Program Snapshot

The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program aims to develop a “library” of molecular signatures that describes how different types of cells respond to a variety of perturbing agents. Phase 1 of the program is underway and focuses on the following activities:

• Large-scale production of perturbation-induced molecular and cellular signatures
• Creation of a database, common data standards and public user interface for accessing the data
• Computational tool development and integrative data analyses
• Development of new cost-effective, molecular and cellular phenotypic assays
• Integration of existing datasets into LINCS

Program Highlights

Overcoming Obstacles to Analyzing Complex Biological Data

Researchers supported through the Common Fund’s LINCS program are developing new adaptable approaches to store, analyze and extend complex biomedical data sets. The approach may someday prove useful for preclinical studies.