Metabolomics Program Highlights
Using metabolomics to understand the interplay of antibiotics and a pathogenic bacterium that can live in the gut
Metabolomics Program Mentored Research Scientist Dr. Casey Theriot, utilizing the Michigan Regional Comprehensive Metabolomics Resource Center (MRC2 ), published in Nature Communications that metabolites produced by gut microbes change in response to antibiotic treatment and favor growth of the pathogenic bacterium C. difficile.
Researchers look at the relationship between metabolic health and the metabolites found in blood
New work from the NIH West Coast Metabolomics Center at UC Davis describes how the metabolites found in the blood of women who are obese, sedentary and insulin-resistant change after the women participate in a weight loss and exercise intervention. Some of the metabolites that changed were derived from the gut, and may have originated either from diet or from gut-dwelling microbes. By revealing an association between improved metabolic health and an altered metabolite profile, this study and others like it could help us understand, diagnose and treat complex metabolic disorders like type 2 diabetes mellitus. Click here to access the research article.
Researchers Investigate Lung Disorders Using Metabolomics
A publication from the University of Michigan Regional Comprehensive Metabolomics Research Core (RCMRC) offers insight into the lungs of patients with acute respiratory distress syndrome. View the article abstract here.
Call for Pilot and Feasibililty Project Applications from Regional Comprehensive Metabolomics Resource Cores
Pilot and Feasibility Projects
The six Regional Comprehensive Metabolomics Research Cores (RCMRCs) are accepting applications for exploratory biomedical research projects utilizing metabolomics technology. These Pilot and Feasibility studies (P&F) are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research.
These awards are intended to support projects that will provide preliminary data for new extramural proposal submission. The application deadline is March 15, 2014.
All basic, translational, or clinical investigators who are eligible to apply as a PI for NIH grants are invited to apply. Early stage investigators or those new to the metabolomics field are especially encouraged to apply.
Application Procedures for the RCMRCs
Application information for P&F studies at the Michigan Regional Comprehensive Metabolomics Research Core
Application information for P&F studies at the NIH West Coast Metabolomics Center at UC Davis
Application information for P&F studies at the NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International
Application information for P&F studies at the Southeast Center for Integrated Metabolomics
Application information for P&F studies at the Metabolomics Core at Mayo Clinic
Application information for P&F studies at the Resource Center for Stable Isotope-Resolved Metabolomics
Learn More about the RCMRCs
Michigan Regional Comprehensive Metabolomics Research Core (MRC2)
NIH West Coast Metabolomics Center at UC Davis
NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International (RTI RCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Metabolomics Core at Mayo Clinic
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)
Scientific Symposium on Metabolomics
Scientific Symposium: Metabolomics, the Underlying Basis of Disease was hosted at the University of Alabama-Birmingham School of Medicine. Both Dr. Stephen Barnes and Dr. Andrew Patterson grantees of the Metabolomics program presented at the symposium. An overview, agenda with copies of the presentations given at the Symposium can be found here.
Learn More About Metabolomics Initiatives
- The NIH Common Fund is taking a comprehensive approach to increasing the research capacity in metabolomics by funding a variety of initiatives in this area, including training, technology development, standards synthesis, and data sharing capability for this new field.
View the Metabolomics Press Release.
- The International Conference of the Metabolomics Society met in Washington, DC on June 2012. For conference information visitwww.metabolomics2012.org
- The National Institutes of Health Common Fund Working Group on Metabolomics organized a workshop on Metabolomics and Translational Research, in the spring of 2011. The goal of the workshop was to help NIH identify and prioritize opportunities to further the use of metabolomics in translational research across the interests of the entire NIH.
View the 2011 Meeting Report
Learn more about the Metabolomics Community