, Mira; Mayle, Allison; Goodell, Margaret ACell stem cell2012 Sep 7302-1722958929
The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease.Bosworth, Cortney R; Levin, Gregory; Robinson-Cohen, Cassianne; Hoofnagle, Andrew N; Ruzinski, John; Young, Bessie; Schwartz, Stephen M; Himmelfarb, Jonathan; Kestenbaum, Bryan; de Boer, Ian HKidney international2012 Sep693-70022648296
Platelet mRNA: the meaning behind the message.Rowley, Jesse W; Schwertz, Hansjorg; Weyrich, Andrew SCurrent opinion in hematology2012 Sep385-9122814651
Going viral: next-generation sequencing applied to phage populations in the human gut.Reyes, Alejandro; Semenkovich, Nicholas P; Whiteson, Katrine; Rohwer, Forest; Gordon, Jeffrey INature reviews. Microbiology2012 Sep607-1722864264
Evidence of widespread selection on standing variation in Europe at height-associated SNPs.Turchin, Michael C; Chiang, Charleston W K; Palmer, Cameron D; Sankararaman, Sriram; Reich, David; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Hirschhorn, Joel NNature genetics2012 Sep1015-922902787
Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities.Lim, Yan Wei; Schmieder, Robert; Haynes, Matthew; Willner, Dana; Furlan, Mike; Youle, Merry; Abbott, Katelynn; Edwards, Robert; Evangelista, Jose; Conrad, Douglas; Rohwer, ForestJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2012 Aug 28NULL22951208
Multicellularity and antibiotic resistance in Klebsiella pneumoniae grown under bloodstream-mimicking fluid dynamic conditions.Thornton, Margaret M; Chung-Esaki, Hangyul M; Irvin, Charlene B; Bortz, David M; Solomon, Michael J; Younger, John GThe Journal of infectious diseases2012 Aug 15588-9522711903
The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.Zohren, Fabian; Souroullas, George P; Luo, Min; Gerdemann, Ulrike; Imperato, Maria R; Wilson, Nicola K; Gottgens, Berthold; Lukov, Georgi L; Goodell, Margaret ANature immunology2012 Aug761-922772404
The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool.James, Regis A; Rao, Mitchell M; Chen, Edward S; Goodell, Margaret A; Shaw, Chad ABioinformatics (Oxford, England)2012 Jul 151941-222576171
Insulin resistance, cystatin C, and mortality among older adults.de Boer, Ian H; Katz, Ronit; Chonchol, Michel B; Fried, Linda F; Ix, Joachim H; Kestenbaum, Bryan; Mukamal, Kenneth J; Peralta, Carmen A; Siscovick, David SDiabetes care2012 Jun1355-6022432118
Cicatricial Alopecia Symposium 2011: Lipids, inflammation and stem cells.Karnik, Pratima; Stenn, KurtThe Journal of investigative dermatology2012 Jun1529-3122584498
Calcium, magnesium, and colorectal cancer.Dai, Qi; Sandler, Robert; Barry, Elizabeth; Summers, Robert; Grau, Maria; Baron, JohnEpidemiology (Cambridge, Mass.)2012 May504-522475836
A genome-wide association meta-analysis identifies new childhood obesity loci.Bradfield, Jonathan P; Taal, H Rob; Timpson, Nicholas J; Scherag, Andre; Lecoeur, Cecile; Warrington, Nicole M; Hypponen, Elina; Holst, Claus; Valcarcel, Beatriz; Thiering, Elisabeth; Salem, Rany M; Schumacher, Fredrick R; Cousminer, Diana L; Sleiman, PatNature genetics2012 May526-3122484627
Chronic kidney disease, insulin resistance, and incident diabetes in older adults.Pham, Hien; Robinson-Cohen, Cassianne; Biggs, Mary L; Ix, Joachim H; Mukamal, Kenneth J; Fried, Linda F; Kestenbaum, Bryan; Siscovick, David S; de Boer, Ian HClinical journal of the American Society of Nephrology : CJASN2012 Apr588-9422383749
Gencrypt: one-way cryptographic hashes to detect overlapping individuals across samples.Turchin, Michael C; Hirschhorn, Joel NBioinformatics (Oxford, England)2012 Mar 15886-822302573
Spatial distribution of microbial communities in the cystic fibrosis lung.Willner, Dana; Haynes, Matthew R; Furlan, Mike; Schmieder, Robert; Lim, Yan Wei; Rainey, Paul B; Rohwer, Forest; Conrad, DouglasThe ISME journal2012 Feb471-421796216
Case studies of the spatial heterogeneity of DNA viruses in the cystic fibrosis lung.Willner, Dana; Haynes, Matthew R; Furlan, Mike; Hanson, Nicole; Kirby, Breeann; Lim, Yan Wei; Rainey, Paul B; Schmieder, Robert; Youle, Merry; Conrad, Douglas; Rohwer, ForestAmerican journal of respiratory cell and molecular biology2012 Feb127-3121980056
A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses.Polyak, Stephen J; Morishima, Chihiro; Scott, John D; Gastaminza, Pablo; Cox, Andrea; de Araujo, Evaldo Stanislau Affonso; Higgs, Martin R; Loo, Yueh-Ming; Golden-Mason, Lucy; Lindenbach, Brett D; Baumert, Thomas F; Randall, Glenn; Gale Jr, MichaelGastroenterology2012 Jane1-522185796
Genome-wide association and functional follow-up reveals new loci for kidney function.Pattaro, Cristian; Kottgen, Anna; Teumer, Alexander; Garnaas, Maija; Boger, Carsten A; Fuchsberger, Christian; Olden, Matthias; Chen, Ming-Huei; Tin, Adrienne; Taliun, Daniel; Li, Man; Gao, Xiaoyi; Gorski, Mathias; Yang, Qiong; Hundertmark, Claudia; FostePLoS genetics2012e100258422479191
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS genetics2012e100260722479202
Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia.Panicker, Sreejith P; Ganguly, Taneeta; Consolo, Mary; Price, Vera; Mirmirani, Paradi; Honda, Kord; Karnik, PratimaPloS one2012e3844922685570
Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation.McClure, Janela; Lovelace, Erica S; Elahi, Shokrollah; Maurice, Nicholas J; Wagoner, Jessica; Dragavon, Joan; Mittler, John E; Kraft, Zane; Stamatatos, Leonidis; Horton, Helen; De Rosa, Stephen C; Coombs, Robert W; Polyak, Stephen JPloS one2012e4183222848626
Mucus distribution model in a lung with cystic fibrosis.Zarei, Sara; Mirtar, Ali; Rohwer, Forest; Conrad, Douglas J; Theilmann, Rebecca J; Salamon, PeterComputational and mathematical methods in medicine201297080923118803
Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes.DCCT/EDIC Research Group; de Boer, Ian H; Sun, Wanjie; Cleary, Patricia A; Lachin, John M; Molitch, Mark E; Steffes, Michael W; Zinman, BernardThe New England journal of medicine2011 Dec 222366-7622077236
Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.Chan, Yingleong; Holmen, Oddgeir L; Dauber, Andrew; Vatten, Lars; Havulinna, Aki S; Skorpen, Frank; Kvaloy, Kirsti; Silander, Kaisa; Nguyen, Thutrang T; Willer, Cristen; Boehnke, Michael; Perola, Markus; Palotie, Aarno; Salomaa, Veikko; Hveem, Kristian; FPLoS genetics2011 Dece100243922242009
The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA.Chiang, Charleston W K; Gajdos, Zofia K Z; Korn, Joshua M; Butler, Johannah L; Hackett, Rachel; Guiducci, Candace; Nguyen, Thutrang T; Wilks, Rainford; Forrester, Terrence; Henderson, Katherine D; Le Marchand, Loic; Henderson, Brian E; Haiman, ChristopherHuman genetics2011 Nov607-2121424828
Measurement of insulin resistance in chronic kidney disease.Pham, Hien; Utzschneider, Kristina M; de Boer, Ian HCurrent opinion in nephrology and hypertension2011 Nov640-621885970
Optimizing patient safety during hemodialysis.Himmelfarb, JonathanJAMA : the journal of the American Medical Association2011 Oct 191707-822009104
Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling.Coleman, Rosalind A; Mashek, Douglas GChemical reviews2011 Oct 126359-8621627334
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature2011 Oct 6103-921909115
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.N'Diaye, Amidou; Chen, Gary K; Palmer, Cameron D; Ge, Bing; Tayo, Bamidele; Mathias, Rasika A; Ding, Jingzhong; Nalls, Michael A; Adeyemo, Adebowale; Adoue, Veronique; Ambrosone, Christine B; Atwood, Larry; Bandera, Elisa V; Becker, Lewis C; Berndt, SonjaPLoS genetics2011 Octe100229821998595
Serum 25-hydroxyvitamin D and change in estimated glomerular filtration rate.de Boer, Ian H; Katz, Ronit; Chonchol, Michel; Ix, Joachim H; Sarnak, Mark J; Shlipak, Michael G; Siscovick, David S; Kestenbaum, BryanClinical journal of the American Society of Nephrology : CJASN2011 Sep2141-921836148
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.Boger, Carsten A; Gorski, Mathias; Li, Man; Hoffmann, Michael M; Huang, Chunmei; Yang, Qiong; Teumer, Alexander; Krane, Vera; O'Seaghdha, Conall M; Kutalik, Zoltan; Wichmann, H-Erich; Haak, Thomas; Boes, Eva; Coassin, Stefan; Coresh, Josef; Kollerits, BarPLoS genetics2011 Sepe100229221980298
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.Kilpelainen, Tuomas O; Zillikens, M Carola; Stancakova, Alena; Finucane, Francis M; Ried, Janina S; Langenberg, Claudia; Zhang, Weihua; Beckmann, Jacques S; Luan, Jian'an; Vandenput, Liesbeth; Styrkarsdottir, Unnur; Zhou, Yanhua; Smith, Albert Vernon; ZhaNature genetics2011 Aug753-6021706003
Temporal trends in the prevalence of diabetic kidney disease in the United States.de Boer, Ian H; Rue, Tessa C; Hall, Yoshio N; Heagerty, Patrick J; Weiss, Noel S; Himmelfarb, JonathanJAMA : the journal of the American Medical Association2011 Jun 222532-921693741
Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.Del Greco M, Fabiola; Pattaro, Cristian; Luchner, Andreas; Pichler, Irene; Winkler, Thomas; Hicks, Andrew A; Fuchsberger, Christian; Franke, Andre; Melville, Scott A; Peters, Annette; Wichmann, H Erich; Schreiber, Stefan; Heid, Iris M; Krawczak, Michael; Human molecular genetics2011 Apr 151660-7121273288
Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort.de Boer, Ian H; Rue, Tessa C; Cleary, Patricia A; Lachin, John M; Molitch, Mark E; Steffes, Michael W; Sun, Wanjie; Zinman, Bernard; Brunzell, John D; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Archives of internal medicine2011 Mar 14412-2021403038
CUBN is a gene locus for albuminuria.Boger, Carsten A; Chen, Ming-Huei; Tin, Adrienne; Olden, Matthias; Kottgen, Anna; de Boer, Ian H; Fuchsberger, Christian; O'Seaghdha, Conall M; Pattaro, Cristian; Teumer, Alexander; Liu, Ching-Ti; Glazer, Nicole L; Li, Man; O'Connell, Jeffrey R; Tanaka, TJournal of the American Society of Nephrology : JASN2011 Mar555-7021355061
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.Speliotes, Elizabeth K; Yerges-Armstrong, Laura M; Wu, Jun; Hernaez, Ruben; Kim, Lauren J; Palmer, Cameron D; Gudnason, Vilmundur; Eiriksdottir, Gudny; Garcia, Melissa E; Launer, Lenore J; Nalls, Michael A; Clark, Jeanne M; Mitchell, Braxton D; Shuldiner,PLoS genetics2011 Mare100132421423719
First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.Holzapfel, Christina; Grallert, Harald; Baumert, Jens; Thorand, Barbara; Doring, Angela; Wichmann, H Erich; Hauner, Hans; Illig, Thomas; Mielck, AndreasJournal of epidemiology and community health2011 Feb174-620628085
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning.Ong, Kuok Teong; Mashek, Mara T; Bu, So Young; Greenberg, Andrew S; Mashek, Douglas GHepatology (Baltimore, Md.)2011 Jan116-2620967758
Hematopoietic stem cell characterization and isolation.Rossi, Lara; Challen, Grant A; Sirin, Olga; Lin, Karen Kuan-Yin; Goodell, Margaret AMethods in molecular biology (Clifton, N.J.)201147-5921618082
Detection of hematopoietic stem cells by flow cytometry.Lin, Kuanyin K; Goodell, Magaret AMethods in cell biology201121-3021722798
Dynamics of human complement-mediated killing of Klebsiella pneumoniae.Nypaver, Christina M; Thornton, Margaret M; Yin, Suellen M; Bracho, David O; Nelson, Patrick W; Jones, Alan E; Bortz, David M; Younger, John GAmerican journal of respiratory cell and molecular biology2010 Nov585-9020008281
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature genetics2010 Nov949-6020935629
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature genetics2010 Nov937-4820935630
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature2010 Oct 14832-820881960
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome.Pan, Feng; Aldridge, Georgina M; Greenough, William T; Gan, Wen-BiaoProceedings of the National Academy of Sciences of the United States of America2010 Oct 1217768-7320861447
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.Holzapfel, C; Grallert, H; Huth, C; Wahl, S; Fischer, B; Doring, A; Ruckert, I M; Hinney, A; Hebebrand, J; Wichmann, H-E; Hauner, H; Illig, T; Heid, I MInternational journal of obesity (2005)2010 Oct1538-4520386550
PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.Speliotes, Elizabeth K; Butler, Johannah L; Palmer, Cameron D; Voight, Benjamin F; GIANT Consortium; MIGen Consortium; NASH CRN; Hirschhorn, Joel NHepatology (Baltimore, Md.)2010 Sep904-1220648472
Fine mapping of the association with obesity at the FTO locus in African-derived populations.Hassanein, Mohamed T; Lyon, Helen N; Nguyen, Thutrang T; Akylbekova, Ermeg L; Waters, Kevin; Lettre, Guillaume; Tayo, Bamidele; Forrester, Terrence; Sarpong, Daniel F; Stram, Dan O; Butler, Johannah L; Wilks, Rainford; Liu, Jiankang; Le Marchand, Loic; KoHuman molecular genetics2010 Jul 152907-1620430937
Genome-wide association of anthropometric traits in African- and African-derived populations.Kang, Sun J; Chiang, Charleston W K; Palmer, Cameron D; Tayo, Bamidele O; Lettre, Guillaume; Butler, Johannah L; Hackett, Rachel; Adeyemo, Adebowale A; Guiducci, Candace; Berzins, Ilze; Nguyen, Thutrang T; Feng, Tao; Luke, Amy; Shriner, Daniel; Ardlie, KrHuman molecular genetics2010 Jul 12725-3820400458
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.Freathy, Rachel M; Mook-Kanamori, Dennis O; Sovio, Ulla; Prokopenko, Inga; Timpson, Nicholas J; Berry, Diane J; Warrington, Nicole M; Widen, Elisabeth; Hottenga, Jouke Jan; Kaakinen, Marika; Lange, Leslie A; Bradfield, Jonathan P; Kerkhof, Marjan; Marsh, Nature genetics2010 May430-520372150
New loci associated with kidney function and chronic kidney disease.Kottgen, Anna; Pattaro, Cristian; Boger, Carsten A; Fuchsberger, Christian; Olden, Matthias; Glazer, Nicole L; Parsa, Afshin; Gao, Xiaoyi; Yang, Qiong; Smith, Albert V; O'Connell, Jeffrey R; Li, Man; Schmidt, Helena; Tanaka, Toshiko; Isaacs, Aaron; KetkarNature genetics2010 May376-8420383146
Lipids to the top of hair biology.Stenn, Kurt S; Karnik, PratimaThe Journal of investigative dermatology2010 May1205-720393475
Complement activation in emergency department patients with severe sepsis.Younger, John G; Bracho, David O; Chung-Esaki, Hangyul M; Lee, Moonseok; Rana, Gurpreet K; Sen, Ananda; Jones, Alan EAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2010 Apr353-920370773
Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples.Chiang, Charleston W K; Gajdos, Zofia K Z; Korn, Joshua M; Kuruvilla, Finny G; Butler, Johannah L; Hackett, Rachel; Guiducci, Candace; Nguyen, Thutrang T; Wilks, Rainford; Forrester, Terrence; Haiman, Christopher A; Henderson, Katherine D; Le Marchand, LoPLoS genetics2010 Mare100086620221249
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.Heid, Iris M; Henneman, Peter; Hicks, Andrew; Coassin, Stefan; Winkler, Thomas; Aulchenko, Yurii S; Fuchsberger, Christian; Song, Kijoung; Hivert, Marie-France; Waterworth, Dawn M; Timpson, Nicholas J; Richards, J Brent; Perry, John R B; Tanaka, Toshiko; Atherosclerosis2010 Feb412-2020018283
Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist.Mirmirani, Paradi; Karnik, PratimaArchives of dermatology2009 Dec1363-620026843
Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?Heid, Iris M; Huth, Cornelia; Loos, Ruth J F; Kronenberg, Florian; Adamkova, Vera; Anand, Sonia S; Ardlie, Kristin; Biebermann, Heike; Bjerregaard, Peter; Boeing, Heiner; Bouchard, Claude; Ciullo, Marina; Cooper, Jackie A; Corella, Dolores; Dina, ChristiaPLoS genetics2009 Octe100069419851442
Flexible microfluidic device for mechanical property characterization of soft viscoelastic solids such as bacterial biofilms.Hohne, Danial N; Younger, John G; Solomon, Michael JLangmuir : the ACS journal of surfaces and colloids2009 Jul 77743-5119219968
No association of two functional polymorphisms in human ALOX15 with myocardial infarction.Hersberger, Martin; Muller, Martina; Marti-Jaun, Jacqueline; Heid, Iris M; Coassin, Stefan; Young, Thomas F; Waechter, Vanessa; Hengstenberg, Christian; Meisinger, Christine; Peters, Annette; Konig, Wolfgang; Holmer, Stephan; Schunkert, Heribert; Klopp, NAtherosclerosis2009 Jul192-619131063
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.Lindgren, Cecilia M; Heid, Iris M; Randall, Joshua C; Lamina, Claudia; Steinthorsdottir, Valgerdur; Qi, Lu; Speliotes, Elizabeth K; Thorleifsson, Gudmar; Willer, Cristen J; Herrera, Blanca M; Jackson, Anne U; Lim, Noha; Scheet, Paul; Soranzo, Nicole; AminPLoS genetics2009 June100050819557161
Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia.Karnik, Pratima; Tekeste, Zenar; McCormick, Thomas S; Gilliam, Anita C; Price, Vera H; Cooper, Kevin D; Mirmirani, ParadiThe Journal of investigative dermatology2009 May1243-5719052558
Use of weighted reference panels based on empirical estimates of ancestry for capturing untyped variation.Egyud, Matthew R L; Gajdos, Zofia K Z; Butler, Johannah L; Tischfield, Sam; Le Marchand, Loic; Kolonel, Laurence N; Haiman, Christopher A; Henderson, Brian E; Hirschhorn, Joel NHuman genetics2009 Apr295-30319184111
Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.Boes, Eva; Coassin, Stefan; Kollerits, Barbara; Heid, Iris M; Kronenberg, FlorianExperimental gerontology2009 Mar136-6019041386
Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: observational follow-up of a randomized study.Grau, Maria V; Sandler, Robert S; McKeown-Eyssen, Gail; Bresalier, Robert S; Haile, Robert W; Barry, Elizabeth L; Ahnen, Dennis J; Gui, Jiang; Summers, Robert W; Baron, John AJournal of the National Cancer Institute2009 Feb 18267-7619211442
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.Willer, Cristen J; Speliotes, Elizabeth K; Loos, Ruth J F; Li, Shengxu; Lindgren, Cecilia M; Heid, Iris M; Berndt, Sonja I; Elliott, Amanda L; Jackson, Anne U; Lamina, Claudia; Lettre, Guillaume; Lim, Noha; Lyon, Helen N; McCarroll, Steven A; Papadakis, KNature genetics2009 Jan25-3419079261
Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.Singmann, Paula; Baumert, Jens; Herder, Christian; Meisinger, Christa; Holzapfel, Christina; Klopp, Norman; Wichmann, H-Erich; Klingenspor, Martin; Rathmann, Wolfgang; Illig, Thomas; Grallert, HaraldObesity facts2009235-4220054229
Dynamical system analysis of Staphylococcus epidermidis bloodstream infection.Chung, Hangyul M; Cartwright, Megan M; Bortz, David M; Jackson, Trachette L; Younger, John GShock (Augusta, Ga.)2008 Nov518-2618317411
Genome-wide association studies: implications for multiethnic samples.Cooper, Richard S; Tayo, Bamidele; Zhu, XiaofengHuman molecular genetics2008 Oct 15R151-518852204
Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons.Pichler, Michaela; Kollerits, Barbara; Heid, Iris M; Hunt, Steven C; Adams, Ted D; Hopkins, Paul N; Kronenberg, FlorianThe American journal of clinical nutrition2008 Sep797-80018779298
Identification of ten loci associated with height highlights new biological pathways in human growth.Lettre, Guillaume; Jackson, Anne U; Gieger, Christian; Schumacher, Fredrick R; Berndt, Sonja I; Sanna, Serena; Eyheramendy, Susana; Voight, Benjamin F; Butler, Johannah L; Guiducci, Candace; Illig, Thomas; Hackett, Rachel; Heid, Iris M; Jacobs, Kevin B; LNature genetics2008 May584-9118391950
Klebsiella pneumoniae flocculation dynamics.Bortz, D M; Jackson, T L; Taylor, K A; Thompson, A P; Younger, J GBulletin of mathematical biology2008 Apr745-6818071828
On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test.Ionita-Laza, Iuliana; Perry, George H; Raby, Benjamin A; Klanderman, Barbara; Lee, Charles; Laird, Nan M; Weiss, Scott T; Lange, ChristophGenetic epidemiology2008 Apr273-8418228561
Leptin improves pulmonary bacterial clearance and survival in ob/ob mice during pneumococcal pneumonia.Hsu, A; Aronoff, D M; Phipps, J; Goel, D; Mancuso, PClinical and experimental immunology2007 Nov332-917822444
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial.Grau, Maria V; Baron, John A; Sandler, Robert S; Wallace, Kristin; Haile, Robert W; Church, Timothy R; Beck, Gerald J; Summers, Robert W; Barry, Elizabeth L; Cole, Bernard F; Snover, Dale C; Rothstein, Richard; Mandel, Jack SJournal of the National Cancer Institute2007 Jan 17129-3617227996
Generation of C5a in the absence of C3: a new complement activation pathway.Huber-Lang, Markus; Sarma, J Vidya; Zetoune, Firas S; Rittirsch, Daniel; Neff, Thomas A; McGuire, Stephanie R; Lambris, John D; Warner, Roscoe L; Flierl, Michael A; Hoesel, Laszlo M; Gebhard, Florian; Younger, John G; Drouin, Scott M; Wetsel, Rick A; WardNature medicine2006 Jun682-716715088
Dynamics of intrapulmonary bacterial growth in a murine model of repeated microaspiration.Ben-David, Itzhak; Price, Sarah E; Bortz, David M; Greineder, Colin F; Cohen, Samuel E; Bauer, Amy L; Jackson, Trachette L; Younger, John GAmerican journal of respiratory cell and molecular biology2005 Nov476-8216014897
Complement C5 and early oxygen kinetics during murine sepsis.Valencia, Gabriel; Sarma, J Vidya; Younger, John GAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2005 Apr275-8115805316


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