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Metabolomics (232)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Hepatic 11*-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique.Dube, Simmi; Norby, Barbara; Pattan, Vishwanath; Lingineni, Ravi K; Singh, Ravinder J; Carter, Rickey E; Basu, Ananda; Basu, RitaDiabetologia2014 Jul1446-5524771091
mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).Rodgers, Joseph T; King, Katherine Y; Brett, Jamie O; Cromie, Melinda J; Charville, Gregory W; Maguire, Katie K; Brunson, Christopher; Mastey, Namrata; Liu, Ling; Tsai, Chang-Ru; Goodell, Margaret A; Rando, Thomas ANature2014 Jun 19393-624870234
Analysis of Human Serum and Whole Blood for Mineral Content by ICP-MS and ICP-OES: Development of a Mineralomics Method.Harrington, James M; Young, Daniel J; Essader, Amal S; Sumner, Susan J; Levine, Keith EBiological trace element research2014 Jun 11NULL24917052
Quantitative NMR Metabolite Profiling of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Discriminates between Biofilm and Planktonic Phenotypes.Ammons, Mary Cloud B; Tripet, Brian P; Carlson, Ross P; Kirker, Kelly R; Gross, Michael A; Stanisich, Jessica J; Copie, ValerieJournal of proteome research2014 Jun 62973-8524809402
MR microscopy of formalin fixed paraffin embedded histology specimens.Macura, Slobodan; Mishra, Prasanna K; Gamez, Jeffrey D; Pirko, IstvanMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine2014 Jun1989-9424715442
Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins.Schebb, Nils Helge; Ostermann, Annika I; Yang, Jun; Hammock, Bruce D; Hahn, Andreas; Schuchardt, Jan PhilippProstaglandins & other lipid mediators2014 May 29NULL24880049
Customized Metabolomics Database for the Analysis of NMR (1)H-(1)H TOCSY and (13)C-(1)H HSQC-TOCSY Spectra of Complex Mixtures.Bingol, Kerem; Bruschweiler-Li, Lei; Li, Da-Wei; Bruschweiler, RafaelAnalytical chemistry2014 May 20NULL24773139
Training Status Diverges Muscle Diacylglycerol Accumulation During Free Fatty Acid Elevation.Chow, Lisa S; Mashek, Douglas G; Austin, Erin; Eberly, Lynn E; Persson, Xuan-Mai; Mashek, Mara T; Seaquist, Elizabeth R; Jensen, Michael DAmerican journal of physiology. Endocrinology and metabolism2014 May 20NULL24844260
Improving Ion Mobility Measurement Sensitivity by Utilizing Helium in an Ion Funnel Trap.Ibrahim, Yehia M; Garimella, Sandilya V B; Tolmachev, Aleksey V; Baker, Erin S; Smith, Richard DAnalytical chemistry2014 May 13NULL24786390
Increased Glucose Metabolism and Glycerolipid Formation by Fatty Acids and GPR40 Receptor Signaling Underlies the Fatty Acid Potentiation of Insulin Secretion.El-Azzouny, Mahmoud; Evans, Charles R; Treutelaar, Mary K; Kennedy, Robert T; Burant, Charles FThe Journal of biological chemistry2014 May 913575-8824675078
A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.Lanning, Nathan J; Looyenga, Brendan D; Kauffman, Audra L; Niemi, Natalie M; Sudderth, Jessica; DeBerardinis, Ralph J; MacKeigan, Jeffrey PCell reports2014 May 8907-1724767988
Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.Xie, Han; Hanai, Jun-Ichi; Ren, Jian-Guo; Kats, Lev; Burgess, Kerri; Bhargava, Parul; Signoretti, Sabina; Billiard, Julia; Duffy, Kevin J; Grant, Aaron; Wang, Xiaoen; Lorkiewicz, Pawel K; Schatzman, Sabrina; Bousamra 2nd, Michael; Lane, Andrew N; Higashi,Cell metabolism2014 May 6795-80924726384
Detecting and Removing Data Artifacts in Hadamard Transform Ion Mobility-Mass Spectrometry Measurements.Prost, Spencer A; Crowell, Kevin L; Baker, Erin S; Ibrahim, Yehia M; Clowers, Brian H; Monroe, Matthew E; Anderson, Gordon A; Smith, Richard D; Payne, Samuel HJournal of the American Society for Mass Spectrometry2014 May 6NULL24796262
After the feature presentation: technologies bridging untargeted metabolomics and biology.Cho, Kevin; Mahieu, Nathaniel G; Johnson, Stephen L; Patti, Gary JCurrent opinion in biotechnology2014 May 5143-14824816495
Impact of a transposon insertion in phzF2 on the specialized metabolite production and interkingdom interactions of Pseudomonas aeruginosa.Phelan, Vanessa V; Moree, Wilna J; Aguilar, Julieta; Cornett, Dale S; Koumoutsi, Alexandra; Noble, Suzanne M; Pogliano, Kit; Guerrero, Carlos A; Dorrestein, Pieter CJournal of bacteriology2014 May1683-9324532776
Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection.Bassis, Christine M; Theriot, Casey M; Young, Vincent BAntimicrobial agents and chemotherapy2014 May2767-7424590475
Hepatic ATGL mediates PPAR-* signaling and fatty acid channeling through an L-FABP independent mechanism.Ong, Kuok Teong; Mashek, Mara T; Davidson, Nicholas O; Mashek, Douglas GJournal of lipid research2014 May808-1524610891
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.Guin, Sunny; Pollard, Courtney; Ru, Yuanbin; Ritterson Lew, Carolyn; Duex, Jason E; Dancik, Garrett; Owens, Charles; Spencer, Andrea; Knight, Scott; Holemon, Heather; Gupta, Sounak; Hansel, Donna; Hellerstein, Marc; Lorkiewicz, Pawel; Lane, Andrew N; Fan,Journal of the National Cancer Institute2014 MayNULL24700805
Quality control and conduct of genome-wide association meta-analyses.Winkler, Thomas W; Day, Felix R; Croteau-Chonka, Damien C; Wood, Andrew R; Locke, Adam E; Magi, Reedik; Ferreira, Teresa; Fall, Tove; Graff, Mariaelisa; Justice, Anne E; Luan, Jian'an; Gustafsson, Stefan; Randall, Joshua C; Vedantam, Sailaja; Workalemahu,Nature protocols2014 May1192-21224762786
Simulation of Finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland.Wang, Sophie R; Agarwala, Vineeta; Flannick, Jason; Chiang, Charleston W K; Altshuler, David; GoT2D Consortium; Hirschhorn, Joel NAmerican journal of human genetics2014 May 1710-2024768551
Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal.Sun, Deqiang; Luo, Min; Jeong, Mira; Rodriguez, Benjamin; Xia, Zheng; Hannah, Rebecca; Wang, Hui; Le, Thuc; Faull, Kym F; Chen, Rui; Gu, Hongcang; Bock, Christoph; Meissner, Alexander; Gottgens, Berthold; Darlington, Gretchen J; Li, Wei; Goodell, MargaretCell stem cell2014 May 1673-8824792119
Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma.Pferschy-Wenzig, Eva-Maria; Atanasov, Atanas G; Malainer, Clemens; Noha, Stefan M; Kunert, Olaf; Schuster, Daniela; Heiss, Elke H; Oberlies, Nicholas H; Wagner, Hildebert; Bauer, Rudolf; Dirsch, Verena MJournal of natural products2014 Apr 25842-724597776
Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.Nishizawa, Tomohiro; Kanter, Jenny E; Kramer, Farah; Barnhart, Shelley; Shen, Xia; Vivekanandan-Giri, Anuradha; Wall, Valerie Z; Kowitz, Jason; Devaraj, Sridevi; O'Brien, Kevin D; Pennathur, Subramaniam; Tang, Jingjing; Miyaoka, Robert S; Raines, Elaine WCell reports2014 Apr 24356-6524726364
MetDisease--connecting metabolites to diseases via literature.Duren, William; Weymouth, Terry; Hull, Tim; Omenn, Gilbert S; Athey, Brian; Burant, Charles; Karnovsky, AllaBioinformatics (Oxford, England)2014 Apr 23NULL24713438
Estimated GFR and Circulating 24,25-Dihydroxyvitamin D3ýýConcentration: A Participant-Level Analysis of 5 Cohort Studies and Clinical Trials.de Boer, Ian H; Sachs, Michael C; Chonchol, Michel; Himmelfarb, Jonathan; Hoofnagle, Andrew N; Ix, Joachim H; Kremsdorf, Robin A; Lin, Yvonne S; Mehrotra, Rajnish; Robinson-Cohen, Cassianne; Siscovick, David S; Steffes, Michael W; Thummel, Kenneth E; TracAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2014 Apr 3NULL24703961
Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives.Garay, Luis A; Boundy-Mills, Kyria L; German, J BruceJournal of agricultural and food chemistry2014 Apr 22709-2724628496
Longitudinal changes in estimated and measured GFR in type 1 diabetes.de Boer, Ian H; Sun, Wanjie; Cleary, Patricia A; Lachin, John M; Molitch, Mark E; Zinman, Bernard; Steffes, Michael W; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research GroupJournal of the American Society of Nephrology : JASN2014 Apr810-824309189
Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry.Baker, Erin Shammel; Burnum-Johnson, Kristin E; Jacobs, Jon M; Diamond, Deborah L; Brown, Roslyn N; Ibrahim, Yehia M; Orton, Daniel J; Piehowski, Paul D; Purdy, David E; Moore, Ronald J; Danielson 3rd, William F; Monroe, Matthew E; Crowell, Kevin L; SlyszMolecular & cellular proteomics : MCP2014 Apr1119-2724403597
Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females.Parlee, Sebastian D; Simon, Becky R; Scheller, Erica L; Alejandro, Emilyn U; Learman, Brian S; Krishnan, Venkatesh; Bernal-Mizrachi, Ernesto; MacDougald, Ormond AEndocrinology2014 Apr1313-2624456165
An Omega-3 Epoxide of Docosahexaenoic Acid Lowers Blood Pressure in Angiotensin-II Dependent Hypertension.Ulu, Arzu; Stephen Lee, Kin Sing; Miyabe, Christina; Yang, Jun; Hammock, Bruce G; Dong, Hua; Hammock, Bruce DJournal of cardiovascular pharmacology2014 Mar 31NULL24691274
Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets.O'Donnell, Valerie B; Murphy, Robert C; Watson, Steve PCirculation research2014 Mar 281185-20324677238
Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.Guzun, R; Kaambre, T; Bagur, R; Grichine, A; Usson, Y; Varikmaa, M; Anmann, T; Tepp, K; Timohhina, N; Shevchuk, I; Chekulayev, V; Boucher, F; Dos Santos, P; Schlattner, U; Wallimann, T; Kuznetsov, A V; Dzeja, P; Aliev, M; Saks, VActa physiologica (Oxford, England)2014 Mar 26NULL24666671
Continuous 24-Hour Leptin, Proopiomelanocortin and Amino Acid Measurements in Human Cerebrospinal Fluid: Correlations with Plasma Leptin, Soluble Leptin Receptor and Amino Acid Levels.Wardlaw, Sharon L; Burant, Charles F; Klein, Samuel; Meece, Kana; White, Anne; Kasten, Tom; Lucey, Brendan P; Bateman, Randall JThe Journal of clinical endocrinology and metabolism2014 Mar 26jc2013408724670082
Tracing phenolic metabolism in Vitis vinifera berries with 13C6-phenylalanine: implication of an unidentified intermediate reservoir.Chassy, Alexander W; Adams, Douglas O; Waterhouse, Andrew LJournal of agricultural and food chemistry2014 Mar 192321-624611798
An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases.Chan, Yingleong; Lim, Elaine T; Sandholm, Niina; Wang, Sophie R; McKnight, Amy Jayne; Ripke, Stephan; DIAGRAM Consortium; GENIE Consortium; GIANT Consortium; IIBDGC Consortium; PGC Consortium; Daly, Mark J; Neale, Benjamin M; Salem, Rany M; Hirschhorn, JoAmerican journal of human genetics2014 Mar 6437-5224607388
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice.Schuster, Gertrud U; Bratt, Jennifer M; Jiang, Xiaowen; Pedersen, Theresa L; Grapov, Dmitry; Adkins, Yuriko; Kelley, Darshan S; Newman, John W; Kenyon, Nicholas J; Stephensen, Charles BAmerican journal of respiratory cell and molecular biology2014 Mar626-3624134486
Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice.Zabielski, Piotr; Blachnio-Zabielska, Agnieszka; Lanza, Ian R; Gopala, Srinivas; Manjunatha, S; Jakaitis, Daniel R; Persson, Xuan-Mai; Gransee, Jaime; Klaus, Katherine A; Schimke, Jill M; Jensen, Michael D; Nair, K SreekumaranAmerican journal of physiology. Endocrinology and metabolism2014 Mar 1E529-4224368672
MOABS: model based analysis of bisulfite sequencing data.Sun, Deqiang; Xi, Yuanxin; Rodriguez, Benjamin; Park, Hyun Jung; Tong, Pan; Meong, Mira; Goodell, Margaret A; Li, WeiGenome biology2014 Feb 24R3824565500
Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.the KORA study groupEuropean journal of human genetics : EJHG2014 Feb 12NULL24518831
Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.Evans, Charles R; Karnovsky, Alla; Kovach, Melissa A; Standiford, Theodore J; Burant, Charles F; Stringer, Kathleen AJournal of proteome research2014 Feb 7640-924289193
X13CMS: global tracking of isotopic labels in untargeted metabolomics.Huang, Xiaojing; Chen, Ying-Jr; Cho, Kevin; Nikolskiy, Igor; Crawford, Peter A; Patti, Gary JAnalytical chemistry2014 Feb 41632-924397582
Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men.Schuchardt, Jan Philipp; Schmidt, Simone; Kressel, Gaby; Willenberg, Ina; Hammock, Bruce D; Hahn, Andreas; Schebb, Nils HelgeProstaglandins, leukotrienes, and essential fatty acids2014 Feb-Mar27-3724411718
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.Niewczas, Monika A; Sirich, Tammy L; Mathew, Anna V; Skupien, Jan; Mohney, Robert P; Warram, James H; Smiles, Adam; Huang, Xiaoping; Walker, Walker; Byun, Jaeman; Karoly, Edward D; Kensicki, Elizabeth M; Berry, Gerard T; Bonventre, Joseph V; Pennathur, SuKidney international2014 Jan 15NULL24429397
Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation.Whiteson, Katrine L; Meinardi, Simone; Lim, Yan Wei; Schmieder, Robert; Maughan, Heather; Quinn, Robert; Blake, Donald R; Conrad, Douglas; Rohwer, ForestThe ISME journal2014 Jan 9NULL24401860
Large conserved domains of low DNA methylation maintained by Dnmt3a.Jeong, Mira; Sun, Deqiang; Luo, Min; Huang, Yun; Challen, Grant A; Rodriguez, Benjamin; Zhang, Xiaotian; Chavez, Lukas; Wang, Hui; Hannah, Rebecca; Kim, Sang-Bae; Yang, Liubin; Ko, Myunggon; Chen, Rui; Gottgens, Berthold; Lee, Ju-Seog; Gunaratne, Preethi;Nature genetics2014 Jan17-2324270360
Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study.de Boer, Ian H; DCCT/EDIC Research GroupDiabetes care2014 Jan24-3024356594
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.Campbell, Caitlin; Grapov, Dmitry; Fiehn, Oliver; Chandler, Carol J; Burnett, Dustin J; Souza, Elaine C; Casazza, Gretchen A; Gustafson, Mary B; Keim, Nancy L; Newman, John W; Hunter, Gary R; Fernandez, Jose R; Garvey, W Timothy; Harper, Mary-Ellen; HoppePloS one2014e8426024416208
Hematopoietic stem cell development: an epigenetic journey.Cullen, Sean M; Mayle, Allison; Rossi, Lara; Goodell, Margaret ACurrent topics in developmental biology201439-7524439802
Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.Theriot, Casey M; Koenigsknecht, Mark J; Carlson Jr, Paul E; Hatton, Gabrielle E; Nelson, Adam M; Li, Bo; Huffnagle, Gary B; Z Li, Jun; Young, Vincent BNature communications2014311424445449
A genomic perspective on a new bacterial genus and species from the Alcaligenaceae family, Basilea psittacipulmonis.Whiteson, Katrine L; Hernandez, David; Lazarevic, Vladimir; Gaia, Nadia; Farinelli, Laurent; Francois, Patrice; Pilo, Paola; Frey, Joachim; Schrenzel, JacquesBMC genomics201416924581117
Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome.Roberts, Lee D; Koulman, Albert; Griffin, Julian LThe lancet. Diabetes & endocrinology2014 Jan65-7524622670
Biogeochemical forces shape the composition and physiology of polymicrobial communities in the cystic fibrosis lung.Quinn, Robert A; Lim, Yan Wei; Maughan, Heather; Conrad, Douglas; Rohwer, Forest; Whiteson, Katrine LmBio2014e00956-1324643867
Isotopic Ratio Outlier Analysis Global Metabolomics of Caenorhabditis elegans.Stupp, Gregory S; Clendinen, Chaevien S; Ajredini, Ramadan; Szewc, Mark A; Garrett, Timothy; Menger, Robert F; Yost, Richard A; Beecher, Chris; Edison, Arthur SAnalytical chemistry2013 Dec 1711858-6524274725
Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis.Gardell, Alison M; Yang, Jun; Sacchi, Romina; Fangue, Nann A; Hammock, Bruce D; Kultz, DietmarThe Journal of experimental biology2013 Dec 154615-2524072790
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.Kim, Soo Jin; Zhao, Hongbo; Hardikar, Swanand; Singh, Anup Kumar; Goodell, Margaret A; Chen, TaipingBlood2013 Dec 124086-924167195
A Metabolomics Investigation of Non-genotoxic Carcinogenicity in the Rat.Ament, Zsuzsanna; Waterman, Claire L; West, James A; Waterfield, Catherine; Currie, Richard A; Wright, Jayne; Griffin, Julian LJournal of proteome research2013 Dec 65775-9024161236
Constipation and a low-fiber diet are not associated with diverticulosis.Peery, Anne F; Sandler, Robert S; Ahnen, Dennis J; Galanko, Joseph A; Holm, Adrian N; Shaukat, Aasma; Mott, Leila A; Barry, Elizabeth L; Fried, David A; Baron, John AClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013 Dec1622-723891924
Division of mitochondria in cultured human fibroblasts.Fujioka, Hisashi; Tandler, Bernard; Consolo, Mary C; Karnik, PratimaMicroscopy research and technique2013 Dec1213-624009193
Human milk secretory immunoglobulin a and lactoferrin N-glycans are altered in women with gestational diabetes mellitus.Smilowitz, Jennifer T; Totten, Sarah M; Huang, Jincui; Grapov, Dmitry; Durham, Holiday A; Lammi-Keefe, Carol J; Lebrilla, Carlito; German, J BruceThe Journal of nutrition2013 Dec1906-1224047700
Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice.Zhang, Wanying; Li, Haonan; Dong, Hua; Liao, Jie; Hammock, Bruce D; Yang, Guang-YuAnticancer research2013 Dec5261-7124324059
Silibinin inhibits hepatitis C virus entry into hepatocytes by hindering clathrin-dependent trafficking.Blaising, Julie; Levy, Pierre L; Gondeau, Claire; Phelip, Capucine; Varbanov, Mihayl; Teissier, Elodie; Ruggiero, Florence; Polyak, Stephen J; Oberlies, Nicholas H; Ivanovic, Tijana; Boulant, Steeve; Pecheur, Eve-IsabelleCellular microbiology2013 Nov1866-8223701235
Microarray analysis of androgenetic and senescent alopecia: comparison of gene expression shows two distinct profiles.Karnik, Pratima; Shah, Selam; Dvorkin-Wininger, Yevgeniya; Oshtory, Shaheen; Mirmirani, ParadiJournal of dermatological science2013 Nov183-623886704
Preparation of 20-HETE using multifunctional enzyme type 2-negative Starmerella bombicola.Van Bogaert, Inge; Zhang, Guodong; Yang, Jun; Liu, Jun-Yan; Ye, Yonghao; Soetaert, Wim; Hammock, Bruce DJournal of lipid research2013 Nov3215-923966667
LC-IMS-MS Feature Finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets.Crowell, Kevin L; Slysz, Gordon W; Baker, Erin S; LaMarche, Brian L; Monroe, Matthew E; Ibrahim, Yehia M; Payne, Samuel H; Anderson, Gordon A; Smith, Richard DBioinformatics (Oxford, England)2013 Nov 12804-524008421
Vitamin D3 supplementation and upper respiratory tract infections in a randomized, controlled trial.Rees, Judy R; Hendricks, Kristy; Barry, Elizabeth L; Peacock, Janet L; Mott, Leila A; Sandler, Robert S; Bresalier, Robert S; Goodman, Michael; Bostick, Roberd M; Baron, John AClinical infectious diseases : an official publication of the Infectious Diseases Society of America2013 Nov1384-9224014734
Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications.Ghanta, Sirisha; Grossmann, Ruth E; Brenner, CharlesCritical reviews in biochemistry and molecular biology2013 Nov-Dec561-7424050258
Vitamin D deficiency: consequence or cause of CKD?de Boer, Ian H; Thadhani, RaviClinical journal of the American Society of Nephrology : CJASN2013 Nov1844-624135217
Hepatic fatty acid trafficking: multiple forks in the road.Mashek, Douglas GAdvances in nutrition (Bethesda, Md.)2013 Nov697-71024228201
Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction.Hinder, Lucy M; Figueroa-Romero, Claudia; Pacut, Crystal; Hong, Yu; Vivekanandan-Giri, Anuradha; Pennathur, Subramaniam; Feldman, Eva LAntioxidants & redox signaling2013 Oct 5NULL23991914
Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer.Wooding, Kerry M; Barkley, Robert M; Hankin, Joseph A; Johnson, Christopher A; Bradford, Andrew P; Santoro, Nanette; Murphy, Robert CJournal of the American Society for Mass Spectrometry2013 Oct1451-523955001
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.Frolov, Andrey; Yang, Lihua; Dong, Hua; Hammock, Bruce D; Crofford, Leslie JProstaglandins, leukotrienes, and essential fatty acids2013 Oct351-824055573
A Computational Framework for High-Throughput Isotopic Natural Abundance Correction of Omics-Level Ultra-High Resolution FT-MS Datasets.Carreer, William J; Flight, Robert M; Moseley, Hunter N BMetabolites2013 Sep 25NULL24404440
Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate.Davda, Dahvid; El Azzouny, Mahmoud A; Tom, Christopher T M B; Hernandez, Jeannie L; Majmudar, Jaimeen D; Kennedy, Robert T; Martin, Brent RACS chemical biology2013 Sep 201912-723844586
Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third national health and nutrition examination survey.Hernaez, Ruben; McLean, Jody; Lazo, Mariana; Brancati, Frederick L; Hirschhorn, Joel N; Borecki, Ingrid B; Harris, Tamara B; Genetics of Obesity-Related Liver Disease (GOLD) Consortium; Nguyen, Thutrang; Kamel, Ihab R; Bonekamp, Susanne; Eberhardt, Mark SClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013 Sep1183-1190.e223416328
Cortisol response to operative stress with anesthesia in healthy children.Taylor, Lisa K; Auchus, Richard J; Baskin, Laurence S; Miller, Walter LThe Journal of clinical endocrinology and metabolism2013 Sep3687-9323861461
An untargeted metabolomic workflow to improve structural characterization of metabolites.Nikolskiy, Igor; Mahieu, Nathaniel G; Chen, Ying-Jr; Tautenhahn, Ralf; Patti, Gary JAnalytical chemistry2013 Aug 207713-923829391
Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.Frolov, Andrey; Dong, Hua; Jiang, Min; Yang, Lihua; Cook, Erik C; Matnani, Rahul; Hammock, Bruce D; Crofford, Leslie JThe Journal of biological chemistry2013 Aug 1623696-70323814065
Mechanistic study of the biomimetic synthesis of flavonolignan diastereoisomers in milk thistle.Althagafy, Hanan S; Meza-Avina, Maria Elena; Oberlies, Nicholas H; Croatt, Mitchell PThe Journal of organic chemistry2013 Aug 27594-60023876147
Circulating vitamin D metabolites and subclinical atherosclerosis in type 1 diabetes.Sachs, Michael C; Brunzell, John D; Cleary, Patricia A; Hoofnagle, Andrew N; Lachin, John M; Molitch, Mark E; Steffes, Michael W; Zinman, Bernard; de Boer, Ian H; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and ComplicaDiabetes care2013 Aug2423-923530012
LipidBlast in silico tandem mass spectrometry database for lipid identification.Kind, Tobias; Liu, Kwang-Hyeon; Lee, Do Yup; Defelice, Brian; Meissen, John K; Fiehn, OliverNature methods2013 Aug755-823817071
Nutritional lipidomics: molecular metabolism, analytics, and diagnostics.Smilowitz, Jennifer T; Zivkovic, Angela M; Wan, Yu-Jui Yvonne; Watkins, Steve M; Nording, Malin L; Hammock, Bruce D; German, J BruceMolecular nutrition & food research2013 Aug1319-3523818328
Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass.Saeidi, Nima; Meoli, Luca; Nestoridi, Eirini; Gupta, Nitin K; Kvas, Stephanie; Kucharczyk, John; Bonab, Ali A; Fischman, Alan J; Yarmush, Martin L; Stylopoulos, NicholasScience (New York, N.Y.)2013 Jul 26406-1023888041
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.Asai, Masato; Ramachandrappa, Shwetha; Joachim, Maria; Shen, Yuan; Zhang, Rong; Nuthalapati, Nikhil; Ramanathan, Visali; Strochlic, David E; Ferket, Peter; Linhart, Kirsten; Ho, Caroline; Novoselova, Tatiana V; Garg, Sumedha; Ridderstrale, Martin; Marcus,Science (New York, N.Y.)2013 Jul 19275-823869016
Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism.Ivanisevic, Julijana; Zhu, Zheng-Jiang; Plate, Lars; Tautenhahn, Ralf; Chen, Stephen; O'Brien, Peter J; Johnson, Caroline H; Marletta, Michael A; Patti, Gary J; Siuzdak, GaryAnalytical chemistry2013 Jul 166876-8423781873
MS/MS networking guided analysis of molecule and gene cluster families.Nguyen, Don Duy; Wu, Cheng-Hsuan; Moree, Wilna J; Lamsa, Anne; Medema, Marnix H; Zhao, Xiling; Gavilan, Ronnie G; Aparicio, Marystella; Atencio, Librada; Jackson, Chanaye; Ballesteros, Javier; Sanchez, Joel; Watrous, Jeramie D; Phelan, Vanessa V; van de WProceedings of the National Academy of Sciences of the United States of America2013 Jul 9E2611-2023798442
HR-MAS NMR Tissue Metabolomic Signatures Cross-validated by Mass Spectrometry Distinguish Bladder Cancer from Benign Disease.Tripathi, Pratima; Somashekar, Bagganahalli S; Ponnusamy, M; Gursky, Amy; Dailey, Stephen; Kunju, Priya; Lee, Cheryl T; Chinnaiyan, Arul M; Rajendiran, Thekkelnaycke M; Ramamoorthy, AyyalusamyJournal of proteome research2013 Jul 53519-2823731241
X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic ýý-Cell Function.Akiyama, Masaru; Liew, Chong Wee; Lu, Shusheng; Hu, Jiang; Martinez, Rachael; Hambro, Ben; Kennedy, Robert T; Kulkarni, Rohit NDiabetes2013 Jul2439-4923493568
Obesity-induced diabetes and lower urinary tract fibrosis promote urinary voiding dysfunction in a mouse model.Gharaee-Kermani, Mehrnaz; Rodriguez-Nieves, Jose A; Mehra, Rohit; Vezina, Chad A; Sarma, Aruna V; Macoska, Jill AThe Prostate2013 Jul1123-3323532836
Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle.Althagafy, Hanan S; Graf, Tyler N; Sy-Cordero, Arlene A; Gufford, Brandon T; Paine, Mary F; Wagoner, Jessica; Polyak, Stephen J; Croatt, Mitchell P; Oberlies, Nicholas HBioorganic & medicinal chemistry2013 Jul 13919-2623673225
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Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.McDonnell, Scott R P; Hwang, Steven R; Rolland, Delphine; Murga-Zamalloa, Carlos; Basrur, Venkatesha; Conlon, Kevin P; Fermin, Damian; Wolfe, Thomas; Raskind, Alexander; Ruan, Chunhai; Jiang, Jian-Kang; Thomas, Craig J; Hogaboam, Cory M; Burant, Charles FBlood2013 Jun 27NULL23814019
Bacteriophage adhering to mucus provide a non-host-derived immunity.Barr, Jeremy J; Auro, Rita; Furlan, Mike; Whiteson, Katrine L; Erb, Marcella L; Pogliano, Joe; Stotland, Aleksandr; Wolkowicz, Roland; Cutting, Andrew S; Doran, Kelly S; Salamon, Peter; Youle, Merry; Rohwer, ForestProceedings of the National Academy of Sciences of the United States of America2013 Jun 2510771-623690590
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.Monda, Keri L; Chen, Gary K; Taylor, Kira C; Palmer, Cameron; Edwards, Todd L; Lange, Leslie A; Ng, Maggie C Y; Adeyemo, Adebowale A; Allison, Matthew A; Bielak, Lawrence F; Chen, Guanjie; Graff, Mariaelisa; Irvin, Marguerite R; Rhie, Suhn K; Li, Guo; LiuNature genetics2013 Jun690-623583978
Optimization of harvesting, extraction, and analytical protocols for UPLC-ESI-MS-based metabolomic analysis of adherent mammalian cancer cells.Bi, Huichang; Krausz, Kristopher W; Manna, Soumen K; Li, Fei; Johnson, Caroline H; Gonzalez, Frank JAnalytical and bioanalytical chemistry2013 Jun5279-8923604415
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Developmental programming: impact of prenatal testosterone excess on insulin sensitivity, adiposity, and free fatty acid profile in postpubertal female sheep.Veiga-Lopez, A; Moeller, J; Patel, D; Ye, W; Pease, A; Kinns, J; Padmanabhan, VEndocrinology2013 May1731-4223525243
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High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.Vivekanandan-Giri, Anuradha; Slocum, Jessica L; Byun, Jaeman; Tang, Chongren; Sands, Robin L; Gillespie, Brenda W; Heinecke, Jay W; Saran, Rajiv; Kaplan, Mariana J; Pennathur, SubramaniamAnnals of the rheumatic diseases2013 Jan 12NULL23313808
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New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.Horikoshi, Momoko; Yaghootkar, Hanieh; Mook-Kanamori, Dennis O; Sovio, Ulla; Taal, H Rob; Hennig, Branwen J; Bradfield, Jonathan P; St Pourcain, Beate; Evans, David M; Charoen, Pimphen; Kaakinen, Marika; Cousminer, Diana L; Lehtimaki, Terho; Kreiner-MolleNature genetics2013 Jan76-8223202124
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Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung, based on a genome reconstructed from metagenomic data.Lim, Yan Wei; Schmieder, Robert; Haynes, Matthew; Furlan, Mike; Matthews, T David; Whiteson, Katrine; Poole, Stephen J; Hayes, Christopher S; Low, David A; Maughan, Heather; Edwards, Robert; Conrad, Douglas; Rohwer, ForestPloS one2013e6428523737977
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Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung.Yang, Jun; Solaimani, Parrisa; Dong, Hua; Hammock, Bruce; Hankinson, OliverThe Journal of toxicological sciences2013833-624213002
Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging.O'Brien, Peter J; Lee, Michelle; Spilker, Mary E; Zhang, Cathy C; Yan, Zhengming; Nichols, Timothy C; Li, Wenlin; Johnson, Caroline H; Patti, Gary J; Siuzdak, GaryCancer & metabolism2013424280026
A prospective study of frailty in nephrology-referred patients with CKD.Roshanravan, Baback; Khatri, Minesh; Robinson-Cohen, Cassianne; Levin, Greg; Patel, Kushang V; de Boer, Ian H; Seliger, Stephen; Ruzinski, John; Himmelfarb, Jonathan; Kestenbaum, BryanAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2012 Dec912-2122770927
Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height.Lui, Julian C; Nilsson, Ola; Chan, Yingleong; Palmer, Cameron D; Andrade, Anenisia C; Hirschhorn, Joel N; Baron, JeffreyHuman molecular genetics2012 Dec 15193-20122914739
Absolute Configuration of Isosilybin A by X-ray Crystallography of the Heavy Atom Analogue 7-(4-Bromobenzoyl)isosilybin A.Sy-Cordero, Arlene A; Day, Cynthia S; Oberlies, Nicholas HJournal of natural products2012 Nov 1NULL23116206
Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 ýý.McInturff, Alison M; Cody, Mark J; Elliott, Elizabeth A; Glenn, Jared W; Rowley, Jesse W; Rondina, Matthew T; Yost, Christian CBlood2012 Oct 113118-2522919032
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Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.Rossi, Lara; Lin, Kuanyin K; Boles, Nathan C; Yang, Liubin; King, Katherine Y; Jeong, Mira; Mayle, Allison; Goodell, Margaret ACell stem cell2012 Sep 7302-1722958929
The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease.Bosworth, Cortney R; Levin, Gregory; Robinson-Cohen, Cassianne; Hoofnagle, Andrew N; Ruzinski, John; Young, Bessie; Schwartz, Stephen M; Himmelfarb, Jonathan; Kestenbaum, Bryan; de Boer, Ian HKidney international2012 Sep693-70022648296
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Evidence of widespread selection on standing variation in Europe at height-associated SNPs.Turchin, Michael C; Chiang, Charleston W K; Palmer, Cameron D; Sankararaman, Sriram; Reich, David; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Hirschhorn, Joel NNature genetics2012 Sep1015-922902787
Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities.Lim, Yan Wei; Schmieder, Robert; Haynes, Matthew; Willner, Dana; Furlan, Mike; Youle, Merry; Abbott, Katelynn; Edwards, Robert; Evangelista, Jose; Conrad, Douglas; Rohwer, ForestJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2012 Aug 28NULL22951208
Multicellularity and antibiotic resistance in Klebsiella pneumoniae grown under bloodstream-mimicking fluid dynamic conditions.Thornton, Margaret M; Chung-Esaki, Hangyul M; Irvin, Charlene B; Bortz, David M; Solomon, Michael J; Younger, John GThe Journal of infectious diseases2012 Aug 15588-9522711903
The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.Zohren, Fabian; Souroullas, George P; Luo, Min; Gerdemann, Ulrike; Imperato, Maria R; Wilson, Nicola K; Gottgens, Berthold; Lukov, Georgi L; Goodell, Margaret ANature immunology2012 Aug761-922772404
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Insulin resistance, cystatin C, and mortality among older adults.de Boer, Ian H; Katz, Ronit; Chonchol, Michel B; Fried, Linda F; Ix, Joachim H; Kestenbaum, Bryan; Mukamal, Kenneth J; Peralta, Carmen A; Siscovick, David SDiabetes care2012 Jun1355-6022432118
Cicatricial Alopecia Symposium 2011: Lipids, inflammation and stem cells.Karnik, Pratima; Stenn, KurtThe Journal of investigative dermatology2012 Jun1529-3122584498
Calcium, magnesium, and colorectal cancer.Dai, Qi; Sandler, Robert; Barry, Elizabeth; Summers, Robert; Grau, Maria; Baron, JohnEpidemiology (Cambridge, Mass.)2012 May504-522475836
A genome-wide association meta-analysis identifies new childhood obesity loci.Bradfield, Jonathan P; Taal, H Rob; Timpson, Nicholas J; Scherag, Andre; Lecoeur, Cecile; Warrington, Nicole M; Hypponen, Elina; Holst, Claus; Valcarcel, Beatriz; Thiering, Elisabeth; Salem, Rany M; Schumacher, Fredrick R; Cousminer, Diana L; Sleiman, PatNature genetics2012 May526-3122484627
Chronic kidney disease, insulin resistance, and incident diabetes in older adults.Pham, Hien; Robinson-Cohen, Cassianne; Biggs, Mary L; Ix, Joachim H; Mukamal, Kenneth J; Fried, Linda F; Kestenbaum, Bryan; Siscovick, David S; de Boer, Ian HClinical journal of the American Society of Nephrology : CJASN2012 Apr588-9422383749
Gencrypt: one-way cryptographic hashes to detect overlapping individuals across samples.Turchin, Michael C; Hirschhorn, Joel NBioinformatics (Oxford, England)2012 Mar 15886-822302573
Spatial distribution of microbial communities in the cystic fibrosis lung.Willner, Dana; Haynes, Matthew R; Furlan, Mike; Schmieder, Robert; Lim, Yan Wei; Rainey, Paul B; Rohwer, Forest; Conrad, DouglasThe ISME journal2012 Feb471-421796216
Case studies of the spatial heterogeneity of DNA viruses in the cystic fibrosis lung.Willner, Dana; Haynes, Matthew R; Furlan, Mike; Hanson, Nicole; Kirby, Breeann; Lim, Yan Wei; Rainey, Paul B; Schmieder, Robert; Youle, Merry; Conrad, Douglas; Rohwer, ForestAmerican journal of respiratory cell and molecular biology2012 Feb127-3121980056
A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses.Polyak, Stephen J; Morishima, Chihiro; Scott, John D; Gastaminza, Pablo; Cox, Andrea; de Araujo, Evaldo Stanislau Affonso; Higgs, Martin R; Loo, Yueh-Ming; Golden-Mason, Lucy; Lindenbach, Brett D; Baumert, Thomas F; Randall, Glenn; Gale Jr, MichaelGastroenterology2012 Jane1-522185796
Genome-wide association and functional follow-up reveals new loci for kidney function.Pattaro, Cristian; Kottgen, Anna; Teumer, Alexander; Garnaas, Maija; Boger, Carsten A; Fuchsberger, Christian; Olden, Matthias; Chen, Ming-Huei; Tin, Adrienne; Taliun, Daniel; Li, Man; Gao, Xiaoyi; Gorski, Mathias; Yang, Qiong; Hundertmark, Claudia; FostePLoS genetics2012e100258422479191
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS genetics2012e100260722479202
Sterol intermediates of cholesterol biosynthesis inhibit hair growth and trigger an innate immune response in cicatricial alopecia.Panicker, Sreejith P; Ganguly, Taneeta; Consolo, Mary; Price, Vera; Mirmirani, Paradi; Honda, Kord; Karnik, PratimaPloS one2012e3844922685570
Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation.McClure, Janela; Lovelace, Erica S; Elahi, Shokrollah; Maurice, Nicholas J; Wagoner, Jessica; Dragavon, Joan; Mittler, John E; Kraft, Zane; Stamatatos, Leonidis; Horton, Helen; De Rosa, Stephen C; Coombs, Robert W; Polyak, Stephen JPloS one2012e4183222848626
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The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA.Chiang, Charleston W K; Gajdos, Zofia K Z; Korn, Joshua M; Butler, Johannah L; Hackett, Rachel; Guiducci, Candace; Nguyen, Thutrang T; Wilks, Rainford; Forrester, Terrence; Henderson, Katherine D; Le Marchand, Loic; Henderson, Brian E; Haiman, ChristopherHuman genetics2011 Nov607-2121424828
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Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.N'Diaye, Amidou; Chen, Gary K; Palmer, Cameron D; Ge, Bing; Tayo, Bamidele; Mathias, Rasika A; Ding, Jingzhong; Nalls, Michael A; Adeyemo, Adebowale; Adoue, Veronique; Ambrosone, Christine B; Atwood, Larry; Bandera, Elisa V; Becker, Lewis C; Berndt, SonjaPLoS genetics2011 Octe100229821998595
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Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.Boger, Carsten A; Gorski, Mathias; Li, Man; Hoffmann, Michael M; Huang, Chunmei; Yang, Qiong; Teumer, Alexander; Krane, Vera; O'Seaghdha, Conall M; Kutalik, Zoltan; Wichmann, H-Erich; Haak, Thomas; Boes, Eva; Coassin, Stefan; Coresh, Josef; Kollerits, BarPLoS genetics2011 Sepe100229221980298
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.Kilpelainen, Tuomas O; Zillikens, M Carola; Stancakova, Alena; Finucane, Francis M; Ried, Janina S; Langenberg, Claudia; Zhang, Weihua; Beckmann, Jacques S; Luan, Jian'an; Vandenput, Liesbeth; Styrkarsdottir, Unnur; Zhou, Yanhua; Smith, Albert Vernon; ZhaNature genetics2011 Aug753-6021706003
Temporal trends in the prevalence of diabetic kidney disease in the United States.de Boer, Ian H; Rue, Tessa C; Hall, Yoshio N; Heagerty, Patrick J; Weiss, Noel S; Himmelfarb, JonathanJAMA : the journal of the American Medical Association2011 Jun 222532-921693741
Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.Del Greco M, Fabiola; Pattaro, Cristian; Luchner, Andreas; Pichler, Irene; Winkler, Thomas; Hicks, Andrew A; Fuchsberger, Christian; Franke, Andre; Melville, Scott A; Peters, Annette; Wichmann, H Erich; Schreiber, Stefan; Heid, Iris M; Krawczak, Michael; Human molecular genetics2011 Apr 151660-7121273288
Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria: an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort.de Boer, Ian H; Rue, Tessa C; Cleary, Patricia A; Lachin, John M; Molitch, Mark E; Steffes, Michael W; Sun, Wanjie; Zinman, Bernard; Brunzell, John D; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Archives of internal medicine2011 Mar 14412-2021403038
CUBN is a gene locus for albuminuria.Boger, Carsten A; Chen, Ming-Huei; Tin, Adrienne; Olden, Matthias; Kottgen, Anna; de Boer, Ian H; Fuchsberger, Christian; O'Seaghdha, Conall M; Pattaro, Cristian; Teumer, Alexander; Liu, Ching-Ti; Glazer, Nicole L; Li, Man; O'Connell, Jeffrey R; Tanaka, TJournal of the American Society of Nephrology : JASN2011 Mar555-7021355061
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.Speliotes, Elizabeth K; Yerges-Armstrong, Laura M; Wu, Jun; Hernaez, Ruben; Kim, Lauren J; Palmer, Cameron D; Gudnason, Vilmundur; Eiriksdottir, Gudny; Garcia, Melissa E; Launer, Lenore J; Nalls, Michael A; Clark, Jeanne M; Mitchell, Braxton D; Shuldiner,PLoS genetics2011 Mare100132421423719
First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.Holzapfel, Christina; Grallert, Harald; Baumert, Jens; Thorand, Barbara; Doring, Angela; Wichmann, H Erich; Hauner, Hans; Illig, Thomas; Mielck, AndreasJournal of epidemiology and community health2011 Feb174-620628085
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning.Ong, Kuok Teong; Mashek, Mara T; Bu, So Young; Greenberg, Andrew S; Mashek, Douglas GHepatology (Baltimore, Md.)2011 Jan116-2620967758
Hematopoietic stem cell characterization and isolation.Rossi, Lara; Challen, Grant A; Sirin, Olga; Lin, Karen Kuan-Yin; Goodell, Margaret AMethods in molecular biology (Clifton, N.J.)201147-5921618082
Detection of hematopoietic stem cells by flow cytometry.Lin, Kuanyin K; Goodell, Magaret AMethods in cell biology201121-3021722798
Dynamics of human complement-mediated killing of Klebsiella pneumoniae.Nypaver, Christina M; Thornton, Margaret M; Yin, Suellen M; Bracho, David O; Nelson, Patrick W; Jones, Alan E; Bortz, David M; Younger, John GAmerican journal of respiratory cell and molecular biology2010 Nov585-9020008281
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature genetics2010 Nov949-6020935629
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature genetics2010 Nov937-4820935630
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature2010 Oct 14832-820881960
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome.Pan, Feng; Aldridge, Georgina M; Greenough, William T; Gan, Wen-BiaoProceedings of the National Academy of Sciences of the United States of America2010 Oct 1217768-7320861447
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.Holzapfel, C; Grallert, H; Huth, C; Wahl, S; Fischer, B; Doring, A; Ruckert, I M; Hinney, A; Hebebrand, J; Wichmann, H-E; Hauner, H; Illig, T; Heid, I MInternational journal of obesity (2005)2010 Oct1538-4520386550
PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.Speliotes, Elizabeth K; Butler, Johannah L; Palmer, Cameron D; Voight, Benjamin F; GIANT Consortium; MIGen Consortium; NASH CRN; Hirschhorn, Joel NHepatology (Baltimore, Md.)2010 Sep904-1220648472
Fine mapping of the association with obesity at the FTO locus in African-derived populations.Hassanein, Mohamed T; Lyon, Helen N; Nguyen, Thutrang T; Akylbekova, Ermeg L; Waters, Kevin; Lettre, Guillaume; Tayo, Bamidele; Forrester, Terrence; Sarpong, Daniel F; Stram, Dan O; Butler, Johannah L; Wilks, Rainford; Liu, Jiankang; Le Marchand, Loic; KoHuman molecular genetics2010 Jul 152907-1620430937
Genome-wide association of anthropometric traits in African- and African-derived populations.Kang, Sun J; Chiang, Charleston W K; Palmer, Cameron D; Tayo, Bamidele O; Lettre, Guillaume; Butler, Johannah L; Hackett, Rachel; Adeyemo, Adebowale A; Guiducci, Candace; Berzins, Ilze; Nguyen, Thutrang T; Feng, Tao; Luke, Amy; Shriner, Daniel; Ardlie, KrHuman molecular genetics2010 Jul 12725-3820400458
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.Freathy, Rachel M; Mook-Kanamori, Dennis O; Sovio, Ulla; Prokopenko, Inga; Timpson, Nicholas J; Berry, Diane J; Warrington, Nicole M; Widen, Elisabeth; Hottenga, Jouke Jan; Kaakinen, Marika; Lange, Leslie A; Bradfield, Jonathan P; Kerkhof, Marjan; Marsh, Nature genetics2010 May430-520372150
New loci associated with kidney function and chronic kidney disease.Kottgen, Anna; Pattaro, Cristian; Boger, Carsten A; Fuchsberger, Christian; Olden, Matthias; Glazer, Nicole L; Parsa, Afshin; Gao, Xiaoyi; Yang, Qiong; Smith, Albert V; O'Connell, Jeffrey R; Li, Man; Schmidt, Helena; Tanaka, Toshiko; Isaacs, Aaron; KetkarNature genetics2010 May376-8420383146
Lipids to the top of hair biology.Stenn, Kurt S; Karnik, PratimaThe Journal of investigative dermatology2010 May1205-720393475
Complement activation in emergency department patients with severe sepsis.Younger, John G; Bracho, David O; Chung-Esaki, Hangyul M; Lee, Moonseok; Rana, Gurpreet K; Sen, Ananda; Jones, Alan EAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2010 Apr353-920370773
Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples.Chiang, Charleston W K; Gajdos, Zofia K Z; Korn, Joshua M; Kuruvilla, Finny G; Butler, Johannah L; Hackett, Rachel; Guiducci, Candace; Nguyen, Thutrang T; Wilks, Rainford; Forrester, Terrence; Haiman, Christopher A; Henderson, Katherine D; Le Marchand, LoPLoS genetics2010 Mare100086620221249
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.Heid, Iris M; Henneman, Peter; Hicks, Andrew; Coassin, Stefan; Winkler, Thomas; Aulchenko, Yurii S; Fuchsberger, Christian; Song, Kijoung; Hivert, Marie-France; Waterworth, Dawn M; Timpson, Nicholas J; Richards, J Brent; Perry, John R B; Tanaka, Toshiko; Atherosclerosis2010 Feb412-2020018283
Lichen planopilaris treated with a peroxisome proliferator-activated receptor gamma agonist.Mirmirani, Paradi; Karnik, PratimaArchives of dermatology2009 Dec1363-620026843
Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?Heid, Iris M; Huth, Cornelia; Loos, Ruth J F; Kronenberg, Florian; Adamkova, Vera; Anand, Sonia S; Ardlie, Kristin; Biebermann, Heike; Bjerregaard, Peter; Boeing, Heiner; Bouchard, Claude; Ciullo, Marina; Cooper, Jackie A; Corella, Dolores; Dina, ChristiaPLoS genetics2009 Octe100069419851442
Flexible microfluidic device for mechanical property characterization of soft viscoelastic solids such as bacterial biofilms.Hohne, Danial N; Younger, John G; Solomon, Michael JLangmuir : the ACS journal of surfaces and colloids2009 Jul 77743-5119219968
No association of two functional polymorphisms in human ALOX15 with myocardial infarction.Hersberger, Martin; Muller, Martina; Marti-Jaun, Jacqueline; Heid, Iris M; Coassin, Stefan; Young, Thomas F; Waechter, Vanessa; Hengstenberg, Christian; Meisinger, Christine; Peters, Annette; Konig, Wolfgang; Holmer, Stephan; Schunkert, Heribert; Klopp, NAtherosclerosis2009 Jul192-619131063
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.Lindgren, Cecilia M; Heid, Iris M; Randall, Joshua C; Lamina, Claudia; Steinthorsdottir, Valgerdur; Qi, Lu; Speliotes, Elizabeth K; Thorleifsson, Gudmar; Willer, Cristen J; Herrera, Blanca M; Jackson, Anne U; Lim, Noha; Scheet, Paul; Soranzo, Nicole; AminPLoS genetics2009 June100050819557161
Hair follicle stem cell-specific PPARgamma deletion causes scarring alopecia.Karnik, Pratima; Tekeste, Zenar; McCormick, Thomas S; Gilliam, Anita C; Price, Vera H; Cooper, Kevin D; Mirmirani, ParadiThe Journal of investigative dermatology2009 May1243-5719052558
Use of weighted reference panels based on empirical estimates of ancestry for capturing untyped variation.Egyud, Matthew R L; Gajdos, Zofia K Z; Butler, Johannah L; Tischfield, Sam; Le Marchand, Loic; Kolonel, Laurence N; Haiman, Christopher A; Henderson, Brian E; Hirschhorn, Joel NHuman genetics2009 Apr295-30319184111
Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.Boes, Eva; Coassin, Stefan; Kollerits, Barbara; Heid, Iris M; Kronenberg, FlorianExperimental gerontology2009 Mar136-6019041386
Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: observational follow-up of a randomized study.Grau, Maria V; Sandler, Robert S; McKeown-Eyssen, Gail; Bresalier, Robert S; Haile, Robert W; Barry, Elizabeth L; Ahnen, Dennis J; Gui, Jiang; Summers, Robert W; Baron, John AJournal of the National Cancer Institute2009 Feb 18267-7619211442
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.Willer, Cristen J; Speliotes, Elizabeth K; Loos, Ruth J F; Li, Shengxu; Lindgren, Cecilia M; Heid, Iris M; Berndt, Sonja I; Elliott, Amanda L; Jackson, Anne U; Lamina, Claudia; Lettre, Guillaume; Lim, Noha; Lyon, Helen N; McCarroll, Steven A; Papadakis, KNature genetics2009 Jan25-3419079261
Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.Singmann, Paula; Baumert, Jens; Herder, Christian; Meisinger, Christa; Holzapfel, Christina; Klopp, Norman; Wichmann, H-Erich; Klingenspor, Martin; Rathmann, Wolfgang; Illig, Thomas; Grallert, HaraldObesity facts2009235-4220054229
Dynamical system analysis of Staphylococcus epidermidis bloodstream infection.Chung, Hangyul M; Cartwright, Megan M; Bortz, David M; Jackson, Trachette L; Younger, John GShock (Augusta, Ga.)2008 Nov518-2618317411
Genome-wide association studies: implications for multiethnic samples.Cooper, Richard S; Tayo, Bamidele; Zhu, XiaofengHuman molecular genetics2008 Oct 15R151-518852204
Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons.Pichler, Michaela; Kollerits, Barbara; Heid, Iris M; Hunt, Steven C; Adams, Ted D; Hopkins, Paul N; Kronenberg, FlorianThe American journal of clinical nutrition2008 Sep797-80018779298
Identification of ten loci associated with height highlights new biological pathways in human growth.Lettre, Guillaume; Jackson, Anne U; Gieger, Christian; Schumacher, Fredrick R; Berndt, Sonja I; Sanna, Serena; Eyheramendy, Susana; Voight, Benjamin F; Butler, Johannah L; Guiducci, Candace; Illig, Thomas; Hackett, Rachel; Heid, Iris M; Jacobs, Kevin B; LNature genetics2008 May584-9118391950
Klebsiella pneumoniae flocculation dynamics.Bortz, D M; Jackson, T L; Taylor, K A; Thompson, A P; Younger, J GBulletin of mathematical biology2008 Apr745-6818071828
On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test.Ionita-Laza, Iuliana; Perry, George H; Raby, Benjamin A; Klanderman, Barbara; Lee, Charles; Laird, Nan M; Weiss, Scott T; Lange, ChristophGenetic epidemiology2008 Apr273-8418228561
Leptin improves pulmonary bacterial clearance and survival in ob/ob mice during pneumococcal pneumonia.Hsu, A; Aronoff, D M; Phipps, J; Goel, D; Mancuso, PClinical and experimental immunology2007 Nov332-917822444
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial.Grau, Maria V; Baron, John A; Sandler, Robert S; Wallace, Kristin; Haile, Robert W; Church, Timothy R; Beck, Gerald J; Summers, Robert W; Barry, Elizabeth L; Cole, Bernard F; Snover, Dale C; Rothstein, Richard; Mandel, Jack SJournal of the National Cancer Institute2007 Jan 17129-3617227996
Generation of C5a in the absence of C3: a new complement activation pathway.Huber-Lang, Markus; Sarma, J Vidya; Zetoune, Firas S; Rittirsch, Daniel; Neff, Thomas A; McGuire, Stephanie R; Lambris, John D; Warner, Roscoe L; Flierl, Michael A; Hoesel, Laszlo M; Gebhard, Florian; Younger, John G; Drouin, Scott M; Wetsel, Rick A; WardNature medicine2006 Jun682-716715088
Dynamics of intrapulmonary bacterial growth in a murine model of repeated microaspiration.Ben-David, Itzhak; Price, Sarah E; Bortz, David M; Greineder, Colin F; Cohen, Samuel E; Bauer, Amy L; Jackson, Trachette L; Younger, John GAmerican journal of respiratory cell and molecular biology2005 Nov476-8216014897
Complement C5 and early oxygen kinetics during murine sepsis.Valencia, Gabriel; Sarma, J Vidya; Younger, John GAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2005 Apr275-8115805316

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