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Regulatory Science (292)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity.Bale, Shyam Sundhar; Sridharan, Gautham Vivek; Golberg, Inna; Prodanov, Ljupcho; McCarty, William J; Usta, Osman Berk; Jindal, Rohit; Yarmush, Martin LTechnology.2015 Dec;155-16226925437
Transdifferentiation of human endothelial progenitors into smooth muscle cells.Ji, HaYeun; Atchison, Leigh; Chen, Zaozao; Chakraborty, Syandan; Jung, Youngmee; Truskey, George A; Christoforou, Nicolas; Leong, Kam WBiomaterials.2016 Apr;180-9426874281
Enterohemorrhagic Escherichia coli reduce mucus and intermicrovillar bridges in human stem cell-derived colonoids.In, Julie; Foulke-Abel, Jennifer; Zachos, Nicholas C; Hansen, Anne-Marie; Kaper, James B; Bernstein, Harris D; Halushka, Marc; Blutt, Sarah; Estes, Mary K; Donowitz, Mark; Kovbasnjuk, OlgaCellular and molecular gastroenterology and hepatology.2016 Jan 1;48-62.e326855967
Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification.Logan, David J; Shan, Jing; Bhatia, Sangeeta N; Carpenter, Anne EMethods (San Diego, Calif.).2016 Mar 1;11-Jun26687239
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology.Foulke-Abel, Jennifer; In, Julie; Yin, Jianyi; Zachos, Nicholas C; Kovbasnjuk, Olga; Estes, Mary K; de Jonge, Hugo; Donowitz, MarkGastroenterology.2016 Mar;638-649.e826677983
Stretchable Hydrogel Electronics and Devices.Lin, Shaoting; Yuk, Hyunwoo; Zhang, Teng; Parada, German Alberto; Koo, Hyunwoo; Yu, Cunjiang; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Dec 7;26639322
Novel behavior of the chromatographic separation of linear and cyclic polymers.Montenegro-Burke, J Rafael; Bennett, Jackson M; McLean, John A; Hercules, David MAnalytical and bioanalytical chemistry.2016 Jan;677-8126637218
Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study.Guetterman, Timothy C; Fetters, Michael D; Legocki, Laurie J; Mawocha, Samkeliso; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William JClinical research and regulatory affairs.2015 Oct 2;121-13026622163
Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1?/nerve growth factor signaling.Jiang, Yangzi; Hu, Changchang; Yu, Shuting; Yan, Junwei; Peng, Hsuan; Ouyang, Hong Wei; Tuan, Rocky SArthritis research & therapy.2015;32726577823
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.Brown, Jacquelyn A; Pensabene, Virginia; Markov, Dmitry A; Allwardt, Vanessa; Neely, M Diana; Shi, Mingjian; Britt, Clayton M; Hoilett, Orlando S; Yang, Qing; Brewer, Bryson M; Samson, Philip C; McCawley, Lisa J; May, James M; Webb, Donna J; Li, Deyu; BowBiomicrofluidics.2015 Sep;5412426576206
Tough bonding of hydrogels to diverse non-porous surfaces.Yuk, Hyunwoo; Zhang, Teng; Lin, Shaoting; Parada, German Alberto; Zhao, XuanheNature materials.2016 Feb;190-626552058
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization.McCarty, William J; Prodanov, Ljupcho; Bale, Shyam Sundhar; Bhushan, Abhinav; Jindal, Rohit; Yarmush, Martin L; Usta, O BerkJournal of visualized experiments : JoVE.2015;26485274
Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia.Kong, Jianping; Sai, Hong; Crissey, Mary Ann S; Jhala, Nirag; Falk, Gary W; Ginsberg, Gregory G; Abrams, Julian A; Nakagawa, Hiroshi; Wang, Kenneth; Rustgi, Anil K; Wang, Timothy C; Lynch, John POncotarget.2015 Oct 20;32980-300526460825
Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels.Jung, Youngmee; Ji, HaYeun; Chen, Zaozao; Fai Chan, Hon; Atchison, Leigh; Klitzman, Bruce; Truskey, George; Leong, Kam WScientific reports.2015;1511626456074
Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors.Thakore, Pratiksha I; Gersbach, Charles AMethods in molecular biology (Clifton, N.J.).2016;71-8826443215
The Development of TALE Nucleases for Biotechnology.Ousterout, David G; Gersbach, Charles AMethods in molecular biology (Clifton, N.J.).2016;27-4226443211
Enabling functional genomics with genome engineering.Hilton, Isaac B; Gersbach, Charles AGenome research.2015 Oct;1442-5526430154
In vitro cardiac tissue models: Current status and future prospects.Mathur, Anurag; Ma, Zhen; Loskill, Peter; Jeeawoody, Shaheen; Healy, Kevin EAdvanced drug delivery reviews.2016 Jan 15;203-1326428618
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin.Pellett, Sabine; Schwartz, Michael P; Tepp, William H; Josephson, Richard; Scherf, Jacob M; Pier, Christina L; Thomson, James A; Murphy, William L; Johnson, Eric AScientific reports.2015;1456626411797
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.Schwartz, Michael P; Hou, Zhonggang; Propson, Nicholas E; Zhang, Jue; Engstrom, Collin J; Santos Costa, Vitor; Jiang, Peng; Nguyen, Bao Kim; Bolin, Jennifer M; Daly, William; Wang, Yu; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James AProceedings of the National Academy of Sciences of the United States of America.2015 Oct 6;12516-2126392547
Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.Kong, Jianping; Whelan, Kelly A; Laczkó, Dorottya; Dang, Brendan; Caro Monroig, Angeliz; Soroush, Ali; Falcone, John; Amaravadi, Ravi K; Rustgi, Anil K; Ginsberg, Gregory G; Falk, Gary W; Nakagawa, Hiroshi; Lynch, John PMolecular carcinogenesis.2015 Sep 16;26373456
Melanin Transfer in Human 3D Skin Equivalents Generated Exclusively from Induced Pluripotent Stem Cells.Gledhill, Karl; Guo, Zongyou; Umegaki-Arao, Noriko; Higgins, Claire A; Itoh, Munenari; Christiano, Angela MPloS one.2015;e013671326308443
Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments.Leng, Ning; Chu, Li-Fang; Barry, Chris; Li, Yuan; Choi, Jeea; Li, Xiaomao; Jiang, Peng; Stewart, Ron M; Thomson, James A; Kendziorski, ChristinaNature methods.2015 Oct;947-5026301841
Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip.Agarwal, Ashutosh; Farouz, Yohan; Nesmith, Alexander Peyton; Deravi, Leila F; McCain, Megan Laura; Parker, Kevin KitAdvanced functional materials.2013 Aug 12;3738-374626213529
A human liver microphysiology platform for investigating physiology, drug safety, and disease models.Vernetti, Lawrence A; Senutovitch, Nina; Boltz, Robert; DeBiasio, Richard; Ying Shun, Tong; Gough, Albert; Taylor, D LansingExperimental biology and medicine (Maywood, N.J.).2016 Jan;101-1426202373
3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Jul 15;403426172844
Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.Usta, O B; McCarty, W J; Bale, S; Hegde, M; Jindal, R; Bhushan, A; Golberg, I; Yarmush, M LTechnology.2015 Mar;26-Jan26167518
Long-term maintenance of a microfluidic 3D human liver sinusoid.Prodanov, Ljupcho; Jindal, Rohit; Bale, Shyam Sundhar; Hegde, Manjunath; McCarty, William J; Golberg, Inna; Bhushan, Abhinav; Yarmush, Martin L; Usta, Osman BerkBiotechnology and bioengineering.2016 Jan;241-626152452
Bioengineering methods for myocardial regeneration.Parsa, Hesam; Ronaldson, Kacey; Vunjak-Novakovic, GordanaAdvanced drug delivery reviews.2015 Jul 4;26150344
Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode.McKenzie, Jennifer R; Cognata, Andrew C; Davis, Anna N; Wikswo, John P; Cliffel, David EAnalytical chemistry.2015 Aug 4;7857-6426125545
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors.Bagley, Alexander F; Scherz-Shouval, Ruth; Galie, Peter A; Zhang, Angela Q; Wyckoff, Jeffrey; Whitesell, Luke; Chen, Christopher S; Lindquist, Susan; Bhatia, Sangeeta NCancer research.2015 Aug 15;3255-6726122846
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.Hong, Sungmin; Sycks, Dalton; Chan, Hon Fai; Lin, Shaoting; Lopez, Gabriel P; Guilak, Farshid; Leong, Kam W; Zhao, XuanheAdvanced materials (Deerfield Beach, Fla.).2015 Jul 15;4035-4026033288
Tissue-engineered blood vessels as promising tools for testing drug toxicity.Truskey, George A; Fernandez, Cristina EExpert opinion on drug metabolism & toxicology.2015 Jul;1021-426028128
MicroRNA delivery for regenerative medicine.Peng, Bo; Chen, Yongming; Leong, Kam WAdvanced drug delivery reviews.2015 Jul 1;108-2226024978
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.Chen, Huanhuan Joyce; Sun, Jian; Huang, Zhiliang; Hou Jr, Harry; Arcilla, Myra; Rakhilin, Nikolai; Joe, Daniel J; Choi, Jiahn; Gadamsetty, Poornima; Milsom, Jeff; Nandakumar, Govind; Longman, Randy; Zhou, Xi Kathy; Edwards, Robert; Chen, Jonlin; Chen, KaiNature biotechnology.2015 Jun;656-6026006007
Fluorescence lifetime imaging of endogenous biomarker of oxidative stress.Datta, Rupsa; Alfonso-García, Alba; Cinco, Rachel; Gratton, EnricoScientific reports.2015;984825993434
Fluorescent protein biosensors applied to microphysiological systems.Senutovitch, Nina; Vernetti, Lawrence; Boltz, Robert; DeBiasio, Richard; Gough, Albert; Taylor, D LansingExperimental biology and medicine (Maywood, N.J.).2015 Jun;795-80825990438
A phenotypic in vitro model for the main determinants of human whole heart function.Stancescu, Maria; Molnar, Peter; McAleer, Christopher W; McLamb, William; Long, Christopher J; Oleaga, Carlota; Prot, Jean-Matthieu; Hickman, James JBiomaterials.2015 Aug;20-3025978005
Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues.Feric, Nicole T; Radisic, MilicaAdvanced drug delivery reviews.2015 May 5;25956564
Clinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis.Legocki, Laurie J; Meurer, William J; Frederiksen, Shirley; Lewis, Roger J; Durkalski, Valerie L; Berry, Donald A; Barsan, William G; Fetters, Michael DBMC medical ethics.2015;2725933921
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor.Sarkar, Ujjal; Rivera-Burgos, Dinelia; Large, Emma M; Hughes, David J; Ravindra, Kodihalli C; Dyer, Rachel L; Ebrahimkhani, Mohammad R; Wishnok, John S; Griffith, Linda G; Tannenbaum, Steven RDrug metabolism and disposition: the biological fate of chemicals.2015 Jul;1091-925926431
Differential ?3 Integrin Expression Regulates the Response of Human Lung and Cardiac Fibroblasts to Extracellular Matrix and Its Components.Merna, Nick; Fung, Kelsey M; Wang, Jean J; King, Cristi R; Hansen, Kirk C; Christman, Karen L; George, Steven CTissue engineering. Part A.2015 Aug;2195-20525926101
NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection.Juul, Sissel; Obliosca, Judy M; Liu, Cong; Liu, Yen-Liang; Chen, Yu-An; Imphean, Darren M; Knudsen, Birgitta R; Ho, Yi-Ping; Leong, Kam W; Yeh, Hsin-ChihNanoscale.2015 May 14;8332-725901841
The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial: an adaptive trial design case study.Connor, Jason T; Broglio, Kristine R; Durkalski, Valerie; Meurer, William J; Johnston, Karen CTrials.2015;7225885963
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow.Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael LLab on a chip.2015 May 21;2269-7725857666
Culturing adult stem cells from mouse small intestinal crypts.Hamilton, Kathryn E; Crissey, Mary Ann S; Lynch, John P; Rustgi, Anil KCold Spring Harbor protocols.2015 Apr;354-825834260
A cost-effective RNA sequencing protocol for large-scale gene expression studies.Hou, Zhonggang; Jiang, Peng; Swanson, Scott A; Elwell, Angela L; Nguyen, Bao Kim S; Bolin, Jennifer M; Stewart, Ron; Thomson, James AScientific reports.2015;957025831155
Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI.Xu, Libin; Kliman, Michal; Forsythe, Jay G; Korade, Zeljka; Hmelo, Anthony B; Porter, Ned A; McLean, John AJournal of the American Society for Mass Spectrometry.2015 Jun;924-3325822928
Generating human intestinal tissues from pluripotent stem cells to study development and disease.Sinagoga, Katie L; Wells, James MThe EMBO journal.2015 May 5;1149-6325792515
Integration of drug, protein, and gene delivery systems with regenerative medicine.Lorden, Elizabeth R; Levinson, Howard M; Leong, Kam WDrug delivery and translational research.2015 Apr;168-8625787742
Engineering the ovarian cycle using in vitro follicle culture.Skory, Robin M; Xu, Yuanming; Shea, Lonnie D; Woodruff, Teresa KHuman reproduction (Oxford, England).2015 Jun;1386-9525784584
Engineering mesenchymal stem cells for regenerative medicine and drug delivery.Park, Ji Sun; Suryaprakash, Smruthi; Lao, Yeh-Hsing; Leong, Kam WMethods (San Diego, Calif.).2015 Aug;16-Mar25770356
Phage-display-guided nanocarrier targeting to atheroprone vasculature.Hofmeister, Lucas H; Lee, Sue Hyun; Norlander, Allison E; Montaniel, Kim Ramil C; Chen, Wei; Harrison, David G; Sung, Hak-JoonACS nano.2015;4435-4625768046
Human iPSC-based cardiac microphysiological system for drug screening applications.Mathur, Anurag; Loskill, Peter; Shao, Kaifeng; Huebsch, Nathaniel; Hong, SoonGweon; Marcus, Sivan G; Marks, Natalie; Mandegar, Mohammad; Conklin, Bruce R; Lee, Luke P; Healy, Kevin EScientific reports.2015;888325748532
Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models.Nakagawa, Hiroshi; Whelan, Kelly; Lynch, John PBest practice & research. Clinical gastroenterology.2015 Feb;16-Mar25743452
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling.Abaci, Hasan Erbil; Shuler, Michael LIntegrative biology : quantitative biosciences from nano to macro.2015 Apr;383-9125739725
Initiation of puberty in mice following decellularized ovary transplant.Laronda, Monica M; Jakus, Adam E; Whelan, Kelly A; Wertheim, Jason A; Shah, Ramille N; Woodruff, Teresa KBiomaterials.2015 May;20-925736492
Vessel network formation in response to intermittent hypoxia is frequency dependent.Ehsan, Seema M; George, Steven CJournal of bioscience and bioengineering.2015 Sep;347-5025735591
Structural phenotyping of stem cell-derived cardiomyocytes.Pasqualini, Francesco Silvio; Sheehy, Sean Paul; Agarwal, Ashutosh; Aratyn-Schaus, Yvonne; Parker, Kevin KitStem cell reports.2015 Mar 10;340-725733020
Real-time cellular exometabolome analysis with a microfluidic-mass spectrometry platform.Marasco, Christina C; Enders, Jeffrey R; Seale, Kevin T; McLean, John A; Wikswo, John PPloS one.2015;e011768525723555
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Majoros, William H; Reddy, Timothy E; Gersbach, Charles ANature communications.2015 Feb 18;624425692716
Use of an organotypic mammalian in vitro follicle growth assay to facilitate female reproductive toxicity screening.Xu, Yuanming; Duncan, Francesca E; Xu, Min; Woodruff, Teresa KReproduction, fertility, and development.2015 Feb 18;25689754
S100B blood levels and childhood trauma in adolescent inpatients.Falcone, Tatiana; Janigro, Damir; Lovell, Rachel; Simon, Barry; Brown, Charles A; Herrera, Mariela; Myint, Aye Mu; Anand, AmitJournal of psychiatric research.2015 Mar;14-2225669696
CXCR3 in carcinoma progression.Ma, Bo; Khazali, Ahmad; Wells, AlanHistology and histopathology.2015 Jul;781-9225663474
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.Ng, Shengyong; Schwartz, Robert E; March, Sandra; Galstian, Ani; Gural, Nil; Shan, Jing; Prabhu, Mythili; Mota, Maria M; Bhatia, Sangeeta NStem cell reports.2015 Mar 10;348-5925660406
Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study.Ghosh, Chaitali; Hossain, Mohammad; Spriggs, Addison; Ghosh, Arnab; Grant, Gerald A; Marchi, Nicola; Perucca, Emilio; Janigro, DamirEpilepsia.2015 Mar;439-4925656284
Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers.Wang, Kezheng; Pan, Dipanjan; Schmieder, Anne H; Senpan, Angana; Hourcade, Dennis E; Pham, Christine T N; Mitchell, Lynne M; Caruthers, Shelton D; Cui, Grace; Wickline, Samuel A; Shen, Baozhong; Lanza, Gregory MNanomedicine : nanotechnology, biology, and medicine.2015 Apr;601-925652900
Developmental biology. Regional identity of gut stem cells--one gene to rule them all.Wells, James MNature reviews. Gastroenterology & hepatology.2015 Mar;125-625645971
Novel three dimensional human endocervix cultures respond to 28-day hormone treatment.Arslan, Sevim Yildiz; Yu, Yanni; Burdette, Joanne E; Pavone, Mary Ellen; Hope, Thomas J; Woodruff, Teresa K; Kim, J JulieEndocrinology.2015 Apr;1602-925635622
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.Furukawa, Masashi; Wheeler, Sarah; Clark, Amanda M; Wells, AlanPloS one.2015;e011806025635394
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.Bal-Price, Anna; Crofton, Kevin M; Leist, Marcel; Allen, Sandra; Arand, Michael; Buetler, Timo; Delrue, Nathalie; FitzGerald, Rex E; Hartung, Thomas; Heinonen, Tuula; Hogberg, Helena; Bennekou, Susanne Hougaard; Lichtensteiger, Walter; Oggier, Daniela; PaArchives of toxicology.2015 Feb;269-8725618548
A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy.Pan, Dipanjan; Kim, Benjamin; Hu, Grace; Gupta, Deepti Sood; Senpan, Angana; Yang, Xiaoxia; Schmieder, Anne; Swain, Corban; Wickline, Samuel A; Tomasson, Michael H; Lanza, Gregory MNanomedicine (London, England).2015 Jan;241-5125600969
Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status.Kumar, Kevin K; Goodwin, Cody R; Uhouse, Michael A; Bornhorst, Julia; Schwerdtle, Tanja; Aschner, Michael; McLean, John A; Bowman, Aaron BMetallomics : integrated biometal science.2015 Feb;363-7025599126
Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.Jackman, Christopher P; Shadrin, Ilya Y; Carlson, Aaron L; Bursac, NenadCurrent opinion in chemical engineering.2015 Feb;57-6425599018
TEER measurement techniques for in vitro barrier model systems.Srinivasan, Balaji; Kolli, Aditya Reddy; Esch, Mandy Brigitte; Abaci, Hasan Erbil; Shuler, Michael L; Hickman, James JJournal of laboratory automation.2015 Apr;107-2625586998
Biology coming full circle: joining the whole and the parts.Wikswo, John P; Porter, Andrew PExperimental biology and medicine (Maywood, N.J.).2015 Jan;7-Mar25583953
Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs.Madden, Lauran; Juhas, Mark; Kraus, William E; Truskey, George A; Bursac, NenadeLife.2015;e0488525575180
Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease.Wilkerson, Irene; Laban, Joshua; Mitchell, Johnathan M; Sheibani, Nader; Alcendor, Donald JJournal of neuroinflammation.2015;225573478
Nanograting structure promotes lamellipodia-based cell collective migration and wound healing.Chen, Zaozao; Atchison, Leigh; Ji, HaYeun; Leong, Kam WConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.2014;2916-925570601
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.Vega, Maria E; Giroux, Véronique; Natsuizaka, Mitsuteru; Liu, Mingen; Klein-Szanto, Andres J; Stairs, Douglas B; Nakagawa, Hiroshi; Wang, Kenneth K; Wang, Timothy C; Lynch, John P; Rustgi, Anil KCell cycle (Georgetown, Tex.).2014;3857-6625558829
ýýýý*ýýý-targeted copper nanoparticles incorporating an Sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment.Zhang, Ruiying; Pan, Dipanjan; Cai, Xin; Yang, Xiaoxia; Senpan, Angana; Allen, John S; Lanza, Gregory M; Wang, Lihong VTheranostics.2015;124-3325553103
Origin and function of cartilage stem/progenitor cells in osteoarthritis.Jiang, Yangzi; Tuan, Rocky SNature reviews. Rheumatology.2015 Apr;206-1225536487
Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion.Warita, Katsuhiko; Warita, Tomoko; Beckwitt, Colin H; Schurdak, Mark E; Vazquez, Alexei; Wells, Alan; Oltvai, Zoltán NScientific reports.2014;759325534349
Three-dimensional modeling of the human fallopian tube fimbriae.Eddie, Sharon L; Quartuccio, Suzanne M; Zhu, Jie; Shepherd, Jessica A; Kothari, Rajul; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna EGynecologic oncology.2015 Feb;348-5425527363
Ion mobility-mass spectrometry: time-dispersive instrumentation.May, Jody C; McLean, John AAnalytical chemistry.2015 Feb 3;1422-3625526595
Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells.Kulangara, Karina; Yang, Jennifer; Chellappan, Malathi; Yang, Yong; Leong, Kam WPloS one.2014;e11469825521962
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain.Kabadi, Ami M; Thakore, Pratiksha I; Vockley, Christopher M; Ousterout, David G; Gibson, Tyler M; Guilak, Farshid; Reddy, Timothy E; Gersbach, Charles AACS synthetic biology.2015 Jun 19;689-9925494287
Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis.Chakraborty, Syandan; Ji, HaYeun; Chen, Jack; Gersbach, Charles A; Leong, Kam WScientific reports.2014;740325492703
Correction of dystrophin expression in cells from duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.Ousterout, David G; Kabadi, Ami M; Thakore, Pratiksha I; Perez-Pinera, Pablo; Brown, Matthew T; Majoros, William H; Reddy, Timothy E; Gersbach, Charles AMolecular therapy : the journal of the American Society of Gene Therapy.2015 Mar;523-3225492562
Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts.Xing, Qi; Vogt, Caleb; Leong, Kam W; Zhao, FengAdvanced functional materials.2014 May 28;3027-303525484849
Tenascin-C Signaling in melanoma.Shao, Hanshuang; Kirkwood, John M; Wells, AlanCell adhesion & migration.2015;125-3025482624
Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibers.Wang, Hailong; Abhilash, A S; Chen, Christopher S; Wells, Rebecca G; Shenoy, Vivek BBiophysical journal.2014 Dec 2;2592-60325468338
Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology.May, Jody C; Goodwin, Cody R; McLean, John ACurrent opinion in biotechnology.2015 Feb;117-2125462629
A CRISPR/Cas9-based system for reprogramming cell lineage specification.Chakraborty, Syandan; Ji, HaYeun; Kabadi, Ami M; Gersbach, Charles A; Christoforou, Nicolas; Leong, Kam WStem cell reports.2014 Dec 9;940-725448066
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.Gomez, Ivan G; MacKenna, Deidre A; Johnson, Bryce G; Kaimal, Vivek; Roach, Allie M; Ren, Shuyu; Nakagawa, Naoki; Xin, Cuiyan; Newitt, Rick; Pandya, Shweta; Xia, Tai-He; Liu, Xueqing; Borza, Dorin-Bogdan; Grafals, Monica; Shankland, Stuart J; Himmelfarb, JThe Journal of clinical investigation.2015 Jan;141-5625415439
Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert.French, William R; Zimmerman, Lisa J; Schilling, Birgit; Gibson, Bradford W; Miller, Christine A; Townsend, R Reid; Sherrod, Stacy D; Goodwin, Cody R; McLean, John A; Tabb, David LJournal of proteome research.2015 Feb 6;1299-30725411686
Patterning vascular networks in vivo for tissue engineering applications.Chaturvedi, Ritika R; Stevens, Kelly R; Solorzano, Ricardo D; Schwartz, Robert E; Eyckmans, Jeroen; Baranski, Jan D; Stapleton, Sarah Chase; Bhatia, Sangeeta N; Chen, Christopher STissue engineering. Part C, Methods.2015 May;509-1725390971
Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and nontumorigenic human mesenchymal cell types.Hansen, Tyler D; Koepsel, Justin T; Le, Ngoc Nhi; Nguyen, Eric H; Zorn, Stefan; Parlato, Matthew; Loveland, Samuel G; Schwartz, Michael P; Murphy, William LBiomaterials science.2014 May;745-75625386339
Photopatterning of hydrogel scaffolds coupled to filter materials using stereolithography for perfused 3D culture of hepatocytes.Neiman, Jaclyn A Shepard; Raman, Ritu; Chan, Vincent; Rhoads, Mary G; Raredon, Micha Sam B; Velazquez, Jeremy J; Dyer, Rachel L; Bashir, Rashid; Hammond, Paula T; Griffith, Linda GBiotechnology and bioengineering.2015 Apr;777-8725384798
Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia.Brown, Jacquelyn A; Sherrod, Stacy D; Goodwin, Cody R; Brewer, Bryson; Yang, Lijie; Garbett, Krassimira A; Li, Deyu; McLean, John A; Wikswo, John P; Mirnics, KárolyJournal of neuroinflammation.2014;18325374324
ROS-cleavable proline oligomer crosslinking of polycaprolactone for pro-angiogenic host response.Lee, Sue Hyun; Boire, Timothy C; Lee, Jung Bok; Gupta, Mukesh K; Zachman, Angela L; Rath, Rutwik; Sung, Hak-JoonJournal of materials chemistry. B, Materials for biology and medicine.2014 Nov 7;7109-711325343029
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.Huebsch, Nathaniel; Loskill, Peter; Mandegar, Mohammad A; Marks, Natalie C; Sheehan, Alice S; Ma, Zhen; Mathur, Anurag; Nguyen, Trieu N; Yoo, Jennie C; Judge, Luke M; Spencer, C Ian; Chukka, Anand C; Russell, Caitlin R; So, Po-Lin; Conklin, Bruce R; HealyTissue engineering. Part C, Methods.2015 May;467-7925333967
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system.Wheeler, S E; Clark, A M; Taylor, D P; Young, C L; Pillai, V C; Stolz, D B; Venkataramanan, R; Lauffenburger, D; Griffith, L; Wells, ABritish journal of cancer.2014 Dec 9;2342-5025314052
Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells.Coskun, Suleyman; Chao, Hsu; Vasavada, Hema; Heydari, Kartoosh; Gonzales, Naomi; Zhou, Xin; de Crombrugghe, Benoit; Hirschi, Karen KCell reports.2014 Oct 23;581-9025310984
A DNA-based molecular probe for optically reporting cellular traction forces.Blakely, Brandon L; Dumelin, Christoph E; Trappmann, Britta; McGregor, Lynn M; Choi, Colin K; Anthony, Peter C; Duesterberg, Van K; Baker, Brendon M; Block, Steven M; Liu, David R; Chen, Christopher SNature methods.2014 Dec;1229-3225306545
The magic touch: endothelial cells muscle-up adipose.Martin, Kathleen A; Hirschi, Karen KCirculation research.2014 Oct 10;752-425301822
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression.Boussadia, B; Ghosh, C; Plaud, C; Pascussi, J M; de Bock, F; Rousset, M C; Janigro, D; Marchi, NNeuroscience.2014 Oct 2;124-13425280786
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.Spencer, C Ian; Baba, Shiro; Nakamura, Kenta; Hua, Ethan A; Sears, Marie A F; Fu, Chi-cheng; Zhang, Jianhua; Balijepalli, Sadguna; Tomoda, Kiichiro; Hayashi, Yohei; Lizarraga, Paweena; Wojciak, Julianne; Scheinman, Melvin M; Aalto-Setälä, Katriina; MakielStem cell reports.2014 Aug 12;269-8125254341
Physicochemical signatures of nanoparticle-dependent complement activation.Thomas, Dennis G; Chikkagoudar, Satish; Heredia-Langer, Alejandro; Tardiff, Mark F; Xu, Zhixiang; Hourcade, Dennis E; Pham, Christine T N; Lanza, Gregory M; Weinberger, Kilian Q; Baker, Nathan AComputational science & discovery.2014 Mar 21;1500325254068
Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases.Hines, Kelly M; Ballard, Billy R; Marshall, Dana R; McLean, John AMolecular bioSystems.2014 Nov;2827-3725212505
Design of growth factor sequestering biomaterials.Belair, David G; Le, Ngoc Nhi; Murphy, William LChemical communications (Cambridge, England).2014 Dec 25;15651-6825182455
Balanced UTE-SSFP for 19F MR imaging of complex spectra.Goette, Matthew J; Keupp, Jochen; Rahmer, Jürgen; Lanza, Gregory M; Wickline, Samuel A; Caruthers, Shelton DMagnetic resonance in medicine.2015 Aug;537-4325163853
Angiogenesis and airway reactivity in asthmatic Brown Norway rats.Wagner, Elizabeth M; Jenkins, John; Schmieder, Anne; Eldridge, Lindsey; Zhang, Qiong; Moldobaeva, Aigul; Zhang, Huiying; Allen, John S; Yang, Xiaoxia; Mitzner, Wayne; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory MAngiogenesis.2015 Jan;11-Jan25149641
Current progress in Reactive Oxygen Species (ROS)-Responsive materials for biomedical applications.Lee, Sue Hyun; Gupta, Mukesh K; Bang, Jae Beum; Bae, Hojae; Sung, Hak-JoonAdvanced healthcare materials.2013;908-1525136729
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems.Shlomai, Amir; Schwartz, Robert E; Ramanan, Vyas; Bhatta, Ankit; de Jong, Ype P; Bhatia, Sangeeta N; Rice, Charles MProceedings of the National Academy of Sciences of the United States of America.2014 Aug 19;12193-825092305
Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes.Freytes, Donald O; O'Neill, John D; Duan-Arnold, Yi; Wrona, Emily A; Vunjak-Novakovic, GordanaMethods in molecular biology (Clifton, N.J.).2014;69-8125070328
Developing microphysiological systems for use as regulatory tools--challenges and opportunities.Andersen, Melvin E; Betts, Kellyn; Dragan, Yvonne; Fitzpatrick, Suzanne; Goodman, Jesse L; Hartung, Thomas; Himmelfarb, Jonathan; Ingber, Donald E; Jacobs, Abigail; Kavlock, Robert; Kolaja, Kyle; Stevens, James L; Tagle, Dan; Lansing Taylor, D; ThrockmortALTEX.2014;364-725061900
Cell and tissue engineering for liver disease.Bhatia, Sangeeta N; Underhill, Gregory H; Zaret, Kenneth S; Fox, Ira JScience translational medicine2014 Jul 16245sr225031271
Tissue-engineered microenvironment systems for modeling human vasculature.Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, ThomasExperimental biology and medicine (Maywood, N.J.).2014 Sep;1264-7125030480
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.Alépée, Natalie; Bahinski, Anthony; Daneshian, Mardas; De Wever, Bart; Fritsche, Ellen; Goldberg, Alan; Hansmann, Jan; Hartung, Thomas; Haycock, John; Hogberg, Helena; Hoelting, Lisa; Kelm, Jens M; Kadereit, Suzanne; McVey, Emily; Landsiedel, Robert; LeisALTEX.2014;441-7725027500
Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases.Alexander, Peter G; Gottardi, Riccardo; Lin, Hang; Lozito, Thomas P; Tuan, Rocky SExperimental biology and medicine (Maywood, N.J.).2014 Sep;1080-9524994814
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury.Esch, Mandy B; Mahler, Gretchen J; Stokol, Tracy; Shuler, Michael LLab on a chip.2014 Aug 21;3081-9224970651
Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use.Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Argueta, Lissenya B; Eastaway, Adriene; Cortiella, JoaquinExperimental biology and medicine (Maywood, N.J.).2014 Sep;1135-6924962174
Using physiologically-based pharmacokinetic-guided ''body-on-a-chip'' systems to predict mammalian response to drug and chemical exposure.Sung, Jong Hwan; Srinivasan, Balaji; Esch, Mandy Brigitte; McLamb, William T; Bernabini, Catia; Shuler, Michael L; Hickman, James JExperimental biology and medicine (Maywood, N.J.).2014 Sep;1225-3924951471
Challenges and promises in modeling dermatologic disorders with bioengineered skin.Eungdamrong, Narat J; Higgins, Claire; Guo, Zongyou; Lee, Wen-Han; Gillette, Brian; Sia, Samuel; Christiano, Angela MExperimental biology and medicine (Maywood, N.J.).2014 Sep;1215-2424951469
Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide.Zhou, Hui-fang; Yan, Huimin; Hu, Ying; Springer, Luke E; Yang, Xiaoxia; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T NACS nano2014 Jul 227305-1724941020
A novel ultrathin collagen nanolayer assembly for 3-D microtissue engineering: Layer-by-layer collagen deposition for long-term stable microfluidic hepatocyte culture.McCarty, William J; Usta, O Berk; Luitje, Martha; Bale, Shyam Sundhar; Bhushan, Abhinav; Hegde, Manjunath; Golberg, Inna; Jindal, Rohit; Yarmush, Martin LTechnology.2014 Mar;67-7424932459
Physiology and metabolism of tissue-engineered skeletal muscle.Cheng, Cindy S; Davis, Brittany N J; Madden, Lauran; Bursac, Nenad; Truskey, George AExperimental biology and medicine (Maywood, N.J.).2014 Sep;1203-1424912506
Biological and medical applications of a brain-on-a-chip.Pamies, David; Hartung, Thomas; Hogberg, Helena TExperimental biology and medicine (Maywood, N.J.).2014 Sep;1096-10724912505
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro.Smith, A S T; Long, C J; Pirozzi, K; Najjar, S; McAleer, C; Vandenburgh, H H; Hickman, J JJournal of biotechnology.2014 Sep 20;15-824909944
Induced pluripotent stem cells for regenerative medicine.Hirschi, Karen K; Li, Song; Roy, KrishnenduAnnual review of biomedical engineering.2014 Jul 11;277-9424905879
Systems-level view of cocaine addiction: the interconnection of the immune and nervous systems.Marasco, Christina C; Goodwin, Cody R; Winder, Danny G; Schramm-Sapyta, Nicole L; McLean, John A; Wikswo, John PExperimental biology and medicine (Maywood, N.J.).2014 Nov;1433-4224903164
Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover.Evans, J Corey; Hines, Kelly M; Forsythe, Jay G; Erdogan, Begum; Shi, Mingjian; Hill, Salisha; Rose, Kristie L; McLean, John A; Webb, Donna JJournal of proteome research.2014 Jul 3;3303-1324874604
Ovarian cancer in endometriosis: clinical and molecular aspects.Lyttle, B; Bernardi, L; Pavone, M EMinerva ginecologica2014 Apr155-6424848074
Fluid shear stress threshold regulates angiogenic sprouting.Galie, Peter A; Nguyen, Duc-Huy T; Choi, Colin K; Cohen, Daniel M; Janmey, Paul A; Chen, Christopher SProceedings of the National Academy of Sciences of the United States of America2014 Jun 37968-7324843171
Intracerebral hemorrhage mortality is not changing despite declining incidence.Zahuranec, Darin B; Lisabeth, Lynda D; Sanchez, Brisa N; Smith, Melinda A; Brown, Devin L; Garcia, Nelda M; Skolarus, Lesli E; Meurer, William J; Burke, James F; Adelman, Eric E; Morgenstern, Lewis BNeurology2014 Jun 172180-624838789
Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks.Zhao, XuanheSoft matter.2014 Feb 7;672-8724834901
MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation.Bulte, Jeff W M; Schmieder, Anne H; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Lanza, Gregory MNanomedicine : nanotechnology, biology, and medicine.2014 Oct;1385-824832959
Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1?.Lin, Hang; Lozito, Thomas P; Alexander, Peter G; Gottardi, Riccardo; Tuan, Rocky SMolecular pharmaceutics.2014 Jul 7;2203-1224830762
Approaching the in vitro clinical trial: engineering organs on chips.Capulli, A K; Tian, K; Mehandru, N; Bukhta, A; Choudhury, S F; Suchyta, M; Parker, K KLab on a chip.2014 Sep 7;3181-624828385
A microphysiological system model of therapy for liver micrometastases.Clark, Amanda M; Wheeler, Sarah E; Taylor, Donald P; Pillai, Venkateswaran C; Young, Carissa L; Prantil-Baun, Rachelle; Nguyen, Transon; Stolz, Donna B; Borenstein, Jeffrey T; Lauffenburger, Douglas A; Venkataramanan, Raman; Griffith, Linda G; Wells, AlanExperimental biology and medicine (Maywood, N.J.).2014 Sep;1170-924821820
Polymeric stent materials dysregulate macrophage and endothelial cell functions: implications for coronary artery stent.Wang, Xintong; Zachman, Angela L; Chun, Young Wook; Shen, Fang-Wen; Hwang, Yu-Shik; Sung, Hak-JoonInternational journal of cardiology.2014 Jul 1;688-9524820736
Materials innovation for co-delivery of diverse therapeutic cargos.Godsey, Megan E; Suryaprakash, Smruthi; Leong, Kam WRSC advances.2013 Dec 21;24794-2481124818000
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.Wang, Gang; McCain, Megan L; Yang, Luhan; He, Aibin; Pasqualini, Francesco Silvio; Agarwal, Ashutosh; Yuan, Hongyan; Jiang, Dawei; Zhang, Donghui; Zangi, Lior; Geva, Judith; Roberts, Amy E; Ma, Qing; Ding, Jian; Chen, Jinghai; Wang, Da-Zhi; Li, Kai; Wang,Nature medicine.2014 Jun;616-2324813252
Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits.Puvenna, Vikram; Brennan, Chanda; Shaw, Gerald; Yang, Cui; Marchi, Nicola; Bazarian, Jeffrey J; Merchant-Borna, Kian; Janigro, DamirPloS one.2014;e9629624806476
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.Ebrahimkhani, Mohammad R; Young, Carissa L; Lauffenburger, Douglas A; Griffith, Linda G; Borenstein, Jeffrey TDrug discovery today2014 Jun754-6224793141
Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems.Hartman, Kira G; Bortner Jr, James D; Falk, Gary W; Ginsberg, Gregory G; Jhala, Nirag; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John PExperimental biology and medicine (Maywood, N.J.).2014 Sep;1108-2324781339
Dynamic interplay of flow and collagen stabilizes primary hepatocytes culture in a microfluidic platform.Hegde, Manjunath; Jindal, Rohit; Bhushan, Abhinav; Bale, Shyam Sundhar; McCarty, William J; Golberg, Inna; Usta, O Berk; Yarmush, Martin LLab on a chip.2014 Jun 21;2033-924770663
Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research.Abrams, Julian A; Appelman, Henry D; Beer, David G; Berry, Lynne D; Chak, Amitabh; Falk, Gary W; Fitzgerald, Rebecca C; Ginsberg, Gregory G; Grady, William M; Joshi, Bishnu P; Lynch, John P; Markowitz, Sanford; Richmond, Ellen S; Rustgi, Anil K; Seibel, EGastroenterology.2014 Jun;1586-9024768332
In vitro platforms for evaluating liver toxicity.Bale, Shyam Sundhar; Vernetti, Lawrence; Senutovitch, Nina; Jindal, Rohit; Hegde, Manjunath; Gough, Albert; McCarty, William J; Bakan, Ahmet; Bhushan, Abhinav; Shun, Tong Y; Golberg, Inna; DeBiasio, Richard; Usta, O Berk; Taylor, D Lansing; Yarmush, MartiExperimental biology and medicine (Maywood, N.J.).2014 Sep;1180-9124764241
A three-dimensional in vitro model of tumor cell intravasation.Ehsan, Seema M; Welch-Reardon, Katrina M; Waterman, Marian L; Hughes, Christopher C W; George, Steven CIntegrative biology : quantitative biosciences from nano to macro.2014 Jun;603-1024763498
Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC? signaling.Cha, Boyoung; Chen, Tiane; Sarker, Rafiquel; Yang, Jianbo; Raben, Daniel; Tse, C Ming; Kovbasnjuk, Olga; Donowitz, MarkAmerican journal of physiology. Cell physiology.2014 Jul 1;C55-6524760985
A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening.Heylman, Christopher; Sobrino, Agua; Shirure, Venktesh S; Hughes, Christopher Cw; George, Steven CExperimental biology and medicine (Maywood, N.J.).2014 Sep;1240-5424740872
Microphysiological modeling of the reproductive tract: A fertile endeavor.Eddie, Sharon L; Kim, J Julie; Woodruff, Teresa K; Burdette, Joanna EExperimental biology and medicine (Maywood, N.J.)2014 Apr 15NULL24737736
Microscale technologies for regulating human stem cell differentiation.Cimetta, Elisa; Vunjak-Novakovic, GordanaExperimental biology and medicine (Maywood, N.J.).2014 Sep;1255-6324737735
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues.McCain, Megan L; Agarwal, Ashutosh; Nesmith, Haley W; Nesmith, Alexander P; Parker, Kevin KitBiomaterials.2014 Jul;5462-7124731714
Integrating in vitro organ-specific function with the microcirculation.Moya, Monica L; George, Steven CCurrent opinion in chemical engineering.2014 Feb 1;103-11124729953
Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using *(v)*ýýý-targeted theranostic nanoparticles.Pan, Dipanjan; Schmieder, Anne H; Wang, Kezheng; Yang, Xiaoxia; Senpan, Angana; Cui, Grace; Killgore, Kendall; Kim, Benjamin; Allen, John S; Zhang, Huiying; Caruthers, Shelton D; Shen, Baozhong; Wickline, Samuel A; Lanza, Gregory MTheranostics2014565-7824723979
3D - a new dimension of in vitro research.Hartung, ThomasAdvanced drug delivery reviews.2014 Apr;vi24721291
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract.Foulke-Abel, Jennifer; In, Julie; Kovbasnjuk, Olga; Zachos, Nicholas C; Ettayebi, Khalil; Blutt, Sarah E; Hyser, Joseph M; Zeng, Xi-Lei; Crawford, Sue E; Broughman, James R; Estes, Mary K; Donowitz, MarkExperimental biology and medicine (Maywood, N.J.).2014 Sep;1124-3424719375
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons.Kulangara, Karina; Adler, Andrew F; Wang, Hong; Chellappan, Malathi; Hammett, Ellen; Yasuda, Ryohei; Leong, Kam WBiomaterials.2014 Jul;5327-3624709523
Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities.Smirnova, Lena; Hogberg, Helena T; Leist, Marcel; Hartung, ThomasALTEX2014129-5624687333
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.McCain, Megan L; Yuan, Hongyan; Pasqualini, Francesco S; Campbell, Patrick H; Parker, Kevin KitAmerican journal of physiology. Heart and circulatory physiology.2014 Jun 1;H1525-3924682394
Structural characterization of methylenedianiline regioisomers by ion mobility-mass spectrometry, tandem mass spectrometry, and computational strategies: I. Electrospray spectra of 2-ring isomers.Forsythe, Jay G; Stow, Sarah M; Nefzger, Hartmut; Kwiecien, Nicholas W; May, Jody C; McLean, John A; Hercules, David MAnalytical chemistry.2014 May 6;4362-7024678803
Quality metrics for stem cell-derived cardiac myocytes.Sheehy, Sean P; Pasqualini, Francesco; Grosberg, Anna; Park, Sung Jin; Aratyn-Schaus, Yvonne; Parker, Kevin KitStem cell reports.2014 Mar 11;282-9424672752
Engineering Liver.Griffith, Linda G; Wells, Alan; Stolz, Donna BeerHepatology (Baltimore, Md.)2014 Mar 26NULL24668880
Antagonizing the *v *3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading.Tomlinson, Ryan E; Schmieder, Anne H; Quirk, James D; Lanza, Gregory M; Silva, Matthew JJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.2014 Sep;1970-8024644077
Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening.Zhao, Ruogang; Chen, Christopher S; Reich, Daniel HBiomaterials.2014 Jun;5056-6424630092
Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor.Diederichs, Solvig; Tuan, Rocky SStem cells and development.2014 Jul 15;1594-61024625206
The mitogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase (ERK) are involved in hepatocyte-mediated phenotypic switching in prostate cancer cells.Ma, Bo; Wells, AlanThe Journal of biological chemistry.2014 Apr 18;11153-6124619413
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition.Taylor, Donald P; Clark, Amanda; Wheeler, Sarah; Wells, AlanBreast cancer research and treatment2014 Apr551-6024610032
Bioreactor technologies to support liver function in vitro.Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B; Hughes, David J; Griffith, Linda GAdvanced drug delivery reviews2014 Apr132-5724607703
Myocardial tissue engineering: in vitro models.Vunjak Novakovic, Gordana; Eschenhagen, Thomas; Mummery, ChristineCold Spring Harbor perspectives in medicine.2014 Mar;24591534
Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain.Crowder, Spencer W; Balikov, Daniel A; Hwang, Yu-Shik; Sung, Hak-JoonCurrent pathobiology reports.2014 Mar;33-4024587979
Cartilage tissue engineering application of injectable gelatin hydrogel with in situ visible-light-activated gelation capability in both air and aqueous solution.Lin, Hang; Cheng, Anthony Wai-Ming; Alexander, Peter G; Beck, Angela M; Tuan, Rocky STissue engineering. Part A.2014 Sep;2402-1124575844
Three-dimensional paper-based model for cardiac ischemia.Mosadegh, Bobak; Dabiri, Borna E; Lockett, Matthew R; Derda, Ratmir; Campbell, Patrick; Parker, Kevin Kit; Whitesides, George MAdvanced healthcare materials.2014 Jul;1036-4324574054
Mouse liver repopulation with hepatocytes generated from human fibroblasts.Zhu, Saiyong; Rezvani, Milad; Harbell, Jack; Mattis, Aras N; Wolfe, Alan R; Benet, Leslie Z; Willenbring, Holger; Ding, ShengNature.2014 Apr 3;93-724572354
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans.Bhushan, Abhinav; Senutovitch, Nina; Bale, Shyam S; McCarty, William J; Hegde, Manjunath; Jindal, Rohit; Golberg, Inna; Berk Usta, O; Yarmush, Martin L; Vernetti, Lawrence; Gough, Albert; Bakan, Ahmet; Shun, Tong Ying; DeBiasio, Richard; Lansing Taylor, DStem cell research & therapy.2013;S1624565476
An integrated in vitro model of perfused tumor and cardiac tissue.Moya, Monica; Tran, David; George, Steven CStem cell research & therapy.2013;S1524565445
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.Mathur, Anurag; Loskill, Peter; Hong, Soongweon; Lee, Jae; Marcus, Sivan G; Dumont, Laure; Conklin, Bruce R; Willenbring, Holger; Lee, Luke P; Healy, Kevin EStem cell research & therapy.2013;S1424565415
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment.Laronda, Monica M; Burdette, Joanna E; Kim, J; Woodruff, Teresa KStem cell research & therapy2013S1324565375
A human pluripotent stem cell platform for assessing developmental neural toxicity screening.Hou, Zhonggang; Zhang, Jue; Schwartz, Michael P; Stewart, Ron; Page, C David; Murphy, William L; Thomson, James AStem cell research & therapy.2013;S1224565336
All-human microphysical model of metastasis therapy.Wheeler, Sarah E; Borenstein, Jeffrey T; Clark, Amanda M; Ebrahimkhani, Mohammad R; Fox, Ira J; Griffith, Linda; Inman, Walker; Lauffenburger, Douglas; Nguyen, Transon; Pillai, Venkateswaran C; Prantil-Baun, Rachelle; Stolz, Donna B; Taylor, Donald; UlricStem cell research & therapy.2013;S1124565274
Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing.Truskey, George A; Achneck, Hardean E; Bursac, Nenad; Chan, Hon; Cheng, Cindy S; Fernandez, Cristina; Hong, Sungmin; Jung, Youngmee; Koves, Tim; Kraus, William E; Leong, Kam; Madden, Lauran; Reichert, William M; Zhao, XuanheStem cell research & therapy.2013;S1024565225
Building additional complexity to in vitro-derived intestinal tissues.Brugmann, Samantha A; Wells, James MStem cell research & therapy.2013;S124565179
Microphysiological systems and low-cost microfluidic platform with analytics.Smith, Alec S T; Long, Christopher J; Berry, Bonnie J; McAleer, Christopher; Stancescu, Maria; Molnar, Peter; Miller, Paula G; Esch, Mandy B; Prot, Jean-Matthieu; Hickman, James J; Shuler, Michael LStem cell research & therapy.2013;S924565109
HeLiVa platform: integrated heart-liver-vascular systems for drug testing in human health and disease.Vunjak-Novakovic, Gordana; Bhatia, Sangeeta; Chen, Christopher; Hirschi, KarenStem cell research & therapy2013S824565063
Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology.Nichols, Joan E; Niles, Jean A; Vega, Stephanie P; Cortiella, JoaquinStem cell research & therapy.2013;S724565038
Three-dimensional osteochondral microtissue to model pathogenesis of osteoarthritis.Lozito, Thomas P; Alexander, Peter G; Lin, Hang; Gottardi, Riccardo; Cheng, Anthony Wai-Ming; Tuan, Rocky SStem cell research & therapy.2013;S624564995
Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems.Hartman, Kira G; Bortner, James D; Falk, Gary W; Yu, Jian; Martín, Martín G; Rustgi, Anil K; Lynch, John PStem cell research & therapy.2013;S524564965
Toward a 3D model of human brain development for studying gene/environment interactions.Hogberg, Helena T; Bressler, Joseph; Christian, Kimberly M; Harris, Georgina; Makri, Georgia; O'Driscoll, Cliona; Pamies, David; Smirnova, Lena; Wen, Zhexing; Hartung, ThomasStem cell research & therapy.2013;S424564953
Human enteroids: preclinical models of non-inflammatory diarrhea.Kovbasnjuk, Olga; Zachos, Nicholas C; In, Julie; Foulke-Abel, Jennifer; Ettayebi, Khalil; Hyser, Joseph M; Broughman, James R; Zeng, Xi-Lei; Middendorp, Sabine; de Jonge, Hugo R; Estes, Mary K; Donowitz, MarkStem cell research & therapy.2013;S324564938
Building a microphysiological skin model from induced pluripotent stem cells.Guo, Zongyou; Higgins, Claire A; Gillette, Brian M; Itoh, Munenari; Umegaki, Noriko; Gledhill, Karl; Sia, Samuel K; Christiano, Angela MStem cell research & therapy.2013;S224564920
Neurovascular unit on a chip: implications for translational applications.Alcendor, Donald J; Block 3rd, Frank E; Cliffel, David E; Daniels, John Scott; Ellacott, Kate L J; Goodwin, Cody R; Hofmeister, Lucas H; Li, Deyu; Markov, Dmitry A; May, Jody C; McCawley, Lisa J; McLaughlin, BethAnn; McLean, John A; Niswender, Kevin D; PeStem cell research & therapy.2013;S1824564885
Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.Kelly, Edward J; Wang, Zhican; Voellinger, Jenna L; Yeung, Cathy K; Shen, Danny D; Thummel, Kenneth E; Zheng, Ying; Ligresti, Giovanni; Eaton, David L; Muczynski, Kimberly A; Duffield, Jeremy S; Neumann, Thomas; Tourovskaia, Anna; Fauver, Mark; Kramer, GrStem cell research & therapy.2013;S1724564863
Annotating the structure and components of a nanoparticle formulation using computable string expressions.Thomas, Dennis G; Chikkagoudar, Satish; Chappell, Alan R; Baker, Nathan AProceedings. IEEE International Conference on Bioinformatics and Biomedicine.2012 Dec 31;889-89424533226
Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs).Fernandez, Cristina E; Achneck, Hardean E; Reichert, William M; Truskey, George ACurrent opinion in chemical engineering.2014 Feb 1;83-9024511460
Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.Li, Cheri Yingjie; Stevens, Kelly R; Schwartz, Robert E; Alejandro, Brian Steven; Huang, Joanne H; Bhatia, Sangeeta NTissue engineering. Part A2014 Feb 5NULL24498910
Physical influences on stem cells.Vunjak-Novakovic, GordanaStem cell research & therapy.2013;15324476419
Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons.Pan, Dipanjan; Schirra, Carsten O; Wickline, Samuel A; Lanza, Gregory MContrast media & molecular imaging2014 Jan-Feb13-2524470291
Molecular imaging with computed tomography.Lanza, Gregory M; Pan, DipanjanContrast media & molecular imaging2014 Jan-Feb2-Jan24470289
Nanoinformatics workshop report: Current resources, community needs, and the proposal of a collaborative framework for data sharing and information integration.Harper, Stacey L; Hutchison, James E; Baker, Nathan; Ostraat, Michele; Tinkle, Sally; Steevens, Jeffrey; Hoover, Mark D; Adamick, Jessica; Rajan, Krishna; Gaheen, Sharon; Cohen, Yoram; Nel, Andre; Cachau, Raul E; Tuominen, MarkComputational science & discovery20131400824454543
Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer.May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, JoAnalytical chemistry.2014 Feb 18;2107-1624446877
Mapping the human toxome by systems toxicology.Bouhifd, Mounir; Hogberg, Helena T; Kleensang, Andre; Maertens, Alexandra; Zhao, Liang; Hartung, ThomasBasic & clinical pharmacology & toxicology2014 Jul24-3124443875
The current status of iPS cells in cardiac research and their potential for tissue engineering and regenerative medicine.Martins, Ana M; Vunjak-Novakovic, Gordana; Reis, Rui LStem cell reviews2014 Apr177-9024425421
How multi-organ microdevices can help foster drug development.Esch, Mandy B; Smith, Alec S T; Prot, Jean-Matthieu; Oleaga, Carlota; Hickman, James J; Shuler, Michael LAdvanced drug delivery reviews.2014 Apr;158-6924412641
Label-free evaluation of angiogenic sprouting in microengineered devices using ultrahigh-resolution optical coherence microscopy.Li, Fengqiang; Xu, Ting; Nguyen, Duc-Huy T; Huang, Xiaolei; Chen, Christopher S; Zhou, ChaoJournal of biomedical optics.2014 Jan;1600624395588
Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles.Rangarajan, Swathi; Madden, Lauran; Bursac, NenadAnnals of biomedical engineering.2014 Jul;1391-40524366526
Physiologically relevant organs on chips.Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke PBiotechnology journal.2014 Jan;16-2724357624
Inflammatory pathways of seizure disorders.Marchi, Nicola; Granata, Tiziana; Janigro, DamirTrends in neurosciences.2014 Feb;55-6524355813
Assessing the barriers to image-guided drug delivery.Lanza, Gregory M; Moonen, Chrit; Baker Jr, James R; Chang, Esther; Cheng, Zheng; Grodzinski, Piotr; Ferrara, Katherine; Hynynen, Kullervo; Kelloff, Gary; Lee, Yong-Eun Koo; Patri, Anil K; Sept, David; Schnitzer, Jan E; Wood, Bradford J; Zhang, Miqin; ZhenWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2014 Jan-Feb14-Jan24339356
Matrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasion.Grahovac, Jelena; Wells, AlanLaboratory investigation; a journal of technical methods and pathology2014 Jan31-4024247562
Application of a hemolysis assay for analysis of complement activation by perfluorocarbon nanoparticles.Pham, Christine T N; Thomas, Dennis G; Beiser, Julia; Mitchell, Lynne M; Huang, Jennifer L; Senpan, Angana; Hu, Grace; Gordon, Mae; Baker, Nathan A; Pan, Dipanjan; Lanza, Gregory M; Hourcade, Dennis ENanomedicine : nanotechnology, biology, and medicine2013 Nov 8NULL24211337
Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption.Singh, Varsha; Yang, Jianbo; Chen, Tiane-e; Zachos, Nicholas C; Kovbasnjuk, Olga; Verkman, Alan S; Donowitz, MarkClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.2014 Jan;27-3124184676
Microfluidic device to culture 3D in vitro human capillary networks.Moya, Monica L; Alonzo, Luis F; George, Steven CMethods in molecular biology (Clifton, N.J.).2014;21-724155229
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).Itoh, Munenari; Umegaki-Arao, Noriko; Guo, Zongyou; Liu, Liang; Higgins, Claire A; Christiano, Angela MPloS one.2013;e7767324147053
Microfabrication of human organs-on-chips.Huh, Dongeun; Kim, Hyun Jung; Fraser, Jacob P; Shea, Daniel E; Khan, Mohammed; Bahinski, Anthony; Hamilton, Geraldine A; Ingber, Donald ENature protocols2013 Nov2135-5724113786
Portable bioreactor for perfusion and electrical stimulation of engineered cardiac tissue.Tandon, Nina; Taubman, Alanna; Cimetta, Elisa; Saccenti, Laetitia; Vunjak-Novakovic, GordanaConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference.2013;6219-2324111161
Variation in diffusion of gases through PDMS due to plasma surface treatment and storage conditions.Markov, Dmitry A; Lillie, Elizabeth M; Garbett, Shawn P; McCawley, Lisa JBiomedical microdevices.2014 Feb;91-624065585
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix.Yang, Guang; Rothrauff, Benjamin B; Lin, Hang; Gottardi, Riccardo; Alexander, Peter G; Tuan, Rocky SBiomaterials.2013 Dec;9295-30624044998
The established status epilepticus trial 2013.Bleck, Thomas; Cock, Hannah; Chamberlain, James; Cloyd, James; Connor, Jason; Elm, Jordan; Fountain, Nathan; Jones, Elizabeth; Lowenstein, Daniel; Shinnar, Shlomo; Silbergleit, Robert; Treiman, David; Trinka, Eugen; Kapur, JaideepEpilepsia2013 Sep89-9224001084
A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches.Janigro, Damir; Iffland 2nd, Philip H; Marchi, Nicola; Granata, TizianaEpilepsia.2013 Sep;30-224001067
A brief account of nanoparticle contrast agents for photoacoustic imaging.Pan, Dipanjan; Kim, Benjamin; Wang, Lihong V; Lanza, Gregory MWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2013 Nov-Dec517-4323983210
Clear castable polyurethane elastomer for fabrication of microfluidic devices.Domansky, Karel; Leslie, Daniel C; McKinney, James; Fraser, Jacob P; Sliz, Josiah D; Hamkins-Indik, Tiama; Hamilton, Geraldine A; Bahinski, Anthony; Ingber, Donald ELab on a chip2013 Oct 73956-6423954953
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis.Hou, Zhonggang; Zhang, Yan; Propson, Nicholas E; Howden, Sara E; Chu, Li-Fang; Sontheimer, Erik J; Thomson, James AProceedings of the National Academy of Sciences of the United States of America.2013 Sep 24;15644-923940360
Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase.Coulter, Jonathan B; O'Driscoll, Cliona M; Bressler, Joseph PThe Journal of biological chemistry.2013 Oct 4;28792-80023940045
Bioengineering heart tissue for in vitro testing.Cimetta, Elisa; Godier-Furnemont, Amandine; Vunjak-Novakovic, GordanaCurrent opinion in biotechnology2013 Aug 6NULL23932513
A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells.Magness, Scott T; Puthoff, Brent J; Crissey, Mary Ann; Dunn, James; Henning, Susan J; Houchen, Courtney; Kaddis, John S; Kuo, Calvin J; Li, Linheng; Lynch, John; Martin, Martin G; May, Randal; Niland, Joyce C; Olack, Barbara; Qian, Dajun; Stelzner, MatthiAmerican journal of physiology. Gastrointestinal and liver physiology.2013 Oct 15;G542-5123928185
Characterization of early neovascular response to acute lung ischemia using simultaneous (19)F/ (1)H MR molecular imaging.Schmieder, Anne H; Wang, Kezheng; Zhang, Huiying; Senpan, Angana; Pan, Dipanjan; Keupp, Jochen; Caruthers, Shelton D; Wickline, Samuel A; Shen, Baozhong; Wagner, Elizabeth M; Lanza, Gregory MAngiogenesis2014 Jan51-6023918207
Transplantable liver organoids made from only three ingredients.Willenbring, Holger; Soto-Gutierrez, AlejandroCell stem cell.2013 Aug 1;139-4023910079
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.Johnston, S Claiborne; Easton, J Donald; Farrant, Mary; Barsan, William; Battenhouse, Holly; Conwit, Robin; Dillon, Catherine; Elm, Jordan; Lindblad, Anne; Morgenstern, Lewis; Poisson, Sharon N; Palesch, YukoInternational journal of stroke : official journal of the International Stroke Society2013 Aug479-8323879752
Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains.Ghosh, Chaitali; Hossain, Mohammed; Puvenna, Vikram; Martinez-Gonzalez, Jorge; Alexopolous, Andreas; Janigro, Damir; Marchi, NicolaEpilepsia.2013 Sep;1562-7023865846
Look back in anger - what clinical studies tell us about preclinical work.Hartung, ThomasALTEX2013275-9123861075
Spinal Cord Injury Neuroprotection and the Promise of Flexible Adaptive Clinical Trials.Meurer, William J; Barsan, William GWorld neurosurgery2013 Jul 9NULL23851207
Bayesian adaptive trials offer advantages in comparative effectiveness trials: an example in status epilepticus.Connor, Jason T; Elm, Jordan J; Broglio, Kristine R; ESETT and ADAPT-IT InvestigatorsJournal of clinical epidemiology2013 AugS130-723849147
Scaling and systems biology for integrating multiple organs-on-a-chip.Wikswo, John P; Curtis, Erica L; Eagleton, Zachary E; Evans, Brian C; Kole, Ayeeshik; Hofmeister, Lucas H; Matloff, William JLab on a chip2013 Aug 133496-51123828456
Microfluidic heart on a chip for higher throughput pharmacological studies.Agarwal, Ashutosh; Goss, Josue Adrian; Cho, Alexander; McCain, Megan Laura; Parker, Kevin KitLab on a chip2013 Aug 133599-60823807141
The Dormancy Dilemma: Quiescence versus Balanced Proliferation.Wells, Alan; Griffith, Linda; Wells, Jakob Z; Taylor, Donald PCancer research2013 Jun 2123794703
Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients.Baker, Brendon M; Trappmann, Britta; Stapleton, Sarah C; Toro, Esteban; Chen, Christopher SLab on a chip.2013 Aug 21;3246-5223787488
Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues.Christoforou, Nicolas; Liau, Brian; Chakraborty, Syandan; Chellapan, Malathi; Bursac, Nenad; Leong, Kam WPloS one.2013;e6596323785459
Changes in macrophage phenotype as the immune response evolves.Lichtnekert, Julia; Kawakami, Takahisa; Parks, William C; Duffield, Jeremy SCurrent opinion in pharmacology.2013 Aug;555-6423747023
Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts.Shi, Mingjian; Majumdar, Devi; Gao, Yandong; Brewer, Bryson M; Goodwin, Cody R; McLean, John A; Li, Deyu; Webb, Donna JLab on a chip.2013 Aug 7;3008-2123736663
A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays.Hsu, Yu-Hsiang; Moya, Monica L; Hughes, Christopher C W; George, Steven C; Lee, Abraham PLab on a chip.2013 Aug 7;2990-823723013
Pericytes in kidney fibrosis.Ren, Shuyu; Duffield, Jeremy SCurrent opinion in nephrology and hypertension.2013 Jul;471-8023722183
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip.McCain, Megan L; Sheehy, Sean P; Grosberg, Anna; Goss, Josue A; Parker, Kevin KitProceedings of the National Academy of Sciences of the United States of America.2013 Jun 11;9770-523716679
Engineering skeletal muscle repair.Juhas, Mark; Bursac, NenadCurrent opinion in biotechnology.2013 Oct;880-623711735
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells.Ma, Xiaocui; Duan, Yuyou; Tschudy-Seney, Benjamin; Roll, Garrett; Behbahan, Iman Saramipoor; Ahuja, Tijess P; Tolstikov, Vladimir; Wang, Charles; McGee, Jeannine; Khoobyari, Shiva; Nolta, Jan A; Willenbring, Holger; Zern, Mark AStem cells translational medicine.2013 Jun;409-1923681950
Mechanistic validation.Hartung, Thomas; Hoffmann, Sebastian; Stephens, MartinALTEX2013119-3023665802
Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes.Zhang, Donghui; Shadrin, Ilya Y; Lam, Jason; Xian, Hai-Qian; Snodgrass, H Ralph; Bursac, NenadBiomaterials.2013 Jul;5813-2023642535
Production and assessment of decellularized pig and human lung scaffolds.Nichols, Joan E; Niles, Jean; Riddle, Michael; Vargas, Gracie; Schilagard, Tuya; Ma, Liang; Edward, Kert; La Francesca, Saverio; Sakamoto, Jason; Vega, Stephanie; Ogadegbe, Marie; Mlcak, Ronald; Deyo, Donald; Woodson, Lee; McQuitty, Christopher; Lick, ScoTissue engineering. Part A.2013 Sep;2045-6223638920
Three-dimensional graphene foams promote osteogenic differentiation of human mesenchymal stem cells.Crowder, Spencer W; Prasai, Dhiraj; Rath, Rutwik; Balikov, Daniel A; Bae, Hojae; Bolotin, Kirill I; Sung, Hak-JoonNanoscale.2013 May 21;4171-623592029
A therapy for liver failure found in the JNK yard.Willenbring, Holger; Grompe, MarkusCell.2013 Apr 11;283-423582318
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro.Nguyen, Duc-Huy T; Stapleton, Sarah C; Yang, Michael T; Cha, Susie S; Choi, Colin K; Galie, Peter A; Chen, Christopher SProceedings of the National Academy of Sciences of the United States of America.2013 Apr 23;6712-723569284
Bioreactor engineering of stem cell environments.Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, GordanaBiotechnology advances2013 Mar 2423531529
Poly(?-caprolactone)-carbon nanotube composite scaffolds for enhanced cardiac differentiation of human mesenchymal stem cells.Crowder, Spencer W; Liang, Yi; Rath, Rutwik; Park, Andrew M; Maltais, Simon; Pintauro, Peter N; Hofmeister, William; Lim, Chee C; Wang, Xintong; Sung, Hak-JoonNanomedicine (London, England).2013 Nov;1763-7623530764
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury.Kida, Yujiro; Ieronimakis, Nicholas; Schrimpf, Claudia; Reyes, Morayma; Duffield, Jeremy SJournal of the American Society of Nephrology : JASN.2013 Mar;559-7223492730
A new dynamic in vitro modular capillaries-venules modular system: cerebrovascular physiology in a box.Cucullo, Luca; Hossain, Mohammed; Tierney, William; Janigro, DamirBMC neuroscience.2013;1823388041
Standardizing data.Baker, Nathan A; Klemm, Juli D; Harper, Stacey L; Gaheen, Sharon; Heiskanen, Mervi; Rocca-Serra, Philippe; Sansone, Susanna-AssuntaNature nanotechnology2013 Feb73-423380926
Engineering challenges for instrumenting and controlling integrated organ-on-chip systems.Wikswo, John P; Block 3rd, Frank E; Cliffel, David E; Goodwin, Cody R; Marasco, Christina C; Markov, Dmitry A; McLean, David L; McLean, John A; McKenzie, Jennifer R; Reiserer, Ronald S; Samson, Philip C; Schaffer, David K; Seale, Kevin T; Sherrod, Stacy DIEEE transactions on bio-medical engineering2013 Mar682-9023380852
Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes.Robertson, Claire; Tran, David D; George, Steven CStem cells (Dayton, Ohio).2013 May;829-3723355363
Nonsteady state oxygen transport in engineered tissue: implications for design.Ehsan, Seema M; George, Steven CTissue engineering. Part A.2013 Jun;1433-4223350630
Multifunctionality and control of the crumpling and unfolding of large-area graphene.Zang, Jianfeng; Ryu, Seunghwa; Pugno, Nicola; Wang, Qiming; Tu, Qing; Buehler, Markus J; Zhao, XuanheNature materials.2013 Apr;321-523334002
Modeling boundary conditions for balanced proliferation in metastatic latency.Taylor, Donald P; Wells, Jakob Z; Savol, Andrej; Chennubhotla, Chakra; Wells, AlanClinical cancer research : an official journal of the American Association for Cancer Research2013 Mar 11063-7023329811
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis.Campanholle, Gabriela; Ligresti, Giovanni; Gharib, Sina A; Duffield, Jeremy SAmerican journal of physiology. Cell physiology.2013 Apr 1;C591-60323325411
ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format.Thomas, Dennis G; Gaheen, Sharon; Harper, Stacey L; Fritts, Martin; Klaessig, Fred; Hahn-Dantona, Elizabeth; Paik, David; Pan, Sue; Stafford, Grace A; Freund, Elaine T; Klemm, Juli D; Baker, Nathan ABMC biotechnology2013223311978
The inexorable rise of AKI: can we bend the growth curve?Siew, Edward D; Himmelfarb, JonathanJournal of the American Society of Nephrology : JASN.2013 Jan;5-Mar23243210
Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells.Cimetta, Elisa; Sirabella, Dario; Yeager, Keith; Davidson, Kathryn; Simon, Joseph; Moon, Randall T; Vunjak-Novakovic, GordanaLab on a chip2013 Feb 7355-6423232509
A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.Huh, Dongeun; Leslie, Daniel C; Matthews, Benjamin D; Fraser, Jacob P; Jurek, Samuel; Hamilton, Geraldine A; Thorneloe, Kevin S; McAlexander, Michael Allen; Ingber, Donald EScience translational medicine2012 Nov 7159ra14723136042
Elucidation of adhesion-dependent spontaneous apoptosis in macrophages using phase separated PEG/polyurethane films.Zachman, Angela L; Page, Jonathan M; Prabhakar, Gayathri; Guelcher, Scott A; Sung, Hak-JoonActa biomaterialia.2013 Feb;4964-7523128157
Angiogenesis is required for stress fracture healing in rats.Tomlinson, Ryan E; McKenzie, Jennifer A; Schmieder, Anne H; Wohl, Gregory R; Lanza, Gregory M; Silva, Matthew JBone2013 Jan212-923044046
Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide.Zhang, Lingbo; Wang, Kezheng; Zhao, Falin; Hu, Weiping; Chen, Junjie; Lanza, Gregory M; Shen, Baozhong; Zhang, BinPloS one2012e4625523029451
Nanoinformatics: developing new computing applications for nanomedicine.Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; GranComputing in science & engineering2012 Jun 1521-53922942787
Nanoinformatics: developing new computing applications for nanomedicine.Maojo, V; Fritts, M; Martin-Sanchez, F; De la Iglesia, D; Cachau, R E; Garcia-Remesal, M; Crespo, J; Mitchell, J A; Anguita, A; Baker, N; Barreiro, J M; Benitez, S E; De la Calle, G; Facelli, J C; Ghazal, P; Geissbuhler, A; Gonzalez-Nilo, F; Graf, N; Grangeat, P; Hermosilla, I; Hussein, R; Kern, J; Koch, S; Legre, Y; Lopez-Alonso, V; Lopez-Campos, G; Milanesi, L; Moustakis, V; Munteanu, C; Otero, P; Pazos, A; Perez-Rey, D; Potamias, G; Sanz, F; Kulikowski, CComputing in science & engineering2012 Jun 1521-53922942787
Suppression of inflammation in a mouse model of rheumatoid arthritis using targeted lipase-labile fumagillin prodrug nanoparticles.Zhou, Hui-Fang; Yan, Huimin; Senpan, Angana; Wickline, Samuel A; Pan, Dipanjan; Lanza, Gregory M; Pham, Christine T NBiomaterials2012 Nov8632-4022922023
Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence.Hu, Lingzhi; Chen, Junjie; Yang, Xiaoxia; Caruthers, Shelton D; Lanza, Gregory M; Wickline, Samuel AMagnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine2012 Aug 2222915328
A mini-microscope for in situ monitoring of cells.Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, AliLab on a chip2012 Oct 213976-8222911426
The contribution of cellular mechanotransduction to cardiomyocyte form and function.Sheehy, Sean P; Grosberg, Anna; Parker, Kevin KitBiomechanics and modeling in mechanobiology2012 Nov1227-3922772714
Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers.Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan ASoft matter2012 Jan 13024-303522712024
Antiangiogenic nanotherapy with lipase-labile Sn-2 fumagillin prodrug.Pan, Dipanjan; Sanyal, Nibedita; Schmieder, Anne H; Senpan, Angana; Kim, Benjamin; Yang, Xiaoxia; Hu, Grace; Allen, John S; Gross, Richard W; Wickline, Samuel A; Lanza, Gregory MNanomedicine (London, England)2012 Oct1507-1922709347
Adaptive clinical trials: a partial remedy for the therapeutic misconception?Meurer, William J; Lewis, Roger J; Berry, Donald AJAMA : the journal of the American Medical Association2012 Jun 132377-822692168
Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier.Janigro, DamirEpilepsia.2012 Jun;26-3422612806
Effect of insurance status on postacute care among working age stroke survivors.Skolarus, L E; Meurer, W J; Burke, J F; Prvu Bettger, J; Lisabeth, L DNeurology2012 May 151590-522551730
Muscle on a chip: in vitro contractility assays for smooth and striated muscle.Grosberg, Anna; Nesmith, Alexander P; Goss, Josue A; Brigham, Mark D; McCain, Megan L; Parker, Kevin KitJournal of pharmacological and toxicological methods2012 May-Jun126-3522521339
ICAM-1 and nanomedicine: nature's doorway to the extravascular tissue realm.Lanza, Gregory MArteriosclerosis, thrombosis, and vascular biology2012 May1070-122517363
An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project.Meurer, William J; Lewis, Roger J; Tagle, Danilo; Fetters, Michael D; Legocki, Laurie; Berry, Scott; Connor, Jason; Durkalski, Valerie; Elm, Jordan; Zhao, Wenle; Frederiksen, Shirley; Silbergleit, Robert; Palesch, Yuko; Berry, Donald A; Barsan, William GAnnals of emergency medicine2012 Oct451-722424650
An early investigation of ytterbium nanocolloids for selective and quantitative "multicolor" spectral CT imaging.Pan, Dipanjan; Schirra, Carsten O; Senpan, Angana; Schmieder, Anne H; Stacy, Allen J; Roessl, Ewald; Thran, Axel; Wickline, Samuel A; Proska, Roland; Lanza, Gregory MACS nano2012 Apr 243364-7022385324
Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip.Grosberg, Anna; Alford, Patrick W; McCain, Megan L; Parker, Kevin KitLab on a chip2011 Dec 214165-7322072288
Interaction of melittin peptides with perfluorocarbon nanoemulsion particles.Lee, Sun-Joo; Schlesinger, Paul H; Wickline, Samuel A; Lanza, Gregory M; Baker, Nathan AThe journal of physical chemistry. B2011 Dec 2915271-922050303
Nanotherapeutic approaches for the treatment of rheumatoid arthritis.Pham, Christine T NWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.2011 Nov-Dec;607-1921837725
Informatics and standards for nanomedicine technology.Thomas, Dennis G; Klaessig, Fred; Harper, Stacey L; Fritts, Martin; Hoover, Mark D; Gaheen, Sharon; Stokes, Todd H; Reznik-Zellen, Rebecca; Freund, Elaine T; Klemm, Juli D; Paik, David S; Baker, Nathan AWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2011 Jun 30NULL21721140
Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces.Pham, Christine T N; Mitchell, Lynne M; Huang, Jennifer L; Lubniewski, Christopher M; Schall, Otto F; Killgore, J Kendall; Pan, Dipanjan; Wickline, Samuel A; Lanza, Gregory M; Hourcade, Dennis EThe Journal of biological chemistry2011 Jan 7123-3021047788
Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of *-catenin signaling.Cimetta, Elisa; Cannizzaro, Christopher; James, Richard; Biechele, Travis; Moon, Randall T; Elvassore, Nicola; Vunjak-Novakovic, GordanaLab on a chip.2010 Dec 7;3277-8320936235


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