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Structural Biology (512)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.Weierstall, Uwe; James, Daniel; Wang, Chong; White, Thomas A; Wang, Dingjie; Liu, Wei; Spence, John C H; Bruce Doak, R; Nelson, Garrett; Fromme, Petra; Fromme, Raimund; Grotjohann, Ingo; Kupitz, Christopher; Zatsepin, Nadia A; Liu, Haiguang; Basu, Shibom;Nature communications2014 Feb 14330924525480
Structure of sugar-bound LacY.Kumar, Hemant; Kasho, Vladimir; Smirnova, Irina; Finer-Moore, Janet S; Kaback, H Ronald; Stroud, Robert MProceedings of the National Academy of Sciences of the United States of America2014 Feb 41784-824453216
Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels.Zhao, Jun; Hu, Rundong; Sciacca, Michele F M; Brender, Jeffrey R; Chen, Hong; Ramamoorthy, Ayyalusamy; Zheng, JiePhysical chemistry chemical physics : PCCP2014 Jan 152368-7724352606
Molecular control of ýý-opioid receptor signalling.Fenalti, Gustavo; Giguere, Patrick M; Katritch, Vsevolod; Huang, Xi-Ping; Thompson, Aaron A; Cherezov, Vadim; Roth, Bryan L; Stevens, Raymond CNature2014 Jan 12NULL24413399
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.Lee, Sanghyun; Zheng, Xueyun; Krishnamoorthy, Janarthanan; Savelieff, Masha G; Park, Hyun Min; Brender, Jeffrey R; Kim, Jin Hoon; Derrick, Jeffrey S; Kochi, Akiko; Lee, Hyuck Jin; Kim, Cheal; Ramamoorthy, Ayyalusamy; Bowers, Michael T; Lim, Mi HeeJournal of the American Chemical Society2014 Jan 8299-31024397771
Protein structural ensembles are revealed by redefining X-ray electron density noise.Lang, P Therese; Holton, James M; Fraser, James S; Alber, TomProceedings of the National Academy of Sciences of the United States of America2014 Jan 7237-4224363322
Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy.Higashi, Kenjirou; Yamamoto, Kazutoshi; Pandey, Manoj Kumar; Mroue, Kamal H; Moribe, Kunikazu; Yamamoto, Keiji; Ramamoorthy, AyyalusamyMolecular pharmaceutics2014 Jan 6351-724283196
Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation.Chae, Pil Seok; Cho, Kyung Ho; Wander, Marc J; Bae, Hyoung Eun; Gellman, Samuel H; Laible, Philip DBiochimica et biophysica acta2014 Jan278-8624064323
Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion.Chae, Pil Seok; Sadaf, Aiman; Gellman, Samuel HChemistry, an Asian journal2014 Jan110-624347070
Structure-based mechanism for Na(+)/melibiose symport by MelB.Ethayathulla, Abdul S; Yousef, Mohammad S; Amin, Anowarul; Leblanc, Gerard; Kaback, H Ronald; Guan, LanNature communications2014300924389923
Crystallization of the large membrane protein complex photosystem I in a microfluidic channel.Abdallah, Bahige G; Kupitz, Christopher; Fromme, Petra; Ros, AlexandraACS nano2013 Dec 2310534-4324191698
Serial femtosecond crystallography of G protein-coupled receptors.Liu, Wei; Wacker, Daniel; Gati, Cornelius; Han, Gye Won; James, Daniel; Wang, Dingjie; Nelson, Garrett; Weierstall, Uwe; Katritch, Vsevolod; Barty, Anton; Zatsepin, Nadia A; Li, Dianfan; Messerschmidt, Marc; Boutet, Sebastien; Williams, Garth J; Koglin, JScience (New York, N.Y.)2013 Dec 201521-424357322
Evolutionary mix-and-match with MFS transporters II.Madej, M Gregor; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2013 Dec 10E4831-824259711
A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-* implicated in Alzheimer's disease.Savelieff, Masha G; Liu, Yuzhong; Senthamarai, Russell R P; Korshavn, Kyle J; Lee, Hyuck Jin; Ramamoorthy, Ayyalusamy; Lim, Mi HeeChemical communications (Cambridge, England)2013 Dec 10NULL24326305
Shortening spin-lattice relaxation using a copper-chelated lipid at low-temperatures - A magic angle spinning solid-state NMR study on a membrane-bound protein.Yamamoto, Kazutoshi; Caporini, Marc A; Im, Sangchoul; Waskell, Lucy; Ramamoorthy, AyyalusamyJournal of magnetic resonance (San Diego, Calif. : 1997)2013 Dec175-8124246881
Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.Pak, John Edward; Ekende, Elisabeth Ngonlong; Kifle, Efrem G; O'Connell 3rd, Joseph Daniel; De Angelis, Fabien; Tessema, Meseret B; Derfoufi, Kheiro-Mouna; Robles-Colmenares, Yaneth; Robbins, Rebecca A; Goormaghtigh, Erik; Vandenbussche, Guy; Stroud, RobeProceedings of the National Academy of Sciences of the United States of America2013 Nov 1218484-924173033
Novel tripod amphiphiles for membrane protein analysis.Chae, Pil Seok; Kruse, Andrew C; Gotfryd, Kamil; Rana, Rohini R; Cho, Kyung Ho; Rasmussen, Soren G F; Bae, Hyoung Eun; Chandra, Richa; Gether, Ulrik; Guan, Lan; Kobilka, Brian K; Loland, Claus J; Byrne, Bernadette; Gellman, Samuel HChemistry (Weinheim an der Bergstrasse, Germany)2013 Nov 1115645-5124123610
Cytochrome-P450-cytochrome-b5 interaction in a membrane environment changes 15N chemical shift anisotropy tensors.Pandey, Manoj Kumar; Vivekanandan, Subramanian; Ahuja, Shivani; Huang, Rui; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, AyyalusamyThe journal of physical chemistry. B2013 Nov 713851-6024107224
The silent codon change I507-ATC->ATT contributes to the severity of the ýýF508 CFTR channel dysfunction.Lazrak, Ahmed; Fu, Lianwu; Bali, Vedrana; Bartoszewski, Rafal; Rab, Andras; Havasi, Viktoria; Keiles, Steve; Kappes, John; Kumar, Ranjit; Lefkowitz, Elliot; Sorscher, Eric J; Matalon, Sadis; Collawn, James F; Bebok, ZsuzsannaFASEB journal : official publication of the Federation of American Societies for Experimental Biology2013 Nov4630-4523907436
Impact of histidine residues on the transmembrane helices of viroporins.Wang, Yan; Park, Sang Ho; Tian, Ye; Opella, Stanley JMolecular membrane biology2013 Nov360-924102567
Back to the future: recombinant polyclonal antibody therapeutics.Wang, Xian-Zhe; Coljee, Vincent W; Maynard, Jennifer ACurrent opinion in chemical engineering2013 Nov405-41524443710
Dielectrophoretic sorting of membrane protein nanocrystals.Abdallah, Bahige G; Chao, Tzu-Chiao; Kupitz, Christopher; Fromme, Petra; Ros, AlexandraACS nano2013 Oct 229129-3724004002
(1)H, (13)C and (15)N resonance assignments for the full-length mammalian cytochrome b5 in a membrane environment.Vivekanandan, Subramanian; Ahuja, Shivani; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, AyyalusamyBiomolecular NMR assignments2013 Oct 9NULL24105099
Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs.Didenko, Tatiana; Liu, Jeffrey J; Horst, Reto; Stevens, Raymond C; Wuthrich, KurtCurrent opinion in structural biology2013 Oct740-723932201
YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery.Zhu, Lu; Kaback, H Ronald; Dalbey, Ross EThe Journal of biological chemistry2013 Sep 2728180-9423928306
Advanced solid-state NMR approaches for structure determination of membrane proteins and amyloid fibrils.Tang, Ming; Comellas, Gemma; Rienstra, Chad MAccounts of chemical research2013 Sep 172080-823659727
Membrane protein structure determination in membrana.Ding, Yi; Yao, Yong; Marassi, Francesca MAccounts of chemical research2013 Sep 172182-9024041243
The N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and Membranes.Skjevik, Age Aleksander; Mileni, Mauro; Baumann, Anne; Halskau, Oyvind; Teigen, Knut; Stevens, Raymond C; Martinez, AuroraJournal of molecular biology2013 Sep 17NULL24055376
The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.Jurgens, Maike C; Voros, Judit; Rautureau, Gilles J P; Shepherd, Dale A; Pye, Valerie E; Muldoon, Jimmy; Johnson, Christopher M; Ashcroft, Alison E; Freund, Stefan M V; Ferguson, NeilNature chemical biology2013 Sep540-723851574
Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles.Yamamoto, Kazutoshi; Gildenberg, Melissa; Ahuja, Shivani; Im, Sang-Choul; Pearcy, Paige; Waskell, Lucy; Ramamoorthy, AyyalusamyScientific reports2013 Aug 30255623989972
In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots.Panthani, Matthew G; Khan, Tarik A; Reid, Dariya K; Hellebusch, Daniel J; Rasch, Michael R; Maynard, Jennifer A; Korgel, Brian ANano letters2013 Aug 9NULL23915166
Improved production of membrane proteins in Escherichia coli by selective codon substitutions.Norholm, Morten H H; Toddo, Stephen; Virkki, Minttu T I; Light, Sara; von Heijne, Gunnar; Daley, Daniel OFEBS letters2013 Aug 22352-823769986
Advances in NMR structures of integral membrane proteins.Maslennikov, Innokentiy; Choe, SenyonCurrent opinion in structural biology2013 Aug555-6223721747
Engineered nanostructured ýý-sheet peptides protect membrane proteins.Tao, Houchao; Lee, Sung Chang; Moeller, Arne; Roy, Rituparna Sinha; Siu, Fai Yiu; Zimmermann, Jorg; Stevens, Raymond C; Potter, Clinton S; Carragher, Bridget; Zhang, QinghaiNature methods2013 Aug759-6123817067
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data.Ahuja, Shivani; Jahr, Nicole; Im, Sang-Choul; Vivekanandan, Subramanian; Popovych, Nataliya; Le Clair, Stephanie V; Huang, Rui; Soong, Ronald; Xu, Jiadi; Yamamoto, Kazutoshi; Nanga, Ravi P; Bridges, Angela; Waskell, Lucy; Ramamoorthy, AyyalusamyThe Journal of biological chemistry2013 Jul 2622080-9523709268
Structure of the human glucagon class B G-protein-coupled receptor.Siu, Fai Yiu; He, Min; de Graaf, Chris; Han, Gye Won; Yang, Dehua; Zhang, Zhiyun; Zhou, Caihong; Xu, Qingping; Wacker, Daniel; Joseph, Jeremiah S; Liu, Wei; Lau, Jesper; Cherezov, Vadim; Katritch, Vsevolod; Wang, Ming-Wei; Stevens, Raymond CNature2013 Jul 25444-923863937
Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance.Cook, Gabriel A; Dawson, Lindsay A; Tian, Ye; Opella, Stanley JBiochemistry2013 Jul 24NULL23841474
Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective.Preininger, Anita M; Meiler, Jens; Hamm, Heidi EJournal of molecular biology2013 Jul 102288-9823602809
Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase.Li, Dianfan; Shah, Syed T A; Caffrey, MartinCrystal growth & design2013 Jul 32846-285723956688
Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline.Madden, Jeremy T; Toth, Scott J; Dettmar, Christopher M; Newman, Justin A; Oglesbee, Robert A; Hedderich, Hartmut G; Everly, R Michael; Becker, Michael; Ronau, Judith A; Buchanan, Susan K; Cherezov, Vadim; Morrow, Marie E; Xu, Shenglan; Ferguson, Dale; MaJournal of synchrotron radiation2013 Jul 1531-4023765294
Crystallographic data processing for free-electron laser sources.White, Thomas A; Barty, Anton; Stellato, Francesco; Holton, James M; Kirian, Richard A; Zatsepin, Nadia A; Chapman, Henry NActa crystallographica. Section D, Biological crystallography2013 Jul1231-4023793149
Thermostabilisation of the serotonin transporter in a cocaine-bound conformation.Abdul-Hussein, Saba; Andrell, Juni; Tate, Christopher GJournal of molecular biology2013 Jun 262198-20723706649
The Structure of the Mercury Transporter MerF in Phospholipid Bilayers: A Large Conformational Rearrangement Results from N-Terminal Truncation.Lu, George J; Tian, Ye; Vora, Nemil; Marassi, Francesca M; Opella, Stanley JJournal of the American Chemical Society2013 Jun 269299-30223763519
Membrane disordering is not sufficient for membrane permeabilization by islet amyloid polypeptide: studies of IAPP(20-29) fragments.Brender, Jeffrey R; Heyl, Deborah L; Samisetti, Shyamprasad; Kotler, Samuel A; Osborne, Joshua M; Pesaru, Ranadheer R; Ramamoorthy, AyyalusamyPhysical chemistry chemical physics : PCCP2013 Jun 218908-1523493863
2D 1H/1H RFDR and NOESY NMR experiments on a membrane-bound antimicrobial peptide under magic angle spinning.Ramamoorthy, Ayyalusamy; Xu, JiadiThe journal of physical chemistry. B2013 Jun 66693-70023672643
Peptide crystal simulations reveal hidden dynamics.Janowski, Pawel A; Cerutti, David S; Holton, James; Case, David AJournal of the American Chemical Society2013 May 297938-4823631449
Trp replacements for tightly interacting Gly-Gly pairs in LacY stabilize an outward-facing conformation.Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2013 May 288876-8123671103
Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer.Tang, Ming; Nesbitt, Anna E; Sperling, Lindsay J; Berthold, Deborah A; Schwieters, Charles D; Gennis, Robert B; Rienstra, Chad MJournal of molecular biology2013 May 271670-8223416557
Solid-state NMR study of a 41 kDa membrane protein complex DsbA/DsbB.Sperling, Lindsay J; Tang, Ming; Berthold, Deborah A; Nesbitt, Anna E; Gennis, Robert B; Rienstra, Chad MThe journal of physical chemistry. B2013 May 236052-6023527473
Crystal structure of the integral membrane diacylglycerol kinase.Li, Dianfan; Lyons, Joseph A; Pye, Valerie E; Vogeley, Lutz; Aragao, David; Kenyon, Colin P; Shah, Syed T A; Doherty, Christine; Aherne, Margaret; Caffrey, MartinNature2013 May 23521-423676677
Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site.Schifano, Jason M; Edifor, Regina; Sharp, Jared D; Ouyang, Ming; Konkimalla, Arvind; Husson, Robert N; Woychik, Nancy AProceedings of the National Academy of Sciences of the United States of America2013 May 218501-623650345
Structural basis for alternating access of a eukaryotic calcium/proton exchanger.Waight, Andrew B; Pedersen, Bjorn Panyella; Schlessinger, Avner; Bonomi, Massimiliano; Chau, Bryant H; Roe-Zurz, Zygy; Risenmay, Aaron J; Sali, Andrej; Stroud, Robert MNature2013 May 1923685453
Structure of the human smoothened receptor bound to an antitumour agent.Wang, Chong; Wu, Huixian; Katritch, Vsevolod; Han, Gye Won; Huang, Xi-Ping; Liu, Wei; Siu, Fai Yiu; Roth, Bryan L; Cherezov, Vadim; Stevens, Raymond CNature2013 May 16338-4323636324
Structural basis for molecular recognition at serotonin receptors.Wang, Chong; Jiang, Yi; Ma, Jinming; Wu, Huixian; Wacker, Daniel; Katritch, Vsevolod; Han, Gye Won; Liu, Wei; Huang, Xi-Ping; Vardy, Eyal; McCorvy, John D; Gao, Xiang; Zhou, X Edward; Melcher, Karsten; Zhang, Chenghai; Bai, Fang; Yang, Huaiyu; Yang, LinliScience (New York, N.Y.)2013 May 3610-423519210
Structural features for functional selectivity at serotonin receptors.Wacker, Daniel; Wang, Chong; Katritch, Vsevolod; Han, Gye Won; Huang, Xi-Ping; Vardy, Eyal; McCorvy, John D; Jiang, Yi; Chu, Meihua; Siu, Fai Yiu; Liu, Wei; Xu, H Eric; Cherezov, Vadim; Roth, Bryan L; Stevens, Raymond CScience (New York, N.Y.)2013 May 3615-923519215
Alternate pathways for NADH oxidation in Thermus thermophilus using type 2 NADH dehydrogenases.Venkatakrishnan, Padmaja; Lencina, Andrea M; Schurig-Briccio, Lici A; Gennis, Robert BBiological chemistry2013 May667-7623370906
Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.Kissick, David J; Dettmar, Christopher M; Becker, Michael; Mulichak, Anne M; Cherezov, Vadim; Ginell, Stephan L; Battaile, Kevin P; Keefe, Lisa J; Fischetti, Robert F; Simpson, Garth JActa crystallographica. Section D, Biological crystallography2013 May843-5123633594
Lipid Composition-Dependent Membrane Fragmentation and Pore-Forming Mechanisms of Membrane Disruption by Pexiganan (MSI-78).Lee, Dong-Kuk; Brender, Jeffrey R; Sciacca, Michele F M; Krishnamoorthy, Janarthanan; Yu, Changsu; Ramamoorthy, AyyalusamyBiochemistry2013 Apr 2923590672
Crystal structure of a eukaryotic phosphate transporter.Pedersen, Bjorn P; Kumar, Hemant; Waight, Andrew B; Risenmay, Aaron J; Roe-Zurz, Zygy; Chau, Bryant H; Schlessinger, Avner; Bonomi, Massimiliano; Harries, William; Sali, Andrej; Johri, Atul K; Stroud, Robert MNature2013 Apr 25533-623542591
Evolutionary mix-and-match with MFS transporters.Madej, M Gregor; Dang, Shangyu; Yan, Nieng; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2013 Apr 95870-423530251
Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization.Chae, Pil Seok; Wander, Marc J; Cho, Kyung Ho; Laible, Philip D; Gellman, Samuel HMolecular bioSystems2013 Apr 5626-923377371
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.Lee, Sung Chang; Bennett, Brad C; Hong, Wen-Xu; Fu, Yu; Baker, Kent A; Marcoux, Julien; Robinson, Carol V; Ward, Andrew B; Halpert, James R; Stevens, Raymond C; Stout, Charles David; Yeager, Mark J; Zhang, QinghaiProceedings of the National Academy of Sciences of the United States of America2013 Mar 26E1203-1123479627
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.Chae, Pil Seok; Rana, Rohini R; Gotfryd, Kamil; Rasmussen, Soren G F; Kruse, Andrew C; Cho, Kyung Ho; Capaldi, Stefano; Carlsson, Emil; Kobilka, Brian; Loland, Claus J; Gether, Ulrik; Banerjee, Surajit; Byrne, Bernadette; Lee, John K; Gellman, Samuel HChemical communications (Cambridge, England)2013 Mar 212287-923165475
Resolution of oligomeric species during the aggregation of Aýý1-40 using (19)F NMR.Suzuki, Yuta; Brender, Jeffrey R; Soper, Molly T; Krishnamoorthy, Janarthanan; Zhou, Yunlong; Ruotolo, Brandon T; Kotov, Nicholas A; Ramamoorthy, Ayyalusamy; Marsh, E Neil GBiochemistry2013 Mar 191903-1223445400
Integral membrane proteins and bilayer proteomics.Whitelegge, Julian PAnalytical chemistry2013 Mar 52558-6823301778
Linking receptor activation to changes in Sw I and II of Gýý proteins.Hamm, Heidi E; Kaya, Ali I; Gilbert 3rd, James A; Preininger, Anita MJournal of structural biology2013 Mar 423466875
Characterization of the Type III sulfide:quinone oxidoreductase from Caldivirga maquilingensis and its membrane binding.Lencina, Andrea M; Ding, Ziqiao; Schurig-Briccio, Lici A; Gennis, Robert BBiochimica et biophysica acta2013 Mar266-7523103448
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions.Seidel, Susanne A I; Dijkman, Patricia M; Lea, Wendy A; van den Bogaart, Geert; Jerabek-Willemsen, Moran; Lazic, Ana; Joseph, Jeremiah S; Srinivasan, Prakash; Baaske, Philipp; Simeonov, Anton; Katritch, Ilia; Melo, Fernando A; Ladbury, John E; Schreiber, Methods (San Diego, Calif.)2013 Mar301-1523270813
Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames.Coote, Paul; Arthanari, Haribabu; Yu, Tsyr-Yan; Natarajan, Amarnath; Wagner, Gerhard; Khaneja, NavinJournal of biomolecular NMR2013 Mar291-30223420125
Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins.Hagn, Franz; Etzkorn, Manuel; Raschle, Thomas; Wagner, GerhardJournal of the American Chemical Society2013 Feb 61919-2523294159
Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy.Coudray, Nicolas; Valvo, Salvatore; Hu, Minghui; Lasala, Ralph; Kim, Changki; Vink, Martin; Zhou, Ming; Provasi, Davide; Filizola, Marta; Tao, Juoehi; Fang, Jia; Penczek, Pawel A; Ubarretxena-Belandia, Iban; Stokes, David LProceedings of the National Academy of Sciences of the United States of America2013 Feb 52140-523341604
Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans.Thaker, Tarjani M; Tanabe, Mikio; Fowler, Matthew L; Preininger, Anita M; Ingram-Smith, Cheryl; Smith, Kerry S; Iverson, T MJournal of structural biology2013 Feb185-923159802
Engineering visual arrestin-1 with special functional characteristics.Vishnivetskiy, Sergey A; Chen, Qiuyan; Palazzo, Maria C; Brooks, Evan K; Altenbach, Christian; Iverson, Tina M; Hubbell, Wayne L; Gurevich, Vsevolod VThe Journal of biological chemistry2013 Feb 13394-40523250748
When detergent meets bilayer: birth and coming of age of lipid bicelles.Durr, Ulrich H N; Soong, Ronald; Ramamoorthy, AyyalusamyProgress in nuclear magnetic resonance spectroscopy2013 Feb1-2223465641
Quantum chemical calculations of amide-15N chemical shift anisotropy tensors for a membrane-bound cytochrome-b5.Pandey, Manoj Kumar; Ramamoorthy, AyyalusamyThe journal of physical chemistry. B2013 Jan 24859-6723268659
Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin.Zhuang, Tiandi; Chen, Qiuyan; Cho, Min-Kyu; Vishnivetskiy, Sergey A; Iverson, Tina M; Gurevich, Vsevolod V; Sanders, Charles RProceedings of the National Academy of Sciences of the United States of America2013 Jan 15942-723277586
Correction to CHOBIMALT: A Cholesterol-Based Detergent.Howell, Stanley C; Fraser, Niall J; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Breyer, Richard M; Sanders, Charles RBiochemistry2013 Jan 1544523289860
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.Redecke, Lars; Nass, Karol; DePonte, Daniel P; White, Thomas A; Rehders, Dirk; Barty, Anton; Stellato, Francesco; Liang, Mengning; Barends, Thomas R M; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Aquila, Andrew; Arnlund, Science (New York, N.Y.)2013 Jan 11227-3023196907
ýý2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements.Horst, Reto; Stanczak, Pawel; Stevens, Raymond C; Wuthrich, KurtAngewandte Chemie (International ed. in English)2013 Jan 2331-523097212
Modeling, docking, and fitting of atomic structures to 3D maps from cryo-electron microscopy.Allen, Gregory S; Stokes, David LMethods in molecular biology (Clifton, N.J.)2013229-4123132064
High-throughput methods for electron crystallography.Stokes, David L; Ubarretxena-Belandia, Iban; Gonen, Tamir; Engel, AndreasMethods in molecular biology (Clifton, N.J.)2013273-9623132066
An artificial neural network approach to improving the correlation between protein energetics and the backbone structure.Fawcett, Timothy M; Irausquin, Stephanie J; Simin, Mikhail; Valafar, HomayounProteomics2013 Jan230-823184572
MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues.MacKinnon, Neil; Somashekar, Bagganahalli S; Tripathi, Pratima; Ge, Wencheng; Rajendiran, Thekkelnaycke M; Chinnaiyan, Arul M; Ramamoorthy, AyyalusamyJournal of magnetic resonance (San Diego, Calif. : 1997)2013 Jan93-923232331
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.Stevens, Raymond C; Cherezov, Vadim; Katritch, Vsevolod; Abagyan, Ruben; Kuhn, Peter; Rosen, Hugh; Wuthrich, KurtNature reviews. Drug discovery2013 Jan25-3423237917
Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels.Schlegel, Susan; Rujas, Edurne; Ytterberg, Anders Jimmy; Zubarev, Roman A; Luirink, Joen; de Gier, Jan-WillemMicrobial cell factories20132423497240
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.Rosen, Hugh; Stevens, Raymond C; Hanson, Michael; Roberts, Edward; Oldstone, Michael B AAnnual review of biochemistry2013637-6223527695
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases.Riley, B E; Lougheed, J C; Callaway, K; Velasquez, M; Brecht, E; Nguyen, L; Shaler, T; Walker, D; Yang, Y; Regnstrom, K; Diep, L; Zhang, Z; Chiou, S; Bova, M; Artis, D R; Yao, N; Baker, J; Yednock, T; Johnston, J ANature communications2013198223770887
Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping.Hong, Heedeok; Chang, Yu-Chu; Bowie, James UMethods in molecular biology (Clifton, N.J.)201337-5623975771
Membrane protein structure determination: back to the membrane.Yao, Yong; Ding, Yi; Tian, Ye; Opella, Stanley J; Marassi, Francesca MMethods in molecular biology (Clifton, N.J.)2013145-5823975776
Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy.Yamamoto, Kazutoshi; Durr, Ulrich H N; Xu, Jiadi; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, AyyalusamyScientific reports2013253823985776
Optimizing E. coli-based membrane protein production using Lemo21(DE3) and GFP-fusions.Hjelm, Anna; Schlegel, Susan; Baumgarten, Thomas; Klepsch, Mirjam; Wickstrom, David; Drew, David; de Gier, Jan-WillemMethods in molecular biology (Clifton, N.J.)2013381-40023996190
High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane.Zook, James D; Molugu, Trivikram R; Jacobsen, Neil E; Lin, Guangxin; Soll, Jurgen; Cherry, Brian R; Brown, Michael F; Fromme, PetraPloS one2013e7811624205117
Using macromolecular-crystallography beamline and microfluidic platform for small-angle diffraction studies of lipidic matrices for membrane-protein crystallization.Kondrashkina, E; Khvostichenko, D S; Perry, S L; Von Osinski, J; Kenis, P J A; Brister, KJournal of physics. Conference series2013NULL24260038
Three-dimensional localization of the ýý and ýý subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel.Szpyt, John; Lorenzon, Nancy; Perez, Claudio F; Norris, Ethan; Allen, Paul D; Beam, Kurt G; Samso, MontserratThe Journal of biological chemistry2012 Dec 2143853-6123118233
Organization of the influenza virus replication machinery.Moeller, Arne; Kirchdoerfer, Robert N; Potter, Clinton S; Carragher, Bridget; Wilson, Ian AScience (New York, N.Y.)2012 Dec 211631-423180774
Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes.Santos, Jose S; Asmar-Rovira, Guillermo A; Han, Gye Won; Liu, Wei; Syeda, Ruhma; Cherezov, Vadim; Baker, Kent A; Stevens, Raymond C; Montal, MauricioThe Journal of biological chemistry2012 Dec 1443063-7023095758
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Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes?McHenry, Austin J; Sciacca, Michele F M; Brender, Jeffrey R; Ramamoorthy, AyyalusamyBiochimica et biophysica acta2012 Dec3019-2422885355
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Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target.Tripathi, Pratima; Kamarajan, Pachiyappan; Somashekar, Bagganahalli S; MacKinnon, Neil; Chinnaiyan, Arul M; Kapila, Yvonne L; Rajendiran, Thekkelnaycke M; Ramamoorthy, AyyalusamyThe international journal of biochemistry & cell biology2012 Nov1852-6122743333
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Two-step mechanism of membrane disruption by Aýý through membrane fragmentation and pore formation.Sciacca, Michele F M; Kotler, Samuel A; Brender, Jeffrey R; Chen, Jennifer; Lee, Dong-kuk; Ramamoorthy, AyyalusamyBiophysical journal2012 Aug 22702-1022947931
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Facile backbone structure determination of human membrane proteins by NMR spectroscopy.Klammt, Christian; Maslennikov, Innokentiy; Bayrhuber, Monika; Eichmann, Cedric; Vajpai, Navratna; Chiu, Ellis Jeremy Chua; Blain, Katherine Y; Esquivies, Luis; Kwon, June Hyun Jung; Balana, Bartosz; Pieper, Ursula; Sali, Andrej; Slesinger, Paul A; KwiatkNature methods2012 Aug834-922609626
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Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies.Tao, Houchao; Fu, Yu; Thompson, Aaron; Lee, Sung Chang; Mahoney, Nicholas; Stevens, Raymond C; Zhang, QinghaiLangmuir : the ACS journal of surfaces and colloids2012 Jul 3111173-8122780816
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.Chae, Pil Seok; Rasmussen, Soren G F; Rana, Rohini R; Gotfryd, Kamil; Kruse, Andrew C; Manglik, Aashish; Cho, Kyung Ho; Nurva, Shailika; Gether, Ulrik; Guan, Lan; Loland, Claus J; Byrne, Bernadette; Kobilka, Brian K; Gellman, Samuel HChemistry (Weinheim an der Bergstrasse, Germany)2012 Jul 279485-9022730191
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High-resolution protein structure determination by serial femtosecond crystallography.Boutet, Sebastien; Lomb, Lukas; Williams, Garth J; Barends, Thomas R M; Aquila, Andrew; Doak, R Bruce; Weierstall, Uwe; DePonte, Daniel P; Steinbrener, Jan; Shoeman, Robert L; Messerschmidt, Marc; Barty, Anton; White, Thomas A; Kassemeyer, Stephan; KirianScience (New York, N.Y.)2012 Jul 20362-422653729
Structural basis for allosteric regulation of GPCRs by sodium ions.Liu, Wei; Chun, Eugene; Thompson, Aaron A; Chubukov, Pavel; Xu, Fei; Katritch, Vsevolod; Han, Gye Won; Roth, Christopher B; Heitman, Laura H; IJzerman, Adriaan P; Cherezov, Vadim; Stevens, Raymond CScience (New York, N.Y.)2012 Jul 13232-622798613
Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis.Fairman, James W; Dautin, Nathalie; Wojtowicz, Damian; Liu, Wei; Noinaj, Nicholas; Barnard, Travis J; Udho, Eshwar; Przytycka, Teresa M; Cherezov, Vadim; Buchanan, Susan KStructure (London, England : 1993)2012 Jul 31233-4322658748
Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter.Varrin-Doyer, Michel; Spencer, Collin M; Schulze-Topphoff, Ulf; Nelson, Patricia A; Stroud, Robert M; Cree, Bruce A C; Zamvil, Scott SAnnals of neurology2012 Jul53-6422807325
Determination of 15N chemical shift anisotropy from a membrane-bound protein by NMR spectroscopy.Pandey, Manoj Kumar; Vivekanandan, Subramanian; Ahuja, Shivani; Pichumani, Kumar; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, AyyalusamyThe journal of physical chemistry. B2012 Jun 217181-922620865
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The Skp chaperone helps fold soluble proteins in vitro by inhibiting aggregation.Entzminger, Kevin C; Chang, Christine; Myhre, Ryan O; McCallum, Katie C; Maynard, Jennifer ABiochemistry2012 Jun 194822-3422650963
Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solubilized membrane protein OmpX.Horst, Reto; Stanczak, Pawel; Serrano, Pedro; Wuthrich, KurtThe journal of physical chemistry. B2012 Jun 146775-8022335573
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Structure of the human ýý-opioid receptor in complex with JDTic.Wu, Huixian; Wacker, Daniel; Mileni, Mauro; Katritch, Vsevolod; Han, Gye Won; Vardy, Eyal; Liu, Wei; Thompson, Aaron A; Huang, Xi-Ping; Carroll, F Ivy; Mascarella, S Wayne; Westkaemper, Richard B; Mosier, Philip D; Roth, Bryan L; Cherezov, Vadim; Stevens,Nature2012 May 17327-3222437504
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.Thompson, Aaron A; Liu, Wei; Chun, Eugene; Katritch, Vsevolod; Wu, Huixian; Vardy, Eyal; Huang, Xi-Ping; Trapella, Claudio; Guerrini, Remo; Calo, Girolamo; Roth, Bryan L; Cherezov, Vadim; Stevens, Raymond CNature2012 May 17395-922596163
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Engineering genes for predictable protein expression.Gustafsson, Claes; Minshull, Jeremy; Govindarajan, Sridhar; Ness, Jon; Villalobos, Alan; Welch, MarkProtein expression and purification2012 May37-4622425659
Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines.Ohsfeldt, Erika; Huang, Szu-Han; Baycin-Hizal, Deniz; Kristoffersen, Linda; Le, Thuy-My T; Li, Edwin; Hristova, Kalina; Betenbaugh, Michael JBiotechnology and applied biochemistry2012 May-Jun155-6223586824
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Lipid dynamics and protein-lipid interactions in 2D crystals formed with the ýý-barrel integral membrane protein VDAC1.Eddy, Matthew T; Ong, Ta-Chung; Clark, Lindsay; Teijido, Oscar; van der Wel, Patrick C A; Garces, Robert; Wagner, Gerhard; Rostovtseva, Tatiana K; Griffin, Robert GJournal of the American Chemical Society2012 Apr 116375-8722435461
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Manipulating the genetic code for membrane protein production: what have we learnt so far?Norholm, Morten H H; Light, Sara; Virkki, Minttu T I; Elofsson, Arne; von Heijne, Gunnar; Daley, Daniel OBiochimica et biophysica acta2012 Apr1091-621884679
Heparan sulfate chains of syndecan-1 regulate ectodomain shedding.Ramani, Vishnu C; Pruett, Pamela S; Thompson, Camilla A; DeLucas, Lawrence D; Sanderson, Ralph DThe Journal of biological chemistry2012 Mar 239952-6122298773
Evidence for an intermediate conformational state of LacY.Jiang, Xiaoxu; Guan, Lan; Zhou, Yonggang; Hong, Wen-Xu; Zhang, Qinghai; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2012 Mar 20E698-70422355148
Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation.Yu, Michelle A; Egawa, Tsuyoshi; Shinzawa-Itoh, Kyoko; Yoshikawa, Shinya; Guallar, Victor; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary JJournal of the American Chemical Society2012 Mar 144753-6122296274
Biased signaling pathways in ýý2-adrenergic receptor characterized by 19F-NMR.Liu, Jeffrey J; Horst, Reto; Katritch, Vsevolod; Stevens, Raymond C; Wuthrich, KurtScience (New York, N.Y.)2012 Mar 21106-1022267580
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Overexpressing human membrane proteins in stably transfected and clonal human embryonic kidney 293S cells.Chaudhary, Sarika; Pak, John E; Gruswitz, Franz; Sharma, Vinay; Stroud, Robert MNature protocols2012 Mar453-6622322218
Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics.Im, Hyungsoon; Sutherland, Jamie N; Maynard, Jennifer A; Oh, Sang-HyunAnalytical chemistry2012 Feb 211941-722235895
Crystal structure of a lipid G protein-coupled receptor.Hanson, Michael A; Roth, Christopher B; Jo, Euijung; Griffith, Mark T; Scott, Fiona L; Reinhart, Greg; Desale, Hans; Clemons, Bryan; Cahalan, Stuart M; Schuerer, Stephan C; Sanna, M Germana; Han, Gye Won; Kuhn, Peter; Rosen, Hugh; Stevens, Raymond CScience (New York, N.Y.)2012 Feb 17851-522344443
Restriction enzyme-free construction of random gene mutagenesis libraries in Escherichia coli.Pai, Jen C; Entzminger, Kevin C; Maynard, Jennifer AAnalytical biochemistry2012 Feb 15640-822155067
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Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly.Moeller, Arne; Zhao, Chunxia; Fried, Michael G; Wilson-Kubalek, Elizabeth M; Carragher, Bridget; Whiteheart, Sidney WJournal of structural biology2012 Feb335-4322245547
Time-resolved protein nanocrystallography using an X-ray free-electron laser.Aquila, Andrew; Hunter, Mark S; Doak, R Bruce; Kirian, Richard A; Fromme, Petra; White, Thomas A; Andreasson, Jakob; Arnlund, David; Bajt, Sasa; Barends, Thomas R M; Barthelmess, Miriam; Bogan, Michael J; Bostedt, Christoph; Bottin, Herve; Bozek, John D; Optics express2012 Jan 302706-1622330507
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Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications.McClure, Michelle; DeLucas, Lawrence J; Wilson, Landon; Ray, Marjorie; Rowe, Steven M; Wu, Xiaoyun; Dai, Qun; Hong, Jeong S; Sorscher, Eric J; Kappes, John C; Barnes, StephenProtein engineering, design & selection : PEDS2012 Jan14-Jul22119790
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VITAL NMR: using chemical shift derived secondary structure information for a limited set of amino acids to assess homology model accuracy.Brothers, Michael C; Nesbitt, Anna E; Hallock, Michael J; Rupasinghe, Sanjeewa G; Tang, Ming; Harris, Jason; Baudry, Jerome; Schuler, Mary A; Rienstra, Chad MJournal of biomolecular NMR2012 Jan41-5622183804
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Harvesting and cryo-cooling crystals of membrane proteins grown in lipidic mesophases for structure determination by macromolecular crystallography.Li, Dianfan; Boland, Coilin; Aragao, David; Walsh, Kilian; Caffrey, MartinJournal of visualized experiments : JoVE2012e400122971942
Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339.Roy, Benjamin M; Zhukov, Dmitriy V; Maynard, Jennifer APloS one2012e4758523110081
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Sugar recognition by CscB and LacY.Sugihara, Junichi; Smirnova, Irina; Kasho, Vladimir; Kaback, H RonaldBiochemistry2011 Dec 2711009-1422106930
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Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains.Shah, Manish B; Pascual, Jaime; Zhang, Qinghai; Stout, C David; Halpert, James RMolecular pharmacology2011 Dec1047-5521875942
Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering.Joseph, Jeremiah S; Liu, Wei; Kunken, Joshua; Weiss, Thomas M; Tsuruta, Hiro; Cherezov, VadimMethods (San Diego, Calif.)2011 Dec342-921903166
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Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells.Chaudhary, Sarika; Pak, John E; Pedersen, Bjorn P; Bang, Lois J; Zhang, Liye B; Ngaw, Samantha M M; Green, Raissa G; Sharma, Vinay; Stroud, Robert MMethods (San Diego, Calif.)2011 Dec273-8021925269
Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy.Milazzo, Anna-Clare; Cheng, Anchi; Moeller, Arne; Lyumkis, Dmitry; Jacovetty, Erica; Polukas, James; Ellisman, Mark H; Xuong, Nguyen-Huu; Carragher, Bridget; Potter, Clinton SJournal of structural biology2011 Dec404-821933715
Investigating the intermediates in the reaction of ribonucleoside triphosphate reductase from Lactobacillus leichmannii: An application of HF EPR-RFQ technology.Manzerova, Julia; Krymov, Vladimir; Gerfen, Gary JJournal of magnetic resonance (San Diego, Calif. : 1997)2011 Dec32-4521944735
Membrane interaction of Pasteurella multocida toxin involves sphingomyelin.Brothers, Michael C; Ho, Mengfei; Maharjan, Ram; Clemons, Nathan C; Bannai, Yuka; Waites, Mark A; Faulkner, Melinda J; Kuhlenschmidt, Theresa B; Kuhlenschmidt, Mark S; Blanke, Steven R; Rienstra, Chad M; Wilson, Brenda AThe FEBS journal2011 Dec4633-4821951695
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New amphiphiles for membrane protein structural biology.Zhang, Qinghai; Tao, Houchao; Hong, Wen-XuMethods (San Diego, Calif.)2011 Dec318-2321958988
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A helical processing pipeline for EM structure determination of membrane proteins.Fisher, Lauren S; Ward, Andrew; Milligan, Ronald A; Unwin, Nigel; Potter, Clinton S; Carragher, BridgetMethods (San Diego, Calif.)2011 Dec350-6221964395
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles.Thompson, Aaron A; Liu, Jeffrey J; Chun, Eugene; Wacker, Daniel; Wu, Huixian; Cherezov, Vadim; Stevens, Raymond CMethods (San Diego, Calif.)2011 Dec310-722041719
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Interactions of interleukin-8 with the human chemokine receptor CXCR1 in phospholipid bilayers by NMR spectroscopy.Park, Sang Ho; Casagrande, Fabio; Cho, Leah; Albrecht, Lauren; Opella, Stanley JJournal of molecular biology2011 Nov 25194-20322019593
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An active photoreceptor intermediate revealed by in situ photoirradiated solid-state NMR spectroscopy.Tomonaga, Yuya; Hidaka, Tetsurou; Kawamura, Izuru; Nishio, Takudo; Ohsawa, Kazuhiro; Okitsu, Takashi; Wada, Akimori; Sudo, Yuki; Kamo, Naoki; Ramamoorthy, Ayyalusamy; Naito, AkiraBiophysical journal2011 Nov 16L50-222098758
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High-resolution membrane protein structure by joint calculations with solid-state NMR and X-ray experimental data.Tang, Ming; Sperling, Lindsay J; Berthold, Deborah A; Schwieters, Charles D; Nesbitt, Anna E; Nieuwkoop, Andrew J; Gennis, Robert B; Rienstra, Chad MJournal of biomolecular NMR2011 Nov227-3321938394
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR.Horst, Reto; Horwich, Arthur L; Wuthrich, KurtJournal of the American Chemical Society2011 Oct 1916354-721919531
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Radical formation in cytochrome c oxidase.Yu, Michelle A; Egawa, Tsuyoshi; Shinzawa-Itoh, Kyoko; Yoshikawa, Shinya; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary JBiochimica et biophysica acta2011 Oct1295-30421718686
A reference map of the membrane proteome of Enterococcus faecalis.Maddalo, Gianluca; Chovanec, Peter; Stenberg-Bruzell, Filippa; Nielsen, Hailyn V; Jensen-Seaman, Michael I; Ilag, Leopold L; Kline, Kimberly A; Daley, Daniel OProteomics2011 Oct3935-4121800426
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke.Chappie, Joshua S; Mears, Jason A; Fang, Shunming; Leonard, Marilyn; Schmid, Sandra L; Milligan, Ronald A; Hinshaw, Jenny E; Dyda, FredCell2011 Sep 30209-2221962517
Crystal structure of the ýý2 adrenergic receptor-Gs protein complex.Rasmussen, Soren G F; DeVree, Brian T; Zou, Yaozhong; Kruse, Andrew C; Chung, Ka Young; Kobilka, Tong Sun; Thian, Foon Sun; Chae, Pil Seok; Pardon, Els; Calinski, Diane; Mathiesen, Jesper M; Shah, Syed T A; Lyons, Joseph A; Caffrey, Martin; Gellman, SamueNature2011 Sep 29549-5521772288
Accessing protein conformational ensembles using room-temperature X-ray crystallography.Fraser, James S; van den Bedem, Henry; Samelson, Avi J; Lang, P Therese; Holton, James M; Echols, Nathaniel; Alber, TomProceedings of the National Academy of Sciences of the United States of America2011 Sep 2716247-5221918110
Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective.Brender, Jeffrey R; Salamekh, Samer; Ramamoorthy, AyyalusamyAccounts of chemical research2011 Sep 25NULL21942864
An early event in the transport mechanism of LacY protein: interaction between helices V and I.Zhou, Yonggang; Madej, M Gregor; Guan, Lan; Nie, Yiling; Kaback, H RonaldThe Journal of biological chemistry2011 Sep 230415-2221730060
Cross-correlations between low-ýý nuclei in solids via a common dipolar bath.Khitrin, Aanatoly K; Xu, Jiadi; Ramamoorthy, AyyalusamyJournal of magnetic resonance (San Diego, Calif. : 1997)2011 Sep95-10121820340
The conformation of bacteriorhodopsin loops in purple membranes resolved by solid-state MAS NMR spectroscopy.Higman, Victoria A; Varga, Krisztina; Aslimovska, Lubica; Judge, Peter J; Sperling, Lindsay J; Rienstra, Chad M; Watts, AnthonyAngewandte Chemie (International ed. in English)2011 Aug 298432-521770003
Total chemical synthesis of biologically active vascular endothelial growth factor.Mandal, Kalyaneswar; Kent, Stephen B HAngewandte Chemie (International ed. in English)2011 Aug 228029-3321744452
In situ structural characterization of a recombinant protein in native Escherichia coli membranes with solid-state magic-angle-spinning NMR.Fu, Riqiang; Wang, Xingsheng; Li, Conggang; Santiago-Miranda, Adriana N; Pielak, Gary J; Tian, FangJournal of the American Chemical Society2011 Aug 1712370-321774553
The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal.Vergis, James M; Wiener, Michael CProtein expression and purification2011 Aug139-4221539919
Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination.Fromme, Petra; Spence, John C HCurrent opinion in structural biology2011 Aug509-1621752635
Lipidic cubic phase technologies for membrane protein structural studies.Cherezov, VadimCurrent opinion in structural biology2011 Aug559-6621775127
Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments.Hong, Heedeok; Bowie, James UJournal of the American Chemical Society2011 Jul 2711389-9821682279
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins.Shaya, David; Kreir, Mohamed; Robbins, Rebecca A; Wong, Stephanie; Hammon, Justus; Bruggemann, Andrea; Minor Jr, Daniel LProceedings of the National Academy of Sciences of the United States of America2011 Jul 2612313-821746903
Solid-State NMR of a Large Membrane Protein by Paramagnetic Relaxation Enhancement.Tang, Ming; Berthold, Deborah A; Rienstra, Chad MThe journal of physical chemistry letters2011 Jul 211836-184121841965
The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase.Kudugunti, Shashi K; Thorsheim, Helen; Yousef, Mohammad S; Guan, Lan; Moridani, Majid YChemico-biological interactions2011 Jul 15243-5621458432
Structure of the human histamine H1 receptor complex with doxepin.Shimamura, Tatsuro; Shiroishi, Mitsunori; Weyand, Simone; Tsujimoto, Hirokazu; Winter, Graeme; Katritch, Vsevolod; Abagyan, Ruben; Cherezov, Vadim; Liu, Wei; Han, Gye Won; Kobayashi, Takuya; Stevens, Raymond C; Iwata, SoNature2011 Jul 765-7021697825
1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples.Lin, Eugene C; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2011 Jul37-4421543244
Molecular determinants of phospholipid synergy in blood clotting.Tavoosi, Narjes; Davis-Harrison, Rebecca L; Pogorelov, Taras V; Ohkubo, Y Zenmei; Arcario, Mark J; Clay, Mary C; Rienstra, Chad M; Tajkhorshid, Emad; Morrissey, James HThe Journal of biological chemistry2011 Jul 123247-5321561861
Nanoscale studies of protein-membrane interactions in blood clotting.Morrissey, J H; Tajkhorshid, E; Rienstra, C MJournal of thrombosis and haemostasis : JTH2011 Jul162-721781251
The crystal structure of the ýý-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function.Miller, Meghan T; Mileni, Mauro; Comoletti, Davide; Stevens, Raymond C; Harel, Michal; Taylor, PalmerStructure (London, England : 1993)2011 Jun 8767-7821620717
Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity.Gay, Sean C; Zhang, Haoming; Wilderman, P Ross; Roberts, Arthur G; Liu, Tong; Li, Sheng; Lin, Hsia-Lien; Zhang, Qinghai; Woods Jr, Virgil L; Stout, C David; Hollenberg, Paul F; Halpert, James RBiochemistry2011 Jun 74903-1121510666
Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition.Chaptal, Vincent; Kwon, Seunghyug; Sawaya, Michael R; Guan, Lan; Kaback, H Ronald; Abramson, JeffProceedings of the National Academy of Sciences of the United States of America2011 Jun 79361-621593407
Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum.Selao, Tiago Toscano; Branca, Rui; Chae, Pil Seok; Lehtio, Janne; Gellman, Samuel H; Rasmussen, Soren G F; Nordlund, Stefan; Noren, AgnetaJournal of proteome research2011 Jun 32703-1421443180
Characterization of the consequences of YidC depletion on the inner membrane proteome of E. coli using 2D blue native/SDS-PAGE.Wickstrom, David; Wagner, Samuel; Simonsson, Per; Pop, Ovidiu; Baars, Louise; Ytterberg, A Jimmy; van Wijk, Klaas J; Luirink, Joen; de Gier, Jan-Willem LJournal of molecular biology2011 Jun 3124-3521497606
Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy.Cook, Gabriel A; Opella, Stanley JBiochimica et biophysica acta2011 Jun1448-5320727850
Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies.Wang, Xingsheng; Gill Jr, Richard L; Zhu, Qin; Tian, FangProtein expression and purification2011 Jun224-3021320603
Crystallizing membrane proteins for structure-function studies using lipidic mesophases.Caffrey, MartinBiochemical Society transactions2011 Jun725-3221599641
Generation of recombinant guinea pig antibody fragments to the human GABAC receptor.Memic, Adnan; Volgina, Veronica V; Gussin, Helene A; Pepperberg, David R; Kay, Brian KJournal of immunological methods2011 May 3136-4421362428
Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes.Li, Dianfan; Caffrey, MartinProceedings of the National Academy of Sciences of the United States of America2011 May 248639-4421555546
Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria.Xu, Yongbin; Lee, Minho; Moeller, Arne; Song, Saemee; Yoon, Bo-Young; Kim, Hong-Man; Jun, So-Young; Lee, Kangseok; Ha, Nam-ChulThe Journal of biological chemistry2011 May 2017910-2021454662
Drop-out phagemid vector for switching from phage displayed affinity reagents to expression formats.Pershad, Kritika; Sullivan, Mark A; Kay, Brian KAnalytical biochemistry2011 May 15210-621315061
Conversion of scFv peptide-binding specificity for crystal chaperone development.Pai, Jennifer C; Culver, Jeffrey A; Drury, Jason E; Motani, Rakesh S; Lieberman, Raquel L; Maynard, Jennifer AProtein engineering, design & selection : PEDS2011 May419-2821217145
A proton spin diffusion based solid-state NMR approach for structural studies on aligned samples.Xu, Jiadi; Smith, Pieter E S; Soong, Ronald; Ramamoorthy, AyyalusamyThe journal of physical chemistry. B2011 Apr 284863-7121466219
Coupling efficiency of rhodopsin and transducin in bicelles.Kaya, Ali I; Thaker, Tarjani M; Preininger, Anita M; Iverson, T M; Hamm, Heidi EBiochemistry2011 Apr 193193-20321375271
Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC.Xu, Yongbin; Song, Saemee; Moeller, Arne; Kim, Nahee; Piao, Shunfu; Sim, Se-Hoon; Kang, Mooseok; Yu, Wookyung; Cho, Hyun-Soo; Chang, Iksoo; Lee, Kangseok; Ha, Nam-ChulThe Journal of biological chemistry2011 Apr 1513541-921325274
Structure of an agonist-bound human A2A adenosine receptor.Xu, Fei; Wu, Huixian; Katritch, Vsevolod; Han, Gye Won; Jacobson, Kenneth A; Gao, Zhan-Guo; Cherezov, Vadim; Stevens, Raymond CScience (New York, N.Y.)2011 Apr 15322-721393508
Consequences of the overexpression of a eukaryotic membrane protein, the human KDEL receptor, in Escherichia coli.Klepsch, Mirjam M; Persson, Jan O; de Gier, Jan-Willem LJournal of molecular biology2011 Apr 8532-4221316372
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases.Xu, Fei; Liu, Wei; Hanson, Michael A; Stevens, Raymond C; Cherezov, VadimCrystal growth & design2011 Apr 61193-120121660116
Membrane Protein Crystallization in Lipidic Mesophases. Hosting lipid affects on the crystallization and structure of a transmembrane peptide.Hofer, Nicole; Aragao, David; Lyons, Joseph A; Caffrey, MartinCrystal growth & design2011 Apr 61182-119222933857
Systematic analysis of native membrane protein complexes in Escherichia coli.Maddalo, Gianluca; Stenberg-Bruzell, Filippa; Gotzke, Hansjorg; Toddo, Stephen; Bjorkholm, Patrik; Eriksson, Hanna; Chovanec, Peter; Genevaux, Pierre; Lehtio, Janne; Ilag, Leopold L; Daley, Daniel OJournal of proteome research2011 Apr 11848-5921210718
Straightforward, effective calibration of SPINAL-64 decoupling results in the enhancement of sensitivity and resolution of biomolecular solid-state NMR.Comellas, Gemma; Lopez, Jakob J; Nieuwkoop, Andrew J; Lemkau, Luisel R; Rienstra, Chad MJournal of magnetic resonance (San Diego, Calif. : 1997)2011 Apr131-521296014
A general assignment method for oriented sample (OS) solid-state NMR of proteins based on the correlation of resonances through heteronuclear dipolar couplings in samples aligned parallel and perpendicular to the magnetic field.Lu, George J; Son, Woo Sung; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2011 Apr195-20621316275
Label-free quantification of membrane-ligand interactions using backscattering interferometry.Baksh, Michael M; Kussrow, Amanda K; Mileni, Mauro; Finn, M G; Bornhop, Darryl JNature biotechnology2011 Apr357-6021399645
Solid-state NMR study of the charge-transfer complex between ubiquinone-8 and disulfide bond generating membrane protein DsbB.Tang, Ming; Sperling, Lindsay J; Berthold, Deborah A; Nesbitt, Anna E; Gennis, Robert B; Rienstra, Chad MJournal of the American Chemical Society2011 Mar 304359-6621375236
Atomic view of calcium-induced clustering of phosphatidylserine in mixed lipid bilayers.Boettcher, John M; Davis-Harrison, Rebecca L; Clay, Mary C; Nieuwkoop, Andrew J; Ohkubo, Y Zenmei; Tajkhorshid, Emad; Morrissey, James H; Rienstra, Chad MBiochemistry2011 Mar 292264-7321294564
Local and global dynamics of the G protein-coupled receptor CXCR1.Park, Sang Ho; Casagrande, Fabio; Das, Bibhuti B; Albrecht, Lauren; Chu, Mignon; Opella, Stanley JBiochemistry2011 Mar 292371-8021323370
Site-directed alkylation studies with LacY provide evidence for the alternating access model of transport.Jiang, Xiaoxu; Nie, Yiling; Kaback, H RonaldBiochemistry2011 Mar 151634-4021254783
Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals.Kirian, Richard A; White, Thomas A; Holton, James M; Chapman, Henry N; Fromme, Petra; Barty, Anton; Lomb, Lukas; Aquila, Andrew; Maia, Filipe R N C; Martin, Andrew V; Fromme, Raimund; Wang, Xiaoyu; Hunter, Mark S; Schmidt, Kevin E; Spence, John C HActa crystallographica. Section A, Foundations of crystallography2011 Mar131-4021325716
Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.Tsai, Ah-lim; Wu, Gang; Rogge, Corina E; Lu, Jian-Ming; Peng, Sheng; van der Donk, Wilfred A; Palmer, Graham; Gerfen, Gary J; Kulmacz, Richard JJournal of inorganic biochemistry2011 Mar366-7421421123
Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium.Guan, Lan; Nurva, Shailika; Ankeshwarapu, Siva PThe Journal of biological chemistry2011 Feb 256367-7421148559
Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes.Zhan, Xuanzhi; Gimenez, Luis E; Gurevich, Vsevolod V; Spiller, Benjamin WJournal of molecular biology2011 Feb 25467-7821215759
NdhP and NdhQ: two novel small subunits of the cyanobacterial NDH-1 complex.Nowaczyk, Marc M; Wulfhorst, Hannes; Ryan, Christopher M; Souda, Puneet; Zhang, Huamin; Cramer, William A; Whitelegge, Julian PBiochemistry2011 Feb 221121-421244052
Consequences of depletion of the signal recognition particle in Escherichia coli.Wickstrom, David; Wagner, Samuel; Baars, Louise; Ytterberg, A Jimmy; Klepsch, Mirjam; van Wijk, Klaas J; Luirink, Joen; de Gier, Jan-WillemThe Journal of biological chemistry2011 Feb 114598-60920923772
Femtosecond X-ray protein nanocrystallography.Chapman, Henry N; Fromme, Petra; Barty, Anton; White, Thomas A; Kirian, Richard A; Aquila, Andrew; Hunter, Mark S; Schulz, Joachim; DePonte, Daniel P; Weierstall, Uwe; Doak, R Bruce; Maia, Filipe R N C; Martin, Andrew V; Schlichting, Ilme; Lomb, Lukas; CoNature2011 Feb 373-721293373
Comparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1.Cook, Gabriel A; Zhang, Hua; Park, Sang Ho; Wang, Yan; Opella, Stanley JBiochimica et biophysica acta2011 Feb554-6020727848
RDC derived protein backbone resonance assignment using fragment assembly.Wang, Xingsheng; Tash, Brian; Flanagan, John M; Tian, FangJournal of biomolecular NMR2011 Feb85-9821191805
Evidence for the presence of a critical disulfide bond in the mouse EP3ýý receptor.Downey, Jason D; Sanders, Charles R; Breyer, Richard MProstaglandins & other lipid mediators2011 Feb53-821236356
Structure of a nanobody-stabilized active state of the ýý(2) adrenoceptor.Rasmussen, Soren G F; Choi, Hee-Jung; Fung, Juan Jose; Pardon, Els; Casarosa, Paola; Chae, Pil Seok; Devree, Brian T; Rosenbaum, Daniel M; Thian, Foon Sun; Kobilka, Tong Sun; Schnapp, Andreas; Konetzki, Ingo; Sunahara, Roger K; Gellman, Samuel H; Pautsch,Nature2011 Jan 13175-8021228869
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X-ray diffraction from membrane protein nanocrystals.Hunter, M S; DePonte, D P; Shapiro, D A; Kirian, R A; Wang, X; Starodub, D; Marchesini, S; Weierstall, U; Doak, R B; Spence, J C H; Fromme, PBiophysical journal2011 Jan 5198-20621190672
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Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipids.Plesniak, Leigh A; Mahalakshmi, Radhakrishnan; Rypien, Candace; Yang, Yuan; Racic, Jasmina; Marassi, Francesca MBiochimica et biophysica acta2011 Jan482-920883662
Restrained expression, a method to overproduce toxic membrane proteins by exploiting operator-repressor interactions.Narayanan, Anoop; Ridilla, Marc; Yernool, Dinesh AProtein science : a publication of the Protein Society2011 Jan51-6121031485
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Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen.Li, Dianfan; Lee, Jean; Caffrey, MartinCrystal growth & design2011530-53721743796
High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.Tiefenbrunn, Theresa; Liu, Wei; Chen, Ying; Katritch, Vsevolod; Stout, C David; Fee, James A; Cherezov, VadimPloS one2011e2234821814577
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Statistical treatment of photon/electron counting: extending the linear dynamic range from the dark count rate to saturation.Kissick, David J; Muir, Ryan D; Simpson, Garth JAnalytical chemistry2010 Dec 1510129-3421114249
Elucidation of inositol hexaphosphate and heparin interaction sites and conformational changes in arrestin-1 by solution nuclear magnetic resonance.Zhuang, Tiandi; Vishnivetskiy, Sergey A; Gurevich, Vsevolod V; Sanders, Charles RBiochemistry2010 Dec 1410473-8521050017
Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography.Wilderman, P Ross; Shah, Manish B; Liu, Tong; Li, Sheng; Hsu, Simon; Roberts, Arthur G; Goodlett, David R; Zhang, Qinghai; Woods Jr, Virgil L; Stout, C David; Halpert, James RThe Journal of biological chemistry2010 Dec 338602-1120880847
A high-throughput differential filtration assay to screen and select detergents for membrane proteins.Vergis, James M; Purdy, Michael D; Wiener, Michael CAnalytical biochemistry2010 Dec 11-1120667442
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.Chae, Pil Seok; Rasmussen, Soren G F; Rana, Rohini R; Gotfryd, Kamil; Chandra, Richa; Goren, Michael A; Kruse, Andrew C; Nurva, Shailika; Loland, Claus J; Pierre, Yves; Drew, David; Popot, Jean-Luc; Picot, Daniel; Fox, Brian G; Guan, Lan; Gether, Ulrik; BNature methods2010 Dec1003-821037590
Tandem facial amphiphiles for membrane protein stabilization.Chae, Pil Seok; Gotfryd, Kamil; Pacyna, Jennifer; Miercke, Larry J W; Rasmussen, Soren G F; Robbins, Rebecca A; Rana, Rohini R; Loland, Claus J; Kobilka, Brian; Stroud, Robert; Byrne, Bernadette; Gether, Ulrik; Gellman, Samuel HJournal of the American Chemical Society2010 Dec 116750-221049926
GFT projection NMR spectroscopy for proteins in the solid state.Franks, W Trent; Atreya, Hanudatta S; Szyperski, Thomas; Rienstra, Chad MJournal of biomolecular NMR2010 Dec213-2321052779
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.Pentelute, Brad L; Mandal, Kalyaneswar; Gates, Zachary P; Sawaya, Michael R; Yeates, Todd O; Kent, Stephen B HChemical communications (Cambridge, England)2010 Nov 218174-620877851
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.Wu, Beili; Chien, Ellen Y T; Mol, Clifford D; Fenalti, Gustavo; Liu, Wei; Katritch, Vsevolod; Abagyan, Ruben; Brooun, Alexei; Wells, Peter; Bi, F Christopher; Hamel, Damon J; Kuhn, Peter; Handel, Tracy M; Cherezov, Vadim; Stevens, Raymond CScience (New York, N.Y.)2010 Nov 191066-7120929726
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.Chien, Ellen Y T; Liu, Wei; Zhao, Qiang; Katritch, Vsevolod; Han, Gye Won; Hanson, Michael A; Shi, Lei; Newman, Amy Hauck; Javitch, Jonathan A; Cherezov, Vadim; Stevens, Raymond CScience (New York, N.Y.)2010 Nov 191091-521097933
Polyphosphate exerts differential effects on blood clotting, depending on polymer size.Smith, Stephanie A; Choi, Sharon H; Davis-Harrison, Rebecca; Huyck, Jillian; Boettcher, John; Rienstra, Chad M; Reinstra, Chad M; Morrissey, James HBlood2010 Nov 184353-920709905
Phosphoramidate end labeling of inorganic polyphosphates: facile manipulation of polyphosphate for investigating and modulating its biological activities.Choi, Sharon H; Collins, Julie N R; Smith, Stephanie A; Davis-Harrison, Rebecca L; Rienstra, Chad M; Morrissey, James HBiochemistry2010 Nov 169935-4120957999
Method to measure strong protein-protein interactions in lipid bilayers using a steric trap.Hong, Heedeok; Blois, Tracy M; Cao, Zheng; Bowie, James UProceedings of the National Academy of Sciences of the United States of America2010 Nov 1619802-721041662
CHOBIMALT: a cholesterol-based detergent.Howell, Stanley C; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Breyer, Richard M; Sanders, Charles RBiochemistry2010 Nov 99572-8320919740
Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance.Kijac, Aleksandra; Shih, Amy Y; Nieuwkoop, Andrew J; Schulten, Klaus; Sligar, Stephen G; Rienstra, Chad MBiochemistry2010 Nov 29190-820804175
Simultaneous structure and dynamics of a membrane protein using REDCRAFT: membrane-bound form of Pf1 coat protein.Shealy, Paul; Simin, Mikhail; Park, Sang Ho; Opella, Stanley J; Valafar, HomayounJournal of magnetic resonance (San Diego, Calif. : 1997)2010 Nov8-1620829084
Automated protein resonance assignments of magic angle spinning solid-state NMR spectra of ýý1 immunoglobulin binding domain of protein G (GB1).Moseley, Hunter N B; Sperling, Lindsay J; Rienstra, Chad MJournal of biomolecular NMR2010 Nov123-820931264
Membranes in balance: mechanisms of sphingolipid homeostasis.Breslow, David K; Weissman, Jonathan SMolecular cell2010 Oct 22267-7920965421
Structure of a cation-bound multidrug and toxic compound extrusion transporter.He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu; Zhang, Qinghai; Chang, GeoffreyNature2010 Oct 21991-420861838
Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel .Gay, Sean C; Roberts, Arthur G; Maekawa, Keiko; Talakad, Jyothi C; Hong, Wen-Xu; Zhang, Qinghai; Stout, C David; Halpert, James RBiochemistry2010 Oct 128709-2020815363
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Backbone 1H, 13C and 15N resonance assignments of the extracellular domain of tissue factor.Boettcher, John M; Clay, Mary C; LaHood, Benjamin J; Morrissey, James H; Rienstra, Chad MBiomolecular NMR assignments2010 Oct183-520526825
Expression of neurotransmitter transporters for structural and biochemical studies.Elbaz, Yael; Danieli, Tsafi; Kanner, Baruch I; Schuldiner, ShimonProtein expression and purification2010 Oct152-6020566324
Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography.Banigan, James R; Mandal, Kalyaneswar; Sawaya, Michael R; Thammavongsa, Vilasak; Hendrickx, Antoni P A; Schneewind, Olaf; Yeates, Todd O; Kent, Stephen B HProtein science : a publication of the Protein Society2010 Oct1840-920669184
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Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors.Joseph, Prem Raj B; Sarmiento, Jose M; Mishra, Anurag K; Das, Sandhya T; Garofalo, Roberto P; Navarro, Javier; Rajarathnam, KrishnaThe Journal of biological chemistry2010 Sep 1729262-920630874
Triton X-100 as the "short-chain lipid" improves the magnetic alignment and stability of membrane proteins in phosphatidylcholine bilayers for oriented-sample solid-state NMR spectroscopy.Park, Sang Ho; Opella, Stanley JJournal of the American Chemical Society2010 Sep 1512552-320735058
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations.Singla, Nikhil; Goldgur, Yehuda; Xu, Kai; Paavilainen, Sari; Nikolov, Dimitar B; Himanen, Juha PBiochemical and biophysical research communications2010 Sep 3555-920678482
1H-13C separated local field spectroscopy of uniformly 13C labeled peptides and proteins.Lin, Eugene C; Wu, Chin H; Yang, Yuan; Grant, Christopher V; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2010 Sep105-1120637662
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Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration.Duriseti, Sai; Goetz, David H; Hostetter, Daniel R; LeBeau, Aaron M; Wei, Ying; Craik, Charles SThe Journal of biological chemistry2010 Aug 2726878-8820501655
Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.Wacker, Daniel; Fenalti, Gustavo; Brown, Monica A; Katritch, Vsevolod; Abagyan, Ruben; Cherezov, Vadim; Stevens, Raymond CJournal of the American Chemical Society2010 Aug 2511443-520669948
Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate.Li, Xianghui; Telser, Joshua; Kunz, Ryan C; Hoffman, Brian M; Gerfen, Gary; Ragsdale, Stephen WBiochemistry2010 Aug 176866-7620597483
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Unlocking the eukaryotic membrane protein structural proteome.Lee, John Kyongwon; Stroud, Robert MichaelCurrent opinion in structural biology2010 Aug464-7020739007
Delineating electrogenic reactions during lactose/H+ symport.Garcia-Celma, Juan J; Ploch, Julian; Smirnova, Irina; Kaback, H Ronald; Fendler, KlausBiochemistry2010 Jul 276115-2120568736
Design and folding of [GluA4(ObetaThrB30)]insulin ("ester insulin"): a minimal proinsulin surrogate that can be chemically converted into human insulin.Sohma, Youhei; Hua, Qing-Xin; Whittaker, Jonathan; Weiss, Michael A; Kent, Stephen B HAngewandte Chemie (International ed. in English)2010 Jul 265489-9320509131
Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.Hom, Robert A; Chang, Pei-Yun; Roy, Siddhartha; Musselman, Catherine A; Glass, Karen C; Selezneva, Anna I; Gozani, Or; Ismagilov, Rustem F; Cleary, Michael L; Kutateladze, Tatiana GJournal of molecular biology2010 Jul 9145-5420460131
Automated electron microscopy for evaluating two-dimensional crystallization of membrane proteins.Hu, Minghui; Vink, Martin; Kim, Changki; Derr, Kd; Koss, John; D'Amico, Kevin; Cheng, Anchi; Pulokas, James; Ubarretxena-Belandia, Iban; Stokes, DavidJournal of structural biology2010 Jul102-1020197095
A resonance assignment method for oriented-sample solid-state NMR of proteins.Knox, Robert W; Lu, George J; Opella, Stanley J; Nevzorov, Alexander AJournal of the American Chemical Society2010 Jun 238255-720509649
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Assignment strategies for large proteins by magic-angle spinning NMR: the 21-kDa disulfide-bond-forming enzyme DsbA.Sperling, Lindsay J; Berthold, Deborah A; Sasser, Terry L; Jeisy-Scott, Victoria; Rienstra, Chad MJournal of molecular biology2010 Jun 4268-8220394752
NMR studies of p7 protein from hepatitis C virus.Cook, Gabriel A; Opella, Stanley JEuropean biophysics journal : EBJ2010 Jun1097-10419727701
Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26.Hong, Wen-Xu; Baker, Kent A; Ma, Xingquan; Stevens, Raymond C; Yeager, Mark; Zhang, QinghaiLangmuir : the ACS journal of surfaces and colloids2010 Jun 18690-620232919
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A Plug-Based Microfluidic System for Dispensing Lipidic Cubic Phase (LCP) Material Validated by Crystallizing Membrane Proteins in Lipidic Mesophases.Li, Liang; Fu, Qiang; Kors, Christopher A; Stewart, Lance; Nollert, Peter; Laible, Philip D; Ismagilov, Rustem FMicrofluidics and nanofluidics2010 Jun789-79820473353
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Function of human Rh based on structure of RhCG at 2.1 A.Gruswitz, Franz; Chaudhary, Sarika; Ho, Joseph D; Schlessinger, Avner; Pezeshki, Bobak; Ho, Chi-Min; Sali, Andrej; Westhoff, Connie M; Stroud, Robert MProceedings of the National Academy of Sciences of the United States of America2010 May 259638-4320457942
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A Stochastic Model for Nucleation Kinetics Determination in Droplet-Based Microfluidic Systems.Goh, Limay; Chen, Kejia; Bhamidi, Venkateswarlu; He, Guangwen; Kee, Nicholas C S; Kenis, Paul J A; Zukoski, Charles F; Braatz, Richard DCrystal growth & design2010 May 102515-252120953348
NMR Determination of Protein pK(a) Values in the Solid State.Schmidt, Heather L Frericks; Shah, Gautam J; Sperling, Lindsay J; Rienstra, Chad MThe journal of physical chemistry letters2010 May 41623-162820563223
LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment.Liu, Wei; Hanson, Michael A; Stevens, Raymond C; Cherezov, VadimBiophysical journal2010 Apr 211539-4820409473
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.Tanabe, Mikio; Nimigean, Crina M; Iverson, T MProceedings of the National Academy of Sciences of the United States of America2010 Apr 136811-620351243
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Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel.Teriete, Peter; Yao, Yong; Kolodzik, Adrian; Yu, Jinghua; Song, Houhui; Niederweis, Michael; Marassi, Francesca MBiochemistry2010 Apr 62768-7720199110
The effect of calcium on the conformation of cobalamin transporter BtuB.Luan, Binquan; Carr, Rogan; Caffrey, Martin; Aksimentiev, AlekseiProteins2010 Apr1153-6219927326
EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen.Yu, Michelle A; Egawa, Tsuyoshi; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary JJournal of magnetic resonance (San Diego, Calif. : 1997)2010 Apr213-920056464
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution.Gay, Sean C; Shah, Manish B; Talakad, Jyothi C; Maekawa, Keiko; Roberts, Arthur G; Wilderman, P Ross; Sun, Ling; Yang, Jane Y; Huelga, Stephanie C; Hong, Wen-Xu; Zhang, Qinghai; Stout, C David; Halpert, James RMolecular pharmacology2010 Apr529-3820061448
Protein-phospholipid interactions in blood clotting.Morrissey, James H; Davis-Harrison, Rebecca L; Tavoosi, Narjes; Ke, Ke; Pureza, Vincent; Boettcher, John M; Clay, Mary C; Rienstra, Chad M; Ohkubo, Y Zenmei; Pogorelov, Taras V; Tajkhorshid, EmadThrombosis research2010 AprS23-520129649
Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.Hiller, Sebastian; Malia, Thomas J; Garces, Robert G; Orekhov, Vladislav Y; Wagner, GerhardBiomolecular NMR assignments2010 Apr29-3220437141
The structure of p85ni in class IA phosphoinositide 3-kinase exhibits interdomain disorder.Sen, K Ilker; Wu, Haiyan; Backer, Jonathan M; Gerfen, Gary JBiochemistry2010 Mar 162159-6620131869
Helix dynamics in LacY: helices II and IV.Liu, Zhenyu; Madej, M Gregor; Kaback, H RonaldJournal of molecular biology2010 Feb 26617-2620043916
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Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.Annalora, Andrew J; Goodin, David B; Hong, Wen-Xu; Zhang, Qinghai; Johnson, Eric F; Stout, C DavidJournal of molecular biology2010 Feb 19441-5119961857
Crystallographic characterization of N-oxide tripod amphiphiles.Chae, Pil Seok; Guzei, Ilia A; Gellman, Samuel HJournal of the American Chemical Society2010 Feb 171953-920095541
Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter.Gros, Yael; Schuldiner, ShimonThe Journal of biological chemistry2010 Feb 125076-8420007701
Presentation of membrane-anchored glycosphingolipids determined from molecular dynamics simulations and NMR paramagnetic relaxation rate enhancement.Demarco, Mari L; Woods, Robert J; Prestegard, James H; Tian, FangJournal of the American Chemical Society2010 Feb 31334-820058858
(1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins.Wu, Chin H; Das, Bibhuti B; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2010 Feb127-3419896874
High resolution NMR spectroscopy of nanocrystalline proteins at ultra-high magnetic field.Sperling, Lindsay J; Nieuwkoop, Andrew J; Lipton, Andrew S; Berthold, Deborah A; Rienstra, Chad MJournal of biomolecular NMR2010 Feb149-5519953303
Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.Zhang, Xi; Chien, Ellen Y T; Chalmers, Michael J; Pascal, Bruce D; Gatchalian, Jovylyn; Stevens, Raymond C; Griffin, Patrick RAnalytical chemistry2010 Feb 11100-820058880
Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases.Kissick, David J; Gualtieri, Ellen J; Simpson, Garth J; Cherezov, VadimAnalytical chemistry2010 Jan 15491-720025250
User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments.Li, Liang; Du, Wenbin; Ismagilov, RustemJournal of the American Chemical Society2010 Jan 13106-1120000708
Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods.Li, Liang; Du, Wenbin; Ismagilov, Rustem FJournal of the American Chemical Society2010 Jan 13112-920000709
An Escherichia coli-based cell-free system for large-scale production of functional mammalian membrane proteins suitable for X-ray crystallography.Nguyen, Tuan A; Lieu, Samantha S; Chang, GeoffreyJournal of molecular microbiology and biotechnology201085-9120160448
Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip.Li, Liang; Ismagilov, Rustem FAnnual review of biophysics2010139-5820192773
Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets.Cherezov, Vadim; Abola, Enrique; Stevens, Raymond CMethods in molecular biology (Clifton, N.J.)2010141-6820665265
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Helical crystallization of soluble and membrane binding proteins.Wilson-Kubalek, Elizabeth M; Chappie, Joshua S; Arthur, Christopher PMethods in enzymology201045-6220887852
Helical crystallization of two example membrane proteins MsbA and the Ca(2+)-ATPase.Glaves, John Paul; Fisher, Lauren; Ward, Andrew; Young, Howard SMethods in enzymology2010143-5920888473
Overexpression and purification of integral membrane proteins in yeast.Hays, Franklin A; Roe-Zurz, Zygy; Stroud, Robert MMethods in enzymology2010695-70720946832
Crystallizing membrane proteins for structure determination using lipidic mesophases.Caffrey, Martin; Porter, ChristopherJournal of visualized experiments : JoVE201021113125
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Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica.Nelson, Patricia A; Khodadoust, Mojgan; Prodhomme, Thomas; Spencer, Collin; Patarroyo, Juan Carlos; Varrin-Doyer, Michel; Ho, Joseph D; Stroud, Robert M; Zamvil, Scott SPloS one2010e1505021151500
Tripod Amphiphiles for Membrane Protein Manipulation.Chae, Pil Seok; Laible, Philip D; Gellman, Samuel HMolecular bioSystems201089-9423814603
NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment.Stanczak, Pawel; Horst, Reto; Serrano, Pedro; Wuthrich, KurtJournal of the American Chemical Society2009 Dec 3018450-619950959
Probing of the rates of alternating access in LacY with Trp fluorescence.Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2009 Dec 2221561-619959662
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Bolaamphiphile-class surfactants can stabilize and support the function of solubilized integral membrane proteins.Li, Qingxin; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Sanders, Charles RBiochemistry2009 Dec 1511606-819908902
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Backbone and side-chain (1)H, (13)C and (15)N resonance assignments of LEN, a human immunoglobulin kappaIV light-chain variable domain.Mukherjee, Sujoy; Pondaven, Simon P; Hofer, Nicole; Jaroniec, Christopher PBiomolecular NMR assignments2009 Dec255-919768664
Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins.Filipp, Fabian V; Sinha, Neeraj; Jairam, Lena; Bradley, Joel; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2009 Dec121-3019781966
Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants.Wu, Haiyan; Shekar, S Chandra; Flinn, Rory J; El-Sibai, Mirvat; Jaiswal, Bijay S; Sen, K Ilker; Janakiraman, Vasantharajan; Seshagiri, Somasekar; Gerfen, Gary J; Girvin, Mark E; Backer, Jonathan MProceedings of the National Academy of Sciences of the United States of America2009 Dec 120258-6319915146
Biomimetic synthesis of lispro insulin via a chemically synthesized "mini-proinsulin" prepared by oxime-forming ligation.Sohma, Youhei; Kent, Stephen B HJournal of the American Chemical Society2009 Nov 1116313-819835355
A Modified Alderman-Grant Coil makes possible an efficient cross-coil probe for high field solid-state NMR of lossy biological samples.Grant, Christopher V; Yang, Yuan; Glibowicka, Mira; Wu, Chin H; Park, Sang Ho; Deber, Charles M; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2009 Nov87-9219733108
Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins.Kim, Hak Jun; Howell, Stanley C; Van Horn, Wade D; Jeon, Young Ho; Sanders, Charles RProgress in nuclear magnetic resonance spectroscopy2009 Nov 1335-36020161395
Structural imperatives impose diverse evolutionary constraints on helical membrane proteins.Oberai, Amit; Joh, Nathan H; Pettit, Frank K; Bowie, James UProceedings of the National Academy of Sciences of the United States of America2009 Oct 2017747-5019815527
Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps.Park, Sang Ho; Son, Woo Sung; Mukhopadhyay, Rishi; Valafar, Homayoun; Opella, Stanley JJournal of the American Chemical Society2009 Oct 1414140-119761238
Protein unfolding with a steric trap.Blois, Tracy M; Hong, Heedeok; Kim, Tae H; Bowie, James UJournal of the American Chemical Society2009 Oct 713914-519739627
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.Cherezov, Vadim; Hanson, Michael A; Griffith, Mark T; Hilgart, Mark C; Sanishvili, Ruslan; Nagarajan, Venugopalan; Stepanov, Sergey; Fischetti, Robert F; Kuhn, Peter; Stevens, Raymond CJournal of the Royal Society, Interface / the Royal Society2009 Oct 6S587-9719535414
Properties of a LacY efflux mutant.Guan, Lan; Kaback, H RonaldBiochemistry2009 Oct 69250-519719233
Effects of impurities on membrane-protein crystallization in different systems.Kors, Christopher A; Wallace, Ellen; Davies, Douglas R; Li, Liang; Laible, Philip D; Nollert, PeterActa crystallographica. Section D, Biological crystallography2009 Oct1062-7319770503
Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB.Tanabe, Mikio; Iverson, Tina MActa crystallographica. Section F, Structural biology and crystallization communications2009 Oct 1996-100019851005
Residues in the H+ translocation site define the pKa for sugar binding to LacY.Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Choe, Jun-Yong; Kaback, H RonaldBiochemistry2009 Sep 228852-6019689129
Coupled decomposition of four-dimensional NOESY spectra.Hiller, Sebastian; Ibraghimov, Ilghis; Wagner, Gerhard; Orekhov, Vladislav YJournal of the American Chemical Society2009 Sep 1612970-819737017
Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center.Ponomarenko, Nina S; Li, Liang; Marino, Antony R; Tereshko, Valentina; Ostafin, Agnes; Popova, Julia A; Bylina, Edward J; Ismagilov, Rustem F; Norris Jr, James RBiochimica et biophysica acta2009 Sep1822-3119539602
A strip-shield improves the efficiency of a solenoid coil in probes for high-field solid-state NMR of lossy biological samples.Wu, Chin H; Grant, Christopher V; Cook, Gabriel A; Park, Sang Ho; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2009 Sep74-8019559634
SlipChip.Du, Wenbin; Li, Liang; Nichols, Kevin P; Ismagilov, Rustem FLab on a chip2009 Aug 212286-9219636458
Similar energetic contributions of packing in the core of membrane and water-soluble proteins.Joh, Nathan H; Oberai, Amit; Yang, Duan; Whitelegge, Julian P; Bowie, James UJournal of the American Chemical Society2009 Aug 1210846-719603754
The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins.Hiller, Sebastian; Wagner, GerhardCurrent opinion in structural biology2009 Aug396-40119665886
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.Katritch, Vsevolod; Reynolds, Kimberly A; Cherezov, Vadim; Hanson, Michael A; Roth, Christopher B; Yeager, Mark; Abagyan, RubenJournal of molecular recognition : JMR2009 Jul-Aug307-1819353579
Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.Himanen, Juha P; Goldgur, Yehuda; Miao, Hui; Myshkin, Eugene; Guo, Hong; Buck, Matthias; Nguyen, My; Rajashankar, Kanagalaghatta R; Wang, Bingcheng; Nikolov, Dimitar BEMBO reports2009 Jul722-819525919
G-protein-coupled receptor structures were not built in a day.Blois, Tracy M; Bowie, James UProtein science : a publication of the Protein Society2009 Jul1335-4219536805
Protein-membrane interactions: blood clotting on nanoscale bilayers.Morrissey, J H; Pureza, V; Davis-Harrison, R L; Sligar, S G; Rienstra, C M; Kijac, A Z; Ohkubo, Y Z; Tajkhorshid, EJournal of thrombosis and haemostasis : JTH2009 Jul169-7219630793
Microfluidic Generation of Lipidic Mesophases for Membrane Protein Crystallization.Perry, Sarah L; Roberts, Griffin W; Tice, Joshua D; Gennis, Robert B; Kenis, Paul J ACrystal growth & design2009 Jun 32566-256920161169
Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes.Diller, Anna; Loudet, Cecile; Aussenac, Fabien; Raffard, Gerard; Fournier, Sylvie; Laguerre, Michel; Grelard, Axelle; Opella, Stanley J; Marassi, Francesca M; Dufourc, Erick JBiochimie2009 Jun744-5119248817
Efficient and accurate estimation of relative order tensors from lambda-maps.Mukhopadhyay, Rishi; Miao, Xijiang; Shealy, Paul; Valafar, HomayounJournal of magnetic resonance (San Diego, Calif. : 1997)2009 Jun236-4719345125
Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Law, Christopher J; Reith, Maarten E A; Wang, Da-NengNature structural & molecular biology2009 Jun652-719430461
The T-lock: automated compensation of radio-frequency induced sample heating.Hiller, Sebastian; Arthanari, Haribabu; Wagner, GerhardJournal of biomolecular NMR2009 Jun69-7619434373
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.Michino, Mayako; Abola, Enrique; GPCR Dock 2008 participants; Brooks 3rd, Charles L; Dixon, J Scott; Moult, John; Stevens, Raymond CNature reviews. Drug discovery2009 Jun455-6319461661
Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods.Mandal, Kalyaneswar; Pentelute, Brad L; Tereshko, Valentina; Thammavongsa, Vilasak; Schneewind, Olaf; Kossiakoff, Anthony A; Kent, Stephen B HProtein science : a publication of the Protein Society2009 Jun1146-5419472324
Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.Ho, Joseph D; Yeh, Ronald; Sandstrom, Andrew; Chorny, Ilya; Harries, William E C; Robbins, Rebecca A; Miercke, Larry J W; Stroud, Robert MProceedings of the National Academy of Sciences of the United States of America2009 May 57437-4219383790
Electrophysiological characterization of LacY.Garcia-Celma, Juan J; Smirnova, Irina N; Kaback, H Ronald; Fendler, KlausProceedings of the National Academy of Sciences of the United States of America2009 May 57373-819383792
Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria.Acehan, Devrim; Khuchua, Zaza; Houtkooper, Riekelt H; Malhotra, Ashim; Kaufman, Johanna; Vaz, Frederic M; Ren, Mindong; Rockman, Howard A; Stokes, David L; Schlame, MichaelMitochondrion2009 Apr86-9519114128
Postnatal expression of V2 vasopressin receptor splice variants in the rat cerebellum.Vargas, Karina J; Sarmiento, Jose M; Ehrenfeld, Pamela; Anazco, Carolina C; Villanueva, Carolina I; Carmona, Pamela L; Brenet, Marianne; Navarro, Javier; Muller-Esterl, Werner; Gonzalez, Carlos BDifferentiation; research in biological diversity2009 Apr377-8519281786
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.Aller, Stephen G; Yu, Jodie; Ward, Andrew; Weng, Yue; Chittaboina, Srinivas; Zhuo, Rupeng; Harrell, Patina M; Trinh, Yenphuong T; Zhang, Qinghai; Urbatsch, Ina L; Chang, GeoffreyScience (New York, N.Y.)2009 Mar 271718-2219325113
An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG).Suarez, Javier; Ranguelova, Kalina; Jarzecki, Andrzej A; Manzerova, Julia; Krymov, Vladimir; Zhao, Xiangbo; Yu, Shengwei; Metlitsky, Leonid; Gerfen, Gary J; Magliozzo, Richard SThe Journal of biological chemistry2009 Mar 137017-2919139099
Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination.Hays, Franklin A; Roe-Zurz, Zygy; Li, Min; Kelly, Libusha; Gruswitz, Franz; Sali, Andrej; Stroud, Robert MJournal of structural and functional genomics2009 Mar9-1619031011
Adenovirus mediated expression "in vivo" of the chemokine receptor CXCR1.Sarmiento, J; Kypreos, K E; Prado, G N; Suetomi, K; Stanzel, C; Maxwell, C; Shumate, D; Tandang-Silvas, M R; Rajarathnam, K; Navarro, JJournal of structural and functional genomics2009 Mar17-2319052917
Nucleotide dependent packing differences in helical crystals of the ABC transporter MsbA.Ward, Andrew; Mulligan, Sheila; Carragher, Bridget; Chang, Geoffrey; Milligan, Ronald AJournal of structural biology2009 Mar169-7519114108
Characterization of the peroxidase mechanism upon reaction of prostacyclin synthase with peracetic acid. Identification of a tyrosyl radical intermediate.Yeh, Hui-Chun; Gerfen, Gary J; Wang, Jinn-Shyan; Tsai, Ah-Lim; Wang, Lee-HoBiochemistry2009 Feb 10917-2819187034
X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.Mandal, Kalyaneswar; Pentelute, Brad L; Tereshko, Valentina; Kossiakoff, Anthony A; Kent, Stephen B HJournal of the American Chemical Society2009 Feb 41362-319133782
Clogging the periplasmic pathway in LacY.Nie, Yiling; Zhou, Yonggang; Kaback, H RonaldBiochemistry2009 Feb 3738-4319128028
Genetic selection system for improving recombinant membrane protein expression in E. coli.Massey-Gendel, Elizabeth; Zhao, Anni; Boulting, Gabriella; Kim, Hye-Yeon; Balamotis, Michael A; Seligman, Len M; Nakamoto, Robert K; Bowie, James UProtein science : a publication of the Protein Society2009 Feb372-8319165721
Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.Goldgur, Yehuda; Paavilainen, Sari; Nikolov, Dimitar; Himanen, J PActa crystallographica. Section F, Structural biology and crystallization communications2009 Feb 171-419193989
Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening.Li, Min; Hays, Franklin A; Roe-Zurz, Zygy; Vuong, Linda; Kelly, Libusha; Ho, Chi-Min; Robbins, Renee M; Pieper, Ursula; O'Connell 3rd, Joseph D; Miercke, Larry J W; Giacomini, Kathleen M; Sali, Andrej; Stroud, Robert MJournal of molecular biology2009 Jan 23820-3019061901
Discovery of new GPCR biology: one receptor structure at a time.Hanson, Michael A; Stevens, Raymond CStructure (London, England : 1993)2009 Jan 148-1419141277
High-throughput biotinylation of proteins.Kay, Brian K; Thai, Sang; Volgina, Veronica VMethods in molecular biology (Clifton, N.J.)2009185-9618988027
Crystallizing membrane proteins for structure determination: use of lipidic mesophases.Caffrey, MartinAnnual review of biophysics200929-5119086821
Proton-detected solid-state NMR spectroscopy of natural-abundance peptide and protein pharmaceuticals.Zhou, Donghua H; Shah, Gautam; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad MAngewandte Chemie (International ed. in English)20091253-619130513
Backbone structure of a small helical integral membrane protein: A unique structural characterization.Page, Richard C; Lee, Sangwon; Moore, Jacob D; Opella, Stanley J; Cross, Timothy AProtein science : a publication of the Protein Society2009 Jan134-4619177358
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A general protocol for the crystallization of membrane proteins for X-ray structural investigation.Newby, Zachary E R; O'Connell 3rd, Joseph D; Gruswitz, Franz; Hays, Franklin A; Harries, William E C; Harwood, Ian M; Ho, Joseph D; Lee, John K; Savage, David F; Miercke, Larry J W; Stroud, Robert MNature protocols2009619-3719360018
Crystallizing membrane proteins using lipidic mesophases.Caffrey, Martin; Cherezov, VadimNature protocols2009706-3119390528
Structural insights into G-protein-coupled receptor activation.Weis, William I; Kobilka, Brian KCurrent opinion in structural biology2008 Dec734-4018957321
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.Jaakola, Veli-Pekka; Griffith, Mark T; Hanson, Michael A; Cherezov, Vadim; Chien, Ellen Y T; Lane, J Robert; Ijzerman, Adriaan P; Stevens, Raymond CScience (New York, N.Y.)2008 Nov 211211-718832607
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase.Slaymaker, Ian M; Bracey, Michael; Mileni, Mauro; Garfunkle, Joie; Cravatt, Benjamin F; Boger, Dale L; Stevens, Raymond CBioorganic & medicinal chemistry letters2008 Nov 155847-5018644727
Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device.Li, Liang; Nachtergaele, Sigrid; Seddon, Annela M; Tereshko, Valentina; Ponomarenko, Nina; Ismagilov, Rustem FJournal of the American Chemical Society2008 Oct 2914324-818831551
Estimation of relative order tensors, and reconstruction of vectors in space using unassigned RDC data and its application.Miao, Xijiang; Mukhopadhyay, Rishi; Valafar, HomayounJournal of magnetic resonance (San Diego, Calif. : 1997)2008 Oct202-1118692422
Orientation and structure of the Ndc80 complex on the microtubule lattice.Wilson-Kubalek, Elizabeth M; Cheeseman, Iain M; Yoshioka, Craig; Desai, Arshad; Milligan, Ronald AThe Journal of cell biology2008 Sep 221055-6118794333
Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus.Cherezov, Vadim; Hofer, Nicole; Szebenyi, Doletha M E; Kolaj, Olga; Wall, J Gerard; Gillilan, Richard; Srinivasan, Vasundara; Jaroniec, Christopher P; Caffrey, MartinStructure (London, England : 1993)2008 Sep 101378-8818786400
Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.Lee, John K; Belogrudov, Grigory I; Stroud, Robert MProceedings of the National Academy of Sciences of the United States of America2008 Sep 913379-8418768789
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.Hiller, Sebastian; Garces, Robert G; Malia, Thomas J; Orekhov, Vladislav Y; Colombini, Marco; Wagner, GerhardScience (New York, N.Y.)2008 Aug 291206-1018755977
Structural biology. Symmetric transporters for asymmetric transport.Karpowich, Nathan K; Wang, Da-NengScience (New York, N.Y.)2008 Aug 8781-218687947
Mirror image forms of snow flea antifreeze protein prepared by total chemical synthesis have identical antifreeze activities.Pentelute, Brad L; Gates, Zachary P; Dashnau, Jennifer L; Vanderkooi, Jane M; Kent, Stephen B HJournal of the American Chemical Society2008 Jul 309702-718598026
X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers.Pentelute, Brad L; Gates, Zachary P; Tereshko, Valentina; Dashnau, Jennifer L; Vanderkooi, Jane M; Kossiakoff, Anthony A; Kent, Stephen B HJournal of the American Chemical Society2008 Jul 309695-70118598029
Glycotripod amphiphiles for solubilization and stabilization of a membrane-protein superassembly: importance of branching in the hydrophilic portion.Chae, Pil S; Wander, Marc J; Bowling, Aaron P; Laible, Philip D; Gellman, Samuel HChembiochem : a European journal of chemical biology2008 Jul 211706-918576450
Solid-state NMR spectroscopy of a membrane protein in biphenyl phospholipid bicelles with the bilayer normal parallel to the magnetic field.Park, Sang Ho; Loudet, Cecile; Marassi, Francesca M; Dufourc, Erick J; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2008 Jul133-818492613
Protonation and sugar binding to LacY.Smirnova, Irina N; Kasho, Vladimir; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2008 Jul 18896-90118567672
Orientation of the Escherichia coli outer membrane protein OmpX in phospholipid bilayer membranes determined by solid-State NMR.Mahalakshmi, Radhakrishnan; Marassi, Francesca MBiochemistry2008 Jun 246531-818512961
The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway.Nie, Yiling; Sabetfard, Frances E; Kaback, H RonaldJournal of molecular biology2008 Jun 13695-70318485365
Microscale NMR screening of new detergents for membrane protein structural biology.Zhang, Qinghai; Horst, Reto; Geralt, Michael; Ma, Xingquan; Hong, Wen-Xu; Finn, M G; Stevens, Raymond C; Wuthrich, KurtJournal of the American Chemical Society2008 Jun 117357-6318479092
Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum.Newby, Zachary E R; O'Connell 3rd, Joseph; Robles-Colmenares, Yaneth; Khademi, Shahram; Miercke, Larry J; Stroud, Robert MNature structural & molecular biology2008 Jun619-2518500352
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.Hanson, Michael A; Cherezov, Vadim; Griffith, Mark T; Roth, Christopher B; Jaakola, Veli-Pekka; Chien, Ellen Y T; Velasquez, Jeffrey; Kuhn, Peter; Stevens, Raymond CStructure (London, England : 1993)2008 Jun897-90518547522
High-performance solvent suppression for proton detected solid-state NMR.Zhou, Donghua H; Rienstra, Chad MJournal of magnetic resonance (San Diego, Calif. : 1997)2008 May167-7218276175
Rapid classification of protein structure models using unassigned backbone RDCs and probability density profile analysis (PDPA).Bansal, Sonal; Miao, Xijiang; Adams, Michael W W; Prestegard, James H; Valafar, HomayounJournal of magnetic resonance (San Diego, Calif. : 1997)2008 May60-818321742
Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments.Asmar-Rovira, Guillermo A; Asseo-Garcia, Aloysha M; Quesada, Orestes; Hanson, Michael A; Cheng, Anchi; Nogueras, Carlos; Lasalde-Dominicci, Jose A; Stevens, Raymond CThe Journal of membrane biology2008 May13-2618581036
In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.Cherezov, Vadim; Liu, Wei; Derrick, Jeremy P; Luan, Binquan; Aksimentiev, Aleksei; Katritch, Vsevolod; Caffrey, MartinProteins2008 Apr24-3418076035
REDCRAFT: a tool for simultaneous characterization of protein backbone structure and motion from RDC data.Bryson, Michael; Tian, Fang; Prestegard, James H; Valafar, HomayounJournal of magnetic resonance (San Diego, Calif. : 1997)2008 Apr322-3418258464
Expression and function of the rat vesicular monoamine transporter 2.Adam, Yoav; Edwards, Robert H; Schuldiner, ShimonAmerican journal of physiology. Cell physiology2008 AprC1004-1118287335
Opening and closing of the periplasmic gate in lactose permease.Zhou, Yonggang; Guan, Lan; Freites, J Alfredo; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2008 Mar 113774-818319336
Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure.Roth, Christopher B; Hanson, Michael A; Stevens, Raymond CJournal of molecular biology2008 Mar 71305-1918222471
Microscale fluorescent thermal stability assay for membrane proteins.Alexandrov, Alexander I; Mileni, Mauro; Chien, Ellen Y T; Hanson, Michael A; Stevens, Raymond CStructure (London, England : 1993)2008 Mar351-918334210
Shiftless nuclear magnetic resonance spectroscopy.Wu, Chin H; Opella, Stanley JThe Journal of chemical physics2008 Feb 705231218266429
New G-protein-coupled receptor crystal structures: insights and limitations.Kobilka, Brian; Schertler, Gebhard F XTrends in pharmacological sciences2008 Feb79-8318194818
In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels.Ng, Joseph D; Clark, Peter J; Stevens, Raymond C; Kuhn, PeterActa crystallographica. Section D, Biological crystallography2008 Feb189-9718219119
Chemical shift assignment of the transmembrane helices of DsbB, a 20-kDa integral membrane enzyme, by 3D magic-angle spinning NMR spectroscopy.Li, Ying; Berthold, Deborah A; Gennis, Robert B; Rienstra, Chad MProtein science : a publication of the Protein Society2008 Feb199-20418227427
Proton-detected separated local field spectroscopy.Wu, Chin H; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2008 Jan165-7017981481
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae.Drew, David; Newstead, Simon; Sonoda, Yo; Kim, Hyun; von Heijne, Gunnar; Iwata, SoNature protocols2008784-9818451787
Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics.Ng, Joseph D; Stevens, Raymond C; Kuhn, PeterMethods in molecular biology (Clifton, N.J.)2008363-7618542876
Rapid analysis of organic compounds by proton-detected heteronuclear correlation NMR spectroscopy with 40 kHz magic-angle spinning.Zhou, Donghua H; Rienstra, Chad MAngewandte Chemie (International ed. in English)20087328-3118683840
HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures.Ho, Bosco K; Gruswitz, FranzBMC structural biology20084919014592
LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization.Cherezov, Vadim; Liu, Jeffrey; Griffith, Mark; Hanson, Michael A; Stevens, Raymond CCrystal growth & design20084307-431519234616
Crystal polymorphism of protein GB1 examined by solid-state NMR spectroscopy and X-ray diffraction.Schmidt, Heather L Frericks; Sperling, Lindsay J; Gao, Yi Gui; Wylie, Benjamin J; Boettcher, John M; Wilson, Scott R; Rienstra, Chad MThe journal of physical chemistry. B2007 Dec 2714362-918052145
NMR structural studies of the bacterial outer membrane protein OmpX in oriented lipid bilayer membranes.Mahalakshmi, Radhakrishnan; Franzin, Carla M; Choi, Jungyuen; Marassi, Francesca MBiochimica et biophysica acta2007 Dec3216-2417916325
A high-throughput strategy to screen 2D crystallization trials of membrane proteins.Vink, Martin; Derr, Kd; Love, James; Stokes, David L; Ubarretxena-Belandia, IbanJournal of structural biology2007 Dec295-30417951070
NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization.Lee, Sangwon; Howell, Stephen B; Opella, Stanley JBiochimica et biophysica acta2007 Dec3127-3417959139
High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy.Rupasinghe, Sanjeewa G; Duan, Hui; Frericks Schmidt, Heather L; Berthold, Deborah A; Rienstra, Chad M; Schuler, Mary ABiochimica et biophysica acta2007 Dec3061-7018005930
Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins.Sinha, Neeraj; Filipp, Fabian V; Jairam, Lena; Park, Sang Ho; Bradley, Joel; Opella, Stanley JMagnetic resonance in chemistry : MRC2007 DecS107-1518157808
Flexibility in the ABC transporter MsbA: Alternating access with a twist.Ward, Andrew; Reyes, Christopher L; Yu, Jodie; Roth, Christopher B; Chang, GeoffreyProceedings of the National Academy of Sciences of the United States of America2007 Nov 2719005-1018024585
X-ray structure of EmrE supports dual topology model.Chen, Yen-Ju; Pornillos, Owen; Lieu, Samantha; Ma, Che; Chen, Andy P; Chang, GeoffreyProceedings of the National Academy of Sciences of the United States of America2007 Nov 2718999-900418024586
Site-directed alkylation of LacY: effect of the proton electrochemical gradient.Nie, Yiling; Ermolova, Natalia; Kaback, H RonaldJournal of molecular biology2007 Nov 23356-6417920075
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.Rosenbaum, Daniel M; Cherezov, Vadim; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Yao, Xiao-Jie; Weis, William I; Stevens, Raymond C; Kobilka, Brian KScience (New York, N.Y.)2007 Nov 231266-7317962519
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.Cherezov, Vadim; Rosenbaum, Daniel M; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Kuhn, Peter; Weis, William I; Kobilka, Brian K; Stevens, Raymond CScience (New York, N.Y.)2007 Nov 231258-6517962520
TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.Menuz, Karen; Stroud, Robert M; Nicoll, Roger A; Hays, Franklin AScience (New York, N.Y.)2007 Nov 2815-717975069
Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression.Hanson, Michael A; Brooun, Alexei; Baker, Kent A; Jaakola, Veli-Pekka; Roth, Chris; Chien, Ellen Y T; Alexandrov, Alexander; Velasquez, Jeffrey; Davis, Leila; Griffith, Mark; Moy, Kin; Ganser-Pornillos, Barbie K; Hua, Yuanzi; Kuhn, Peter; Ellis, Sam; YeagProtein expression and purification2007 Nov85-9217723307
High resolution 1H NMR of a lipid cubic phase using a solution NMR probe.Boyle-Roden, E; Hoefer, N; Dey, K K; Grandinetti, P J; Caffrey, MJournal of magnetic resonance (San Diego, Calif. : 1997)2007 Nov13-917855136
Structure refinement of the OpcA adhesin using molecular dynamics.Luan, Binquan; Caffrey, Martin; Aksimentiev, AlekseiBiophysical journal2007 Nov 13058-6917938421
Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction.Plotkowski, Megan L; Kim, Sanguk; Phillips, Martin L; Partridge, Anthony W; Deber, Charles M; Bowie, James UBiochemistry2007 Oct 3012164-7317915947
Sugar binding induces an outward facing conformation of LacY.Smirnova, Irina; Kasho, Vladimir; Choe, Jun-Yong; Altenbach, Christian; Hubbell, Wayne L; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2007 Oct 1616504-917925435
An efficient (1)H/(31)P double-resonance solid-state NMR probe that utilizes a scroll coil.Grant, Christopher V; Sit, Siu-Ling; De Angelis, Anna A; Khuong, Kelli S; Wu, Chin H; Plesniak, Leigh A; Opella, Stanley JJournal of magnetic resonance (San Diego, Calif. : 1997)2007 Oct279-8417719813
Cell-cell signaling via Eph receptors and ephrins.Himanen, Juha-Pekka; Saha, Nayanendu; Nikolov, Dimitar BCurrent opinion in cell biology2007 Oct534-4217928214
Proton-detected solid-state NMR spectroscopy of fully protonated proteins at 40 kHz magic-angle spinning.Zhou, Donghua H; Shah, Gautam; Cormos, Mircea; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad MJournal of the American Chemical Society2007 Sep 2611791-80117725352
Structural determination of wild-type lactose permease.Guan, Lan; Mirza, Osman; Verner, Gillian; Iwata, So; Kaback, H RonaldProceedings of the National Academy of Sciences of the United States of America2007 Sep 2515294-817881559
Modular total chemical synthesis of a human immunodeficiency virus type 1 protease.Johnson, Erik C B; Malito, Enrico; Shen, Yuequan; Rich, Dan; Tang, Wei-Jen; Kent, Stephen B HJournal of the American Chemical Society2007 Sep 1911480-9017705484
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Goetz, Regina M; Law, Christopher J; Reith, Maarten E A; Wang, Da-NengScience (New York, N.Y.)2007 Sep 71390-317690258
Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit.Rajagopal, Sudarshan; Kent, Stephen B HProtein science : a publication of the Protein Society2007 Sep2056-6417660260
Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus.Hofer, Nicole; Kolaj, Olga; Li, Hui; Cherezov, Vadim; Gillilan, Richard; Wall, J Gerard; Caffrey, MartinActa crystallographica. Section F, Structural biology and crystallization communications2007 Aug 1673-717671365
When biochemistry meets structural biology: the cautionary tale of EmrE.Schuldiner, ShimonTrends in biochemical sciences2007 Jun252-817452106
Crystal structure of the human ephrin-A5 ectodomain.Nikolov, Dimitar; Li, Chen; Lackmann, Martin; Jeffrey, Philip; Himanen, JuhaProtein science : a publication of the Protein Society2007 May996-100017400922
Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: comparing theory and experiments.Li, Liang; Boedicker, James Q; Ismagilov, Rustem FAnalytical chemistry2007 Apr 12756-6117338503
Partial (13)C and (15)N chemical-shift assignments of the disulfide-bond-forming enzyme DsbB by 3D magic-angle spinning NMR spectroscopy.Li, Ying; Berthold, Deborah A; Frericks, Heather L; Gennis, Robert B; Rienstra, Chad MChembiochem : a European journal of chemical biology2007 Mar 5434-4217285659
Towards the total chemical synthesis of integral membrane proteins: a general method for the synthesis of hydrophobic peptide-thioester building blocks.Johnson, Erik C B; Kent, Stephen B HTetrahedron letters2007 Mar 51795-179919177172
Kinetic analysis of the binding of monomeric and dimeric ephrins to Eph receptors: correlation to function in a growth cone collapse assay.Pabbisetty, Kumar B; Yue, Xin; Li, Chen; Himanen, Juha-Pekka; Zhou, Renping; Nikolov, Dimitar B; Hu, LongqinProtein science : a publication of the Protein Society2007 Mar355-6117322526
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.Malia, Thomas J; Wagner, GerhardBiochemistry2007 Jan 16514-2517209561
Exploratory synthesis of peptide-alpha-thioester segments spanning the polypeptide sequence of the delta-opioid receptor, a G protein-coupled receptor.Johnson, Erik C B; Kent, Stephen B HBiopolymers2007340-917120238
Designing facial amphiphiles for the stabilization of integral membrane proteins.Zhang, Qinghai; Ma, Xingquan; Ward, Andrew; Hong, Wen-Xu; Jaakola, Veli-Pekka; Stevens, Raymond C; Finn, M G; Chang, GeoffreyAngewandte Chemie (International ed. in English)20077023-517691085
Solid-state protein-structure determination with proton-detected triple-resonance 3D magic-angle-spinning NMR spectroscopy.Zhou, Donghua H; Shea, John J; Nieuwkoop, Andrew J; Franks, W Trent; Wylie, Benjamin J; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad MAngewandte Chemie (International ed. in English)20078380-317907259
Bicelle samples for solid-state NMR of membrane proteins.De Angelis, Anna A; Opella, Stanley JNature protocols20072332-817947974
Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction.Cherezov, Vadim; Caffrey, MartinFaraday discussions2007195-212; discussion 213-2917955811
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.Li, Liang; Mustafi, Debarshi; Fu, Qiang; Tereshko, Valentina; Chen, Delai L; Tice, Joshua D; Ismagilov, Rustem FProceedings of the National Academy of Sciences of the United States of America2006 Dec 1919243-817159147
In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution.Cherezov, V; Yamashita, E; Liu, W; Zhalnina, M; Cramer, W A; Caffrey, MJournal of molecular biology2006 Dec 8716-3417028020
Reactions in droplets in microfluidic channels.Song, Helen; Chen, Delai L; Ismagilov, Rustem FAngewandte Chemie (International ed. in English)2006 Nov 137336-5617086584
Controlling the passage of light through metal microchannels by nanocoatings of phospholipids.Teeters-Kennedy, Shannon M; Rodriguez, Kenneth R; Rogers, Trisha M; Zomchek, Keith A; Williams, Shaun M; Sudnitsyn, Alexandra; Carter, Lauren; Cherezov, Vadim; Caffrey, Martin; Coe, James VThe journal of physical chemistry. B2006 Nov 221719-2717064131
Ultrafast hydration dynamics in the lipidic cubic phase: Discrete water structures in nanochannels.Kim, Jongjoo; Lu, Wenyun; Qiu, Weihong; Wang, Lijuan; Caffrey, Martin; Zhong, DongpingThe journal of physical chemistry. B2006 Nov 221994-200017064169
Interactions of tryptophan, tryptophan peptides, and tryptophan alkyl esters at curved membrane interfaces.Liu, Wei; Caffrey, MartinBiochemistry2006 Oct 311713-2617002272
Structure determination of a membrane protein with two trans-membrane helices in aligned phospholipid bicelles by solid-state NMR spectroscopy.De Angelis, Anna A; Howell, Stanley C; Nevzorov, Alexander A; Opella, Stanley JJournal of the American Chemical Society2006 Sep 2012256-6716967977
Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices.Adamson, David N; Mustafi, Debarshi; Zhang, John X J; Zheng, Bo; Ismagilov, Rustem FLab on a chip2006 Sep1178-8616929397
Magic-angle spinning solid-state NMR of a 144 kDa membrane protein complex: E. coli cytochrome bo3 oxidase.Frericks, Heather L; Zhou, Donghua H; Yap, Lai Lai; Gennis, Robert B; Rienstra, Chad MJournal of biomolecular NMR2006 Sep55-7116964530
Identification of individual protein-ligand NOEs in the limit of intermediate exchange.Reibarkh, Mikhail; Malia, Thomas J; Hopkins, Brian T; Wagner, GerhardJournal of biomolecular NMR2006 Sep1-1116964534
High-resolution NMR spectroscopy of a GPCR in aligned bicelles.Park, Sang Ho; Prytulla, Stefan; De Angelis, Anna A; Brown, Jonathan Miles; Kiefer, Hans; Opella, Stanley JJournal of the American Chemical Society2006 Jun 147402-316756269
Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening.Chen, Delai L; Ismagilov, Rustem FCurrent opinion in chemical biology2006 Jun226-3116677848
Room to move: crystallizing membrane proteins in swollen lipidic mesophases.Cherezov, Vadim; Clogston, Jeffrey; Papiz, Miroslav Z; Caffrey, MartinJournal of molecular biology.2006 Apr 141605-1816490208
NMR distinction of single- and multiple-mode binding of small-molecule protein ligands.Reibarkh, Mikhail; Malia, Thomas J; Wagner, GerhardJournal of the American Chemical Society2006 Feb 222160-116478139
An architectural framework that may lie at the core of the postsynaptic density.Baron, Marisa K; Boeckers, Tobias M; Vaida, Bianca; Faham, Salem; Gingery, Mari; Sawaya, Michael R; Salyer, Danielle; Gundelfinger, Eckart D; Bowie, James UScience (New York, N.Y.)2006 Jan 27531-516439662
The Membrane Protein Data Bank.Raman, P; Cherezov, V; Caffrey, MCellular and molecular life sciences : CMLS2006 Jan36-5116314922
X-ray structure of the EmrE multidrug transporter in complex with a substrate.Pornillos, Owen; Chen, Yen-Ju; Chen, Andy P; Chang, GeoffreyScience (New York, N.Y.)2005 Dec 231950-316373573
Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters.Vardy, Eyal; Steiner-Mordoch, Sonia; Schuldiner, ShimonJournal of bacteriology. 2005 Nov7518-2516237035
The past, present and future of cell-free protein synthesis.Katzen, Federico; Chang, Geoffrey; Kudlicki, WieslawTrends in biotechnology. 2005 Mar150-615734558
Synthesis of fluorescein labeled 7-methylguanosinemonophosphate.Natarajan, Amarnath; Moerke, Nathan; Fan, Yun-Hua; Chen, Han; Christ, William J; Wagner, Gerhard; Halperin, Jose ABioorganic & medicinal chemistry letters2004 May 172657-6015109672


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