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National Technology Centers for Networks and Pathways

The Building Blocks, Biological Pathways and Networks program has transitioned from Common Fund support.  For more information, please visit https://commonfund.nih.gov/bbpn/index. Please note that since the Building Blocks, Biological Pathways and Networks program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis. 
Renewal of the National Technology Centers for Networks and Pathways Program (U54)
RFA-RM-08-021
PI Name Institution Name Title
BOEKE, JEF D. JOHNS HOPKINS UNIVERSITY Networks, Pathways and Dynamics of Lysine Modification
ROUT, MICHAEL P ROCKEFELLER UNIVERSITY New Tools for Exploring the Dynamic Interactome (Renewal)
WAGGONER, ALAN S CARNEGIE-MELLON UNIVERSITY Fluorescent Biosensors for Networks and Pathways

 

National Technology Centers for Networks and Pathways (U54)
RFA-RM-04-005
PI Name Institution Name Title
BOEKE, JEF D JOHNS HOPKINS UNIVERSITY Networks and Pathways of Lysine Modification
SMITH, JEFFREY W BURNHAM INSTITUTE Center on Proteolytic Pathways

 

National Technology Centers for Networks and Pathways (Re-issuance) (U54)
RFA-RM-04-019
PI Name Institution Name Title
LOEW, LESLIE M. UNIVERSITY OF CONNECTICUT SCH OF MED/DNT POLARITY IN NETWORKS AND PATHWAYS
ROUT, MICHAEL P. ROCKEFELLER UNIVERSITY New Tools for Exploring the Dynamic Interactome
WAGGONER, ALAN S. MELLON PITTS CORPORATION (MPC CORP) Flourescent Probes & Imaging for Networks & Pathways

Metabolomics Technology Development

Using Metabolomics to Investigate Biological Pathways and Networks (R01)
RFA-RM-06-010
PI Name Institution Name Title
BURANT, CHARLES F UNIVERSITY OF MICHIGAN AT ANN ARBOR Using Systems Biology to Understand Islet Adaptation and Failure Diabetes
CRAVATT, BENJAMIN F SCRIPPS RESEARCH INSTITUTE Chemical Probes for Metabolic Pathway Discovery in Human Disease
DOVICHI, NORMAN J UNIVERSITY OF WASHINGTON Glycolipid metabolism in single cells
FREYER, JAMES P LOS ALAMOS NAT SECTY-LOS ALAMOS NAT LAB Differential metabolic network analysis of tumor progression
FROMMER, WOLF B CARNEGIE INSTITUTION OF WASHINGTON, D.C. Sugar signaling networks detected by high content fluxomics
HAN, XIANLIN WASHINGTON UNIVERSITY Shotgun Lipidomics and Alterations in Sphingolipidomes in Alzheimer's Diseases
SWEEDLER, JONATHAN V UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN The Neurometabolome of a Sensory Neuronal Network

 

Metabolomics Technology Development (R21, R33)
RFA-RM-04-002
PI Name Institution Name Title
BREAKER, RONALD YALE UNIVERSITY Measuring Metabolites Using Riboswitch Reports
BROWN, TRUMAN R COLUMBIA UNIVERSITY HEALTH SCIENCES Metabolic Patterns in 1H NMR Spectra of Biofluids
BRUNENGRABER, HENRI CASE WESTERN RESERVE UNIVERSITY Dynamic Metabolomics via Isotopomer Analysis
DOVICHI, NORMAN J UNIVERSITY OF WASHINGTON GLYCOLIPID METABOLISM IN SINGLE CELLS
GRIFFIN, JULIAN L UNIVERSITY OF CAMBRIDGE Metabolomics and Metabolomic Compartmentation in the Brain
HILL, HERBERT H WASHINGTON STATE UNIVERSITY High Resolution Ion Mobility Mass Spectrometry (IMMS)
KLEINFELD, ALAN M FFA SCIENCES, LLC Fluorescent Probes for Hydrophobic Metabolites
LIAO, JAMES C UNIVERSITY OF CALIFORNIA LOS ANGELES Automated Chip-Based Metabolic Analysis
MATSON, WAYNE R ESA, INC Integrating LCE/LCM In a Single Metabolomics Plataform
REGNIER, FRED E PURDUE UNIVERSITY WEST LAFAYETTE Tools for Differential Metabolomics
SUSSMAN, MICHAEL R UNIVERSITY OF WISCONSON MADISON Isotope-Assisted Differential Metabolomics
SWEEDLER, JONATHAN V UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN Technologies for Cellular Neurometabolomics
WAGNER, GERHARD HARVARD UNIVERSITY (MEDICAL SCHOOL) Integrated & Sensitive Metabolomics Platform/Human disease
YORK, JOHN D DUKE UNIVERSITY Biological Oscilloscopes Spatio-Temporal Metabolomics

 

 

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