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NIH Director's Early Independence Award Program (343)
Publication TitleAuthorsJournalPublication DatePage NoPubMedID
Toward understanding thalamocortical dysfunction in schizophrenia through computational models of neural circuit dynamics.Murray, John D; Anticevic, AlanSchizophrenia research.2016 Oct 23;27784534
Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency.Southard, Sheryl; Kim, Ju-Ryoung; Low, SiewHui; Tsika, Richard W; Lepper, ChristopheLife.2016 Oct 11;27725085
Predicting the Future - Big Data, Machine Learning, and Clinical Medicine.Obermeyer, Ziad; Emanuel, Ezekiel JThe New England journal of medicine.2016 Sep 29;27682033
Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins.Sun, Zhen-Yu J; Bhanu, Meera K; Allan, Martin G; Arthanari, Haribabu; Wagner, Gerhard; Hanna, JohnPloS one.2016;27662200
Astrocyte-produced leukemia inhibitory factor expands the neural stem/progenitor pool following perinatal hypoxia-ischemia.Felling, Ryan J; Covey, Matthew V; Wolujewicz, Paul; Batish, Mona; Levison, Steven WJournal of neuroscience research.2016 Dec;27661001
Convex Regression with Interpretable Sharp Partitions.Petersen, Ashley; Simon, Noah; Witten, DanielaJournal of machine learning research : JMLR.2016 Jun;27635120
Selection and estimation for mixed graphical models.Chen, Shizhe; Witten, Daniela M; Shojaie, AliBiometrika.2015 Mar;27625437
Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.Pascolutti, Roberta; Sun, Xianqiang; Kao, Joseph; Maute, Roy L; Ring, Aaron M; Bowman, Gregory R; Kruse, Andrew CStructure (London, England : 1993).2016 Oct 4;27618663
Statistical properties of convex clustering.Tan, Kean Ming; Witten, DanielaElectronic journal of statistics.2015;27617051
Applications of CRISPR Genome Engineering in Cell Biology.Wang, Fangyuan; Qi, Lei STrends in cell biology.2016 Sep 3;27599850
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.Sidik, Saima M; Huet, Diego; Ganesan, Suresh M; Huynh, My-Hang; Wang, Tim; Nasamu, Armiyaw S; Thiru, Prathapan; Saeij, Jeroen P J; Carruthers, Vern B; Niles, Jacquin C; Lourido, SebastianCell.2016 Sep 8;27594426
Longitudinal social networks impacts on weight and weight-related behaviors assessed using mobile-based ecological momentary assessments: Study Protocols for the SPARC study.Bruening, Meg; Ohri-Vachaspati, Punam; Brewis, Alexandra; Laska, Melissa; Todd, Michael; Hruschka, Daniel; Schaefer, David R; Whisner, Corrie M; Dunton, GenevieveBMC public health.2016 Aug 30;27576358
Size doesn't matter in the heat shock response.Pincus, DavidCurrent genetics.2016 Aug 8;27502399
Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.Tycko, Josh; Myer, Vic E; Hsu, Patrick DMolecular cell.2016 Aug 4;27494557
Optimally controlling the human connectome: the role of network topology.Betzel, Richard F; Gu, Shi; Medaglia, John D; Pasqualetti, Fabio; Bassett, Danielle SScientific reports.2016 Jul 29;27468904
Immunogenicity of a Meningococcal B Vaccine during a University Outbreak.Basta, Nicole E; Mahmoud, Adel A F; Wolfson, Julian; Ploss, Alexander; Heller, Brigitte L; Hanna, Sarah; Johnsen, Peter; Izzo, Robin; Grenfell, Bryan T; Findlow, Jamie; Bai, Xilian; Borrow, RayThe New England journal of medicine.2016 Jul 21;27468058
A Mobile Ecological Momentary Assessment Tool (devilSPARC) for Nutrition and Physical Activity Behaviors in College Students: A Validation Study.Bruening, Meg; van Woerden, Irene; Todd, Michael; Brennhofer, Stephanie; Laska, Melissa N; Dunton, GenevieveJournal of medical Internet research.2016 Jul 27;27465701
Immune DNA signature of T-cell infiltration in breast tumor exomes.Levy, Eric; Marty, Rachel; Gárate Calderón, Valentina; Woo, Brian; Dow, Michelle; Armisen, Ricardo; Carter, Hannah; Harismendy, OlivierScientific reports.2016 Jul 25;27452728
JNK pathway activation modulates acquired resistance to EGFR/HER2 targeted therapies.Manole, Simin; Richards, Edward J; Meyer, Aaron SCancer research.2016 Jul 22;27450453
Recent applications of phthalocyanines and naphthalocyanines for imaging and therapy.Zhang, Yumiao; Lovell, Jonathan FWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.2016 Jul 20;27439671
ADDENDUM: T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells.Zah, Eugenia; Lin, Meng-Yin; Silva-Benedict, Anne; Jensen, Michael C; Chen, Yvonne YCancer immunology research.2016 Jul;27371639
Y-Chromosome Structural Diversity in the Bonobo and Chimpanzee Lineages.Oetjens, Matthew T; Shen, Feichen; Emery, Sarah B; Zou, Zhengting; Kidd, Jeffrey MGenome biology and evolution.2016;27358426
Burden of emergency conditions and emergency care usage: new estimates from 40 countries.Chang, Cindy Y; Abujaber, Samer; Reynolds, Teri A; Camargo Jr, Carlos A; Obermeyer, ZiadEmergency medicine journal : EMJ.2016 Jun 22;27334758
A Systematic Review of Methods and Procedures Used in Ecological Momentary Assessments of Diet and Physical Activity Research in Youth: An Adapted STROBE Checklist for ReportinLiao, Yue; Skelton, Kara; Dunton, Genevieve; Bruening, MegJournal of medical Internet research.2016;27328833
Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.Solís, Eric J; Pandey, Jai P; Zheng, Xu; Jin, Dexter X; Gupta, Piyush B; Airoldi, Edoardo M; Pincus, David; Denic, VladimirMolecular cell.2016 Jul 7;27320198
Emerging roles for antigen presentation in establishing host-microbiome symbiosis.Bessman, Nicholas J; Sonnenberg, Gregory FImmunological reviews.2016 Jul;27319348
Hospital Prescribing of Opioids to Medicare Beneficiaries.Jena, Anupam B; Goldman, Dana; Karaca-Mandic, PinarJAMA internal medicine.2016 Jul 1;27294595
Resolving complex structural genomic rearrangements using a randomized approach.Zhao, Xuefang; Emery, Sarah B; Myers, Bridget; Kidd, Jeffrey M; Mills, Ryan EGenome biology.2016 Jun 10;27287201
Directed vaccination against pneumococcal disease.Li, Yi; Hill, Andrew; Beitelshees, Marie; Shao, Shuai; Lovell, Jonathan F; Davidson, Bruce A; Knight 3rd, Paul R; Hakansson, Anders P; Pfeifer, Blaine A; Jones, Charles HProceedings of the National Academy of Sciences of the United States of America.2016 Jun 21;27274071
Popular Music Celebrity Endorsements in Food and Nonalcoholic Beverage Marketing.Bragg, Marie A; Miller, Alysa N; Elizee, Juleen; Dighe, Shatabdi; Elbel, Brian DPediatrics.2016 Jul;27273712
Differences in incomes of physicians in the United States by race and sex: observational study.Ly, Dan P; Seabury, Seth A; Jena, Anupam BBMJ (Clinical research ed.).2016;27268490
High-resolution contrast-enhanced optical coherence tomography in mice retinae.Sen, Debasish; SoRelle, Elliott D; Liba, Orly; Dalal, Roopa; Paulus, Yannis M; Kim, Tae-Wan; Moshfeghi, Darius M; de la Zerda, AdamJournal of biomedical optics.2016 Jun 1;27264492
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.Peters, Jason M; Colavin, Alexandre; Shi, Handuo; Czarny, Tomasz L; Larson, Matthew H; Wong, Spencer; Hawkins, John S; Lu, Candy H S; Koo, Byoung-Mo; Marta, Elizabeth; Shiver, Anthony L; Whitehead, Evan H; Weissman, Jonathan S; Brown, Eric D; Qi, Lei S; Huang, Kerwyn Casey; Gross, Carol ACell.2016 Jun 2;27238023
Coherent-weighted three-dimensional image reconstruction in linear-array-based photoacoustic tomography.Wang, Depeng; Wang, Yuehang; Zhou, Yang; Lovell, Jonathan F; Xia, JunBiomedical optics express.2016 May 1;27231634
Tmc1 Is a Dynamically Regulated Effector of the Rpn4 Proteotoxic Stress Response.Guerra-Moreno, Angel; Hanna, JohnThe Journal of biological chemistry.2016 Jul 8;27226598
Factors Related to the High Rates of Food Insecurity among Diverse, Urban College Freshmen.Bruening, Meg; Brennhofer, Stephanie; van Woerden, Irene; Todd, Michael; Laska, MelissaJournal of the Academy of Nutrition and Dietetics.2016 May 17;27212147
Prediction Policy Problems.Kleinberg, Jon; Ludwig, Jens; Mullainathan, Sendhil; Obermeyer, ZiadThe American economic review.2015 May;27199498
Utilization of Telemedicine Among Rural Medicare Beneficiaries.Mehrotra, Ateev; Jena, Anupam B; Busch, Alisa B; Souza, Jeffrey; Uscher-Pines, Lori; Landon, Bruce EJAMA.2016 May 10;27163991
IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.Ferris, Sean P; Goode, Benjamin; Joseph, Nancy M; Kline, Cassie N; Samuel, David; Gupta, Nalin; Bollen, Andrew; Perry, Arie; Mueller, Sabine; Solomon, David AActa neuropathologica.2016 Jul;27161253
Low Dimensionality in Gene Expression Data Enables the Accurate Extraction of Transcriptional Programs from Shallow Sequencing.Heimberg, Graham; Bhatnagar, Rajat; El-Samad, Hana; Thomson, MattCell systems.2016 Apr 27;27135536
Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin-Phospholipids.Luo, Dandan; Li, Nasi; Carter, Kevin A; Lin, Cuiyan; Geng, Jumin; Shao, Shuai; Huang, Wei-Chiao; Qin, Yueling; Atilla-Gokcumen, G Ekin; Lovell, Jonathan FSmall (Weinheim an der Bergstrasse, Germany).2016 Jun;27121003
Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.Hill, Alison L; Rosenbloom, Daniel I S; Goldstein, Edward; Hanhauser, Emily; Kuritzkes, Daniel R; Siliciano, Robert F; Henrich, Timothy JPLoS pathogens.2016 Apr;27119536
Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting.Mavor, David; Barlow, Kyle; Thompson, Samuel; Barad, Benjamin A; Bonny, Alain R; Cario, Clinton L; Gaskins, Garrett; Liu, Zairan; Deming, Laura; Axen, Seth D; Caceres, Elena; Chen, Weilin; Cuesta, Adolfo; Gate, Rachel E; Green, Evan M; Hulce, Kaitlin R; JeLife.2016 Apr 25;27111525
The Role of Genome Accessibility in Transcription Factor Binding in Bacteria.Gomes, Antonio L C; Wang, Harris HPLoS computational biology.2016 Apr;27104615
Principles for designing synthetic microbial communities.Johns, Nathan I; Blazejewski, Tomasz; Gomes, Antonio Lc; Wang, Harris HCurrent opinion in microbiology.2016 Jun;27084981
Short-term Outcomes for Medicare Beneficiaries After Low-acuity Visits to Emergency Departments and Clinics.Niedzwiecki, Matthew; Baicker, Katherine; Wilson, Michael; Cutler, David M; Obermeyer, ZiadMedical care.2016 May;27078822
The diversity-generating benefits of a prokaryotic adaptive immune system.van Houte, Stineke; Ekroth, Alice K E; Broniewski, Jenny M; Chabas, Hélène; Ashby, Ben; Bondy-Denomy, Joseph; Gandon, Sylvain; Boots, Mike; Paterson, Steve; Buckling, Angus; Westra, Edze RNature.2016 Apr 21;27074511
T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells.Zah, Eugenia; Lin, Meng-Yin; Silva-Benedict, Anne; Jensen, Michael C; Chen, Yvonne YCancer immunology research.2016 Jun;27059623
Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.Engin, H Billur; Kreisberg, Jason F; Carter, HannahPloS one.2016;27043210
Measuring and modeling diffuse scattering in protein X-ray crystallography.Van Benschoten, Andrew H; Liu, Lin; Gonzalez, Ana; Brewster, Aaron S; Sauter, Nicholas K; Fraser, James S; Wall, Michael EProceedings of the National Academy of Sciences of the United States of America.2016 Apr 12;27035972
Amygdala volume is reduced in early course schizophrenia.Rich, Alyson M; Cho, Youngsun T; Tang, Yanqing; Savic, Aleksandar; Krystal, John H; Wang, Fei; Xu, Ke; Anticevic, AlanPsychiatry research.2016 Apr 30;27035063
A Phosphorus Phthalocyanine Formulation with Intense Absorbance at 1000 nm for Deep Optical Imaging.Zhou, Yang; Wang, Depeng; Zhang, Yumiao; Chitgupi, Upendra; Geng, Jumin; Wang, Yuehang; Zhang, Yuzhen; Cook, Timothy R; Xia, Jun; Lovell, Jonathan FTheranostics.2016;27022416
HPV vaccine uptake among overweight and obese US adolescents: An analysis of the National Health and Nutrition Examination Survey (NHANES) 2009-2014.Sundaram, Maria E; Mason, Susan M; Basta, Nicole EVaccine.2016 May 11;27020709
Discovery of unfixed endogenous retrovirus insertions in diverse human populations.Wildschutte, Julia Halo; Williams, Zachary H; Montesion, Meagan; Subramanian, Ravi P; Kidd, Jeffrey M; Coffin, John MProceedings of the National Academy of Sciences of the United States of America.2016 Apr 19;27001843
Reducing prognostic errors: a new imperative in quality healthcare.Khullar, Dhruv; Jena, Anupam BBMJ (Clinical research ed.).2016;26993146
Screening Mammography for Free: Impact of Eliminating Cost Sharing on Cancer Screening Rates.Jena, Anupam B; Huang, Jie; Fireman, Bruce; Fung, Vicki; Gazelle, Scott; Landrum, Mary Beth; Chernew, Michael; Newhouse, Joseph P; Hsu, JohnHealth services research.2016 Mar 17;26990550
Contrast-enhanced optical coherence tomography with picomolar sensitivity for functional in vivo imaging.Liba, Orly; SoRelle, Elliott D; Sen, Debasish; de la Zerda, AdamScientific reports.2016;26987475
Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism.Fung, Thomas C; Bessman, Nicholas J; Hepworth, Matthew R; Kumar, Nitin; Shibata, Naoko; Kobuley, Dmytro; Wang, Kelvin; Ziegler, Carly G K; Goc, Jeremy; Shima, Tatsuichiro; Umesaki, Yoshinori; Sartor, R Balfour; Sullivan, Kaede V; Lawley, Trevor D; Kunisawa, Jun; Kiyono, Hiroshi; Sonnenberg, Gregory FImmunity.2016 Mar 15;26982365
Regression discontinuity designs in healthcare research.Venkataramani, Atheendar S; Bor, Jacob; Jena, Anupam BBMJ (Clinical research ed.).2016;26977086
Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL).Kasar, Siddha; Underbayev, Chingiz; Hassan, Moinuddin; Ilev, Ilko; Degheidy, Heba; Bauer, Steven; Marti, Gerald; Lutz, Carol; Raveche, Elizabeth; Batish, MonaPloS one.2016;26959643
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells.Myers, Samuel A; Peddada, Sailaja; Chatterjee, Nilanjana; Friedrich, Tara; Tomoda, Kiichrio; Krings, Gregor; Thomas, Sean; Maynard, Jason; Broeker, Michael; Thomson, Matthew; Pollard, Katherine; Yamanaka, Shinya; Burlingame, Alma L; Panning, BarbaraeLife.2016;26949256
Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.Sidik, Saima M; Hortua Triana, Miryam A; Paul, Aditya S; El Bakkouri, Majida; Hackett, Caroline G; Tran, Fanny; Westwood, Nicholas J; Hui, Raymond; Zuercher, William J; Duraisingh, Manoj T; Moreno, Silvia N J; Lourido, SebastianThe Journal of biological chemistry.2016 Apr 29;26933036
Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis.Demehri, Shadmehr; Cunningham, Trevor J; Manivasagam, Sindhu; Ngo, Kenneth H; Moradi Tuchayi, Sara; Reddy, Rasika; Meyers, Melissa A; DeNardo, David G; Yokoyama, Wayne MThe Journal of clinical investigation.2016 Apr 1;26927668
The Emergency Care of Patients With Cancer: Setting the Research Agenda.Brown, Jeremy; Grudzen, Corita; Kyriacou, Demetrios N; Obermeyer, Ziad; Quest, Tammie; Rivera, Donna; Stone, Susan; Wright, Jason; Shelburne, NonniekayeAnnals of emergency medicine.2016 Feb 26;26921969
Manipulating Bacterial Communities by in situ Microbiome Engineering.Sheth, Ravi U; Cabral, Vitor; Chen, Sway P; Wang, Harris HTrends in genetics : TIG.2016 Apr;26916078
Visualizing antibody affinity maturation in germinal centers.Tas, Jeroen M J; Mesin, Luka; Pasqual, Giulia; Targ, Sasha; Jacobsen, Johanne T; Mano, Yasuko M; Chen, Casie S; Weill, Jean-Claude; Reynaud, Claude-Agnès; Browne, Edward P; Meyer-Hermann, Michael; Victora, Gabriel DScience (New York, N.Y.).2016 Mar 4;1048-5426912368
Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study.Aguirre-Acevedo, Daniel C; Lopera, Francisco; Henao, Eliana; Tirado, Victoria; Muñoz, Claudia; Giraldo, Margarita; Bangdiwala, Shrikant I; Reiman, Eric M; Tariot, Pierre N; Langbaum, Jessica B; Quiroz, Yakeel T; Jaimes, FabianJAMA neurology.2016 Apr;26902171
MEKK2 mediates an alternative ?-catenin pathway that promotes bone formation.Greenblatt, Matthew Blake; Shin, Dong Yeon; Oh, Hwanhee; Lee, Ki-Young; Zhai, Bo; Gygi, Steven P; Lotinun, Sutada; Baron, Roland; Liu, Dou; Su, Bing; Glimcher, Laurie H; Shim, Jae-HyuckProceedings of the National Academy of Sciences of the United States of America.2016 Mar 1;26884171
Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells.Ede, Christopher; Chen, Ximin; Lin, Meng-Yin; Chen, Yvonne YACS synthetic biology.2016 May 20;26883397
Transient inhibition of ROR-?t therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells.Withers, David R; Hepworth, Matthew R; Wang, Xinxin; Mackley, Emma C; Halford, Emily E; Dutton, Emma E; Marriott, Clare L; Brucklacher-Waldert, Verena; Veldhoen, Marc; Kelsen, Judith; Baldassano, Robert N; Sonnenberg, Gregory FNature medicine.2016 Mar;26878233
Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation.Weinberg, David E; Shah, Premal; Eichhorn, Stephen W; Hussmann, Jeffrey A; Plotkin, Joshua B; Bartel, David PCell reports.2016 Feb 23;1787-9926876183
Quantitative contrast-enhanced optical coherence tomography.Winetraub, Yonatan; SoRelle, Elliott D; Liba, Orly; de la Zerda, AdamApplied physics letters.2016 Jan 11;26869724
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans.Amrit, Francis Raj Gandhi; Steenkiste, Elizabeth Marie; Ratnappan, Ramesh; Chen, Shaw-Wen; McClendon, T Brooke; Kostka, Dennis; Yanowitz, Judith; Olsen, Carissa Perez; Ghazi, ArjumandPLoS genetics.2016 Feb;26862916
CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.Cimermancic, Peter; Weinkam, Patrick; Rettenmaier, T Justin; Bichmann, Leon; Keedy, Daniel A; Woldeyes, Rahel A; Schneidman-Duhovny, Dina; Demerdash, Omar N; Mitchell, Julie C; Wells, James A; Fraser, James S; Sali, AndrejJournal of molecular biology.2016 Feb 22;26854760
Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.Morsut, Leonardo; Roybal, Kole T; Xiong, Xin; Gordley, Russell M; Coyle, Scott M; Thomson, Matthew; Lim, Wendell ACell.2016 Feb 11;780-9126830878
Emergency Care Use and the Medicare Hospice Benefit for Individuals with Cancer with a Poor Prognosis.Obermeyer, Ziad; Clarke, Alissa C; Makar, Maggie; Schuur, Jeremiah D; Cutler, David MJournal of the American Geriatrics Society.2016 Feb;26805592
CD8+ T cells mediate antibody-independent platelet clearance in mice.Arthur, Connie M; Patel, Seema R; Sullivan, H Cliff; Winkler, Annie M; Tormey, Chris A; Hendrickson, Jeanne E; Stowell, Sean RBlood.2016 Apr 7;26787734
An Introduction to CRISPR Technology for Genome Activation and Repression in Mammalian Cells.Du, Dan; Qi, Lei SCold Spring Harbor protocols.2016 Jan;26729914
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.Henn, Brenna M; Botigué, Laura R; Peischl, Stephan; Dupanloup, Isabelle; Lipatov, Mikhail; Maples, Brian K; Martin, Alicia R; Musharoff, Shaila; Cann, Howard; Snyder, Michael P; Excoffier, Laurent; Kidd, Jeffrey M; Bustamante, Carlos DProceedings of the National Academy of Sciences of the United States of America.2016 Jan 26;E440-926712023
Slit-enabled linear-array photoacoustic tomography with near isotropic spatial resolution in three dimensions.Wang, Yuehang; Wang, Depeng; Zhang, Yumiao; Geng, Jumin; Lovell, Jonathan F; Xia, JunOptics letters.2016 Jan 1;26696175
Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation.Dominguez, Antonia A; Lim, Wendell A; Qi, Lei SNature reviews. Molecular cell biology.2016 Jan;26670017
Do heads of government age more quickly? Observational study comparing mortality between elected leaders and runners-up in national elections of 17 countries.Olenski, Andrew R; Abola, Matthew V; Jena, Anupam BBMJ (Clinical research ed.).2015;26666894
Association between use of warfarin with common sulfonylureas and serious hypoglycemic events: retrospective cohort analysis.Romley, John A; Gong, Cynthia; Jena, Anupam B; Goldman, Dana P; Williams, Bradley; Peters, AnneBMJ (Clinical research ed.).2015;h622326643108
Reversible Micro- and Nano- Phase Programming of Anthraquinone Thermochromism Using Blended Block Copolymers.Zhang, Yumiao; Lovell, Jonathan FLangmuir : the ACS journal of surfaces and colloids.2015 Dec 22;26626998
Identification of Direct Kinase Substrates Using Analogue-Sensitive Alleles.Rothenberg, Daniel A; Gordon, Elizabeth A; White, Forest M; Lourido, SebastianMethods in molecular biology (Clifton, N.J.).2016;26584919
High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction.Thomaston, Jessica L; Alfonso-Prieto, Mercedes; Woldeyes, Rahel A; Fraser, James S; Klein, Michael L; Fiorin, Giacomo; DeGrado, William FProceedings of the National Academy of Sciences of the United States of America.2015 Nov 17;14260-526578770
Porphyrin-phospholipid liposomes with tunable leakiness.Luo, Dandan; Carter, Kevin A; Razi, Aida; Geng, Jumin; Shao, Shuai; Lin, Cuiyan; Ortega, Joaquin; Lovell, Jonathan FJournal of controlled release : official journal of the Controlled Release Society.2015 Dec 28;484-9426578438
Innate immunity against molecular mimicry: Examining galectin-mediated antimicrobial activity.Arthur, Connie M; Patel, Seema R; Mener, Amanda; Kamili, Nourine A; Fasano, Ross M; Meyer, Erin; Winkler, Annie M; Sola-Visner, Martha; Josephson, Cassandra D; Stowell, Sean RBioEssays : news and reviews in molecular, cellular and developmental biology.2015 Dec;1327-3726577077
Higher Tetanus Toxoid Immunity 2 Years After PsA-TT Introduction in Mali.Basta, Nicole E; Borrow, Ray; Berthe, Abdoulaye; Onwuchekwa, Uma; Dembélé, Awa Traoré Eps; Almond, Rachael; Frankland, Sarah; Patel, Sima; Wood, Daniel; Nascimento, Maria; Manigart, Olivier; Trotter, Caroline L; Greenwood, Brian; Sow, Samba OClinical infectious diseases : an official publication of the Infectious Diseases Society of America.2015 Nov 15;S578-8526553691
Population-Level Persistence of Immunity 2 Years After the PsA-TT Mass-Vaccination Campaign in Mali.Basta, Nicole E; Borrow, Ray; Berthe, Abdoulaye; Dembélé, Awa Traoré Eps; Onwuchekwa, Uma; Townsend, Kelly; Boukary, Rahamatou M; Mabey, Lesley; Findlow, Helen; Bai, Xilian; Sow, Samba OClinical infectious diseases : an official publication of the Infectious Diseases Society of America.2015 Nov 15;S547-5326553687
Physician spending and subsequent risk of malpractice claims: observational study.Jena, Anupam B; Schoemaker, Lena; Bhattacharya, Jay; Seabury, Seth ABMJ (Clinical research ed.).2015;h551626538498
2D cine DENSE with low encoding frequencies accurately quantifies cardiac mechanics with improved image characteristics.Wehner, Gregory J; Grabau, Jonathan D; Suever, Jonathan D; Haggerty, Christopher M; Jing, Linyuan; Powell, David K; Hamlet, Sean M; Vandsburger, Moriel H; Zhong, Xiaodong; Fornwalt, Brandon KJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.2015;26538111
13C- and 15N-Labeling Strategies Combined with Mass Spectrometry Comprehensively Quantify Phospholipid Dynamics in C. elegans.Dancy, Blair C R; Chen, Shaw-Wen; Drechsler, Robin; Gafken, Philip R; Olsen, Carissa PerezPloS one.2015;e014185026528916
Gadolinium free cardiovascular magnetic resonance with 2-point Cine balanced steady state free precession.Stromp, Tori A; Leung, Steve W; Andres, Kristin N; Jing, Linyuan; Fornwalt, Brandon K; Charnigo, Richard J; Sorrell, Vincent L; Vandsburger, Moriel HJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.2015;26520782
A porphyrin-PEG polymer with rapid renal clearance.Huang, Haoyuan; Hernandez, Reinier; Geng, Jumin; Sun, Haotian; Song, Wentao; Chen, Feng; Graves, Stephen A; Nickles, Robert J; Cheng, Chong; Cai, Weibo; Lovell, Jonathan FBiomaterials.2016 Jan;25-3226517562
Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release.Luo, Dandan; Carter, Kevin A; Razi, Aida; Geng, Jumin; Shao, Shuai; Giraldo, Daniel; Sunar, Ulas; Ortega, Joaquin; Lovell, Jonathan FBiomaterials.2016 Jan;193-20226513413
Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit.Keedy, Daniel A; Fraser, James S; van den Bedem, HenryPLoS computational biology.2015 Oct;e100450726506617
Discovery and characterization of Alu repeat sequences via precise local read assembly.Wildschutte, Julia H; Baron, Alayna; Diroff, Nicolette M; Kidd, Jeffrey MNucleic acids research.2015 Dec 2;26503250
Germinal center selection and the antibody response to influenza.Victora, Gabriel D; Wilson, Patrick CCell.2015 Oct 22;545-826496601
Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response.Guerra-Moreno, Angel; Isasa, Marta; Bhanu, Meera K; Waterman, David P; Eapen, Vinay V; Gygi, Steven P; Hanna, JohnThe Journal of biological chemistry.2015 Dec 11;29695-70626491016
Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1.Rosenbloom, Daniel I S; Elliott, Oliver; Hill, Alison L; Henrich, Timothy J; Siliciano, Janet M; Siliciano, Robert FOpen forum infectious diseases.2015 Dec;26478893
Emergency care in 59 low- and middle-income countries: a systematic review.Obermeyer, Ziad; Abujaber, Samer; Makar, Maggie; Stoll, Samantha; Kayden, Stephanie R; Wallis, Lee A; Reynolds, Teri A; Acute Care Development ConsortiumBulletin of the World Health Organization.2015 Aug 1;577-586G26478615
Biofunctionalization of Large Gold Nanorods Realizes Ultrahigh-Sensitivity Optical Imaging Agents.SoRelle, Elliott D; Liba, Orly; Hussain, Zeshan; Gambhir, Milan; de la Zerda, AdamLangmuir : the ACS journal of surfaces and colloids.2015 Nov 17;26477361
Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice.Hao, Shuang; Tang, Bin; Wu, Zhenyu; Ure, Kerstin; Sun, Yaling; Tao, Huifang; Gao, Yan; Patel, Akash J; Curry, Daniel J; Samaco, Rodney C; Zoghbi, Huda Y; Tang, JianrongNature.2015 Oct 15;430-426469053
Outcomes of Basic Versus Advanced Life Support for Out-of-Hospital Medical Emergencies.Sanghavi, Prachi; Jena, Anupam B; Newhouse, Joseph P; Zaslavsky, Alan MAnnals of internal medicine.2015 Nov 3;681-9026457627
Group 3 innate lymphoid cells: regulating host-commensal bacteria interactions in inflammation and cancer.Goc, Jeremy; Hepworth, Matthew R; Sonnenberg, Gregory FInternational immunology.2016 Jan;26451009
A global reference for human genetic variation.1000 Genomes Project Consortium; Auton, Adam; Brooks, Lisa D; Durbin, Richard M; Garrison, Erik P; Kang, Hyun Min; Korbel, Jan O; Marchini, Jonathan L; McCarthy, Shane; McVean, Gil A; Abecasis, Gonçalo RNature.2015 Oct 1;68-7426432245
The Mendelian disorders of the epigenetic machinery.Bjornsson, Hans TomasGenome research.2015 Oct;1473-8126430157
Creating Genome Modifications in C. elegans Using the CRISPR/Cas9 System.Calarco, John A; Friedland, Ari EMethods in molecular biology (Clifton, N.J.).2015;59-7426423968
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.Keedy, Daniel A; Kenner, Lillian R; Warkentin, Matthew; Woldeyes, Rahel A; Hopkins, Jesse B; Thompson, Michael C; Brewster, Aaron S; Van Benschoten, Andrew H; Baxter, Elizabeth L; Uervirojnangkoorn, Monarin; McPhillips, Scott E; Song, Jinhu; Alonso-Mori, Roberto; Holton, James M; Weis, William I; Brunger, Axel T; Soltis, S Michael; Lemke, Henrik; Gonzalez, Ana; Sauter, Nicholas K; Cohen, Aina E; van den Bedem, Henry; Thorne, Robert E; Fraser, James SeLife.2015;26422513
Chronic Disease Prevalence and Healthy Lifestyle Behaviors Among US Health Care Professionals.Dayoub, Elias; Jena, Anupam BMayo Clinic proceedings.2015 Dec;1659-6226422242
Dual-color photoacoustic lymph node imaging using nanoformulated naphthalocyanines.Lee, Changho; Kim, Jeesu; Zhang, Yumiao; Jeon, Mansik; Liu, Chengbo; Song, Liang; Lovell, Jonathan F; Kim, ChulhongBiomaterials.2015 Dec;142-826408999
Transcription factor competition allows embryonic stem cells to distinguish authentic signals from noise.Sokolik, Cameron; Liu, Yanxia; Bauer, David; McPherson, Jade; Broeker, Michael; Heimberg, Graham; Qi, Lei S; Sivak, David A; Thomson, MattCell systems.2015 Aug 26;117-12926405695
Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer's Disease.Quiroz, Yakeel T; Willment, Kim Celone; Castrillon, Gabriel; Muniz, Martha; Lopera, Francisco; Budson, Andrew; Stern, Chantal EJournal of Alzheimer's disease : JAD.2015;955-6426401774
Reducing Diagnostic Errors--Why Now?Khullar, Dhruv; Jha, Ashish K; Jena, Anupam BThe New England journal of medicine.2015 Dec 24;26397948
Maintaining intestinal health: the genetics and immunology of very early onset inflammatory bowel disease.Kelsen, Judith R; Baldassano, Robert N; Artis, David; Sonnenberg, Gregory FCellular and molecular gastroenterology and hepatology.2015 Sep 1;26393237
Sex Differences in Academic Rank in US Medical Schools in 2014.Jena, Anupam B; Khullar, Dhruv; Ho, Oliver; Olenski, Andrew R; Blumenthal, Daniel MJAMA.2015 Sep 15;1149-5826372584
Epithelial-intrinsic IKK? expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.Giacomin, Paul R; Moy, Ryan H; Noti, Mario; Osborne, Lisa C; Siracusa, Mark C; Alenghat, Theresa; Liu, Bigang; McCorkell, Kelly A; Troy, Amy E; Rak, Gregory D; Hu, Yinling; May, Michael J; Ma, Hak-Ling; Fouser, Lynette A; Sonnenberg, Gregory F; Artis, DavidThe Journal of experimental medicine.2015 Sep 21;1513-2826371187
The New State of the Art: Cas9 for Gene Activation and Repression.La Russa, Marie F; Qi, Lei SMolecular and cellular biology.2015 Nov;3800-926370509
Bacterial CRISPR: accomplishments and prospects.Peters, Jason M; Silvis, Melanie R; Zhao, Dehua; Hawkins, John S; Gross, Carol A; Qi, Lei SCurrent opinion in microbiology.2015 Oct;121-626363124
Access, quality, and costs of care at physician owned hospitals in the United States: observational study.Blumenthal, Daniel M; Orav, E John; Jena, Anupam B; Dudzinski, David M; Le, Sidney T; Jha, Ashish KBMJ (Clinical research ed.).2015;h446626333819
Single-Molecule RNA In Situ Hybridization (smFISH) and Immunofluorescence (IF) in the Drosophila Egg Chamber.Bayer, Livia V; Batish, Mona; Formel, Stephen K; Bratu, Diana PMethods in molecular biology (Clifton, N.J.).2015;26324434
Allosteric activation of apicomplexan calcium-dependent protein kinases.Ingram, Jessica R; Knockenhauer, Kevin E; Markus, Benedikt M; Mandelbaum, Joseph; Ramek, Alexander; Shan, Yibing; Shaw, David E; Schwartz, Thomas U; Ploegh, Hidde L; Lourido, SebastianProceedings of the National Academy of Sciences of the United States of America.2015 Sep 8;E4975-8426305940
EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.Barad, Benjamin A; Echols, Nathaniel; Wang, Ray Yu-Ruei; Cheng, Yifan; DiMaio, Frank; Adams, Paul D; Fraser, James SNature methods.2015 Oct;943-626280328
Association of Thalamic Dysconnectivity and Conversion to Psychosis in Youth and Young Adults at Elevated Clinical Risk.Anticevic, Alan; Haut, Kristen; Murray, John D; Repovs, Grega; Yang, Genevieve J; Diehl, Caroline; McEwen, Sarah C; Bearden, Carrie E; Addington, Jean; Goodyear, Bradley; Cadenhead, Kristin S; Mirzakhanian, Heline; Cornblatt, Barbara A; Olvet, Doreen; Mathalon, Daniel H; McGlashan, Thomas H; Perkins, Diana O; Belger, Aysenil; Seidman, Larry J; Tsuang, Ming T; van Erp, Theo G M; Walker, Elaine F; Hamann, Stephan; Woods, Scott W; Qiu, Maolin; Cannon, Tyrone DJAMA psychiatry.2015 Sep;26267151
Does Pain Lead to Tachycardia? Revisiting the Association Between Self-reported Pain and Heart Rate in a National Sample of Urgent Emergency Department Visits.Dayoub, Elias J; Jena, Anupam BMayo Clinic proceedings.2015 Aug;1165-626250732
From deep TLS validation to ensembles of atomic models built from elemental motions.Urzhumtsev, Alexandre; Afonine, Pavel V; Van Benschoten, Andrew H; Fraser, James S; Adams, Paul DActa crystallographica. Section D, Biological crystallography.2015 Aug;1668-8326249348
Predicting X-ray diffuse scattering from translation-libration-screw structural ensembles.Van Benschoten, Andrew H; Afonine, Pavel V; Terwilliger, Thomas C; Wall, Michael E; Jackson, Colin J; Sauter, Nicholas K; Adams, Paul D; Urzhumtsev, Alexandre; Fraser, James SActa crystallographica. Section D, Biological crystallography.2015 Aug;1657-6726249347
The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity.Meyer, Aaron S; Zweemer, Annelien J M; Lauffenburger, Douglas ACell systems.2015 Jul 29;25-3626236777
Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual-Marker Selection Cassettes.Norris, Adam D; Kim, Hyun-Min; Colaiácovo, Mónica P; Calarco, John AGenetics.2015 Oct;449-5826232410
Authorship Inflation in Medical Publications.Tilak, Gaurie; Prasad, Vinay; Jena, Anupam BInquiry : a journal of medical care organization, provision and financing.2015;26228035
An Economic Framework of Microbial Trade.Tasoff, Joshua; Mee, Michael T; Wang, Harris HPloS one.2015;e013290726222307
Selectivity in subunit composition of Ena/VASP tetramers.Riquelme, Daisy N; Meyer, Aaron S; Barzik, Melanie; Keating, Amy; Gertler, Frank BBioscience reports.2015;26221026
CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation.Liu, Honglei; Wei, Zheng; Dominguez, Antonia; Li, Yanda; Wang, Xiaowo; Qi, Lei SBioinformatics (Oxford, England).2015 Nov 15;3676-826209430
Recent Advances in Higher-Order, Multimodal, Biomedical Imaging Agents.Rieffel, James; Chitgupi, Upendra; Lovell, Jonathan FSmall (Weinheim an der Bergstrasse, Germany).2015 Sep 16;4445-6126185099
Pathway Graphical Lasso.Grechkin, Maxim; Fazel, Maryam; Witten, Daniela; Lee, Su-InProceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence.2015 Jan;2617-262326167394
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial.Freedberg, Daniel E; Toussaint, Nora C; Chen, Sway P; Ratner, Adam J; Whittier, Susan; Wang, Timothy C; Wang, Harris H; Abrams, Julian AGastroenterology.2015 Jul 8;26164495
Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.Yaung, Stephanie J; Deng, Luxue; Li, Ning; Braff, Jonathan L; Church, George M; Bry, Lynn; Wang, Harris H; Gerber, Georg KMolecular systems biology.2015 Mar;26148351
?2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.Smith, Lucas K; He, Yingbo; Park, Jeong-Soo; Bieri, Gregor; Snethlage, Cedric E; Lin, Karin; Gontier, Geraldine; Wabl, Rafael; Plambeck, Kristopher E; Udeochu, Joe; Wheatley, Elizabeth G; Bouchard, Jill; Eggel, Alexander; Narasimha, Ramya; Grant, Jacqueline L; Luo, Jian; Wyss-Coray, Tony; Villeda, Saul ANature medicine.2015 Aug;932-726147761
Innate lymphoid cells in the initiation, regulation and resolution of inflammation.Sonnenberg, Gregory F; Artis, DavidNature medicine.2015 Jul;698-70826121198
Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study.Quiroz, Yakeel T; Schultz, Aaron P; Chen, Kewei; Protas, Hillary D; Brickhouse, Michael; Fleisher, Adam S; Langbaum, Jessica B; Thiyyagura, Pradeep; Fagan, Anne M; Shah, Aarti R; Muniz, Martha; Arboleda-Velasquez, Joseph F; Munoz, Claudia; Garcia, Gloria; Acosta-Baena, Natalia; Giraldo, Margarita; Tirado, Victoria; Ramírez, Dora L; Tariot, Pierre N; Dickerson, Bradford C; Sperling, Reisa A; Lopera, Francisco; Reiman, Eric MJAMA neurology.2015 Aug;912-926121081
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.Kang, Seokwon; Fernandes-Alnemri, Teresa; Rogers, Corey; Mayes, Lindsey; Wang, Ying; Dillon, Christopher; Roback, Linda; Kaiser, William; Oberst, Andrew; Sagara, Junji; Fitzgerald, Katherine A; Green, Douglas R; Zhang, Jianke; Mocarski, Edward S; Alnemri, Emad SNature communications.2015;26104484
Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.Antonopoulos, Christina; Russo, Hana M; El Sanadi, Caroline; Martin, Bradley N; Li, Xiaoxia; Kaiser, William J; Mocarski, Edward S; Dubyak, George RThe Journal of biological chemistry.2015 Aug 14;20167-8426100631
Contributions of risk factors and medical care to cardiovascular mortality trends.Ezzati, Majid; Obermeyer, Ziad; Tzoulaki, Ioanna; Mayosi, Bongani M; Elliott, Paul; Leon, David ANature reviews. Cardiology.2015 Sep;26076950
Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting.Chitgupi, Upendra; Zhang, Yumiao; Lo, Chi Y; Shao, Shuai; Song, Wentao; Geng, Jumin; Neelamegham, Sriram; Lovell, Jonathan FBioconjugate chemistry.2015 Aug 19;1633-926057017
Physician Characteristics Strongly Predict Patient Enrollment In Hospice.Obermeyer, Ziad; Powers, Brian W; Makar, Maggie; Keating, Nancy L; Cutler, David MHealth affairs (Project Hope).2015 Jun;993-100026056205
Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance.Moreno-Gamez, Stefany; Hill, Alison L; Rosenbloom, Daniel I S; Petrov, Dmitri A; Nowak, Martin A; Pennings, Pleuni SProceedings of the National Academy of Sciences of the United States of America.2015 Jun 2;E2874-8326038564
Ketamine as a Prophylactic Against Stress-Induced Depressive-Like Behavior.Brachman, Rebecca A; McGowan, Josephine C; Perusini, Jennifer N; Lim, Sean C; Pham, Thu Ha; Faye, Charlene; Gardier, Alain M; Mendez-David, Indira; David, Denis J; Hen, René; Denny, Christine ABiological psychiatry.2015 May 4;26037911
One Crystal, Two Temperatures: Cryocooling Penalties Alter Ligand Binding to Transient Protein Sites.Fischer, Marcus; Shoichet, Brian K; Fraser, James SChembiochem : a European journal of chemical biology.2015 Jul 27;1560-426032594
Prion-Protein-interacting Amyloid-? Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models.Kostylev, Mikhail A; Kaufman, Adam C; Nygaard, Haakon B; Patel, Pujan; Haas, Laura T; Gunther, Erik C; Vortmeyer, Alexander; Strittmatter, Stephen MThe Journal of biological chemistry.2015 Jul 10;17415-3826018073
Negative Epistasis and Evolvability in TEM-1 *-Lactamase-The Thin Line between an Enzyme's Conformational Freedom and Disorder.Dellus-Gur, Eynat; Elias, Mikael; Caselli, Emilia; Prati, Fabio; Salverda, Merijn L M; de Visser, J Arjan G M; Fraser, James S; Tawfik, Dan SJournal of molecular biology.2015 Jul 17;2396-40926004540
Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors.Chang, ZeNan L; Silver, Pamela A; Chen, Yvonne YJournal of translational medicine.2015;25990251
Frequency of ED revisits and death among older adults after a fall.Liu, Shan W; Obermeyer, Ziad; Chang, Yuchiao; Shankar, Kalpana NThe American journal of emergency medicine.2015 Aug;25983268
Targeted Transcriptional Repression in Bacteria Using CRISPR Interference (CRISPRi).Hawkins, John S; Wong, Spencer; Peters, Jason M; Almeida, Ricardo; Qi, Lei SMethods in molecular biology (Clifton, N.J.).2015;349-6225981485
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.Kane, Joshua R; Stanley, David J; Hultquist, Judd F; Johnson, Jeffrey R; Mietrach, Nicole; Binning, Jennifer M; Jónsson, Stefán R; Barelier, Sarah; Newton, Billy W; Johnson, Tasha L; Franks-Skiba, Kathleen E; Li, Ming; Brown, William L; Gunnarsson, Hörður I; Adalbjornsdóttir, Adalbjorg; Fraser, James S; Harris, Reuben S; Andrésdóttir, Valgerður; Gross, John D; Krogan, Nevan JCell reports.2015 May 26;1236-5025981045
The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.Gold, Daniel A; Kaplan, Aaron D; Lis, Agnieszka; Bett, Glenna C L; Rosowski, Emily E; Cirelli, Kimberly M; Bougdour, Alexandre; Sidik, Saima M; Beck, Josh R; Lourido, Sebastian; Egea, Pascal F; Bradley, Peter J; Hakimi, Mohamed-Ali; Rasmusson, Randall L; Saeij, Jeroen P JCell host & microbe.2015 May 13;642-5225974303
The Impact of the US Food and Drug Administration Chlorofluorocarbon Ban on Out-of-pocket Costs and Use of Albuterol Inhalers Among Individuals With Asthma.Jena, Anupam B; Ho, Oliver; Goldman, Dana P; Karaca-Mandic, PinarJAMA internal medicine.2015 Jul;1171-925962128
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.McHugh, Colleen A; Chen, Chun-Kan; Chow, Amy; Surka, Christine F; Tran, Christina; McDonel, Patrick; Pandya-Jones, Amy; Blanco, Mario; Burghard, Christina; Moradian, Annie; Sweredoski, Michael J; Shishkin, Alexander A; Su, Julia; Lander, Eric S; Hess, Sonja; Plath, Kathrin; Guttman, MitchellNature.2015 May 14;232-625915022
Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4? T cells.Hepworth, Matthew R; Fung, Thomas C; Masur, Samuel H; Kelsen, Judith R; McConnell, Fiona M; Dubrot, Juan; Withers, David R; Hugues, Stephanie; Farrar, Michael A; Reith, Walter; Eberl, Gérard; Baldassano, Robert N; Laufer, Terri M; Elson, Charles O; Sonnenberg, Gregory FScience (New York, N.Y.).2015 May 29;1031-525908663
Functionalization of cobalt porphyrin-phospholipid bilayers with his-tagged ligands and antigens.Shao, Shuai; Geng, Jumin; Ah Yi, Hyun; Gogia, Shobhit; Neelamegham, Sriram; Jacobs, Amy; Lovell, Jonathan FNature chemistry.2015 May;438-4625901823
Pervasive Heavy Alcohol Use and Correlates of Increasing Levels of Binge Drinking among Men Who Have Sex with Men, San Francisco, 2011.Santos, Glenn-Milo; Jin, Harry; Raymond, H FisherJournal of urban health : bulletin of the New York Academy of Medicine.2015 Aug;687-70025895622
Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins.Wang, Eric T; Ward, Amanda J; Cherone, Jennifer M; Giudice, Jimena; Wang, Thomas T; Treacy, Daniel J; Lambert, Nicole J; Freese, Peter; Saxena, Tanvi; Cooper, Thomas A; Burge, Christopher BGenome research.2015 Jun;858-7125883322
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.Yano, Jessica M; Yu, Kristie; Donaldson, Gregory P; Shastri, Gauri G; Ann, Phoebe; Ma, Liang; Nagler, Cathryn R; Ismagilov, Rustem F; Mazmanian, Sarkis K; Hsiao, Elaine YCell.2015 Apr 9;264-7625860609
The Diversity of Meningococcal Carriage Across the African Meningitis Belt and the Impact of Vaccination With a Group A Meningococcal Conjugate Vaccine.MenAfriCar consortiumThe Journal of infectious diseases.2015 Apr 9;25858956
Manipulation of apoptosis and necroptosis signaling by herpesviruses.Guo, Hongyan; Kaiser, William J; Mocarski, Edward SMedical microbiology and immunology.2015 Jun;439-4825828583
Integrative, dynamic structural biology at atomic resolution--it's about time.van den Bedem, Henry; Fraser, James SNature methods.2015 Apr;307-1825825836
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.Laird, Gregory M; Bullen, C Korin; Rosenbloom, Daniel I S; Martin, Alyssa R; Hill, Alison L; Durand, Christine M; Siliciano, Janet D; Siliciano, Robert FThe Journal of clinical investigation.2015 May;1901-1225822022
Necroptosis: The Trojan horse in cell autonomous antiviral host defense.Mocarski, Edward S; Guo, Hongyan; Kaiser, William JVirology.2015 May;160-625819165
Cost savings associated with expanded hospice use in Medicare.Powers, Brian W; Makar, Maggie; Jain, Sachin H; Cutler, David M; Obermeyer, ZiadJournal of palliative medicine.2015 May;400-125806563
Suppression of RIP3-dependent necroptosis by human cytomegalovirus.Omoto, Shinya; Guo, Hongyan; Talekar, Ganesh R; Roback, Linda; Kaiser, William J; Mocarski, Edward SThe Journal of biological chemistry.2015 May 1;11635-4825778401
Codon optimality is a major determinant of mRNA stability.Presnyak, Vladimir; Alhusaini, Najwa; Chen, Ying-Hsin; Martin, Sophie; Morris, Nathan; Kline, Nicholas; Olson, Sara; Weinberg, David; Baker, Kristian E; Graveley, Brenton R; Coller, JeffCell.2015 Mar 12;1111-2425768907
Autophagy Controls Acquisition of Aging Features in Macrophages.Stranks, Amanda J; Hansen, Anne Louise; Panse, Isabel; Mortensen, Monika; Ferguson, David J P; Puleston, Daniel J; Shenderov, Kevin; Watson, Alexander Scarth; Veldhoen, Marc; Phadwal, Kanchan; Cerundolo, Vincenzo; Simon, Anna KatharinaJournal of innate immunity.2015;375-9125764971
Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.Yaung, Stephanie J; Deng, Luxue; Li, Ning; Braff, Jonathan L; Church, George M; Bry, Lynn; Wang, Harris H; Gerber, Georg KMolecular systems biology.2015 Jan;25762151
Simultaneous generation of many RNA-seq libraries in a single reaction.Shishkin, Alexander A; Giannoukos, Georgia; Kucukural, Alper; Ciulla, Dawn; Busby, Michele; Surka, Christine; Chen, Jenny; Bhattacharyya, Roby P; Rudy, Robert F; Patel, Milesh M; Novod, Nathaniel; Hung, Deborah T; Gnirke, Andreas; Garber, Manuel; Guttman, Mitchell; Livny, JonathanNature methods.2015 Apr;323-525730492
Divorce among physicians and other healthcare professionals in the United States: analysis of census survey data.Ly, Dan P; Seabury, Seth A; Jena, Anupam BBMJ (Clinical research ed.).2015;h70625694110
Herpes simplex virus suppresses necroptosis in human cells.Guo, Hongyan; Omoto, Shinya; Harris, Philip A; Finger, Joshua N; Bertin, John; Gough, Peter J; Kaiser, William J; Mocarski, Edward SCell host & microbe.2015 Feb 11;243-5125674983
Incidence of sexually transmitted infections after human papillomavirus vaccination among adolescent females.Jena, Anupam B; Goldman, Dana P; Seabury, Seth AJAMA internal medicine.2015 Apr;617-2325664968
Small molecules enhance CRISPR genome editing in pluripotent stem cells.Yu, Chen; Liu, Yanxia; Ma, Tianhua; Liu, Kai; Xu, Shaohua; Zhang, Yu; Liu, Honglei; La Russa, Marie; Xie, Min; Ding, Sheng; Qi, Lei SCell stem cell.2015 Feb 5;142-725658371
The cluster graphical lasso for improved estimation of Gaussian graphical models.Tan, Kean Ming; Witten, Daniela; Shojaie, AliComputational statistics & data analysis.2015 May;23-3625642008
Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles.Rieffel, James; Chen, Feng; Kim, Jeesu; Chen, Guanying; Shao, Wei; Shao, Shuai; Chitgupi, Upendra; Hernandez, Reinier; Graves, Stephen A; Nickles, Robert J; Prasad, Paras N; Kim, Chulhong; Cai, Weibo; Lovell, Jonathan FAdvanced materials (Deerfield Beach, Fla.).2015 Mar 11;1785-9025640213
Validation of in vivo 2D displacements from spiral cine DENSE at 3T.Wehner, Gregory J; Suever, Jonathan D; Haggerty, Christopher M; Jing, Linyuan; Powell, David K; Hamlet, Sean M; Grabau, Jonathan D; Mojsejenko, Walter Dimitri; Zhong, Xiaodong; Epstein, Frederick H; Fornwalt, Brandon KJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.2015;25634468
A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity.Cerchiari, Alec E; Garbe, James C; Jee, Noel Y; Todhunter, Michael E; Broaders, Kyle E; Peehl, Donna M; Desai, Tejal A; LaBarge, Mark A; Thomson, Matthew; Gartner, Zev JProceedings of the National Academy of Sciences of the United States of America.2015 Feb 17;2287-9225633040
Mandatory use of prescription drug monitoring programs.Haffajee, Rebecca L; Jena, Anupam B; Weiner, Scott GJAMA.2015 Mar 3;891-225622279
Protein glycosylation in cancer.Stowell, Sean R; Ju, Tongzhong; Cummings, Richard DAnnual review of pathology.2015;473-51025621663
Learning Graphical Models With Hubs.Tan, Kean Ming; London, Palma; Mohan, Karthik; Lee, Su-In; Fazel, Maryam; Witten, DanielaJournal of machine learning research : JMLR.2014 Oct;3297-333125620891
Quantitative visualization of alternative exon expression from RNA-seq data.Katz, Yarden; Wang, Eric T; Silterra, Jacob; Schwartz, Schraga; Wong, Bang; Thorvaldsdóttir, Helga; Robinson, James T; Mesirov, Jill P; Airoldi, Edoardo M; Burge, Christopher BBioinformatics (Oxford, England).2015 Jul 15;2400-225617416
The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium spp.Lourido, Sebastian; Moreno, Silvia N JCell calcium.2015 Mar;186-9325605521
Identifying mutation specific cancer pathways using a structurally resolved protein interaction network.Engin, H Billur; Hofree, Matan; Carter, HannahPacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.2015;84-9525592571
Evolution and emergence of infectious diseases in theoretical and real-world networks.Leventhal, Gabriel E; Hill, Alison L; Nowak, Martin A; Bonhoeffer, SebastianNature communications.2015;25592476
CCR7-dependent trafficking of RORýýýýý ILCs creates a unique microenvironment within mucosal draining lymph nodes.Mackley, Emma C; Houston, Stephanie; Marriott, Clare L; Halford, Emily E; Lucas, Beth; Cerovic, Vuk; Filbey, Kara J; Maizels, Rick M; Hepworth, Matthew R; Sonnenberg, Gregory F; Milling, Simon; Withers, David RNature communications.2015;25575242
Keep on moving: discovering and perturbing the conformational dynamics of enzymes.Bhabha, Gira; Biel, Justin T; Fraser, James SAccounts of chemical research.2015 Feb 17;423-3025539415
Cause-specific risk of hospital admission related to extreme heat in older adults.Bobb, Jennifer F; Obermeyer, Ziad; Wang, Yun; Dominici, FrancescaJAMA.2014 Dec 24-31;2659-6725536257
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.Brestoff, Jonathan R; Kim, Brian S; Saenz, Steven A; Stine, Rachel R; Monticelli, Laurel A; Sonnenberg, Gregory F; Thome, Joseph J; Farber, Donna L; Lutfy, Kabirullah; Seale, Patrick; Artis, DavidNature.2015 Mar 12;242-625533952
Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.Zalatan, Jesse G; Lee, Michael E; Almeida, Ricardo; Gilbert, Luke A; Whitehead, Evan H; La Russa, Marie; Tsai, Jordan C; Weissman, Jonathan S; Dueber, John E; Qi, Lei S; Lim, Wendell ACell.2015 Jan 15;339-5025533786
Mortality and treatment patterns among patients hospitalized with acute cardiovascular conditions during dates of national cardiology meetings.Jena, Anupam B; Prasad, Vinay; Goldman, Dana P; Romley, JohnJAMA internal medicine.2015 Feb;237-4425531231
Genomic analysis of RNA localization.Taliaferro, J Matthew; Wang, Eric T; Burge, Christopher BRNA biology.2014;1040-5025483039
Germline signals deploy NHR-49 to modulate fatty-acid *-oxidation and desaturation in somatic tissues of C. elegans.Ratnappan, Ramesh; Amrit, Francis R G; Chen, Shaw-Wen; Gill, Hasreet; Holden, Kyle; Ward, Jordan; Yamamoto, Keith R; Olsen, Carissa P; Ghazi, ArjumandPLoS genetics.2014 Dec;e100482925474470
RIP3 induces apoptosis independent of pronecrotic kinase activity.Mandal, Pratyusha; Berger, Scott B; Pillay, Sirika; Moriwaki, Kenta; Huang, Chunzi; Guo, Hongyan; Lich, John D; Finger, Joshua; Kasparcova, Viera; Votta, Bart; Ouellette, Michael; King, Bryan W; Wisnoski, David; Lakdawala, Ami S; DeMartino, Michael P; Casillas, Linda N; Haile, Pamela A; Sehon, Clark A; Marquis, Robert W; Upton, Jason; Daley-Bauer, Lisa P; Roback, Linda; Ramia, Nancy; Dovey, Cole M; Carette, Jan E; Chan, Francis Ka-Ming; Bertin, John; Gough, Peter J; Mocarski, Edward S; Kaiser, William JMolecular cell.2014 Nov 20;481-9525459880
Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering.Wall, Michael E; Van Benschoten, Andrew H; Sauter, Nicholas K; Adams, Paul D; Fraser, James S; Terwilliger, Thomas CProceedings of the National Academy of Sciences of the United States of America.2014 Dec 16;17887-9225453071
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Simplified post processing of cine DENSE cardiovascular magnetic resonance for quantification of cardiac mechanics.Suever, Jonathan D; Wehner, Gregory J; Haggerty, Christopher M; Jing, Linyuan; Hamlet, Sean M; Binkley, Cassi M; Kramer, Sage P; Mattingly, Andrea C; Powell, David K; Bilchick, Kenneth C; Epstein, Frederick H; Fornwalt, Brandon KJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.2014;25430079
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Specific gene repression by CRISPRi system transferred through bacterial conjugation.Ji, Weiyue; Lee, Derrick; Wong, Eric; Dadlani, Priyanka; Dinh, David; Huang, Verna; Kearns, Kendall; Teng, Sherry; Chen, Susan; Haliburton, John; Heimberg, Graham; Heineike, Benjamin; Ramasubramanian, Anusuya; Stevens, Thomas; Helmke, Kara J; Zepeda, Veronica; Qi, Lei S; Lim, Wendell AACS synthetic biology.2014 Dec 19;929-3125409531
The Peltzman effect and compensatory markers in medicine.Prasad, Vinay; Jena, Anupam BHealthcare (Amsterdam, Netherlands).2014 Sep 1;170-17225396116
Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.Stieglitz, Elliot; Troup, Camille B; Gelston, Laura C; Haliburton, John; Chow, Eric D; Yu, Kristie B; Akutagawa, Jon; Taylor-Weiner, Amaro N; Liu, Y Lucy; Wang, Yong-Dong; Beckman, Kyle; Emanuel, Peter D; Braun, Benjamin S; Abate, Adam; Gerbing, Robert B; Alonzo, Todd A; Loh, Mignon LBlood.2015 Jan 15;516-2425395418
tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae.Damon, Jadyn R; Pincus, David; Ploegh, Hidde LMolecular biology of the cell.2015 Jan 15;270-8225392298
Prediction of resistance development against drug combinations by collateral responses to component drugs.Munck, Christian; Gumpert, Heidi K; Wallin, Annika I Nilsson; Wang, Harris H; Sommer, Morten O AScience translational medicine.2014 Nov 12;262ra15625391482
Association between the Medicare hospice benefit and health care utilization and costs for patients with poor-prognosis cancer.Obermeyer, Ziad; Makar, Maggie; Abujaber, Samer; Dominici, Francesca; Block, Susan; Cutler, David MJAMA.2014 Nov 12;1888-9625387186
Nanomedical engineering: shaping future nanomedicines.Luo, Dandan; Carter, Kevin A; Lovell, Jonathan FWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.2015 Mar-Apr;169-8825377691
A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis.Wu, Wesley; Herrera, Zachary; Ebert, Danny; Baska, Katie; Cho, Seok H; DeRisi, Joseph L; Yeh, EllenAntimicrobial agents and chemotherapy.2015 Jan;356-6425367906
Sparse Biclustering of Transposable Data.Tan, Kean Ming; Witten, Daniela MJournal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America.2014;985-100825364221
One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism.Swee, Lee Kim; Lourido, Sebastian; Bell, George W; Ingram, Jessica R; Ploegh, Hidde LACS chemical biology.2015 Feb 20;460-525360987
Structured Learning of Gaussian Graphical Models.Mohan, Karthik; Chung, Michael Jae-Yoon; Han, Seungyeop; Witten, Daniela; Lee, Su-In; Fazel, MaryamAdvances in neural information processing systems.2012;629-63725360066
The genomic landscape of polymorphic human nuclear mitochondrial insertions.Dayama, Gargi; Emery, Sarah B; Kidd, Jeffrey M; Mills, Ryan ENucleic acids research.2014 Nov 10;12640-925348406
Medical malpractice reform: noneconomic damages caps reduced payments 15 percent, with varied effects by specialty.Seabury, Seth A; Helland, Eric; Jena, Anupam BHealth affairs (Project Hope).2014 Nov;2048-5625339633
Aging and brain rejuvenation as systemic events.Bouchard, Jill; Villeda, Saul AJournal of neurochemistry.2015 Jan;25327899
Transfer of noncoding DNA drives regulatory rewiring in bacteria.Oren, Yaara; Smith, Mark B; Johns, Nathan I; Kaplan Zeevi, Millie; Biran, Dvora; Ron, Eliora Z; Corander, Jukka; Wang, Harris H; Alm, Eric J; Pupko, TalProceedings of the National Academy of Sciences of the United States of America.2014 Nov 11;16112-725313052
Node-Based Learning of Multiple Gaussian Graphical Models.Mohan, Karthik; London, Palma; Fazel, Maryam; Witten, Daniela; Lee, Su-InJournal of machine learning research : JMLR.2014 Jan 1;445-48825309137
A protein-tagging system for signal amplification in gene expression and fluorescence imaging.Tanenbaum, Marvin E; Gilbert, Luke A; Qi, Lei S; Weissman, Jonathan S; Vale, Ronald DCell.2014 Oct 23;635-4625307933
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.Gilbert, Luke A; Horlbeck, Max A; Adamson, Britt; Villalta, Jacqueline E; Chen, Yuwen; Whitehead, Evan H; Guimaraes, Carla; Panning, Barbara; Ploegh, Hidde L; Bassik, Michael C; Qi, Lei S; Kampmann, Martin; Weissman, Jonathan SCell.2014 Oct 23;647-6125307932
Characterizing immune repertoires by high throughput sequencing: strategies and applications.Calis, Jorg J A; Rosenberg, Brad RTrends in immunology.2014 Oct 8;581-59025306219
Exposing physicians to reduced residency work hours did not adversely affect patient outcomes after residency.Jena, Anupam B; Schoemaker, Lena; Bhattacharya, JayHealth affairs (Project Hope).2014 Oct;1832-4025288430
Thermal green protein, an extremely stable, nonaggregating fluorescent protein created by structure-guided surface engineering.Close, Devin W; Paul, Craig Don; Langan, Patricia S; Wilce, Matthew C J; Traore, Daouda A K; Halfmann, Randal; Rocha, Reginaldo C; Waldo, Geoffery S; Payne, Riley J; Rucker, Joseph B; Prescott, Mark; Bradbury, Andrew R MProteins.2015 Jul;1225-3725287913
Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.Bjornsson, Hans T; Benjamin, Joel S; Zhang, Li; Weissman, Jacqueline; Gerber, Elizabeth E; Chen, Yi-Chun; Vaurio, Rebecca G; Potter, Michelle C; Hansen, Kasper D; Dietz, Harry CScience translational medicine.2014 Oct 1;256ra13525273096
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine.Williams, Brianna B; Van Benschoten, Andrew H; Cimermancic, Peter; Donia, Mohamed S; Zimmermann, Michael; Taketani, Mao; Ishihara, Atsushi; Kashyap, Purna C; Fraser, James S; Fischbach, Michael ACell host & microbe.2014 Oct 8;495-50325263219
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.Engreitz, Jesse M; Sirokman, Klara; McDonel, Patrick; Shishkin, Alexander A; Surka, Christine; Russell, Pamela; Grossman, Sharon R; Chow, Amy Y; Guttman, Mitchell; Lander, Eric SCell.2014 Sep 25;188-9925259926
Environmental statistics and optimal regulation.Sivak, David A; Thomson, MattPLoS computational biology.2014 Sep;e100382625254493
Association between treatment toxicity and outcomes in oncology clinical trials.Abola, M V; Prasad, V; Jena, A BAnnals of oncology : official journal of the European Society for Medical Oncology / ESMO.2014 Nov;2284-925193993
Abnormalities of the DNA methylation mark and its machinery: an emerging cause of neurologic dysfunction.Weissman, Jacqueline; Naidu, Sakkubai; Bjornsson, Hans TSeminars in neurology.2014 Jul;249-5725192503
Mendelian disorders of the epigenetic machinery: tipping the balance of chromatin states.Fahrner, Jill A; Bjornsson, Hans TAnnual review of genomics and human genetics.2014;269-9325184531
Transcriptome sequencing from diverse human populations reveals differentiated regulatory architecture.Martin, Alicia R; Costa, Helio A; Lappalainen, Tuuli; Henn, Brenna M; Kidd, Jeffrey M; Yee, Muh-Ching; Grubert, Fabian; Cann, Howard M; Snyder, Michael; Montgomery, Stephen B; Bustamante, Carlos DPLoS genetics.2014 Aug;e100454925121757
E pluribus unum, no more: from one crystal, many conformations.Woldeyes, Rahel A; Sivak, David A; Fraser, James SCurrent opinion in structural biology2014 Aug 856-6225113271
Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1.Hill, Alison L; Rosenbloom, Daniel I S; Fu, Feng; Nowak, Martin A; Siliciano, Robert FProceedings of the National Academy of Sciences of the United States of America.2014 Sep 16;13475-8025097264
Turning evidence into practice under payment reform: the new frontier of translational science.Jena, Anupam B; Stevens, Warren; McWilliams, J MichaelJournal of general internal medicine.2014 Nov;1542-525092013
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.Gross, Andrew M; Orosco, Ryan K; Shen, John P; Egloff, Ann Marie; Carter, Hannah; Hofree, Matan; Choueiri, Michel; Coffey, Charles S; Lippman, Scott M; Hayes, D Neil; Cohen, Ezra E; Grandis, Jennifer R; Nguyen, Quyen T; Ideker, TreyNature genetics.2014 Sep;939-4325086664
Graph Estimation with Joint Additive Models.Voorman, Arend; Shojaie, Ali; Witten, DanielaBiometrika2014 Mar 185-10125013234
Inferring clonal composition from multiple sections of a breast cancer.Zare, Habil; Wang, Junfeng; Hu, Alex; Weber, Kris; Smith, Josh; Nickerson, Debbie; Song, ChaoZhong; Witten, Daniela; Blau, C Anthony; Noble, William StaffordPLoS computational biology2014 Jule100370325010360
Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines.Zhang, Yumiao; Jeon, Mansik; Rich, Laurie J; Hong, Hao; Geng, Jumin; Zhang, Yin; Shi, Sixiang; Barnhart, Todd E; Alexandridis, Paschalis; Huizinga, Jan D; Seshadri, Mukund; Cai, Weibo; Kim, Chulhong; Lovell, Jonathan FNature nanotechnology.2014 Aug;631-824997526
Patients with repaired tetralogy of Fallot suffer from intra- and inter-ventricular cardiac dyssynchrony: a cardiac magnetic resonance study.Jing, Linyuan; Haggerty, Christopher M; Suever, Jonathan D; Alhadad, Sudad; Prakash, Ashwin; Cecchin, Frank; Skrinjar, Oskar; Geva, Tal; Powell, Andrew J; Fornwalt, Brandon KEuropean heart journal cardiovascular Imaging2014 Jul 4NULL24996664
Long-term effects of the 2003 ACGME resident duty hour reform on hospital mortality.Jena, Anupam B; Prasad, Vinay; Romley, John AMayo Clinic proceedings2014 Jul1023-524996240
Efficient Genome Engineering of Toxoplasma gondii Using CRISPR/Cas9.Sidik, Saima M; Hackett, Caroline G; Tran, Fanny; Westwood, Nicholas J; Lourido, SebastianPloS one2014e10045024971596
Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.Fischer, Marcus; Coleman, Ryan G; Fraser, James S; Shoichet, Brian KNature chemistry2014 Jul575-8324950326
Anatomical localization of commensal bacteria in immune cell homeostasis and disease.Fung, Thomas C; Artis, David; Sonnenberg, Gregory FImmunological reviews2014 Jul35-4924942680
Quantification of left ventricular volumes, mass, and ejection fraction using cine displacement encoding with stimulated echoes (DENSE) MRI.Haggerty, Christopher M; Kramer, Sage P; Skrinjar, Oskar; Binkley, Cassi M; Powell, David K; Mattingly, Andrea C; Epstein, Frederick H; Fornwalt, Brandon KJournal of magnetic resonance imaging : JMRI2014 Aug398-40624923710
A Pair of RNA-Binding Proteins Controls Networks of Splicing Events Contributing to Specialization of Neural Cell Types.Norris, Adam D; Gao, Shangbang; Norris, Megan L; Ray, Debashish; Ramani, Arun K; Fraser, Andrew G; Morris, Quaid; Hughes, Timothy R; Zhen, Mei; Calarco, John AMolecular cell2014 Jun 4NULL24910101
Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.Keedy, Daniel A; van den Bedem, Henry; Sivak, David A; Petsko, Gregory A; Ringe, Dagmar; Wilson, Mark A; Fraser, James SStructure (London, England : 1993)2014 Jun 10899-91024882744
The Declining Demand for Hospital Care as a Rationale for Duty Hour Reform.Jena, Anupam B; DePasse, Jacqueline W; Prasad, VinayJournal of general internal medicine2014 May 28NULL24866469
The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.Wang, Haikun; Geng, Jianlin; Wen, Xiaomin; Bi, Enguang; Kossenkov, Andrew V; Wolf, Amaya I; Tas, Jeroen; Choi, Youn Soo; Takata, Hiroshi; Day, Timothy J; Chang, Li-Yuan; Sprout, Stephanie L; Becker, Emily K; Willen, Jessica; Tian, Lifeng; Wang, Xinxin; XiNature immunology2014 Jul667-7524859450
Direct Mutagenesis of Thousands of Genomic Targets Using Microarray-Derived Oligonucleotides.Bonde, Mads T; Kosuri, Sriram; Genee, Hans J; Sarup-Lytzen, Kira; Church, George M; Sommer, Morten O A; Wang, Harris HACS synthetic biology2014 Jun 20NULL24856730
A versatile framework for microbial engineering using synthetic non-coding RNAs.Qi, Lei S; Arkin, Adam PNature reviews. Microbiology2014 May341-5424847554
Recent progress in engineering human-associated microbiomes.Yaung, Stephanie J; Church, George M; Wang, Harris HMethods in molecular biology (Clifton, N.J.)201425-Mar24838875
MODEST: a web-based design tool for oligonucleotide-mediated genome engineering and recombineering.Bonde, Mads T; Klausen, Michael S; Anderson, Mads V; Wallin, Annika I N; Wang, Harris H; Sommer, Morten O ANucleic acids research2014 JulW408-1524838561
Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice.Berger, Scott B; Kasparcova, Viera; Hoffman, Sandy; Swift, Barb; Dare, Lauren; Schaeffer, Michelle; Capriotti, Carol; Cook, Michael; Finger, Joshua; Hughes-Earle, Angela; Harris, Philip A; Kaiser, William J; Mocarski, Edward S; Bertin, John; Gough, Peter Journal of immunology (Baltimore, Md. : 1950)2014 May 12NULL24821972
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition.Kaiser, William J; Daley-Bauer, Lisa P; Thapa, Roshan J; Mandal, Pratyusha; Berger, Scott B; Huang, Chunzi; Sundararajan, Aarthi; Guo, Hongyan; Roback, Linda; Speck, Samuel H; Bertin, John; Gough, Peter J; Balachandran, Siddharth; Mocarski, Edward SProceedings of the National Academy of Sciences of the United States of America2014 May 277753-824821786
Regulation of intestinal health and disease by innate lymphoid cells.Sonnenberg, Gregory FInternational immunology2014 Sep501-50724821261
The joint graphical lasso for inverse covariance estimation across multiple classes.Danaher, Patrick; Wang, Pei; Witten, Daniela MJournal of the Royal Statistical Society. Series B, Statistical methodology2014 Mar373-39724817823
The Cluster Elastic Net for High-Dimensional Regression With Unknown Variable Grouping.Witten, Daniela M; Shojaie, Ali; Zhang, FanTechnometrics : a journal of statistics for the physical, chemical, and engineering sciences2014 Feb 20112-12224817772
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.Weng, Dan; Marty-Roix, Robyn; Ganesan, Sandhya; Proulx, Megan K; Vladimer, Gregory I; Kaiser, William J; Mocarski, Edward S; Pouliot, Kimberly; Chan, Francis Ka-Ming; Kelliher, Michelle A; Harris, Phillip A; Bertin, John; Gough, Peter J; Shayakhmetov, Dmitry M; Goguen, Jon D; Fitzgerald, Katherine A; Silverman, Neal; Lien, EgilProceedings of the National Academy of Sciences of the United States of America.2014 May 20;7391-624799678
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.Villeda, Saul A; Plambeck, Kristopher E; Middeldorp, Jinte; Castellano, Joseph M; Mosher, Kira I; Luo, Jian; Smith, Lucas K; Bieri, Gregor; Lin, Karin; Berdnik, Daniela; Wabl, Rafael; Udeochu, Joe; Wheatley, Elizabeth G; Zou, Bende; Simmons, Danielle A; Xie, Xinmin S; Longo, Frank M; Wyss-Coray, TonyNature medicine.2014 Jun;659-6324793238
Syntrophic exchange in synthetic microbial communities.Mee, Michael T; Collins, James J; Church, George M; Wang, Harris HProceedings of the National Academy of Sciences of the United States of America2014 May 20E2149-5624778240
Medical professional liability risk among US cardiologists.Mangalmurti, Sandeep; Seabury, Seth A; Chandra, Amitabh; Lakdawalla, Darius; Oetgen, William J; Jena, Anupam BAmerican heart journal2014 May690-624766979
Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.Giudice, Jimena; Xia, Zheng; Wang, Eric T; Scavuzzo, Marissa A; Ward, Amanda J; Kalsotra, Auinash; Wang, Wei; Wehrens, Xander H T; Burge, Christopher B; Li, Wei; Cooper, Thomas ANature communications2014360324752171
A versatile framework for microbial engineering using synthetic non-coding RNAs.Qi, Lei S; Arkin, Adam PNature reviews. Microbiology2014 May341-5424736794
Exome capture from saliva produces high quality genomic and metagenomic data.Kidd, Jeffrey M; Sharpton, Thomas J; Bobo, Dean; Norman, Paul J; Martin, Alicia R; Carpenter, Meredith L; Sikora, Martin; Gignoux, Christopher R; Nemat-Gorgani, Neda; Adams, Alexandra; Guadalupe, Moraima; Guo, Xiaosen; Feng, Qiang; Li, Yingrui; Liu, Xiao;BMC genomics201426224708091
Porphyrin-phospholipid liposomes permeabilized by near-infrared light.Carter, Kevin A; Shao, Shuai; Hoopes, Matthew I; Luo, Dandan; Ahsan, Bilal; Grigoryants, Vladimir M; Song, Wentao; Huang, Haoyuan; Zhang, Guojian; Pandey, Ravindra K; Geng, Jumin; Pfeifer, Blaine A; Scholes, Charles P; Ortega, Joaquin; Karttunen, Mikko; LNature communications2014354624699423
Clonal and cellular dynamics in germinal centers.Victora, Gabriel D; Mesin, LukaCurrent opinion in immunology2014 Mar 2690-9624681449
Fusion FISH imaging: single-molecule detection of gene fusion transcripts in situ.Markey, Fatu Badiane; Ruezinsky, William; Tyagi, Sanjay; Batish, MonaPloS one2014e9348824675777
Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.Cai, Xin; Chen, Jueqi; Xu, Hui; Liu, Siqi; Jiang, Qiu-Xing; Halfmann, Randal; Chen, Zhijian JCell2014 Mar 131207-2224630723
Regulation of the adaptive immune system by innate lymphoid cells.Hepworth, Matthew R; Sonnenberg, Gregory FCurrent opinion in immunology2014 Mar 175-8224594491
True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.Mocarski, Edward S; Kaiser, William J; Livingston-Rosanoff, Devon; Upton, Jason W; Daley-Bauer, Lisa PJournal of immunology (Baltimore, Md. : 1950)2014 Mar 12019-2624563506
Opioid prescribing by multiple providers in Medicare: retrospective observational study of insurance claims.Jena, Anupam B; Goldman, Dana; Weaver, Lesley; Karaca-Mandic, PinarBMJ (Clinical research ed.)2014g139324553363
Optical coherence contrast imaging using gold nanorods in living mice eyes.de la Zerda, Adam; Prabhulkar, Shradha; Perez, Victor L; Ruggeri, Marco; Paranjape, Amit S; Habte, Frezghi; Gambhir, Sanjiv S; Awdeh, Richard MClinical & experimental ophthalmology.2015 May;358-6624533647
Diffuse x-ray scattering to model protein motions.Wall, Michael E; Adams, Paul D; Fraser, James S; Sauter, Nicholas KStructure (London, England : 1993)2014 Feb 4182-424507780
A general framework for estimating the relative pathogenicity of human genetic variants.Kircher, Martin; Witten, Daniela M; Jain, Preti; O'Roak, Brian J; Cooper, Gregory M; Shendure, JayNature genetics2014 Mar310-524487276
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.Fenwick, R Bryn; van den Bedem, Henry; Fraser, James S; Wright, Peter EProceedings of the National Academy of Sciences of the United States of America2014 Jan 28E445-5424474795
Combinatorial therapy discovery using mixed integer linear programming.Pang, Kaifang; Wan, Ying-Wooi; Choi, William T; Donehower, Lawrence A; Sun, Jingchun; Pant, Dhruv; Liu, ZhandongBioinformatics (Oxford, England)2014 May 151456-6324463180
Does the Declining Lethality of Gunshot Injuries Mask a Rising Epidemic of Gun Violence in the United States?Jena, Anupam B; Sun, Eric C; Prasad, VinayJournal of general internal medicine2014 Jan 23NULL24452421
Animal reservoir, natural and socioeconomic variations and the transmission of hemorrhagic fever with renal syndrome in Chenzhou, China, 2006-2010.Xiao, Hong; Tian, Huai-Yu; Gao, Li-Dong; Liu, Hai-Ning; Duan, Liang-Song; Basta, Nicole; Cazelles, Bernard; Li, Xiu-Jun; Lin, Xiao-Ling; Wu, Hong-Wei; Chen, Bi-Yun; Yang, Hui-Suo; Xu, Bing; Grenfell, BryanPLoS neglected tropical diseases2014 Jane261524421910
Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia.Anticevic, Alan; Cole, Michael W; Repovs, Grega; Savic, Aleksandar; Driesen, Naomi R; Yang, Genevieve; Cho, Youngsun T; Murray, John D; Glahn, David C; Wang, Xiao-Jing; Krystal, John HFrontiers in psychiatry.2013 Dec 24;24399974
Careful use of science to advance the debate on the UK Cancer Drugs Fund.Lakdawalla, Darius N; Jena, Anupam B; Doctor, Jason NJAMA : the journal of the American Medical Association2014 Jan 125-624381964
Obesity reduces left ventricular strains, torsion, and synchrony in mouse models: a cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance study.Kramer, Sage P; Powell, David K; Haggerty, Christopher M; Binkley, Cassi M; Mattingly, Andrea C; Cassis, Lisa A; Epstein, Frederick H; Fornwalt, Brandon KJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance201310924380567
Protein structural ensembles are revealed by redefining X-ray electron density noise.Lang, P Therese; Holton, James M; Fraser, James S; Alber, TomProceedings of the National Academy of Sciences of the United States of America2014 Jan 7237-4224363322
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.Chen, Baohui; Gilbert, Luke A; Cimini, Beth A; Schnitzbauer, Joerg; Zhang, Wei; Li, Gene-Wei; Park, Jason; Blackburn, Elizabeth H; Weissman, Jonathan S; Qi, Lei S; Huang, BoCell2013 Dec 191479-9124360272
Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder.Anticevic, Alan; Hu, Sien; Zhang, Sheng; Savic, Aleksandar; Billingslea, Eileen; Wasylink, Suzanne; Repovs, Grega; Cole, Michael W; Bednarski, Sarah; Krystal, John H; Bloch, Michael H; Li, Chiang-Shan R; Pittenger, ChristopherBiological psychiatry.2014 Apr 15;24314349
Pd-Porphyrin-Cross-Linked Implantable Hydrogels with Oxygen-Responsive Phosphorescence.Huang, Haoyuan; Song, Wentao; Chen, Guanying; Reynard, Justin M; Ohulchanskyy, Tymish Y; Prasad, Paras N; Bright, Frank V; Lovell, Jonathan FAdvanced healthcare materials2013 Nov 20NULL24259519
Imaging the glycosylation state of cell surface glycoproteins by two-photon fluorescence lifetime imaging microscopy.Belardi, Brian; de la Zerda, Adam; Spiciarich, David R; Maund, Sophia L; Peehl, Donna M; Bertozzi, Carolyn RAngewandte Chemie (International ed. in English)2013 Dec 2314045-924259491
Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.Blum, Jordan M; Ano, Leonor; Li, Zhizhong; Van Mater, David; Bennett, Brian D; Sachdeva, Mohit; Lagutina, Irina; Zhang, Minsi; Mito, Jeffrey K; Dodd, Leslie G; Cardona, Diana M; Dodd, Rebecca D; Williams, Nerissa; Ma, Yan; Lepper, Christoph; Linardic, CorCell reports2013 Nov 27933-4024239359
Methods for identifying Neisseria meningitidis carriers: a multi-center study in the African meningitis belt.Basta, Nicole E; Stuart, James M; Nascimento, Maria C; Manigart, Olivier; Trotter, Caroline; Hassan-King, Musa; Chandramohan, Daniel; Sow, Samba O; Berthe, Abdoulaye; Bedru, Ahmed; Tekletsion, Yenenesh K; Collard, Jean-Marc; Jusot, Jean-Francois; Diallo, PloS one2013e7833624194921
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.Alenghat, Theresa; Osborne, Lisa C; Saenz, Steven A; Kobuley, Dmytro; Ziegler, Carly G K; Mullican, Shannon E; Choi, Inchan; Grunberg, Stephanie; Sinha, Rohini; Wynosky-Dolfi, Meghan; Snyder, Annelise; Giacomin, Paul R; Joyce, Karen L; Hoang, Tram B; BewtNature2013 Dec 5153-724185009
Editorial: New tricks for innate lymphoid cells.Sonnenberg, Gregory FJournal of leukocyte biology2013 Nov862-424179147
Yeast Oligo-Mediated Genome Engineering (YOGE).Dicarlo, James E; Conley, Andrew J; Penttila, Merja; Jantti, Jussi; Wang, Harris H; Church, George MACS synthetic biology2013 Nov 18NULL24160921
Mortality among high-risk patients with acute myocardial infarction admitted to U.S. Teaching-Intensive Hospitals in July: a retrospective observational study.Jena, Anupam B; Sun, Eric C; Romley, John ACirculation2013 Dec 242754-6324152859
Genomically recoded organisms expand biological functions.Lajoie, Marc J; Rovner, Alexis J; Goodman, Daniel B; Aerni, Hans-Rudolf; Haimovich, Adrian D; Kuznetsov, Gleb; Mercer, Jaron A; Wang, Harris H; Carr, Peter A; Mosberg, Joshua A; Rohland, Nadin; Schultz, Peter G; Jacobson, Joseph M; Rinehart, Jesse; ChurchScience (New York, N.Y.)2013 Oct 18357-6024136966
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Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1* via caspase-8 in dendritic cells.Antonopoulos, Christina; El Sanadi, Caroline; Kaiser, William J; Mocarski, Edward S; Dubyak, George RJournal of immunology (Baltimore, Md. : 1950)2013 Nov 14789-80324078693
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