For additional information about the Workshop, please contact either Cristen Robinson or Anna Rossoshek at GTEXInfo@mail.nih.gov.
| Day 1: June 2, Monday | |||
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| 8:00 a.m. | Continental Breakfast | ||
| 8:30 a.m. | Francis Collins: Welcome and Introduction to Aims of GTEx Proposal | ||
| 9:00 a.m. | GWAS studies, eQTLs, and Beyond Cliona Molony John Hardy Discussion |
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| 10:00 a.m. | Coffee Break | ||
| 10:30 a.m. | Challenges of Obtaining Multiple, High-Quality Tissues for GTEx Carolyn Compton Mark Rubin John Lonsdale Discussion |
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| 11:30 a.m. | Lunch | ||
| 12:30 p.m. | Consideration of Ethical, Legal, and Social Implications (ELSI) Stuart Youngner Laura Beskow Discussion |
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| Breakout Sessions Most groups will be run twice, with different leaders and a different mix of people. Each group/session has an assigned note-taker and assigned leader. ELSI will be integrated into all group discussions |
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| 1:30 p.m. | Breakout Session I Group A: Statistical/Epidemiology Issues; Size, Statistical Power, Phenotypic Variables, Analytical Plans (Group Leaders: Nancy Cox, Manolis Detmitzakis, Richard Spielman) Group B: Building a Public Database of eQTL Data: Access and Analytical Tools (Group Leader: Ron Edgar) Group C: Procuring Tissues of High Quality: Setting Quality Standards (Group Leader: Ron Zielke) Group D: Laboratory Analysis of Tissues for Global RNA Expression: Methods and Quality Standards (Group Leaders: Martin Hirst) |
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| 3:00 p.m. | Coffee Break | ||
| 3:30 p.m. | Breakout Session II: (Most participants from Session I will join different groups in Session II.) Group A: Break into 2-3 sub-groups based on discussion during Session I » A1 sub-topic to be determined in Session I (Nancy Cox) » A2 sub-topic to be determined in Session I (Manolis Dermitzakis) » A3 sub-topic to be determined in Session I (Richard Spielman) Group C: Procuring Tissues of High Quality: Setting Quality Standards (Group Leader: Mark Sobel) Group D: Laboratory Analysis of Tissues for Global RNA Expression: Methods and Quality Standards (Group Leader: John Walker) |
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| 5:00 p.m. | Group Leaders and Scribes Review and Consolidate Notes | ||
| 6:00 p.m. | Meet and Greet (Atrium) | ||
| Day 2: Tuesday, June 3 | |||
| 8:00 a.m. | Continental Breakfast | ||
| 8:30 a.m. | Summarizing Results of Breakout Sessions | ||
| 8:30 a.m. | Group A Leaders | ||
| 9:00 a.m. | Group B Leaders | ||
| 10:00 a.m. | Coffee Break | ||
| 10:15 a.m. | Group C Leaders | ||
| 11:15 a.m. | Group D Leaders | ||
| 12 noon | Lunch | ||
| 1:30 p.m. | Drafting Recommendations for GTEx Proposal (30 minutes each) Chair: Francis Collins » Statistical/Epidemiology Issues » Public Database » Tissue Procurement » ELSI Considerations » Data Quality Standards » Laboratory Analyses |
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| 3:30 p.m. | End of Workshop | ||