Genotype-Tissue Expression (GTEx)

Science Publications


 
Marbled inflation from population structure in gene-based association studies with rare variants.
Liu, Qianying; Nicolae, Dan L; Chen, Lin S
Genetic epidemiology. 2013 Apr. 286-92 
PMID: 23468125 [PubMed]
Modeling causality for pairs of phenotypes in system genetics.
Neto, Elias Chaibub; Broman, Aimee T; Keller, Mark P; Attie, Alan D; Zhang, Bin; Zhu, Jun; Yandell, Brian S
Genetics. 2013 Mar. 1003-13 
PMID: 23288936 [PubMed]
Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.
Gamazon, Eric R; Pinto, Navin; Konkashbaev, Anuar; Im, Hae Kyung; Diskin, Sharon J; London, Wendy B; Maris, John M; Dolan, M Eileen; Cox, Nancy J; Cohn, Susan L
Journal of the National Cancer Institute. 2013 Feb 20. 302-9 
PMID: 23243203 [PubMed]
An exponential combination procedure for set-based association tests in sequencing studies.
Chen, Lin S; Hsu, Li; Gamazon, Eric R; Cox, Nancy J; Nicolae, Dan L
American journal of human genetics. 2012 Dec 7. 977-86 
PMID: 23159251 [PubMed]
Sex-biased genetic effects on gene regulation in humans.
Dimas, Antigone S; Nica, Alexandra C; Montgomery, Stephen B; Stranger, Barbara E; Raj, Towfique; Buil, Alfonso; Giger, Thomas; Lappalainen, Tuuli; Gutierrez-Arcelus, Maria; MuTHER Consortium; McCarthy, Mark I; Dermitzakis, Emmanouil T
Genome research. 2012 Dec. 2368-75 
PMID: 22960374 [PubMed]
The GEM mapper: fast, accurate and versatile alignment by filtration.
Marco-Sola, Santiago; Sammeth, Michael; Guigo, Roderic; Ribeca, Paolo
Nature methods. 2012 Dec. 1185-8 
PMID: 23103880 [PubMed]
Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets.
Tu, Zhidong; Keller, Mark P; Zhang, Chunsheng; Rabaglia, Mary E; Greenawalt, Danielle M; Yang, Xia; Wang, I-Ming; Dai, Hongyue; Bruss, Matthew D; Lum, Pek Y; Zhou, Yun-Ping; Kemp, Daniel M; Kendziorski, Christina; Yandell, Brian S; Attie, Alan D; Schadt, Eric E; Zhu, Jun
PLoS genetics. 2012 Dec. e1003107 
PMID: 23236292 [PubMed]
Controls of nucleosome positioning in the human genome.
Gaffney, Daniel J; McVicker, Graham; Pai, Athma A; Fondufe-Mittendorf, Yvonne N; Lewellen, Noah; Michelini, Katelyn; Widom, Jonathan; Gilad, Yoav; Pritchard, Jonathan K
PLoS genetics. 2012 Nov. e1003036 
PMID: 23166509 [PubMed]
Genetic risk factors for type 2 diabetes: a trans-regulatory genetic architecture?
Elbein, Steven C; Gamazon, Eric R; Das, Swapan K; Rasouli, Neda; Kern, Philip A; Cox, Nancy J
American journal of human genetics. 2012 Sep 7. 466-77 
PMID: 22958899 [PubMed]
Quantile-based permutation thresholds for quantitative trait loci hotspots.
Neto, Elias Chaibub; Keller, Mark P; Broman, Andrew F; Attie, Alan D; Jansen, Ritsert C; Broman, Karl W; Yandell, Brian S
Genetics. 2012 Aug. 1355-65 
PMID: 22661325 [PubMed]
Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.
Valdar, William; Sabourin, Jeremy; Nobel, Andrew; Holmes, Christopher C
Genetic epidemiology. 2012 Jul. 451-62 
PMID: 22549815 [PubMed]
Matrix eQTL: ultra fast eQTL analysis via large matrix operations.
Shabalin, Andrey A
Bioinformatics (Oxford, England). 2012 May 15. 1353-8 
PMID: 22492648 [PubMed]
On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.
Im, Hae Kyung; Gamazon, Eric R; Nicolae, Dan L; Cox, Nancy J
American journal of human genetics. 2012 Apr 6. 591-8 
PMID: 22463877 [PubMed]
Estimation of alternative splicing variability in human populations.
Gonzalez-Porta, Mar; Calvo, Miquel; Sammeth, Michael; Guigo, Roderic
Genome research. 2012 Mar. 528-38 
PMID: 22113879 [PubMed]
DNase I sensitivity QTLs are a major determinant of human expression variation.
Degner, Jacob F; Pai, Athma A; Pique-Regi, Roger; Veyrieras, Jean-Baptiste; Gaffney, Daniel J; Pickrell, Joseph K; De Leon, Sherryl; Michelini, Katelyn; Lewellen, Noah; Crawford, Gregory E; Stephens, Matthew; Gilad, Yoav; Pritchard, Jonathan K
Nature. 2012 Feb 16. 390-4 
PMID: 22307276 [PubMed]
seeQTL: a searchable database for human eQTLs.
Xia, Kai; Shabalin, Andrey A; Huang, Shunping; Madar, Vered; Zhou, Yi-Hui; Wang, Wei; Zou, Fei; Sun, Wei; Sullivan, Patrick F; Wright, Fred A
Bioinformatics (Oxford, England). 2012 Feb 1. 451-2 
PMID: 22171328 [PubMed]
Computational tools for discovery and interpretation of expression quantitative trait loci.
Wright, Fred A; Shabalin, Andrey A; Rusyn, Ivan
Pharmacogenomics. 2012 Feb. 343-52 
PMID: 22304583 [PubMed]
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, Koller DL, Scheftner WA, Coryell W, Rice J, Lawson WB, Nwulia EA, Hipolito M, Byerley W, McMahon FJ, Schulze TG, Berrettini WH, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB, Liu C.
Mol Psychiatry. 2012 Jan 3. 174 
PMID: 22212596 [PubMed]
Dissecting the regulatory architecture of gene expression QTLs.
Gaffney, Daniel J; Veyrieras, Jean-Baptiste; Degner, Jacob F; Pique-Regi, Roger; Pai, Athma A; Crawford, Gregory E; Stephens, Matthew; Gilad, Yoav; Pritchard, Jonathan K
Genome biology. 2012. R7 
PMID: 22293038 [PubMed]
Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
Veyrieras, Jean-Baptiste; Gaffney, Daniel J; Pickrell, Joseph K; Gilad, Yoav; Stephens, Matthew; Pritchard, Jonathan K
PloS one. 2012. e30629 
PMID: 22359548 [PubMed]
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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892